首页工具

登录

搜索结果

Search Results for " esc "

103

抑制剂 & 化合物

39

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T2431	ID-8 ID8	DYRK	Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
	ID-8 是 DYRK 抑制剂，长时间培养能够维持胚胎干细胞的自我更新。
T8005	Cardiogenol C hydrochloride 2-[[2-[(4-甲氧基苯基)氨基]-4-嘧啶基]氨基]乙醇盐酸盐,Cardiogenol C HCl,Cardiogenol C	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	Cardiogenol C hydrochloride (Cardiogenol C) 是一种细胞渗透性嘧啶诱导剂，能够促使 ESCs 分化为心肌细胞。在有限的可塑性范围内，它可以对已经沿袭的祖细胞类型产生心肌生成效应，是一种心肌生成试剂，在动物模型中可以用作细胞移植研究中提高心脏修复的工具。
T2161	Cardiogenol C	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	Cardiogenol C 是一种细胞渗透性嘧啶诱导剂，能够诱导 ESCs 分化为心肌细胞(EC50:100 nM)。在有限的可塑性范围内，它可以对已经沿袭的祖细胞类型产生心肌病，是一种心肌发生剂。
T20684	2',7'-Dichlorofluorescein diacetate Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,双氯荧光黄乙酸乙酯,DCFDA	Others	Others
	2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein) 是一种可渗透细胞的荧光探针，可用于检测一氧化氮和活性氧以及确定总体氧化应激的程度。
T11078	Deschloroclozapine	Serotonin Transporter	Neuroscience
	Deschloroclozapine 是氯氮平的代谢物，是一种高效毒蕈碱 DREADDs 激动剂。它可作为 PET 示踪剂，用于 DREADD 的影像学检查。它与 DREADD 受体亚型 hM3Dq 和 hM4Di 结合，Ki 分别为 6.3 和 4.2 nM。
T18990	Fluorescamine 荧光胺,Ro 20-7234	Others	Others
	Fluorescamine (Ro 20-7234) 是一种螺环化合物，其本身无荧光性质，但与初级胺反应后可形成荧光，因此可用于胺和肽的检测。
T18892	5(6)-Aminofluorescein 5(6)-氨基荧光素,Fluoresceinamine mixed isomers,5(6)-AFM	Others	Others
	5(6)-Aminofluorescein (5(6)-AFM) 是一种合成 5(6)-FITC 的前体。其中5(6)-FITC 是胺活性衍生物的荧光染料。
T4065	Fluorescein Sodium 荧光素钠,Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001	Others	Others
	Fluorescein Sodium (VST-1001) 是一种具有代表性的绿色荧光示踪剂，广泛用于医学、生物应用和肿瘤感染组织的示踪剂，也可作为实用绿色荧光探针的支架。
T36953	Naphthofluorescein Naphthafluorescein	HIF	Angiogenesis; Chromatin/Epigenetic
	Naphthofluorescein （Naphthafluorescein）是一种 Mint3 抑制剂，具有潜在的抗肿瘤和抗炎活性，抑制 HIF-1 和 Mint3 之间的相互作用，抑制 Mint3 依赖性 HIF-1 活性，抑制癌细胞和巨噬细胞的糖酵解活动，同时未显示出明显的体外细胞毒性和体内副作用。Naphthofluorescein 也是一种荧光 pH 敏感探针，可用于功能性切伦科夫成像。
T1392	Fluorescein Solvent Yellow 94,Resorcinol phthalein,荧光素,Yellow fluorescein	Others	Others
	Fluorescein (Solvent Yellow 94) 是一种合成的有机光敏染料化合物，是一种荧光示踪剂，可以用于医学和生物学以及肿瘤感染的组织。
T18893	5(6)-Carboxyfluorescein 5(6)-羧基荧光素,5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM	Others	Others
	5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) 是一种胺反应性 pH 敏感的绿色荧光标记物，能够标记蛋白质、多肽和氨基酸，可用于体内实验检测肿瘤位置。
T18900	6-Aminofluorescein 6-AF,6-氨基荧光素	Others	Others
	6-Aminofluorescein (6-AF) 是新型的荧光标记物。
T18991	Fluorescein-5-maleimide N-(5-Fluoresceinyl)maleimide,荧光素-5-马来酰亚胺	Others	Others
	Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) 是硫醇反应荧光染料 (λex=494 nm，λem=519 nm)，可用于将荧光素与蛋白质缀合。
T6170	Elesclomol 伊利司莫,STA-4783	Apoptosis; HSP; Reactive Oxygen Species	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB
	Elesclomol (STA-4783) 是一种氧化应激诱导剂，也是一种高度亲脂性的铜离子载体。Elesclomol 可以诱导肿瘤细胞凋亡，用于铜死亡相关研究。Elesclomol 还可以抑制 FDX1 介导的 Fe-S 簇生物合成。
T18976	Dihydrofluorescein diacetate 二氢荧光素二乙酸酯,Diacetyldihydrofluorescein	Others	Others
	Dihydrofluorescein diacetate (Diacetyldihydrofluorescein) 是一种荧光探针，用于测量无细胞系统和细胞模型中的氧化应激。
T18992	Fluorescein Biotin Fluoresceinbiotin	Autophagy	Autophagy
	Fluorescein Biotin 是一种可替代生物素的荧光染料，通过荧光或吸光度来检测和量化生物素结合位点。Fluorescein Biotin 与抗生物素蛋白 (avidin) 或链霉亲和素 (streptavidin) 结合会发生荧光淬灭现象。
T18889	5-Aminofluorescein 5-氨基荧光素,5-AF	Others	Others
	5-Aminofluorescein (5-AF) (5-AF) is a covalently-bound fluorescence marker conjugated with human serum albumin. It exhibits an excitation wavelength of 490 nm and an emission wavelength of 515 nm.
T22304	Desciclovir BW A515U,地昔洛韦,6-Deoxyacyclovir,DCV	Antifection	Microbiology/Virology
	Desciclovir (DCV) 是抗疱疹药物阿昔洛韦的前药，口服有活性，在体内被黄嘌呤氧化酶转化成为阿昔洛韦。
T19323	Fluorescein diacetate 荧光素二乙酸酯,3,6-Diacetoxyfluoran,Di-O-acetylfluorescein	Others	Others
	Fluorescein diacetate (Di-O-acetylfluorescein) 是一种人谷胱甘肽硫转移酶 Pi 的荧光底物，是一种细胞渗透性的酯酶底物。
T6493	Escitalopram Oxalate 草酸右旋西酞普兰,依他普仑草酸盐,Cipralex,(S)-(+)Citalopram oxalate	Others; 5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience; Others
	Escitalopram Oxalate ((S)-(+)Citalopram oxalate) 是一种外消旋 Citalopram 的 S-对映体，是一种选择性 5-羟色胺再摄取抑制剂，Ki=0.89 nM，比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性，是一种研究抑郁症的抗抑郁药。
T65146	Esculin hydrate(2:3)
	7-Hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one hydrate(2:3) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T65146。
T15295	Fluorescein-PEG6-bis-NHS ester	Others	Others
	Fluorescein-PEG6-bis-NHS ester is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T82892	Bevonescein ALM-488
	Bevonescein（ALM-488）作为一种荧光标记肽，专门用于结合人类神经元或神经组织。Bevonescein常作为诊断成像剂使用。
T77046	Ivonescimab
	Ivonescimab (AK112) 是一种PD-1/VEGF 双特异性抗体。Ivonescimab 可用于癌症研究。
T16191	N-(Azido-PEG3)-N-Fluorescein-PEG3-acid	Others	Others
	N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEGylated PROTAC linker incorporating azide, fluorescein, and carboxylic acid functional groups.
T78387	5-Dodecanoylaminofluorescein
	5-Dodecanoylaminofluorescein为亲脂性荧光探针，属于游离脂肪酸的荧光素衍生物。该探针应用于膜流动性分析与洗涤剂临界胶束浓度测定，并可用于制备药物递送用的疏水性纳米球。
T76490	Fluorescent HIV Substrate
	FluorescentHIVSubstrate 是 HIV 底物。
T40400	Enhanced Green Fluorescent Protein (EGFP) (200-208)
	Enhanced Green Fluorescent Protein (EGFP) (200-208) is a reporter protein obtained from Aequorea Victoria jellyfish. EGFP is widely used as a marker gene product due to its strong fluorescence properties, making it easily detectable.
T76469	Esculentin 1A
	Esculentin 1A 是一种青蛙皮肤来源的抗菌肽(AMP)，具有强大的体外抗假单胞菌活性。
T78347	Serratia marcescens nuclease
	Serratia marcescens nuclease，为一种非特异性核酸酶，因具备强大消化DNA与RNA活性，应用范围广泛。
T36418	O-Desmethyl-N-deschlorobenzoyl Indomethacin
	O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin .1It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase.2It has also been used in the synthesis of prostaglandin D2receptor antagonists.3 1.Evans, M.A., Papazafiratou, C., Bhat, R., et al.Indomethacin metabolism ...
T16183	N-(Azido-PEG2)-N-Fluorescein-PEG3-acid	Others	Others
	N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a polyethylene glycol (PEG)-derived PROTAC linker specifically designed for the synthesis of PROTACs[1].
T19542	(±)-H3RESCA-TFP (±)-H3L28	Others	Others
	(±)-H3RESCA-TFP is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA).
T124811	Lushanrubescensin H
	Lushanrubescensin H 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124811。
T34291	Rescinnamidine Reserpic acid
	Rescinnamidine is an alkaloid.
T17944	Fluorescein-PEG5-NHS ester	Others	Others
	Fluorescein-PEG5-NHS ester, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].
T72899	Glabrescone C
	Glabrescone C 具有显著的抗炎效果，其作用机制是直接针对IKKα/β。
T36304	Fluorescein-NAD+
	Fluoroscein NAD+ is a substrate for ADP-ribosylation, providing a convenient non-isotopic alternative to radiolabelled NAD for use in PARP assays. Allows direct measurement of NAD-dependent enzymes, such as PARP, by fluorescence microscopy. This product is a replacement for R&D Systems product 4673-500-01 81 μg is supplied as 250 μl of a 0.25 mM solution in water.
T15290	Fluorescein-DBCO	Others	Others
	Fluorescein-DBCO is a non-cleavable linker employed for synthesizing antibody-drug conjugates (ADCs) [1].
T123995	Hebeirubescensin L
	Hebeirubescensin L 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T123995，CAS号为 887333-34-8。
T78590	Dibenzylfluorescein DBF
	Dibenzylfluorescein（DBF）是一款荧光探针，作为细胞色素P450（CYP）亚型，包括CYP3A4、CYP2C8、CYP2C9、CYP2C19和CYP19的特异性底物，常在Km值0.87-1.9 µM（Ex=485nm，Em=535nm）范围内应用。该探针主要用于监测药物或疾病导致的CYP催化活性变化。
T4432	5-Carboxyfluorescein diacetate N-succinimidyl ester

T38256	Pentafluorobenzenesulfonyl fluorescein	Others	Others
	Pentafluorobenzenesulfonyl fluorescein 本身无荧光，但在磺酰基键被 H2O2 过水解时会发荧光。Pentafluorobenzenesulfonyl fluorescein 常被当作选择性 H2O2 传感器，可用于检测细胞中的 H2O2 含量。
T82389	Fluorescein octadecyl ester
	Fluorescein octadecyl ester为亲脂性荧光试剂，适用于固定于塑化PVC膜中。该试剂能可逆地识别酒精分子，应用于测定酒精饮料中的乙醇浓度。此外，Fluorescein octadecyl ester亦可作为光极膜的受体，用于苦味酸的测定。
T15291	Fluorescein-PEG3-amine	Others	Others
	Fluorescein-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T39546	Fluorescein tyramide
	Fluorescein tyramide is a widely utilized green fluorescent reagent (λ abs : 494 nm; λ em : 517 nm), primarily employed for tyramide signal amplification (TSA) in low-abundance IHC, ICC, in situ hybridization (FISH), and flow cytometry (FCM) applications.
T34290	Rescimetol WHO-4939,WHO4939,WHO 4939
	Rescimetol is a biochemical.
T17708	Carboxyfluorescein-PEG12-NHS	Others	Others
	Carboxyfluorescein-PEG12-NHS is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker. It serves as a crucial component in synthesizing PROTACs, a class of molecules designed for targeted protein degradation[1].
T125361	Eschweilenol C
	Eschweilenol C 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125361。
T74292	Fluorescent DOTAP
	Fluorescent DOTAP 是一种阳离子脂质，可用于研究核酸和蛋白质传递。

化合物

Cat.No: T2431

Synonym: ID8

Target: DYRK

Cardiogenol C hydrochloride

Cat.No: T8005

Synonym: 2-[[2-[(4-甲氧基苯基)氨基]-4-嘧啶基]氨基]乙醇盐酸盐,Cardiogenol C HCl,Cardiogenol C

Target: Wnt/beta-catenin

Cat.No: T2161

Target: Wnt/beta-catenin

2',7'-Dichlorofluorescein diacetate

Cat.No: T20684

Synonym: Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,双氯荧光黄乙酸乙酯,DCFDA

Target: Others

Deschloroclozapine

Cat.No: T11078

Target: Serotonin Transporter

Cat.No: T18990

Synonym: 荧光胺,Ro 20-7234

Target: Others

5(6)-Aminofluorescein

Cat.No: T18892

Synonym: 5(6)-氨基荧光素,Fluoresceinamine mixed isomers,5(6)-AFM

Target: Others

Fluorescein Sodium

Cat.No: T4065

Synonym: 荧光素钠,Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001

Target: Others

Naphthofluorescein

Cat.No: T36953

Synonym: Naphthafluorescein

Target: HIF

Cat.No: T1392

Synonym: Solvent Yellow 94,Resorcinol phthalein,荧光素,Yellow fluorescein

Target: Others

5(6)-Carboxyfluorescein

Cat.No: T18893

Synonym: 5(6)-羧基荧光素,5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM

Target: Others

6-Aminofluorescein

Cat.No: T18900

Synonym: 6-AF,6-氨基荧光素

Target: Others

Fluorescein-5-maleimide

Cat.No: T18991

Synonym: N-(5-Fluoresceinyl)maleimide,荧光素-5-马来酰亚胺

Target: Others

Cat.No: T6170

Synonym: 伊利司莫,STA-4783

Target: Apoptosis, HSP, Reactive Oxygen Species

Dihydrofluorescein diacetate

Cat.No: T18976

Synonym: 二氢荧光素二乙酸酯,Diacetyldihydrofluorescein

Target: Others

Fluorescein Biotin

Cat.No: T18992

Synonym: Fluoresceinbiotin

Target: Autophagy

5-Aminofluorescein

Cat.No: T18889

Synonym: 5-氨基荧光素,5-AF

Target: Others

Cat.No: T22304

Synonym: BW A515U,地昔洛韦,6-Deoxyacyclovir,DCV

Target: Antifection

Fluorescein diacetate

Cat.No: T19323

Synonym: 荧光素二乙酸酯,3,6-Diacetoxyfluoran,Di-O-acetylfluorescein

Target: Others

Escitalopram Oxalate

Cat.No: T6493

Synonym: 草酸右旋西酞普兰,依他普仑草酸盐,Cipralex,(S)-(+)Citalopram oxalate

Target: Others, 5-HT Receptor, Serotonin Transporter

Esculin hydrate(2:3)

Cat.No: T65146

Fluorescein-PEG6-bis-NHS ester

Cat.No: T15295

Target: Others

Cat.No: T82892

Synonym: ALM-488

Cat.No: T77046

N-(Azido-PEG3)-N-Fluorescein-PEG3-acid

Cat.No: T16191

Target: Others

5-Dodecanoylaminofluorescein

Cat.No: T78387

Fluorescent HIV Substrate

Cat.No: T76490

Enhanced Green Fluorescent Protein (EGFP) (200-208)

Cat.No: T40400

Esculentin 1A

Cat.No: T76469

Serratia marcescens nuclease

Cat.No: T78347

O-Desmethyl-N-deschlorobenzoyl Indomethacin

Cat.No: T36418

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid

Cat.No: T16183

Target: Others

(±)-H3RESCA-TFP

Cat.No: T19542

Synonym: (±)-H3L28

Target: Others

Lushanrubescensin H

Cat.No: T124811

Cat.No: T34291

Synonym: Reserpic acid

Fluorescein-PEG5-NHS ester

Cat.No: T17944

Target: Others

Cat.No: T72899

Fluorescein-NAD+

Cat.No: T36304

Fluorescein-DBCO

Cat.No: T15290

Target: Others

Hebeirubescensin L

Cat.No: T123995

Dibenzylfluorescein

Cat.No: T78590

Synonym: DBF

5-Carboxyfluorescein diacetate N-succinimidyl ester

Cat.No: T4432

Pentafluorobenzenesulfonyl fluorescein

Cat.No: T38256

Target: Others

Fluorescein octadecyl ester

Cat.No: T82389

Fluorescein-PEG3-amine

Cat.No: T15291

Target: Others

Fluorescein tyramide

Cat.No: T39546

Cat.No: T34290

Synonym: WHO-4939,WHO4939,WHO 4939

Carboxyfluorescein-PEG12-NHS

Cat.No: T17708

Target: Others

Eschweilenol C

Cat.No: T125361

Fluorescent DOTAP

Cat.No: T74292

Cat. No.	Product Name	Target	Signaling Pathways
T0185	Escitalopram Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram	Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Escitalopram (Seroplex) 是一种外消旋 Citalopram 的 S-对映体，是一种选择性 5-羟色胺再摄取抑制剂，Ki=0.89 nM，比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性，是一种研究抑郁症的抗抑郁药。
T8846	beta-Escin B-escin,AESCINE,beta-七叶素	Immunology/Inflammation related	Immunology/Inflammation
	beta-Escin 是七叶树种子的主要活性成分。它可抑制碱性成纤维细胞生长因子所诱导的增殖、迁移、管形成以及体内 CAM 血管生成。它具有研究抗血管生成作用的分子机制的潜力。
TJS0338	4-Methylesculetin 4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭	Antioxidant; Glutathione Peroxidase	Metabolism; oxidation-reduction
	4-Methylesculetin (Methylesculetin) 是口服具有活力的天然香豆素衍生物，有抗氧化、抗炎特性。它可抑制myeloperoxidase 的特性，抑制 IL-6 的水平
T7508	N-Acetylputrescine hydrochloride	Endogenous Metabolite	Metabolism
	N-Acetylputrescine hydrochloride 是腐胺衍生物。
TN2107	Protoescigenin	Others	Others
	Protoescigenin 来自七叶树皂甙混合物，可用作用于选择性保护的探索性化学的底物。
T0278	Escin 七叶皂苷,七叶皂素,Aescin	Apoptosis; Others	Apoptosis; Others
	Escin (Aescin) 是从七叶树种子中分离得到的一种三萜皂苷，有血管保护、抗炎、抗水肿和抗伤害作用。
T5S1389	Escin IB 七叶皂苷B,七叶皂苷 IB	5-HT Receptor; NO Synthase	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Escin IB 是一种皂苷，分离自马栗子种子的皮和胚乳中，能够抑制 pancreatic lipase 的活性。
T4S1387	Isoescin IA 七叶皂苷C,异七叶皂苷 IA	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Isoescin IA 是一种从七叶树种子中分离出来的三萜皂苷。它具有抗HIV-1蛋白酶活性。
T3877	Esculentoside A	NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Esculentoside A 是一种三萜皂苷，从商陆根部分离得到。它在具有抗炎活性，对环氧合酶-2 具有选择性抑制活性。它通过抑制NF-κB 和丝裂原活化蛋白激酶信号通路抑制 LPS 诱导的急性肺损伤中的炎症反应。
T8918	Feruloylputrescine	Others	Others
	Feruloylputrescine 是一种天然产物。
T3027	Sodium Aescinate Escin sodium salt,七叶皂苷钠	HIF	Angiogenesis; Chromatin/Epigenetic
	Sodium Aescinate (Escin sodium salt) 是一种三萜皂苷，来源于Aesculus hippocastanum 的种子，具有抗炎、抗氧化作用。它可以通过靶向 CARMA3/NF-κB 途径，抑制抑制肝癌生长。
T2885	Esculin 秦皮甲素,马栗树皮甙,Aesculin	Antiviral; p38 MAPK; Antibacterial	Immunology/Inflammation; MAPK; Microbiology/Virology
	Esculin (Aesculin) 是灰树皮的荧光香豆素葡萄糖苷，可通过 MAPK 信号通路改善实验性糖尿病肾病的认知障碍，并发挥抗氧化应激和抗炎作用。
T3S1641	Esculentoside H	TNF; NF-κB; JNK	Apoptosis; MAPK; NF-κB
	Esculentoside H 是一种皂苷，分离自多年生植物 Phytolacca esculent 的根提取物中，具有抗肿瘤作用。它的机制与 TNF 释放能力有关。它能够阻断 JNK1/2和 NF-κB 信号介导的基质金属蛋白酶-9 (MMP-9) 表达，抑制结肠癌细胞迁移。
T41078	Lipopolysaccharides, Escherichiacoli (11C) LPS E. coli O55:B5,Lipopolysaccharide, E. coli O111:B4	Others	Others
	Lipopolysaccharides, Escherichiacoli (11C) (LPS E. coli O55:B5)是革兰阴性菌外膜的大分子成分，由脂质a、寡糖核心和o -特异性多糖(O-antigen) 3个区域组成。
TN1777	Isoescin IB	Others	Others
	Isoescin IB 是 Escin IB 的异构体，两者是 Escin 中的主要活性成分。
T4S1383	Escin IA Aescin IA,Escin IA;Aescin IA,Escin IA	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Escin IA (Escin IA;Aescin IA);Aescin IA 是从马蹄中七叶树分离出的一种三萜皂苷，抑制HIV-1蛋白酶，IC50值为 35 μM。它具有抗 TNBC 转移活性，其作用机制涉及通过下调 LOXL2 表达抑制上皮-间质转化过程。
T2798	Esculetin 秦皮乙素,二羟基香豆素,Aesculetin,Cichorigenin	Lipoxygenase; Akt; PI3K	Cytoskeletal Signaling; Metabolism; PI3K/Akt/mTOR signaling
	Esculetin (Cichorigenin) 是主要提取自水曲柳的树皮中的活性成分。它能够抑制PI3K/Akt 途径，阻碍血小板衍生生长因子诱导的气道平滑肌细胞表型转换。它具有抗氧化，抗炎和抗肿瘤的活性。
T80344	Aeschna defensin
	Aeschna defensing是源自蜻蜓水生幼虫血淋巴的抗菌肽，对革兰氏阳性菌具有显著活性。
TN1967	N-Caffeoylputrescine,(E)- 咖啡酰丁二胺,(E)-N-Caffeoylputrescine	Others	Others
	N-Caffeoylputrescine has antioxidant activity.
T82974	Arborescosidic acid Deacetylalpinoside
	Arborescosidic acid (Deacetylalpinoside)为一环烯醚萜糖苷化合物，具羧酸官能团，源自Veronica beccabunga (brooklime)。
T79996	N,N′-Diferuloylputrescine	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	N,N′-Diferuloylputrescine 作为pigmentation的抑制剂，有效减少了57%的色素沉着，并显著降低了MITF蛋白水平。同时，该化合物对活性氧表现出强大的抗氧化活性。
TN4014	Esculentoside B	Antifection	Microbiology/Virology
	Phytolaccoside B(Esculentoside B) is an antifungal monodesmoside triterpenoid glycoside, it has potent inhibitory activity against agrobacterial plant transformation.
TN1358	Escin IIa 七叶皂苷C,Aescin IIA	Others	Others
	Aescin IIA is a natural product
TN6442	Esculentoside C
	Esculentoside C exerts proinflammatory effects synergistically, it can induce inflammatory stimulation.
TN2217	Sophoflavescenol 槐苦参醇,槐黄醇	Others; Beta-Secretase; BACE; PDE; AChR; AChE	Metabolism; Neuroscience; Others
	Sophoflavescenol 是异戊烯基黄酮类化合物，能够抑制PDE5的活性，IC50=0.013 μM。它也抑制 RLAR，HRAR，BACE1，AChE 和 BChE，IC50值分别为 0.30 µM，0.17 µM，10.98 µM，8.37 µM 和 8.21 µM。
TN1623	Escin IIB	Others; NOS	Immunology/Inflammation; Others
	Escin IIB has positive effects on acute inflammation in animals, it can inhibit the induced by serotonin in rats, the hind paw edema induced by carrageenin, and the scratching behavior induced by compound 48/80 in mice.
T82036	Isoescin Ie
	Isoescin Ie，一种Aescine的衍生物，系由Aesculi Semen提取物中分离得到。
TN4013	Esculentic acid	IL Receptor; TNF; COX	Apoptosis; Immunology/Inflammation; Neuroscience
	Esculentic acid has anti-inflammatory effect, it has protective effects against LPS-induced endotoxic shock may be mediated, at least in part, by regulation the release of inflammatory cytokines and mediators, and protein expression of COX-2 in mice.
TN6024	N-p-Coumaroyl-N'-caffeoylputrescine
	N-p-Coumaroyl-N'-caffeoylputrescine是一种天然产物，属于蔷薇科白鹃梅属，其产品编号为 TN6024，CAS号为 1138156-77-0。N-p-Coumaroyl-N'-caffeoylputrescine可用作对照参考。
T39080	Escin Ie
	Escin Ie is a derivative of Aescine in Aesculi Semen extract.
T80631	Esculin sesquihydrate	p38 MAPK	MAPK
	Esculin sesquihydrate为荧光香豆素葡萄糖苷类化合物，源自灰树皮有效成分。该化合物可经MAPK信号通路改善实验性糖尿病肾病(DN)的认知障碍，并具有抗氧化应激及抗炎效应。
TN6212	Aesculioside D
	Aesculioside D 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6212，CAS号为 254896-66-7。
T32979	Lushanrubescensin E
	Lushanrubescensin E is a bioactive chemical.
TN6222	Isoaesculioside D
	Isoaesculioside D 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6222，CAS号为 1184581-59-6。
TN6223	Aesculioside C
	Aesculioside C 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6223，CAS号为 254896-65-6。
TN6443	Esculentoside T
	Esculentoside T 可分离自商陆根部。
TN4186	Hebeirubescensin H	Others	Others
	Hebeirubescensin H is a natural product from Isodon parvifolius.
T19911	Rescinnamine Anaprel,Apoterin S,Apoterin
	Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug.
T81636	N-trans-Feruloylputrescine
	N-trans-Feruloylputrescine为一生物碱，可从Magnolia officinalis中分离。

天然产物

Cat.No: T0185

Synonym: Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor

Cat.No: T8846

Synonym: B-escin,AESCINE,beta-七叶素

Target: Immunology/Inflammation related

4-Methylesculetin

Cat.No: TJS0338

Synonym: 4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭

Target: Antioxidant, Glutathione Peroxidase

N-Acetylputrescine hydrochloride

Cat.No: T7508

Target: Endogenous Metabolite

Cat.No: TN2107

Target: Others

Cat.No: T0278

Synonym: 七叶皂苷,七叶皂素,Aescin

Target: Apoptosis, Others

Cat.No: T5S1389

Synonym: 七叶皂苷B,七叶皂苷 IB

Target: 5-HT Receptor, NO Synthase

Cat.No: T4S1387

Synonym: 七叶皂苷C,异七叶皂苷 IA

Target: HIV Protease

Esculentoside A

Cat.No: T3877

Target: NF-κB, COX

Feruloylputrescine

Cat.No: T8918

Target: Others

Sodium Aescinate

Cat.No: T3027

Synonym: Escin sodium salt,七叶皂苷钠

Target: HIF

Cat.No: T2885

Synonym: 秦皮甲素,马栗树皮甙,Aesculin

Target: Antiviral, p38 MAPK, Antibacterial

Esculentoside H

Cat.No: T3S1641

Target: TNF, NF-κB, JNK

Lipopolysaccharides, Escherichiacoli (11C)

Cat.No: T41078

Synonym: LPS E. coli O55:B5,Lipopolysaccharide, E. coli O111:B4

Target: Others

Cat.No: TN1777

Target: Others

Cat.No: T4S1383

Synonym: Aescin IA,Escin IA;Aescin IA,Escin IA

Target: HIV Protease

Cat.No: T2798

Synonym: 秦皮乙素,二羟基香豆素,Aesculetin,Cichorigenin

Target: Lipoxygenase, Akt, PI3K

Aeschna defensin

Cat.No: T80344

N-Caffeoylputrescine,(E)-

Cat.No: TN1967

Synonym: 咖啡酰丁二胺,(E)-N-Caffeoylputrescine

Target: Others

Arborescosidic acid

Cat.No: T82974

Synonym: Deacetylalpinoside

N,N′-Diferuloylputrescine

Cat.No: T79996

Target: Melanocortin Receptor

Esculentoside B

Cat.No: TN4014

Target: Antifection

Cat.No: TN1358

Synonym: 七叶皂苷C,Aescin IIA

Target: Others

Esculentoside C

Cat.No: TN6442

Sophoflavescenol

Cat.No: TN2217

Synonym: 槐苦参醇,槐黄醇

Target: Others, Beta-Secretase, BACE, PDE, AChR, AChE

Cat.No: TN1623

Target: Others, NOS

Cat.No: T82036

Esculentic acid

Cat.No: TN4013

Target: IL Receptor, TNF, COX

N-p-Coumaroyl-N'-caffeoylputrescine

Cat.No: TN6024

Cat.No: T39080

Esculin sesquihydrate

Cat.No: T80631

Target: p38 MAPK

Cat.No: TN6212

Lushanrubescensin E

Cat.No: T32979

Isoaesculioside D

Cat.No: TN6222

Cat.No: TN6223

Esculentoside T

Cat.No: TN6443

Hebeirubescensin H

Cat.No: TN4186

Target: Others

Cat.No: T19911

Synonym: Anaprel,Apoterin S,Apoterin

N-trans-Feruloylputrescine

Cat.No: T81636

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼