Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DRF-1042 acts to inhibit DNA topoisomerase I. DRF-1042 displays perfect anticancer activity against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 2,570 | 现货 | ||
25 mg | ¥ 13,300 | 现货 | ||
50 mg | ¥ 17,400 | 现货 | ||
100 mg | ¥ 26,900 | 现货 |
产品描述 | DRF-1042 acts to inhibit DNA topoisomerase I. DRF-1042 displays perfect anticancer activity against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype. |
体外活性 | DRF-1042 shows superior lactone stability and good in vitro anticancer activity. It can against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype [2]. |
体内活性 | DRF-1042 treatment displays poor myelosuppression, in clonogenic assay against murine, canine, and human bone marrow cells. Which supports the possibility of protracted dose schedule in both experimental and clinical studies [2]. |
分子量 | 408.4 |
分子式 | C22H20N2O6 |
CAS No. | 200619-13-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (122.43 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.4486 mL | 12.2429 mL | 24.4858 mL | 61.2145 mL |
5 mM | 0.4897 mL | 2.4486 mL | 4.8972 mL | 12.2429 mL | |
10 mM | 0.2449 mL | 1.2243 mL | 2.4486 mL | 6.1214 mL | |
20 mM | 0.1224 mL | 0.6121 mL | 1.2243 mL | 3.0607 mL | |
50 mM | 0.049 mL | 0.2449 mL | 0.4897 mL | 1.2243 mL | |
100 mM | 0.0245 mL | 0.1224 mL | 0.2449 mL | 0.6121 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
DRF-1042 200619-13-2 Others DRF 1042 DRF1042 Inhibitor inhibitor inhibit