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Search Results for " cb "

Targets Recommended: p97

346

抑制剂 & 化合物

10

天然产物

44

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6796	CB-5083 CB5083,CB 5083	p97	Ubiquitination
	CB-5083 是一种有效的、选择性的、可口服的 p97 AAA ATPase 抑制剂，IC50为 11 nM。
T41230	CB 65	Cannabinoid Receptor	GPCR/G Protein
	CB 65 是一种高亲和力和选择性的 CB2 受体激动剂，对 CB2 和 CB1 受体的 Kivalues 分别为 3.3 和 > 1000 nM。
T10693	CB-6644	Others	Others
	CB-6644 是 RUVBL1/2的选择性复合体抑制剂，能够抑制 RUVBL1/2 的 ATP 酶活性(IC50:15 nM)。它具有抗癌作用。
T60193	CB-5339	p97	Ubiquitination
	p97-IN-1 是有效的p97抑制剂，IC50<30 nM。
T14880	CB-7921220 6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid,6-(4-Aminostyryl)picolinic acid,6-[(E)-2-(4-aminophenyl)ethenyl]pyridine-2-carboxylic acid	AChR	Neuroscience
	CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid)是一种腺苷酸环化酶的抑制剂。
T25209	CB29 CB-29,CB 29	Dehydrogenase	Metabolism
	CB29 是醛脱氢酶 3A1 (ALDH3A1) 的特异性抑制剂。
T12246	CB-103	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	CB-103 是口服具有活性的蛋白相互作用抑制剂，靶向 NOTCH 转录复合体，具有抗肿瘤作用。
T6797	Telaglenastat CB 839,CB839,CB-839	transporter; Glutaminase; Autophagy	Autophagy; Metabolism; Proteases/Proteasome
	Telaglenastat (CB 839) 是一种选择性可逆的，有口服活性的谷氨酰胺酶 1 (GLS1) 抑制剂，抑制 GLS1剪接变异体 KGA 和 GAC，比 GLS2 具有更高的选择性。它可诱导细胞自噬，具有抗肿瘤活性。它对小鼠类肾和脑中的内源性谷氨酰胺酶的 IC50值分别为 23 nM 和 28 nM。
T1754	ZM 306416 CB 676475	VEGFR; Bcr-Abl; Src	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	ZM 306416 (CB 676475) 是一种 VEGFR 的有效抑制剂，能够抑制 KDR (IC50:0.1 μM) 和 Flt (IC50:2 μM)，也是一种 EGFR 的抑制剂(IC50<10 nM)。
T30765	CB 966 CB-966,CB966
	CB 966 is a bio-active chemical.
T30761	CB 3703 CB3703,NSC 289522,CB-3703
	CB 3703 is an inhibitor of dihydrofolate reductase and thymidylate synthase.
T23863	CB-6673567 CB 6673567
	CB-6673567 is a selective inhibitor of adenylyl cyclase.
T30760	CB 30900 CB30900,CB-30900
	CB30900 is a novel and effective thymidylate synthase inhibitor.
T30764	CB 3988 CB3988,CB-3988
	CB 3988 is a bio-active chemical.
T30763	CB 3731 CB3731,CB-3731
	CB 3731 is used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase.
T30768	CB-403 UNII-4V9Q0C88UK,CB403,CB 403
	CB-403 is a cinnamaldehyde derivative that has antitumor effects by blocking cell cycle progression in the G2/M phase.
T30769	CB-7646 CB 7646,UNII-LYO93N5MEB
	CB-7646 is a stable trimelamol (TM) analogue, which is an antitumor agent.
T30762	CB 3705 CB3705,CB-3705,5,8-Dideazafolic acid
	CB 3705 is a bio-active chemical.
T14551	Bevenopran CB-5945,ADL-5945	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Bevenopran (CB-5945) is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.
T30759	CB 1837 CB1837,CB-1837,AI3-51871,NSC 3375
	CB 1837 is an anti-tumour agent.
T6216	Abiraterone 阿比特龙,CB-7598	P450	Metabolism
	Abiraterone (CB-7598) 是不可逆的CYP17A1抑制剂，具有抗雄激素作用，抑制细胞色素 p450 酶 CYP17 的 17α-羟化酶 (IC50:2.5 nM) 和 17,20-裂合酶 (IC50:15 nM) 活性。
T30767	CB-181963 CB 181963,CB181963,UNII-6784994L0W,CAB 175
	CB-181963, a new cephalosporin, is an effective antistaphylococcal drug, showing excellent activity against the resistance of MRSA strains to other cephalosporins in planktonic and biofilm cultures.
T25208	CB 3717 CB3717,CB-3717,N(sup 10)-Propargyl-5,8-dideazafolic acid
	CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.
T5842	Bromocriptine mesylate 甲磺酸溴隐亭,CB-154	Dopamine Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Bromocriptine mesylate (CB-154) 是一种有效的多巴胺受体激动剂，以最高的亲和力结合 D2 受体，Ki 为 2.5 nM。
T69426	CB-83
	CB-83 is a novel G6PD inhibitor.
T10692	CB-1158 dihydrochloride (2095732-06-0 free base) INCB01158 dihydrochloride,CB-1158 dihydrochloride	Others	Others
	CB-1158 dihydrochloride is an effective and orally active inhibitor of arginase (IC50s: 86 nM and 296 nM for recombinant human arginase 1 and 2).
T72011	CB-892
	CB-892 is a novel inhibitor of hiv-1 gene expression
T0975	Chlorambucil CB-1348,Chloroambucil,苯丁酸氮芥,WR-139013	DNA Alkylator/Crosslinker; DNA Alkylation	DNA Damage/DNA Repair
	Chlorambucil (CB-1348) 是一种口服活性的氮芥类双功能烷基化剂，具有抗肿瘤活性，可用于研究淋巴细胞白血病、卵巢癌和乳腺癌以及霍奇金病。
T70427	CB-64D
	CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.
T0996	Ethynodiol diacetate Ethynodiol acetate,双醋炔诺醇,8080 CB	Estrogen/progestogen Receptor; Progesterone Receptor	Endocrinology/Hormones; Others
	Ethynodiol diacetate (Ethynodiol acetate) 是一种可用作激素避孕药的甾体孕激素，具有相对较少或没有雄激素效果，而具有显著雌激素作用。
T14879	CB 300919	Others	Others
	CB 300919 is a quinazoline-based antitumor agent with high activity in the CH1 human ovarian tumor xenograft and has continuous exposure (96 h) growth inhibition (IC50: 2 nM).
T37075	CB2R PAM Ec2la	Cannabinoid Receptor	GPCR/G Protein
	CB2R PAM 是一种口服活性大麻素 2 型受体（CB2Rs）阳性突变调节剂，它能增强 CP 55940 和 2-Arachidonylglycerol 刺激的 [35S]GTPγS 与 CB2 受体的结合，但在没有激动剂的情况下没有作用。CB2R PAM 在神经病理性疼痛小鼠模型中显示出抗损伤活性。
T10696	CB2 modulator 1	Cannabinoid Receptor	GPCR/G Protein
	CB2 modulator 1 是一种有效的 CB2 调节剂。可用于免疫疾病、骨质疏松症、炎症、肾缺血的研究。
T70928	CB-1158-analog
	CB-1158-analog, also known as Numidargistat-analog and INCB01158-analog, is a potent and orally active arginase inhibitor with IC50=89 nM) . CB-1158 blocked myeloid cell-mediated suppression of T cell proliferation in vitro and reduced tumor growth in multiple mouse models of cancer, as a single agent and in combination with checkpoint blockade, adoptive T cell therapy, adoptive NK cell therapy, and the chemotherapy agent gemcitabine. CB-1158 increased tumor-infiltrating CD8+ T cells and NK cell...
T14881	CB1 antagonist 2 AM4113	Cannabinoid Receptor	GPCR/G Protein
	CB1 antagonist 2 (AM4113) 是一种 caimabinoid 1 拮抗剂，在体内抑制 CB1 的IC50值为 25.5 nM。
T10694	CB1 inverse agonist 1 MRL-650	Cannabinoid Receptor	GPCR/G Protein
	CB1 inverse agonist 1 (MRL-650) 是一种具有口服活性和选择性的 CB1 激动剂。 CB1 和 CB2 的 IC50 分别为 7.5 nM 和 4100 nM。 CB1 inverse agonist 1 显示出厌食作用。
T23608	Acequinoline CB 4985,CB4985,CB-4985
	Acequinoline is an analgesic with certain antihistamine properties.
T5996	CB1-IN-1 DBPR211,1-(2,4-二氯苯基)-N-1-哌啶基-4-[[(1-吡咯烷基磺酰基)氨基]甲基]-5-[5-[2-[4-(三氟甲基)苯基]乙炔基]-2-噻吩基]-1H-吡唑-3-甲酰胺	Cannabinoid Receptor	GPCR/G Protein
	CB1-IN-1 (DBPR211) 是新型的外周大麻素-1受体 (CB1R) 拮抗剂，作用于CB1R (EC50 = 3 nM) 和 CB2R 的Ki 分别为0.3 nM 和 21 nM。
T125963	Psi Cb

T63376	CB 168
	CB 168是有效的靶向异亮基 tRNA 合成酶 (IleRS) 选择性氨基酰基氨基酰芳基四唑抑制剂。
T78083	CB-25	Cannabinoid Receptor	GPCR/G Protein
	CB-25是一种CB1大麻素受体的部分激动剂配体。它能增强Forskolin诱导的癌细胞中cAMP的形成，但在Forskolin诱导的hCB1-CHO细胞中则不显示增强作用。
T6215	Abiraterone Acetate Zytiga,乙酸阿比特龙酯,CB7630	P450	Metabolism
	Abiraterone Acetate (CB7630) 是一种具有口服活性的、不可逆的 CYP17A1选择性抑制剂，具有抗雄激素作用。它是 Abiraterone 的前药。
T25242	Chlornaphazine CB 1048,CB-1048,R 48,Erysan,CB1048
	Chlornaphazine is an antineoplastic and has been identified as a human carcinogen.
T10692L	Numidargistat INCB01158,CB-1158	Others	Others
	CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).
T19646	Altizide CB-8093,Aldactacine,P 1779,CB 8093,P1779,P-1779
	Altizide is a thiazide diuretic. It is used to treat oedema and hypertension.
T6798	Tretazicar 5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829	DNA Alkylator/Crosslinker; DNA Alkylation	DNA Damage/DNA Repair
	Tretazicar (NSC-115829) 是一种抗肿瘤前药，由 NAD(P)H 醌氧化还原酶 2 激活。它在酶促活化后生成细胞毒性双功能烷基剂，可以形成 DNA-DNA 链间交联。
T69488	CB5255829
	CB5255829 is a novel inhibitor of Mycobacterium marinum MelF (Rv1936), exhibiting bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro.
T71846	CB6513745
	CB6513745 is a novel inhibitor of Mycobacterium marinum MelF (Rv1936), exhibiting bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro.
T39309	Telaglenastat hydrochloride CB-839 hydrochloride
	Telaglenastat (CB-839) hydrochloride is a first-in-class, reversible, and orally active inhibitor of glutaminase 1 (GLS1). It selectively inhibits the splice variants of GLS1, specifically KGA (kidney-type glutaminase) and GAC (glutaminase C), as compared to GLS2. Telaglenastat hydrochloride has an IC50 of 23 nM for endogenous glutaminase in mouse kidney and 28 nM in the brain. In addition, it induces autophagy and exhibits antitumor activity.
T31269	Deazaminopterin CB-3702,CB3702,NCS-529860,CB 3702,NCS 529860
	Deazaminopterin is a bioactive chemical.

化合物

Cat.No: T6796

Synonym: CB5083,CB 5083

Target: p97

Cat.No: T41230

Target: Cannabinoid Receptor

Cat.No: T10693

Target: Others

Cat.No: T60193

Target: p97

Cat.No: T14880

Synonym: 6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid,6-(4-Aminostyryl)picolinic acid,6-[(E)-2-(4-aminophenyl)ethenyl]pyridine-2-carboxylic acid

Target: AChR

Cat.No: T25209

Synonym: CB-29,CB 29

Target: Dehydrogenase

Cat.No: T12246

Target: Gamma-secretase

Cat.No: T6797

Synonym: CB 839,CB839,CB-839

Target: transporter, Glutaminase, Autophagy

Cat.No: T1754

Synonym: CB 676475

Target: VEGFR, Bcr-Abl, Src

Cat.No: T30765

Synonym: CB-966,CB966

Cat.No: T30761

Synonym: CB3703,NSC 289522,CB-3703

Cat.No: T23863

Synonym: CB 6673567

Cat.No: T30760

Synonym: CB30900,CB-30900

Cat.No: T30764

Synonym: CB3988,CB-3988

Cat.No: T30763

Synonym: CB3731,CB-3731

Cat.No: T30768

Synonym: UNII-4V9Q0C88UK,CB403,CB 403

Cat.No: T30769

Synonym: CB 7646,UNII-LYO93N5MEB

Cat.No: T30762

Synonym: CB3705,CB-3705,5,8-Dideazafolic acid

Cat.No: T14551

Synonym: CB-5945,ADL-5945

Target: Opioid Receptor

Cat.No: T30759

Synonym: CB1837,CB-1837,AI3-51871,NSC 3375

Cat.No: T6216

Synonym: 阿比特龙,CB-7598

Target: P450

Cat.No: T30767

Synonym: CB 181963,CB181963,UNII-6784994L0W,CAB 175

Cat.No: T25208

Synonym: CB3717,CB-3717,N(sup 10)-Propargyl-5,8-dideazafolic acid

Bromocriptine mesylate

Cat.No: T5842

Synonym: 甲磺酸溴隐亭,CB-154

Target: Dopamine Receptor, Autophagy

Cat.No: T69426

CB-1158 dihydrochloride (2095732-06-0 free base)

Cat.No: T10692

Synonym: INCB01158 dihydrochloride,CB-1158 dihydrochloride

Target: Others

Cat.No: T72011

Cat.No: T0975

Synonym: CB-1348,Chloroambucil,苯丁酸氮芥,WR-139013

Target: DNA Alkylator/Crosslinker, DNA Alkylation

Cat.No: T70427

Ethynodiol diacetate

Cat.No: T0996

Synonym: Ethynodiol acetate,双醋炔诺醇,8080 CB

Target: Estrogen/progestogen Receptor, Progesterone Receptor

Cat.No: T14879

Target: Others

Cat.No: T37075

Synonym: Ec2la

Target: Cannabinoid Receptor

CB2 modulator 1

Cat.No: T10696

Target: Cannabinoid Receptor

Cat.No: T70928

CB1 antagonist 2

Cat.No: T14881

Synonym: AM4113

Target: Cannabinoid Receptor

CB1 inverse agonist 1

Cat.No: T10694

Synonym: MRL-650

Target: Cannabinoid Receptor

Cat.No: T23608

Synonym: CB 4985,CB4985,CB-4985

Cat.No: T5996

Synonym: DBPR211,1-(2,4-二氯苯基)-N-1-哌啶基-4-[[(1-吡咯烷基磺酰基)氨基]甲基]-5-[5-[2-[4-(三氟甲基)苯基]乙炔基]-2-噻吩基]-1H-吡唑-3-甲酰胺

Target: Cannabinoid Receptor

Cat.No: T125963

Cat.No: T63376

Cat.No: T78083

Target: Cannabinoid Receptor

Abiraterone Acetate

Cat.No: T6215

Synonym: Zytiga,乙酸阿比特龙酯,CB7630

Target: P450

Cat.No: T25242

Synonym: CB 1048,CB-1048,R 48,Erysan,CB1048

Cat.No: T10692L

Synonym: INCB01158,CB-1158

Target: Others

Cat.No: T19646

Synonym: CB-8093,Aldactacine,P 1779,CB 8093,P1779,P-1779

Cat.No: T6798

Synonym: 5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829

Target: DNA Alkylator/Crosslinker, DNA Alkylation

Cat.No: T69488

Cat.No: T71846

Telaglenastat hydrochloride

Cat.No: T39309

Synonym: CB-839 hydrochloride

Deazaminopterin

Cat.No: T31269

Synonym: CB-3702,CB3702,NCS-529860,CB 3702,NCS 529860

Cat. No.	Product Name	Target	Signaling Pathways
T3S0738	yangonin Y100550,甲氧醉椒素	Cannabinoid Receptor; NF-κB; Autophagy	Autophagy; GPCR/G Protein; NF-κB
	Yangonin (Y100550) 是一种新型 CB1 受体配体，对人重组 CB1 受体具有亲和力。它可能是干预 NF-κB 依赖性病理状况的候选药物。
TN2268	Tetrahydromagnolol	Cannabinoid Receptor; GPR; GABA Receptor	Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Tetrahydromagnolol 是 Magnolol 的主要代谢产物，是一种弱的GPR55受体拮抗剂。它是选择性大麻素CB2受体激动剂，EC50为 170 nM，Ki 为 416 nM，对CB2受体的选择性比 CB1 受体高 20 倍。
TN7224	2,2'-Dihydroxy chalcone	Antibacterial; Autophagy	Autophagy; Microbiology/Virology
	2,2'-Dihydroxy chalcone 是一种用 fMLP/CB 刺激的大鼠中性粒细胞释放β-葡糖醛酸酶（IC50=1.6±0.2μM）和溶菌酶（IC50=1.4±0.2μM）的有效抑制剂。2,2'-Dihydroxy chalcone 对大肠杆菌、福氏志贺氏菌、白葡萄球菌和金黄色葡萄球菌有抑菌活性。
TN2286	Tsugaric acid A	NO Synthase	Immunology/Inflammation
	Tsugaric acid A 能够显著抑制超氧阴离子的形成，还可以保护人类角质形成细胞，使其免受紫外线 B 诱导的损害。
T5S1897	Linderalactone	Apoptosis; Others; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells
	Linderalactone 是从乌药中分离出来的一种倍半萜烯内酯，通过调节凋亡相关蛋白的表达和抑制 JAK/STAT 信号通路来抑制癌细胞生长。它以 IC50值为 15 µM 来抑制肺癌 A-549 细胞的增殖。
TN2408	Evofolin B	Cannabinoid Receptor	GPCR/G Protein
	Evofolin B 是从Zanthoxylum ailanthoides 的茎皮中分离出来的天然化合物。Evofolin B 对人类中性粒细胞对甲酰-L-蛋氨酸-L-亮氨酸-L-苯丙氨酸/cytochalasin B（fMLP/CB）产生的超氧阴离子有抑制作用。
TN4738	Paniculoside I FS-8855
	Paniculoside I(FS-8855) 是一种来自Pseudocaryopteris paniculata（CB Clarke）PD Cantino的酰化环烯醚醚萜葡萄糖苷。
TN2973	3'-O-Methylmurraol
	3'-O-Methylmurraol may have potential anti-inflammatory activity, it exhibits inhibition (IC50 ≤ 7.31 ug/mL) of superoxide anion generation by human neutrophils in response to formyl-l-methionyl-l-leucyl-l-phenylalanine/cytochalasin B (fMLP/CB).
TN1556	Decarine	Antifection	Microbiology/Virology
	Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL.
TN2766	2'-Hydroxydaidzein	Cannabinoid Receptor; Antioxidant	GPCR/G Protein; oxidation-reduction
	2'-Hydroxydaidzein 是一种在植物中发现的异黄酮类植物素，是一种天然化合物。2'-Hydroxydaidzein 具有抗氧化活性，主要由o -氢键解离焓(BDE)和氢原子转移(HAT)机制驱动。2'-Hydroxydaidzein 抑制炎症细胞中的化学介质，可能对治疗和预防与化学介质产生过多有关的中枢和外周炎症性疾病有作用。2'-Hydroxydaidzein 对大鼠中性粒细胞和formyl-Met-Leu-Phe/cytochalasin B（fMLP/CB）的释放具有抑制作用，IC（50）值分别为2.8+/-0.1和5.9+/-1.4 microM。

天然产物

Cat.No: T3S0738

Synonym: Y100550,甲氧醉椒素

Target: Cannabinoid Receptor, NF-κB, Autophagy

Tetrahydromagnolol

Cat.No: TN2268

Target: Cannabinoid Receptor, GPR, GABA Receptor

2,2'-Dihydroxy chalcone

Cat.No: TN7224

Target: Antibacterial, Autophagy

Tsugaric acid A

Cat.No: TN2286

Target: NO Synthase

Cat.No: T5S1897

Target: Apoptosis, Others, JAK

Cat.No: TN2408

Target: Cannabinoid Receptor

Cat.No: TN4738

Synonym: FS-8855

3'-O-Methylmurraol

Cat.No: TN2973

Cat.No: TN1556

Target: Antifection

2'-Hydroxydaidzein

Cat.No: TN2766

Target: Cannabinoid Receptor, Antioxidant

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-06623	CB2/CNR2 Protein, Human, Recombinant CB2,CB-2,CX5	Human	HEK293 Cells
	Genetic variants within the CNR2 gene encoding the cannabinoid receptor CB2 are associated with osteoporosis and low bone mineral density (BMD) in case-control studies. There is a possibility that genetic variants of the CNR1 gene may produce a liability to the complication of psychotic state after abuse of methamphetamine.
TMPY-02144	Cathepsin B Protein, Mouse, Recombinant (His) cathepsin B,CB	Mouse	HEK293 Cells
	Cathepsin B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.6 kDa and the accession number is P10605.
TMPH-03256	CNR1 Protein, Rat, Recombinant (His) Skr6,Brain-type cannabinoid receptor,Cannabinoid receptor 1,...	Rat	E. coli
	CNR1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 58.9 kDa and the accession number is P20272.
TMPH-01035	CNR1 Protein-VLP, Human, Recombinant (His) Cnr1,Skr6,CB1,CB-R,Cannabinoid receptor 1,...	Human	HEK293 Cells
	CNR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 54.6 kDa and the accession number is P21554.
TMPH-02098	PPP1CB Protein, Human, Recombinant (His)	Human	E. coli
	PPP1CB Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-01066	MICB Protein, Human, Recombinant (His) MHC class I polypeptide-related sequence B,PERB11.2	Human	HEK293 Cells
	MICB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is A0A7D9H7X8.
TMPK-00245	MICB Protein, Human, Recombinant (His & Avi) PERB11.2,MICB,MIC-B	Human	HEK293 Cells
	MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. MICB Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The ...
TMPY-03867	CBR3 Protein, Human, Recombinant (His) SDR21C2,carbonyl reductase 3,hCBR3,HEL-S-25	Human	E. coli
	CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has lo...
TMPY-03853	DCBLD2 Protein, Human, Recombinant (His) CLCP1,discoidin, CUB and LCCL domain containing 2,ESDN	Human	HEK293 Cells
	DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor med...
TMPY-03400	DCBLD1 Protein, Human, Recombinant (His) dJ94G16.1,discoidin, CUB and LCCL domain containing 1,RP1-94...	Human	HEK293 Cells
	Discoidin, also known as DCBLD1, contains 1 CUB domain, 1 F5/8 type C domain and 1 LCCL domain. It is a 715 amino acid single-pass membrane protein. Discoidin has a discoidin I-like domain which shares a common C-terminal region of about 110 amino acids with the FA58C domain, but whose N-terminal 40 amino acids are much less conserved. Discoidin gene contains 31 distinct gt-ag introns. Transcription produces 18 different mRNAs, 16 alternatively spliced variants and 2 unspliced forms. Discoidin i...
TMPH-02615	CBS Protein, Mouse, Recombinant (His) Cystathionine beta-synthase,Serine sulfhydrase,Beta-thionase...	Mouse	E. coli
	Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.
TMPH-01787	NCBP2 Protein, Human, Recombinant (GST)	Human	E. coli
	NCBP2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 44.9 kDa and the accession number is P52298.
TMPH-03433	ACB1 Protein, S. cerevisiae, Recombinant (His) Acyl-CoA-binding protein	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. ACB1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 12.1 kDa and the accession number is P31787.
TMPY-03417	ACBD7 Protein, Human, Recombinant (His) acyl-CoA binding domain containing 7,ACBD7,bA455B2....	Human	E. coli
	ACBD7, acyl-CoA-binding domain-containing protein 7, is a small (1 Kd) protein that contains 1 ACB (acyl-CoA-binding) domain. The ACB domain consists of four alpha-helices arranged in a bowl shape with a highly exposed acyl-CoA-binding site. The ligand is bound through specific interactions with residues on the protein, most notably several conserved positive charges that interact with the phosphate group on the adenosine-3'phosphate moiety, and the acyl chain is sandwiched between the hydrop...
TMPK-00247	MICB Protein, Human, Recombinant (hFc) MIC-B,PERB11.2,MICB	Human	HEK293 Cells
	MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. MICB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted ...
TMPY-03392	CKAP1/TBCB Protein, Human, Recombinant (His) CKAPI,tubulin folding cofactor B,CG22,CKAP1	Human	E. coli
	Tubulin-folding cofactor B, also known as TBCB, belongs to the TBCB family. It contains 1 CAP-Gly domain and can be detected in most tissues. TBCB binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway. The cytoskeleton is composed of 3 structural elements: actin filaments, microtubules, and intermediate filaments. TBCB is involved in regulation of tubulin heterodimer dissociation. It may function as a negative regulator of axonal growth.
TMPH-01040	CBR1 Protein, Human, Recombinant (His) 20-beta-hydroxysteroid dehydrogenase,Carbonyl reductase [NAD...	Human	P. pastoris (Yeast)
	CBR1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.2 kDa and the accession number is P16152.
TMPH-01089	CBX7 Protein, Human, Recombinant (His) Chromobox protein homolog 7,CBX7	Human	E. coli
	CBX7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.3 kDa and the accession number is O95931.
TMPY-01595	PCBP1 Protein, Human, Recombinant (His) HNRPE1,hnRNP-E1,HEL-S-85,HNRPX,poly(rC) binding protein 1,hn...	Human	E. coli
	Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in pr...
TMPJ-01145	ABCB5 Protein, Human, Recombinant (Trx) ABCB5 P-gp,ATP-binding cassette sub-family B member...	Human	E. coli
	ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells. Furthermore, the ABCB5+ melanoma- initiating cells were demonstrated to express FL...
TMPY-01345	ACBD6 Protein, Human, Recombinant (His) acyl-CoA binding domain containing 6	Human	Baculovirus Insect Cells
	Human acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus. In mammals, there are six members of the acyl-CoA binding domain-containing (ACBD) family, and their annotation is not uniform. All six ACBD proteins contain an ACB domain at the N terminus, but they do not share significant homology at the C-terminal region. ACBD6 is a 32 kDa protein that is predicted by sequenc...
TMPH-01786	NCBP1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	NCBP1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 95.7 kDa and the accession number is Q09161.
TMPH-00389	OmcB Protein, Chlamydia trachomatis, Recombinant (His & SUMO)	Chlamydia trachomatis	E. coli
	In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. OmcB Protein, Chlamydia trachomatis, Recombinant (His & SUMO) is expressed in E...
TMPH-01884	PCBP2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	PCBP2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.0 kDa and the accession number is Q15366.
TMPH-01175	CBS Protein, Human, Recombinant (His) Serine sulfhydrase,Cystathionine beta-synthase,Beta-thionase...	Human	P. pastoris (Yeast)
	CBS Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-01090	CBX8 Protein, Human, Recombinant (His) Polycomb 3 homolog,hPc3,Pc3,Rectachrome 1,CBX8,Chro...	Human	E. coli
	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. CBX8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. Th...
TMPH-02160	SMARCB1 Protein, Human, Recombinant (His)	Human	E. coli
	SMARCB1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.0 kDa and the accession number is Q12824.
TMPH-01039	CBR1 Protein, Human, Recombinant (E. coli, His) Alcohol dehydrogenase [NAD(P)+] CBR1,CBR1,...	Human	E. coli
	CBR1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.2?kDa and the accession number is P16152.
TMPH-00732	RtcB Protein, E. coli, Recombinant (His)	E. coli	P. pastoris (Yeast)
	GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-phosphate (or cyclic-phosphate) and 5'-hydroxy ends that cannot be sealed by classical DNA ligases.
TMPH-00981	ABCB1 Protein, Human, Recombinant (His) Multidrug resistance protein 1,P-glycoprotein 1,ATP-binding ...	Human	E. coli
	ABCB1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPK-00246	MICB Protein, Human, Recombinant (His & Avi), Biotinylated MIC-B,MICB,PERB11.2	Human	HEK293 Cells
	MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. MICB Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His...
TMPH-02468	Mo-CBP3 Protein, Moringa oleifera, Recombinant (GST)	Moringa oleifera	E. coli
	Chitin-binding protein. Has antifungal activity against F.solani, F.oxysporum, C.musae and C.gloesporoides but not against P.oligandrum. Depending on concentration the antifungal activity can be fungistatic or fungicidal. Inhibits both spore germination and mycelial growth in F.solani at a concentration of 0.1 mg/ml. Has antifungal activity against C.krusei, C.albicans, C.tropicalis and C.parapsilosis. Has no chitinase, beta-glucanase or hemagglutinating activity. Acts as a flocculent. Mo-CBP3 P...
TMPY-03510	Cbl-c Protein, Human, Recombinant (His & GST) Cbl proto-oncogene C, E3 ubiquitin protein ligase,<...	Human	Baculovirus Insect Cells
	CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c g...
TMPH-01174	CBS Protein, Human, Recombinant (E. coli, His) Serine sulfhydrase,Beta-thionase,CBS,Cystathionine ...	Human	E. coli
	CBS Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-01930	CBFA2T1 Protein, Human, Recombinant (His & Myc) CDR,ETO,AML1T1,Eight twenty one protein,RUNX1T1,Cyclin-D-rel...	Human	E. coli
	CBFA2T1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01785	NCBP1 Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	NCBP1 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 99.3 kDa and the accession number is Q09161.
TMPH-01088	CBX5 Protein, Human, Recombinant (His & Myc) HP1 alpha,CBX5,Heterochromatin protein 1 homolog al...	Human	E. coli
	Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. CBX5 Protein...
TMPH-01598	CCBL2 Protein, Human, Recombinant (His & SUMO) KAT3,Kynurenine--oxoglutarate transaminase 3,CCBL2,...	Human	E. coli
	CCBL2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.4 kDa and the accession number is Q6YP21.
TMPH-00750	YcbX Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	YcbX Protein, E. coli, Recombinant (GST) is expressed in E. coli.
TMPJ-01344	TCblR Protein, Human, Recombinant (hFc) 8D6 antigen,CD320 antigen,Transcobalamin receptor,TCb	Human	HEK293 Cells
	TCblR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 58-60 KDa and the accession number is Q9NPF0.
TMPJ-01345	TCblR Protein, Human, Recombinant (His) FDC-signaling molecule 8D6,CD320,8D6 antigen,Transcobalamin ...	Human	HEK293 Cells
	TCblR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-58 KDa and the accession number is Q9NPF0.
TMPY-00885	MICB Protein, Human, Recombinant (His & hFc) MHC class I polypeptide-related sequence B,PERB11.2	Human	HEK293 Cells
	MICB Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 59.5 kDa and the accession number is A0A7D9H7X8.
TMPY-03504	CBFB Protein, Human, Recombinant (His) core-binding factor, β subunit,core-binding factor, beta sub...	Human	E. coli
	CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). CBFB is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enh...
TMPY-03963	CALCB Protein, Human, Recombinant (mFc) CGRP-II,calcitonin-related polypeptide β,calcitonin-related ...	Human	HEK293 Cells
	CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, blood, and cerebrospinal fluid. CGRP immunolabeling (IL) was detected in epidermal keratinocytes at levels that were especially high and widespread in the skin of humans from locations afflicted with postherpetic neuralgia (PHN) and complex region pain syndrome type 1 (CRPS), of ...

重组蛋白

CB2/CNR2 Protein, Human, Recombinant

Cat.No: TMPY-06623

Species: Human

Expression System: HEK293 Cells

Cathepsin B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02144

Species: Mouse

Expression System: HEK293 Cells

CNR1 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03256

Species: Rat

Expression System: E. coli

CNR1 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-01035

Species: Human

Expression System: HEK293 Cells

PPP1CB Protein, Human, Recombinant (His)

Cat.No: TMPH-02098

Species: Human

Expression System: E. coli

MICB Protein, Human, Recombinant (His)

Cat.No: TMPY-01066

Species: Human

Expression System: HEK293 Cells

MICB Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00245

Species: Human

Expression System: HEK293 Cells

CBR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03867

Species: Human

Expression System: E. coli

DCBLD2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03853

Species: Human

Expression System: HEK293 Cells

DCBLD1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03400

Species: Human

Expression System: HEK293 Cells

CBS Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02615

Species: Mouse

Expression System: E. coli

NCBP2 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01787

Species: Human

Expression System: E. coli

ACB1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03433

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

ACBD7 Protein, Human, Recombinant (His)

Cat.No: TMPY-03417

Species: Human

Expression System: E. coli

MICB Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00247

Species: Human

Expression System: HEK293 Cells

CKAP1/TBCB Protein, Human, Recombinant (His)

Cat.No: TMPY-03392

Species: Human

Expression System: E. coli

CBR1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01040

Species: Human

Expression System: P. pastoris (Yeast)

CBX7 Protein, Human, Recombinant (His)

Cat.No: TMPH-01089

Species: Human

Expression System: E. coli

PCBP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01595

Species: Human

Expression System: E. coli

ABCB5 Protein, Human, Recombinant (Trx)

Cat.No: TMPJ-01145

Species: Human

Expression System: E. coli

ACBD6 Protein, Human, Recombinant (His)

Cat.No: TMPY-01345

Species: Human

Expression System: Baculovirus Insect Cells

NCBP1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01786

Species: Human

Expression System: Baculovirus Insect Cells

OmcB Protein, Chlamydia trachomatis, Recombinant (His & SUMO)

Cat.No: TMPH-00389

Species: Chlamydia trachomatis

Expression System: E. coli

PCBP2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01884

Species: Human

Expression System: E. coli

CBS Protein, Human, Recombinant (His)

Cat.No: TMPH-01175

Species: Human

Expression System: P. pastoris (Yeast)

CBX8 Protein, Human, Recombinant (His)

Cat.No: TMPH-01090

Species: Human

Expression System: E. coli

SMARCB1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02160

Species: Human

Expression System: E. coli

CBR1 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01039

Species: Human

Expression System: E. coli

RtcB Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00732

Species: E. coli

Expression System: P. pastoris (Yeast)

ABCB1 Protein, Human, Recombinant (His)

Cat.No: TMPH-00981

Species: Human

Expression System: E. coli

MICB Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00246

Species: Human

Expression System: HEK293 Cells

Mo-CBP3 Protein, Moringa oleifera, Recombinant (GST)

Cat.No: TMPH-02468

Species: Moringa oleifera

Expression System: E. coli

Cbl-c Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03510

Species: Human

Expression System: Baculovirus Insect Cells

CBS Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01174

Species: Human

Expression System: E. coli

CBFA2T1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01930

Species: Human

Expression System: E. coli

NCBP1 Protein, Human, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-01785

Species: Human

Expression System: E. coli

CBX5 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01088

Species: Human

Expression System: E. coli

CCBL2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01598

Species: Human

Expression System: E. coli

YcbX Protein, E. coli, Recombinant (GST)

Cat.No: TMPH-00750

Species: E. coli

Expression System: E. coli

TCblR Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01344

Species: Human

Expression System: HEK293 Cells

TCblR Protein, Human, Recombinant (His)

Cat.No: TMPJ-01345

Species: Human

Expression System: HEK293 Cells

MICB Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-00885

Species: Human

Expression System: HEK293 Cells

CBFB Protein, Human, Recombinant (His)

Cat.No: TMPY-03504

Species: Human

Expression System: E. coli

CALCB Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03963

Species: Human

Expression System: HEK293 Cells

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