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Search Results for " fumarate "

148

抑制剂 & 化合物

9

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T22746	Tesmilifene fumarate DPPE fumarate	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Tesmilifene fumarate (DPPE fumarate) 是一种 H1C 受体拮抗剂，可增强化疗的细胞毒性且保护正常细胞。
T35346	Tiamulin fumarate Thiamutilin fumarate	Antibacterial	Microbiology/Virology
	Tiamulin fumarate （Thiamutilin fumarate）是一种半合成的二萜类抗生素，具有抗菌活性，抑制蛋白质合成，可用于研究气囊炎。
T13241	UB 165 fumarate UB-165 fumarate,UB165 fumarate	AChR	Neuroscience
	UB 165 fumarate 是 nAChR 的激动剂，α4β2 亚型的部分激动剂，是 α3β2 亚型的全激动剂，其在大鼠脑中测得的结合到 [3H]-nicotine 的 Ki 值为 0.27 nM，可用于研究神经系统疾病。
T39214L	LXE408 fumarate LXE408 fumarate (1799330-15-6 Free base)	Proteasome	Proteases/Proteasome; Ubiquitination
	LXE408 fumarate 是一种口服有效的，非竞争性的，动素体选择性蛋白酶体 (proteasome) 抑制剂。LXE408 fumarate 抑制 L. donovani 蛋白酶体 (IC50=0.04 μM) 和 L. donovani (EC50=0.04 μM)。LXE408 fumarate 具有较弱的透过血脑屏障能力。LXE408 fumarate 具有用于内脏利什曼病 (VL) 研究的潜力。
T0147	Clemastine fumarate HS-592 (fumarate),富马酸氯马斯汀,Meclastine fumarate,Meclastine (fumarate)	Autophagy; Histamine Receptor	Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Clemastine fumarate (Meclastine (fumarate)) 是一种合成乙醇胺，具有抗胆碱能、镇静和组胺 H1 拮抗作用。
T30098	Aplindore Fumarate Aplindore,DAB-452 Fumarate,DAB-452	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Aplindore Fumarate （DAB-452）是一种小分子多巴胺 D2 受体部分激动剂，Aplindore Fumarate 对多巴胺D2 和D3 受体表现出高亲和力，对多巴胺D4、5-羟色胺（5-HT2）和α1-肾上腺素受体表现出低亲和力。Aplindore Fumarate 可用于研究帕金森和精神分裂症。
T0001	Iron(II) fumarate Ferrous fumarate,Iron Fumarate,富马酸铁 (II),富马酸亚铁	Others	Others
	Iron(II) fumarate (Ferrous fumarate) 是一种口服活性膳食补充剂，是一种富马酸的铁 (II) 盐，可用于研究缺铁性贫血。
T41249	Tenofovir alafenamide fumarate GS-7340 fumarate	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Tenofovir alafenamide fumarate (GS-7340 fumarate) 是一种可口服的 Tenofovir 前体化合物。Tenofovir alafenamide fumarate 具有抗 HIV 活性，可用于预防 HIV 感染。
T13385	Zamifenacin fumarate 扎非那星富马酸盐,UK-76654 fumarate	AChR	Neuroscience
	Zamifenacin fumarate (UK-76654 fumarate) 是肠道选择性毒蕈碱M3受体的有效拮抗剂，可显著降低肠易激综合症的结肠蠕动。
T6541	Ibutilide Fumarate Corvert Fumarate,U70226E,富马酸伊布利特	Calcium Channel; Sodium Channel	Membrane transporter/Ion channel; Metabolism
	Ibutilide Fumarate (U70226E) 是一种 III 类抗心律失常药物，可作用于急性心梗阻塞。
T0994	Ketotifen fumarate HC 20511 fumarate,富马酸酮替芬	PDE; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Ketotifen fumarate (HC 20511 fumarate) 是组胺 H1 受体和炎症介质释放的环七噻吩阻滞剂。
T28453L	Propiram fumarate HCl Propiram fumarate HCl(15686-91-6 Free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Propiram fumarate HCl是一种可口服的Opioid receptors激动剂，具有镇痛活性，可用于研究肌肉骨骼疼痛。
T37807	JTV 519 fumarate
	Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo. Hunt et al (2007) K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association. Biochem.J. 404 431 PMID:17313373 \|Chen et al (2008) Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes. Br.J.Pharmacol. 153 915 PMID:17994112 \|...
T2409L	Tenofovir Disoproxil Fumarate GS-1278 Disoproxil Fumarate,Tenofovir DF,富马酸替诺福韦酯	HBV; HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) 是一种核苷酸逆转录酶抑制剂，有潜力研究艾滋病和慢性乙型肝炎。
T13324	VUF11207 fumarate	CXCR; Arrestin	Autophagy; GPCR/G Protein; Immunology/Inflammation
	VUF11207 fumarate 是一种 CXCR7激动剂和高效CXCR7配体，pKi 为 8.1。它可诱导CXCR7的β-arrestin2募集和随后的内在化，pEC50分别为 8.8 和 7.9。
T17038	Tepilamide fumarate XP-23829	Others	Others
	Tepilamide fumarate (XP-23829) 是一种口服具有活性的延胡索酸酯，可用于研究中度到重度慢性斑块银屑病。
T11071	Dofequidar fumarate MS-209	P-gp	Membrane transporter/Ion channel; Neuroscience
	Dofequidar fumarate (MS-209) 是口服活性的喹啉化合物，通过抑制 ABCB1/P-gp 和 ABCC1/MDR 相关蛋白 1 来克服 MDR。
T1771	Ro 48-8071 fumarate	Others	Others
	Ro 48-8071 fumarate 是一种氧化鲨烯环化酶抑制剂(IC50:6.5 nM)。
T22810	GR 89696 fumarate	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	GR 89696 fumarate 是一种高效选择性的κ2 opioid receptor 受体激动剂(IC50 = 0.04 nM)，具有预防瘙痒、体内抗伤害和神经保护作用。
T28258	Org-13011 fumarate Org13011,Org 13011	5-HT Receptor	GPCR/G Protein; Neuroscience
	Org-13011 fumarate1 是 5-HT1A 受体的激动剂，可用于研究神经系统疾病。
T2404	Vonoprazan fumarate 富马酸沃诺拉赞,TAK-438	ATPase	Membrane transporter/Ion channel
	Vonoprazan fumarate (TAK-438) 是一种新型 P-CAB（钾竞争性酸阻滞剂），可可逆地抑制 H+/K+、ATP 酶。
T4271	Diroximel fumarate Diroximel Fumarete	Others	Others
	Diroximel fumarate (Diroximel Fumarete) 是一种控释制剂，是口服具有活力的富马酸单乙酯的前体药物。它被认为与其活性代谢物富马酸二甲酯的活性等效。它具有良好的安全性和有效性，具有研究多发性硬化的潜力。
T27753	KT-362 fumarate KT 362,KT362,KT-362	Potassium Channel; Calcium Channel; Sodium Channel	Membrane transporter/Ion channel; Metabolism
	KT-362 fumarate 是一种新型化合物，可作为钙通道、钾通道和钠通道的拮抗剂.KT-362 fumarate 通过影响心房肌肉细胞内钙动员导致血管舒张。KT-362 fumarate 对兔子的股动脉和基底动脉条有放松作用。
T11337	Fumarate hydratase-IN-1	Others	Others
	Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM. Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor.
T6242	Rupatadine Fumarate 富马酸卢帕他定,Rinialer,Rupafin,Alergoliber	PAFR; Autophagy; Histamine Receptor	Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Rupatadine Fumarate (Rinialer) 是一种可口服的长效PAF/H1受体的双抑制剂，Ki 值分别为 0.55 μM 和 0.1 μM。它可研究过敏性鼻炎和荨麻疹。
T21254	Vonoprazan Fumarate TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞	Proton pump	Membrane transporter/Ion channel
	Vonoprazan Fumarate (TAK438) 是质子泵的有效抑制剂，是口服有效的高效钾竞争性酸阻断剂，具有抗分泌活性。在 pH 为 6.5 时，它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性，IC50为 19 nM。它被开发用于研究酸相关疾病，如消化性溃疡和胃食管反流病。
T1475	Fesoterodine fumarate Toviaz,SPM 907,富马酸非索罗定	AChR	Neuroscience
	Fesoterodine fumarate (Toviaz) 是可口服的，非亚型选择性的竞争性毒蕈碱受体拮抗剂，用于膀胱过度活动症，对 M1、M2、M3、M4 和 M5 受体的pKi 值分别为 8.0、7.7、7.4、7.3 和 7.5。
T6505	Formoterol fumarate Formoterol Hemifumarate,NSC 299587,Eformoterol Hemifumarate,CGP 25827A,Eformoterol,福美特罗富马酸盐,YM 08316	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Formoterol fumarate (Eformoterol Hemifumarate) 是一种长效的 β2-肾上腺素受体激动剂。
T21023	Bedaquiline fumarate TMC 207,R403323,TMC-207,TMC207,R-403323,贝达喹啉富马酸盐,R 403323	Antibacterial; Antibiotic	Microbiology/Virology
	Bedaquiline fumarate (TMC207) 是二芳基喹啉抗生素，作用于 ATP 合成酶，常用于结核杆菌感染的研究。
T72526	Aliskiren fumarate CGP 60536 fumarate,SPP 100 fumarate,CGP 60536 fumarate ; CGP60536B fumarate ; SPP 100 fumarate,CGP60536B fumarate
	Aliskiren fumarate是一种口服有效、选择性的肾素(renin)抑制剂，IC50值为1.5 nM。适用于高血压、心血管疾病和癌症恶病质的研究。
T40358	Ensitrelvir fumarate S-217622 fumarate
	Ensitrelvir (S-217622) fumarate is a novel orally active inhibitor, targeting the SARS-CoV-2 3CL protease (IC50 = 13 nM). It demonstrates non-covalent and non-peptidic characteristics. This compound represents a pioneering advancement in the development of effective antiviral agents against the SARS-CoV-2 virus.
T37622	F13714 fumarate F13714 fumarate
	F13714 fumarate, a selective biased agonist of the 5-HT1A receptor, exhibits antidepressant-like effects upon single administration in the mouse model of chronic mild stress[1].
T10772L	Cevipabulin fumarate TTI-237 fumarate	Others	Others
	Cevipabulin (TTI-237) fumarate is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).
T27047	Clovoxamine fumarate DU23811 fumarate,DU 23811 fumarate,DU-23811 fumarate	5-HT Receptor; Serotonin Transporter; Norepinephrine	GPCR/G Protein; Neuroscience
	Clovoxamine fumarate (DU 23811 fumarate) 是一种 5-羟色胺再摄取、血清素和去甲肾上腺素抑制剂，具有抗抑郁和抗惊厥活性。
T11045	Dimethyl fumarate-d6 Dimethyl fumarate D6,DMF D6	Others	Others
	Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. can induces upregulation of antioxidant gene expression.
T10319L	Anamorelin Fumarate ONO-7643 Fumarate,RC1291 Fumarate,富马酸阿拉莫林	Others	Others
	Anamorelin Fumarate is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).
T6364L	Desfesoterodine fumarate PNU-200577 fumarate,UNII-607O3D83YQ
	Desfesoterodine fumarate is a bio-active chemical. Detailed information has not been published.
T12618	Quetiapine-d4 fumarate Quetiapine D4 fumarate,富马酸奎硫平 D4	Others	Others
	Quetiapine D4 fumarate is the deuterium labeled Quetiapine fumarate. Quetiapine fumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with antidepressant and anxiolytic.
T19435	Monomethyl fumarate-d3 Monomethyl fumarate D3	Others	Others
	Monomethyl fumarate D3 is a deuterium labeled Monomethyl fumarate.
T69434	Methapyrilene fumarate
	Methapyrilene fumarate is a histamine H1 antagonist with sedative action used as a hypnotic and in allergies. It is a hepatocarcinogen in sufficiently high doses, inducing mutations through an indirect genotoxic mechanism; e.g., via an oxidative mechanism or interaction with chromosomal proteins.
T28759	Sesamodil Sesamodil fumarate,SD-3211,SD 3211,SD3211,DS-4823	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Sesamodil（SD 3211）是一种新型钙拮抗剂，可用于研究高血压。
T36639	Donecopride (fumarate hydrate)
	Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= 3,530 nM) but does bind to 5-HT2Band sigma-2 (σ2) receptors (Ki= 1.6 nM for both) in a panel of 42 neurotransmitter receptors and transporters. Donecopride induces release of soluble amyloid precursor protein-α (sAPP-α) in COS-7 cells transiently expressing 5-HT4with an EC50value...
T9450	NS3861 fumarate
	NS3861 fumarate 是烟碱型乙酰胆碱受体 (nAChRs) 的激动剂。NS3861 fumarate 是α3β4 nAChR 的部分激动剂。与α3β4、α3β2、α4β4、α4β2 的结合Ki 值分别为 0.62、25、7.8、55 nM。
T68397	Xamoterol fumarate
	Xamoterol fumarate is a selective beta-1-adrenergic partial agonist. Because it is a partial agonist, it acts as an agonist when sympathetic activity is low and as an antagonist when sympathetic activity is high. It reduces myocardial ischemia and improves ventricular function in patients with mild to moderate heart failure. In patients with severe heart failure it has been shown to produce benefits in systolic and diastolic function.
T68960	F-15599 Fumarate
	F-15599 Fumarate is a highly selective post-synaptic 5-HT(1A) receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity.
T69576	J-104129 fumarate
	J-104129 fumarate is a potent M3 muscarinic receptor antagonist.
T69306	Lubabegron fumarate
	Lubabegron, also known as LY591281; LY488756 fumarate, is a veterinary drug used to reduce ammonia emissions from animals and their waste. Ammonia emissions are a concern in agricultural production because of detrimental effects on the environment, human health, and animal health. Lubabegron was approved by the U.S. Food and Drug Administration in 2018 for use in feedlot cattle. Lubabegron is a beta-adrenergic receptor agonist that has the effect of increasing the breakdown of fats and increasin...
T36721	Dehydro Amlodipine (fumarate)
	Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine. It is a degradation product formed during storage or when amlodipine is subjected to oxidative or acidic conditions or undergoes photo or electrochemical degradation.
T71087	Onvansertib fumarate
	Onvansertib fumarate is a A polo-like kinase 1 inhibitor, an antineoplastic
T69808	ABT-925 fumarate
	ABT-925, also known as A-37203, BSF-201640; DAT-201; Lu-201640; and A-437203, is a selective dopamine D3 receptor (DRD3) antagonist with an approximately 100-fold higher in vitro affinity for dopamine D₃ versus D₂ receptors. ABT-925 was tested in schizophrenia. ABT-925 is a selective dopamine D₃ receptor antagonist with an approximately 100-fold higher in vitro affinity for dopamine D₃ versus D₂ receptors.

化合物

Tesmilifene fumarate

Cat.No: T22746

Synonym: DPPE fumarate

Target: Histamine Receptor

Tiamulin fumarate

Cat.No: T35346

Synonym: Thiamutilin fumarate

Target: Antibacterial

UB 165 fumarate

Cat.No: T13241

Synonym: UB-165 fumarate,UB165 fumarate

Target: AChR

LXE408 fumarate

Cat.No: T39214L

Synonym: LXE408 fumarate (1799330-15-6 Free base)

Target: Proteasome

Clemastine fumarate

Cat.No: T0147

Synonym: HS-592 (fumarate),富马酸氯马斯汀,Meclastine fumarate,Meclastine (fumarate)

Target: Autophagy, Histamine Receptor

Aplindore Fumarate

Cat.No: T30098

Synonym: Aplindore,DAB-452 Fumarate,DAB-452

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Iron(II) fumarate

Cat.No: T0001

Synonym: Ferrous fumarate,Iron Fumarate,富马酸铁 (II),富马酸亚铁

Target: Others

Tenofovir alafenamide fumarate

Cat.No: T41249

Synonym: GS-7340 fumarate

Target: HIV Protease

Zamifenacin fumarate

Cat.No: T13385

Synonym: 扎非那星富马酸盐,UK-76654 fumarate

Target: AChR

Ibutilide Fumarate

Cat.No: T6541

Synonym: Corvert Fumarate,U70226E,富马酸伊布利特

Target: Calcium Channel, Sodium Channel

Ketotifen fumarate

Cat.No: T0994

Synonym: HC 20511 fumarate,富马酸酮替芬

Target: PDE, Histamine Receptor

Propiram fumarate HCl

Cat.No: T28453L

Synonym: Propiram fumarate HCl(15686-91-6 Free base)

Target: Opioid Receptor

JTV 519 fumarate

Cat.No: T37807

Tenofovir Disoproxil Fumarate

Cat.No: T2409L

Synonym: GS-1278 Disoproxil Fumarate,Tenofovir DF,富马酸替诺福韦酯

Target: HBV, HIV Protease, Reverse Transcriptase

VUF11207 fumarate

Cat.No: T13324

Target: CXCR, Arrestin

Tepilamide fumarate

Cat.No: T17038

Synonym: XP-23829

Target: Others

Dofequidar fumarate

Cat.No: T11071

Synonym: MS-209

Target: P-gp

Ro 48-8071 fumarate

Cat.No: T1771

Target: Others

GR 89696 fumarate

Cat.No: T22810

Target: Opioid Receptor

Org-13011 fumarate

Cat.No: T28258

Synonym: Org13011,Org 13011

Target: 5-HT Receptor

Vonoprazan fumarate

Cat.No: T2404

Synonym: 富马酸沃诺拉赞,TAK-438

Target: ATPase

Diroximel fumarate

Cat.No: T4271

Synonym: Diroximel Fumarete

Target: Others

KT-362 fumarate

Cat.No: T27753

Synonym: KT 362,KT362,KT-362

Target: Potassium Channel, Calcium Channel, Sodium Channel

Fumarate hydratase-IN-1

Cat.No: T11337

Target: Others

Rupatadine Fumarate

Cat.No: T6242

Synonym: 富马酸卢帕他定,Rinialer,Rupafin,Alergoliber

Target: PAFR, Autophagy, Histamine Receptor

Vonoprazan Fumarate

Cat.No: T21254

Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞

Target: Proton pump

Fesoterodine fumarate

Cat.No: T1475

Synonym: Toviaz,SPM 907,富马酸非索罗定

Target: AChR

Formoterol fumarate

Cat.No: T6505

Synonym: Formoterol Hemifumarate,NSC 299587,Eformoterol Hemifumarate,CGP 25827A,Eformoterol,福美特罗富马酸盐,YM 08316

Target: Adrenergic Receptor

Bedaquiline fumarate

Cat.No: T21023

Synonym: TMC 207,R403323,TMC-207,TMC207,R-403323,贝达喹啉富马酸盐,R 403323

Target: Antibacterial, Antibiotic

Aliskiren fumarate

Cat.No: T72526

Synonym: CGP 60536 fumarate,SPP 100 fumarate,CGP 60536 fumarate ; CGP60536B fumarate ; SPP 100 fumarate,CGP60536B fumarate

Ensitrelvir fumarate

Cat.No: T40358

Synonym: S-217622 fumarate

F13714 fumarate

Cat.No: T37622

Synonym: F13714 fumarate

Cevipabulin fumarate

Cat.No: T10772L

Synonym: TTI-237 fumarate

Target: Others

Clovoxamine fumarate

Cat.No: T27047

Synonym: DU23811 fumarate,DU 23811 fumarate,DU-23811 fumarate

Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine

Dimethyl fumarate-d6

Cat.No: T11045

Synonym: Dimethyl fumarate D6,DMF D6

Target: Others

Anamorelin Fumarate

Cat.No: T10319L

Synonym: ONO-7643 Fumarate,RC1291 Fumarate,富马酸阿拉莫林

Target: Others

Desfesoterodine fumarate

Cat.No: T6364L

Synonym: PNU-200577 fumarate,UNII-607O3D83YQ

Quetiapine-d4 fumarate

Cat.No: T12618

Synonym: Quetiapine D4 fumarate,富马酸奎硫平 D4

Target: Others

Monomethyl fumarate-d3

Cat.No: T19435

Synonym: Monomethyl fumarate D3

Target: Others

Methapyrilene fumarate

Cat.No: T69434

Cat.No: T28759

Synonym: Sesamodil fumarate,SD-3211,SD 3211,SD3211,DS-4823

Target: Calcium Channel

Donecopride (fumarate hydrate)

Cat.No: T36639

NS3861 fumarate

Cat.No: T9450

Xamoterol fumarate

Cat.No: T68397

F-15599 Fumarate

Cat.No: T68960

J-104129 fumarate

Cat.No: T69576

Lubabegron fumarate

Cat.No: T69306

Dehydro Amlodipine (fumarate)

Cat.No: T36721

Onvansertib fumarate

Cat.No: T71087

ABT-925 fumarate

Cat.No: T69808

Cat. No.	Product Name	Target	Signaling Pathways
T2769	3-Aminopropionitrile fumarate (2:1) Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,3-氨基丙腈,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate	Others	Others
	3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) 是一种能抑制胶原蛋白(collagen)交联的山黧豆素。
T40712	Diethyl fumarate	Others	Others
	Diethyl fumarate 是农药马拉硫磷的分解产物。 Diethyl fumarate 会在皮肤上引起非免疫性接触性荨麻疹。
T12095	Monomethyl fumarate	GPR; Drug Metabolite	Endocrinology/Hormones; GPCR/G Protein; Metabolism
	Monomethyl fumarate 是 Dimethyl fumarate 的活性代谢产物。Monomethyl fumarate 是一种 GPR109A 激动剂。Monomethyl fumarate 是一种 GPR109A 激动剂具有用于多种神经保护途径和其他视网膜疾病模型的潜力。
T0492	Dimethyl fumarate 富马酸二甲酯,DMF	Reactive Oxygen Species; HIV Protease; Nrf2; Endogenous Metabolite; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Dimethyl fumarate (DMF) 是具有口服活性且可透过血脑屏障的Nrf2激活剂，可诱导抗氧化剂基因表达上调。它是一种富马酸盐衍生物，可作抗炎和免疫调节剂，可研究多发性硬化症。
TN6813	Monoethyl fumarate
	Monoethyl fumaric acid is a natural product.
T3763	Fumaric acid Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,反丁烯二酸,Donitic acid,Allomaleic acid,富马酸	Endogenous Metabolite	Metabolism
	Fumaric acid (2-Butenedioic acid) 与烟酸酶缺乏症相关，是癌症相关的内源性代谢物。
T20880	Mesaconic acid 中康酸,Methylfumaric acid,Mesaconate,Kyselina mesakonova	Others	Others
	Mesaconic acid (Methylfumaric acid) 被用作阻燃剂，因为最近的研究表明这种酸是富马酸盐还原的竞争性抑制剂。
T4838	(S)-Malic acid L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸	Others; Endogenous Metabolite	Metabolism; Others
	(S)-Malic acid ((S)-2-Hydroxysuccinic acid) 是天然存在的二羧酸，是水果酸甜味的来源，常用作食品添加剂。
T81570	Paecilaminol FKI-0550
	Paecilaminol (FKI-0550) 为一种高效的 NADH 富马酸还原酶 (NADH-fumarate reductase) 抑制剂，其对蛔虫 (Ascaris suum) NADH 富马酸还原酶展现了 5.1 μM 的 IC50 值。

天然产物

3-Aminopropionitrile fumarate (2:1)

Cat.No: T2769

Synonym: Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,3-氨基丙腈,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate

Target: Others

Diethyl fumarate

Cat.No: T40712

Target: Others

Monomethyl fumarate

Cat.No: T12095

Target: GPR, Drug Metabolite

Dimethyl fumarate

Cat.No: T0492

Synonym: 富马酸二甲酯,DMF

Target: Reactive Oxygen Species, HIV Protease, Nrf2, Endogenous Metabolite, Autophagy

Monoethyl fumarate

Cat.No: TN6813

Cat.No: T3763

Synonym: Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,反丁烯二酸,Donitic acid,Allomaleic acid,富马酸

Target: Endogenous Metabolite

Cat.No: T20880

Synonym: 中康酸,Methylfumaric acid,Mesaconate,Kyselina mesakonova

Target: Others

Cat.No: T4838

Synonym: L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸

Target: Others, Endogenous Metabolite

Cat.No: T81570

Synonym: FKI-0550

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