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121

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T12670	(Rac)-MGV354 MGV354,外消旋MGV354	Others	Others
	(Rac)-MGV354 (MGV354) 是 MGV354 的外消旋体，MGV354 是可溶性鸟苷酸环化酶活化剂，在 GTM-3E 和 CHO 细胞中 EC50分别为 5 nM 和小于 0.5 nM。
T7824	Eberconazole Nitrate 硝酸依柏康唑,Ebernet	Antifungal	Microbiology/Virology
	Eberconazole Nitrate (Ebernet) 是一种二氯咪唑衍生物，具有抗真菌活性，效果比Ketoconazole、Clotrimazole 和Miconazole 强。它通过局部给药对皮肤癣菌病具有潜在的研究价值。
T0222	Proparacaine hydrochloride 盐酸丙美卡因,Proparacaine HCl,Proxymetacaine Hydrochloride	Apoptosis; Sodium Channel	Apoptosis; Membrane transporter/Ion channel
	Proparacaine hydrochloride (Proparacaine HCl) 是 Lidocaine 的衍生物，具有糖皮质激素样活性和免疫调节作用。
T1163	Betamethasone valerate Betnovate,倍他米松戊酸酯,Betaderm,Betamethasone 17-valerate,Luxiq	Glucocorticoid Receptor	Endocrinology/Hormones
	Betamethasone valerate (Luxiq) 的 17 戊酸酯，是一种具有抗炎活性的局部皮质类固醇。它能够抑制放射标记的糖皮质激素地塞米松与人表皮(IC50:5 nM)及小鼠皮肤(IC50:6 nM)的结合。它可用于研究复发性口疮。
T0513	Diiodohydroxyquinoline Iodoquinol,双碘喹,5,7-Diiodo-8-hydroxyquinoline,5,7-Diiodo-8-quinolinol	Antibacterial; Antibiotic	Microbiology/Virology
	Diiodohydroxyquinoline (Iodoquinol) 有较好的抗菌作用。
T13184	Topilutamide Fluridil,BP766	Others	Others
	Topilutamide (Fluridil) 是局部的非甾体类抗雄激素。
T25956	Piketoprofen Calmatel	Others	Others
	Piketoprofen (Calmatel) 是一种局部非甾体抗炎药。
T9045	Bemotrizinol	Others	Others
	Bemotrizinol 是紫外线 (UV) 滤光片，已被证实可用它接受N-氧化物光氧化产生的原子氧。
T34485	Safotibant LF220542,LF 220542,LF 22-0542,LF-220542,LF-22-0542,LF22-0542	Bradykinin Receptor	GPCR/G Protein
	Safotibant (LF-22-0542) 是一种缓激肽 B1 受体拮抗剂，具有抗炎和镇痛活性，可用于局部治疗糖尿病性黄斑水肿。
T3357	Clascoterone Cortexolone 17 alpha-propionate,17 alpha-propionate,21-羟基-17-(1-氧代丙氧基)孕甾-4-烯-3,20-二酮,CB-03-01,Cortexolone 17α-propionate	Androgen Receptor	Endocrinology/Hormones
	Clascoterone (CB-03-01) 是一种新型的局部和外周的雄性激素拮抗剂。
T0409	Phthalylsulfacetamide 酞磺醋胺,Enterosulfon,Enterosulfamid,Tamid	Antibacterial	Microbiology/Virology
	Phthalylsulfacetamide (Tamid) 是一种磺胺类抗生素，用于皮肤和结膜的局部应用。
T27244	Efletirizine UCB 28754,UCB-28754,UCB28754	Lipoxygenase; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Efletirizine (UCB-28754) 是一种组胺受体拮抗剂，对5-脂氧合酶(5-LO)具有抑制作用，对可用于局部治疗过敏疾病。
T0460	Pramocaine hydrochloride Pramoxine hydrochloride,盐酸普莫卡因,Pramoxine HCl	Sodium Channel	Membrane transporter/Ion channel
	Pramocaine hydrochloride (Pramoxine HCl) 可以降低神经细胞膜对钠离子的通透性，阻断神经冲动的产生和传导。
T0107	Halcinonide Halcimat,Halciderm,哈西奈德,Halcinonida,氯氟舒松,SQ-18566	Glucocorticoid Receptor; Smo	Endocrinology/Hormones; Stem Cells
	Halcinonide (Halciderm) 是一种糖皮质激素，可用于局部皮肤感染的研究。
T16531	Picaridin 埃卡瑞丁,Lcaridin	Parasite	Microbiology/Virology
	Picaridin (Lcaridin) 是一种广谱节肢动物驱避剂，作用于蚊子和蜱的嗅觉感应，与其气味受体蛋白相互作用。
T21193	Isoflupredone Acetate	Others	Others
	Isoflupredone Acetate 是一种具有局部抗炎活性的皮质类固醇。
T4572	Desoximetasone 去羟米松,Desoximetasonum,Topicort,Desoxymethasone,Desoximetasona	Others	Others
	Desoximetasone (Desoximetasona) 是一种可缓解皮疹等多种皮肤疾病的皮质类固醇。
T1147	Chlorhexidine dihydrochloride 盐酸氯己定,Chlorhexidine hydrochloride,Chlorhexidine 2HCl,NSC-185	CAT; Cell wall; Antibacterial; Antibiotic; Antifection	Immunology/Inflammation; Microbiology/Virology; oxidation-reduction
	Chlorhexidine dihydrochloride (NSC-185) 是一种消毒剂和局部抗感染剂，也用作漱口水以防止口腔菌斑。
T2333	Efinaconazole KP-103,艾氟康唑	Antifungal	Microbiology/Virology
	Efinaconazole (KP-103) 是一种三唑类抗真菌剂，抑制T. mentagrophytesSM-110和C. albicansATCC 10231菌株的MIC 值分别为 0.0039 μg/mL 和 0.00098 μg/mL
T1253	Chlorindanol 7-Chloro-4-indanol,Lanesta,Clorindanol,4-氯-7-羟基氢化茚,7-氯-4-羟基氢化茚	Others	Others
	Chlorindanol (Lanesta) 是新型的防腐剂。
T6665	Sertaconazole nitrate FI-7045,Ginedermofix,FI7056,Ertaczo,硝酸舍他康唑	Antibiotic; Antifungal	Microbiology/Virology
	Sertaconazole nitrate (FI-7045) 是一种局部广谱抗真菌药，可用于治疗浅表皮肤和粘膜感染。
T7363	Ibuprofen Piconol U75630,匹美诺芬,布洛芬吡啶甲醇	Others	Others
	Ibuprofen Piconol (U75630) 是非甾体抗炎药物，局部使用可缓解原发性热灼伤和晒伤。
T9065	4-Isopropylcatechol	Others	Others
	4-Isopropylcatechol 是一种有效的脱色剂，可用于特定黑色素沉着症患者的局部治疗。
T22408	Proflavine 吡啶-3,6-二胺,3,6-Diaminoacridine	Antibacterial	Microbiology/Virology
	Proflavine (3,6-Diaminoacridine) 是吖啶染料，可用作抗菌剂。它是 DNA 嵌入剂，能够阻滞Kir3.2孔。它用作与 Kir3.2 相关的神经系统疾病的研究。
T20655	Polyquaternium-1 聚季铵盐-1,PQ-1,Polidronium chloride	Antibacterial	Microbiology/Virology
	Polyquaternium-1 (PQ-1) 具有很强的抑菌作用，对眼睛的刺激很小，可用作聚阳离子眼科防腐剂。 Polyquaternium-1 抑制多剂量外用药物瓶中微生物污染物的生长。
T6696	Tazarotene 他扎罗汀,Tazorac,AGN 190168,Zorac	Retinoid Receptor; Autophagy	Autophagy; Metabolism
	Tazarotene (Zorac) 是一种选择性视黄酸受体激动剂，用于研究寻常痤疮和斑块状银屑病。
T10295	Amantanium bromide 金刚溴铵,Amantanil bromidum	Others	Others
	Amantanium bromide (Amantanil bromidum) 是一种季铵抗菌/抗真菌剂，可用作手术防腐剂以及粘液和皮肤感染的局部治疗。
T0897	Nitrofurazone NFZ,呋喃西林,Nitrofural,Furacilin	Dehydrogenase; Antibacterial; Glutathione reductase; Antibiotic	Metabolism; Microbiology/Virology; oxidation-reduction
	Nitrofurazone (Furacilin) 是一种抗生素。
T0979	Dequalinium chloride Dequafungan,地喹氯铵,Danical,Decabis	Potassium Channel; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel
	Dequalinium chloride (Decabis) 是一种apamin 敏感型的钾离子通道选择性阻断剂。
T4644	Tapinarof GSK2894512,Benvitimod,苯烯莫德,WBI 1001	AhR; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism
	Tapinarof (Benvitimod) 是一种从发光杆菌中提取的天然产物，可消除炎症。它是芳烃受体 (AhR) 激动剂，EC50为 13 nM。
T1142	Clindamycin phosphate Clindamycin 2-phosphate,Clindamycin 2-dihydrogen phosphate,NSC 618653,U-28508,克林霉素磷酸酯	ribosome; Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Clindamycin phosphate (Clindamycin 2-dihydrogen phosphate) 是一种抗生素，抑制微生物的核糖体作用。可研究厌氧菌感染和原虫疾病。
T14981	Clobetasone butyrate	Glucocorticoid Receptor	Endocrinology/Hormones
	Clobetasone butyrate 是糖皮质类固醇，特别是在皮肤上，具有局部抗炎活性。它可用于改善皮质类固醇反应性症状，如特应性皮炎、牛皮癣。
T0044	Oxethazaine 奥昔卡因,Oxetacaine	HBV; Sodium Channel	Membrane transporter/Ion channel; Microbiology/Virology
	Oxethazaine (Oxetacaine) 是一种具有耐酸性和口服活性试剂，是芬特明的酸性前体，有潜力缓解消化性溃疡疾病或食管炎引起的疼痛。
T1000L	Chlorhexidine diacetate 醋酸氯己定,Hibitane diacetate,Chlorhexidine Acetate,Bactigras	CAT; Antibacterial; Antibiotic; Antifection	Microbiology/Virology; oxidation-reduction
	Chlorhexidine diacetate (Bactigras) 是一种双胍类杀菌剂，能快速消灭革兰氏阳性菌和革兰氏阴性菌。它也用作漱口水以防止口腔菌斑。
T32114	Hydrocortisone aceponate Suniderma,Efficort,Hydrocortisone 17-propionate 21-acetate	Glucocorticoid Receptor	Endocrinology/Hormones
	Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) 是一种有效的外用糖皮质激素，以乳膏的形式用于治疗各种皮肤病。
T21444	Diphenylcyclopropenone DPCP,Diphencyprone,二苯基环丙烯酮	Others	Others
	Diphenylcyclopropenone (DPCP) 是局部免疫调节剂，可用于研究斑秃。
T13187	Topterone Win 17665	Androgen Receptor	Endocrinology/Hormones
	Topterone（Win 17,665）是一种有效的局部抗雄激素，抑制睾酮和二氢睾酮对阉割未成熟雄性仓鼠腰部器官发育的刺激。
T8122	Mafenide Acetate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Mafenide Acetate 是一种磺酰胺类抗菌剂，可用于烧伤创面。它通过抑制核苷酸合成，对革兰氏阳性和革兰氏阴性生物有活性。
T28974	Ticolubant	Calcium Channel; LTR	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism
	Ticolubant 是一种具有口服活性的白三烯 B4 拮抗剂，对人类中性粒细胞 LTB4 受体具有很高的亲和力（Ki = 0.78 nM），能阻断 LTB4 诱导的 Ca2+ 迁移，IC50 为 6.6±1.5 nM，并在小鼠皮肤炎症模型中显示出局部抗炎活性。
T0921	Sulfabenzamide Sultrin,N-Sulfanilylbenzamide,苯甲酰磺胺	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Sulfabenzamide (N-Sulfanilylbenzamide) 是一种磺胺类抗菌剂，可单独使用或与磺胺噻唑和磺胺乙酰胺一起用作阴道内的局部抗菌制剂。
T0830	Bithionol 硫双二氯酚,Actamer,硫氯酚	cAMP; Parasite	GPCR/G Protein; Microbiology/Virology
	Bithionol (Actamer) 是一种抗寄生虫药物，对若干癌细胞有抑制作用。
T0888	Felbinac Dapson,4-联苯乙酸,4-Biphenylacetic acid	COX	Immunology/Inflammation; Neuroscience
	Felbinac (Dapson) 是非甾体抗炎药，可用于肌肉炎症和关节炎的研究。
T0376	Crotamiton Eurax,Crotamitone,克罗米通,Veteusan	Parasite	Microbiology/Virology
	Crotamiton (Eurax) 既是杀疥螨剂，可研究疥疮，也是止痒剂, 可除去疥疮寄生虫。
T0289	9-Aminoacridine Aminacrine,9-氨基吖啶	Others; HIV Protease; Antibacterial	Microbiology/Virology; Others; Proteases/Proteasome
	9-Aminoacridine 是一种具有龋齿传播特性的抗菌剂，可用作局部消毒剂。它也是一种高度荧光染料，实验用作一种诱变剂，是细胞内 pH 的指示剂。
T3279	Silver sulfadiazine Silvadene,磺胺嘧啶银,Dermazin,Flamazine	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Silver sulfadiazine (Dermazin) 是一种磺胺类抗生素，具有抗菌和抗真菌活性。它的通磺胺部分(SD-SDZ) 对细菌生长有双重抑制作用，可阻止细菌叶酸吸收以及 DNA 合成。它释放的银结合并破坏 DNA 结构，阻止细菌 DNA 复制。
T1026	Mafenide hydrochloride 4-Aminomethylbenzenesulfonamide hydrochloride,盐酸磺胺米隆	Antibacterial; Antibiotic; Carbonic Anhydrase	Metabolism; Microbiology/Virology
	Mafenide hydrochloride (4-Aminomethylbenzenesulfonamide hydrochloride) 是一种有效的磺酰胺类抗菌剂，可用于烧伤创面。它通过抑制核苷酸合成，对革兰氏阳性和革兰氏阴性生物均具有活性。
T7423	Diquafosol tetrasodium 地夸磷索四钠,INS365	P2Y Receptor	GPCR/G Protein; Neuroscience
	Diquafosol tetrasodium (INS365) 是一种 P2Y2 受体激动剂，可刺激眼组织粘蛋白的分泌。它可改善泪膜稳定性和视觉功能，作为干眼症的局部治疗。
T1531	Mometasone furoate 糠酸莫美他松,糠酸莫米松,Sch32088	Glucocorticoid Receptor	Endocrinology/Hormones
	Mometasone furoate (Sch32088) 是糖皮质激素受体激动剂，具有抗炎和抗过敏作用。它是皮质固醇类试剂，动物模型中，可局部应用于气道炎症、慢性皮肤湿疹、哮喘。
T38625	Tanimilast CHF-6001	PDE	Metabolism
	Tanimilast (CHF-6001) 是一种新型的高效选择性磷酸二酯酶 4 抑制剂，IC 50值为0.026 ± 0.006 nM。Tanimilast 具有强大的抗炎活性，适用于肺部局部用药。Tanimilast 用于研究阻塞性肺病。
T15719	Latanoprostene bunod LBN,NCX116	Others	Others
	Latanoprostene bunod (LBN) 是一氧化氮 (NO) 供体前列腺素 F2a 类似物，有用于开角型青光眼或高眼压 (OHT) 患者降低眼压 (IOP) 的局部眼科的研究潜力。

化合物

Cat.No: T12670

Synonym: MGV354,外消旋MGV354

Target: Others

Eberconazole Nitrate

Cat.No: T7824

Synonym: 硝酸依柏康唑,Ebernet

Target: Antifungal

Proparacaine hydrochloride

Cat.No: T0222

Synonym: 盐酸丙美卡因,Proparacaine HCl,Proxymetacaine Hydrochloride

Target: Apoptosis, Sodium Channel

Betamethasone valerate

Cat.No: T1163

Synonym: Betnovate,倍他米松戊酸酯,Betaderm,Betamethasone 17-valerate,Luxiq

Target: Glucocorticoid Receptor

Diiodohydroxyquinoline

Cat.No: T0513

Synonym: Iodoquinol,双碘喹,5,7-Diiodo-8-hydroxyquinoline,5,7-Diiodo-8-quinolinol

Target: Antibacterial, Antibiotic

Cat.No: T13184

Synonym: Fluridil,BP766

Target: Others

Cat.No: T25956

Synonym: Calmatel

Target: Others

Cat.No: T9045

Target: Others

Cat.No: T34485

Synonym: LF220542,LF 220542,LF 22-0542,LF-220542,LF-22-0542,LF22-0542

Target: Bradykinin Receptor

Cat.No: T3357

Synonym: Cortexolone 17 alpha-propionate,17 alpha-propionate,21-羟基-17-(1-氧代丙氧基)孕甾-4-烯-3,20-二酮,CB-03-01,Cortexolone 17α-propionate

Target: Androgen Receptor

Phthalylsulfacetamide

Cat.No: T0409

Synonym: 酞磺醋胺,Enterosulfon,Enterosulfamid,Tamid

Target: Antibacterial

Cat.No: T27244

Synonym: UCB 28754,UCB-28754,UCB28754

Target: Lipoxygenase, Histamine Receptor

Pramocaine hydrochloride

Cat.No: T0460

Synonym: Pramoxine hydrochloride,盐酸普莫卡因,Pramoxine HCl

Target: Sodium Channel

Cat.No: T0107

Synonym: Halcimat,Halciderm,哈西奈德,Halcinonida,氯氟舒松,SQ-18566

Target: Glucocorticoid Receptor, Smo

Cat.No: T16531

Synonym: 埃卡瑞丁,Lcaridin

Target: Parasite

Isoflupredone Acetate

Cat.No: T21193

Target: Others

Cat.No: T4572

Synonym: 去羟米松,Desoximetasonum,Topicort,Desoxymethasone,Desoximetasona

Target: Others

Chlorhexidine dihydrochloride

Cat.No: T1147

Synonym: 盐酸氯己定,Chlorhexidine hydrochloride,Chlorhexidine 2HCl,NSC-185

Target: CAT, Cell wall, Antibacterial, Antibiotic, Antifection

Cat.No: T2333

Synonym: KP-103,艾氟康唑

Target: Antifungal

Cat.No: T1253

Synonym: 7-Chloro-4-indanol,Lanesta,Clorindanol,4-氯-7-羟基氢化茚,7-氯-4-羟基氢化茚

Target: Others

Sertaconazole nitrate

Cat.No: T6665

Synonym: FI-7045,Ginedermofix,FI7056,Ertaczo,硝酸舍他康唑

Target: Antibiotic, Antifungal

Ibuprofen Piconol

Cat.No: T7363

Synonym: U75630,匹美诺芬,布洛芬吡啶甲醇

Target: Others

4-Isopropylcatechol

Cat.No: T9065

Target: Others

Cat.No: T22408

Synonym: 吡啶-3,6-二胺,3,6-Diaminoacridine

Target: Antibacterial

Polyquaternium-1

Cat.No: T20655

Synonym: 聚季铵盐-1,PQ-1,Polidronium chloride

Target: Antibacterial

Cat.No: T6696

Synonym: 他扎罗汀,Tazorac,AGN 190168,Zorac

Target: Retinoid Receptor, Autophagy

Amantanium bromide

Cat.No: T10295

Synonym: 金刚溴铵,Amantanil bromidum

Target: Others

Cat.No: T0897

Synonym: NFZ,呋喃西林,Nitrofural,Furacilin

Target: Dehydrogenase, Antibacterial, Glutathione reductase, Antibiotic

Dequalinium chloride

Cat.No: T0979

Synonym: Dequafungan,地喹氯铵,Danical,Decabis

Target: Potassium Channel, PKC

Cat.No: T4644

Synonym: GSK2894512,Benvitimod,苯烯莫德,WBI 1001

Target: AhR, Aryl Hydrocarbon Receptor

Clindamycin phosphate

Cat.No: T1142

Synonym: Clindamycin 2-phosphate,Clindamycin 2-dihydrogen phosphate,NSC 618653,U-28508,克林霉素磷酸酯

Target: ribosome, Antibacterial, Antibiotic, Parasite

Clobetasone butyrate

Cat.No: T14981

Target: Glucocorticoid Receptor

Cat.No: T0044

Synonym: 奥昔卡因,Oxetacaine

Target: HBV, Sodium Channel

Chlorhexidine diacetate

Cat.No: T1000L

Synonym: 醋酸氯己定,Hibitane diacetate,Chlorhexidine Acetate,Bactigras

Target: CAT, Antibacterial, Antibiotic, Antifection

Hydrocortisone aceponate

Cat.No: T32114

Synonym: Suniderma,Efficort,Hydrocortisone 17-propionate 21-acetate

Target: Glucocorticoid Receptor

Diphenylcyclopropenone

Cat.No: T21444

Synonym: DPCP,Diphencyprone,二苯基环丙烯酮

Target: Others

Cat.No: T13187

Synonym: Win 17665

Target: Androgen Receptor

Mafenide Acetate

Cat.No: T8122

Target: Others, Antibacterial, Antibiotic

Cat.No: T28974

Target: Calcium Channel, LTR

Cat.No: T0921

Synonym: Sultrin,N-Sulfanilylbenzamide,苯甲酰磺胺

Target: Antibacterial, Antibiotic, Autophagy

Cat.No: T0830

Synonym: 硫双二氯酚,Actamer,硫氯酚

Target: cAMP, Parasite

Cat.No: T0888

Synonym: Dapson,4-联苯乙酸,4-Biphenylacetic acid

Target: COX

Cat.No: T0376

Synonym: Eurax,Crotamitone,克罗米通,Veteusan

Target: Parasite

9-Aminoacridine

Cat.No: T0289

Synonym: Aminacrine,9-氨基吖啶

Target: Others, HIV Protease, Antibacterial

Silver sulfadiazine

Cat.No: T3279

Synonym: Silvadene,磺胺嘧啶银,Dermazin,Flamazine

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Mafenide hydrochloride

Cat.No: T1026

Synonym: 4-Aminomethylbenzenesulfonamide hydrochloride,盐酸磺胺米隆

Target: Antibacterial, Antibiotic, Carbonic Anhydrase

Diquafosol tetrasodium

Cat.No: T7423

Synonym: 地夸磷索四钠,INS365

Target: P2Y Receptor

Mometasone furoate

Cat.No: T1531

Synonym: 糠酸莫美他松,糠酸莫米松,Sch32088

Target: Glucocorticoid Receptor

Cat.No: T38625

Synonym: CHF-6001

Target: PDE

Latanoprostene bunod

Cat.No: T15719

Synonym: LBN,NCX116

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5781	taraxasteryl acetate 蒲公英甾醇醋酸酯,醋酸蒲公英酯	Antibacterial	Microbiology/Virology
	Taraxasteryl acetate 是分离自矢状疟原虫中，具有广谱的抗炎活性。它能够改善右旋糖酐、酵母聚糖及花生四烯酸诱导的大鼠后爪水肿。它可用于研究局部炎症。
T4850	PCL 016 2-吡啶甲酸,2-Picolinic acid	Virus Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology
	PCL 016 (2-Picolinic acid) 是一种局部抗病毒剂，可抑制兔体内的腺病毒复制。
T0444	Econazole (±)-Econazol,益康唑	Antibiotic; Antifection; Antifungal	Microbiology/Virology
	Econazole ((±)-Econazol) 是一种咪唑衍生物，是一种抗真菌剂。
T1289	Fusidic acid sodium salt Sodium fusidate,夫西地酸钠,Fusidate Sodium,Fucidin,SQ-16360	Others; CAT; Antibacterial; Antibiotic	Microbiology/Virology; Others; oxidation-reduction
	Fusidic acid sodium salt (SQ-16360) 是一种Fusidium coccineum 属甾体类抑菌抗生素。它阻止核糖体释放翻译延长因子G 来抑制细菌生长。
T2916	Patchouli alcohol 百秋李醇,Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol,广藿香醇	Antibacterial; Antifungal	Microbiology/Virology
	Patchouli alcohol (Patchoulol) 是一种从广藿香中提取的天然三环倍半萜，有抗幽门螺杆菌和抗炎活性。
T5562	Methyl nicotinate 烟酸甲酯,methyl pyridine-3-carboxylate	Others	Others
	Methyl nicotinate (methyl pyridine-3-carboxylate) 是一种盐酸甲酯，发现于酒精饮料中，在非处方局部制剂中用作活性成分，用于研究肌肉和关节疼痛。
TN1006	Tirucallol	NOS; NO Synthase; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Tirucallol 是一种四环三萜，分离自Euphorbia lacteal 乳胶。它能够抑制小鼠模型中的耳部水肿，并阻碍脂多糖刺激的巨噬细胞中亚硝酸盐的产生，具有局部消炎作用。
T1678	Nystatin Stamycin,Fungicidin,制霉菌素,Nystavescent	Apoptosis; Antibiotic; Antifungal	Apoptosis; Microbiology/Virology
	Nystatin (Fungicidin) 是一种口服对酵母和支原体有效的多烯类抗真菌抗生素。它能增加质膜对包括氯离子等小单价离子的通透性。它可部分阻止 Oxaliplatin 诱导的脂筏聚集、DR4 和 DR5 聚集的胆固醇隔离试剂，减少细胞凋亡。
T1157	Moxidectin milbemycin B,CL301423,莫昔克丁,莫西菌素	GluCls; Antibiotic; Parasite	Microbiology/Virology
	Moxidectin (CL301423) 是可用于预防和控制心丝虫和蛔虫的一种驱虫剂。
T1168	Desonide Tridesilon,地索奈德,Locapred,Prednacinolone	Glucocorticoid Receptor	Endocrinology/Hormones
	Desonide (Prednacinolone) 是一种非氟化皮质类固醇抗炎剂，能够作用于糖皮质激素受体。
T25998	Pseudomonic acid D Pseudomonic D
	Pseudomonic acid D is a topical antibiotic agent used against superficial skin infections such as impetigo or folliculitis.
TN4742	Patulitrin	Antifection	Microbiology/Virology
	Patulitrin has antioxidant, anti-inflammatory, and larvicidal activities, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice.
T6913	Nystatin A3 制霉菌素 A3,制霉菌素,Fungicidin,Nystatin	Others	Others
	Nystatin A3 (Fungicidin) 是从Streptomyces noursei 中产生的一种多烯类抗真菌药，用作治疗口咽念珠菌病的外用剂。
TN5221	(-)-Variabilin
	Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3.Variabilin is also an antimicrobial furanosesterterpene. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro a...
TN3573	Camaric acid	Antifection	Microbiology/Virology
	Camaric acid shows antibacterial activity against Staphylococcus aureus and methicillin resistant S. aureus with IC50 values 8.74 and 8.09 uM, respectively, it also shows moderate antileishmanial activity and highly potent antitrypanosomal activity. Camar

天然产物

taraxasteryl acetate

Cat.No: T5781

Synonym: 蒲公英甾醇醋酸酯,醋酸蒲公英酯

Target: Antibacterial

Cat.No: T4850

Synonym: 2-吡啶甲酸,2-Picolinic acid

Target: Virus Protease, Endogenous Metabolite

Cat.No: T0444

Synonym: (±)-Econazol,益康唑

Target: Antibiotic, Antifection, Antifungal

Fusidic acid sodium salt

Cat.No: T1289

Synonym: Sodium fusidate,夫西地酸钠,Fusidate Sodium,Fucidin,SQ-16360

Target: Others, CAT, Antibacterial, Antibiotic

Patchouli alcohol

Cat.No: T2916

Synonym: 百秋李醇,Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol,广藿香醇

Target: Antibacterial, Antifungal

Methyl nicotinate

Cat.No: T5562

Synonym: 烟酸甲酯,methyl pyridine-3-carboxylate

Target: Others

Cat.No: TN1006

Target: NOS, NO Synthase, Prostaglandin Receptor

Cat.No: T1678

Synonym: Stamycin,Fungicidin,制霉菌素,Nystavescent

Target: Apoptosis, Antibiotic, Antifungal

Cat.No: T1157

Synonym: milbemycin B,CL301423,莫昔克丁,莫西菌素

Target: GluCls, Antibiotic, Parasite

Cat.No: T1168

Synonym: Tridesilon,地索奈德,Locapred,Prednacinolone

Target: Glucocorticoid Receptor

Pseudomonic acid D

Cat.No: T25998

Synonym: Pseudomonic D

Cat.No: TN4742

Target: Antifection

Cat.No: T6913

Synonym: 制霉菌素 A3,制霉菌素,Fungicidin,Nystatin

Target: Others

Cat.No: TN5221

Cat.No: TN3573

Target: Antifection

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