167
5
1
1
105
Cat. No. | Product Name | ||
---|---|---|---|
DO1200 | 药物靶点库 | 53200 compounds | |
数量多,含53200种小分子化合物,是高通量筛选的有力工具; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0136 |
ATM/ATR inhibitor kit
ATM/ATR inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10630 |
BuChE-IN-TM-10
TM-10 |
AChR | Neuroscience |
BuChE-IN-TM-10 (TM-10) 是一种有效的丁基胆碱酯酶 (BuChE) 抑制剂,其IC50 值为8.9 nM。BuChE inhibitor 1能够抑制和分解自诱导的Aβ聚合, 表现出强大的抗氧化活性和良好的血脑屏障 (BBB) 渗透性。可用于阿尔兹海默症的研究。 | |||
T17103 |
TM-N1324
|
Others; GHSR | GPCR/G Protein; Others |
TM-N1324 是一种 GPR39 激动剂。 TM-N1324 在没有和存在 Zn2+ 的情况下分别以 280 nM 和 9 nM 的高效率和效力激活人 GPR39。 TM-N1324 对鼠 GPR39 表现出相似的效力,EC50 分别为 180 nM 和 5 nM。 | |||
T13169 |
TM-25659
|
Others | Others |
TM-25659是一种具有 PDZ 结合图案的转录协同激活剂(TAZ)的调节剂,具有抗骨质疏松和抗肥胖的活性。 | |||
T11120 |
Duocarmycin TM
|
DNA Alkylation; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Duocarmycin TM 是一种有抗肿瘤活性的抗生素,也是一种 DNA 烷化剂。 | |||
T17105 |
TM6089
|
HIF/HIF Prolyl-Hydroxylase | Chromatin/Epigenetic; Metabolism |
TM6089 是一种脯氨酰羟化酶抑制剂,可在没有铁螯合的情况下刺激 HIF 活性,诱导血管生成,并保护器官免受缺血。 | |||
T24890 |
TM-233
TM 233 |
||
TM-233 is an inhibitor of both JAK/STAT and proteasome activities that acts by inducing cell death in myeloma cells. | |||
T8962 |
TM5007
|
PAI-1 | Metabolism |
TM5007 是纤溶酶原激活物抑制剂-1(PAI-1;IC50 为 29 uM)的强效抑制剂。 | |||
T8511 |
TM38837
|
Cannabinoid Receptor | GPCR/G Protein |
TM38837 是外周选择性大麻素受体1型受体拮抗剂。它减少精神病副作用的倾向。它对大脑的渗透率有限,以降低或防止 CNS 不良反应,并保留潜在的抗肥胖作用。 | |||
T4254 |
TM5441
|
PAI-1; Apoptosis | Apoptosis; Metabolism |
TM5441 是口服生物可利用的纤溶酶原激活物抑制剂-1 抑制剂,抑制多个癌症细胞系的 IC50值在 13.9 到 51.1 μM。它诱导几种人类癌症细胞的内在调亡,减弱 Nω-硝基-1-精氨酸甲酯诱导的心脏高血压和血管衰老。 | |||
T4255 |
TM5275 sodium
TM5275 sodium salt |
PAI-1 | Metabolism |
TM5275 sodium (TM5275 sodium salt) 是一种纤溶酶原激活物抑制剂,IC50=6.95 μM。 | |||
T69872 |
TM-9
|
||
TM-9 is a novel multi-function inhibitor for the treatment of Alzheimer's disease (AD). TM-9 exhibits potent and balanced inhibitory activities against ChE and MAO-B. | |||
T0245 |
RS 61443
RS61443,吗替麦考酚酯,Mycophenolate mofetil,TM-MMF |
Dehydrogenase | Metabolism |
RS 61443 (Mycophenolate mofetil) 是一种免疫抑制剂,一种非竞争性、选择性和可逆的肌苷一磷酸脱氢酶 (IMPDH) 抑制剂。 | |||
T12875 | Seco-Duocarmycin TM | Others | Others |
Seco-Duocarmycin TM is an agent of DNA alkylator belonging to Duocarmycins family that inhibits DNA synthesis. It used as the cytotoxic component in antibody-drug conjugates (ADC). | |||
T23644 |
Advastab TM 188
Mark OTM,Mellite 831C,Jingxi 8831 |
||
Advastab TM 188 is organometallic. It also works as an anticancer drug. | |||
T17982 |
Fmoc-Val-Cit-PAB-Duocarmycin TM
|
Others | Others |
Fmoc-Val-Cit-PAB-Duocarmycin TM is a drug-linker conjugate designed for antibody-drug conjugation (ADC), utilizing the antitumor antibiotic Duocarmycin TM. It is connected through the linker Fmoc-Val-Cit-PAB. | |||
T26281 |
TM6008
TM 6008,TM-6008 |
||
TM6008 is an inhibitor of prolyl hydroxylase that protects against cell death after hypoxia. | |||
T25689 |
Leuseramycin
TM 531,TM531,Antibiotic TM-531,TM-531 |
||
Leuseramycin is a polyether antibiotic isolated from Streptomyces hygroscopicus TM-531. | |||
T34892 |
TM608
TM-608,TM 608 |
||
TM608 is a potent selective c-Met inhibitor that targets mitochondria and kills erlotinib-resistant lung cancer cells, rapidly accumulates in mitochondria, and inhibits MET activation in high MET expression, erlotinib-resistant HCC827B cells (total cell l | |||
T63012 | TM-1 | ||
TM-1 是一种强效的丙酮酸脱氢酶激酶 (PDHK) 抑制剂,能够抑制 PDHK1 (IC50: 2.97 μM) 和 PDHK2 (IC50: 5.2 μM)的活性。TM-1 可以阻断丙酮酸脱氢酶复合物 (PDHC) 磷酸化,并抑制癌细胞增殖。 | |||
T20649 |
Lauryl trisiloxane
Tm-121,Tm 121,Dodecylheptamethyltrisiloxide,Tm121 |
||
Lauryl trisiloxane is a surfactant. | |||
T23839 |
Buquinolate
Buchinolatum,Butoril,Bukhinolyat,Bonaid TM,丁喹酯 |
Others | Others |
Buquinolate (Bonaid TM) 是一种用于家禽的抗球虫剂,用药后的鸡可以产生更高水平的产蛋量和体重增加。它不会干扰对球虫的免疫力的形成。 | |||
T67250 | SingaCycle(TM)-A1 | ||
SingaCycle(TM)-A1 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67250。 | |||
T9004 |
TM2-115
|
Parasite | Microbiology/Virology |
TM2-115 是疟原虫组蛋白甲基转移酶的抑制剂,可导致疟原虫快速且不可逆的死亡。 | |||
T7359 |
CAY10471 Racemate
TM30089 Racemate,3-[[(4-氟苯基)磺酰基]甲基氨基]-1,2,3,4-四氢-9H-咔唑-9-乙酸 |
GPR; Prostaglandin Receptor | Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation |
CAY10471 Racemate (TM30089 Racemate) 是一种高选择性的 CRTH2/DP 2 受体拮抗剂,对 hCRTH2 的Ki 值为 0.6 nM,对其选择性远高于人血栓素 A2 受体 TP 或 PGD2 受体 DP。它对大小鼠的同源 CRTH2 也具有拮抗作用。 | |||
T69871 |
ICRF-196
|
||
ICRF-196 is a Topoisomerase II Inhibitor and antineoplastic agent. | |||
T83951 |
TM2 TEAD inhibitor
|
||
TM2 TEAD抑制剂是一种有效并且可逆的TEA领域转录因子抑制剂(IC50为TEAD4自动棕榈酰化和TEAD2棕榈酰化分别为38 nM和156 nM)。它抑制TEAD-YAP的结合和转录活性。TM2 TEAD抑制剂在YAP依赖型癌症细胞中,无论是单独使用还是与MEK抑制剂联合使用,都显示出强大的抗增殖效果。同时抑制体外YAP依赖的肝脏类器官生长。 | |||
T19071 |
TMB
BM blue,3,3',5,5'-四甲基联苯胺,Sure Blue TMB |
Others | Others |
TMB (BM blue) 是一种免疫组化及 ELISA 的显色底物。 | |||
T6283 |
Wortmannin
SL-2052,渥曼青霉素,KY-12420 |
ATM/ATR; DNA-PK; Serine/threonin kinase; PLK; PI3K; Antibiotic; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling |
Wortmannin (SL-2052) 是一种 PI3K 抑制剂 (IC50=3 nM),具有共价性和不可逆性。Wortmannin 也是一种 PlK1 和 PlK3 的抑制剂 (IC50=5.8/48 nM),可以阻断自噬。 | |||
T22842 |
HTMT dimaleate
HTMT马来酸氢盐,Histamine Trifluoromethyl Toluidide Dimaleate |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) 是一种 H1 和 H2 受体激动剂。在自然抑制细胞中,它在 H2 受体介导的效应中的活性是组胺的 4 x 104倍。 | |||
T12882L |
Setmelanotide Acetate(920014-72-8 free base)
RM-493 Acetate,IRC-022493 Acetate,BIM-22493 Acetate |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) 是黑皮质素 4 受体 (MC4R) 的选择性激动剂(人和大鼠 MC4R,EC50 分别为 0.27 nM 和 0.28 nM)。 | |||
T7109 |
TMB-PS
TMBZ-PS |
Others | Others |
TMB-PS (TMBZ-PS) 是 N-(3-sulfopropyl)-3,3',5,5'-tetramenthylbenzidine sodium salt,具有水溶性,可适应各种 ph 环境。 | |||
T10395L |
ATM-3507
|
Others | Others |
ATM-3507 is an inhibitor of tropomyosin. In human melanoma cell lines, the IC50s are from 3.83-6.84 μM. | |||
T83630 |
STM3006
|
Others | Others |
STM3006 是一种具有口服活性、选择性和和高效性的 METTL3 抑制剂,具有抗肿瘤活性,可用于研究急性髓系白血病(AML)。 | |||
T9603 |
MNITMT
|
||
MNITMT 是一种有效的免疫抑制剂 (immunosuppressive agent),没有骨髓毒性。 | |||
T60080 |
TMPH
2,2,6,6-Tetramethylpiperidin-4-yl heptanoate |
AChR | Neuroscience |
TMPH 是一种 nAChR 抑制剂,可抑制缺乏 α5、α6 或 β3 亚基的 nAChR。 TMPH 可用于关于 nAChR 功能障碍或神经系统疾病的研究。 | |||
T7292 |
FITM
4-氟-N-[4-[6-(异丙基氨基)嘧啶-4-基]-1,3-噻唑-2-基]-N-甲基苯甲酰胺 |
GluR | Neuroscience |
FITM 是mGlu1受体的一种负变构调节剂,Ki 值为2.5 nM。 | |||
T9249 |
ITMN4077
|
Antiviral | Immunology/Inflammation |
ITMN4077 对感染人类 HuH7 细胞的丙型肝炎病毒具有抗病毒活性,评估为抑制 HCV 亚基因组复制子复制,EC50 为 2.131μM。 | |||
T21537L |
TMC647055 Choline Hydroxide Salt
TMC647055 Choline Hydroxide Salt (1204416-97-6 free base) |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
TMC647055 Choline Hydroxide Salt 是一种新型有效的 HCV NS5B 聚合酶非核苷抑制剂,可用于治疗 HCV 感染。它具有纳摩尔级细胞效力(EC(50) 为 82 nM),相关细胞毒性较小(CC(50)>20 μM),在大鼠和狗中具有良好的药代动力学特征。 TMC647055 显示出有体外生化、动力学和病毒学特征的前景。 | |||
T8902 |
DOTMA
Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium |
Others | Others |
DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) 作为 tetra-methylated DOTA 类似物,是一种阳离子脂类,被用作基因治疗的非病毒载体。它已被用作脂质体的成分,可用于封装 siRNA、microRNA 和寡核苷酸,并用于体外基因转染。在体外和体内均表现出良好的基因转染效果。DOTMA 诱导脂质体上的正电荷,从而促进脂质体与细胞膜的有效相互作用。 | |||
T17107 |
TMC353121
|
Others | Others |
TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9). | |||
T1857 |
TMP269
|
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
TMP269 是一种有效的特异性 IIa 类 HDAC 抑制剂,分别抑制 HDAC 4/HDAC 5/HDAC 7/HDAC 9,IC50值分别为 157 nM,97 nM,43 nM 和 23 nM。 | |||
T13173 |
TMPA
|
Others; AMPK | Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling |
TMPA 是一种核受体 Nur77 和 LKB1 相互作用的拮抗剂。 | |||
T8623 |
TMIFRY8XAG
4,4,-二(4-氟苯)氯丁烷,1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE),4-oxo-1,4-dihydroquinoline-2-carboxylic acid |
Others | Others |
TMIFRY8XAG (4-oxo-1,4-dihydroquinoline-2-carboxylic acid) 是 Zerumbone 的衍生物,对 HeLa 癌细胞具有潜在的抗肿瘤作用。 | |||
T9060 |
STM2457
|
Apoptosis; Others | Apoptosis; Others |
STM2457 是一种 RNA 甲基转移酶 METTL3 的抑制剂 (IC50=16.9 nM),具有选择性和口服活性。STM2457 可用于急性髓系白血病 (AML) 的研究。 | |||
T19072 |
TMRE
四甲基若丹明乙酯酸铵,Tetramethylrhodamine ethyl ester perchlorate |
Others | Others |
TMRE (Tetramethylrhodamine ethyl ester perchlorate) 是线粒体特异性染料 (λex=550 nm,λem=575 nm)。 | |||
T13174 |
TMPyP4 tosylate
TMP 1363 |
DNA/RNA Synthesis; Telomerase | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
TMPyP4 tosylate (TMP 1363) 是四链体 (G-quadruplex) 的特异性配体,抑制四链体和 IGF-1 之间的相互作用。它也是端粒酶抑制剂,在骨肉瘤细胞系中显示抗肿瘤作用。 | |||
T19068 |
TMA-DPH
|
Others | Others |
TMA-DPH 是疏水性荧光膜探针 (Ex=355 nm; Em=430 nm)。 | |||
T78188 |
STM2120
|
Others | Others |
STM2120 是一种有效的 METTL3 抑制剂(IC50:64.5 μM),对 METTL14 具有抑制作用。 | |||
T3585 |
TMS
(E)-2,3',4,5'-tetramethoxystilbene,2,3',4,5'-Tetramethoxystilbene |
P450 | Metabolism |
TMS (2,3',4,5'-Tetramethoxystilbene) 是一种白藜芦醇的甲基化衍生物,也是具有选择性的CYP1B1竞争性抑制剂,其IC50=6 nM,Ki=3 nM。它对 CYP1A1 (IC50:300 nM) 及 CYP1A2 (IC50:3.1 μM) 的抑制作用较小。它具有抗癌作用。 | |||
T40732 |
TMPD dihydrochloride
|
||
TMPD dihydrochloride 是酶促转化氧化还原的活性底物和用于还原血红素过氧化物酶的电子供体。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6293 |
Mycophenolate Mofetil
TM-MMF,吗替麦考酚酯,RS 61443 |
Apoptosis; Dehydrogenase; Drug Metabolite | Apoptosis; Metabolism |
Mycophenolate Mofetil (TM-MMF) 是 Mycophenolic acid 的吗啉乙酯前药。它通过抑制肌苷一磷酸脱氢酶抑制从头嘌呤合成,显示出选择性淋巴细胞抗增殖作用。 | |||
T7892 |
ATMP
|
Others | Others |
ATMP 是一种具有螯合特性的膦酸。它是一种阻垢剂。 | |||
T73815 |
TMC-205
|
||
TMC-205,一种具抗肿瘤细胞增殖活性的天然真菌代谢产物,为SV40启动子的转录上调因子。 | |||
TN6459 |
Betmidin
|
||
Betmidin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6459,CAS号为 35589-22-1。 | |||
T75670 |
Lacto-N-fucopentaose II
|
||
Lacto-N-fucopentaose II (LNFP II)作为人Lewis血型决定因子的半抗原,其单唾液神经节苷/糖脂以及唾液酰衍生物CA 19-9,都是胆胰恶性肿瘤中的分子肿瘤标记物(TM)。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06076 |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like receptor... |
Human | HEK293 Cells |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1. | |||
TMPY-00414 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)
ILT-11,CD85F,LIR-9,LIR9,LILRB7,CD85,ILT11,leukocyte immunogl... |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1. | |||
TMPJ-00857 |
Thrombomodulin Protein, Mouse, Recombinant (His)
Fetomodulin,Thbd,BDCA-3,Thrombomodulin,CD141,TM |
Mouse | HEK293 Cells |
Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits ... | |||
TMPY-05829 |
Thrombomodulin Protein, Human, Recombinant (His)
thrombomodulin,THPH12,CD141,TM,AHUS6,BDCA3,THRM |
Human | HEK293 Cells |
Thrombomodulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.54 kDa and the accession number is P07204. | |||
TMPY-03069 |
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (His)
leukocyte immunoglobulin-like receptor, subfamily A (with |
Rat | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession number is D4A6Y0. | |||
TMPY-03097 |
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (hFc)
leukocyte immunoglobulin-like receptor, subfamily A (with |
Rat | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.8 kDa and the accession number is D4A6Y0. | |||
TMPY-01843 |
SEMA6A Protein, Human, Recombinant (His)
HT018,VIA,sema domain, transmembrane domain (TM), a... |
Human | HEK293 Cells |
SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SEMA6A may be a potential prognostic biomarker in the treatment of GBM. Among different semaphorins tested by reverse transcriptase-polymerase chain reaction in human immune cells, the expression of class 6 transmembrane semaphorin SEMA6A was restricted to dendritic cells (DCs). | |||
TMPY-06147 |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His)
ILT1,LIR7,LIR-7,leukocyte immunoglobulin-like receptor, subf... |
Human | HEK293 Cells |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.4 kDa and the accession number is Q8N149-1. | |||
TMPY-05230 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His), Biotinylated
CD85,ILT11,LIR9,ILT-11,CD85F,LIR-9,leukocyte immunoglobulin-... |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1. | |||
TMPY-05605 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi), Biotinylated
leukocyte immunoglobulin-like receptor, subfamily A (with |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.5 kDa and the accession number is A6NI73-1. | |||
TMPY-04309 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc)
LILRB7,LIR9,leukocyte immunoglobulin-like receptor, subfamil... |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is A6NI73-1. | |||
TMPK-00865 |
TM4SF1 Protein-VLP, Human, Recombinant
TAAL6,L6,H-L6,M3S1 |
Human | HEK293 Cells |
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis. | |||
TMPY-00059 |
TM2D1 Protein, Human, Recombinant (mFc)
TM2 domain containing 1,BBP |
Human | HEK293 Cells |
TM2D1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 35.1 kDa and the accession number is Q9BX74. | |||
TMPY-03871 |
TM4SF2/TSPAN7 Protein, Mouse, Recombinant (His)
AI323365,Tm4sf2,PE31,A15,R74651,TALLA,Mxs1,Cd231,12... |
Mouse | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPY-03930 |
TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (mFc)
tetraspanin 7 |
Cynomolgus | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPY-03833 |
TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (His)
tetraspanin 7 |
Cynomolgus | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPY-00029 |
TM4SF2/TSPAN7 Protein, Rat, Recombinant (His)
tetraspanin 7 |
Rat | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPY-03862 |
TM4SF2/TSPAN7 Protein, Human, Recombinant (His)
TM4SF2,A15,MXS1,tetraspanin 7,TALLA-1,CCG-B7,CD231,... |
Human | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPY-05586 |
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMIGD2,IGPR-1,transmembrane and immunoglobulin doma... |
Human | HEK293 Cells |
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu... | |||
TMPY-00357 |
HNT/NTM Protein, Human, Recombinant (His)
HNT,NTRI,IGLON2,neurotrimin |
Human | HEK293 Cells |
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3. | |||
TMPH-02251 |
TMOD1 Protein, Human, Recombinant (GST)
|
Human | E. coli |
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. | |||
TMPH-02238 |
TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated
|
Human | E. coli |
TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 90.6 kDa and the accession number is O15393. | |||
TMPH-02728 |
ITM2A Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
ITM2A Protein, Mouse, Recombinant (His) is expressed in in vitro E. coli expression system. | |||
TMPH-02234 |
TMPRSS11A Protein, Human, Recombinant (His)
|
Human | E. coli |
Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. | |||
TMPK-01535 |
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Macropain chain 7,LMP2,Proteasome chain 7,RING12,PSMB9,MHC,R... |
Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPH-03643 |
TmpB Protein, Treponema phagedenis, Recombinant (His & Myc)
|
Treponema phagedenis | E. coli |
Tmp may serve as a porin or transport protein for large molecules. TmpB Protein, Treponema phagedenis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.4 kDa and the accession number is P29720. | |||
TMPH-02945 |
TMPRSS4 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC. TMPRSS4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 57.8 kDa and the accession number is Q8VCA5. | |||
TMPY-04856 |
LRRTM2 Protein, Human, Recombinant (hFc)
leucine rich repeat transmembrane neuronal 2 |
Human | HEK293 Cells |
LRRTM2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is O43300. | |||
TMPH-02235 |
TMPRSS2 Protein, Human, Recombinant (Cell-Free, His)
|
Human | E. coli |
TMPRSS2 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is O15393. | |||
TMPH-02239 |
TMPRSS4 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. TMPRSS4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10... | |||
TMPY-02841 |
Fragilis/IFITM3 Protein, Human, Recombinant (mFc)
DSPA2b,1-8U,interferon induced transmembrane protein 3,IP15 |
Human | HEK293 Cells |
Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon-inducible transmembrane protein family members, IFITM1, 2, and 3, are IEGs required for inhibition of influenza A virus, dengue virus, and West Nile virus replication in vitro. IFITM3 is an IFN-induced anti... | |||
TMPY-02555 |
VSTM1 Protein, Human, Recombinant (His)
SIRL-1,UNQ3033,MGC119161,V-set and transmembrane domain cont... |
Human | HEK293 Cells |
V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds of protein families, including immunoglobulin light and heavy chains, several T-cells such as CD2, CD4, CD80, and CD86, myelin membrane adhesion molecules, junction adhesion molecules (JAM), tyrosine-protein kinase receptors, and the programmed cell death protein1. VSTM1 Protein,... | |||
TMPY-03119 |
TMED1 Protein, Human, Recombinant (His)
Tp24,transmembrane emp24 protein transport domain containing... |
Human | HEK293 Cells |
TMED1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.6 kDa and the accession number is Q13445. | |||
TMPH-03147 |
TMEM168 Protein, Pongo abelii, Recombinant (His & Myc)
|
Pongo abelii | E. coli |
TMEM168 Protein, Pongo abelii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 19.8 kDa and the accession number is Q5RD28. | |||
TMPJ-00438 |
SECTM1A Protein, Mouse, Recombinant (His)
Sectm1a |
Mouse | HEK293 Cells |
SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect h... | |||
TMPH-02202 |
TMSB10 Protein, Human, Recombinant (GST)
|
Human | E. coli |
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. TMSB10 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.6 kDa and the accession number is P63313. | |||
TMPY-03970 |
TMUB2 Protein, Human, Recombinant (His)
transmembrane and ubiquitin-like domain containing 2,TM<... |
Human | HEK293 Cells |
TMUB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q71RG4-2. | |||
TMPH-02233 |
P4HTM Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. | |||
TMPH-02682 |
GSTM3 Protein, Mouse, Recombinant (His & Myc)
|
Mouse | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GSTM3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.0 kDa and the accession number is P19639. | |||
TMPK-01164 |
VSTM5 Protein, Mouse, Recombinant (hFc)
VSTM5,C11orf90 |
Mouse | HEK293 Cells |
V-set and transmembrane domain-containing protein 5 (Vstm5), a cell-adhesion-like molecule belonging to the Ig superfamily, was found in mouse brain. Knock-down of Vstm5 in cultured hippocampal neurons markedly reduced the complexity of dendritic structures, as well as the number of dendritic filopodia. Vstm5 also regulates neuronal morphology by promoting dendritic protrusions that later develop into dendritic spines. VSTM5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cell... | |||
TMPJ-01238 |
VSTM2A Protein, Human, Recombinant (His)
VSTM2,V-set and transmembrane domain-containing pro... |
Human | HEK293 Cells |
VSTM2A, also called VSTM2, is short for V-set and transmembrane domain-containing protein 2A. It is a 236 aa. protein which can be departed into two parts. The first 24 aa. is a signal peptide, and the last is a V-set and transmembrane domain-containing protein 2A. There is a natural variant location which is E84K. | |||
TMPY-04621 |
OSTM1 Protein, Mouse, Recombinant (His)
gl,osteopetrosis associated transmembrane protein 1,HSPC019,... |
Mouse | HEK293 Cells |
OSTM1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.7 kDa and the accession number is Q8BGT0. | |||
TMPH-03558 |
LytM Protein, S. aureus, Recombinant (His)
|
Staphylococcus aureus | E. coli |
Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan. LytM Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is O33599. | |||
TMPY-00148 |
TMED9 Protein, Human, Recombinant (His)
p25,GP25L2,GMP25,HSGP25L2G,transmembrane p24 trafficking pro... |
Human | HEK293 Cells |
TMED9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.8 kDa and the accession number is A0A024R7M0. | |||
TMPY-03365 |
TMEM27 Protein, Human, Recombinant (His)
transmembrane protein 27,NX-17,NX17 |
Human | HEK293 Cells |
TMEM27 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.8 kDa and the accession number is A0A024R127. | |||
TMPY-05440 |
CD28H/TMIGD2 Protein, Human, Recombinant (hFc)
IGPR1,transmembrane and immunoglobulin domain containing 2,I... |
Human | HEK293 Cells |
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu... | |||
TMPY-00068 |
LRRTM4 Protein, Mouse, Recombinant (His)
leucine rich repeat transmembrane neuronal 4,A230052N11,7530... |
Mouse | HEK293 Cells |
LRRTM4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.4 kDa and the accession number is Q80XG9-2. | |||
TMPK-01534 |
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)
RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,MHC,Macropain... |
Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPH-02572 |
TMEM2 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate. | |||
TMPK-01530 |
HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
MHC,LMP-2,PSMB9,LMP2,Macropain chain 7,Proteasome chain 7,RM... |
Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
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