首页工具

登录

搜索结果

Search Results for " t 3 "

225

抑制剂 & 化合物

37

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T24131	HDAC3-IN-T247 HDAC3 inhibitor T247,HDAC3 inhibitor-T247,HDAC3 IN T247,T247	Histone Demethylase; Antiviral	Chromatin/Epigenetic; Immunology/Inflammation
	HDAC3-IN-T247 (HDAC3 inhibitor T247) 是一种具有选择性和有效性的组蛋白去乙酰化酶 3（HDAC3）抑制剂，具有抗癌和抗病毒活性。HDAC3-IN-T247 以剂量依赖的方式诱导人结肠癌 HCT116 细胞中 NF-κB 乙酰化。HDAC3-IN-T247 抑制癌细胞增殖。
T4681	T863 DGAT-3,DGAT-1 inhibitor	Acyltransferase; Transferase	Metabolism
	T863 (DGAT-3) 是口服有效的二酰基甘油酰基转移酶1 选择性抑制剂。T863结合DGAT1的酰基辅酶A 结合位点，抑制三酰甘油在细胞内的合成。
T7785	T-1105	Influenza Virus	Microbiology/Virology
	T-1105 是 T-705 的结构类似物，是一种广谱病毒聚合酶抑制剂，在转化为核糖核苷三磷酸代谢物后抑制 RNA 病毒的聚合酶，有抗病毒活性。
T6833	Favipiravir T-705,6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide,法匹拉韦,法维拉韦	Others; SARS-CoV; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Favipiravir (T-705) 是一种有效且选择性的 RNA 依赖性 RNA 聚合酶抑制剂，用于治疗流感病毒感染。
T14980	CLK-IN-T3	DYRK; CDK	Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
	CLK-IN-T3 是 CLK1、CLK2 和 CLK3 的抑制剂，IC50 为 0.67、15 和 110 nM。 CLK-IN-T3 具有抗癌活性。
T17846	DOTA-(t-butyl)3-PEG5-azide	Others	Others
	DOTA-(t-butyl)3-PEG5-azide is a polyethylene glycol (PEG) derived linker designed specifically for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T7578	REVERSE T3 碘塞罗宁,3,3',5'-triiodo-L-thyronine	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Reverse T3 (3,3',5'-triiodo-L-thyronine) 是由甲状腺素原脱碘后产生的甲状腺激素。它可抑制由其它甲状腺激素类似物引起的新生大鼠心肌细胞中钠电流增加的作用。
T13998	1-(t-Boc-Aminooxy)-3-aminooxy-propane	Others	Others
	1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs[1].
T18656	S-acetyl-PEG2-Boc Tert-Butyl 3-[2-(2-Acetylsulfanylethoxy)Ethoxy]Propanoate,S-Acetyl-PEG2-T-Butyl Ester	Others; PROTAC Linker	Others; PROTAC
	S-acetyl-PEG2-Boc (S-Acetyl-PEG2-T-Butyl Ester) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T8656	CAY10404 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis; Akt; COX	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience; PI3K/Akt/mTOR signaling
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) 是一种有效且高度选择性的 COX-2 和 COX-1 抑制剂。它还是 PKB/Akt 和 MAPK 信号通路的有效抑制剂，可诱导 NSC-LC 细胞凋亡，具有镇痛、抗炎和抗癌活性。
T1814	ICILIN AG-3-5	TRP/TRPV Channel	Membrane transporter/Ion channel
	ICILIN (AG-3-5) 是一种有效的的瞬时受体电位 M8 (TRPM8) 离子通道激动剂。 Icilin 激活 EGTA 中的 TRPM8，该激活作用具有剂量依赖性， EC50=1.4 μM。Icilin 通过调节 T 细胞反应减轻自身免疫性神经炎症。
T39666	Methylamino-PEG3-t-butyl ester Methylamino-PEG3-t-butyl ester
	Methylamino-PEG3-t-butyl ester is a PEG-based linker compound employed for synthesizing PROTACs.
T39075	Bis-PEG3-t-butyl ester Bis-PEG3-t-butyl ester
	Bis-PEG3-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T38924	t-Butyl acetate-PEG3-CH2COOH t-Butyl acetate-PEG3-CH2COOH
	t-Butyl acetate-PEG3-CH2COOH is a polyethylene glycol-derived PROteolysis TArgeting Chimera (PROTAC) linker, specifically designed for incorporation into the synthesis of PROTAC molecules.
T35719	T2AA T2AA,4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol,ZINC95605533	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) 是一种增殖细胞核抗原 (PCNA) 抑制剂，对 PCNA/PIP-box 肽相互作用的 IC50 为 1 μM。 T2AA 通过停止 DNA 复制叉和抑制 PCNA 与 DNA 聚合酶 δ 的相互作用来引起 DNA 复制压力并抑制癌细胞生长。
T1669	Liothyronine sodium 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,三碘代甲状腺素钠盐,Sodium L-3,3',5-triiodothyronine,Cytomel	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) 是甲状腺激素，能够结合并激活 β1 甲状腺激素受体。
T24856	t-Boc-aminooxy-PEG3-propargyl
	t-Boc-aminooxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. PEG Linkers may be useful in the development of antibody-drug conjugates.
T16969	t-Boc-Aminooxy-PEG3-alcohol	Others	Others
	t-Boc-Aminooxy-PEG3-alcohol is a polyethylene glycol (PEG)-based linker compound commonly employed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T25574	Ketomycin Antibiotic R-3,Antibiotic T 86A,Cyclohexenyl-1-glyoxalic acid
	Ketomycin is an antibiotic agent. It is formed from shikimic acid via chorismic acid and prephenic acid.
T17504	Azido-PEG3-S-PEG4-t-butyl ester	Others	Others
	Azido-PEG3-S-PEG4-t-butyl ester is a PEG-based PROTAC linker employed for PROTAC synthesis[1].
T7701	Boc-NH-PEG3 PROTAC Linker 10,2-[2-(2-T-BOC-氨基乙氧基)乙氧基]乙醇	Others; PROTAC Linker	Others; PROTAC
	Boc-NH-PEG3 (PROTAC Linker 10) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 的合成分子。
T17075	Thiol-PEG3-Boc Thiol-PEG3-t-butyl ester	Others	Others
	Thiol-PEG3-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T4976	Umbralisib TGR-1202,RP5264,TGR 1202,TGR1202	PI3K	PI3K/Akt/mTOR signaling
	Umbralisib (TGR 1202) 是一种PI3Kδ抑制剂，IC50=22.2 nM，EC50=24.3 nM。它同时可抑制CK1ε，EC50=6.0 μM。
T34789	Thiol-PEG3-NHBoc t-Boc-N-amido-PEG3-thiol
	t-Boc-N-amido-PEG3-thiol is a PEG derivative containing a Boc-protected amino group and a thiol group.
TNU0604	3’-O-t-Butyldimethylsilyl adenosine
	3'-O-t-Butyldimethylsilyl adenosine is a Nucleoside; Used for special nucleoside modification.
T18382	N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester	Others	Others
	N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].
TNU1269	3’-O-(t-Butyldiphenylsilyl)thymidine
	3'-O-(t-Butyldiphenylsilyl)thymidine is a Nucleoside Derivative - Protected nucleoside w/NH2/OH open.
T24132	HDAC3-IN-T326 HDAC3 inhibitor-T326,T326,HDAC3 IN T326,HDAC3 inhibitor T326,HDAC3INT326
	HDAC3-IN-T326 is a potent and selective HDAC3 inhibitor that acts by increasing NF-κB acetylation and activating HIV gene expression in latent HIV-infected cells.
TNU0727	3’-O-t-Bulyldimethylsilyl thymidine
	Nucleosides - 2’-deoxynucleoside
T16185	N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester)	Others	Others
	N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a polyethylene glycol (PEG)-based PROTAC linker utilized for the synthesis of PROTACs[1].
T64762	P(t-Bu)3 Pd G3
	P(t-Bu)3 Pd G3 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64762，CAS号为 1445086-17-8。
T19571	T3-ATA (S-isomer)	Others	Others
	T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone.
T9720	T3Inh-1	Others	Others
	T3Inh-1 是一种有效的选择性 ppGalNAc-T3 抑制剂，IC50 为 7 µM。 T3Inh-1 可预防乳腺癌细胞。 T3Inh-1 降低组织细胞和小鼠中的 FGF23 激素水平，而不会引起任何毒副作用。
TNU1137	3’-O-(t-Butyldimethylsilyl)-2’-deoxyadenosine
	3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group open.
T17542	Benzyl-N-bis(PEG3-Boc) N-Benzyl-N-bis(PEG3-t-butyl ester)	Others	Others
	Benzyl-N-bis(PEG3-Boc) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TNU0078	N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine
	N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Alkylated nucleoside.
TNU1322	3’-O-t-Bulyldimethylsilyl-4’-C-hydroxymethylthymidine
	3'-O-t-Bulyldimethylsilyl-4'-C-hydroxymethylthymidine is a Nucleoside Derivative - 4'-Modified nucleoside.
T64556	Ir[p-F(t-Bu)-ppy]3
	Ir[p-F(t-Bu)-ppy]3 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64556。
TNU0942	3’-O-(t-Butyldimethylsilyl)-2’-O-methyluridine
	3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine is a Nucleoside Derivative - 2'-Modified nucleoside; Protected nucleoside with NH2/OH group.
TNU1182	2’,3’-Bis-(O-t-butyldimethylsilyl)uridine
	2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.
T18416	N-(Hydroxy-PEG3)-N-Boc-PEG4-Boc N-(Hydroxy-PEG3)-N-Boc-PEG4-t-butyl ester	Others	Others
	N-(Hydroxy-PEG3)-N-Boc-PEG4-Boc is a polyethylene glycol (PEG) based linker utilized for the synthesis of PROTACs (proteolysis targeting chimeras)[1].
TNU1179	2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine
	Nucleoside Derivatives - Thio-nucleosides, Protected nucleosides with NH2/OH open
T67261	P(t-Bu)3 Pd G4
	Methanesulfonato(tri-t-butylphosphino)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67261。
TNU1180	2’,3’-Bis(O-(t-butyldimethylsilyl)-5-methoxyuridine
	Nucleoside Derivatives - 5-Modified pyrimidine nucleosides, Protected nucleosides with NH2/OH open
TNU1576	2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine
	2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1576。
TNU0943	3’-O-(t-Butyldimethylsilyl)-2’-deoxy-2’-fluorouridine
	Nucleoside Derivatives - Fluoro-Modified nucleosides, 2’-Modified nucleosides; Protected nucleosides with NH2/OH group
TNU1294	2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone
	2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone is a Carbohydrate Derivative.
TNU0601	5’-O-(4,4’-Dimethoxytrityl)-3’-O-t-butyldimethylsilyl adenosine
	Nucleoside; Used for special nucleoside or RNA modification
TNU1283	3’-O-(t-Butyldimethylsilyl)-2’-O-(2-methoxyethyl) uridine
	3'-O-(t-Butyldimethylsilyl)-2'-O-(2-methoxyethyl) uridine is a Nucleoside Derivative - Protected nucleoside w/NH2/OH open; 2'-Modified nucleoside.
TNU1323	3’,5’-Bis(O-t-butyldimethylsilyl)-4’-C-hydroxymethyl thymidine
	3',5'-Bis(O-t-butyldimethylsilyl)-4'-C-hydroxymethyl thymidine is a Nucleoside Derivative - 4'-Modified nucleoside; Protected nucleoside w/NH2/OH open.

化合物

Cat.No: T24131

Synonym: HDAC3 inhibitor T247,HDAC3 inhibitor-T247,HDAC3 IN T247,T247

Target: Histone Demethylase, Antiviral

Cat.No: T4681

Synonym: DGAT-3,DGAT-1 inhibitor

Target: Acyltransferase, Transferase

Cat.No: T7785

Target: Influenza Virus

Cat.No: T6833

Synonym: T-705,6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide,法匹拉韦,法维拉韦

Target: Others, SARS-CoV, Influenza Virus, DNA/RNA Synthesis

Cat.No: T14980

Target: DYRK, CDK

DOTA-(t-butyl)3-PEG5-azide

Cat.No: T17846

Target: Others

Cat.No: T7578

Synonym: 碘塞罗宁,3,3',5'-triiodo-L-thyronine

Target: Thyroid hormone receptor(THR)

1-(t-Boc-Aminooxy)-3-aminooxy-propane

Cat.No: T13998

Target: Others

S-acetyl-PEG2-Boc

Cat.No: T18656

Synonym: Tert-Butyl 3-[2-(2-Acetylsulfanylethoxy)Ethoxy]Propanoate,S-Acetyl-PEG2-T-Butyl Ester

Target: Others, PROTAC Linker

Cat.No: T8656

Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Target: Apoptosis, Akt, COX

Cat.No: T1814

Synonym: AG-3-5

Target: TRP/TRPV Channel

Methylamino-PEG3-t-butyl ester

Cat.No: T39666

Synonym: Methylamino-PEG3-t-butyl ester

Bis-PEG3-t-butyl ester

Cat.No: T39075

Synonym: Bis-PEG3-t-butyl ester

t-Butyl acetate-PEG3-CH2COOH

Cat.No: T38924

Synonym: t-Butyl acetate-PEG3-CH2COOH

Cat.No: T35719

Synonym: T2AA,4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol,ZINC95605533

Target: DNA/RNA Synthesis

Liothyronine sodium

Cat.No: T1669

Synonym: 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,三碘代甲状腺素钠盐,Sodium L-3,3',5-triiodothyronine,Cytomel

Target: Thyroid hormone receptor(THR)

t-Boc-aminooxy-PEG3-propargyl

Cat.No: T24856

t-Boc-Aminooxy-PEG3-alcohol

Cat.No: T16969

Target: Others

Cat.No: T25574

Synonym: Antibiotic R-3,Antibiotic T 86A,Cyclohexenyl-1-glyoxalic acid

Azido-PEG3-S-PEG4-t-butyl ester

Cat.No: T17504

Target: Others

Cat.No: T7701

Synonym: PROTAC Linker 10,2-[2-(2-T-BOC-氨基乙氧基)乙氧基]乙醇

Target: Others, PROTAC Linker

Cat.No: T17075

Synonym: Thiol-PEG3-t-butyl ester

Target: Others

Cat.No: T4976

Synonym: TGR-1202,RP5264,TGR 1202,TGR1202

Target: PI3K

Thiol-PEG3-NHBoc

Cat.No: T34789

Synonym: t-Boc-N-amido-PEG3-thiol

3’-O-t-Butyldimethylsilyl adenosine

Cat.No: TNU0604

N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester

Cat.No: T18382

Target: Others

3’-O-(t-Butyldiphenylsilyl)thymidine

Cat.No: TNU1269

Cat.No: T24132

Synonym: HDAC3 inhibitor-T326,T326,HDAC3 IN T326,HDAC3 inhibitor T326,HDAC3INT326

3’-O-t-Bulyldimethylsilyl thymidine

Cat.No: TNU0727

N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester)

Cat.No: T16185

Target: Others

Cat.No: T64762

T3-ATA (S-isomer)

Cat.No: T19571

Target: Others

Cat.No: T9720

Target: Others

3’-O-(t-Butyldimethylsilyl)-2’-deoxyadenosine

Cat.No: TNU1137

Benzyl-N-bis(PEG3-Boc)

Cat.No: T17542

Synonym: N-Benzyl-N-bis(PEG3-t-butyl ester)

Target: Others

N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine

Cat.No: TNU0078

3’-O-t-Bulyldimethylsilyl-4’-C-hydroxymethylthymidine

Cat.No: TNU1322

Ir[p-F(t-Bu)-ppy]3

Cat.No: T64556

3’-O-(t-Butyldimethylsilyl)-2’-O-methyluridine

Cat.No: TNU0942

2’,3’-Bis-(O-t-butyldimethylsilyl)uridine

Cat.No: TNU1182

N-(Hydroxy-PEG3)-N-Boc-PEG4-Boc

Cat.No: T18416

Synonym: N-(Hydroxy-PEG3)-N-Boc-PEG4-t-butyl ester

Target: Others

2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine

Cat.No: TNU1179

Cat.No: T67261

2’,3’-Bis(O-(t-butyldimethylsilyl)-5-methoxyuridine

Cat.No: TNU1180

2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine

Cat.No: TNU1576

3’-O-(t-Butyldimethylsilyl)-2’-deoxy-2’-fluorouridine

Cat.No: TNU0943

2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone

Cat.No: TNU1294

5’-O-(4,4’-Dimethoxytrityl)-3’-O-t-butyldimethylsilyl adenosine

Cat.No: TNU0601

3’-O-(t-Butyldimethylsilyl)-2’-O-(2-methoxyethyl) uridine

Cat.No: TNU1283

3’,5’-Bis(O-t-butyldimethylsilyl)-4’-C-hydroxymethyl thymidine

Cat.No: TNU1323

Cat. No.	Product Name	Target	Signaling Pathways
T1653	Liothyronine Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine	Thyroid hormone receptor(THR); Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Liothyronine (Tresitope) 是一种有效的甲状腺激素，能够激活 β1 甲状腺激素受体 (TRβ1)。
T13060	T3 Acyl glucuronide	Others	Others
	T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite
T3S1250	Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside 麦冬苷元-3-O-Α-L-吡喃鼠李糖基(1→2)-Β-D-吡喃葡萄糖苷,Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside	Others	Others
	Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) 是一种从麦冬根中取得的萜类糖苷，对心血管系统有良好的药理作用。
T3S0289	Araloside X	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radi
T3S1541	rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-m,(7S,7'R)-双(3,4-亚甲二氧苯基)-rel-(8R,8'R)-二甲基四氢呋喃	Others	Others
	rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan 为肉豆蔻果实中发现的化学成分。
T3S0625	Acoforestinine
	Acoforestinine is a natural product from Aconitum handelianum.
T3S1925	Schisantherin E	Others	Others
	Schisantherin E is an organic compound obtained from the active fraction of Schisandra sphenanthera Rehd. et Wils. fruit.
T3S0964	Thermopsoside Chrysoeriol-7-O-glucoside	Others	Others
	Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system.Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border membrane, apigenin-7-O-d-glucoside can inhibit alpha-amylase activity; they can enhance norepinephrine-induced lipolysis in fat cells.
TN7074	(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid	Antibiotic	Microbiology/Virology
	(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid 对克氏锥虫的 EC50 值为 73.5 μM。
TN1257	3-O-Acetyl-α-boswellic acid 3-O-Acetyl-alpha-boswellic acid,α-Boswellic acid acetate,乙酰基-ALPHA-乳香酸	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	3-O-Acetyl-α-boswellic acid (α-Boswellic acid acetate) 能够抑制 T 细胞功能，具有很强的抗炎作用。
TN3209	3′,4′,7-Trihydroxyflavone	ATPase; Others; p38 MAPK; NF-κB	MAPK; Membrane transporter/Ion channel; NF-κB; Others
	3',4',7-Trihydroxyflavone 是分离自蚕豆荚的黄酮苷元化合物。
T13818	Phytohemagglutinin PHA-M,植物血球凝集素,PHA,植物血凝素	Apoptosis	Apoptosis
	Phytohemagglutinin (PHA-M) 是一种普通豆菜豆的主要种子凝集素，聚集在子叶的薄壁细胞中。它是一种 T 细胞激活剂，能够刺激人单核白细胞，可诱导 ChAT mRNA 表达，增强 ACh 合成。
T2S1792	Lycobetaine 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐	Antibacterial	Microbiology/Virology
	Lycobetaine (Ungeremine) 是一种潜在的抗罗克福尔青霉和黑曲霉的生物杀菌剂。它对柱状黄杆菌有很强的抗菌活性。它有效地靶向哺乳动物以及细菌I 型和II 型拓扑异构酶。它显示出强烈的乙酰胆碱酯酶抑制活性（IC(50) 值为 0.35 microM）。它具有抗原生动物活性，在体外试验中对Trypanosoma brucei rhodesiense、T. cruzi 表现出良好的活性。
T4S0867	Pogostone DHELWANGIN,广藿香酮	Apoptosis; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology
	Pogostone (DHELWANGIN) 是从薄荷中分离出，对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。
T3794	Pentagalloylglucose Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖	Influenza Virus	Microbiology/Virology
	1,2,3,4,6-O-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) 存在于多种植物中，具有重要的药理作用。Pentagalloylglucose 表现出显著的抗狂犬病病毒 (RABV) 活性。
T8264	3-Methyl-2-oxovaleric acid	Endogenous Metabolite	Metabolism
	3-Methyl-2-oxovaleric acid 是神经毒素，代谢毒素和酸性原，它是支链氨基酸不完整分解产生的异常代谢物。
TN1702	Glycycoumarin 甘草香豆素	P450; JNK; AMPK; Autophagy	Autophagy; Chromatin/Epigenetic; MAPK; Metabolism; PI3K/Akt/mTOR signaling
	Glycycoumarin 是甘草中的一种香豆素，能直接靶向 T-LAK 细胞源蛋白激酶发挥抗肝癌活性。它通过激活自噬，抑制内质网应激介导的 JNK 和 GSK-3 介导的线粒体途径，来抑制肝细胞脂性凋亡。它是一种雌激素激动剂，对 CYP1A2 和 CYP2B6 有中度抑制作用。
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。
T2S2215	Crebanine	Apoptosis; Others; Akt	Apoptosis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling
	Crebanine 是来自于韦诺萨千金藤的一种生物碱，通过抑制 MAPKs 和 Akt 信号通路表现出抗炎活性，还具有抗心律失常的作用。它可诱导人类癌细胞的 G1阻滞和凋亡。
T14003	15-Acetoxyscirpenol	Caspase	Apoptosis; Proteases/Proteasome
	15-Acetoxyscirpenol, a member of the acetoxyscirpenol moiety mycotoxins (ASMs), potently induces apoptosis and inhibits the growth of Jurkat T cells in a dose-dependent manner. This effect is mediated through the activation of caspases independent of caspase-3[1].
T72459	3-Oxo-hop-22(29)-ene
	3-Oxo-hop-22(29)-ene 是一种yeast α-glucosidase 抑制剂。3-Oxo-hop-22(29)-ene 具有中等的抗克氏锥虫和抗墨西哥利什曼原虫活性。3-Oxo-hop-22(29)-ene 具有微弱的抗炎活性。
T75631	Ganorbiformin B
	Ganorbiformin B是一种具有与灵芝酸相同羊毛甾烷骨架的羊毛甾烷三萜类化合物。其C-3差向异构体灵芝酸T对结核分枝杆菌H37Ra显示出强抗分枝杆菌活性。
T73730	Distamycin A
	Distamycin A (NSC-82150)为一种寡肽抗生素及小沟结合剂，其结合B型DNA，并倾向于A/T富集区。Distamycin A能调节烯二炔诱导DNA切割位点并促进细胞凋亡。
T75632	Ganoderic acid T1
	Ganoderic acid T1是Ganoderic acid T的去乙酰化衍生物，具有促进癌细胞凋亡(apoptosis)的功能。它通过降低线粒体膜电位以及激活caspase-9和caspase-3来引发细胞凋亡，并增加细胞内ROS的产生，从而表现出促氧化活性和细胞性毒作用，同时减弱抗氧化防御系统。
T36845	Isogarcinol
	Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 μM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed type hypersensitivity, prolongs graft survival in allogeneic skin transplants, suppresses inflammation in collagen-induced arthritis, and reduces clinical symptoms in experimental auto...
TN5033	Skullcapflavone I	IL Receptor; Caspase; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
	Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se
T73402	Flavipin
	Flavipin 是一种芳香烃受体(Ahr)激动剂，可诱导小鼠 CD4+T 细胞和 CD11b+巨噬细胞表达 Ahr 下游基因。Flavipin 抑制 Arid5a 在 Il23a3'UTR 上的稳定功能，这是一种新发现的靶 mRNA。Flavipin 具有清除 DPPH 自由基的能力，IC50值为7.2 μM，对α-葡萄糖苷酶具有较强的抑制作用，IC50值为 33.8 μM。
T36329	Terpendole I
	Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and B. subtilis (MICs = 100 μg/ml for both) but not S. aureus, P. aeruginosa, or K. pneumoniae (MICs = >200 μg/ml for all) or the fungus C. albicans (MIC = 200 μg/ml).1,2 It is cytotoxic to HeLa cells with an IC50 value of 52.6 μM.3 \|1. Tomoda, H., Tabata, N., Yang, D.-J., et al. Ter...
T37609	(rel)-Asperparaline A
	Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces...
T36886	Pestalotin
	Pestalotin is a fungal metabolite originally isolated from P. cryptomeriaecola with diverse biological activities. It induces reducing sugar release in embryoless rice endosperms when used at concentrations ranging from 3 to 100 mg/L and enhances growth of rice seedlings (O. sativa) when used in combination with gibberellin A3 at concentrations ranging from 30 to 500 mg/L. Pestalotin has antifungal activity, reducing the growth of C. albicans, C. neoformans, T. rubrum, and A. fumigatus (MICs = 1...
T35741	Gliovirin
	Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease...
T37452	Stephacidin B
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...
T35415	α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
	α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabol...
T36438	Sporogen-AO 1
	Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO 1 is cytotoxic to HeLa, KB, and NCI H187 cancer cells (IC50s = 8.3, 9, and 5.1 μM, respectively).2,5It is active againstC. albicans(MIC = 4 mM).3 1.Tanaka, S., Wada, K., Marumo, S., et al.Structure of sporogen-ao 1, a sporogenic substance of Aspergillus oryzaeTetrahedron Lett.25(...
T37272	9(S),12(S),13(S)-TriHOME
	9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), ...
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1 1.Balan, J., Ebringer, L., Nemec, P., et al.Ant...

天然产物

Cat.No: T1653

Synonym: Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

T3 Acyl glucuronide

Cat.No: T13060

Target: Others

Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside

Cat.No: T3S1250

Synonym: 麦冬苷元-3-O-Α-L-吡喃鼠李糖基(1→2)-Β-D-吡喃葡萄糖苷,Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside

Target: Others

Cat.No: T3S0289

Target: Calcium Channel

rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan

Cat.No: T3S1541

Synonym: rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-m,(7S,7'R)-双(3,4-亚甲二氧苯基)-rel-(8R,8'R)-二甲基四氢呋喃

Target: Others

Cat.No: T3S0625

Schisantherin E

Cat.No: T3S1925

Target: Others

Cat.No: T3S0964

Synonym: Chrysoeriol-7-O-glucoside

Target: Others

(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid

Cat.No: TN7074

Target: Antibiotic

3-O-Acetyl-α-boswellic acid

Cat.No: TN1257

Synonym: 3-O-Acetyl-alpha-boswellic acid,α-Boswellic acid acetate,乙酰基-ALPHA-乳香酸

Target: Prostaglandin Receptor

3′,4′,7-Trihydroxyflavone

Cat.No: TN3209

Target: ATPase, Others, p38 MAPK, NF-κB

Phytohemagglutinin

Cat.No: T13818

Synonym: PHA-M,植物血球凝集素,PHA,植物血凝素

Target: Apoptosis

Cat.No: T2S1792

Synonym: 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐

Target: Antibacterial

Cat.No: T4S0867

Synonym: DHELWANGIN,广藿香酮

Target: Apoptosis, Antibacterial, Autophagy

Pentagalloylglucose

Cat.No: T3794

Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖

Target: Influenza Virus

3-Methyl-2-oxovaleric acid

Cat.No: T8264

Target: Endogenous Metabolite

Cat.No: TN1702

Synonym: 甘草香豆素

Target: P450, JNK, AMPK, Autophagy

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Cat.No: T2S2215

Target: Apoptosis, Others, Akt

15-Acetoxyscirpenol

Cat.No: T14003

Target: Caspase

3-Oxo-hop-22(29)-ene

Cat.No: T72459

Ganorbiformin B

Cat.No: T75631

Cat.No: T73730

Ganoderic acid T1

Cat.No: T75632

Cat.No: T36845

Skullcapflavone I

Cat.No: TN5033

Target: IL Receptor, Caspase, Prostaglandin Receptor

Cat.No: T73402

Cat.No: T36329

(rel)-Asperparaline A

Cat.No: T37609

Cat.No: T36886

Cat.No: T35741

Cat.No: T37452

α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

Cat.No: T35415

Cat.No: T36438

9(S),12(S),13(S)-TriHOME

Cat.No: T37272

Cat.No: T35779

Cat.No: T35750

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼