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Search Results for " interleukin-3 "
Targets Recommended: Others

18

抑制剂 & 化合物

10

天然产物

95

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T21389 Enprofylline

Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum,恩丙茶碱

Others Others
Enprofylline (Enprofilina) 是具有选择性的 A2B 受体竞争性拮抗剂 (Ki:7 μM) ,也是磷酸二酯酶抑制剂。它可用于研究哮喘、慢性阻塞性肺疾病。
T9027 CA-4948

Emavusertib

IRAK; FLT Angiogenesis; Immunology/Inflammation; NF-κB; Tyrosine Kinase/Adaptors
CA-4948 (Emavusertib) 是一种IRAK4抑制剂,也是一种FLT3抑制剂,具有抗肿瘤作用。
T9537 N'-Nitro-D-arginine

N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸

Others Others
N'-Nitro-D-arginine (N'-Nitro-D-arginine) 是一种砌块。
T11670 IRAK inhibitor 3

IRAK Immunology/Inflammation; NF-κB
IRAK inhibitor 3 是白细胞介素-1受体相关激酶调节剂。
T4602 Hydrocortisone hemisuccinate

Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate

Glucocorticoid Receptor; Others; Interleukin Endocrinology/Hormones; Immunology/Inflammation; Others
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) 是糖皮质激素, 是口服有活性的甾体抗炎剂。它能够降低IL-6(IC50:6.7 μM)、IL-3(IC50:21.4 μM)的生物活性,可用于研究溃疡性结肠炎。
T7606 Guanosine 5'-diphosphate disodium salt

5'-二磷酸鸟苷二钠,5'-GDP-Na2,鸟苷-5'-二磷酸二钠盐

Endogenous Metabolite Metabolism
Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) 是一种核苷二磷酸。它是一种潜在的铁动员剂,能够阻断铁调素-铁转运蛋白相互作用,也可以调节白 IL-6/stat-3 途径。
T38105 Ixekizumab

LY2439821

IL Receptor; Interleukin Immunology/Inflammation
Ixekizumab (LY2439821) 是一种人源化 IgG4 单克隆抗体,可选择性结合和中和白细胞介素 IL-17A ,Kd 值<3 pM。Ixekizumab 科阻断 IL-17A 与 IL-17RA 的结合,但不与其他 IL-17 家族成员结合。Ixekizumab 用于治疗中重度斑块型银屑病、银屑病关节炎和牛皮癣。
T71857 GTP-14564

FLT; Tyrosine Kinases Angiogenesis; Tyrosine Kinase/Adaptors
GTP-14564是一种新型酪氨酸激酶抑制剂,对 wt-FLT3和ITD-FLT3也具有抑制作用。GTP-14564 在 3μ m 处抑制表达 ITD-FLT3 的白细胞介素-3 非依赖性 Ba/F1 的生长,而需要高 30 倍的 GTP-14564 浓度来抑制表达野生型 FLT3 的 Ba/F3 的 FLT3 配体依赖性生长 (wt-FLT3)。
T28599 Ro26-4550

Ro 26-4550,Ro-26-4550

Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).
T76771 Pivekimab

Pivekimab为针对白介素3(IL-3)及CD123的人源IgG1型单克隆抗体。适用于母细胞浆细胞样树突状细胞肿瘤(BPDCN)研究。
T71176 Atiprimod (free base)

Atiprimod is an orally bioavailable small molecule belonging to the azaspirane class of cationic amphiphilic agents with anti-inflammatory, antineoplastic, and antiangiogenic properties. Atiprimod inhibits the phosphorylation of signal transducer and activator of transcription 3 (STAT3), blocking the signalling pathways of interleukin-6 and vascular endothelial growth factor (VEGF) and downregulating the anti-apoptotic proteins Bcl-2, Bcl-XL, and Mcl-1, thereby inhibiting cell proliferation, ind...
T77141 Pegaldesleukin

Pegaldesleukin 是一种聚乙二醇与白细胞介素-2 的偶联物 (PEG-IL2)。Pegaldesleukin 具有抗病毒活性,在 HIV 中有潜在应用,可能通过保留免疫组库来延缓 HIV 感染的进展。
T76803 Elsilimomab

Elsilimomab (B-E8) 是一种抗白介素-6 (IL-6) 的 IgG1单克隆抗体,其 KD 为 22 pM,IC50为 1.4 nM。Elsilimomab 可用于多发性骨髓瘤、肾细胞癌和类风湿性关节炎 (RA) 的研究。
T72120 Guanosine 5'-diphosphate sodium

GDP sodium

Guanosine 5'-diphosphate (GDP) sodium 是一种核苷二磷酸,可激活 5'-三磷酸腺苷敏感的 K+通道。Guanosine 5'-diphosphate sodium 是一种潜在的铁动员剂,可阻断铁调素-铁转运蛋白 (hepcidin-ferroportin) 相互作用并调节 IL-6/stat-3通路。Guanosine 5'-diphosphate sodium 可用于炎症研究,如炎症性贫血 (AI)。
T73697 Denileukin diftitox

Denileukin diftitox (DAB 389IL-2) 是一种融合蛋白毒素,将白喉毒素 (DT) 与白细胞介素 2 (IL-2) 结合,专门针对表达高亲和力IL-2受体 (IL-2R)、CD25 的细胞。它通过与IL-2R阳性细胞结合并利用白喉毒素片段的内化作用来抑制蛋白质合成,从而达到耗尽目标细胞的效果。
T73852 Ac-YVAD-CHO acetate

Ac-YVAD-CHO(L-709049)醋酸盐是一种高效、可逆、特异的四肽白介素1β转化酶(ICE)抑制剂,小鼠和人类的Ki值分别为3.0 nM和0.76 nM。它同时也能抑制caspase-1,从而抑制成熟IL-lβ的产生。
T36668 Geranylgeranoic Acid

Geranylgeranoic acid (GGA) is an isoprenoid that has been found inS. chinensisand has anticancer activity.1It induces apoptosis in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes, but not primary mouse hepatocytes, when used at concentrations ranging from 1 to 20 μM. GGA (10 μM) induces apoptosis in Huh7 cellsvialoss of the mitochondrial membrane potential and activation of interleukin-1β-converting enzyme (ICE) and cysteine protease precursor 32 (CPP32).2It also...
T37604 ITK inhibitor

Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for the treatment of inflammation and immune-mediated disorders. ITK inhibitor (N-[5-[[3-[(4-Acetylpiperazin-1-yl)carbonyl]-4-methyl-6-methoxy-phenyl]thio]thiazol-2-yl]-4-(N-1,2-dimethylpropylaminome...

化合物

Enprofylline
Cat.No: T21389
Synonym: Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum,恩丙茶碱
Target: Others
CA-4948
Cat.No: T9027
Synonym: Emavusertib
Target: IRAK, FLT
N'-Nitro-D-arginine
Cat.No: T9537
Synonym: N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸
Target: Others
IRAK inhibitor 3
Cat.No: T11670
Synonym:
Target: IRAK
Hydrocortisone hemisuccinate
Cat.No: T4602
Synonym: Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate
Target: Glucocorticoid Receptor, Others, Interleukin
Guanosine 5'-diphosphate disodium salt
Cat.No: T7606
Synonym: 5'-二磷酸鸟苷二钠,5'-GDP-Na2,鸟苷-5'-二磷酸二钠盐
Target: Endogenous Metabolite
Ixekizumab
Cat.No: T38105
Synonym: LY2439821
Target: IL Receptor, Interleukin
GTP-14564
Cat.No: T71857
Synonym:
Target: FLT, Tyrosine Kinases
Ro26-4550
Cat.No: T28599
Synonym: Ro 26-4550,Ro-26-4550
Target:
Pivekimab
Cat.No: T76771
Synonym:
Target:
Atiprimod (free base)
Cat.No: T71176
Synonym:
Target:
Pegaldesleukin
Cat.No: T77141
Synonym:
Target:
Elsilimomab
Cat.No: T76803
Synonym:
Target:
Guanosine 5'-diphosphate sodium
Cat.No: T72120
Synonym: GDP sodium
Target:
Denileukin diftitox
Cat.No: T73697
Synonym:
Target:
Ac-YVAD-CHO acetate
Cat.No: T73852
Synonym:
Target:
Geranylgeranoic Acid
Cat.No: T36668
Synonym:
Target:
ITK inhibitor
Cat.No: T37604
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3829 Ginsenoside F3

人参皂苷F3

Others; IFNAR; Interleukin Immunology/Inflammation; Others
Ginsenoside F3 是一种皂苷,提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达,有免疫增强的作用。
TN1818 Kaempferol 3-O-β-D-glucuronide

Kaempferol-3-O-glucuronide,Kaempferol-3-beta-O-glucuronide,山奈酚葡萄糖醛酸苷,Kaempferol-3-glucuronide

IL Receptor Immunology/Inflammation
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide) 具有抗氧化活性。 类黄酮葡糖苷酸可以被来自各种人体细胞的微粒体 α2-葡糖苷酸酶解偶联。
T2893 Muscone

3-Methylcyclopentadecanone,Methylexaltone,麝香酮

MMP; TNF; NF-κB; NOD-like Receptor (NLR); P-gp; Interleukin Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB; Proteases/Proteasome
Muscone (3-Methylcyclopentadecanone) 是中药麝香的一种主要活性单体。它抑制NF-κB 和NLRP3炎性小体的活化,显著降低炎性细胞因子水平,并最终改善心脏功能和存活率。
TN1291 7,3',4'-Tri-O-methylluteolin

5-Hydroxy-3',4',7-trimethoxyflavone,木犀草素-7,3',4'-三甲醚

TNF; COX; Interleukin Apoptosis; Immunology/Inflammation; Neuroscience
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) 是来自草药马鞭草科的一种类黄酮,具有抗炎,解热,镇咳,抗糖尿病、抗癌和抗黑素生成特性。它以浓度依赖方式明显抑制促炎细胞因子,可显著降低在转录水平的诱导型一氧化氮合酶和环加氧酶-2 的 mRNA 表达。
T7210 Guanosine 5'-diphosphate

GDP,鸟苷-5ˊ-二磷酸

Endogenous Metabolite Metabolism
Guanosine 5'-diphosphate (GDP) 是核苷二磷酸,是潜在的铁动员剂,能够阻断铁调素-铁转运蛋白相互作用并调节白细胞介素-6 (IL-6)/stat-3 途径。
T3S0364 L-Arginine

L-精氨酸,L-Arg,(S)-(+)-Arginine

IL Receptor; Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism
L-Arginine (L-Arg) 是内皮型一氧化氮合酶(eNOS) 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞,并被代谢成一氧化氮、多胺或 L-脯氨酸。
T6S1579 Monotropein

水晶兰苷,Monotropeine

Others Others
Monotropein (Monotropeine) 是从Morinda officinalis 中获得,能够抑制硫酸葡聚糖硫酸钠诱导的结肠炎小鼠模型中炎性因子的表达。
T6S1597 Mulberroside A

桑皮苷 A,桑皮苷A

TNF; Tyrosinase; Interleukin Apoptosis; Immunology/Inflammation; Proteases/Proteasome
Mulberroside A 是桑中的一种主要活性成分,可降低TNF-α、IL-1β和IL-6的表达,抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化 。它抑制蘑菇酪氨酸酶,具有抗炎和抗细胞凋亡作用。
T2S2264 Linalool

Linalol,(±)-Linalool,Phantol,沉香醇

Apoptosis; IL Receptor; TNF; Endogenous Metabolite; iGluR Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
Linalool (Linalol) 是存在芫荽等植物中的单萜类天然产物,是竞争性NMDA 受体拮抗剂,具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤,具有镇痛、抗菌和抗炎的特性。
TN4490 Manassantin B

ERK; BCL; p38 MAPK; TNF; NF-κB; JNK; STAT; Antifection Apoptosis; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in pa...

天然产物

Ginsenoside F3
Cat.No: T3829
Synonym: 人参皂苷F3
Target: Others, IFNAR, Interleukin
Kaempferol 3-O-β-D-glucuronide
Cat.No: TN1818
Synonym: Kaempferol-3-O-glucuronide,Kaempferol-3-beta-O-glucuronide,山奈酚葡萄糖醛酸苷,Kaempferol-3-glucuronide
Target: IL Receptor
Muscone
Cat.No: T2893
Synonym: 3-Methylcyclopentadecanone,Methylexaltone,麝香酮
Target: MMP, TNF, NF-κB, NOD-like Receptor (NLR), P-gp, Interleukin
7,3',4'-Tri-O-methylluteolin
Cat.No: TN1291
Synonym: 5-Hydroxy-3',4',7-trimethoxyflavone,木犀草素-7,3',4'-三甲醚
Target: TNF, COX, Interleukin
Guanosine 5'-diphosphate
Cat.No: T7210
Synonym: GDP,鸟苷-5ˊ-二磷酸
Target: Endogenous Metabolite
L-Arginine
Cat.No: T3S0364
Synonym: L-精氨酸,L-Arg,(S)-(+)-Arginine
Target: IL Receptor, Endogenous Metabolite, NO Synthase
Monotropein
Cat.No: T6S1579
Synonym: 水晶兰苷,Monotropeine
Target: Others
Mulberroside A
Cat.No: T6S1597
Synonym: 桑皮苷 A,桑皮苷A
Target: TNF, Tyrosinase, Interleukin
Linalool
Cat.No: T2S2264
Synonym: Linalol,(±)-Linalool,Phantol,沉香醇
Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR
Manassantin B
Cat.No: TN4490
Synonym:
Target: ERK, BCL, p38 MAPK, TNF, NF-κB, JNK, STAT, Antifection
Cat. No. Product Name Species Expression System
TMPY-00095 IL-3 Protein, Human, Recombinant (His)

IL-3,interleukin 3,Interleuki...

Human HEK293 Cells
IL-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.5 kDa and the accession number is P08700.
TMPY-00297 IL-3 Protein, Human, Recombinant(aa 20-152)

interleukin 3,白介素,白细胞介素,Interleukin

Human E. coli
IL-3 Protein, Human, Recombinant(aa 20-152) is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is P08700.
TMPY-04845 IL-3 Protein, Mouse, Recombinant

Il-3,白介素,PSF,HCGF,BPA,白细胞介素,MCGF,Csfmu,interleu...

Mouse HEK293 Cells
IL-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.7 kDa and the accession number is P01586.
TMPY-01410 IL-3R alpha/CD123 Protein, Human, Recombinant (His)

CD123,interleukin 3 receptor, alp...

Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P26951-1.
TMPJ-00051 IL-3 Protein, Mouse, Recombinant (His)

Mast cell growth factor,Il3,Multipotential colony-s...

Mouse HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages.Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, bu...
TMPY-04236 IL-31RA Protein, Human, Recombinant (His)

CRL,CRL3,PRO21384,PLCA2,GLMR,interleuk...

Human HEK293 Cells
IL-31RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.2 kDa and the accession number is EAW54932.1.
TMPY-00093 IL-31RA Protein, Human, Recombinant (hFc)

CRL,CRL3,GLMR,PRO21384,hGLM-R,interleu...

Human HEK293 Cells
IL-31RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.5 kDa and the accession number is EAW54932.1.
TMPY-02772 IL-3 Protein, Rat, Recombinant (His)

白细胞介素,白介素,interleukin 3

Rat Baculovirus Insect Cells
IL-3 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.5 kDa and the accession number is P97688.
TMPY-06715 IL-3R alpha/CD123 Protein, Cynomolgus, Recombinant (His)

IL-3R α/CD123,interleukin 3

Cynomolgus HEK293 Cells
IL-3R alpha/CD123 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.25 kDa and the accession number is G8F3K3.
TMPY-04034 IL-3R alpha/CD123 Protein, Canine, Recombinant (His)

interleukin 3 receptor, alpha (low affinit...

Canine HEK293 Cells
IL-3R alpha/CD123 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is XP_851626.3.
TMPK-00655 IL-3 Protein, Cynomolgus, Recombinant (His)

MCGF,IL3,MULTI-CSF,IL-3MGC79398,<...

Cynomolgus E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 15.13 kDa and the acce...
TMPK-00590 IL-3 Protein, Human, Recombinant (E. coli)

interleukin-3,IL-3,MULTI-CSF,MCGF...

Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant(E. coli) is expressed in E. coli expression system. The predicted molecular weight is 15.09 kDa and the accession number is A...
TMPJ-01347 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His)

IL1RAP,Interleukin-1 Receptor Accessory Protein,IL-...

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-70 KDa and the accession number is Q9NPH3-2.
TMPK-00032 IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated

白细胞介素,白介素,interleukin-3,MULTI-CSF,IL-3...

Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 16....
TMPY-00076 IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc)

IL-3R α/CD123,interleukin 3

Mouse HEK293 Cells
IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.5 kDa and the accession number is P26952-1.
TMPK-00033 IL-3 Protein, Human, Recombinant (hFc)

IL3,interleukin-3,IL-3,M...

Human HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 41.6 kDa and the accession num...
TMPK-00031 IL-3 Protein, Human, Recombinant (His & Avi)

IL-3,IL3,IL-3MGC79398,白介...

Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 16.9 kDa and the ...
TMPK-00049 IL-3 Protein, Mouse, Recombinant (hFc)

IL3,MULTI-CSF,MCGF,白细胞介素,IL-3MGC793

Mouse HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.2 kDa and the accession num...
TMPJ-01346 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc & His)

IL-1RAcP,IL-1R3,IL1RAP,Interleukin-1 Recep...

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 80-100 KDa and the accession number is Q9NPH3-2.
TMPY-00592 IL-3R alpha/CD123 Protein, Mouse, Recombinant (His)

IL-3R α/CD123,interleukin 3

Mouse HEK293 Cells
IL-3R alpha/CD123 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and the accession number is EDL20630.1.
TMPY-05418 IL-3R alpha/CD123 Protein, Human, Recombinant (hFc)

IL3RX,IL-3R α/CD123,hIL-3

Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 59.8 kDa and the accession number is P26951-1.
TMPJ-00639 CD123 Protein, Cynomolgus, Recombinant (His)

Interleukin-3 receptor subunit α,IL-3<...

Cynomolgus HEK293 Cells
CD123 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is G8F3K3.
TMPJ-00251 IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His)

IL-3 receptor subunit alpha,IL-3R subunit ...

Mouse HEK293 Cells
IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His) is expressed in HEK293 mammalian cells with C-8xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is P26952.
TMPY-06744 IL-3R alpha/CD123 Protein, Human, Recombinant (hFc & Avi), Biotinylated

IL3RX,IL3RAY,interleukin 3

Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 61.62 kDa and the accession number is NP_002174.1.
TMPY-06793 IL-3R alpha/CD123 Protein, Human, Recombinant (His & Avi), Biotinylated

interleukin 3 receptor, alpha (low affinit...

Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 36.34 kDa and the accession number is NP_002174.1.
TMPJ-00244 IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated

IL-3R subunit α,IL-3RA,Interleukin

Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 80-100 KDa and the accession number is P26951.
TMPJ-00076 IL-28B Protein, Human, Recombinant

IL-28C,IFN-λ-4,IFNL4,Interferon λ-4,IL28B,IL-28B,Interle...

Human HEK293 Cells
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed...
TMPJ-00387 IL-4R alpha Protein, Mouse, Recombinant (hFc)

Soluble IL-4R-alpha,Interleukin-4 receptor subunit ...

Mouse HEK293 Cells
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ...
TMPK-00242 IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated

IL3RAY,IL-3R subunit alpha,IL-3 R...

Human HEK293 Cells
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.
TMPH-03116 IL-4R Protein, Pig, Recombinant (His)

Sus scrofa (Pig) E. coli
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. IL-4R Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted mo...
TMPK-01378 IL-12B Protein, Cynomolgus, Recombinant (His)

CLMF2,NKSF2,CLMF,CLMF p40,IL-12B,IL-12 subunit p40,NKS

Cynomolgus HEK293 Cells
Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studi...
TMPY-06986 FGF-8b Protein, Human, Recombinant

NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-00132 Mesothelin Protein, Human, Recombinant

MPF,SMRP,Mesothelin

Human HEK293 Cells
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His)

MER6,CD47 molecule,IAP,OA3

Human HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc)

Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated

CD47 molecule,MER6,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-04683 CD47 Protein, Human, Recombinant

MER6,CD47 molecule,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His)

AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His)

PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...

Human HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His)

NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01897 PRSS3 Protein, Human, Recombinant (His)

PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...

Human HEK293 Cells
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His)

L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

interleukin-15 receptor subunit α,IL15RA,interl...

Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-01180 CD86 Protein, Human, Recombinant (His)

CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72

Human HEK293 Cells
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPY-05353 CCL26 Protein, Human, Recombinant

MIP-4alpha,SCYA26,MIP-4a,chemokine (C-C motif) ligand 26,IMA...

Human Baculovirus Insect Cells
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3), which is also expressed by several different cell types, including basophils, dendritic cells, smooth muscle cells, epithelial cells and fibroblasts. The sequence similarity between the three eotaxins is limited (<4%), but their functional properties are very similar. Eotaxin-1 ...
TMPJ-00177 BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated

BAFF,Dendritic cell-derived TNF-like molecule,CD257,B lympho...

Human HEK293 Cells
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). BAFF can promotes the survival, proliferation and maturation of B lymphocytes, which are key elements in the pathogenesis of systemic lupus erythematosus (SLE). This cytokine is encoded on TNFSF13B gene, and diverse single-nucleotide polymor...
TMPY-04421 FES Protein, Human, Recombinant (His & GST)

FPS,FES proto-oncogene, tyrosine kinase

Human Baculovirus Insect Cells
Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and oneSH2 domain. FES is a non-receptor protein tyrosine kinase expressed in hematopoietic progenitors and differentiated myeloid cells. FES is observed in the nuclear, granular and plasma membrane fractions of primary human neutrophils and the myeloid leukemia cell line, HL-6. T...
TMPJ-00274 LTBR Protein, Human, Recombinant (His)

TNFCR,Tumor Necrosis Factor Receptor Superfamily Member ...

Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand p...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His)

TRASK,CD318,CUB domain containing protein 1,SIMA1

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
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重组蛋白

IL-3 Protein, Human, Recombinant (His)
Cat.No: TMPY-00095
Species: Human
Expression System: HEK293 Cells
IL-3 Protein, Human, Recombinant(aa 20-152)
Cat.No: TMPY-00297
Species: Human
Expression System: E. coli
IL-3 Protein, Mouse, Recombinant
Cat.No: TMPY-04845
Species: Mouse
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
Cat.No: TMPY-01410
Species: Human
Expression System: HEK293 Cells
IL-3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00051
Species: Mouse
Expression System: HEK293 Cells
IL-31RA Protein, Human, Recombinant (His)
Cat.No: TMPY-04236
Species: Human
Expression System: HEK293 Cells
IL-31RA Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00093
Species: Human
Expression System: HEK293 Cells
IL-3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02772
Species: Rat
Expression System: Baculovirus Insect Cells
IL-3R alpha/CD123 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-06715
Species: Cynomolgus
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Canine, Recombinant (His)
Cat.No: TMPY-04034
Species: Canine
Expression System: HEK293 Cells
IL-3 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00655
Species: Cynomolgus
Expression System: E. coli
IL-3 Protein, Human, Recombinant (E. coli)
Cat.No: TMPK-00590
Species: Human
Expression System: E. coli
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His)
Cat.No: TMPJ-01347
Species: Human
Expression System: HEK293 Cells
IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00032
Species: Human
Expression System: E. coli
IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00076
Species: Mouse
Expression System: HEK293 Cells
IL-3 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00033
Species: Human
Expression System: HEK293 Cells
IL-3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00031
Species: Human
Expression System: E. coli
IL-3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00049
Species: Mouse
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-01346
Species: Human
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00592
Species: Mouse
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05418
Species: Human
Expression System: HEK293 Cells
CD123 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00639
Species: Cynomolgus
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His)
Cat.No: TMPJ-00251
Species: Mouse
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06744
Species: Human
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06793
Species: Human
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated
Cat.No: TMPJ-00244
Species: Human
Expression System: HEK293 Cells
IL-28B Protein, Human, Recombinant
Cat.No: TMPJ-00076
Species: Human
Expression System: HEK293 Cells
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00387
Species: Mouse
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated
Cat.No: TMPK-00242
Species: Human
Expression System: HEK293 Cells
IL-4R Protein, Pig, Recombinant (His)
Cat.No: TMPH-03116
Species: Sus scrofa (Pig)
Expression System: E. coli
IL-12B Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01378
Species: Cynomolgus
Expression System: HEK293 Cells
FGF-8b Protein, Human, Recombinant
Cat.No: TMPY-06986
Species: Human
Expression System: E. coli
Mesothelin Protein, Human, Recombinant
Cat.No: TMPY-00132
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His)
Cat.No: TMPY-04935
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03763
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05191
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant
Cat.No: TMPY-04683
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His)
Cat.No: TMPY-00072
Species: Human
Expression System: HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01020
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00892
Species: Human
Expression System: HEK293 Cells
PRSS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01897
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
Cat.No: TMPY-05748
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04142
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-01099
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His)
Cat.No: TMPY-01180
Species: Human
Expression System: HEK293 Cells
CCL26 Protein, Human, Recombinant
Cat.No: TMPY-05353
Species: Human
Expression System: Baculovirus Insect Cells
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
Cat.No: TMPJ-00177
Species: Human
Expression System: HEK293 Cells
FES Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04421
Species: Human
Expression System: Baculovirus Insect Cells
LTBR Protein, Human, Recombinant (His)
Cat.No: TMPJ-00274
Species: Human
Expression System: HEK293 Cells
CDCP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04298
Species: Human
Expression System: HEK293 Cells
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