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66

抑制剂 & 化合物

6

天然产物

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Cat. No. Product Name Target Signaling Pathways
T3971 CASIN

Pirl1-related Compound 2

CDK; STAT; Ras Cell Cycle/Checkpoint; GPCR/G Protein; JAK/STAT signaling; MAPK; Stem Cells
CASIN (Pirl1-related Compound 2) 是选择性GTPase Cdc42抑制剂,IC50值是 2 uM。
T27617 Inz-1

P450 Metabolism
Inz-1 是一种有效的真菌特异性线粒体细胞色素 bc1 抑制剂,对酵母和人类的 IC50 分别为 8.092 和 45.320 μM。 Inz-1 可逆转氟康唑或其他三唑类抗真菌药对致病性真菌白色念珠菌的耐药性。
T2620 G-749

G749

Apoptosis; FLT; c-RET; TAM Receptor; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
G-749 是一种新型 FLT3 抑制剂,对 FLT3 野生型和突变体有持续的抑制作用,IC50值分别为 0.4 nM 和 0.6 nM。它可用于急性髓系白血病的耐药研究。
T16339 Norverapamil hydrochloride

(±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米

Calcium Channel; P-gp; Drug Metabolite Membrane transporter/Ion channel; Metabolism; Neuroscience
Norverapamil hydrochloride (D591 hydrochloride) 是 Verapamil 的 N-去甲基代谢物,是 L 型钙通道阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。
T15168 DRF-1042

Others Others
DRF-1042 acts to inhibit DNA topoisomerase I. DRF-1042 displays perfect anticancer activity against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype.
T6018 Zosuquidar trihydrochloride

唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride

P-gp Membrane transporter/Ion channel; Neuroscience
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) 是一种P-糖蛋白抑制剂,Ki 值为 59 nM。
T6287 Tariquidar

XR9576,他立喹达

P-gp Membrane transporter/Ion channel; Neuroscience
Tariquidar (XR9576) 是一种特异性有效的P-糖蛋白抑制剂,Kd 为 5.1 nM。
T7861 Flumatinib mesylate

甲磺酸氟马替尼/氟马替尼,HHGV678 mesylate,甲磺酸氟马替尼

Bcr-Abl; PDGFR; c-Kit Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Flumatinib mesylate (HHGV678 mesylate) 是一种具有口服活性的选择性Bcr-Abl 抑制剂,能够作用于 c-Abl (IC50:1.2 nM),PDGFRβ (IC50:307.6 nM) 和 c-Kit (IC50:665.5 nM)。
T0002 Ethamsylate

Cyclonamine,Etamsylate,酚磺乙胺,Dicynene,Aglumin

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Ethamsylate (Dicynene) 通常用作止血药,增加毛细血管内皮阻力和血小板粘附,抑制前列腺素的生物合成和作用。
T25770 116-9e

MAL-2-11B,MAL2-11B,MAL211B,MAL 2 11B,MAL2 11B

Virus Protease Microbiology/Virology
116-9e (MAL2-11B) 是一种有效的 Hsp70 共伴侣 DNAJA1 抑制剂,具有抗病毒,抑制猿猴病毒40 (SV40) 的复制,抑制肿瘤抗原 (TAg) 内源性 ATP 酶活性和 TAg 介导的 Hsp70 激活。116-9e 可用于研究癌症耐药性。
T3335 Darunavir Ethanolate

地瑞那韦乙醇盐,UIC 94017,Darunavir Ethanolate,TMC114,达芦那韦乙醇

HIV Protease Microbiology/Virology; Proteases/Proteasome
Darunavir Ethanolate (UIC 94017) 是一种HIV 蛋白酶抑制剂,可以用于 HIV/AIDS 的相关研究。对野生型 HIV-1 蛋白酶的Ki 值为1 nM。
T36375 Ralaniten triacetate

Ralaniten triacetate (EPI-506) is a novel pro-drug of Ralaniten, functioning as an orally active inhibitor of the androgen receptor (AR) N-terminal domain (NTD). Its remarkable first-in-class status signifies its unique nature within the field. This compound exhibits significant efficacy against various AR species, including AR-v7, which are associated with resistance. Notably, Ralaniten triacetate's activity encompasses full-length AR as well [1][2].
T1649 Tenofovir

替诺福韦,泰诺福韦,PMPA,TDF,GS 1278

HBV; HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
Tenofovir (GS 1278) 是一种核苷酸逆转录酶抑制剂,可研究 HIV 和慢性乙型肝炎。
T2324 Darunavir

地瑞那韦,达芦那韦,TMC114

HIV Protease Microbiology/Virology; Proteases/Proteasome
Darunavir (TMC114) 是一种 HIV 蛋白酶抑制剂,用于治疗艾滋病和 HIV 感染。 由于单独使用时会出现抗病毒药物耐药性,因此与其他抗 HIV 药物联合使用。
T8488 GMB-475

Bcr-Abl Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
GMB-475 是一种基于PROTAC 的BCR-ABL1酪氨酸激酶降解剂,克服了BCR-ABL1依赖的耐药性。 GMB-475 靶向 BCR-ABL1 蛋白并募集 E3 连接酶 Von Hippel Lindau (VHL)。导致泛素化和随后的致癌融合蛋白降解
T2328 Radotinib

IY-5511,Supect,雷度替尼

Bcr-Abl Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Radotinib (IY-5511) 有时被称为 IY5511,是一种用于治疗不同类型 Y 的药物,最显着的是费城染色体阳性 (Ph+) 慢性粒细胞白血病 (CML) 对其他酪氨酸激酶 Bcr-Abl 的耐药性或不耐受性抑制剂
T1496 Amiodarone hydrochloride

盐酸胺碘酮,Amiodar,Amiodarone HCl,Nexterone

Potassium Channel; Adrenergic Receptor; Autophagy Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
Amiodarone hydrochloride (Amiodarone HCl) 是一种抗心绞痛和 III 类抗心律失常药物,通过抑制钾通道和电压门控钠通道来增加心室和心房肌肉作用的持续时间,可导致心率和血管阻力降低。它通过成纤维细胞中的 ERK1/2和 p38 MAPK 信号传导诱导细胞增殖和肌成纤维细胞分化,可研究室上性和室性心律失常。
T31019 CP 117227

CP117227,CP-117227

CP 117227 is a multi-drug resistance regulator.
T24785 S-Fcme

S Fcme,SFcme

S-Fcme is an activator of multidrug resistance transporter that acts by stimulating the multidrug resistance transporter ATPase activity and competing for drug binding.
T25820 ML358

ML-358,ML 358

ML358 is a selective SKN-1 pathway inhibitor involved in drug detoxification and resistance in nematodes.
T24130 HCI-2184

HCI2184,HCI 2184

HCI-2184 is an inhibitor of AXL kinase and Nek2 that acts by successfully mitigating drug resistance in bortezomib-resistant multiple myeloma.
T13725 Hsp90-Cdc37-IN-1

Others Others
Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.
T24005 DJ101

DJ-101,DJ 101

DJ101is an effective and metabolically stable inhibitor of tubulin. It can circumvent the drug efflux pumps responsible for multidrug resistance of existing tubulin inhibitors.
T30767 CB-181963

CB 181963,CB181963,UNII-6784994L0W,CAB 175

CB-181963, a new cephalosporin, is an effective antistaphylococcal drug, showing excellent activity against the resistance of MRSA strains to other cephalosporins in planktonic and biofilm cultures.
T15587 Inz-5

Others Others
Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.
T23574 (+)-Carbovir triphosphate

LCBVTP,L CBVTP,L-CBVTP

(+)-Carbovir triphosphate is an active metabolite of Abacavir. It was used to study the molecular mechanism of inhibition and drug resistance for HIV-1 reverse transcriptase.
T25633 Lascufloxacin HCl

KRP-AM1977X,KRP-AM-1977,KRP-AM1977Y,KRP-AM 1977,KRP-AM1977,Lascufloxacin hydrochloride

Lascufloxacin (KRP-AM-1977) is a potent antibacterial drug candidate. It exhibited the most potent activity against gram-positive bacteria among the quinolones tested. Lascufloxacin showed incomplete cross-resistance against existing quinolone-resistant s
T26733 B 746

B-746,B746

B 746 is an antibacterial agent primarily. B 746 is used in therapy for leprosy and Mycobacterium avium infections as well as against Mycobacterium tuberculosis, including those with multi-drug resistance.
T11115 Duocarmycin GA

Others Others
Duocarmycin GA, an antibody drug conjugate (ADC) toxin and a DNA alkylating agent, effectively targets and binds in the minor groove of DNA. It is particularly potent against multi-drug resistant cell lines, offering a strategic approach in combating resistance.
T34270 Razupenem

SMP601,SMP 601,PTZ601,PTZ 601,PTZ-601,SMP-601

Razupenem ( SMP-601, PTZ601) is a broad-spectrum injectable antibiotic derived from the carbapenem subgroup of β-lactam antibiotics. It has been developed as an alternative drug against bacteria that have developed antibiotic resistance to commonly used a
T26413 A 30312

A-30312,A30312

A 30312 is a fused indole, which overcomes multidrug resistance in P388/Adr cells in vitro. It potentiates the cytotoxicity of the antitumor drugs Adriamycin, vincristine and vinblastine in multidrug-resistant cells with no effect on drug-sensitive parent P388 cells.
T21323 Picoplatin

NX 473,AMD-473,AMD473,NX-473,NX473,AMD 473

Picoplatin has a broad spectrum of antineoplastic activity and is designed to overcome platinum drug resistance. Picoplatin alkylates DNA, forming both intra- and inter-strand cross-linkages, resulting in the inhibition of DNA replication and transcriptio
T61485 S07-2010

S07-2010 is a potent pan-AKR1C inhibitor, effectively inhibiting AKR1C3, AKR1C4, AKR1C1, and AKR1C2 with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM, respectively. This compound induces apoptosis in A549/DDP cells and enhances the cytotoxicity of chemotherapeutic agents in drug-resistant cells, making it a viable option for combating drug resistance. Furthermore, S07-2010 significantly inhibits the proliferation of drug-resistant cells [1].
T74982 Akt3 degrader 1

Akt3degrader 1 (化合物 12l) 是一种选择性的Akt3降解剂,能克服Osimertinib 诱导的 H1975OR NSCLC 细胞的抗性。Akt3degrader 1 还具有抗增殖活性,能显著抑制小鼠体内肿瘤的生长。Akt3degrader 1 可用于耐药性非小细胞肺癌的研究。
T71865 DSM43

DSM43 is a dihydroorotate dehydrogenase (DHODH) inhibitor. Malaria puts at risk nearly half the world's population and causes high mortality in sub-Saharan Africa, while drug resistance threatens current therapies. The pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH) is a validated target for malaria treatmen
T70760 NVP018

NVP018, also known as BC 556, is a potent inhibitor of hepatitis B virus, hepatitis C virus (HCV), and HIV-1 replication, shows minimal inhibition of major drug transporters, and has a high barrier to generation of both HCV and HIV-1 resistance..
T4047L Bisantrene HCl

CL216942,CL-216942,NSC-337766,CL 216942

Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts and disrupts the configuration of
T70774 Clavicoronic acid

Clavicoronic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins.
T14945 CH-0793076

TP3076

Topoisomerase DNA Damage/DNA Repair
CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein). CH-0793076 inhibits DNA topoisomerase I (IC50: 2.3 μM).
T80245 LL-37(17-32)

LL-37(17-32)为具有生物活性的肽段,为LL-37抗菌肽C末端结构域源自的活性片段。报道显示,LL-37(17-32)能逆转癌细胞系中ABCG2介导的多药耐药性。
T61511 S07-2005 (racemic)

S07-2005 racemic is a chemically potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3), with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. Due to its inhibitory properties, it exhibits potential as a chemotherapeutic potentiator, specifically in the context of overcoming drug resistance in cancer [1].
T82705 Clovibactin

Antibiotic Microbiology/Virology
Clovibactin为一种新型抗生素,能有效消灭耐药细菌病原体,且未观察到耐药性。该化合物能从未培养的土壤细菌中提取。
T36600 Cefsulodin (sodium salt hydrate)

Cefsulodin is a β-lactam antibiotic that lyses actively-growingE. coliby binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.1Cefsulodin has been used in combination with other β-lactam antibiotics, such as cefazolin as a strategy to circumvent drug resistance.2
T64020 EGFR-IN-17

EGFR-IN-17 是有效的、选择性的表皮生长因子受体(EGFR)抑制剂,其 IC50 值为0.0002 μM,能够用于克服 C797S 介导的耐药性。
T68866 Ceftolozane

Ceftolozane, also known as FR-264,205 and CXA-101; is an antibiotic drug from the cephalosporin family, approved for the treatment of infections with gram-negative bacteria, or gram-positive bacteria. Ceftolozane is of great benefit due to its ability to target bacteria that have become resistant to conventional antibiotics. Ceftolozane is combined with the β-lactamase inhibitor tazobactam, as multi-drug resistant bacterial infections will generally show resistance to all β-lactam antibiotics un...
TP2222 APTSTAT3-9R

Others Others
APTSTAT3-9R-9R is a STAT3 inhibitor (Ki: 231 nmol/L). STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target for various diseases. However, though
T61108 YXL-13

YXL-13 is a highly effective inhibitor of Pseudomonas aeruginosa (PAO1), with an IC50 value of 3.686 μM. It effectively hinders the expression of virulence factors and inhibits biofilm formation in PAO1. Moreover, YXL-13 significantly diminishes both the pathogenicity and drug resistance of PAO1 by inhibiting the quorum sensing (QS) system. Thus, YXL-13 holds great potential for studying antibacterial properties [1].
T78747 DiPT-4

Topoisomerase DNA Damage/DNA Repair
DiPT-4为一种TOP1/PARP1双重抑制剂,可引发癌细胞大量DNA双链断裂(DSB)、细胞周期阻滞及凋亡。DiPT-4具有研究癌症耐药性克服潜力。
T61370 DNA-PK-IN-6

DNA-PK-IN-6, a robust DNA-PK inhibitor, effectively hampers the activity of DNA-PKcs, thereby significantly impairing the DNA repair mechanism in tumors and instigating apoptosis in cells. Additionally, DNA-PK-IN-6 amplifies the responsiveness of tumor tissues to radiotherapy, overcomes the challenge of drug resistance, and augments its inhibitory impact on a diverse range of solid and hematological tumors[1].
T71275 CID16725315

Thiocarbazate, also known as CID16725315, is an inhibitor of human cathepsin L. Inhibition of cathepsin L thus holds promise for therapeutic intervention for both SARS-CoV and Ebola virus infection. With respect to the development of antiviral agents, inhibitors of human cathepsin L are not subject to resistance because of rapid mutations of the viral genome. Cathepsin L is therefore an attractive target for drug development.

化合物

CASIN
Cat.No: T3971
Synonym: Pirl1-related Compound 2
Target: CDK, STAT, Ras
Inz-1
Cat.No: T27617
Synonym:
Target: P450
G-749
Cat.No: T2620
Synonym: G749
Target: Apoptosis, FLT, c-RET, TAM Receptor, Aurora Kinase
Norverapamil hydrochloride
Cat.No: T16339
Synonym: (±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米
Target: Calcium Channel, P-gp, Drug Metabolite
DRF-1042
Cat.No: T15168
Synonym:
Target: Others
Zosuquidar trihydrochloride
Cat.No: T6018
Synonym: 唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride
Target: P-gp
Tariquidar
Cat.No: T6287
Synonym: XR9576,他立喹达
Target: P-gp
Flumatinib mesylate
Cat.No: T7861
Synonym: 甲磺酸氟马替尼/氟马替尼,HHGV678 mesylate,甲磺酸氟马替尼
Target: Bcr-Abl, PDGFR, c-Kit
Ethamsylate
Cat.No: T0002
Synonym: Cyclonamine,Etamsylate,酚磺乙胺,Dicynene,Aglumin
Target: Prostaglandin Receptor
116-9e
Cat.No: T25770
Synonym: MAL-2-11B,MAL2-11B,MAL211B,MAL 2 11B,MAL2 11B
Target: Virus Protease
Darunavir Ethanolate
Cat.No: T3335
Synonym: 地瑞那韦乙醇盐,UIC 94017,Darunavir Ethanolate,TMC114,达芦那韦乙醇
Target: HIV Protease
Ralaniten triacetate
Cat.No: T36375
Synonym:
Target:
Tenofovir
Cat.No: T1649
Synonym: 替诺福韦,泰诺福韦,PMPA,TDF,GS 1278
Target: HBV, HIV Protease, Reverse Transcriptase
Darunavir
Cat.No: T2324
Synonym: 地瑞那韦,达芦那韦,TMC114
Target: HIV Protease
GMB-475
Cat.No: T8488
Synonym:
Target: Bcr-Abl
Radotinib
Cat.No: T2328
Synonym: IY-5511,Supect,雷度替尼
Target: Bcr-Abl
Amiodarone hydrochloride
Cat.No: T1496
Synonym: 盐酸胺碘酮,Amiodar,Amiodarone HCl,Nexterone
Target: Potassium Channel, Adrenergic Receptor, Autophagy
CP 117227
Cat.No: T31019
Synonym: CP117227,CP-117227
Target:
S-Fcme
Cat.No: T24785
Synonym: S Fcme,SFcme
Target:
ML358
Cat.No: T25820
Synonym: ML-358,ML 358
Target:
HCI-2184
Cat.No: T24130
Synonym: HCI2184,HCI 2184
Target:
Hsp90-Cdc37-IN-1
Cat.No: T13725
Synonym:
Target: Others
DJ101
Cat.No: T24005
Synonym: DJ-101,DJ 101
Target:
CB-181963
Cat.No: T30767
Synonym: CB 181963,CB181963,UNII-6784994L0W,CAB 175
Target:
Inz-5
Cat.No: T15587
Synonym:
Target: Others
(+)-Carbovir triphosphate
Cat.No: T23574
Synonym: LCBVTP,L CBVTP,L-CBVTP
Target:
Lascufloxacin HCl
Cat.No: T25633
Synonym: KRP-AM1977X,KRP-AM-1977,KRP-AM1977Y,KRP-AM 1977,KRP-AM1977,Lascufloxacin hydrochloride
Target:
B 746
Cat.No: T26733
Synonym: B-746,B746
Target:
Duocarmycin GA
Cat.No: T11115
Synonym:
Target: Others
Razupenem
Cat.No: T34270
Synonym: SMP601,SMP 601,PTZ601,PTZ 601,PTZ-601,SMP-601
Target:
A 30312
Cat.No: T26413
Synonym: A-30312,A30312
Target:
Picoplatin
Cat.No: T21323
Synonym: NX 473,AMD-473,AMD473,NX-473,NX473,AMD 473
Target:
S07-2010
Cat.No: T61485
Synonym:
Target:
Akt3 degrader 1
Cat.No: T74982
Synonym:
Target:
DSM43
Cat.No: T71865
Synonym:
Target:
NVP018
Cat.No: T70760
Synonym:
Target:
Bisantrene HCl
Cat.No: T4047L
Synonym: CL216942,CL-216942,NSC-337766,CL 216942
Target:
Clavicoronic acid
Cat.No: T70774
Synonym:
Target:
CH-0793076
Cat.No: T14945
Synonym: TP3076
Target: Topoisomerase
LL-37(17-32)
Cat.No: T80245
Synonym:
Target:
S07-2005 (racemic)
Cat.No: T61511
Synonym:
Target:
Clovibactin
Cat.No: T82705
Synonym:
Target: Antibiotic
Cefsulodin (sodium salt hydrate)
Cat.No: T36600
Synonym:
Target:
EGFR-IN-17
Cat.No: T64020
Synonym:
Target:
Ceftolozane
Cat.No: T68866
Synonym:
Target:
APTSTAT3-9R
Cat.No: TP2222
Synonym:
Target: Others
YXL-13
Cat.No: T61108
Synonym:
Target:
DiPT-4
Cat.No: T78747
Synonym:
Target: Topoisomerase
DNA-PK-IN-6
Cat.No: T61370
Synonym:
Target:
CID16725315
Cat.No: T71275
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3S2381 Perillene

3-Isohexenylfuran,紫苏烯,Perillen

Others; Antibacterial Microbiology/Virology; Others
Perillene (3-Isohexenylfuran) 是促进肠蠕动的药物中的活性成分,它对金黄色葡萄球菌和大肠杆菌具有很强的抗药性。
T3895 Polyphyllin I

重楼皂苷I,重楼皂甙

Apoptosis; Akt; JNK; PDK; mTOR; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Polyphyllin I 是从七叶一枝花中提取的生物活性成分,具有很强的抗肿瘤活性。它是 JNK 信号通路的激活剂,也是 PDK1/Akt/mTOR 信号传导的抑制剂。它诱导自噬,G2/M 期阻滞和细胞凋亡。
T4S1419 (±)-Praeruptorin A

Praeruptorin A,(±)-白花前胡甲素,白花前胡甲素,(-)-Praeruptorin A

p38 MAPK; Calcium Channel; Akt Cytoskeletal Signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
(±)-Praeruptorin A 是来自白花前胡的干燥根中的一种主要成分,用于研究伴有厚痰和呼吸困难的咳嗽,非天生性咳嗽和上呼吸道感染。它是顺式-内酯 (CKL) 的二酯化产物,可作为 Ca2+-反流阻滞剂,用于高血压的研究。
T40924 Tellimagrandin II

Eugeniin

Tellimagrandin II (Eugeniin) is the initial intermediate in the 4 C 1 -glucose derived series of ellagitannins. Additionally, it possesses the ability to inhibit antibiotic resistance exhibited by drug-resistant Staphylococcus aureus.
TN2229 Soyasaponin Ac

Others Others
Soyasaponin Ac can decrease the drug resistance via EMT pathway and weaken the migration ability of ovarian cancer cells.
TN3911 Ecdysterone 2,3:20,22-diacetonide

Others Others
Due to the multi-drug resistance reversal activity of the less polar ecdysteroids, several new products( including 20-hydroxyecdysone,20-hydroxyecdysone 2,3;20,22-diacetonide) are promising for being tested against various cancer cell lines.

天然产物

Perillene
Cat.No: T3S2381
Synonym: 3-Isohexenylfuran,紫苏烯,Perillen
Target: Others, Antibacterial
Polyphyllin I
Cat.No: T3895
Synonym: 重楼皂苷I,重楼皂甙
Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy
(±)-Praeruptorin A
Cat.No: T4S1419
Synonym: Praeruptorin A,(±)-白花前胡甲素,白花前胡甲素,(-)-Praeruptorin A
Target: p38 MAPK, Calcium Channel, Akt
Tellimagrandin II
Cat.No: T40924
Synonym: Eugeniin
Target:
Soyasaponin Ac
Cat.No: TN2229
Synonym:
Target: Others
Ecdysterone 2,3:20,22-diacetonide
Cat.No: TN3911
Synonym:
Target: Others
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