146
16
54
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T79365 |
TIM-3-IN-2
|
Immunology/Inflammation related | Immunology/Inflammation |
TIM-3-IN-2 是 Tim3 抑制剂,可以抑制TIM-3与PtdSer、CEACAM1和Gal-9的结合,抑制TIM-3发挥作用。TIM-3-IN-2能够逆转TIM-3介导的促炎细胞因子的作用。 | |||
T73445 | TIM-063 | ||
TIM-063 是一种选择性和细胞可渗透的CaMKK 抑制剂,ATP 竞争性抑制剂,可以直接靶向 CaMKK 的催化结构域,作用于 CaMKKα 和CaMKKβ 的Ki 值分别是 0.35 μM 和 0.2 μM,IC50值分别是 0.63 μM 和 0.96 μM。 | |||
T63029 | TIM-3-IN-1 | ||
TIM-3-IN-1 是能够进一步研究癌症中 TIM-3 免疫调节生物学的有用工具。 | |||
T72358 |
Antimicrobial agent-14
|
Antibacterial | Microbiology/Virology |
Antimicrobial agent-14是一种苄基噻吩磺酰胺衍生物,常作为抗菌剂使用。Antimicrobial agent-14对 Campylobacter coli ATCC33559 的 MIC 值为 200 μM, 可用于研究细菌性食源性胃肠炎。 | |||
T5032 |
Iguratimod
艾拉莫德,T614 |
Others; COX | Immunology/Inflammation; Neuroscience; Others |
Iguratimod (T614) 是一种抗风湿药,作为 COX-2 的抑制剂,IC50 为 20 μM (7.7 μg/mL)。它还抑制巨噬细胞迁移抑制因子 (MIF),IC50值为 6.81 μM。 | |||
T68163 |
timcodar
|
||
Timcodar 也被称为VX-853,是一种多药耐药性抑制剂。 | |||
T9984 |
Antimalarial agent 13
N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine |
Parasite | Microbiology/Virology |
Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) 是一种有效的抗疟剂。 | |||
T6011 |
Batimastat
巴马司他,BB94 |
MMP | Proteases/Proteasome |
Batimastat (BB94) 是广谱MMP 抑制剂,能够抑制MMP-1 (IC50:3 nM),MMP-2 (IC50:4 nM),MMP-9 (IC50:4 nM),MMP-7 (IC50:6 nM) 和 MMP-3 (IC50:20 nM)。 | |||
T1593 |
Ezetimibe
依泽替米贝,SCH 58235 |
Others; Nrf2; NPC1L1; Autophagy | Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others |
Ezetimibe (SCH 58235) 是一种膳食胆固醇吸收抑制剂。它是一种NPC1L1抑制剂,是有效的Nrf2激活剂。 | |||
T68006 |
Orilotimod potassium
APO805K1 |
||
Orilotimod potassium (APO805K1)可用于研究斑块状银屑病。 | |||
T2664 |
Timapiprant
OC000459 |
GPR; Prostaglandin Receptor | Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation |
Timapiprant (OC000459) 是一种有效的选择性 D 前列腺素受体 2(DP2) 拮抗剂,IC50为 13 nM。它抑制肥大细胞激活 Th2 淋巴细胞和嗜酸性粒细胞,有效地置换来自人重组 DP2、大鼠重组 DP2 和人天然 DP2 的 [3H] PGD2。 | |||
T22381 |
Antimalarial agent 14
4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone |
Others | Others |
Antimalarial agent 14 (NSC-102533) 是一种生物活性化学品。 | |||
T0221 |
Timonacic
1,3-Thiazolidine-4-carboxylic acid,Thiazolidine-4-carboxylic acid,Detoxepa,Thioproline,Hepalidine,噻莫西酸 |
Annexin A | GPCR/G Protein |
Timonacic (Thioproline) 是一种可用于研究急性病和肝脏疾病的佐剂。它能够诱导逆转,也可用于一些癌症病例的研究。 | |||
T67942 |
Antimicrobial agent-21
|
MAPK | MAPK |
Antimicrobial agent-21是一种有效的丝裂原活化蛋白激酶抑制剂 ,具有抗菌、抗炎和抗肿瘤活性,可用来治疗白内障,溃疡性结肠炎,脑膜炎和川崎氏病帕金森氏症。 | |||
T7537 |
Norgestimate
炔诺肟酯,诺孕酯 |
Progesterone Receptor | Others |
Norgestimate 是一种具有口服活性、高度选择性的孕激素活性和较小雄激素作用的孕激素,是一种合成的孕激素类似物。它可用作口服的避孕药。 | |||
T5325 |
Nifurtimox
硝呋替莫,BAY-2502,BAY-A-2502 |
Dehydrogenase; Parasite | Metabolism; Microbiology/Virology |
Nifurtimox (BAY-A-2502) 是一种用于锥虫病的抗虫剂,可影响乳酸脱氢酶活性。它有潜力研究神经母细胞瘤细胞。 | |||
T10336 |
Antimalarial agent 1
|
Parasite | Microbiology/Virology |
Antimalarial agent 1 是一种抗疟药。 | |||
T22380 |
Nor-benzetimide
3-苯基-[3,4-联哌啶]-2,6-二酮 |
Others; AChR | Neuroscience; Others |
Norbenzetimide 是 Benzetimide 的主要代谢产物。Benzetimide 是一种mAChR 拮抗剂,具有抗胆碱能活性。 | |||
T76702 |
Sutimlimab
|
Complement System | Immunology/Inflammation |
Sutimlimab 是一种新型靶向补体蛋白 C1 的单克隆抗体。Sutimlimab 常当作 C1 抑制剂使用,用于治疗冷凝集素病相关溶血。 | |||
T60073 |
Antimycobacterial agent-4
4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide |
Antibacterial | Microbiology/Virology |
Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) 对结核分枝杆菌具有抗菌活性。 | |||
T67858 |
STIMA-1
2-Vinylquinazolin-4-ol,p53 Activator VII |
Others | Others |
STIMA-1 (2-Vinylquinazolin-4-ol) 是一种活性化合物,可以恢复 p63 的活性。STIMA-1 可以刺激角质形成细胞的增殖和分化。 | |||
T7561 |
Benzetimide hydrochloride
盐酸苄替米特,R4929 |
AChR | Neuroscience |
Benzetimide hydrochloride (R4929) 是毒蕈碱乙酰胆碱受体的拮抗剂,用于治疗神经安定药引起的帕金森症。 | |||
T11205 |
ent-Ezetimibe
ent-SCH 58235,ENT-依折麦布 |
Others | Others |
ent-Ezetimibe (ent-SCH 58235) 是 Ezetimibe 的 RRS 型对映体。其中Ezetimibe 是一种胆固醇吸收 (cholesterol-absorption) 抑制剂,是NPC1L1抑制剂,也是有效的Nrf2激活剂。 | |||
T10337 |
Antimicrobial Compound 1
|
Antibacterial | Microbiology/Virology |
Antimicrobial Compound 1 是一种烷基吡啶鎓化合物,尾部为 12C,头部为 4-羧基。 Antimicrobial Compound 1 对枯草芽孢杆菌和大肠杆菌具有抗菌活性。 | |||
T11244 |
Etimizol
Ethymisol,Ethimizole,Ethymisole |
Others | Others |
Etimizol (Ethimizole) 对缺氧造成的失忆症有效果。 | |||
T62447 |
Paltimatrectinib
PBI-200,PPI-5278 |
Trk receptor; Tyrosine Kinases | Tyrosine Kinase/Adaptors |
Paltimatrectinib (PBI-200) 是一种高效的酪氨酸激酶 (tyrosine kinase) 抑制剂,具有抗癌活性,抑制肌球蛋白相关激酶 A (TrkA) 。Paltimatrectinib 可用于研究膀胱癌、乳腺癌和结直肠癌。 | |||
T11449L |
Golotimod
Gamma-D-glutamyl-L-tryptophan,SCV 07 |
Antibiotic | Microbiology/Virology |
Golotimod (SCV 07) 是一种具有抗菌活性的二肽,具有免疫调节活性,能显著提高抗结核治疗的疗效,诱导胸腺和脾脏细胞增殖,调节巨噬细胞功能,抑制 STAT3 信号传导。Golotimod 可用于研究复发性生殖器单纯疱疹病毒 2 (HSV-2)感染和口腔黏膜炎。 | |||
T1532 |
Pidotimod
|
Others; Antibacterial | Microbiology/Virology; Others |
Pidotimod 是一种具有免疫调节特性的合成二肽。它增加巨噬细胞活性和体液免疫功能。它可研究慢性支气管炎、慢性阻塞性肺疾病 、支气管扩张、慢性特发性荨麻疹等。 | |||
T24567 |
Octimibate
Octimibato |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Octimibate (Octimibato) 是一种非前列腺素类血小板聚集抑制剂和环前列腺素激动剂。Octimibate 可用于治疗心血管疾病,可用于研究动脉粥样硬化和血栓形成。 | |||
T79535 |
Antimalarial agent 30
|
Parasite | Microbiology/Virology |
Antimalarial agent 30 具有抗伯氏疟原虫肝期寄生虫活性和抗疟活性,可用于研究疟感染。 | |||
TQ0056 |
Cefuracetime
SKF81367,头孢呋汀 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefuracetime (SKF81367) 是一种头孢菌素抗生素。 | |||
T25146 |
Bestim
|
Others | Others |
Bestim 是一种合成的免疫调节二肽。 | |||
T11941 |
Manitimus
FK778 |
Others | Others |
Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,. | |||
T63655 | Antimalarial agent 9 | ||
Antimalarial agent 9 是有效的抗疟药,是一种喹啉-咪唑衍生物化合物。Antimalarial agent 9 在体外对 CQ 敏感株(IC50-0.14 μM)和 MDR 株(IC50-0.41 μM) 均显示出明显的抗疟效果,具有较小的细胞毒性和高度的选择性。 | |||
T83217 |
Abetimus
LJP 394 free base |
||
Abetimus (LJP 394 free base)为一种由四个双链DNA (dsDNA) 寡核苷酸构成的免疫抑制剂,其作用机制为通过交联B细胞表面的抗dsDNA抗体,从而降低体内抗dsDNA抗体水平,具备作为系统性红斑狼疮研究工具的潜力。 | |||
T28290 |
Pactimibe
CS 505,CS-505,CS505,Pactimibe free base,帕替麦布 |
||
Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity. | |||
T78951 | Antimalarial agent 24 | Parasite | Microbiology/Virology |
Antimalarial agent 24(Compound 7)是一种抗疟化合物,具有显著的体外(in vitro)活性。针对P. falciparum W2菌株,其IC50值为0.81 μM。同时,Antimalarial agent 24展现在HepG2细胞上的CC50值高于200 μM,表明其对宿主细胞具有较高安全性。 | |||
T79534 | Antimalarial agent 29 | Parasite | Microbiology/Virology |
Antimalarial agent 29 (compound 16) 作为一种效力较高的抗疟化合物,其针对伯氏疟原虫肝期寄生虫的EC500值达到5.2 μM。 | |||
T78514 |
Timiperone
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Timiperone对大脑多巴胺D2受体显示出高亲和力,具备抗精神病效果,能有效抑制刻板行为。该化合物在精神分裂症研究中可被广泛应用。 | |||
T79460 |
Antimalarial agent 28
|
Parasite | Microbiology/Virology |
Antimalarial agent 28 (Compound 2i)为具有针对P. berghei三个发育阶段活性的化合物。该化合物的IC50s针对肝期P. berghei为0.561 μM,对早期配子体为0.14 μM,以及对环期P. berghei为4.34 μM,表明其具有抑制该寄生虫的潜力。 | |||
T80858 |
Vixtimotamab
TandAb T564,AMV-564 |
||
Vixtimotamab (AMV-564; TandAb T564)为一种双特异性四价串联抗体 (TandAb),专一性靶向CD33和CD3抗原,主要用于急性髓系白血病 (AML) 的相关研究。 | |||
T37498 |
Antimycin A4
|
||
Antimycin A4 is an active component of the antimycin A antibiotic complex that is more polar than antimycin A1 , antimycin A2 , and antimycin A3 . Antimycin A4 inhibits ATP-citrate lyase with a Ki value of 64.8 μM. The antimycin A complex is a mixture of antimycins A1, A2, A3, and A4 that demonstrates antifungal, insecticidal, nematocidal, and piscicidal properties. It blocks mitochondrial respiration and can deplete cellular levels of ATP via inhibition of complex III of the mitochondrial elect... | |||
T34263 |
Rastim 30 dkv
|
||
Rastim 30 dkv is a plant growth regulator based on bensoline. | |||
T63413 |
Antimalarial agent 15
|
||
Antimalarial agent 15 是 parasite 抑制剂,表现出抗疟作用,对恶性疟原虫 3D7 的生长具有抑制作用,其 IC50值为20 nM。 | |||
T34771 |
Taglutimide
|
||
Taglutimide is a sedative-hypnotic derivative of glutarimide. | |||
T25673 |
Letimide HCl
MA 1443,MA-1443,MA1443,Letimide hydrochloride |
||
Letimide HCl is an analgesic agent. | |||
T23952L |
Dactimicin sulfate
SF-2052 sulfate,Antibiotic SF 2052 sulfate |
||
Dactimicin is a new aminoglycoside. It also has in vitro activity, post-antibiotic effect, and interaction with other antibiotics. | |||
T82435 |
Etimumotide
|
||
Etimumotide作为一种主动免疫的免疫剂和抗肿瘤剂,显示出其在生物医学领域的双重功能。 | |||
T83044 |
Antimalarial agent 33
|
Parasite | Microbiology/Virology |
Antimalarial agent 33 (compound 5g) 显示针对红细胞期和肝期疟原虫的抗活性,特别是对 K1 恶性疟原虫株,其EC50为1.1 μM。Antimalarial agent 33 还展示出提升的微粒体稳定性(T1/2=29分钟),并且对原代肝细胞未表现出明显的细胞毒效应。 | |||
T62300 | Antimalarial agent 11 | ||
Antimalarial agent 11 (compound 1) 一种有效的抗疟 (antimalarial) 剂,是一种螺环色烷。Antimalarial agent 11 具有良好的抗氯喹 Dd2 菌株的效果 (EC50: 350 nM)。Antimalarial agent 11 能够作用于 D6 (EC50: 1.48 μM) 和 ARC08-022 (EC50: 1.81 μM) 。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16338 |
Norgestimate metabolite Norelgestromin
17-Deacetyl norgestimate,17-Deacylnorgestimate,甲基孕酮 |
Drug Metabolite | Metabolism |
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) 是norgestimate 的一种活性代谢物。它是用于避孕贴片的甾体孕激素,与雌激素乙炔雌二醇结合使用。 | |||
T3394 |
Timosaponin BII
知母皂苷BII,Prototimosaponin A III |
Beta Amyloid; Others; BACE | Neuroscience; Others |
Timosaponin BII (Prototimosaponin A III) 是一种甾体皂苷,发现于知母根茎中,具有神经保护、抗炎和抗氧化作用。 | |||
T3501 |
Colistimethate Sodium
Colistin-1,3,5,9-tetramethanesulfonic A acid,多粘菌素E甲磺酸钠 |
Others | Others |
Colistin-1,3,5,9-tetramethanesulfonic A acid 用于治疗选择有限的患者因选定的需氧革兰氏阴性病原体引起的严重感染。 | |||
T4S1050 |
Pristimerin
扁塑藤素,Celastrol methyl ester |
NF-κB; Antibacterial | Microbiology/Virology; NF-κB |
Pristimerin (Celastrol methyl ester) 是一种可逆的单酰基甘油脂肪酶高效抑制剂,IC50值为93 nM。 | |||
TN1383 |
Timosaponin B III
Anemarsaponin BIII,知母皂苷B3,知母皂苷BIII |
Others; Platelet aggregation | Others |
Timosaponin B III (Anemarsaponin BIII) 是一种具有生物活性的甾体皂苷,从知母中分离出来。Timosaponin B III 具有抗炎、抗血小板聚集和抗抑郁作用。 | |||
T2S2295 |
Timosaponin A1
知母皂苷A1 |
Others | Others |
Timosaponin A1 是一种黄酮类甾体皂苷,分离自知母中。 | |||
T3395 |
Timosaponin AIII
Filiferin B,知母皂苷 A-III,AneMarsaponin A3,Timosaponin A3 |
AChE; mTOR | Neuroscience; PI3K/Akt/mTOR signaling |
Timosaponin AIII (Timosaponin A3) 是一种乙酰胆碱酯酶活性抑制剂,其IC50=35.4 μM。 | |||
T15703 | Lactimidomycin | Others | Others |
Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferative effect on tumor cell lines. It i | |||
TN2274 |
Timosaponin C
知母皂苷C,Timorsaponin C |
Others | Others |
Timorsaponin C is a natural product | |||
T83041 |
Antimicrobial agent-27
|
||
Antimicrobial agent-27 (compound 4),一种齐墩烷型三萜酰化衍生物,源自匙羹藤 (Gymnema sylvestre) 的分离提取。 | |||
T79941 |
Antimycin A2c
|
Apoptosis | Apoptosis |
Anticanceragent 141(compound AE)是一种针对HPV感染宫颈癌具有抑制作用的抗霉素生物碱。该化合物能够抑制宫颈癌HeLa细胞的增殖并导致细胞周期在S期停滞。Anticanceragent 141破坏线粒体功能,诱导caspase依赖性细胞凋亡,并激活ROS介导的泛素依赖性蛋白酶体系统,进而引起E6/E7癌蛋白的降解。 | |||
T75547 | Maritimetin | ||
Maritimein,一种可从雪菊提取的橙酮,具有显著的对diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) 自由基清除能力,IC50值仅为4.12 μM。该化合物因此被广泛应用于心血管疾病的研究领域。 | |||
T70355 |
Flutimide
|
||
Flutimide是一种针对流感病毒核酸内切酶的选择性抑制剂,具有3 μM的IC50值,表现出细胞培养中的抗病毒活性,适用于流感等急性传染性呼吸道疾病的研究。 | |||
TN4498 |
Maritimein
|
Others | Others |
Maritimein 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4498,CAS号为 490-54-0。 | |||
T83396 |
23-Nor-6-oxopristimerol
|
||
23-Nor-6-oxopristimerol 为酚类二萜三萜化合物。 | |||
T35577 |
Phosphatidylserines (bovine)
|
||
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01621 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
TIMD-3,hepatitis A virus cellular receptor 2,HAVcr-... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is AAL65157.1. | |||
TMPY-05227 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated
TIMD3,hepatitis A virus cellular receptor 2,CD366,K... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is AAL65157.1. | |||
TMPY-05581 |
TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated
T-cell immunoglobulin and mucin domain containing 4,SMUCKLER... |
Human | HEK293 Cells |
TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.7 kDa and the accession number is AAH08988.1. | |||
TMPK-01272 |
TIM-4/TIMD4 Protein, Cynomolgus, Recombinant (His)
TIMD4,TIMD-4,TIM-4 |
Cynomolgus | HEK293 Cells |
Tim4 is a transmembrane protein as the phosphatidylserine (PS) receptor, known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed highly in macrophages, and macrophage Tim-4 inhibits inflammation under various conditions of immune activation. TIM-4/TIMD4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.55 kDa and the accession number is XP_005558436.2. | |||
TMPJ-01034 |
TIM Protein, Human, Recombinant (His)
TPI1,TPI,Triose-Phosphate Isomerase,Triosephosphate Isomeras... |
Human | E. coli |
Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. TPI has been found in nearly every organism searched for the enzyme, including animals such as mammals and insects as well as in fungi, plants, and bacteria. However, some bacteria that do not perform glycolysis, like ureaplasmas, lack TPI. TPI plays an important role... | |||
TMPJ-00189 |
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
HAVCR2,Tim-3,TIM3,T cell immunoglobulin an... |
Cynomolgus | HEK293 Cells |
T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)extracellular domain (ECD), a 21 aa transmembrane segment, and a 78 aa cytoplasmic tail. TIM3 is up-regulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). Its binding to Galectin9 induces a range of immunosuppressive functions which enhance... | |||
TMPY-03424 |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (His)
hepatitis A virus cellular receptor 2,TIM-3,Tim... |
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is AAL65156.1. | |||
TMPY-01375 |
TIM-4/TIMD4 Protein, Mouse, Recombinant (His)
T-cell immunoglobulin and mucin domain containing 4,TIM<... |
Mouse | HEK293 Cells |
TIM-4/TIMD4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.3 kDa and the accession number is Q6U7R4. | |||
TMPK-01139 |
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 21-295, His)
KIM1,TIM-1,HAVCR-1,KIM-1,TIM,TIM1... |
Human | HEK293 Cells |
Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation. TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 21-295, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.58 kDa and the accession numb... | |||
TMPK-00189 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His & Avi), Biotinylated
TIM 3,HAVCR2,TIMD-3,TIM3,KIM3,CD3... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.8 kDa and the accession number is Q8TDQ0-1. | |||
TMPK-01141 |
TIM-4/TIMD4 Protein, Human, Recombinant (aa 25-314, His)
TIMD-4,TIMD4,TIM-4,TIM4 |
Human | HEK293 Cells |
Tim4 is a transmembrane protein as the phosphatidylserine (PS) receptor, known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed highly in macrophages, and macrophage Tim-4 inhibits inflammation under various conditions of immune activation. TIM-4/TIMD4 Protein, Human, Recombinant (aa 25-314, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 32.43 kDa and the accession number is Q96H15-1. | |||
TMPK-00546 |
TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)
CD365,HAVCR1,KIM1,TIMD-1,TIM-1,KIM-1,HAVcr... |
Cynomolgus | HEK293 Cells |
Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation. TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 35.25 kDa and the accession number is ... | |||
TMPY-03677 |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (hFc)
Tim3,TIM-3,hepatitis A virus cellular rece... |
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.9 kDa and the accession number is AAL65156.1. | |||
TMPK-00190 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His)
KIM3,TIM3,TIM 3,TIMD-3,HAVCR2, FL... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 20.7 kDa and the accession number is Q8TDQ0-1. | |||
TMPY-05463 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (mFc)
HAVCR2,TIM3,CD366,TIMD3,hepatitis A virus ... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.2 kDa and the accession number is Q8TDQ0-1. | |||
TMPY-01768 |
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His)
TIM1,HAVCR-1,KIM1,TIM,TIMD-1,hepa... |
Human | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is AAC39862.1. | |||
TMPY-01161 |
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His & hFc)
KIM1,HACVR,hepatitis A virus cellular receptor 1,TIM |
Human | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with hHis and Fc tag. The predicted molecular weight is 57 kDa and the accession number is AAC39862.1. | |||
TMPY-01173 |
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 1-135, His)
KIM-1,hepatitis A virus cellular receptor 1,HACVR,CD365,KIM1... |
Human | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 1-135, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.8 kDa and the accession number is AAC39862.1. | |||
TMPY-01244 |
TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His & hFc)
TIM-1,KIM-1,Tim1,Timd1,AI503787,h... |
Mouse | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with hHis and Fc tag. The predicted molecular weight is 49 kDa and the accession number is Q3V033. | |||
TMPY-05428 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc)
HAVcr-2,KIM-3,Tim-3,TIMD3,HAVCR2,TIM |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa and the accession number is Q8TDQ0-1. | |||
TMPY-06296 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
HAVcr-2,KIM-3,TIM3,CD366,HAVCR2,hepatitis A virus c... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 48.41 kDa and the accession number is Q8TDQ0-1. | |||
TMPJ-00423 |
TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His)
Hepatitis A virus cellular receptor 1 homolog,HAVcr-1,T cell... |
Mouse | HEK293 Cells |
TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hypera... | |||
TMPY-02124 |
TIM-4/TIMD4 Protein, Human, Recombinant (His)
SMUCKLER,T-cell immunoglobulin and mucin domain containing 4... |
Human | HEK293 Cells |
TIM-4/TIMD4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.7 kDa and the accession number is AAH08988.1. | |||
TMPJ-00599 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
TIM3,Hepatitis A virus cellular receptor 2,KIM-3,T-... |
Human | HEK293 Cells |
Hepatitis A virus cellular receptor 2(HAVCR2)is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4 (MIM 186940)-positive T ... | |||
TMPJ-00965 |
TIM16 Protein, S. cerevisiae, Recombinant
TIM16,Mitochondrial import inner membrane transloca... |
S. cerevisiae | E. coli |
Mitochondrial import inner membrane translocase subunit TIM16 (TIM16) is an ssential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM16 is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. TIM16 may act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase s... | |||
TMPJ-01087 |
TIM14 Protein, S. cerevisiae, Recombinant
Mitochondrial import inner membrane translocase subunit ... |
S. cerevisiae | E. coli |
Mitochondrial import inner membrane translocase subunit TIM14 (TIM14) is an essential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM14 is required to stimulate activity of mtHSP70 (SSC1). TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as p... | |||
TMPJ-00624 |
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)
Tim3,HAVcr-2,Timd3,Hepatitis A virus cellu... |
Marmoset | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession number is F7I881. | |||
TMPY-01350 |
TIM-1/KIM-1/HAVCR1 Protein, Canine, Recombinant (His)
hepatitis A virus cellular receptor 1 |
Canine | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession number is A0A8C0N5Y0. | |||
TMPY-01951 |
TIM-1/KIM-1/HAVCR1 Protein, Rhesus, Recombinant
hepatitis A virus cellular receptor 1 |
Rhesus | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is BAJ61041.1. | |||
TMPY-00553 |
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (hFc)
hepatitis A virus cellular receptor 2 |
Cynomolgus | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.4 kDa and the accession number is G7P6Q7. | |||
TMPY-01455 |
TIM-1/KIM-1/HAVCR1 Protein, Rat, Recombinant (His)
hepatitis A virus cellular receptor 1 |
Rat | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is O54947. | |||
TMPY-01671 |
TIM-1/KIM-1/HAVCR1 Protein, Rhesus, Recombinant (His)
hepatitis A virus cellular receptor 1 |
Rhesus | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is BAJ61041.1. | |||
TMPY-01317 |
TIM-1/KIM-1/HAVCR1 Protein, Rat, Recombinant (His & hFc)
hepatitis A virus cellular receptor 1 |
Rat | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Rat, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with hHis and Fc tag. The predicted molecular weight is 52.6 kDa and the accession number is O54947. | |||
TMPY-04280 |
TIM-1/KIM-1/HAVCR1 Protein, Canine, Recombinant (mFc)
hepatitis A virus cellular receptor 1 |
Canine | HEK293 Cells |
TIM-1/KIM-1/HAVCR1 Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41.8 kDa and the accession number is A0A8C0N5Y0. | |||
TMPJ-00174 |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
T-cell immunoglobulin mucin receptor 3,Hepatitis A virus cel... |
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-55 KDa and the accession number is Q8VIM0. | |||
TMPJ-00173 |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)
T-cell membrane protein 3,T-cell immunoglobulin and mucin do... |
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-50 KDa and the accession number is Q8VIM0. | |||
TMPH-01690 |
TIM14 Protein, Human, Recombinant (GST)
|
Human | E. coli |
Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity. | |||
TMPY-01107 |
TIMP-1 Protein, Human, Recombinant
EPO,TIMP metallopeptidase inhibitor 1,TIMP... |
Human | HEK293 Cells |
TIMP-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P01033. | |||
TMPH-01665 |
TIMP3 Protein, Human, Recombinant (His)
|
Human | E. coli |
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. | |||
TMPJ-00916 |
TIMP-2 Protein, Mouse, Recombinant (His)
metalloproteinase inhibitor 2,Tissue inhibitor of metallopro... |
Mouse | HEK293 Cells |
Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP‑1, TIMP‑2, TIMP‑3, and TIMP‑4. The TIMP-2 is detected in testis, retina, hippocampus and cerebral cortex. The function of TIMP 2 protein is to inhibit MMPs non covalently by the formation of binary complexes. Complexes with metalloproteinases (such as collagenases) and irreversi... | |||
TMPY-02912 |
TIMP-1 Protein, Rat, Recombinant
TIMP metallopeptidase inhibitor 1 |
Rat | HEK293 Cells |
TIMP-1 Protein, Rat, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.5 kDa and the accession number is P01860. | |||
TMPJ-00101 |
TIMP-2 Protein, Human, Recombinant (His)
Tissue Inhibitor of Metalloproteinases 2,TIMP2,CSC-... |
Human | HEK293 Cells |
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3, and TIMP-4. Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and i... | |||
TMPH-00784 |
Intimin Protein, Hafnia alvei, Recombinant (His & SUMO)
|
Hafnia alvei | E. coli |
Necessary for the production of attaching and effacing lesions on tissue culture cells. Intimin Protein, Hafnia alvei, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 46.1 kDa and the accession number is P52869. | |||
TMPY-01605 |
STIM1 Protein, Human, Recombinant (His)
stromal interaction molecule 1,TAM1,GOK,STRMK,IMD10,D11S4896... |
Human | HEK293 Cells |
Stromal interaction molecule 1, also known as STIM1 and GOK, is a cell membrane, a single-pass type I membrane protein and a endoplasmic reticulum membrane protein. STIM1 / GOK is ubiquitously expressed in various human primary cells and tumor cell lines. It contains one EF-hand domain and one SAM (sterile alpha motif) domain. STIM1 / GOK plays a role in mediating Ca2+influx following depletion of intracellular Ca2+stores. It acts as Ca2+sensor in the endoplasmic reticulum via its EF-hand domain... | |||
TMPH-00314 |
Lingual antimicrobial peptide Protein, Bubalus bubalis, Recombinant (His & KSI)
|
Bubalus bubalis | E. coli |
Has bactericidal activity. Lingual antimicrobial peptide Protein, Bubalus bubalis, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.8 kDa and the accession number is A3RJ36. | |||
TMPK-00093 |
TIMP-1 Protein, Mouse, Recombinant (hFc)
TPA-S1,CLGI,TIMP-1,EPO,TIMP,EPA,EPATIM... |
Mouse | HEK293 Cells |
Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner. | |||
TMPJ-01289 |
TIMP-4 Protein, Human, Recombinant (His)
TIMP4,TIMP-4,Metalloproteinase inhibitor 4... |
Human | HEK293 Cells |
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. | |||
TMPY-01485 |
TIMP-1 Protein, Mouse, Recombinant
Timp,EPA,Clgi,TIMP-1,TPA-S1,TIMP ... |
Mouse | HEK293 Cells |
TIMP-1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P12032. | |||
TMPH-01058 |
Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
CAP18,Cathelicidin antimicrobial peptide,CAMP,FALL3... |
Human | E. coli |
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 24.7 kDa and the accession number is P49913. | |||
TMPH-02782 |
TIMP4 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
TIMP4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli. | |||
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