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45

抑制剂 & 化合物

6

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Cat. No. Product Name Target Signaling Pathways
T7545 6-Aminonicotinamide

Others Others
6-Aminonicotinamide 是一种竞争性 NADP+依赖性酶,是一种烟酰胺抗代谢药,葡萄糖 6-磷酸脱氢酶抑制剂 (Ki=0.46 μM)。 它干扰糖酵解,导致 ATP 耗竭,并与 DNA 交联化学疗法药物,如Cisplatin,协同杀死癌细胞。
T9919 Alemtuzumab

Others Others
Alemtuzumab 是人源化抗 CD52单克隆抗体, CD52是一种表达于大多数淋巴细胞以及少数的髓细胞类型的糖蛋白。Alemtuzumab 与能够特异性作用于 CD52 抗原,诱导淋巴细胞深度耗竭,恢复具有调节表型的 T 细胞和 B 细胞。
T38369 CAY10678

Prostaglandin Receptor; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; GPCR/G Protein; Immunology/Inflammation
CAY10678 是一种 mPGES-1抑制剂,抑制 PD-1。CAY10678 可减少胶原沉积和T细胞耗竭,可用于研究黑色素瘤。
T38709 PFM39

Others Others
PFM39 是一种选择性 MRE11 核酸外切酶抑制剂,是 Mirin 类似物,可延长有丝分裂。PFM39 抑制 HR,可缓解由 EXO1/BLM 耗竭引起的修复缺陷。
T16680 PTC-028

Apoptosis; BMI-1 Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
PTC-028 是一种口服有效的干细胞因子 BMI-1的抑制剂,可下调 BMI-1,诱导 caspase 介导的细胞凋亡。它选择性地抑制癌细胞,可用于治疗卵巢癌。
T14283 amyloid P-IN-1

Beta Amyloid Neuroscience
amyloid P-IN-1 可用于研究血清淀粉样蛋白 P 成分耗尽的疾病,例如阿尔茨海默病、淀粉样变性、骨关节炎和 2 型糖尿病。
T13810 Palmitoylcarnitine chloride

Palmitoyl DL-carnitine chloride

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) 是一种线粒体脂肪酸氧化中间体,可介导脂质内心脏保护。Palmitoylcarnitine chloride 通过消耗谷胱甘肽来消除结直肠癌细胞的存活,诱导癌细胞死亡,调节蛋白激酶 C βII 与其受体 RACK1 之间的相互作用。
T5523 Imidazole ketone erastin

IKE

Ferroptosis Apoptosis
Imidazole ketone erastin (IKE) 是一种铁死亡诱导剂,对 system Xc-胱氨酸/谷氨酸转运蛋白具有抑制作用。Imidazole ketone erastin 具有抗肿瘤活性,可以诱导谷胱甘肽耗竭和脂质过氧化。
T7295 Miridesap

Ro63-8695,CPHPC,GSK2315698

Others Others
Miridesap (GSK2315698) 是一种血清淀粉样蛋白 P 组分 (SAP) 的配体,能够利用肝脏清除导致循环 SAP 的快速消耗。 它也可以明显减少脑脊液和内脏淀粉样蛋白沉积物中的 SAP。
T10497 Benralizumab

BIW-8405,MEDI-563

Apoptosis; IL Receptor; Interleukin Apoptosis; Immunology/Inflammation
Benralizumab (MEDI-563) 是一种靶向白介素 5 受体 α (IL-5Rα) 单克隆抗体,通过增强抗体依赖性细胞介导的细胞毒性促使嗜酸性粒细胞快速进行反应。Benralizumab 可用于严重的嗜酸性哮喘,可用于预防慢性阻塞性肺病加重。
T6543 Indoximod

NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan,吲哚莫德

Indoleamine 2,3-Dioxygenase (IDO) Metabolism
Indoximod (Indoximod (NLG-8189)) 是一种具有口服具有活力的吲哚胺2,3-双加氧酶(IDO) 途径抑制剂。它在调节 mTOR 中充当 Trp 模拟物。它是一种可用于癌症研究的免疫代谢佐剂。
T68095 Losulazine

Dopamine Receptor; Norepinephrine GPCR/G Protein; Neuroscience
Losulazine 是一种新型的降压化合物。其确切的作用机制尚未确定,但其降压作用取决于完整的、功能性交感神经系统的存在。
T76830 Teneliximab

Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819

TNF Apoptosis
Teneliximab (Chi220) 是一种嵌合的单克隆抗体,也是一种肿瘤坏死因子受体超家族成员5(CD40)抑制剂,可阻断CD40-CD40L 的相互作用。Teneliximab 通过CD40 和外周B细胞损耗发挥部分激动剂活性,可用于研究器官移植排斥和类风湿关节炎。
T0893 Tinidazole

替硝唑,CP12574

Antibacterial; Antibiotic Microbiology/Virology
Tinidazole (CP12574) 是一种对厌氧菌和原生动物具有选择性抗菌活性的 5-硝基咪唑,是一种具有口服活性的抗菌剂。
T38034 MAO-IN-M30 dihydrochloride

M 30 dihydrochloride

Monoamine Oxidase Neuroscience
MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) 是一种口服活性,可通过血脑屏障的,脑选择性不可逆 MAO-A (IC50=37 nM) 和 MAO-B (IC50=57 nM) 抑制剂。MAO-IN-M30 dihydrochloride 是有效的铁螯合剂、自由基清除剂。MAO-IN-M30 dihydrochloride 对 Dexamethasone 诱导的脑细胞凋亡具有神经保护作用。MAO-IN-M30 dihydrochloride 在 MPTP 和 lactacystin 帕金森病模型中也显示出神经恢复活性。
T4013 SGC2085 HCl

Histone Methyltransferase Chromatin/Epigenetic
SGC2085 HCl 是一种有效的选择性辅激活剂相关的精氨酸甲基转移酶 1 (CARM1) 抑制剂,IC50 为 50 nM,选择性比其他 PRMT 高出数倍。 CARM1 是结直肠癌中 Wnt/β-catenin 转录和肿瘤转化的重要正调节因子,也是雌激素刺激的乳腺癌生长的关键因素,其耗竭导致体内髓性白血病细胞增殖减少。
T35689 MTP 131 acetate

Others Others
MTP 131 acetate 是一种小的线粒体靶向四肽。
T36949 Niaprazine

5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Niaprazine 是有效的组胺 H1 受体拮抗剂,具有抗组胺和抗血清素活性。Niaprazine 在睡眠障碍方面有研究的价值。
T23983 Deutetrabenazine metabolite M4

SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4

Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VMAT2, resulting in decreased uptake
T21315 Folitixorin

ANX-510

ANX-510 is a folate-based biomodulator. It stabilizes the covalent binding of the fluorouracil metabolite FdUMP to thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituen
T26993 CGP 56999A

CGP56999A,CGP-56999A

CGP 56999A is an antagonist of GABA(B) receptor, it enhances expression of brain-derived neurotrophic factor and attenuates dopamine depletion in the rat corpus striatum.
T30807 CG0009

CG-0009,CG 0009

CG0009 is a potent and highly selective glycogen synthase kinase 3 (GSK3) inhibitor that inhibitions proliferation, induces apoptosis, and activates the p53-Bax pathway in breast cancer cells through cyclin D1 depletion. CG0009 inhibit breast cancer cell
T71413 U 26384

U 26384 is a phospholipase A2 inhibitor reduces the severity of cell injury, but does not maintain cell viability in cultured human astroglial cell line UC-11MG during ATP depletion.
T28488 Quinuronium Sulfate

Pirevan,Zothelone,Acaprin

Quinuronium sulfate is a drug used to treat Babesia divergens infections in calves. It did not prevent treated animals from being disease carriers. It may also cause hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH).
T61097 Anticancer agent 70

Anticancer agent 70 (Compound 21) is a potent anticancer compound that demonstrates remarkable cytotoxicity against multiple human cancer cell lines. It induces G0/G1-cell cycle arrest and concurrently elevates the levels of p53 and p21 proteins. Furthermore, Anticancer agent 70 induces ATP depletion and disruption of the mitochondrial membrane potential [1].
T15412 GPP78

CAY10618

Autophagy Autophagy
GPP78 is a potent inhibitor of Nampt (IC50: 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion). GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells (IC50: 3.8 nM by inducing autophagy). GPP78 has anti-cancer and anti-inflammatory effect
T36194 CAY10726

CAY10726

CAY10726 is an arylurea fatty acid. It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent ...
T39243 Janelia Fluor® 585, SE

JF585, SE,JF585,NHS

Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments.
T64293 SLN124

SLN124 是一种 GalNac-siRNA,靶向跨膜丝氨酸蛋白酶 6 (Tmprss6),由与 TMPRSS6-siRNA 结合的三聚体 GalNAc 配体组成。SLN124 具有潜力用做 siRNA 剂,恢复铁调素表达并使 β-地贫中铁稳态正常化。
T25374 Emofolin sodium

NSC139490,MeTHHF disodium,NSC-139490,NSC 139490

Emofolin sodium is the sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity,which competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, deple
T60667 NAT

NAT 是 NAMPT 激活剂的苗头化合物。NAMPT 是研究与 NAD 耗竭相关的许多疾病 ,例如如神经退行性疾病的有吸引力的靶点,由于其为 NAD 回收途径中的限速酶。
T35652 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.
T76824 Quilizumab

Quilizumab (Anti-Human NGcGM3 Recombinant Antibody) 是一种人源化 IgG1κ 单克隆抗体。Quilizumab 靶向膜表达的IgE 的 M1-prime 片段,导致IgE 转换和记忆 B 细胞耗尽。Quilizumab 具有哮喘研究的潜力。
T36570 KUS121

KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, an inducer of ER stress, in HeLa cells when used at concentrations of 20, 50, and 50 μM, respectively. KUS121 (100 μM) inhibits ATP depletion and cell death induced by oxygen-glucose deprivation (OGD) in rat primary cortical neurons in anin vitromodel of cerebral ischemia.2It red...
T37578 GPP 78 hydrochloride

GPP 78 hydrochloride 是一种有效的烟酰胺磷酸核糖转移酶 (Nampt) 抑制剂,对 NAD 消耗的 IC50 为 3 nM。GPP 78 hydrochloride 通过诱导自噬对神经母细胞瘤细胞 SH-SY5Y 具有毒性,IC50 为 3.8 nM。GPP78 具有抗癌和抗炎作用。
T73697 Denileukin diftitox

Denileukin diftitox (DAB 389IL-2) 是一种融合蛋白毒素,将白喉毒素 (DT) 与白细胞介素 2 (IL-2) 结合,专门针对表达高亲和力IL-2受体 (IL-2R)、CD25 的细胞。它通过与IL-2R阳性细胞结合并利用白喉毒素片段的内化作用来抑制蛋白质合成,从而达到耗尽目标细胞的效果。
T37922 7(Z),11(Z)-Pentacosadiene

Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C monoenes and females produce 27- and 29-C dienes. Each of these lipids plays specific roles in regulating male sexual behavior, with dienes stimulating courtship. 7(Z),11(Z)-Pentacosadiene is a 25-C hydrocarbon that is found in low abundance on cuticles of mature Drosophila fema...
T14553 BHPI

Others Others
BHPI is a potent inhibitor of nuclear estrogen–ERα-regulated gene expression. Elicits sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor, the unfolded protein response (UPR), and persistent inhibition of protein synthesis.
T82609 Dargistotug

M-6223

Dargistotug (M-6223) 是一种靶向 TIGIT 的全人 IgG1 类型单克隆抗体。TIGIT 是一种带有 Ig 结构域和 ITIM 的 T 细胞免疫受体,充当抑制性免疫检查点。Dargistotug 通过与 CD155 等分子结合抑制 NK 细胞活性,减少细胞因子分泌,并能直接或间接地抑制效应 T 细胞活性和上调 Tregs,从而发挥免疫抑制作用。
T13907 Sulfo-ara-F-NMN

CZ-48

Others Others
Sulfo-ara-F-NMN 是一种具有细胞渗透性的烟酰胺单核苷酸 (NMN) 的类似物。Sulfo-ara-F-NMN 对激活 SARM1具有选择性,对 CD38具有抑制作用, IC50 约为 10 μM。Sulfo-ara-F-NMN 对具有更高的环化酶活性 CZ-48或 NMN 的激活会引起 SARM1的构象变化,导致 cADPR 的产生、NAD 的消耗和非凋亡细胞死亡。
T74174 JB170

JB170 是一种强效且高度特异性的PROTAC 介导的AURORA-A 降解剂 (DC50=28 nM),通过将 Alisertib 连接至Cereblon 配体 Thalidomide 而形成。JB170 优先结合 AURORA-A (EC50=193 nM) 而不是 AURORA-B (EC50=1.4µM)。JB170 介导的 S 期阻滞是由 AURORA-A 耗竭引起的。JB170 对 AURORA-A 激酶的非催化功能具有很好的抑制能力。
T37295 Ganglioside GM1 Asialo Mixture

Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody. The percentage of ganglioside GM1 asialo-positive na...
T36507 Tetrachlorohydroquinone

Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes. In vivo, TCHQ induces glutathione (GSH) depletion in mouse liver.
T36521 Alaproclate (hydrochloride)

Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s = 18, 4, 8, and 12 mg/kg, respectively).1 Alaproclate inhibits NMDA-evoked currents and depolarization-induced voltage-dependent potassium currents in rat hippocampal neurons (IC50s = 1.1 and 6.9 μM, respectively) and does not inhibit GABA-evoked currents when used at concentratio...
T37248 Pantothenate Kinase Inhibitor

Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK; IC50s = 70, 92, and 25 nM for PanK1β, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A .1It binds to the ATP-PanK3 complex with an apparent binding constant of 300 nM and exhibits mixed-type inhibition with respect to ATP and pantothenate. PANKi inhibits CoA biosynthesis in C3A cells (IC50= 0.9 μM) with no effect on cell viability when used at concentrations up to...

化合物

6-Aminonicotinamide
Cat.No: T7545
Synonym:
Target: Others
Alemtuzumab
Cat.No: T9919
Synonym:
Target: Others
CAY10678
Cat.No: T38369
Synonym:
Target: Prostaglandin Receptor, PD-1/PD-L1
PFM39
Cat.No: T38709
Synonym:
Target: Others
PTC-028
Cat.No: T16680
Synonym:
Target: Apoptosis, BMI-1
amyloid P-IN-1
Cat.No: T14283
Synonym:
Target: Beta Amyloid
Palmitoylcarnitine chloride
Cat.No: T13810
Synonym: Palmitoyl DL-carnitine chloride
Target: PKC
Imidazole ketone erastin
Cat.No: T5523
Synonym: IKE
Target: Ferroptosis
Miridesap
Cat.No: T7295
Synonym: Ro63-8695,CPHPC,GSK2315698
Target: Others
Benralizumab
Cat.No: T10497
Synonym: BIW-8405,MEDI-563
Target: Apoptosis, IL Receptor, Interleukin
Indoximod
Cat.No: T6543
Synonym: NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan,吲哚莫德
Target: Indoleamine 2,3-Dioxygenase (IDO)
Losulazine
Cat.No: T68095
Synonym:
Target: Dopamine Receptor, Norepinephrine
Teneliximab
Cat.No: T76830
Synonym: Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819
Target: TNF
Tinidazole
Cat.No: T0893
Synonym: 替硝唑,CP12574
Target: Antibacterial, Antibiotic
MAO-IN-M30 dihydrochloride
Cat.No: T38034
Synonym: M 30 dihydrochloride
Target: Monoamine Oxidase
SGC2085 HCl
Cat.No: T4013
Synonym:
Target: Histone Methyltransferase
MTP 131 acetate
Cat.No: T35689
Synonym:
Target: Others
Niaprazine
Cat.No: T36949
Synonym:
Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Deutetrabenazine metabolite M4
Cat.No: T23983
Synonym: SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4
Target:
Folitixorin
Cat.No: T21315
Synonym: ANX-510
Target:
CGP 56999A
Cat.No: T26993
Synonym: CGP56999A,CGP-56999A
Target:
CG0009
Cat.No: T30807
Synonym: CG-0009,CG 0009
Target:
U 26384
Cat.No: T71413
Synonym:
Target:
Quinuronium Sulfate
Cat.No: T28488
Synonym: Pirevan,Zothelone,Acaprin
Target:
Anticancer agent 70
Cat.No: T61097
Synonym:
Target:
GPP78
Cat.No: T15412
Synonym: CAY10618
Target: Autophagy
CAY10726
Cat.No: T36194
Synonym: CAY10726
Target:
Janelia Fluor® 585, SE
Cat.No: T39243
Synonym: JF585, SE,JF585,NHS
Target:
SLN124
Cat.No: T64293
Synonym:
Target:
Emofolin sodium
Cat.No: T25374
Synonym: NSC139490,MeTHHF disodium,NSC-139490,NSC 139490
Target:
NAT
Cat.No: T60667
Synonym:
Target:
2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
Cat.No: T35652
Synonym:
Target:
Quilizumab
Cat.No: T76824
Synonym:
Target:
KUS121
Cat.No: T36570
Synonym:
Target:
GPP 78 hydrochloride
Cat.No: T37578
Synonym:
Target:
Denileukin diftitox
Cat.No: T73697
Synonym:
Target:
7(Z),11(Z)-Pentacosadiene
Cat.No: T37922
Synonym:
Target:
BHPI
Cat.No: T14553
Synonym:
Target: Others
Dargistotug
Cat.No: T82609
Synonym: M-6223
Target:
Sulfo-ara-F-NMN
Cat.No: T13907
Synonym: CZ-48
Target: Others
JB170
Cat.No: T74174
Synonym:
Target:
Ganglioside GM1 Asialo Mixture
Cat.No: T37295
Synonym:
Target:
Tetrachlorohydroquinone
Cat.No: T36507
Synonym:
Target:
Alaproclate (hydrochloride)
Cat.No: T36521
Synonym:
Target:
Pantothenate Kinase Inhibitor
Cat.No: T37248
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T0809 Dicoumarol

Dicumarol,双羟香豆素,双香豆素

Dehydrogenase; NADPH; PDK Metabolism; PI3K/Akt/mTOR signaling
Dicoumarol (Dicumarol) 是一种 NAD(P)H: 醌氧化还原酶 1 和PDK1的抑制剂,它们的IC50值分别为 0.37 和 19.42 μM。
T5S1097 Neferine

(R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱

Apoptosis; NF-κB; Autophagy Apoptosis; Autophagy; NF-κB
Neferine ((-)-Neferine) 是一种双苄基异喹啉类生物碱,可强效抑制NF-κB 激活,具有抗肿瘤活性。
T2S0618 β-Elemonic Acid

3-oxo Tirucallic Acid,β-岚香酮酸,Beta-Elemonic acid,3-Oxotirucallenoic Acid,β-榄香酮酸,Elemadienonic Acid

Apoptosis; Reactive Oxygen Species; COX Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
β-Elemonic Acid (3-Oxotirucallenoic Acid) 是从乳香树中分离得到的一种三萜,具有抗癌和抗炎作用。它抑制脯氨酰内肽酶,诱导细胞凋亡,活性氧和COX-2表达。
T0791 Reserpine

利血平,Serpalan,Serpasil,Serpivite

Others; Potassium Channel; MRP; Monoamine Transporter; Autophagy Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others
Reserpine (Serpalan) 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。
T5300 Ammonium formate

甲酸铵,Formic acid ammonium salt

Others Others
Ammonium formate (Formic acid ammonium salt) 是最简单的羧酸。它通过抑制细胞色素氧化酶活性(电子传递链的末端电子受体)来负责代谢性酸中毒和破坏线粒体电子传递和能量产生。
T21772 Reserpine hydrochloride

Reserpine hydrochloride 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。

天然产物

Dicoumarol
Cat.No: T0809
Synonym: Dicumarol,双羟香豆素,双香豆素
Target: Dehydrogenase, NADPH, PDK
Neferine
Cat.No: T5S1097
Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱
Target: Apoptosis, NF-κB, Autophagy
β-Elemonic Acid
Cat.No: T2S0618
Synonym: 3-oxo Tirucallic Acid,β-岚香酮酸,Beta-Elemonic acid,3-Oxotirucallenoic Acid,β-榄香酮酸,Elemadienonic Acid
Target: Apoptosis, Reactive Oxygen Species, COX
Reserpine
Cat.No: T0791
Synonym: 利血平,Serpalan,Serpasil,Serpivite
Target: Others, Potassium Channel, MRP, Monoamine Transporter, Autophagy
Ammonium formate
Cat.No: T5300
Synonym: 甲酸铵,Formic acid ammonium salt
Target: Others
Reserpine hydrochloride
Cat.No: T21772
Synonym:
Target:
TargetMol Loading
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