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Cat. No. Product Name Target Signaling Pathways
T22842 HTMT dimaleate

HTMT马来酸氢盐,Histamine Trifluoromethyl Toluidide Dimaleate

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) 是一种 H1 和 H2 受体激动剂。在自然抑制细胞中，它在 H2 受体介导的效应中的活性是组胺的 4 x 104倍。
T38634 Histamine H4 receptor antagonist-1

Histamine H4 receptor antagonist-1
Histamine H4 receptor antagonist-1 is a potent antagonist of the histamine H4 receptor.
T8439 Clobenpropit dihydrobromide

Apoptosis; Histamine Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Clobenpropit dihydrobromide 是一种组胺H3R 拮抗剂/反向激动剂。它与 5-HT3 受体和 α2A/α2C 肾上腺素受体结合，对组胺H4受体起部分激动剂的作用，还能促进凋亡。
T9717 Chlorcyclizine

HCV Protease; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Chlorcyclizine 是一种有效的组胺 H1拮抗剂。
T24698 (R)-(-)-α-Methylhistamine dihydrochloride

HISTAMINE DIHYDROCHLORIDE R(-)-A-METHYL
R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.
T9353 OXOMEMAZINE

AChR; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Oxomemazine 是毒菌碱 M1 受体的选择性拮抗剂，具有明显的抗毒蕈碱活性。它是基于吩噻嗪的组胺 H1 受体阻滞剂，是抗组胺和抗胆碱能试剂，可用于咳嗽相关研究。
T32436 L 1935

Compound l1935,L-1935,Histamine-liberator L 1935,L1935
L 1935 is a type of powerful histamine-liberator.
T10680 Carebastine

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Carebastine 是 Ebastine 的活性代谢产物，可抑制巨噬细胞移动抑制因子的表达。它是组胺 H1 受体拮抗剂，可抑制 VEGF 诱导的 HUVEC 和 HPAEC 增殖，迁移和血管生成。
T22724 Dimaprit dihydrochloride

NOS; NO Synthase; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Dimaprit dihydrochloride 是组胺H2受体的一种选择性激动剂，可刺激胃酸的分泌。它还抑制nNOS，IC50值为 49 μM。
T4563 Thonzylamine

neohetramine,松齐拉敏

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Thonzylamine (neohetramine) 是可口服的H1组胺受体拮抗剂，具有抗组胺和抗过敏特性，可用于鼻充血、过敏性结膜炎和其他过敏性疾病的研究。
T11723L JNJ-39758979

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
JNJ-39758979是一种选择性的、高亲和力的、可口服的组胺 H4 受体拮抗剂，具有抗炎和止痒作用，对人、小鼠和猴子的组胺 H4 受体的 Ki 值分别为 12.5、5.3 和 25 nM。它对组胺诱导的 cAMP 抑制作用具有拮抗作用，pA2 为 7.9。
T7477 Antazoline

Others Others
Antazoline 具有抗组胺和抗胆碱能作用。它用于治疗各种心律失常。
T4196 Betahistine EP Impurity C

NSC19005

 Others; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience; Others
Betahistine EP Impurity C (NSC19005) 是 Betahistine 的杂质。 Betahistine 是可口服的组胺 H1 受体激动剂和 H3 受体的拮抗剂，可用作血管扩张剂，用于类风湿性关节炎的研究。
T4250 Bilastine

比拉斯汀,Bilaxten

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Bilastine (Bilaxten) 是新型抗组胺药，对H1组胺受体具有高度选择性，起效快，作用时间长的特性，可用于变应性鼻结膜炎和荨麻疹。
T7564 Chlorphenoxamine

Contristamine,氯苯沙明

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Chlorphenoxamine (Contristamine) 是一种抗组胺药和抗胆碱能药，用作止痒药和抗帕金森病药。
T36949 Niaprazine

5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Niaprazine 是有效的组胺 H1 受体拮抗剂，具有抗组胺和抗血清素活性。Niaprazine 在睡眠障碍方面有研究的价值。
T2004 Ciproxifan maleate

FUB 359 maleate,FUB 359

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Ciproxifan maleate (FUB 359) 是一种选择性的，可口服和竞争性的组胺H3受体拮抗剂，IC50值为 9.2 nM。它对其他受体亚型的表观亲和力低，可用于研究衰老性疾病和阿尔兹海默症。
T0081 Lafutidine

拉呋替丁,FRG-8813

 5-HT Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Lafutidine (FRG-8813) 是一种组胺受体 H2RA 拮抗剂，可抑制胃酸分泌，具有胃粘膜保护作用，可用于研究胃食管反流疾病。
T1278 Astemizole

Laridal,Histaminos,Paralergin,阿司咪唑

 Potassium Channel; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
Astemizole (Laridal) 是一种长效、非镇静抗组胺药，用于治疗季节性过敏性鼻炎、哮喘、过敏性结膜炎和慢性特发性荨麻疹。它是组胺 H1 受体的拮抗剂，IC50值为 4 nM，还阻断 hERG K+通道，IC50值为 0.9 nM，具有抗胆碱能和止痒作用。
T4099 S 38093

S38093,S-38093

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
S 38093 是一种可透过大脑的，可口服的组胺 H3 受体拮抗剂，对大小鼠和人的 H3 受体具有不同的亲和力，Ki 值分别为 8.8、1.44 和 1.2 µM。
T7085 Mebhydrolin

Mebhydroline,美海屈林

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Mebhydrolin (Mebhydroline) 是组胺H1受体的一种特异性拮抗剂。
T3963 VUF10460

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
VUF10460 是一种非咪唑组胺 H4 受体激动剂，与大鼠H4受体结合的pKi 值为7.46。
T25180 Bromodiphenhydramine hydrochloride

Others Others
Bromodiphenhydramine hydrochloride 是一种控制皮肤的新型抗组胺药。
T4566 Lodoxamide

Lodoxamidum,洛草氨酸

 GPR; Histamine Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Lodoxamide (Lodoxamidum) 是一种抗过敏药物，作为肥大细胞稳定剂，对治疗哮喘和过敏性结膜炎有效。
T8514 LML134

LML-134

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
LML134 (LML-134) 是一种可口服的高选择性组胺 H3 受体反向激动剂，有用于过度睡眠障碍的潜力，对 hH3R 的 cAMP 和 bdg 的Kis 分别为 0.3 和 12 nM。
T22713 Decloxizine

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Decloxizine 是一种组胺受体H1拮抗剂。
T5829 H4 Receptor antagonist 1

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
H4 Receptor antagonist 1 是选择性组胺 H4受体反向激动剂，其IC50值为19 nM。
T4551 Acrivastine

Acrivastin,阿伐斯汀,BW825C,Semprex

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Acrivastine (Acrivastin) 是一种短效组胺 1 受体拮抗剂，可用于研究过敏性鼻炎。
T8548 Metoprine

Histone Methyltransferase; Antifolate; Histamine Receptor Cell Cycle/Checkpoint; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Metoprine 是一种有效的组胺 N-甲基转移酶抑制剂，具有抗肿瘤活性。它是一种二氨基嘧啶衍生物，可以透过血脑屏障，并通过抑制 HMT 增加脑组胺水平。
T7413 JNJ-5207852

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
JNJ-5207852 是一种新型的非咪唑组胺 H3 受体拮抗剂，其对大鼠和人 H3 受体的 pKi 值分别为 8.9 和9.24。
T22746 Tesmilifene fumarate

DPPE fumarate

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Tesmilifene fumarate (DPPE fumarate) 是一种 H1C 受体拮抗剂，可增强化疗的细胞毒性且保护正常细胞。
TQ0066 GSK189254A

GSK189254

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
GSK189254A (GSK189254) 是一种有效的特异性组胺 H3 受体拮抗剂，对人类和大鼠H3的pKi 值分别为9.59到9.90和8.51到9.17之间。
T12489 Pimethixene

Calmixen,匹美噻吨,Pimetixene

 Dopamine Receptor; 5-HT Receptor; AChR; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Pimethixene (Calmixen) 是抗组胺和抗血清素剂，用作抗偏头疼剂。它是高效多靶点拮抗剂。
T1469 Levocetirizine

Levocetirizine HCl,左西替利嗪

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Levocetirizine 是一种组胺 H1 受体拮抗剂，可用于研究变应性鼻炎和慢性特发性荨麻疹。它是一种抗组胺剂，是 Cetirizine 的 R 对映体，对组胺 H1 受体的亲和力高于 (S)-Cetirizine。
T19680 Zotepine

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Zotepine 是一种抗精神病剂，是有效的5-HT2A、5-HT2C、组胺H1、α1-肾上腺素能和多巴胺D2受体拮抗剂，Kd 值分别为 2.6、3.2、3.3、7.3 和 8 nM。它在体内表现出抗抑郁和抗焦虑作用。
T0053 Hydroxyzine Pamoate

Hydroxyzine embonate,双羟萘酸羟嗪,Bobsule,Equipose

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Hydroxyzine Pamoate (Bobsule) 是一种组胺 H1 受体拮抗剂，可有效治疗慢性荨麻疹、皮炎和组胺介导的瘙痒。它可作为止吐剂和镇静剂，缓解焦虑和紧张。
T2533 Alcaftadine

R89674,Lastacaft,阿卡他定

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Alcaftadine (Lastacaft) 是一种 H1 组胺受体拮抗剂，用于预防与过敏性结膜炎相关的瘙痒。它是一种广谱抗组胺剂，对组胺H1和H2受体具有高亲和力，对H4受体的亲和力较低，还具有调节免疫细胞募集和肥大细胞稳定的作用。
T7524 Metiamide

甲硫米特,SK&F 92058

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Metiamide (SK&F 92058) 是一种组胺H2受体拮抗剂。
T15195 Ebrotidine

FI3542,乙溴替丁

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Ebrotidine (FI3542) 是有效的、竞争性的H2受体的拮抗剂，Ki 为127.5nM。Ebrotidine 具有抗分泌活性，可用于胃保护。
T0074 Chlorprothixene

Truxal,Clorprotixeno,Taractan,氯普噻吨

 Dopamine Receptor; 5-HT Receptor; Antibacterial; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Chlorprothixene (Truxal) 是一种多巴胺和组胺受体拮抗剂，具有抗精神病作用。它高亲和力地结合人 D1，D2，D3，D5，H1 受体，Ki 分别为 18 nM，2.96 nM，4.56 nM，9 nM 和 3.75 nM。
T3979 Emedastine

LY188695,依美斯汀,Emadine

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Emedastine (LY188695) 是一种可口服的，选择性和高亲和力的组胺 H1受体拮抗剂，Ki 值为 1.3 nM。它是苯并咪唑衍生物，可用于过敏性鼻炎、过敏性皮肤疾病和过敏性结膜炎的研究。
T1627 Famotidine

MK-208,法莫替丁

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Famotidine (MK-208) 是一种具有抗酸活性的丙脒和组胺 H2 受体拮抗剂。
T0298 Dimenhydrinate

茶苯海明,Dramamine,Chloranautine,乘晕宁,Vomex A

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Dimenhydrinate (Vomex A) 是一种乙醇胺和组胺拮抗剂，具有抗过敏活性，可作为抗催吐剂。
T0445L Promethazine hydrochloride

盐酸异丙嗪,Promethazine HCl,Phenergan

 Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Promethazine hydrochloride (Promethazine HCl) 是抗组胺药物，是 H1 受体的强拮抗剂和 mACh 受体的中度拮抗剂，对 5-HT2A、5-HT2C、D2 和 α1-肾上腺素能受体具有中等亲和力。
T1336 Benztropine mesylate

Benzotropine mesylate,苯扎托品,Benzatropine mesylate,Benztropine methanesulfonate,甲磺酸苯扎托品

 Dopamine Receptor; AChR; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Benztropine mesylate (Benztropine methanesulfonate) 是一种可口服的中枢性抗胆碱能剂，用于帕金森氏病的研究。它是抗组胺剂，抑制多巴胺的吸收。它也是人 D2多巴胺受体的变构拮抗剂，具有抗癌症干细胞的作用。
T1097 Loratadine

氯雷他定,SCH 29851,Loratidine

 Influenza Virus; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Loratadine (SCH 29851) 是一种组胺 H1受体反向激动剂，IC50>32 μM。它抑制炎症介质的免疫释放，具有抗登革热病毒的活性。
T0211 Azelastine

Azelastina,Astelin,Azelastinum,氮卓斯汀

 SARS-CoV; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Azelastine (Azelastinum) 是一种选择性组胺 1 拮抗剂，可研究过敏性鼻炎、哮喘、糖尿病高脂血症和 SARS-CoV-2 。
T0903 Cinnarizine

Stugeron,桂利嗪,Cinarizine,Dimitronal,Stutgin

 Calcium Channel; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
Cinnarizine (Stugeron) 是一种哌嗪衍生物，具有组胺 H1 受体和钙通道阻断活性，具有扩张血管和止吐的特性，可促进脑血流，用于脑中风、创伤后脑症状和脑动脉硬化的研究。
T1575 Nizatidine

Axid,Acinon,尼扎替丁,Zanizal

 AChE; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Nizatidine (Acinon) 是一种竞争性和可逆的组胺 H2 受体拮抗剂，具有抗酸活性，可用于胃溃疡的研究。
T0089 Cetirizine dihydrochloride

盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Cetirizine dihydrochloride (UCB P071) 是羟嗪的羧化代谢物，是特异性口服有效的 H1 受体长效拮抗剂。它标记抗过敏特性，抑制过敏反应期间嗜酸性粒细胞趋化，可有效治疗过敏性鼻炎、确诊荨麻疹和花粉诱发的哮喘。

化合物

HTMT dimaleate
Cat.No: T22842
Synonym: HTMT马来酸氢盐,Histamine Trifluoromethyl Toluidide Dimaleate
Target: Histamine Receptor
Histamine H4 receptor antagonist-1
Cat.No: T38634
Synonym: Histamine H4 receptor antagonist-1
Target:
Clobenpropit dihydrobromide
Cat.No: T8439
Synonym:
Target: Apoptosis, Histamine Receptor
Chlorcyclizine
Cat.No: T9717
Synonym:
Target: HCV Protease, Histamine Receptor
(R)-(-)-α-Methylhistamine dihydrochloride
Cat.No: T24698
Synonym: HISTAMINE DIHYDROCHLORIDE R(-)-A-METHYL
Target:
OXOMEMAZINE
Cat.No: T9353
Synonym:
Target: AChR, Histamine Receptor
L 1935
Cat.No: T32436
Synonym: Compound l1935,L-1935,Histamine-liberator L 1935,L1935
Target:
Carebastine
Cat.No: T10680
Synonym:
Target: Histamine Receptor
Dimaprit dihydrochloride
Cat.No: T22724
Synonym:
Target: NOS, NO Synthase, Histamine Receptor
Thonzylamine
Cat.No: T4563
Synonym: neohetramine,松齐拉敏
Target: Histamine Receptor
JNJ-39758979
Cat.No: T11723L
Synonym:
Target: Histamine Receptor
Antazoline
Cat.No: T7477
Synonym:
Target: Others
Betahistine EP Impurity C
Cat.No: T4196
Synonym: NSC19005
Target: Others, Histamine Receptor
Bilastine
Cat.No: T4250
Synonym: 比拉斯汀,Bilaxten
Target: Histamine Receptor
Chlorphenoxamine
Cat.No: T7564
Synonym: Contristamine,氯苯沙明
Target: Histamine Receptor
Niaprazine
Cat.No: T36949
Synonym:
Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Ciproxifan maleate
Cat.No: T2004
Synonym: FUB 359 maleate,FUB 359
Target: Histamine Receptor
Lafutidine
Cat.No: T0081
Synonym: 拉呋替丁,FRG-8813
Target: 5-HT Receptor, Histamine Receptor
Astemizole
Cat.No: T1278
Synonym: Laridal,Histaminos,Paralergin,阿司咪唑
Target: Potassium Channel, Histamine Receptor
S 38093
Cat.No: T4099
Synonym: S38093,S-38093
Target: Histamine Receptor
Mebhydrolin
Cat.No: T7085
Synonym: Mebhydroline,美海屈林
Target: Histamine Receptor
VUF10460
Cat.No: T3963
Synonym:
Target: Histamine Receptor
Bromodiphenhydramine hydrochloride
Cat.No: T25180
Synonym:
Target: Others
Lodoxamide
Cat.No: T4566
Synonym: Lodoxamidum,洛草氨酸
Target: GPR, Histamine Receptor
LML134
Cat.No: T8514
Synonym: LML-134
Target: Histamine Receptor
Decloxizine
Cat.No: T22713
Synonym:
Target: Histamine Receptor
H4 Receptor antagonist 1
Cat.No: T5829
Synonym:
Target: Histamine Receptor
Acrivastine
Cat.No: T4551
Synonym: Acrivastin,阿伐斯汀,BW825C,Semprex
Target: Histamine Receptor
Metoprine
Cat.No: T8548
Synonym:
Target: Histone Methyltransferase, Antifolate, Histamine Receptor
JNJ-5207852
Cat.No: T7413
Synonym:
Target: Histamine Receptor
Tesmilifene fumarate
Cat.No: T22746
Synonym: DPPE fumarate
Target: Histamine Receptor
GSK189254A
Cat.No: TQ0066
Synonym: GSK189254
Target: Histamine Receptor
Pimethixene
Cat.No: T12489
Synonym: Calmixen,匹美噻吨,Pimetixene
Target: Dopamine Receptor, 5-HT Receptor, AChR, Histamine Receptor
Levocetirizine
Cat.No: T1469
Synonym: Levocetirizine HCl,左西替利嗪
Target: Histamine Receptor
Zotepine
Cat.No: T19680
Synonym:
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Hydroxyzine Pamoate
Cat.No: T0053
Synonym: Hydroxyzine embonate,双羟萘酸羟嗪,Bobsule,Equipose
Target: Histamine Receptor
Alcaftadine
Cat.No: T2533
Synonym: R89674,Lastacaft,阿卡他定
Target: Histamine Receptor
Metiamide
Cat.No: T7524
Synonym: 甲硫米特,SK&F 92058
Target: Histamine Receptor
Ebrotidine
Cat.No: T15195
Synonym: FI3542,乙溴替丁
Target: Histamine Receptor
Chlorprothixene
Cat.No: T0074
Synonym: Truxal,Clorprotixeno,Taractan,氯普噻吨
Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Histamine Receptor
Emedastine
Cat.No: T3979
Synonym: LY188695,依美斯汀,Emadine
Target: Histamine Receptor
Famotidine
Cat.No: T1627
Synonym: MK-208,法莫替丁
Target: Histamine Receptor
Dimenhydrinate
Cat.No: T0298
Synonym: 茶苯海明,Dramamine,Chloranautine,乘晕宁,Vomex A
Target: Histamine Receptor
Promethazine hydrochloride
Cat.No: T0445L
Synonym: 盐酸异丙嗪,Promethazine HCl,Phenergan
Target: Adrenergic Receptor, Histamine Receptor
Benztropine mesylate
Cat.No: T1336
Synonym: Benzotropine mesylate,苯扎托品,Benzatropine mesylate,Benztropine methanesulfonate,甲磺酸苯扎托品
Target: Dopamine Receptor, AChR, Histamine Receptor
Loratadine
Cat.No: T1097
Synonym: 氯雷他定,SCH 29851,Loratidine
Target: Influenza Virus, Histamine Receptor
Azelastine
Cat.No: T0211
Synonym: Azelastina,Astelin,Azelastinum,氮卓斯汀
Target: SARS-CoV, Histamine Receptor
Cinnarizine
Cat.No: T0903
Synonym: Stugeron,桂利嗪,Cinarizine,Dimitronal,Stutgin
Target: Calcium Channel, Histamine Receptor
Nizatidine
Cat.No: T1575
Synonym: Axid,Acinon,尼扎替丁,Zanizal
Target: AChE, Histamine Receptor
Cetirizine dihydrochloride
Cat.No: T0089
Synonym: 盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl
Target: Histamine Receptor
Cat. No. Product Name Target Signaling Pathways
T0965 Histamine

Ergamine,组胺

 5-HT Receptor; Endogenous Metabolite; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Histamine (Ergamine) 是通过组胺的酶促脱羧衍生的胺。它是一种强大的胃分泌兴奋剂、支气管平滑肌的收缩剂、血管扩张剂以及中枢作用的神经递质。
T6534 Histamine dihydrochloride

组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl

 Endogenous Metabolite; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Histamine dihydrochloride (Ceplene) 是 Histamine 的二盐酸形式。Histamine 是一种有机氮化合物，是一种强效的胃分泌兴奋剂，支气管平滑肌收缩剂，血管舒张剂，也是一种中枢作用的神经递质。
T6535 Histamine Phosphate

组胺磷酸盐,Histamine diphosphate,二磷酸组胺,Histamine acid phosphate

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Histamine Phosphate (Histamine acid phosphate) 是组胺受体的强激活剂和血管扩张神经剂，可激活一氧化氮合成酶。
T20712 Conessine

Conessinum,Wrightine,地麻素,Roquessine,Neriine,Konessin

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Conessine (Conessinum) 是一种具有抗疟活性的甾体生物碱，是高效选择性H3 受体拮抗剂，对于人、狗、豚鼠和大鼠 H3受体的Ki 分别为 5.4、6.0、5.7 和 25 nM。
T20884 Hydroxyzine

Hydroxyzine free base,羟嗪

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Hydroxyzine (Hydroxyzine free base) 是一种组胺 H1 受体拮抗剂，可有效治疗慢性荨麻疹、皮炎和组胺介导的瘙痒。它可作为止吐剂和镇静剂，缓解焦虑和紧张。
T4940 3-Methylhistamine dihydrochloride

Others; Endogenous Metabolite Metabolism; Others
3-Methylhistamine dihydrochloride 是一种组胺的降解产物，与免疫反应有关，并在接种过疫苗的小鼠中表现出上调作用。
TN6737 (25R)-Spirost-4-ene-3,12-dione

Others Others
(25R)-Spirost-4-ene-3,12-dione 是一种天然产物。
T0330 Diphenhydramine hydrochloride

盐酸苯海拉明,Diphenhydramine HCl,DPH

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Diphenhydramine hydrochloride (DPH) 是一种组胺 H1 拮抗剂，用作镇咳药和止吐药。它还用于治疗瘙痒和皮肤病、过敏反应、抗帕金森病、催眠药和普通感冒制剂的成分。
T2520 Desloratadine

Sch34117,地氯雷他定,NSC 675447

 Endogenous Metabolite; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Desloratadine (Sch34117) 是非镇静H1抗组胺药 Loratadine 的主要口服代谢物，可减少对支气管平滑肌、毛细血管和胃肠道平滑肌中 H1 受体的典型组胺能作用，包括血管舒张、支气管收缩、血管通透性增加、疼痛、瘙痒和胃肠道平滑肌的痉挛性收缩。它是一种选择性H1受体拮抗剂，具有抗过敏和抗炎活性。
T19443 N-Acetylhistamine

N-Omega-acetylhistamine,N-乙酰组胺

 Endogenous Metabolite; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
N-Acetylhistamine (N-Omega-acetylhistamine) 是组胺的代谢物。
TN1008 Psoralenoside

CaMK; Calcium Channel; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
Psoralenoside 是源于补骨脂中的苯并呋喃苷，具有抗肿瘤、抗菌、促进成骨细胞增殖和雌激素样活性。它对组胺 H1、钙调素和电压门控 l 型钙通道具有较高的亲和力。
T2848 Osthole

Osthol,NSC 31868,蛇床子素,Ostol

 Apoptosis; HBV; Parasite; Histamine Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Osthole (Osthol) 是一种天然抗组胺药替代试剂，可刺激成骨细胞增殖和分化。它可抑制组胺 H1受体活性，还可抑制细胞培养物中 HBV 的分泌。
T0783 Mianserin hydrochloride

Mianserin HCl,Org GB 94,盐酸米安色林,ORG GB-94 HCl

 Dopamine Receptor; 5-HT Receptor; Opioid Receptor; Adrenergic Receptor; Histamine Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Mianserin hydrochloride (Org GB 94) 是一种有抗抑郁活性的 H1 受体反向激动剂。
T20597 Alginic acid

Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine

 Apoptosis; Autophagy; Histamine Receptor Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Alginic acid (Snow acid algin G) 是一种从褐海藻中提取的天然多糖，具有抗过敏和抗炎活性。 Alginic acid 抑制组胺释放，可用于食品工业。
T8790 1-Methylhistamine dihydrochloride

Endogenous Metabolite Metabolism
1-Methylhistamine dihydrochloride 是组胺代谢物。
T13487 1-Methylhistamine

2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine

 Others Others
2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine is a histamine metabolite.
T19443L N-Acetylhistamine acetate

Endogenous Metabolite; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
N-Acetylhistamine acetate 是一种组胺代谢物。 它可用作过敏反应的组氨酸代谢的潜在生物标志物。
T4899 L-Histidinol dihydrochloride

Endogenous Metabolite Metabolism
L-Histidinol dihydrochloride 是内源性代谢产物的一种。
T0927 Butylparaben

Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate,尼泊金丁酯,对羟基苯甲酸丁酯

 Endogenous Metabolite; Antibacterial; Antibiotic Metabolism; Microbiology/Virology
Butylparaben (Butyl 4-hydroxybenzoate) 是一种标准化的化学过敏原，可增加组胺释放和细胞介导的免疫。
T0834 Ethylparaben

Ethyl 4-hydroxybenzoate,Ethyl parahydroxybenzoate,羟苯乙酯,尼泊金乙酯

 Antibacterial; Antifungal Microbiology/Virology
Ethylparaben (Ethyl parahydroxybenzoate) 是一种标准化的化学过敏原。 对羟基苯甲酸乙酯的生理作用是通过增加组胺释放和细胞介导免疫来实现的。
T5S1286 (+)-Columbianetin

二氢山芹醇,(S)-Columbianetin,Columbianetin

 Antifungal Microbiology/Virology
(+)-Columbianetin ((S)-Columbianetin) 是 Columbianetin 的异构体。其中Columbianetin 是一种植物抗毒素，与芹菜贮藏过程中对病原体的抗性有关，具有良好的抗真菌和抗炎作用。
TN1154 Nepetin

6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素

 Calcium Channel; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮，具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。
T1297 Eugenol

丁香酚,4-Allylguaiacol,Allylguaiacol,4-Allyl-2-methoxyphenol,Eugenic acid

 Apoptosis; Ferroptosis; Reactive Oxygen Species; Antibacterial; Parasite Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Eugenol (Allylguaiacol) 是一种从丁香中发现的精油，抑制脂质的过氧化，具有抗菌，驱虫和抗氧化活性。
T0908 Chlorquinaldol

5,7-Dichloro-8-hydroxy-2-methylquinoline,Chloquinan,氯喹那多

 Antibacterial; Antibiotic; Antifungal Microbiology/Virology
Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) 是一种抗菌剂, 有潜力研究局部皮肤病症和阴道感染。
T3429 Protopine

原阿片碱,Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine

 Reactive Oxygen Species; Platelet aggregation; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB; Others
Protopine (Fumarine) 是一种常存在于亚洲东北部的一些植物中的异喹啉类生物碱，常用于抗肿瘤、抗炎活性的研究。
TN1661 Ganoderic acid C2

灵芝酸 C2

 Reductase; Histamine Receptor; Immunology/Inflammation related Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Ganoderic acid C2 是分离自灵芝的一种三萜化合物， 具有潜在的抗肿瘤生物活性，以及抗组胺、抗衰老和细胞毒性作用。它对rat lens aldose reductase 具有很高的抑制活性，IC50为 3.8 µM。
T5S1889 Yunaconitine

Guayewuanine B,滇乌头碱

 Others Others
Yunaconitine (Guayewuanine B) 是一种乌头类生物碱，具有剧毒。
T2A2532 L-Histidine

Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine

 Mitochondrial Metabolism; Endogenous Metabolite Metabolism
L-Histidine (L-(-)-Histidine) 是人类生长和组织修复所需的一种半必需氨基酸(儿童应从食物中获得)。 L-Histidine 是线粒体谷氨酰胺转运的抑制剂。
T3728 Methyl Paraben

尼泊金甲酯,Methyl parahydroxybenzoate,Nipagin,对羟基苯甲酸甲酯,Methylparaben,Methyl 4-hydroxybenzoate,Methyl p-hydroxybenzoate

 Endogenous Metabolite; Antibacterial; Antibiotic Metabolism; Microbiology/Virology
Methyl Paraben (Nipagin) 是一种标准化的过敏原，是从云南铁杉中分离出来对羟基苯甲酸的甲酯。它是一种抗菌剂、防腐剂、调味剂。它的生理作用是通过增加组胺释放和细胞调控免疫实现的。
TN3483 Bakkenolide D

IL Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Bakkenolide D has anti-allergic effect, it and bakkenolide D demonstrates inhibitory effect on the trachea contraction induced by histamine in vitro, they have obvious anti-histamine activities.
TN2155 Rhodiocyanoside A

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Rhodiocyanoside A has antiallergic activity, it exhibits inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-DNP IgE and inhibits the PCA reaction in rats.
TN5279 Zeorin

ATPase; Calcium Channel; Antifection; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24-BSA, it shows potent inhibitory effect by 40% decrease of histamine release.
TN3699 Corchoionoside C

Antifection; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Corchoionoside C has antioxidant activity, shows strong scavenging activities on DPPH radical, it also shows weak antifungal activity. Corchoionosides A, B, and C inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.
TN5647 Confluentin

Confluentin has antimicrobial activity against the gram-positive bacteria.Confluentin significantly inhibits compound 48/80-induced histamine release from rat peritoneal mast cells. Confluentin also shows weak cytotoxicity against four human tumor cell li
TN1913 Marmin

Calcium Channel; Antifection; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine.
TN4392 Koaburaside

IL Receptor; TNF; Influenza Virus Apoptosis; Immunology/Inflammation; Microbiology/Virology
Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histamine release from mast cells.
TMA0627 Taxiresinol

TNF Apoptosis
Taxiresinol shows anticancer, antinociceptive, and antiallergic activities, it shows inhibitory activity on induced histamine release from the human basophilic cell line, KU812. Taxiresinol can protect the hepatocytes from apoptosis via an inhibition of TNF- alpha production by activated macrophages and a direct inhibition of apoptosis induced by TNF- alpha in D-GalN/LPS-treated mice.
TN3325 9-O-Feruloyl-5,5'-dimethoxylariciresinol

IL Receptor; TNF Apoptosis; Immunology/Inflammation
(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approxi
T80998 Thapsigargicin

Thapsigargicine
Thapsigargicin（Thapsigargicine）作为肥大细胞和白细胞的激活剂，能诱导大鼠腹膜肥大细胞及人嗜碱性粒细胞释放组胺，并提升完整人血小板中的细胞质游离钙水平。

天然产物

Histamine
Cat.No: T0965
Synonym: Ergamine,组胺
Target: 5-HT Receptor, Endogenous Metabolite, Histamine Receptor
Histamine dihydrochloride
Cat.No: T6534
Synonym: 组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl
Target: Endogenous Metabolite, Histamine Receptor
Histamine Phosphate
Cat.No: T6535
Synonym: 组胺磷酸盐,Histamine diphosphate,二磷酸组胺,Histamine acid phosphate
Target: Histamine Receptor
Conessine
Cat.No: T20712
Synonym: Conessinum,Wrightine,地麻素,Roquessine,Neriine,Konessin
Target: Histamine Receptor
Hydroxyzine
Cat.No: T20884
Synonym: Hydroxyzine free base,羟嗪
Target: Histamine Receptor
3-Methylhistamine dihydrochloride
Cat.No: T4940
Synonym:
Target: Others, Endogenous Metabolite
(25R)-Spirost-4-ene-3,12-dione
Cat.No: TN6737
Synonym:
Target: Others
Diphenhydramine hydrochloride
Cat.No: T0330
Synonym: 盐酸苯海拉明,Diphenhydramine HCl,DPH
Target: Histamine Receptor
Desloratadine
Cat.No: T2520
Synonym: Sch34117,地氯雷他定,NSC 675447
Target: Endogenous Metabolite, Histamine Receptor
N-Acetylhistamine
Cat.No: T19443
Synonym: N-Omega-acetylhistamine,N-乙酰组胺
Target: Endogenous Metabolite, Histamine Receptor
Psoralenoside
Cat.No: TN1008
Synonym:
Target: CaMK, Calcium Channel, Histamine Receptor
Osthole
Cat.No: T2848
Synonym: Osthol,NSC 31868,蛇床子素,Ostol
Target: Apoptosis, HBV, Parasite, Histamine Receptor
Mianserin hydrochloride
Cat.No: T0783
Synonym: Mianserin HCl,Org GB 94,盐酸米安色林,ORG GB-94 HCl
Target: Dopamine Receptor, 5-HT Receptor, Opioid Receptor, Adrenergic Receptor, Histamine Receptor
Alginic acid
Cat.No: T20597
Synonym: Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine
Target: Apoptosis, Autophagy, Histamine Receptor
1-Methylhistamine dihydrochloride
Cat.No: T8790
Synonym:
Target: Endogenous Metabolite
1-Methylhistamine
Cat.No: T13487
Synonym: 2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine
Target: Others
N-Acetylhistamine acetate
Cat.No: T19443L
Synonym:
Target: Endogenous Metabolite, Histamine Receptor
L-Histidinol dihydrochloride
Cat.No: T4899
Synonym:
Target: Endogenous Metabolite
Butylparaben
Cat.No: T0927
Synonym: Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate,尼泊金丁酯,对羟基苯甲酸丁酯
Target: Endogenous Metabolite, Antibacterial, Antibiotic
Ethylparaben
Cat.No: T0834
Synonym: Ethyl 4-hydroxybenzoate,Ethyl parahydroxybenzoate,羟苯乙酯,尼泊金乙酯
Target: Antibacterial, Antifungal
(+)-Columbianetin
Cat.No: T5S1286
Synonym: 二氢山芹醇,(S)-Columbianetin,Columbianetin
Target: Antifungal
Nepetin
Cat.No: TN1154
Synonym: 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素
Target: Calcium Channel, Histamine Receptor
Eugenol
Cat.No: T1297
Synonym: 丁香酚,4-Allylguaiacol,Allylguaiacol,4-Allyl-2-methoxyphenol,Eugenic acid
Target: Apoptosis, Ferroptosis, Reactive Oxygen Species, Antibacterial, Parasite
Chlorquinaldol
Cat.No: T0908
Synonym: 5,7-Dichloro-8-hydroxy-2-methylquinoline,Chloquinan,氯喹那多
Target: Antibacterial, Antibiotic, Antifungal
Protopine
Cat.No: T3429
Synonym: 原阿片碱,Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine
Target: Reactive Oxygen Species, Platelet aggregation, Histamine Receptor
Ganoderic acid C2
Cat.No: TN1661
Synonym: 灵芝酸 C2
Target: Reductase, Histamine Receptor, Immunology/Inflammation related
Yunaconitine
Cat.No: T5S1889
Synonym: Guayewuanine B,滇乌头碱
Target: Others
L-Histidine
Cat.No: T2A2532
Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine
Target: Mitochondrial Metabolism, Endogenous Metabolite
Methyl Paraben
Cat.No: T3728
Synonym: 尼泊金甲酯,Methyl parahydroxybenzoate,Nipagin,对羟基苯甲酸甲酯,Methylparaben,Methyl 4-hydroxybenzoate,Methyl p-hydroxybenzoate
Target: Endogenous Metabolite, Antibacterial, Antibiotic
Bakkenolide D
Cat.No: TN3483
Synonym:
Target: IL Receptor, Histamine Receptor
Rhodiocyanoside A
Cat.No: TN2155
Synonym:
Target: Histamine Receptor
Zeorin
Cat.No: TN5279
Synonym:
Target: ATPase, Calcium Channel, Antifection, Histamine Receptor
Corchoionoside C
Cat.No: TN3699
Synonym:
Target: Antifection, Histamine Receptor
Confluentin
Cat.No: TN5647
Synonym:
Target:
Marmin
Cat.No: TN1913
Synonym:
Target: Calcium Channel, Antifection, Histamine Receptor
Koaburaside
Cat.No: TN4392
Synonym:
Target: IL Receptor, TNF, Influenza Virus
Taxiresinol
Cat.No: TMA0627
Synonym:
Target: TNF
9-O-Feruloyl-5,5'-dimethoxylariciresinol
Cat.No: TN3325
Synonym:
Target: IL Receptor, TNF
Thapsigargicin
Cat.No: T80998
Synonym: Thapsigargicine
Target:
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