Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mezlocillin Sodium (Baycipen) 是一种青霉素 β-内酰胺类抗生素,用于治疗由易感染微生物引起的细菌感染。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 122 | 现货 | ||
10 mg | ¥ 158 | 现货 | ||
25 mg | ¥ 235 | 现货 | ||
50 mg | ¥ 372 | 现货 | ||
100 mg | ¥ 538 | 现货 | ||
200 mg | ¥ 787 | 现货 | ||
500 mg | ¥ 1,290 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 397 | 现货 |
产品描述 | Mezlocillin Sodium (Baycipen) is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. |
体外活性 | Mezlocillin sodium has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of mezlocillin results from the inhibition of cell wall synthesis and is mediated through mezlocillin binding to penicillin binding proteins (PBPs). Mezlocillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Mezlocillin inhibits the third and last stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that mezlocillin interferes with an autolysin inhibitor. Unlike many other penicillins, mezlocillin is either extensively metabolized or is subject to biliary excretion, as only about 50% of the dose is accounted for in normal urine. [1] |
别名 | 美洛西林钠, Baycipen |
分子量 | 561.56 |
分子式 | C21H25N5O8S2·Na |
CAS No. | 42057-22-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 92 mg/mL (163.8 mM)
DMSO: 93 mg/mL (165.6 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O / DMSO | 1 mM | 1.7808 mL | 8.9038 mL | 17.8075 mL | 44.5188 mL |
5 mM | 0.3562 mL | 1.7808 mL | 3.5615 mL | 8.9038 mL | |
10 mM | 0.1781 mL | 0.8904 mL | 1.7808 mL | 4.4519 mL | |
20 mM | 0.089 mL | 0.4452 mL | 0.8904 mL | 2.2259 mL | |
50 mM | 0.0356 mL | 0.1781 mL | 0.3562 mL | 0.8904 mL | |
100 mM | 0.0178 mL | 0.089 mL | 0.1781 mL | 0.4452 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Mezlocillin Sodium 42057-22-7 Microbiology/Virology Antibacterial Antibiotic BAY-f 1353 bacterial infection gram-positive bacteria 美洛西林钠 Mezlocillin Baycipen gram-negative bacteria Bacterial inhibit Inhibitor inhibitor