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Targets Recommended: TNF

25

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T76787 Conatumumab

TRAIL-R2 mAb,AMG 655

TNF Apoptosis
Conatumumab (AMG 655) 是一种靶向人死亡受体 5 (DR5,TRAILR2) 的单克隆激动剂抗体 ,对长型 DR5 的 Kd 为 1 nM, 对短型 DR5 的 Kd 0.8 nM。Conatumumab 通过半胱天冬酶激活在多种肿瘤类型中诱导细胞凋亡。Conatumumab 可用于研究晚期实体肿瘤。
T8969 API-1

NSC177223

Akt Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
API-1 (NSC-177223) 是Akt/PKB 抑制剂,可同 PH 结构域相结合并抑制 Akt 膜易位,有效降低 Akt 的磷酸化水平。它可选择性的抑制PKB,对 PKC 和 PKA 的激活无抑制作用。它可以和 TNF 相关的凋亡诱导配体协同作用从而诱导细胞凋亡。
T2065 Bioymifi

DR5 Activator

Apoptosis; TNF Apoptosis
Bioymifi (DR5 Activator) 是一种 TRAIL 受体DR5激活剂,与DR5的胞外结构域结合,Kd 为 1.2 μM,它可诱导 DR5 聚集,导致细胞凋亡。
T7001 TIC10

ONC-201

Apoptosis; TNF Apoptosis
TIC10 (ONC-201) 是一种有口服活性的, 可透过血脑屏障的,肿瘤坏死因子相关的凋亡诱导配体 TRAIL 诱导剂。它通过抑制 Akt 和 ERK,从而激活 Foxo3a 并显著诱导细胞表面 TRAIL
T16392 ONC206

Dopamine Receptor GPCR/G Protein; Neuroscience
ONC206 是一种 ONC201 的类似物,是一种多巴胺 D2- 样受体 (DRD2/3/4) 的选择性拮抗剂,其拮抗作用在纳摩尔级别。它具有广谱抗肿瘤活性。
T76815 Lexatumumab

ETR2-ST01,DR5 mAB,HGS-ETR 2

Apoptosis Apoptosis
Lexatumumab (HGS-ETR 2) 是一种靶向 TRAIL 受体 2 的人激动性单克隆抗体,具有抗癌活性, 在恶性间皮瘤中诱导细胞凋亡 (apoptosis)。Lexatumumab 可用于研究恶性胸膜间皮瘤 (MPM)。
T6705 TIC10 Isomer

ONC201 isomer,TIC10 Analogue

Others Others
TIC10 Isomer (ONC201 isomer) 是一种 TIC10 的异构体。它不能诱导 TRIAL 表达的生物学活性。
T4423 LY 303511 hydrochloride

LY303511 hydrochloride

Potassium Channel; TNF; mTOR Apoptosis; Membrane transporter/Ion channel; PI3K/Akt/mTOR signaling
LY 303511 hydrochloride 是LY294002 的一种结构类似物。LY 303511 hydrochloride 可增强 SHEP-1 神经母细胞瘤细胞的TRAIL 敏感性,还可逆地阻断 MIN6 胰岛瘤细胞中的K+电流。
T6776 BAY 61-3606 dihydrochloride

BAY 61-3606,BAY-61-3606 dihydrochloride

Apoptosis; Syk Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
BAY 61-3606 dihydrochloride (BAY 61-3606) 是一种口服有效的,ATP 竞争性的,可逆的选择性Syk 抑制剂。它降低神经母细胞瘤细胞中的 ERK1/2 和 Akt 磷酸化,也降低 K-rn 细胞裂解物中 Syk 磷酸化。它作用于乳腺癌细胞,通过下调 Mcl-1 促进 TRAIL 诱导的细胞凋亡。
T4263 BAY 61-3606

2-[[7-(3,4-二甲氧基苯基)咪唑并[1,2-C]嘧啶-5-基]氨基]-3-吡啶甲酰胺,Syk inhibitor IV

Apoptosis; Syk Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
BAY 61-3606 (Syk inhibitor IV) 是一种具有口服活性的,ATP 竞争性的可逆选择性Syk 抑制剂。它作用于乳腺癌细胞,通过下调 Mcl-1 促进 TRAIL 诱导的细胞凋亡。它降低神经母细胞瘤细胞中的 ERK1/2 和 Akt 磷酸化,也降低 K-rn 细胞裂解物中 Syk 磷酸化。
T33892 PBOX-15

PBOX-15 is a novel microtubule-targeting agent that induces apoptosis, upregulates death receptors, and enhances TRAIL-mediated apoptosis in multiple myeloma cells. It also inhibits T cell migration through post-translational modification of tubulin. Pbox
T70352 PH11

PH11 is a novel Focal Adhesion Kinase (FAK) inhibitor. PH11 restores TRAIL apoptotic pathway in PANC-1 cells through down-regulation of c-FLIP via inhibition of FAK and the phosphatidylinositol-3 kinase (PI3K)/AKT pathways. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) emerges as one of the most-promising experimental cancer therapeutic drugs and is currently being tested in clinical trials. However, both intrinsic and acquired resistance of human cancer cells to TRAIL...
T23859 CaspPro

C-2,C 2,Casp-Pro,Casp Pro,C2

CaspPro is a selective activator of caspase 8 that acts by potentiating TRAIL-induced cell death.
T26709 Azadirone

Azadirone is a limonoid tetranortriterpene. Azadirone can sensitize cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR4 and DR5 signaling, down-regulation of cell survival prot
T32072 Hexyl decanoate

Decanoic acid hexyl ester

Hexyl decanoate, the first trail pheromone compound identified in a stingless bee, Trigona recursa. Hexyl decanoate is dominant component of gland secretions.
T15723 LBW242

Others Others
LBW242 is a 3-mer and Smac mimetic and is an effective and orally active proapoptotic IAP inhibitor. LBW242 has activity against multiple myeloma and potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cells. LBW242 displays effec
T35729 Nemadipine-A

Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel α1-subunit in the C. elegans genome. It also inhibits L-type calcium channels in chick ciliary neurons. Nemadipine A increases TRAIL-induced cytotoxicity and synergistically enhances caspase-8 and caspase-3 activation in a concentration-dependent manner in H1299 lung adenocarcinoma cells. It ...
T11682 Isofistularin-3

Others Others
Isofistularin-3, as a DNA demethylating agent, induces cell cycle arrest and sensitization to TRAIL in cancer cells. Isofistularin-3 can be used as an ADC cytotoxin.Isofistularin-3 is a direct, DNA-competitive DNMT1 inhibitor, with an IC50 of 13.5 μM.
T37837 2-Methylhexacosane

2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone.1,2It has been found in the cuticle ofM. dasystomusfemales, but not males, where it contributes to the mating behavior of males, as well as inD. melanogasterfemales where it modulates aggression of males towards females. 2-methylhexacosane has also been found in yellow jacket (V. vulgaris) trail extracts.3 1.Spikes, A.E., Pashen, M.A., Millar, J.G., et al.First contact pheromone identified for a longhorned beetle (Coleoptera: ...
T78715 MS78

MS78为一种乙酰化靶向嵌合体(AceTAC),其功能是招募组蛋白乙酰转移酶p300/CBP以乙酰化p53肿瘤抑制蛋白的p53Y220C突变体。通过该作用,MS78能够上调TRAIL凋亡基因,同时下调DNA损伤反应信号通路。此化合物结构包含CBP/p300结合物、p53Y220C结合物及linker。
T70377 BAY 61-3606 HCl

BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was shown to suppress antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema. It can also sensitize MCF-7 breast cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis by inhibiting Cdk9. This compound has been used i...
T36890 A 410099.1

High affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells. Oost et al (2004) Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. J.Med.Chem. 47 4417 PMID:15317454 |Loeder et al (2009) A n...
T2434 LY 303511

Potassium Channel; TNF; mTOR Apoptosis; Membrane transporter/Ion channel; PI3K/Akt/mTOR signaling
LY303511 是 LY294002 的结构类似物,可增强 SHEP-1 神经母细胞瘤细胞的TRAIL 敏感性,还可逆地阻断 MIN6 胰岛瘤细胞中的K+电流,IC50为64.6±9.1 μM。
T36820 Fluphenazine-N-2-chloroethane (hydrochloride)

Fluphenazine is a traditional antipsychotic compound that tightly binds the dopamine D2 receptor (Ki = 0.55 nM) and also reversibly inhibits calmodulin at micromolar concentrations. Fluphenazine-N-2-chloroethane is a derivative of fluphenazine that contains an alkylating chlorethylamine chain, which produces irreversible protein binding. It is a relatively selective, irreversible antagonist of D2 receptors both in vitro (IC50 = 100 nM) and in vivo, inactivating approximately 90% of D2 receptors ...
T35558 KAAD-Cyclopamine

Cyclopamine-KAAD is a potent inhibitor of hedgehog signaling with an IC50 value of 20 nM in a Shh-LIGHT2 assay. It blocks binding of BODIPY-cyclopamine to cells expressing Smoothened (Smo) in a dose-dependent manner. Cyclopamine-KAAD is cell-permeable and binds to SmoA1 to promote its exit from the endoplasmic reticulum. It inhibits the invasion and migration (45.9 and 43.3% inhibition, respectively) of Bel-7402 hepatocarcinoma cells and decreases the expression of nuclear glioma-associated onco...

化合物

Conatumumab
Cat.No: T76787
Synonym: TRAIL-R2 mAb,AMG 655
Target: TNF
API-1
Cat.No: T8969
Synonym: NSC177223
Target: Akt
Bioymifi
Cat.No: T2065
Synonym: DR5 Activator
Target: Apoptosis, TNF
TIC10
Cat.No: T7001
Synonym: ONC-201
Target: Apoptosis, TNF
ONC206
Cat.No: T16392
Synonym:
Target: Dopamine Receptor
Lexatumumab
Cat.No: T76815
Synonym: ETR2-ST01,DR5 mAB,HGS-ETR 2
Target: Apoptosis
TIC10 Isomer
Cat.No: T6705
Synonym: ONC201 isomer,TIC10 Analogue
Target: Others
LY 303511 hydrochloride
Cat.No: T4423
Synonym: LY303511 hydrochloride
Target: Potassium Channel, TNF, mTOR
BAY 61-3606 dihydrochloride
Cat.No: T6776
Synonym: BAY 61-3606,BAY-61-3606 dihydrochloride
Target: Apoptosis, Syk
BAY 61-3606
Cat.No: T4263
Synonym: 2-[[7-(3,4-二甲氧基苯基)咪唑并[1,2-C]嘧啶-5-基]氨基]-3-吡啶甲酰胺,Syk inhibitor IV
Target: Apoptosis, Syk
PBOX-15
Cat.No: T33892
Synonym:
Target:
PH11
Cat.No: T70352
Synonym:
Target:
CaspPro
Cat.No: T23859
Synonym: C-2,C 2,Casp-Pro,Casp Pro,C2
Target:
Azadirone
Cat.No: T26709
Synonym:
Target:
Hexyl decanoate
Cat.No: T32072
Synonym: Decanoic acid hexyl ester
Target:
LBW242
Cat.No: T15723
Synonym:
Target: Others
Nemadipine-A
Cat.No: T35729
Synonym:
Target:
Isofistularin-3
Cat.No: T11682
Synonym:
Target: Others
2-Methylhexacosane
Cat.No: T37837
Synonym:
Target:
MS78
Cat.No: T78715
Synonym:
Target:
BAY 61-3606 HCl
Cat.No: T70377
Synonym:
Target:
A 410099.1
Cat.No: T36890
Synonym:
Target:
LY 303511
Cat.No: T2434
Synonym:
Target: Potassium Channel, TNF, mTOR
Fluphenazine-N-2-chloroethane (hydrochloride)
Cat.No: T36820
Synonym:
Target:
KAAD-Cyclopamine
Cat.No: T35558
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3862 Irigenin

NF-κB; Integrin Cytoskeletal Signaling; NF-κB
Irigenin 可通过特异性和选择性地阻断 Extra Domain A 域的 C-C 环上α9β1和α4β1整合素结合位点,介导其抗转移作用。可通过增强胃癌细胞中促凋亡分子的表达来敏化 TRAIL 诱导的凋亡,具有抗癌作用。
T30969 Clitocine

Apoptosis; BCL Apoptosis
Clitocine 是一种来从蘑菇中提取的一种腺苷类似物,是一种有效的转录通读剂,是一种无义突变的抑制剂,具有抗癌活性,可诱导携带 p53 无义突变等位基因的细胞产生 p53 蛋白。Clitocine 通过促进 Mcl-1 降解来增强 TRAIL 介导的人结肠癌细胞凋亡。
T82578 Desacetylxanthanol

Desacetylxanthanol (Compound 4),源自Xanthium strumarium的倍半萜类化合物,展现出抗肿瘤坏死因子相关凋亡诱导配体(TRAIL)活性。
TN4038 Eupatolide

TNF; NOS; NF-κB; ROS; MAPK; Akt; COX; DNA/RNA Synthesis; Nrf2; PDGFR; NO Synthase; Prostaglandin Receptor; Autophagy Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; MAPK; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Eupatolide 是从 Inula japonica 的花中分离出来的,具有抗炎活性。 Eupatolide 可用于研究乳腺癌细胞对 TRAIL 的耐药性。
T21577 Narasin (sodium salt)

Naracin sodium salt,naransin sodium,海南霉素,HainanMycin

NF-κB NF-κB
Narasin (sodium salt) (HainanMycin) 通过神经胶质瘤细胞中的 ER 应激诱导肿瘤坏死因子相关凋亡诱导配体 (TRAIL) 介导的细胞凋亡,并通过抑制 IκBα 的磷酸化来抑制 NF-κB 信号传导。

天然产物

Irigenin
Cat.No: T3862
Synonym:
Target: NF-κB, Integrin
Clitocine
Cat.No: T30969
Synonym:
Target: Apoptosis, BCL
Desacetylxanthanol
Cat.No: T82578
Synonym:
Target:
Eupatolide
Cat.No: TN4038
Synonym:
Target: TNF, NOS, NF-κB, ROS, MAPK, Akt, COX, DNA/RNA Synthesis, Nrf2, PDGFR, NO Synthase, Prostaglandin Receptor, Autophagy
Narasin (sodium salt)
Cat.No: T21577
Synonym: Naracin sodium salt,naransin sodium,海南霉素,HainanMycin
Target: NF-κB
Cat. No. Product Name Species Expression System
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His)

KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPK-00708 TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)

TRAIL R1,APO2,DR4,CD261,TRAIL-R,TNFRSF10A,...

Human HEK293 Cells
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations.
TMPK-00706 TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi)

DR4,MGC9365,TNFRSF10A,TRAIL-R,TRAIL R1,CD2...

Human HEK293 Cells
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220.
TMPJ-00418 TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)

Decoy Receptor 1,Antagonist Decoy Receptor for TRAIL

Human HEK293 Cells
Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
TMPK-00171 TRAIL Trimer Protein, Human, Recombinant (His & Flag)

TRAIL,Apo-2L,APO2L,TL2,Apo-2 ligand,CD253,TNFSF10

Human HEK293 Cells
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the development of TRAIL-based cancer therapies, which include recombinant forms of TRAIL, TRAIL receptor agonists, and other therapeutic agents.
TMPJ-00655 TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His)

TRAIL-R1,TNFRSF10A,cytotoxic TRAIL recepto...

Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF...
TMPY-04722 DcR1/TRAILR3 Protein, Human, Recombinant (His)

TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR1-TNFR...

Human HEK293 Cells
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
TMPK-00707 TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated

TNFRSF10A,CD261,DR4,APO2,TRAIL-R,MGC9365,TRAIL<...

Human HEK293 Cells
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220.
TMPK-00277 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)

TRAIL R2,TNFRSF10B,TRICK2,KILLER,DR5,TRAIL...

Human HEK293 Cells
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
TMPJ-00276 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His)

DR5,TRAILR2,TRICK2,TNFRSF10B,KILLER,TNF-Related Apo...

Human HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 49 KDa and the accession number is O14763.
TMPY-02233 TRAIL/TNFSF10 Protein, Human, Recombinant

TL2,CD253,tumor necrosis factor (ligand) superfamily, member...

Human E. coli
TRAIL/TNFSF10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P50591.
TMPK-00276 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)

ZTNFR9,DR5TRICK2B,DR5,TRAIL receptor 2,TRICKB,TNFRS...

Human HEK293 Cells
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
TMPY-05481 DcR2/TRAIL R4 Protein, Human, Recombinant (hFc)

TRUNDD,TRAIL-R4,tumor necrosis factor receptor supe...

Human HEK293 Cells
DcR2/TRAIL R4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.5 kDa and the accession number is Q9UBN6.
TMPY-05388 DR5/TRAIL R2 Protein, Human, Recombinant (hFc)

tumor necrosis factor receptor superfamily, member 10b,T...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is AAB67103.1.
TMPJ-00275 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated

DR5,Tumor Necrosis Factor Receptor Superfamily Member 10B,

Human HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 18-25 KDa and the accession number is O14763.
TMPY-05477 DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated

DR5,tumor necrosis factor receptor superfamily, member 10b,T...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.8 kDa and the accession number is O14763-1.
TMPY-02784 TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His)

A330042I21Rik,tumor necrosis factor (ligand) superfamily, me...

Mouse E. coli
TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.2 kDa and the accession number is P50592.
TMPJ-00430 TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His)

Death Receptor 5,TRAILR2,CD262,DR5,TNFRSF10B,TR...

Cynomolgus HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 22-30 KDa and the accession number is A0A2K5TXK0.
TMPY-01381 DcR2/TRAIL R4 Protein, Human, Recombinant (His)

CD264,TRAILR4,tumor necrosis factor receptor superf...

Human HEK293 Cells
DcR2/TRAIL R4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is Q9UBN6.
TMPY-06835 DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated

TRICK2A,DR5,tumor necrosis factor receptor superfamily, memb...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.54 kDa and the accession number is NP_003833.4.
TMPY-02944 TRAIL/TNFSF10 Protein, Rhesus, Recombinant

tumor necrosis factor (ligand) superfamily, member 10

Rhesus E. coli
TRAIL/TNFSF10 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.6 kDa and the accession number is F6S9W7.
TMPY-01720 DR4/TRAIL R1 Protein, Human, Recombinant (His)

APO2,tumor necrosis factor receptor superfamily member 10a,<...

Human HEK293 Cells
DR4/TRAIL R1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O00220.
TMPY-01437 DR5/TRAIL R2 Protein, Mouse, Recombinant (His)

TRAILR2,MK,TRICKB,TRICK2B,TRICK2A,Ly98,DR5,KILLER,t...

Mouse HEK293 Cells
DR5/TRAIL R2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is Q9QZM4.
TMPY-03317 DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc)

tumor necrosis factor receptor superfamily, member 10d, deco...

Rhesus HEK293 Cells
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is XP_001107922.1.
TMPY-01719 DR4/TRAIL R1 Protein, Human, Recombinant (hFc)

TRAILR1,tumor necrosis factor receptor superfamily ...

Human HEK293 Cells
DR4/TRAIL R1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is O00220.
TMPY-01452 DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)

TRICK2B,DR5,tumor necrosis factor receptor superfamily, memb...

Mouse HEK293 Cells
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 41.8 kDa and the accession number is Q9QZM4.
TMPY-03318 DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His)

tumor necrosis factor receptor superfamily, member 10d, deco...

Rhesus HEK293 Cells
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is XP_001107922.1.
TMPK-00248 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)

DCR2,TNFRSF10D,RSF10D,CD264,TRUNDD,TRAILR4

Human HEK293 Cells
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 19.4 kDa and t...
TMPJ-00246 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)

MK,CD262,Tnfrsf10b,Dr5,Tumor necrosis factor receptor superf...

Mouse HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-75 KDa and the accession number is Q9QZM4.
TMPJ-00245 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated

Dr5,CD262,Death receptor 5,Tnfrsf10b,Killer,MK,Tumor necrosi...

Mouse HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 20-40 KDa and the accession number is Q9QZM4.
TMPK-00249 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated

TNFRSF10D,CD264,TRUNDD,DCR2,RSF10D,TRAILR4

Human HEK293 Cells
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is ...
TMPJ-00253 OPG Protein, Mouse, Recombinant (His)

Opg,Ocif,Tnfrsf11b,Osteoclastogenesis inhibitory factor,Oste...

Mouse HEK293 Cells
Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG ...
TMPH-03226 Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)

RABV E. coli
Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.9 kDa and the accessio...
TMPH-03225 Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc)

RABV E. coli
Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa an...
TMPH-01552 IRF1 Protein, Human, Recombinant (GST & His)

Human Baculovirus Insect Cells
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired imm...

重组蛋白

DR5/TRAIL R2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01185
Species: Human
Expression System: HEK293 Cells
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00708
Species: Human
Expression System: HEK293 Cells
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00706
Species: Human
Expression System: HEK293 Cells
TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00418
Species: Human
Expression System: HEK293 Cells
TRAIL Trimer Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00171
Species: Human
Expression System: HEK293 Cells
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His)
Cat.No: TMPJ-00655
Species: Human
Expression System: HEK293 Cells
DcR1/TRAILR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04722
Species: Human
Expression System: HEK293 Cells
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00707
Species: Human
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00277
Species: Human
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00276
Species: Human
Expression System: HEK293 Cells
TRAIL/TNFSF10 Protein, Human, Recombinant
Cat.No: TMPY-02233
Species: Human
Expression System: E. coli
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00276
Species: Human
Expression System: HEK293 Cells
DcR2/TRAIL R4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05481
Species: Human
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05388
Species: Human
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00275
Species: Human
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05477
Species: Human
Expression System: HEK293 Cells
TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His)
Cat.No: TMPY-02784
Species: Mouse
Expression System: E. coli
TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00430
Species: Cynomolgus
Expression System: HEK293 Cells
DcR2/TRAIL R4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01381
Species: Human
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06835
Species: Human
Expression System: HEK293 Cells
TRAIL/TNFSF10 Protein, Rhesus, Recombinant
Cat.No: TMPY-02944
Species: Rhesus
Expression System: E. coli
DR4/TRAIL R1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01720
Species: Human
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01437
Species: Mouse
Expression System: HEK293 Cells
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03317
Species: Rhesus
Expression System: HEK293 Cells
DR4/TRAIL R1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01719
Species: Human
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-01452
Species: Mouse
Expression System: HEK293 Cells
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-03318
Species: Rhesus
Expression System: HEK293 Cells
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00248
Species: Human
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00246
Species: Mouse
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00245
Species: Mouse
Expression System: HEK293 Cells
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00249
Species: Human
Expression System: HEK293 Cells
OPG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00253
Species: Mouse
Expression System: HEK293 Cells
Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)
Cat.No: TMPH-03226
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc)
Cat.No: TMPH-03225
Species: RABV
Expression System: E. coli
IRF1 Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01552
Species: Human
Expression System: Baculovirus Insect Cells
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