store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Reverse T3 (3,3',5'-triiodo-L-thyronine) 是由甲状腺素原脱碘后产生的甲状腺激素。它可抑制由其它甲状腺激素类似物引起的新生大鼠心肌细胞中钠电流增加的作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 347 | 现货 | ||
2 mg | ¥ 497 | 现货 | ||
5 mg | ¥ 813 | 现货 | ||
10 mg | ¥ 1,490 | 现货 | ||
25 mg | ¥ 2,530 | 现货 | ||
50 mg | ¥ 3,720 | 现货 | ||
100 mg | ¥ 5,290 | 现货 |
产品描述 | Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes. |
体外活性 | Reverse T3(T3) pre-conditioning leads to beneficial effects in the liver of brain-dead rats as seen by lower cellular injury and reduced apoptosis, and supports the suggested role of reverse T3(T3) hormone therapy in the management of brain-dead donors[1]. |
细胞实验 | Brain death (BD) was induced in mechanically ventilated rats by inflation of a Fogarty catheter in the epidural space.?T3 (0.1 mg/kg) or vehicle was administered intraperitoneally 2 h prior to BD induction.?After 4 h of BD, serum and liver tissue were collected.?RT-qPCR, routine biochemistry, and immunohistochemistry were performed[1]. |
别名 | 碘塞罗宁, 3,3',5'-triiodo-L-thyronine |
分子量 | 650.97 |
分子式 | C15H12I3NO4 |
CAS No. | 5817-39-0 |
store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 32.55mg/mL(50mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 1.5362 mL | 7.6808 mL | 15.3617 mL | 38.4042 mL |
5 mM | 0.3072 mL | 1.5362 mL | 3.0723 mL | 7.6808 mL | |
10 mM | 0.1536 mL | 0.7681 mL | 1.5362 mL | 3.8404 mL | |
20 mM | 0.0768 mL | 0.384 mL | 0.7681 mL | 1.9202 mL | |
50 mM | 0.0307 mL | 0.1536 mL | 0.3072 mL | 0.7681 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
REVERSE T3 5817-39-0 Endocrinology/Hormones Thyroid hormone receptor(THR) Reverse T 3 THR REVERSE T-3 碘塞罗宁 Thyroid Hormone Receptor inhibit Inhibitor 3′,5′,3-Triiodothyronine 3,3',5'-triiodo-L-thyronine inhibitor