85
12
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1889 |
MCL0020
MCL 0020 |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
MCL0020 是一种有效的选择性黑素皮质素MC4受体拮抗剂,IC50为 11.63 nM。它剂量依赖性减轻束缚应激诱发的厌食症,在体内表现出抗焦虑样活性。 | |||
T14898 |
CCG-63808
|
GTPase | GPCR/G Protein |
CCG-63808 是一种有效的、可逆的G 蛋白信号调节子抑制剂。 | |||
T74794 |
USP28-IN-4
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
USP28-IN-4 是一种高效的 USP28 抑制剂,对 USP28 的 IC50 值为 0.04 μM。USP28-IN-4 具有抗癌活性,抑制 USP2、USP7、USP8、USP9x、UCHL3和UCHL5。USP28-IN-4 对人结直肠癌和肺鳞癌细胞具有细胞毒性,通过泛素-蛋白酶体系统对c-Myc的细胞水平进行剂量依赖性下调。 | |||
T68162 |
Tiflucarbine
Tiflucarbina |
5-HT Receptor; PDE | GPCR/G Protein; Metabolism; Neuroscience |
Tiflucarbine 是一种潜在的非选择性5-HT激动剂,具有抗抑郁活性。Tiflucarbine 剂量依赖性的增加了大鼠脑中可溶性钙调蛋白(CaM)依赖性磷酸二酯酶的比活性。 | |||
T60008 |
BCL6-IN-6
|
BCL | Apoptosis |
BCL6-IN-6 是 Bcl-6 的抑制剂,可用于关于弥漫性大 B 细胞淋巴瘤的研究。 BCL6-IN-6 阻断 Bcl-6 与其辅阻遏物的相互作用,并以剂量依赖性方式重新激活 Bcl-6 靶基因。 | |||
TP1858L |
Phe-Met-Arg-Phe, amide acetate
Phe-Met-Arg-Phe, amide acetate(64190-70-1 freebase) |
Potassium Channel | Membrane transporter/Ion channel |
Phe-Met-Arg-Phe, amide acetate(64190-70-1 freebase) 剂量依赖性 (ED50=23 nM) 激活肽能尾背神经元中的 K+ 电流。这种肽似乎在大脑的某些区域与神经肽 Y 一起定位。 | |||
T4012 |
UNC926
UNC-926,UNC 926 hydrochloride |
Epigenetic Reader Domain | Chromatin/Epigenetic |
UNC926 (UNC-926) 抑制 L3MBTL1,还对 L3MBTL3 表现出低微摩尔亲和力。它抑制 3xMBT 结构域与 H4K20me1 的结合,可选择性和剂量依赖性地抑制 L3MBTL13xMBT-H4K20me1 相互作用。 | |||
T77729 |
MY-1076
|
Apoptosis; YAP | Apoptosis; Stem Cells |
MY-1076 是一种高效的 YAP 抑制剂,具有抗胃癌活性。MY-1076 剂量依赖性诱导G2/M期阻滞,诱导 YAP 降解和细胞凋亡,抑制微管蛋白聚合。MY-1076 抑制 MGC-803、SGC-7901、HCT-116 和 KYSE450 细胞增殖。 | |||
T16448 | PD173212 | Calcium Channel | Membrane transporter/Ion channel; Metabolism |
PD 173212是一种阻断 N-型电压敏感性钙通道 (N-type voltage sensitive calcium channel, Cav2.2)的阻滞剂。PD173212的腹腔注射给药(0.0017-1.7 μmol/kg)显著降低了2,4-二硝基苯磺酸(DNBS)诱导结肠炎小鼠的内脏超敏反应。 | |||
T72057 | H1k | CDK | Cell Cycle/Checkpoint |
H1k 是一种 eudistomin Y 荧光衍生物和溶酶体靶向抗增殖剂。它可以剂量依赖性地增加自噬信号,下调细胞周期蛋白依赖性激酶(cyclin-dependent kinase, CDK1)和细胞周期蛋白 B1的表达。 | |||
T4062 |
CAY10602
|
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
CAY10602 是一种SIRT1激活剂,可剂量依赖性地抑制 THP-1 细胞中脂多糖对 TNF-α 的 NF-κB 依赖性诱导。 | |||
T14346 |
Aumitin
|
Others; Autophagy | Autophagy; Others |
Aumitin 是一种基于二氨基嘧啶的自噬抑制剂,以剂量依赖性抑制饥饿和雷帕霉素诱导的自噬,IC50分别为 0.12 μM 和 0.24 μM。它通过靶向复合物 I 抑制线粒体呼吸。 | |||
T9214 |
ELOVL6-IN-1
|
Others | Others |
ELOVL6-IN-1 是一种选择性 ELOVL6抑制剂,口服具有活性。它对丙二酰辅酶 a (Ki:994 nM) 和对棕榈酰辅酶 a 具有非竞争性抑制 ELOVL6 作用。它能够剂量依赖性的一种小鼠 ELOVL6(IC50:0.350 μM)。 | |||
TQ0159 |
U-73343
U 73343 |
Phospholipase | Metabolism |
U-73343 是一种 U-73122 的无活性类似物,能够剂量依赖性的抑制酸分泌,可作为 U-73122 的阴性对照。其中 U 73122 是一种有效的磷脂酶 C (phospholipase C) 和 5-脂氧合酶 (5-LO (5-lipoxygenase)) 抑制剂,对磷脂酶 C 的 IC50值约为 1-2.1 µM。 | |||
T11368 |
GATA4-NKX2-5-IN-1
|
Others | Others |
GATA4-NKX2-5-IN-1 剂量依赖性地抑制 GATA4–NKX2-5转录协同作用(IC50:3 μM),但不影响参与调节 GATA4 磷酸化的蛋白激酶的活性。它能够调节肥大激动剂诱导的心脏基因表达。 | |||
T3536 |
AZD1283
|
P2Y Receptor | GPCR/G Protein; Neuroscience |
AZD1283是P2Y12受体拮抗剂,EC50为3.0 ug/kg/min,结合的IC50为11 nM。它剂量依赖性地诱导血流量增加和抑制 ADP 诱导的血小板聚集,抗血栓形成的 ED50 值分别为 3.0 和 10 μg/kg/min。 | |||
T67956 |
Litoxetine
|
5-HT Receptor | GPCR/G Protein; Neuroscience |
Litoxetine 是一种选择性的5-HT 摄取抑制剂,是具有5-HT3受体拮抗剂。Litoxetine 可作为一种抗抑郁剂,在雪貂身上显示出止吐特性。Litoxetine (1和10毫克/公斤静脉注射)剂量依赖性地减少了反胃和呕吐的次数,延迟了呕吐的发生。Litoxetine 对大脑5HT3受体有亲和力(Ki = 85 nM)。 | |||
T62238 |
AMPK activator 4
|
AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
AMPK activator 4 是一种有效且具有选择性的AMPK激活剂,不抑制线粒体复合物 I。AMPK activator 4 选择性地激活肌肉组织中的 AMPK且剂量依赖性地改善正常小鼠的糖耐量,显著降低 db/db 糖尿病小鼠的空腹血糖水平和改善胰岛素抵抗。AMPK activator 4 具有降血糖作用。 | |||
T15368L |
Galantide acetate
Galantide acetate(138579-66-5 Free base) |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Galantide acetate 是一种特殊的甘丙肽受体 (galanin receptor) 拮抗剂,是一种由甘丙肽和 P 物质片段组成的肽段,在大鼠下丘脑可识别两类甘丙肽结合位点 (KD 分别小于 0.1 nM 和 ~6 nM)。Galantide 剂量依赖性 (IC50=1.0 nM) 拮抗甘丙肽介导的葡萄糖诱导的小鼠胰岛胰岛素分泌抑制。Galantide acetate 似乎与单一的 SP 受体群结合 (KD~40 nM)。 | |||
TP1369L |
[Sar9,Met(O2)11]-Substance P acetate
[Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base) |
Neurokinin receptor | GPCR/G Protein; Neuroscience |
[Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base) 是一种速激肽 NK1 受体选择性激动剂。它是一种选择性速激肽 NK1 受体激动剂。它和 septide(每只大鼠 10-100 pmol,i.c.v.)在增加平均动脉血压 (MAP) 和心率 (HR),但它们的时间进程不同。两种激动剂都以剂量依赖性方式增加洗脸和吸鼻,而它是一种产生美容效果的化合物。 | |||
T74793 |
USP28-IN-3
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
USP28-IN-3是一种高选择性 USP28 抑制剂,对USP28的IC50 值为 0.1 μM。USP28-IN-3 具有抗癌活性,抑制 USP2、USP7、USP8、USP9x、UCHL3和UCHL5。USP28-IN-3 对人结直肠癌和肺鳞癌细胞具有细胞毒性,通过泛素-蛋白酶体系统对c-Myc的细胞水平进行剂量依赖性下调。 | |||
T36126 |
TMP-153
|
||
Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues. ACAT inhibitors improve plasma lipid profile and ameliorate proteinuria in nephrotic animals. TMP-153 is a quinolyl derivative that inhibits ACAT with IC50 values of 5-10 nM in various animals. At 0.5-1.5 mg/kg, TMP-153 dose-dependently reduc... | |||
T3148 |
MK-571 sodium
L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid |
Leukotriene Receptor; LTR | GPCR/G Protein; Immunology/Inflammation |
MK-571 sodium (L-660711 sodium salt) 是一种可口服的选择性白三烯 D4受体拮抗剂,在豚鼠和人肺膜的 Ki 分别为0.22 和 2.1 nM。 | |||
T24554 |
NSC-658497
NSC658497 |
||
NSC-658497 is a SOS1-Ras interaction inhibitor that acts by dose-dependently inhibiting SOS1 GEF activity. | |||
T37816 |
SB 243213
|
||
SB 243213 is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor. SB 243213 shows greater than a 100-fold selectivity over a wide range of neurotransmitter receptors, enzymes and ion channels. SB 243213 has improved anxiolytic profile and has the potential for schizophrenia and motor disorders[1]. SB 243213 shows little affinity (pKi<6) for cloned human 5-HT1A, 5-HT1B, 5-HT1E, 5- HT1F and 5-HT7 receptors. It shows... | |||
T70944 | Carotegrast methyl HCl | ||
Carotegrast methyl, also known as AJM300 and PTC-100, is an orally-active small molecule that antagonises the α4 integrin receptor. AJM300 reduces inflammation by blocking leucocyte trafficking. Oral treatment with AJM300 dose-dependently inhibited lymphocyte homing to Peyer's patches and increased the peripheral lymphocyte count in the same dose range. AJM300 dose-dependently prevented the development of experimental colitis in mice. | |||
T68782 |
Ono 11006
|
||
Ono 11006 is a thromboxane agonist that dose dependently reduced the positive inotropic effect induced by field stimulation. | |||
T70993 |
WO-459
|
||
WO-459 is a novel GPR52 agonist, dose-dependently inducing elevation of intracellular cAMP in HEK293/GPR52 cells. | |||
T29223 |
ZK110841
ZK-110841,ZK 110841 |
||
ZK110841 is an agonist of prostaglandin DP-receptors on human platelet. ZK110841 elevated the cyclic AMP level in EBTr cells dose-dependently, being more than 100 fold over the basal level at 1 microM. | |||
T71601 | CU-2010 | ||
CU-2010 is a synthetic serine protease inhibitor with antifibrinolytic and anticoagulant properties. CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a canine model. | |||
T68934 | VT101 free base | ||
VT101 is a TEAD Auto-palmitoylation inhibitor that Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT101 inhibited the firefly luciferase reporter dose-dependently and had no 204 effect on the Renilla luciferase reporter. | |||
T71364 | Selatogrel | ||
Selatogrel, also known as ACT-246475, is a reversible, selective, and potent antagonist of the platelet P2Y12 receptor. It therefore acts as a platelet aggregation inhibitor. Selatogrel dose-dependently blocks thrombus formation and displays a wide therapeutic window. | |||
TP2072 |
BeKm-1
|
||
Potent and selective KV11.1 (hERG) channel blocker. Selective for KV11.1 over a panel of 14 other potassium channels. Dose-dependently prolongs QTc interval in isolated rabbit heart. | |||
T27772 |
L-736380
L-736,380,L 736380,L736,380,L 736,380 |
||
L-736380 is a CCK-B receptor antagonist. L-736,380 dose-dependently inhibited gastric acid secretion in anesthetized rats (ID(50), 0.064 mg/kg) and ex vivo binding of [(125)I]CCK-8S in BKTO mice brain membranes (ED(50), 1.7 mg/kg). | |||
T75953 |
BeKm-1 TFA
|
||
BeKm-1 TFA is a potent, selective blocker of the KV11.1 (hERG) channel, demonstrating specificity for KV11.1 over 14 other potassium channels. This compound dose-dependently prolongs the QTc interval in isolated rabbit hearts, affirming its role as a selective inhibitor. | |||
T71424 | VT-102 free base | ||
VT-102 is a TEAD Auto-palmitoylation inhibitor that Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT102 inhibited the firefly luciferase reporter dose-dependently and had no 204 effect on the Renilla luciferase reporter. | |||
T64279 | ODN 21158 | ||
ODN 21158 是一种 G 修饰的 TLR3 和 TLR9 的有效抑制剂,无细胞毒性。ODN 21158 能够剂量依赖性地抑制 IFN-α 分泌。 | |||
T36198 |
Avenanthramide-C methyl ester
|
||
Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells. | |||
TP1858 |
Phe-Met-Arg-Phe, amide
|
||
Phe-Met-Arg-Phe, amide dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons. This peptide appears to localize with neuropeptide Y in some regions of the brain. | |||
T35818 |
CAY10669
|
||
CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid . At 30-60 μM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro. | |||
T25934 |
Pentisomide
Pentisomidum |
||
Pentisomide 是一种抗心律失常的化合物,对去极化(Ia 和 Ic 类作用)和复极有显著作用。它可剂量依赖性地抑制缺血再灌注心律失常。Pentisomide 已进入治疗心律失常的 II 期临床试验。 | |||
T71082 |
DW532
|
||
DW532 is one of simplified analogues of hematoxylin that has shown broad-spectrum inhibition on tyrosine kinases and in vitro anti-cancer activities. DW532 inhibited EGFR and VEGFR2 in vitro kinase activity (the IC50 values were 4.9 and 5.5 μmol/L, respectively), and suppressed their downstream signaling. DW532 dose-dependently inhibited tubulin polymerization via direct binding to tubulin, thus disrupting the mitotic spindle assembly and leading to abnormal cell division. In a panel of human ca... | |||
T64302 | XIAP/cIAP1 antagonist-1 | ||
XIAP/cIAP1 antagonist-1 是一种有效的、口服具有活力的 XIAP/cIAP1 拮抗剂,能够作用于 XIAP (EC50: 5.1 nM) 和 cIAP1 (EC50: 0.32 nM)。XIAP/cIAP1 antagonist-1 能够剂量依赖性地抑制体内肿瘤生长。 | |||
T35467 |
(±)18-HETE
|
||
(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has negligible effects on ATPase activity. 18(R)-HETE at 1 μM completely blocks 20-HETE-induced vasoconstriction of renal arterioles. | |||
T62408 | PI3Kδ-IN-11 | ||
PI3Kδ-IN-11 是一种高效的、选择性的 PI3Kδ 抑制剂 (IC50: 27.5 nM),能够剂量依赖性地阻断 PI3K/Akt 通路的活性。PI3Kδ-IN-11 能够用于 B 细胞或 T 细胞相关的恶性肿瘤研究。 | |||
T80704 |
α-Pompilidotoxin
α-PMTX |
||
α-Pompilidotoxin (α-PMTX) 是从 Anoplius samariensis 的毒液中分离的一种神经毒素。它能剂量依赖性地增强兴奋性突触后电流(EPSCs),并且这种增强作用是可逆的。α-Pompilidotoxin 在神经科学研究中被作为实验工具广泛应用。 | |||
T80882 |
Val-Gly-Ser-Glu
NSC 350591 |
||
Val-Gly-Ser-Glu (NSC 350591) 是一种ECF-A四肽。该化合物能剂量依赖性地提升人类嗜酸性粒细胞的数量,而不影响中性粒细胞的数量,并可与补体包被的绵羊红细胞(EAC3b)形成玫瑰花结。 | |||
T81713 | N-4′-(p-Trifluoromethylphenyl)butyl-DAB | ||
N-4′-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) 作为溶酶体酸 α-葡萄糖苷酶 (GAA) 的激动剂,在携带 M519V 突变的 Pompe 病患者成纤维细胞中,能剂量依赖性地提升细胞内 GAA 的活性。 | |||
T71088 | AM-211 sodium | ||
AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it shows selectivity over other prostanoid receptors and enzymes. AM211 exhibits good oral bioavailability in rats and dogs and dose-dependently inhibits 13,14-dihydro-15-keto-PGD(2)-induced leukocytosis in a guinea pig pharmacodynamic assay. | |||
T75915 |
CTOP TFA
|
||
CTOP TFA为高效、高选择性μ-阿片受体(μ-opioid receptor)拮抗剂。其能拮抗吗啡引发的急性镇痛效果及运动能力增强,同时升高伏隔核外多巴胺水平,并呈剂量依赖性增强运动能力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2S1396 |
3-O-Acetyloleanolic acid
齐墩果酸3-乙酸酯,齐墩果酸 3-乙酸酯 |
Apoptosis | Apoptosis |
3-O-Acetyloleanolic acid 是从 Vigna sinensisK. 种子中提取得到的一种齐墩果醇酸,可诱导癌细胞凋亡并拥有抗血管生成作用。 | |||
TN1600 |
Eclalbasaponin I
|
Others | Others |
Eclalbasaponin I 分离自鳢肠中,具有抗肿瘤作用,能够抑制肝癌细胞 smmc-7721 的增殖(IC50:111.1703 μg/ml)。 | |||
T4S0795 |
Berberrubine chloride
9-Berberoline Chloride,Beroline,Beroline Chloride,小檗红碱,Berberrubine,9-Berberoline |
IL Receptor | Immunology/Inflammation |
Berberrubine chloride (9-Berberoline Chloride) 是一种黄连素的有效代谢物,能够改善动物模型中溃疡性结肠炎的症状。 | |||
T3926 |
Echinatin
刺甘草查尔酮,Retrochalcone |
Free radical scavengers | oxidation-reduction |
Echinatin (Retrochalcone) 是分离自中草药甘草中,具有保肝和抗炎活性。在大鼠中,它可以被快速吸收和消除,并广泛分布,绝对生物利用度约为 6.81%。 | |||
T2973 |
Astragaloside IV
AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV |
MMP; ERK; Estrogen/progestogen Receptor; JNK | Endocrinology/Hormones; MAPK; Proteases/Proteasome |
Astragaloside IV (AS-IV) 是从黄芪中分离得到的一种皂苷,抑制ERK1/2和JNK 激活,在乳腺癌细胞 MDA-MB-231 中,下调(MMP)-2和(MMP)-9的信号通路。 | |||
TN2228 |
Soyasaponin Aa
大豆皂苷 AA,大豆皂苷Aa |
PPAR | DNA Damage/DNA Repair; Metabolism |
Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα± in 3T3-L1 adipo | |||
TN6645 | Lucidumol A | ||
Lucidumol A has relatively good effect against aldose reductase with IC50 of 19.1uM. Lucidumol A has cytotoxic activity, it reduced cell growth in three human carcinoma cells (Caco-2, HepG2, and HeLa cells) dose dependently with LC50s from 20.87 to 84.36 | |||
TN1806 |
Isotetrandrine
|
IL Receptor; NF-κB; MAPK | Immunology/Inflammation; MAPK; NF-κB |
Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue | |||
TN5248 |
Voleneol
|
NOS; COX; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependently suppress the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenas | |||
TN5474 |
Bonducellin
|
||
Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bonducellin shows weak antimalarial ac | |||
T36961 |
Malformin C
|
||
Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates colchicine-induced M phase arrest in Jurkat cells (IC50 = 24 nM). Malformin C inhibits cell growth dose-dependently in Colon 38 and HCT 115 cancer cells (IC50s = 0.27 and 0.18 μM, respectively) but ... | |||
T36417 |
Nargenicin
Antibiotic 47444 |
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Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg/ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg/mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (... |