Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Simvastatin ammonium is an active metabolite of simvastatin lactone mediated. Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 252 | 5日内发货 | ||
5 mg | ¥ 413 | 5日内发货 | ||
10 mg | ¥ 663 | 5日内发货 | ||
25 mg | ¥ 1,280 | 5日内发货 | ||
1 mL * 10 mM (in DMSO) | ¥ 455 | 5日内发货 |
Simvastatin acid ammonium 的其他形式现货产品:
产品描述 | Simvastatin ammonium is an active metabolite of simvastatin lactone mediated. Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene. |
体外活性 | The Michaelis-Menten constant (Km) for simvastatin acid uptake by OATP3A1 was 0.017 μM and the Vmax was 0.995 fmol/min/105 cells. There is a pH-dependent effect on organic anion transporting polypeptide 3A1 uptake, with more efficient simvastatin acid uptake at pH5.5 in HEK293 cells transfected with the OATP3A1 gene [1]. |
别名 | 辛伐他汀铵盐, Tenivastatin ammonium |
分子量 | 453.62 |
分子式 | C25H43NO6 |
CAS No. | 139893-43-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
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体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Simvastatin acid ammonium 139893-43-9 Others 辛伐他汀铵盐 Tenivastatin ammonium Inhibitor inhibitor inhibit