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Search Results for " gram-positive bacteria "

247

抑制剂 & 化合物

85

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Cat. No.	Product Name	Target	Signaling Pathways
T14391	Azidamfenicol	Antibacterial; Antibiotic	Microbiology/Virology
	Azidamfenicol 抑制核糖体肽基转移酶，Ki 为 22 µM。Azidamfenicol 是一种广谱氯霉素类抗生素。
T4998L	Cefpodoxime (free acid)	Others	Others
	Cefpodoxime (free acid) 是一种口服的第三代头孢菌素抗生素。除铜绿假单胞菌、肠球菌和脆弱拟杆菌外，它对大多数革兰氏阳性和革兰氏阴性微生物均有效。
T9680	Irloxacin	Antibacterial	Microbiology/Virology
	Irloxacin 是一种口服活性的喹诺酮类抗菌剂，在酸性条件下具有更强大的活性。在体外，Irloxacin 对革兰氏阳性菌和革兰氏阴性菌都具有良好的抗菌谱。
T20525	Chloramphenicol palmitate	Antibacterial; Antibiotic	Microbiology/Virology
	Chloramphenicol palmitate 是一种广谱抗生素，对革兰氏阳性和革兰氏阴性细菌具有活性。 Chloramphenicol palmitate 可用于在含有氯霉素抗性基因的转化细胞中作为细菌选择剂的研究。
T1008	Cephalexin 头孢氨苄,Cefalexin,Cephacillin	Antibacterial; Antibiotic	Microbiology/Virology
	Cephalexin (Cephacillin) 是一种强口服活性的头孢菌素抗生素。它通过破坏细菌细胞壁的生长来杀死革兰氏阳性和一些革兰氏阴性细菌。它可研究肺炎、链球菌性咽喉炎、细菌性心内膜炎等。
T6582	Mezlocillin Sodium 美洛西林钠,Baycipen	Antibacterial; Antibiotic	Microbiology/Virology
	Mezlocillin Sodium (Baycipen) 是一种青霉素 β-内酰胺类抗生素，用于治疗由易感染微生物引起的细菌感染。
T5006	Flucloxacillin sodium 氟氯西林钠,floxacillin sodium	Antibacterial; Antibiotic	Microbiology/Virology
	Flucloxacillin sodium (floxacillin sodium) 是一种高活性抗生素，抑制革兰氏阳性和革兰氏阴性菌。
T3117	Marbofloxacin 马波沙星,Marbofloxacine,Zeniquin,Marbocyl	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Marbofloxacin (Zeniquin) 是一种具有口服活性的氟喹诺酮类广谱抗菌剂。它可研究革兰氏阳性和革兰氏阴性细菌以及支原体引起的感染。
T0396	Pipemidic acid 吡哌酸,Acido pipemidico	Antibacterial; Antibiotic	Microbiology/Virology
	Pipemidic acid (Acido pipemidico) 是一种新型抗菌剂，对革兰氏阴性菌和某些革兰氏阳性细菌具有活性，可研究肠道、泌尿和胆道感染。
T0116	Balofloxacin	DNA gyrase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素，可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成，对革兰氏阴性，革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道，肠道和泌尿道感染。
TP1444	Magainin 2 蛙皮素 2	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Magainin 2是从非洲爪蟾皮肤中分离得到的一种抗菌肽。它对许多革兰氏阴性和革兰氏阳性细菌显示出抗生素活性，对原生动物也有活性。它通过优先与细菌膜中丰富的阴离子磷脂相互作用而发挥细胞毒性作用。
T9066	Merafloxacin CI 934	SARS-CoV	Microbiology/Virology
	Merafloxacin (CI 934) 是一种氟喹诺酮类抗菌药物，也被确定为 SARS-CoV-2 的 1 PRF 抑制剂。它对革兰氏阳性菌和革兰氏阴性菌具有体外活性。
T7865	Danofloxacin 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine	Others; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Danofloxacin (Danofloxacin free base) free base 是一种具有口服活性第三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶发挥抗菌作用。它可用于牛，猪和鸡呼吸道疾病的研究。
T2692	A40926 Dalbavancin Impurity,达巴霉素杂质	Antibacterial	Microbiology/Virology
	A40926 (Dalbavancin Impurity) 是Dalbavancin 的前体，是一种糖肽抗生素。它抑制革兰氏阳性细菌，对淋病奈瑟氏球菌非常有效。
T0133	Cefdinir FK-482,头孢地尼,CI-983,PD 134393	Glutathione Peroxidase; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology
	Cefdinir (FK-482) 是头孢菌素类中的一种半合成广谱抗生素，对几种革兰氏阴性和革兰氏阳性细菌引起的感染有效。它可研究耳，鼻窦，喉咙和皮肤的常见细菌感染。
T73997	Anti gram-positive/negative bacteria agent 1
	Anti gram-positive/negative bacteria agent 1 是一种含有基于MECAM的人工铁载体的抗生素化合物。
T20774	Sarafloxacin A-56620,A 56620,A56620,沙拉沙星	Antibacterial; Antibiotic	Microbiology/Virology
	Sarafloxacin (A56620) 对革兰氏阳性菌和革兰氏阴性菌具有抗菌活性。
T1640	Ciprofloxacin Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ciprofloxacin (Bay-09867) 是一种有高抗菌活性的氟喹诺酮类抗生素。
T11315	Fosmidomycin sodium salt FR-31564 sodium salt	Antibiotic; Parasite	Microbiology/Virology
	Fosmidomycin sodium salt (FR-31564 sodium salt) 是一种抗感染类抗生素，具有抗疟疾活性，抑制革兰氏阴性菌和革兰氏阳性菌。
T11301L	Flomoxef sodium	Others	Others
	Flomoxef sodium 属于奥沙环类抗生素，对多种革兰氏阳性菌均具有良好的杀灭活性。
T0425	Pefloxacin Mesylate Pefloxacinium mesylate,甲磺酸培氟沙星	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Pefloxacin Mesylate (Pefloxacinium mesylate) 是一种抗菌化合物，可抑制DNA 旋转酶阻断DNA 复制。
T11123	DuP 105	Antibacterial; Antibiotic	Microbiology/Virology
	DuP 105是可口服的oxazolidinone类化合物，这是一种新型合成的抗菌化合物，对革兰氏阳性细菌具有有效性。
T6706	Ticarcillin sodium Ticarpen hydrate,Aerugipen hydrate,替卡西林单钠盐单水合物,BRL 2288,AB 2288,Monapen	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Ticarcillin sodium (Aerugipen hydrate) 主要用于抗革兰氏阴性菌, 也能用于研究嗜麦芽感染。
TP1763L	Magainin 1 acetate	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Magainin 1 acetate 是一种抗菌肽。它对许多革兰氏阴性和革兰氏阳性细菌表现出抗生素活性。
T4020	Cadazolid ACT-179811,卡达唑利德	Antibacterial; Antibiotic	Microbiology/Virology
	Cadazolid (ACT-179811) 是一种新型恶唑烷酮类抗生素，对Clostridium difficile 有活性。
T73054	Moiramide B	Acetyl-CoA Carboxylase; Antibiotic	Metabolism; Microbiology/Virology
	Moiramide B 是一种高效的乙酰辅酶 A 羧化酶 (ACC) 抑制剂（IC50:6 nM),具有抗菌活性，强烈抑制革兰氏阳性菌，但对革兰氏阴性菌的抑制效果较弱。
TP1663L	CysHHC10 acetate CysHHC10 acetate(1408311-03-4 free base)	Antibacterial	Microbiology/Virology
	CysHHC10 acetate 对革兰氏阳性菌和革兰氏阴性菌均具有抗菌活性，对大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌和表皮葡萄球菌的 MIC 分别为 10.1、20.2、2.5 和 1.3 mM。
T28229	Olanexidine hydrochloride OPB2045,OPB-2045,OPB-2045 HCl,OPB 2045	Antibacterial	Microbiology/Virology
	Olanexidine hydrochloride (OPB-2045 HCl) 对革兰氏阳性菌和革兰氏阴性菌具有杀菌活性。 Olanexidine hydrochloride 破坏金黄色葡萄球菌的膜完整性。
T22228	Tylvalosin tartrate 酒石酸乙酰异戊酰泰乐菌素,Acetylisovaleryltylosin Tartrate	Antibacterial; Antibiotic	Microbiology/Virology
	Tylvalosin tartrate (Acetylisovaleryltylosin Tartrate) 是一种对革兰氏阳性细菌具有抗性的大环内酯类抗生素。
T0967	Teicoplanin Antibiotic MDL-507,MDL-507,替考拉宁,Teichomycin	Antibacterial; Antibiotic	Microbiology/Virology
	Teicoplanin (MDL-507) 是一种半合成的糖肽抗生素, 可用于由革兰氏阳性菌引起的严重感染的相关研究。
T17021	Tebipenem LJC 11036	Antibiotic	Microbiology/Virology
	Tebipenem 是一种口服碳青霉烯类抗生素。它对革兰氏阳性和阴性细菌具有广谱活性。
T3247	Lysozyme from chicken egg white 鸡蛋清溶菌酶,溶菌酶,Lysozyme	Others; Antibacterial	Microbiology/Virology; Others
	Lysozyme from chicken egg white (Lysozyme) 是一种存在于鸡蛋清中的杀菌酶，它溶解革兰氏阳性菌。
T0897	Nitrofurazone NFZ,呋喃西林,Nitrofural,Furacilin	Dehydrogenase; Antibacterial; Glutathione reductase; Antibiotic	Metabolism; Microbiology/Virology; oxidation-reduction
	Nitrofurazone (Furacilin) 是一种抗生素。
T19709	Nitrocefin	Others	Others
	Nitrocefin 是 β-内酰胺酶的显色底物，当 β-内酰胺酶将 β-内酰胺环中的酰胺键水解后，Nitrocefin 的颜色会由黄色变为红色。它可用于 β-内酰胺酶耐药抗生素的研究。
T19860	Clavulanic Acid BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151	Antibacterial; Antifungal	Microbiology/Virology
	Clavulanic Acid(RX-10100) 是一种由生物体克拉维链霉菌产生的主要β-内酰胺类抗生素，是一种强效的细菌 β-内酰胺酶抑制剂，用于研究细菌引起的感染。Clavulanic Acid 具有广谱的生物活性，对多种革兰氏阳性和革兰氏阴性细菌均有活性。
T1001	Dicloxacillin Sodium hydrate Dicloxacillin sodium salt monohydrate,双氯西林钠,Dicloxacillin sodium monohydrate	Antibacterial; Antibiotic	Microbiology/Virology
	Dicloxacillin Sodium hydrate 是一种青霉素类窄谱β内酰胺抗生素，可研究革兰氏阳性菌感染。
T22408	Proflavine 吡啶-3,6-二胺,3,6-Diaminoacridine	Antibacterial	Microbiology/Virology
	Proflavine (3,6-Diaminoacridine) 是吖啶染料，可用作抗菌剂。它是 DNA 嵌入剂，能够阻滞Kir3.2孔。它用作与 Kir3.2 相关的神经系统疾病的研究。
T68137	Sanfetrinem GV104326	Antibiotic	Microbiology/Virology
	Sanfetrinem (GV104326) sodium 是一种新型可口服 β-内酰胺酶抗生素，对革兰氏阳性菌和革兰氏阴性菌显示出显著的抗菌活性，可用于研究细菌感染。
T7043	Cefotetan 头孢替坦,Apacef	Antibacterial; Antibiotic	Microbiology/Virology
	Cefotetan (Apacef) 是一种半合成的头霉素抗生素，能抑制细胞壁合成发挥杀菌作用。
T1492	Gemifloxacin mesylate LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate	DNA gyrase; Topoisomerase; Antibacterial	DNA Damage/DNA Repair; Microbiology/Virology
	Gemifloxacin mesylate (Gemifloxacin mesylate) 是一种喹诺酮类口服广谱抗菌剂，可研究轻中度肺炎和慢性支气管炎的急性细菌性发作。
T14951	Chlorhexidine digluconate	Apoptosis; Antibiotic	Apoptosis; Microbiology/Virology
	Chlorhexidine digluconate 是一种广谱防腐剂和消毒剂，具有广谱抗菌活性，抑制革兰氏阳性菌和革兰氏阴性菌，可诱导细胞坏死和凋亡，可用于研究细菌感染。
T22391	Omeprazole Sodium	P450; Proton pump; Antibacterial; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Omeprazole 是有效的质子泵抑制剂，在胃肠道疾病的研究中具有价值。它竞争性抑制CYP2C19活性，Ki 为 2 到 6 μM。它还抑制革兰氏阴性菌和革兰氏阳性菌生长。它是中性鞘磷脂酶的外泌体抑制剂。
T4998	Cefpodoxime proxetil	Antibacterial; Antibiotic	Microbiology/Virology
	Cefpodoxime Proxetil 是一种口服的广谱型抗生素。它与青霉素结合蛋白结合，抑制肽聚糖的合成，干扰细菌细胞壁的生物合成。
T9449	Nitrofural [(E)-(5-nitrofuran-2-yl)methylideneamino,(E)-2-((5-硝基呋喃-2-基)亚甲基)肼甲酰胺	Antibacterial	Microbiology/Virology
	Nitrofural 是 20 世纪已在临床应用中确立的硝基呋喃。 Nitrofural 在临床上对广泛的革兰氏阳性和革兰氏阴性细菌（包括许多常见的泌尿道病原体菌株）仍然有效。
T7858	Ceftezole sodium Celoslin,Falomesin,头孢替唑钠,Alomen	Anti-infection; Antibacterial; Antibiotic; Glucosidase	Metabolism; Microbiology/Virology
	Ceftezole sodium (Falomesin) 是一种广谱 cephem 抗生素，具有抑制多种革兰氏阳性菌和革兰氏阴性菌活性。它是一种α-葡萄糖苷酶抑制剂，具有体内抗糖尿病活性。
T0932	Cefixime FK-027,头孢克肟,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635	Antibacterial; Antibiotic	Microbiology/Virology
	Cefixime (FR-17027) 是一种头孢菌素类抗生素, 可研究一些细菌感染。
T0195	Secnidazole RP-14539,PM-185184,塞克硝唑	Antibiotic; Parasite	Microbiology/Virology
	Secnidazole (PM-185184) 是一种具有口服活性唑类抗生素，半衰期比甲硝唑更长。它有潜力研究细菌性阴道病。
T1060	Flumequine Flumigal,氟甲喹,R-802	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Flumequine (R-802) 是一种喹诺酮类抗生素，对革兰氏阳性菌和革兰氏阴性菌均有效。它是拓扑异构酶 II 抑制剂，抑制细胞分裂，IC50值为 15 μM (3.92 μg/mL)。
T0911	Cefotaxime sodium Cefotaxim sodium salt,头孢噻肟钠,Cefotaxime sodium salt,Cefotaxim (sodium salt),HR-756 (sodium salt)	Antibacterial; Antibiotic	Microbiology/Virology
	Cefotaxime sodium (Cefotaxim sodium salt) 是头孢类抗生素和耐内酰胺酶的头孢菌素，有抗革兰氏阳性菌和革兰氏阴性菌作用。
T124492	Imipenem N-Formimidoyl thienamycin,MK0787	Antifungal	Microbiology/Virology
	Imipenem (MK0787) 是一种噻吩霉素衍生物，属于抗生素类，具有抗菌活性，对革兰氏阳性和革兰氏阴性菌具有部分的抑制作用。Imipenem 可用于研究碳青霉烯类非易感性感染和铜绿假单胞菌生物膜感染。

化合物

Cat.No: T14391

Target: Antibacterial, Antibiotic

Cefpodoxime (free acid)

Cat.No: T4998L

Target: Others

Cat.No: T9680

Target: Antibacterial

Chloramphenicol palmitate

Cat.No: T20525

Target: Antibacterial, Antibiotic

Cat.No: T1008

Synonym: 头孢氨苄,Cefalexin,Cephacillin

Target: Antibacterial, Antibiotic

Mezlocillin Sodium

Cat.No: T6582

Synonym: 美洛西林钠,Baycipen

Target: Antibacterial, Antibiotic

Flucloxacillin sodium

Cat.No: T5006

Synonym: 氟氯西林钠,floxacillin sodium

Target: Antibacterial, Antibiotic

Cat.No: T3117

Synonym: 马波沙星,Marbofloxacine,Zeniquin,Marbocyl

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T0396

Synonym: 吡哌酸,Acido pipemidico

Target: Antibacterial, Antibiotic

Cat.No: T0116

Target: DNA gyrase, Antibacterial, Antibiotic

Cat.No: TP1444

Synonym: 蛙皮素 2

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T9066

Synonym: CI 934

Target: SARS-CoV

Cat.No: T7865

Synonym: 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine

Target: Others, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T2692

Synonym: Dalbavancin Impurity,达巴霉素杂质

Target: Antibacterial

Cat.No: T0133

Synonym: FK-482,头孢地尼,CI-983,PD 134393

Target: Glutathione Peroxidase, Antibacterial, Antibiotic

Anti gram-positive/negative bacteria agent 1

Cat.No: T73997

Cat.No: T20774

Synonym: A-56620,A 56620,A56620,沙拉沙星

Target: Antibacterial, Antibiotic

Cat.No: T1640

Synonym: Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867

Target: Topoisomerase, Antibacterial, Antibiotic

Fosmidomycin sodium salt

Cat.No: T11315

Synonym: FR-31564 sodium salt

Target: Antibiotic, Parasite

Flomoxef sodium

Cat.No: T11301L

Target: Others

Pefloxacin Mesylate

Cat.No: T0425

Synonym: Pefloxacinium mesylate,甲磺酸培氟沙星

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T11123

Target: Antibacterial, Antibiotic

Ticarcillin sodium

Cat.No: T6706

Synonym: Ticarpen hydrate,Aerugipen hydrate,替卡西林单钠盐单水合物,BRL 2288,AB 2288,Monapen

Target: Others, Antibacterial, Antibiotic

Magainin 1 acetate

Cat.No: TP1763L

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T4020

Synonym: ACT-179811,卡达唑利德

Target: Antibacterial, Antibiotic

Cat.No: T73054

Target: Acetyl-CoA Carboxylase, Antibiotic

CysHHC10 acetate

Cat.No: TP1663L

Synonym: CysHHC10 acetate(1408311-03-4 free base)

Target: Antibacterial

Olanexidine hydrochloride

Cat.No: T28229

Synonym: OPB2045,OPB-2045,OPB-2045 HCl,OPB 2045

Target: Antibacterial

Tylvalosin tartrate

Cat.No: T22228

Synonym: 酒石酸乙酰异戊酰泰乐菌素,Acetylisovaleryltylosin Tartrate

Target: Antibacterial, Antibiotic

Cat.No: T0967

Synonym: Antibiotic MDL-507,MDL-507,替考拉宁,Teichomycin

Target: Antibacterial, Antibiotic

Cat.No: T17021

Synonym: LJC 11036

Target: Antibiotic

Lysozyme from chicken egg white

Cat.No: T3247

Synonym: 鸡蛋清溶菌酶,溶菌酶,Lysozyme

Target: Others, Antibacterial

Cat.No: T0897

Synonym: NFZ,呋喃西林,Nitrofural,Furacilin

Target: Dehydrogenase, Antibacterial, Glutathione reductase, Antibiotic

Cat.No: T19709

Target: Others

Clavulanic Acid

Cat.No: T19860

Synonym: BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151

Target: Antibacterial, Antifungal

Dicloxacillin Sodium hydrate

Cat.No: T1001

Synonym: Dicloxacillin sodium salt monohydrate,双氯西林钠,Dicloxacillin sodium monohydrate

Target: Antibacterial, Antibiotic

Cat.No: T22408

Synonym: 吡啶-3,6-二胺,3,6-Diaminoacridine

Target: Antibacterial

Cat.No: T68137

Synonym: GV104326

Target: Antibiotic

Cat.No: T7043

Synonym: 头孢替坦,Apacef

Target: Antibacterial, Antibiotic

Gemifloxacin mesylate

Cat.No: T1492

Synonym: LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate

Target: DNA gyrase, Topoisomerase, Antibacterial

Chlorhexidine digluconate

Cat.No: T14951

Target: Apoptosis, Antibiotic

Omeprazole Sodium

Cat.No: T22391

Target: P450, Proton pump, Antibacterial, Autophagy

Cefpodoxime proxetil

Cat.No: T4998

Target: Antibacterial, Antibiotic

Cat.No: T9449

Synonym: [(E)-(5-nitrofuran-2-yl)methylideneamino,(E)-2-((5-硝基呋喃-2-基)亚甲基)肼甲酰胺

Target: Antibacterial

Ceftezole sodium

Cat.No: T7858

Synonym: Celoslin,Falomesin,头孢替唑钠,Alomen

Target: Anti-infection, Antibacterial, Antibiotic, Glucosidase

Cat.No: T0932

Synonym: FK-027,头孢克肟,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635

Target: Antibacterial, Antibiotic

Cat.No: T0195

Synonym: RP-14539,PM-185184,塞克硝唑

Target: Antibiotic, Parasite

Cat.No: T1060

Synonym: Flumigal,氟甲喹,R-802

Target: Topoisomerase, Antibacterial, Antibiotic

Cefotaxime sodium

Cat.No: T0911

Synonym: Cefotaxim sodium salt,头孢噻肟钠,Cefotaxime sodium salt,Cefotaxim (sodium salt),HR-756 (sodium salt)

Target: Antibacterial, Antibiotic

Cat.No: T124492

Synonym: N-Formimidoyl thienamycin,MK0787

Target: Antifungal

Cat. No.	Product Name	Target	Signaling Pathways
T2P2937	Nonacosane	Others; Antibacterial	Microbiology/Virology; Others
	Nonacosane 是从Baphia massaiensis 分离的，是一种由 29 个碳原子组成的直链烷烃，具有植物代谢物和挥发油成分的作用。
T8160	EGCG Octaacetate 乙酰化表没食子儿茶素没食子酸酯,乙酰化EGCG	Others; Antibacterial	Microbiology/Virology; Others
	EGCG Octaacetate 是表没食子儿茶素没食子酸酯的前药，对革兰氏阳性菌和革兰氏阴性菌有潜在抗菌可能。它可下调 PI3K/Akt/NFκB 磷酸化和 p65 乙酰化来降低促炎介质水平，减少小鼠结肠炎引起的结肠癌。
T0971	Dirithromycin Dirithromycinum,地红霉素,ASE 136,LY237216,Diritromicina,Dirithromycine	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Dirithromycin (LY237216) 是一种红霉素衍生物，是一种具有口服活性的半合成大环内酯类抗生素。它用于治疗许多不同类型的细菌感染。
T10662L	Calcimycin Antibiotic A-23187,离子载体(钙镁盐混合物),A-23187	Apoptosis; Antibacterial; Antibiotic; Autophagy; Antifungal	Apoptosis; Autophagy; Microbiology/Virology
	Calcimycin (A-23187) 是抗生素和二价阳离子离子载体。它抑制革兰氏阳性细菌和一些真菌生长，也抑制 ATP 酶的活性并解耦哺乳动物细胞的氧化磷酸化。它通过增加细胞内钙浓度诱导 Ca2+依赖性细胞死亡。
TQ0251	(Z)-2-decenoic acid (Z)-dec-2-enoic acid,(Z)-2-癸烯酸,cis-2-Decenoic acid,cis-dec-2-enoic acid	Others	Others
	(Z)-2-decenoic acid (cis-dec-2-enoic acid) 是一种由铜绿假单胞菌产生的不饱和脂肪酸。它能够诱导一系列革兰氏阴性细菌(包括铜绿假单胞菌)和革兰氏阳性细菌形成的生物膜发生分散反应。它能够抑制生物膜发育。
T8247	(+)-Aromadendrene	Anti-infection	Microbiology/Virology
	(+)-Aromadendrene 是一种天然产物，对革兰氏阳性菌和革兰氏阴性菌具有显着的抗菌活性。
T1665	Daptomycin 达托霉素,LY146032	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Daptomycin (LY146032) 是脂肽类抗生素，在体外快速灭活革兰氏阳性细菌。
T8062	Cefazedone Refosporen,头孢西酮	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Cefazedone (Refosporen) 是一种具有抗革兰氏阳性和革兰氏阴性菌活性的时间依赖性头孢菌素抗生素。
T1134	Clofoctol 叔辛酚氯,氯福克酚	Antibacterial; Antibiotic	Microbiology/Virology
	Clofoctol 是一种抗生素,，可研究革兰氏阳性菌感染。它仅对革兰氏阳性菌起作用, 可渗透入人类肺组织。
TN2279	Totarol (+)-Totarol,桃柁酚	Antibacterial; Antifection	Microbiology/Virology
	Totarol ((+)-Totarol) 对几种致病性革兰氏阳性细菌、结核分枝杆菌具有抗菌作用。
T5037	Midecamycin Antibiotic SF-837,Turimycin P3,Medecamycin A1,Rubimycin,麦迪霉素,Platenomycin B1,Espinomycin A	Antibacterial; Antibiotic	Microbiology/Virology
	Midecamycin (Medecamycin A1) 是乙酰氧基取代的大环内酯类抗生素，对革兰氏阳性和阴性菌有效。
T1306	Norfloxacin 氟哌酸,MK-0366,诺氟沙星	DNA gyrase; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Norfloxacin (MK-0366) 是广谱抗生素，能通过结合DNA 旋转酶抑制革兰氏阳性和阴性菌。
T1679	Thiostrepton Thiactin,Bryamycin,Alaninamide,硫链丝菌素	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Thiostrepton (Alaninamide) 是一种选择性抑制FOXM1的抗生素。FOXM1会与 YAP/TEAD 复合物结合，形成YAP/TEAD/FOXM1 复合物。
T8302	Ceftiofur	Antibacterial; Antibiotic	Microbiology/Virology
	Ceftiofur 是一种半合成抗生素，对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。
T0814L	Ampicillin Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,氨苄青霉素,Ampicillin acid	Antibacterial; Antibiotic	Microbiology/Virology
	Ampicillin (Aminobenzylpenicillin) 属于 β-内酰胺类抗生素，是一种半合成的青霉素。Ampicillin 具有杀菌活性，对各种革兰氏阳性细菌和革兰氏阴性细菌均有抑制活性。
T5S0814	Berberine hydrogen sulphate Berberine Bisulfate,硫酸氢黄连素,Umbellatine Sulfate	Antibacterial	Microbiology/Virology
	Berberine hydrogen sulphate (Umbellatine Sulfate) 是一种从几种植物中提取的生物碱，对多种微生物具有抗菌活性，包括革兰氏阳性和革兰氏阴性细菌、真菌和原生动物。
T5274	D-(+)-Phenyllactic acid D-3-苯乳酸,D-3-Phenyllactic acid	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-(+)-Phenyllactic acid (D-3-Phenyllactic acid) 是一种由白地霉分泌得到的抗菌剂，可抑制部分来自人类和食品的革兰氏阳性菌以及来自人类的革兰氏阴性菌。
T8504	Dianemycin Nanchangmycin (free acid)	Antibacterial; Antibiotic	Microbiology/Virology
	Dianemycin (Nanchangmycin (free acid)) 由Streptomyces nanchangensis 产生的一种聚醚抗生素，抑制革兰氏阳性菌。它也是一种针对 Zika 病毒的广谱抗病毒药物。
TN1651	Furanodiene	Apoptosis; PARP; Reactive Oxygen Species; Caspase; CDK; P-gp	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB; Proteases/Proteasome
	Furanodiene 是从姜黄中提取的一种萜类天然产物，可抑制外排转运蛋白Pgp 功能并降低 Pgp 蛋白水平。它通过抗血管生成和诱导ROS 产生，DNA 链断裂和细胞凋亡发挥抗癌作用。
T5003	Rifamycin sodium Rifamycin sodium salt,利福霉素钠	Antibacterial; Antibiotic	Microbiology/Virology
	Rifamycin sodium (Rifamycin sodium salt) salt 是从地中海曲霉或其突变体的发酵中分离出来的一种安沙霉素抗生素家族。它对革兰氏阳性菌和某些革兰氏阴性菌有抗生素活性。
T0906	Salinomycin 盐霉素,Procoxacin	Wnt/beta-catenin; Antibacterial	Cytoskeletal Signaling; Microbiology/Virology; Stem Cells
	Salinomycin (Procoxacin)是一种多醚类钾离子载体抗生素，特异性抑制革兰氏阳性细菌生长。Salinomycin 作为Wnt/β-连环蛋白信号通路的有效抑制剂，阻断Wnt诱导的LRP6磷酸化。此外，Salinomycin (Procoxacin)对人类癌症干细胞显示出选择性活性。
T12830	Sapienic acid sodium	Antibacterial	Microbiology/Virology
	Sapienic acid sodium，主要存在于皮肤和粘膜中的脂肪酸，对皮肤和口腔内的革兰氏阳性及阴性细菌展现出不同程度的抗菌效果。其对血链球菌、微生物链球菌与核纤梭菌的抗菌活性表现，MBC值分别为31.3 μg/mL、375.0 μg/mL与93.8 μg/mL。
T20643	Cefoxitin Rephoxitin,Cefoxitinum	Cell wall; Antibacterial; Antibiotic	Immunology/Inflammation; Microbiology/Virology
	Cefoxitin (Rephoxitin) 是一种广谱的、可口服的第二代头孢霉素类抗生素。Cefoxitin 干扰细菌细胞壁的合成。其活性谱包括革兰氏阴性和革兰氏阳性菌，通常用于腹腔感染、盆腔感染和某些类型的妇科感染等腹部，对厌氧菌具有高效性。
T0958	Penicillin G sodium salt 青霉素钠,Penicillin G Sodium,Benzylpenicillin sodium salt,Benzylpenicillin Sodium	GABA Receptor; Antibacterial; Antibiotic	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Penicillin G sodium(Benzylpenicillin sodium) salt 是一种 β-内酰胺类抗生素。
TN7231	Di-O-methylhonokiol Honokiol dimethyl ether	Antioxidant	oxidation-reduction
	Di-O-methylhonokiol (Honokiol dimethyl ether) 是Magnolia grandiflora L 的酚类成分，具有抗微生物活性，对革兰氏阳性和抗酸细菌和真菌具有显著的抗氧化活性。
T4S0867	Pogostone DHELWANGIN,广藿香酮	Apoptosis; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology
	Pogostone (DHELWANGIN) 是从薄荷中分离出，对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。
T2989	4-Hydroxybenzoic acid p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	4-Hydroxybenzoic acid (4-hydroxybenzoate) 是苯甲酸的酚衍生物，可抑制革兰氏阳性和革兰氏阴性菌，IC50值为160 μg/mL。
T8347	Rifamycin S	Reactive Oxygen Species; ROS; Antibacterial; Antibiotic	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Rifamycin S 是一种 DNA 依赖性 RNA 聚合酶抑制剂，是一种醌和一种针对革兰氏阳性细菌的抗生素试剂。它是涉及两个电子的可逆氧化还原系统的氧化形式。它能产生活性氧并抑制微粒体脂质过氧化，可研究肺结核和麻风病。
T1219	Sisomicin Sulfate 硫酸西索米星,Pathomycin,Extramycin,硫酸西索紫苏	Antibacterial; Antibiotic	Microbiology/Virology
	Sisomicin Sulfate (Pathomycin) 是由Micromonospora inyoensis 产生的一种广谱氨基糖苷类抗生素，对革兰氏阳性细菌有很大活性。
T3092	Nigericin sodium salt 尼日利亚菌素,尼日利亚菌素钠盐	Potassium Channel; NOD-like Receptor (NLR); Antibacterial; Antibiotic; NOD	Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology; NF-κB
	Nigericin sodium salt 属于抗生素，是一种 NLRP3 激活剂，也是一种阳离子离子载体。Nigericin sodium 可以触发 NALP3 炎性体的激活，可抑制高尔基体功能并抑制革兰氏阳性菌的生长。
T0819	Spiramycin Espiramicin,螺旋霉素,Sequamycin,Rovamycin,Provamycin,Formacidine	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Spiramycin (Rovamycin) 是一种由安博链霉菌产生的大环内酯类抗生素，具有抗细菌和弓形虫活性，并具有抗寄生虫作用。它由 16 个内酯环组成，其上附着 mycaminose，forosamine 和 mycarose 三种糖。
T4S1943	Kirenol 奇壬醇,奇任醇,Kirel	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	Kirenol (Kirel) 是分离自 Siegesbeckia orientalis 中的，具有抗氧化、抗炎、抗过敏、抗关节炎活性，可用于缓解疼痛的研究。
T26805	Bicyclomycin Bicozamycin
	Bicyclomycin is a broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium, Micrococcus luteusn.
TN4518	Meridinol	Antifection	Microbiology/Virology
	Meridinol has wide antimicrobial activity, includes against gram-positive and gram-negative bacteria and fungi.
T11551	Helvolic acid Fumigacin	Others	Others
	Helvolic acid, an antibiotic derived from Xylaria sp., exhibits effectiveness against Gram-positive bacteria.
TN6002	Crenatine 1-Ethyl-4-methoxy-β-carboline
	Crenatine possesses antibacterial activity, it is more effective against Gram-positive than Gram-negative bacteria.
T27024	Citromycetin Frequentic Acid,NSC-53584,NSC 53584,NSC53584
	Citromycetin is a fungal metabolite originally isolated from Australian P. frequentans. It has antibiotic activity against the Gram-negative bacteria V. cholerae and S. flexneri and the Gram-positive bacteria S. aureus.
TN1301	6,8-Diprenylgenistein 6,8-二异戊烯基金雀异黄素,鲁冰花	Antifection	Microbiology/Virology
	6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria.
T38176	Muramic acid
	Muramic acid is a prevalent constituent found in the cell walls of Gram-positive bacteria, serving as a distinguishing marker for such bacteria[1].
T4131	Arjunic acid	COX; Antifection	Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL.
TN6163	3-O-cis-p-Coumaroylmaslinic acid
	3-beta-O-(trans-p-Coumaroyl)maslinic acid shows antimicrobial activity on Gram-positive bacteria and yeasts.
TN4264	Isoapetalic acid 胡桐，海棠木	HIV Protease; Antifection	Microbiology/Virology; Proteases/Proteasome
	Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gram-positive bacteria(two Gram-positive bacteria, S. aureus and B. subtilis a
TN2502	1,5,6-Trihydroxyxanthone	Others	Others
	1,5,6-Trihydroxyxanthone exhibits antibacterial activity against Gram-positive bacteria.
T16673	Pseudouridimycin PUM	Others	Others
	Pseudouridimycin is a C-nucleoside analogue. Pseudouridimycin is an antibiotic and is a selective bacterial RNA polymerase (RNAP) inhibitor. It is effective against both Gram-negative and Gram-positive bacteria.
TN6148	3-O-trans-p-Coumaroylmaslinic acid
	3-beta-O-(trans-p-Coumaroyl)maslinic acid is a DNA polymerase B" inhibitor. It shows antimicrobial activity on Gram-positive bacteria and yeasts.
T32924	Lucidin ethyl ether
	Ibericin 是一种从Prismatomeris filamentosa 根中分离得到的蒽醌代谢产物，对革兰氏阳性菌和革兰氏阴性菌具有一定的抗菌活性。
TN5930	Ocotillone
	Ocotillone has potent antibacterial activity against Gram-negative bacteria, P. aeruginosa and S. typhimurium, that are without hemolytic activity, whereas it has weak antimicrobial activity against Gram-positive bacteria and fungi. Ocotillone shows only
T71909	Kumbicin C
	Kumbicin C inhibits the growth of NS-1 mouse myeloma cells (IC50 = 0.74 μg/ml) and the growth of the Gram-positive bacteria B. subtilis (MIC = 1.6 μg/ml).
T10455	Bafilomycin B1 巴佛洛霉素 B1	Others	Others
	Bafilomycin B1, a macrolide antibiotic isolated from Streptomyces sp, acts as an inhibitor of K+-dependent ATPase of E. coli. It also inhibits Gram-positive bacteria and fungi.
T8261	Ceftazidime Pentahydrate 头孢他啶五水合物,头孢他啶	Antibacterial; Antibiotic	Microbiology/Virology
	Ceftazidime pentahydrate 是一种β-内酰胺类抗菌剂，对革兰氏阳性和革兰氏阴性需氧细菌有广谱活性，可静脉内或肌肉给药。它对肠杆菌科特别有效，对大多数 β-内酰胺酶具有抗水解作用。
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天然产物

Cat.No: T2P2937

Target: Others, Antibacterial

EGCG Octaacetate

Cat.No: T8160

Synonym: 乙酰化表没食子儿茶素没食子酸酯,乙酰化EGCG

Target: Others, Antibacterial

Cat.No: T0971

Synonym: Dirithromycinum,地红霉素,ASE 136,LY237216,Diritromicina,Dirithromycine

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T10662L

Synonym: Antibiotic A-23187,离子载体(钙镁盐混合物),A-23187

Target: Apoptosis, Antibacterial, Antibiotic, Autophagy, Antifungal

(Z)-2-decenoic acid

Cat.No: TQ0251

Synonym: (Z)-dec-2-enoic acid,(Z)-2-癸烯酸,cis-2-Decenoic acid,cis-dec-2-enoic acid

Target: Others

(+)-Aromadendrene

Cat.No: T8247

Target: Anti-infection

Cat.No: T1665

Synonym: 达托霉素,LY146032

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T8062

Synonym: Refosporen,头孢西酮

Target: Others, Antibacterial, Antibiotic

Cat.No: T1134

Synonym: 叔辛酚氯,氯福克酚

Target: Antibacterial, Antibiotic

Cat.No: TN2279

Synonym: (+)-Totarol,桃柁酚

Target: Antibacterial, Antifection

Cat.No: T5037

Synonym: Antibiotic SF-837,Turimycin P3,Medecamycin A1,Rubimycin,麦迪霉素,Platenomycin B1,Espinomycin A

Target: Antibacterial, Antibiotic

Cat.No: T1306

Synonym: 氟哌酸,MK-0366,诺氟沙星

Target: DNA gyrase, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic

Cat.No: T1679

Synonym: Thiactin,Bryamycin,Alaninamide,硫链丝菌素

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T8302

Target: Antibacterial, Antibiotic

Cat.No: T0814L

Synonym: Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,氨苄青霉素,Ampicillin acid

Target: Antibacterial, Antibiotic

Berberine hydrogen sulphate

Cat.No: T5S0814

Synonym: Berberine Bisulfate,硫酸氢黄连素,Umbellatine Sulfate

Target: Antibacterial

D-(+)-Phenyllactic acid

Cat.No: T5274

Synonym: D-3-苯乳酸,D-3-Phenyllactic acid

Target: Endogenous Metabolite, Antibacterial

Cat.No: T8504

Synonym: Nanchangmycin (free acid)

Target: Antibacterial, Antibiotic

Cat.No: TN1651

Target: Apoptosis, PARP, Reactive Oxygen Species, Caspase, CDK, P-gp

Rifamycin sodium

Cat.No: T5003

Synonym: Rifamycin sodium salt,利福霉素钠

Target: Antibacterial, Antibiotic

Cat.No: T0906

Synonym: 盐霉素,Procoxacin

Target: Wnt/beta-catenin, Antibacterial

Sapienic acid sodium

Cat.No: T12830

Target: Antibacterial

Cat.No: T20643

Synonym: Rephoxitin,Cefoxitinum

Target: Cell wall, Antibacterial, Antibiotic

Penicillin G sodium salt

Cat.No: T0958

Synonym: 青霉素钠,Penicillin G Sodium,Benzylpenicillin sodium salt,Benzylpenicillin Sodium

Target: GABA Receptor, Antibacterial, Antibiotic

Di-O-methylhonokiol

Cat.No: TN7231

Synonym: Honokiol dimethyl ether

Target: Antioxidant

Cat.No: T4S0867

Synonym: DHELWANGIN,广藿香酮

Target: Apoptosis, Antibacterial, Autophagy

4-Hydroxybenzoic acid

Cat.No: T2989

Synonym: p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate

Target: Endogenous Metabolite, Antibacterial

Cat.No: T8347

Target: Reactive Oxygen Species, ROS, Antibacterial, Antibiotic

Sisomicin Sulfate

Cat.No: T1219

Synonym: 硫酸西索米星,Pathomycin,Extramycin,硫酸西索紫苏

Target: Antibacterial, Antibiotic

Nigericin sodium salt

Cat.No: T3092

Synonym: 尼日利亚菌素,尼日利亚菌素钠盐

Target: Potassium Channel, NOD-like Receptor (NLR), Antibacterial, Antibiotic, NOD

Cat.No: T0819

Synonym: Espiramicin,螺旋霉素,Sequamycin,Rovamycin,Provamycin,Formacidine

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T4S1943

Synonym: 奇壬醇,奇任醇,Kirel

Target: Wnt/beta-catenin

Cat.No: T26805

Synonym: Bicozamycin

Cat.No: TN4518

Target: Antifection

Cat.No: T11551

Synonym: Fumigacin

Target: Others

Cat.No: TN6002

Synonym: 1-Ethyl-4-methoxy-β-carboline

Cat.No: T27024

Synonym: Frequentic Acid,NSC-53584,NSC 53584,NSC53584

6,8-Diprenylgenistein

Cat.No: TN1301

Synonym: 6,8-二异戊烯基金雀异黄素,鲁冰花

Target: Antifection

Cat.No: T38176

Cat.No: T4131

Target: COX, Antifection

3-O-cis-p-Coumaroylmaslinic acid

Cat.No: TN6163

Isoapetalic acid

Cat.No: TN4264

Synonym: 胡桐，海棠木

Target: HIV Protease, Antifection

1,5,6-Trihydroxyxanthone

Cat.No: TN2502

Target: Others

Pseudouridimycin

Cat.No: T16673

Synonym: PUM

Target: Others

3-O-trans-p-Coumaroylmaslinic acid

Cat.No: TN6148

Lucidin ethyl ether

Cat.No: T32924

Cat.No: TN5930

Cat.No: T71909

Cat.No: T10455

Synonym: 巴佛洛霉素 B1

Target: Others

Ceftazidime Pentahydrate

Cat.No: T8261

Synonym: 头孢他啶五水合物,头孢他啶

Target: Antibacterial, Antibiotic

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