首页工具

登录

搜索结果

Search Results for " vas "

Targets Recommended: Vasopressin Receptor Apoptosis NADPH-oxidase

146

抑制剂 & 化合物

12

天然产物

1

化合物库

11

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L5400	抗心血管疾病化合物库		1408 compounds
	1408 种心血管疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

抗心血管疾病化合物库

Cat.No: L5400

Compounds: 1408

Cat. No.	Product Name	Target	Signaling Pathways
T29097	VAS 3947 VA-S3947,VA S3947,VAS3947	Apoptosis; NADPH-oxidase	Apoptosis; Immunology/Inflammation
	VAS 3947 是一种特异的 NADPH 氧化酶 (NOX) 抑制剂。VAS 3947具有强大的抗血小板作用, 通过 UPR 激活，主要由于蛋白质聚集和错误折叠，独立于抗 NOX 活性诱导细胞凋亡。
T4359	VAS2870	NADPH	Metabolism
	VAS2870 是一种NADPH 氧化酶抑制剂。
T69945	MPT0L145
	MPT0L145 is a first-in-class PIK3C3/FGFR inhibitor.
T9857	Vasopressin antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP)	Endogenous Metabolite	Metabolism
	Vasopressin (argipressin) 是一种由下丘脑神经元合成的环状九肽，是肽原激素合成中的一种激素。Vasopressin 参与下丘脑-垂体-肾上腺轴调节过程，增加无溶质水从肾小管的滤液中重新吸收回循环中的量，收缩小动脉提高压强，增强促肾上腺皮质激素释放因子的刺激作用调节垂体促肾上腺皮质激素分泌。Vasopressin 在神经传导过程中可作为神经递质，与特定的 G 蛋白偶联受体结合发挥作用。
T2753	Avasimibe PD-148515,阿伐麦布,CI-1011	P450; Acyltransferase	Metabolism
	Avasimibe (PD-148515) 是一种口服有效的酰基辅酶 A: 胆固醇酰基转移酶 (ACAT) 抑制剂，对 ACAT1和 ACAT2的 IC50分别为 24 和 9.2 µM。Avasimibe 在前列腺癌中有研究的价值。
T1676	Rosuvastatin 罗伐他汀,ZD 4522,瑞舒伐他汀	Potassium Channel; HMG-CoA Reductase; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Rosuvastatin (ZD 4522) 是一种抗血脂药，可竞争性抑制羟甲基戊二酰辅酶 A 还原酶，用于降低血浆胆固醇水平和预防心血管疾病。它降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流，IC50为 195 nM，延迟心脏复极化，延长动作电位持续时间和校正 QT 间期间隔。
T3116	Atorvastatin hemicalcium salt Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,阿托伐他汀钙,Sortis	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Atorvastatin hemicalcium salt (Atorvastatin Calcium) 是一种口服有效的 HMG-CoA 还原酶抑制剂，可用作降低胆固醇的药物。它抑制人 SV-SMC 增殖和侵袭，IC50分别为 0.39 μM 和 2.39 μM。
T4551	Acrivastine Acrivastin,阿伐斯汀,BW825C,Semprex	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Acrivastine (Acrivastin) 是一种短效组胺 1 受体拮抗剂，可用于研究过敏性鼻炎。
T25276	Crilvastatin PMD387,PMD 387,PMD-387	HMG-CoA Reductase	Metabolism
	Crilvastatin (PMD 387) 是一种新型非竞争性羟甲基戊二酰辅酶 A 还原酶抑制剂，具有降胆固醇活性，可抑制遗传性高胆固醇血症大鼠的胆固醇吸收。
T21405	Fluvastatin Canef,XU-62320,Vastin,Cranoc,Lescol	HMG-CoA Reductase	Metabolism
	Fluvastatin (XU-62320) 是一种具有高效性和竞争性的 HMG-CoA 还原酶抑制剂（IC50 ：8 nM），可通过依赖 Nrf2 通路抑制血管平滑肌细胞免受氧化应激，用于降低血浆胆固醇水平和预防心血管疾病。
T0229	Rivastigmine SDZ-ENA 713,卡巴拉汀,S-Rivastigmine,Exelon,利凡斯的明	AChE	Neuroscience
	Rivastigmine (Exelon) 是具有口服活性的、有效的、可透过血脑屏障的胆碱酯酶抑制剂，可抑制丁酰胆碱酯酶和乙酰胆碱酯酶，IC50分别为 0.037 μM 和 4.15 μM。它是一种拟副交感神经剂或胆碱能剂，用于研究轻度至中度阿尔茨海默氏型痴呆和帕金森氏病引起的痴呆。
T1487	Fluvastatin sodium XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Fluvastatin sodium (Fluvastatin sodium salt) salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂，IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激，是一种常用的降胆固醇剂。
TQ0045	2-Hydroxy atorvastatin calcium salt	Drug Metabolite	Metabolism
	2-Hydroxy atorvastatin calcium salt 是 Atorvastatin 钙盐的羟基代谢物，Atorvastatin 是一种有效的 HMG-CoA 还原酶抑制剂 (IC50 = 8 nM)。
T9857L	Vasopressin acetate Vasopressin acetate (11000-17-2 Free base)	Endogenous Metabolite	Metabolism
	Vasopressin acetate 是一种环状九肽，在下丘脑中枢合成。 Vasopressin acetate 作为一种神经递质，通过与特定的 G 蛋白偶联受体结合发挥其作用。
T12652	(Rac)-5-Keto Fluvastatin 5-Ketofluvastatin,3-Hydroxy-5-Keto Fluvastatin,rac 5-Keto Fluvastatin	Others	Others
	(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) 是 Fluvastatin 的杂质，Fluvastatin 是一种 HMG-CoA 还原酶的抑制剂。
T12490	Pitavastatin lactone	Others	Others
	Pitavastatin lactone 是 Pitavastatin 在人体中的主要代谢产物。Pitavastatin 是 HMG-CoA 还原酶竞争性抑制剂。
T5600	Darovasertib LXS196	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Darovasertib (LXS196) 是一种有效的、选择性的和具有口服活性的蛋白激酶C(PKC) 抑制剂，有用于葡萄膜黑素瘤的研究潜力，对 PKCα、PKCθ 和 GSK3β 的 IC50值分别为 1.9、0.4 和 3.1 μM。
T20887	Atorvastatin Sodium Lipitor	LDL; Aquaporin; HMG-CoA Reductase	Membrane transporter/Ion channel; Metabolism
	Atorvastatin Sodium (Lipitor) 是一种HMG-CoA 还原酶的竞争性抑制剂，增加肝细胞上低密度脂蛋白（LDL）受体的表达。Atorvastatin sodium 处理抑制水汽蛋白4来减轻缺血性脑水肿。
T10324	Anhydrosimvastatin Dehydro simvastatin,脱水辛伐他汀	HMG-CoA Reductase	Metabolism
	Anhydrosimvastatin (Dehydro simvastatin) 是 Simvastatin 的一种杂质。其中Simvastatin 是竞争性的 HMG-CoA 还原酶抑制剂。
T13131	Tert-Buthyl Pitavastatin	HMG-CoA Reductase	Metabolism
	tert-Buthyl Pitavastatin 是 Pitavastatin 的代谢产物。其中Pitavastatin 是HMG-CoA 还原酶抑制剂。
T14342	Atorvastatin lactone	HMG-CoA Reductase	Metabolism
	Atorvastatin lactone 是一种 Atorvastatin 的前药。其中 Atorvastatin 是口服具有活力的 3- 羟基 -3- 甲基戊二酰辅酶 A 还原酶抑制剂。
T1510	Rosuvastatin calcium ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙	Potassium Channel; HMG-CoA Reductase; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Rosuvastatin calcium (ZD4522) 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂，具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用，还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流，延迟心脏复极化，来延长动作电位持续时间和校正 QT 间期间隔。
T2534	Pitavastatin calcium P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,匹伐他汀钙,NK-104	Apoptosis; Mitophagy; Endogenous Metabolite; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Pitavastatin calcium (NK-104) 是一种羟甲基戊二酰-CoA 还原酶抑制剂。它在 HepG2 细胞中抑制乙酸合成胆固醇的IC50为 5.8 nM。它是高效的肝细胞低密度脂蛋白胆固醇受体诱导剂。具有抗癌活性。
T1920	Capivasertib AZD5363	Akt; PKA; mTOR; Autophagy	Autophagy; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	Capivasertib (AZD5363) 是一种广谱的 AKT 抑制剂，对 Akt1、Akt2 和 Akt3 均有抑制活性 (IC50=3/7/7 nM)，具有口服活性。Capivasertib 具有抗肿瘤活性，可以用于治疗乳腺癌。
T24865	Tenivastatin L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid	ROS; HMG-CoA Reductase	Immunology/Inflammation; Metabolism
	Tenivastatin (Simvastatin acid) 是一种抗高脂血症的 HMG-CoA 还原酶抑制剂，抑制活性氧 (ROS) 产生，可用于研究原发性高脂血症。
T25285	Dalvastatin RG-12561,RG 12561,RG12561	HMG-CoA Reductase	Metabolism
	Dalvastatin (RG-12561) 是一种可口服的 HMG-CoA 还原酶和降胆固醇合成的抑制剂。Dalvastatin 竞争性地抑制大鼠肝脏HMG-CoA还原酶，IC50值为3.4 nmol / l。 Dalvastatin 在在大鼠实验中，抑制肝切片中的胆固醇生物合成，ED50值为0.9。
TP1400L	[Arg8]-Vasotocin acetate（113-80-4 free base)	Others	Others
	[Arg8]-Vasotocin acetate（113-80-4 free base) 是一种存在于非哺乳动物脊椎动物神经垂体中的激素，与加压素和催产素有关。
T71628	Fluvastatin potassium
	Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.
T12757	Rosuvastatin D3 Sodium	Others	Others
	Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T38740	Rivastigmine carbamate impurity 利凡斯的明氨基甲酸酯杂质；利瓦斯的明氨基甲酸酯杂质；卡巴拉汀氨基甲酸酯杂质；利斯的明氨基甲酸酯杂质,3-Nitrophenyl ethyl(methyl)carbamate
	Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is a byproduct found in Rivastigmine, which is recognized as a powerful and orally active inhibitor of cholinesterase (ChE). Specifically, Rivastigmine effectively inhibits both butyrylcholinesterase (BChE) and acetylcholinesterase (AChE), with IC50 values of 0.037 μM and 4.15 μM, respectively.
T14931	Cerivastatin	Others	Others
	Cerivastatin is a highly potent, well-tolerated, and orally active HMG-CoA reductase inhibitor (Ki: 1.3 nM/L). Cerivastatin also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition with anti-cancer effect. Cerivastatin r
T22405	Pravastatin	Others	Others
	Pravastatin is a lipoprotein-lowering drug via reversibly inhibiting hydroxymethylglutaryl-CoA (HMG-CoA) reductase and the synthesis of very-low-density lipoproteins.
T10136	4-Acetylsimvastatin	Others	Others
	4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).
T82900	Bemfivastatin hemicalcium PPD 10558 hemicalcium
	Bemfivastatin (PPD 10558) hemicalcium 作为口服HMG-CoA还原酶抑制剂，具备有效的降脂作用并能增强肝脏提取活性。该化合物的未观察到不良反应水平(NOAEL)在大鼠发育毒性研究中超过320 mg/kg/d，在家兔母体毒性及发育毒性研究中分别超过12.5 mg/kg/d和25 mg/kg/d。Bemfivastatin hemicalcium 适用于对他汀类药物不耐受且患有他汀相关性高胆固醇血症性肌痛的研究。
T76573	[8-L-arginine] deaminovasopressin
	[8-L-arginine] deaminovasopressin (dAVP) 是一种抗利尿激素类似物。
T20765	Atorvastatin 阿托伐他汀,阿伐他汀	HMG-CoA Reductase; Autophagy	Autophagy; Metabolism
	Atorvastatin 是一种具有口服活性的 HMG-CoA 还原酶抑制剂，通过激活肝细胞色素p450加快代谢，具有有效降低血脂的能力。Atorvastatin 以 IC50 值分别为 0.39 μM 和 2.39 μM 来抑制人 SV-SMC 细胞的增殖和侵袭。Atorvastatin 与氯吡格雷同时服用两种可能会导致患者血栓事件增加。
TP2136	(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin
	Selective vasopressin V1A receptor antagonist. Inhibits vasopressin and oxytocin-induced increases in intracellular calcium concentrations in vitro (IC50 values are 5 and 30 nM respectively). Exhibits potent and prolonged antivasopressor activity and indu
TP1352	[Arg8]-Vasotocin TFA (113-80-4 free base) [Arg8]-Vasotocin TFA
	[Arg8]-Vasotocin (TFA) is a nonmammalian vertebrate neurohypophyseal peptide.
T80197	Vasopressin Dimer (parallel) (TFA)	Vasopressin Receptor	GPCR/G Protein
	Vasopressin Dimer (parallel) TFA为Vasopressin的平行二聚体，能够激活G蛋白偶联受体V1aR、V1bR、V2R及OTR四种。
T83502	[Deamino-4-valine, 8-D-arginine]-Vasopressin dVDAVP
	[Deamino-4-valine, 8-D-arginine]-Vasopressin (dVDAVP)为一种抗利尿药，具有高效性、特异性以及延长的药效特点。
T35718	N-desmethyl Rosuvastatin (sodium salt hydrate)
	N-desmethyl Rosuvastatin is an active metabolite of the HMG-CoA reductase inhibitor rosuvastatin .1,2N-desmethyl Rosuvastatin is formed when rosuvastatin undergoes demethylation, primarily by the cytochrome P450 (CYP) isoform CYP2C9 and to a lesser extent by CYP2C19 and CYP3A4.1 1.Macwan, J.S., Ionita, I.A., and Akhlaghi, F.A simple assay for the simultaneous determination of rosuvastatin acid, rosuvastatin-5S-lactone, and N-desmethyl rosuvastatin in human plasma using liquid chromatography-tand...
T37642	Pravastatin lactone
	Pravastatin lactone is a metabolite of pravastatin , a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that is a ring-hydroxylated metabolite of mevastatin . Pravastatin lactone is formed when pravastatin undergoes acid-catalyzed non-enzymatic lactonization in the stomach following oral administration.
T10070	2'-Ethyl Simvastatin	HMG-CoA Reductase	Metabolism
	2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.
T10241	Acrivastine D7 BW825C D7	Others	Others
	Acrivastine D7 is a deuterium labeled Acrivastine. Acrivastine is a short acting antagonist of histamine 1 receptor.
T69006	Atorvastatin lysine
	Atorvastatin lysine is a selective and competitive HMGCR (HMG-CoA reductase) inhibitor.
T70300	Avasimibe sodium
	Avasimibe sodium is an acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.
T10399	Atorvastatin 3-Deoxyhept-2E-Enoic Acid (2E)-2,3-Dehydroxy Atorvastatin	Others	Others
	Atorvastatin 3-Deoxyhept-2E-Enoic Acid is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T21363	Atorvastatin calcium trihydrate CI-981,atorvastatin, calcium salt,CI981,Atorvastatin,CI 981
	Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease.
T64174	Vasopressin V2 receptor antagonist 1
	Vasopressin V2 receptor antagonist 1 (Compound 4g) 是一种 vasopressin V2receptor (V2R) 拮抗剂 (Ki: 3.8 nM)。Vasopressin V2 receptor antagonist 1 可以用于研究常染色体显性多囊肾病 (ADPKD)。
T10130	(3S,5R)-Pitavastatin calcium	Others	Others
	(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.

化合物

Cat.No: T29097

Synonym: VA-S3947,VA S3947,VAS3947

Target: Apoptosis, NADPH-oxidase

Cat.No: T4359

Target: NADPH

Cat.No: T69945

Cat.No: T9857

Synonym: antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP)

Target: Endogenous Metabolite

Cat.No: T2753

Synonym: PD-148515,阿伐麦布,CI-1011

Target: P450, Acyltransferase

Cat.No: T1676

Synonym: 罗伐他汀,ZD 4522,瑞舒伐他汀

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Atorvastatin hemicalcium salt

Cat.No: T3116

Synonym: Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,阿托伐他汀钙,Sortis

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T4551

Synonym: Acrivastin,阿伐斯汀,BW825C,Semprex

Target: Histamine Receptor

Cat.No: T25276

Synonym: PMD387,PMD 387,PMD-387

Target: HMG-CoA Reductase

Cat.No: T21405

Synonym: Canef,XU-62320,Vastin,Cranoc,Lescol

Target: HMG-CoA Reductase

Cat.No: T0229

Synonym: SDZ-ENA 713,卡巴拉汀,S-Rivastigmine,Exelon,利凡斯的明

Target: AChE

Fluvastatin sodium

Cat.No: T1487

Synonym: XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

2-Hydroxy atorvastatin calcium salt

Cat.No: TQ0045

Target: Drug Metabolite

Vasopressin acetate

Cat.No: T9857L

Synonym: Vasopressin acetate (11000-17-2 Free base)

Target: Endogenous Metabolite

(Rac)-5-Keto Fluvastatin

Cat.No: T12652

Synonym: 5-Ketofluvastatin,3-Hydroxy-5-Keto Fluvastatin,rac 5-Keto Fluvastatin

Target: Others

Pitavastatin lactone

Cat.No: T12490

Target: Others

Cat.No: T5600

Synonym: LXS196

Target: PKC

Atorvastatin Sodium

Cat.No: T20887

Synonym: Lipitor

Target: LDL, Aquaporin, HMG-CoA Reductase

Anhydrosimvastatin

Cat.No: T10324

Synonym: Dehydro simvastatin,脱水辛伐他汀

Target: HMG-CoA Reductase

Tert-Buthyl Pitavastatin

Cat.No: T13131

Target: HMG-CoA Reductase

Atorvastatin lactone

Cat.No: T14342

Target: HMG-CoA Reductase

Rosuvastatin calcium

Cat.No: T1510

Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Pitavastatin calcium

Cat.No: T2534

Synonym: P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,匹伐他汀钙,NK-104

Target: Apoptosis, Mitophagy, Endogenous Metabolite, HMG-CoA Reductase, Autophagy

Cat.No: T1920

Synonym: AZD5363

Target: Akt, PKA, mTOR, Autophagy

Cat.No: T24865

Synonym: L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid

Target: ROS, HMG-CoA Reductase

Cat.No: T25285

Synonym: RG-12561,RG 12561,RG12561

Target: HMG-CoA Reductase

[Arg8]-Vasotocin acetate（113-80-4 free base)

Cat.No: TP1400L

Target: Others

Fluvastatin potassium

Cat.No: T71628

Rosuvastatin D3 Sodium

Cat.No: T12757

Target: Others

Rivastigmine carbamate impurity

Cat.No: T38740

Synonym: 利凡斯的明氨基甲酸酯杂质；利瓦斯的明氨基甲酸酯杂质；卡巴拉汀氨基甲酸酯杂质；利斯的明氨基甲酸酯杂质,3-Nitrophenyl ethyl(methyl)carbamate

Cat.No: T14931

Target: Others

Cat.No: T22405

Target: Others

4-Acetylsimvastatin

Cat.No: T10136

Target: Others

Bemfivastatin hemicalcium

Cat.No: T82900

Synonym: PPD 10558 hemicalcium

[8-L-arginine] deaminovasopressin

Cat.No: T76573

Cat.No: T20765

Synonym: 阿托伐他汀,阿伐他汀

Target: HMG-CoA Reductase, Autophagy

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin

Cat.No: TP2136

[Arg8]-Vasotocin TFA (113-80-4 free base)

Cat.No: TP1352

Synonym: [Arg8]-Vasotocin TFA

Vasopressin Dimer (parallel) (TFA)

Cat.No: T80197

Target: Vasopressin Receptor

[Deamino-4-valine, 8-D-arginine]-Vasopressin

Cat.No: T83502

Synonym: dVDAVP

N-desmethyl Rosuvastatin (sodium salt hydrate)

Cat.No: T35718

Pravastatin lactone

Cat.No: T37642

2'-Ethyl Simvastatin

Cat.No: T10070

Target: HMG-CoA Reductase

Cat.No: T10241

Synonym: BW825C D7

Target: Others

Atorvastatin lysine

Cat.No: T69006

Avasimibe sodium

Cat.No: T70300

Atorvastatin 3-Deoxyhept-2E-Enoic Acid

Cat.No: T10399

Synonym: (2E)-2,3-Dehydroxy Atorvastatin

Target: Others

Atorvastatin calcium trihydrate

Cat.No: T21363

Synonym: CI-981,atorvastatin, calcium salt,CI981,Atorvastatin,CI 981

Vasopressin V2 receptor antagonist 1

Cat.No: T64174

(3S,5R)-Pitavastatin calcium

Cat.No: T10130

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0672	Pravastatin sodium CS-514 Sodium,普伐他汀钠,CS-514 (sodium)	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Pravastatin sodium (CS-514 (sodium)) 是一种 HMG-CoA 还原酶抑制剂，抑制甾醇合成，IC50 为 5.6 μM。
T1207	Lovastatin MK-803,洛伐他汀,Mevinolin	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Lovastatin (MK-803) 是一种 HMG-CoA 还原酶抑制剂，用于降低胆固醇。
T4960	VASICINE	Anti-infection; AChR	Microbiology/Virology; Neuroscience
	Vasicine 是一种分离自Justicia adhatoda 中的喹唑啉类生物碱。它具有抗结核作用。
T8298	Vasicine hydrochloride 鸭嘴花碱盐酸盐,Peganine hydrochloride	Antibacterial; Antibiotic	Microbiology/Virology
	Vasicine hydrochloride (Peganine hydrochloride) 是从Justicia adhatoda 中分离得到的一种喹唑啉类生物碱，有抗结核活性。
TC0039	Vasicinone	Others	Others
	Vasicinone 是一种喹唑啉类生物碱，分离自凡士林植物中。它是具有研究帕金森病和其他氧化应激相关神经退行性疾病的潜力。
T0683	Mevastatin Compactin,ML236B,美伐他汀	Apoptosis; Antibacterial; Antibiotic; HMG-CoA Reductase; Autophagy; Lipid	Apoptosis; Autophagy; Metabolism; Microbiology/Virology
	Mevastatin (ML236B) 是他汀类 HMG-CoA 还原酶抑制剂。它是一种降脂药，可诱导细胞凋亡，将癌细胞阻滞在 G0/G1期。它还可增加内皮型一氧化氮合酶的 mRNA 和蛋白质水平。它有抗肿瘤活性，用于心血管疾病的研究。
T0687	Simvastatin 辛伐他汀,MK-0733,MK 733	Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM)，具有口服活性。Simvastatin 具有降血脂活性，可以抑制肝脏产生胆固醇，还可以用于预防心血管疾病。
TN1570	Deoxyvasicinone 脱氧鸭嘴花酮碱	Others	Others
	Deoxyvasicinone derivatives can be considered as promising lead molecules for the development of more potent inhibitors of NEDD8-activating enzyme.
TN5222	Vasicinol	Others	Others
	Vasicinol shows a high sucrase inhibitory activity, and the IC50 values was 250 μM.vasicinol could be an useful treatment for metabolic disorders.Vasicinol and vasicinone severe antifertility effects are exhibited by vasicinol against Dysdercus skoenigii
TN5223	Vasicinolone	Antifection	Microbiology/Virology
	Vasicinolone has anti-inflammatory, and antimicrobial activities.
T12681	(±)-Vasicine (±)-Peganine	Others	Others
	(±)-Vasicine is the racemate of Vasicine. Vasicine isolated from Peganum harmala seeds, with anti-ulcer activity.
T16885	Simvastatin acid ammonium 辛伐他汀铵盐,Tenivastatin ammonium	Others	Others
	Simvastatin ammonium is an active metabolite of simvastatin lactone mediated. Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 ge

天然产物

Pravastatin sodium

Cat.No: T0672

Synonym: CS-514 Sodium,普伐他汀钠,CS-514 (sodium)

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T1207

Synonym: MK-803,洛伐他汀,Mevinolin

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T4960

Target: Anti-infection, AChR

Vasicine hydrochloride

Cat.No: T8298

Synonym: 鸭嘴花碱盐酸盐,Peganine hydrochloride

Target: Antibacterial, Antibiotic

Cat.No: TC0039

Target: Others

Cat.No: T0683

Synonym: Compactin,ML236B,美伐他汀

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Cat.No: T0687

Synonym: 辛伐他汀,MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Deoxyvasicinone

Cat.No: TN1570

Synonym: 脱氧鸭嘴花酮碱

Target: Others

Cat.No: TN5222

Target: Others

Cat.No: TN5223

Target: Antifection

(±)-Vasicine

Cat.No: T12681

Synonym: (±)-Peganine

Target: Others

Simvastatin acid ammonium

Cat.No: T16885

Synonym: 辛伐他汀铵盐,Tenivastatin ammonium

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00823	VEGF165 Protein, Human, Recombinant (His & Avi) 血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC70609,VPF,...	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189.
TMPK-00826	VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated VAS,VEGFMGC70609,RP1-261G23.1,血管内皮生长因子,VEGFA,VPF,MV...	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189.
TMPK-00825	VEGF121 Protein, Human, Recombinant (His & Avi) VPF,VEGF,VEGFA,VEGFMGC70609,血管内皮生长因子,MGC70609,RP1-261G23.1,M...	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189.
TMPK-00822	VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled RP1-261G23.1,VEGFA,MGC70609,VEGF,VEGFMGC70609,VPF,VAS	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPH-02303	Vasculin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Functions as a GC-rich promoter-specific transactivating transcription factor.
TMPH-02263	VASH1 Protein, Human, Recombinant (His)	Human	E. coli
	Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells a...
TMPY-03058	SLITL2/VASN Protein, Human, Recombinant (His) SLITL2,vasorin	Human	HEK293
	Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after ...
TMPH-03716	Invasin Protein, Yersinia enterocolitica, Recombinant (His & SUMO)	Yersinia enterocolitica	E. coli
	Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins.
TMPJ-00572	Vasorin Protein, Human, Recombinant (His) Vasorin,VASN,SLITL2,Protein Slit-Like 2	Human	Human Cells
	Vasorin is a Type I membrane protein, which is predominantly expressed in vascular smooth muscle cells in a developmentally regulated pattern. The expression level of Vasorin can be down regulated during vessel repair after arterial injury. Vasorin binds to transforming growth factor beta (TGF-β) and attenuates TGF-β signaling in vitro.
TMPH-02304	Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation.
TMPH-00028	Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP) Protein Rep78	AAV-2	E. coli
	Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a priming site for initiation of the synthesis of a complementary strand. Plays also a role as transcriptional regulator, DNA helicase and as key factors in site-specific integration of the viral genome. Regulates host PKA activity by interacting with host PRKX as a mechanism of i...

重组蛋白

VEGF165 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00823

Species: Human

Expression System: HEK293

VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00826

Species: Human

Expression System: HEK293

VEGF121 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00825

Species: Human

Expression System: HEK293

VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled

Cat.No: TMPK-00822

Species: Human

Expression System: HEK293

Vasculin Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02303

Species: Human

Expression System: E. coli

VASH1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02263

Species: Human

Expression System: E. coli

SLITL2/VASN Protein, Human, Recombinant (His)

Cat.No: TMPY-03058

Species: Human

Expression System: HEK293

Invasin Protein, Yersinia enterocolitica, Recombinant (His & SUMO)

Cat.No: TMPH-03716

Species: Yersinia enterocolitica

Expression System: E. coli

Vasorin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00572

Species: Human

Expression System: Human Cells

Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02304

Species: Human

Expression System: E. coli

Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP)

Cat.No: TMPH-00028

Species: AAV-2

Expression System: E. coli

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼