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103

抑制剂 & 化合物

18

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T7313	Enclomiphene citrate 恩氯米芬柠檬酸盐,Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate	Estrogen Receptor/ERR	Endocrinology/Hormones
	Enclomiphene citrate (trans-Clomiphene citrate) 是口服具有活力的 oestrogen receptor 拮抗剂，具有抗雌激素活性。
T0768	Oxolamine citrate 柠檬酸奥索拉明,AF-438 citrate,SKF-9976 citrate	Others	Others
	Oxolamine citrate (AF-438 citrate) 是一种止咳剂，也表现出抗炎作用，可用于呼吸道疾病的研究。
T2398	Tofacitinib Citrate CP-690550 citrate,柠檬酸托法替尼,枸橼酸托法替尼,Tasocitinib citrate,Tofacitinib (CP-690550) Citrate	Apoptosis; Influenza Virus; JAK; Antibacterial; Antifungal	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Tofacitinib Citrate (CP-690550 citrate) 是 JAK1/2/3抑制剂，IC50分别为112，20 和 1 nM。它具有抗菌，抗真菌和抗病毒活性。
T1193	Clomiphene citrate NSC 35770,枸橼酸氯米芬,Clomifene citrate	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Clomiphene citrate (NSC 35770) 是一种雌激素受体调节剂。
T0464	Carbetapentane citrate 托可拉斯,Pentoxyverine citrate,咳必清	AChR	Neuroscience
	Carbetapentane citrate (Pentoxyverine citrate) 能够选择性抑制咳嗽中枢，具有轻度的阿托品样作用和局麻作用。
T0467	Sildenafil citrate UK-92480 citrate,西地那非柠檬酸盐,枸橼酸西地那非	Apoptosis; PDE; Autophagy	Apoptosis; Autophagy; Metabolism
	Sildenafil citrate (UK-92480 citrate) 是一种磷酸二酯酶 5 抑制剂，IC50为 5.22 nM。
T7412	Tandospirone citrate SM-3997 citrate,坦度螺酮柠檬酸盐,枸橼酸坦度螺酮	5-HT Receptor	GPCR/G Protein; Neuroscience
	Tandospirone citrate (SM-3997 citrate) 是一种选择性5-HT1A 受体激动剂，Ki 为27 nM。
T6597	Mosapride Citrate TAK-370 citrate,AS-4370 citrate,4-氨基-5-氯-2-乙氧基-N-[[4-(4-氟苄基)-2-吗啉基]甲基]苯甲酰胺枸橼酸盐,莫沙必利柠檬酸盐,AS-4370	5-HT Receptor	GPCR/G Protein; Neuroscience
	Mosapride Citrate (TAK-370 citrate) 是一种促胃肠动力药，用作选择性 5HT4 激动剂。
T2016	MLN9708 Ixazomib Citrate	Proteasome	Proteases/Proteasome; Ubiquitination
	MLN9708 (Ixazomib Citrate) 抑制 20S 蛋白酶体的糜蛋白酶样蛋白水解 (β5) 位点 (Ki50=0.93 nM, IC50=3.4 nM/)。 MLN9708 的生物活性形式是水溶液或血浆中的 MLN2238。
T13898	SPD-473 citrate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.
T9579L	GLP-1 receptor agonist 9 citrate GLP-1 receptor agonist 9 citrate (2401892-71-3 Free base)	Glucagon Receptor	GPCR/G Protein
	GLP-1 receptor agonist 9 citrate 是 GLP-1 的激动剂。
T12017	Methyllycaconitine citrate MLA	AChR	Neuroscience
	Methyllycaconitine citrate (MLA) 是一种可穿过血脑屏障的 α7 神经元烟碱乙酰胆碱受体（α7nAChR）拮抗剂，可用于研究神经系统疾病。
T0056	Oxeladin citrate	Others	Others
	Oxeladin citrate 是止咳剂，能够对各种病因引发咳嗽进行有效研究。
T1420	Diethylcarbamazine citrate Caritrol,枸橼酸乙胺嗪,Loxuran,Dicarocide	Lipoxygenase; COX; Parasite	Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	Diethylcarbamazine citrate (Caritrol) 是驱肠虫药，主要用作治疗丝虫病的柠檬酸盐，是丝虫微丝蚴的花生四烯酸代谢抑制剂。
T0428	Alverine citrate NSC 35459,枸橼酸阿尔维林	5-HT Receptor	GPCR/G Protein; Neuroscience
	Alverine citrate (NSC 35459) 是5-HT1A 受体的拮抗剂，IC50值为101 nM，用于功能性胃肠道疾病。
T6618	Orphenadrine Citrate Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君	AChR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Orphenadrine Citrate (Flexon) 是NMDA 受体拮抗剂，Ki 为6.0μM，还是HERG 钾离子通道阻断剂。它是一种骨骼肌松弛剂，它作用于中枢神经系统以产生肌肉松弛作用。
T16539	Piperazine citrate	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Piperazine citrate 是一种六元环化合物，有驱虫的作用。
T64923	Sodium citrate Citrosodine,Natrocitral,柠檬酸钠	Others	Others
	Sodium citrate (Natrocitral) 是柠檬酸的钠盐。Sodium citrate 诱导G2/M 期和S 期细胞凋亡和细胞周期阻滞。Sodium citrate 通过降低抗氧化酶活性引起肝脏氧化损伤。
T8397	Ixazomib citrate 枸橼酸艾沙佐米,MLN9708	Proteasome; Autophagy	Autophagy; Proteases/Proteasome; Ubiquitination
	Ixazomib citrate (MLN9708) 是 Ixazomib 的前药，是20S 蛋白酶体胰凝乳蛋白酶样蛋白水解β5位点的可逆抑制剂，IC50为3.4 nM 和Ki 为0.93 nM。
T40468	Arimoclomol citrate Arimoclomol citrate,BRX-220 citrate
	Arimoclomol citrate (BRX-220 citrate) is a heat shock protein (HSP) co-inducer that acts by enhancing Hsp expression and directly impacting protein aggregation, clearance of misfolded assemblies, and the proteasome-ubiquitin system. This compound is known for its ability to protect motor neurons.
T38422	Nelonicline citrate ABT-126 citrate
	Nelonicline citrate (ABT-126) is an orally active and selective α7 nicotinic receptor agonist, demonstrating a high affinity for α7 nAChRs in the human brain (Ki = 12.3 nM). This compound is utilized in the research of schizophrenia and Alzheimer's disease.
T1120L2	Dacarbazine citrate DTIC citrate
	Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Soft tissue sarcoma (cancer of muscles
TMIH-0615	Zuclomiphene-d4 Citrate cis-Clomiphene-d4 Citrate
	Zuclomiphene-d4 Citrate 是 Zuclomiphene Citrate 的氘代化合物。Zuclomiphene Citrate 的 CAS 号为 14158-66-8。
T26277L	Tilarginine citrate L-Ng-monomethyl arginine citrate
	Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.
T33688	Nitromifene Citrate Parke davis CI-628,CI-628 citrate,CI 628 citrate,CI628 citrate
	Nitromifene Citrate is a nonsteroidal estrogen antagonist most commonly used as a research tool in animal studies.
T0835	Tamoxifen Citrate Tamoxifen Z-isomer citrate,ICI 46474,ICI 46474 Citrate,枸橼酸他莫昔芬,他莫昔芬柠檬酸盐	Apoptosis; Estrogen Receptor/ERR; HSP; Estrogen/progestogen Receptor; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Endocrinology/Hormones; Metabolism
	Tamoxifen Citrate 是一种口服有效的，选择性雌激素受体调节剂，可阻断乳腺细胞中的雌激素作用，并可激活如骨骼、肝脏和子宫细胞中的雌激素活性。它是 Hsp90激活剂，可增强 Hsp90 分子伴侣 ATPase 的活性，可激活自噬和诱导凋亡。
T34943	Triisocetyl citrate Jeechem TISC,Citmol 316,Triisohexadecyl citrate
	Triisocetyl citrate is a bioactive chemical.
T27175	Dilopetine Citrate E-6006 Citrate,E-6039,E6039,E 6039
	Dilopetine Citrate, a tachykinin receptor modulator and a neurokinin receptor modulator, is used potentially for the treatment of depression.
T27294	Ethoheptazine Citrate Wy-401,Wy 401,Aethoheptazin,Zactane citrate,Wy401
	Ethoheptazine Citrate, also known as Zactane and WY-401, is a mycolic acid synthesis inhibitor used to treat tuberculosis.
T19280	Diethyl aminoethyl hexanoate citrate DA-6 citrate,胺鲜酯柠檬酸盐,2-Diethylaminoethyl hexanoate citrate	Others	Others
	Diethyl aminoethyl hexanoate citrate (2-Diethylaminoethyl hexanoate citrate) 是一种植物生长调节剂，能够刺激不定芽的再生。
T12436	PF-543 Citrate Sphingosine Kinase 1 Inhibitor II Citrate	S1P Receptor	GPCR/G Protein
	PF-543 Citrate is an inhibitor of sphingosine-competitive SPHK1(IC50 of 2 nM ).
T35344	Maropitant citrate	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Maropitant citrate 是一种新型神经激肽 1 型 (neurokinin type-1, NK1) 受体拮抗剂，具有抗炎和镇痛特性。
T69849	Deptropine citrate
	Deptropine citrate is a well-known H1-histamine receptor antagonist and muscarinic receptor antagonist. It is prescribed frequently for treatment of asthma. Recently deptropine has garnered interest as a potential treatment for breast cancer. In vitro studies have shown deptropine citrate has inhibitory effects on cell viability and mammosphere formation in Breast Cancer Stem Cells (BCSCs). However, it does not seem to inhibit the self-renewal capacity of the breast cancer cell line MDA-MB-231 w...
T6597L	Mosapride citrate dihydrate GR-107719-B,Mosapride Citrate,GR 107719 B,AS 4370,AS-4370,TAK-370
	Mosapride Citrate is a 5-HT4 receptor agonist used to stimulate gastrointestinal motility via acetylcholine. Mosapride Citrate facilitates acetylcholine release from the enteric cholinergic neurons.
T25543	Isoaminile citrate
	Isoaminile citrate 是一种安全有效的中枢镇咳药。在动物实验中，它与 codeine 一样有效，但没有任何呼吸抑制作用。
T70029	Ibrexafungerp citrate
	Ibrexafungerp citrate is a triterpenoid antifungal. Similarly to echinocandins, it inhibits the synthesis of 1,3-β-d-glucan. However, it binds to a different site on the enzyme than echinocandins, resulting in limited cross-resistance. Ibrexafungerp exerts concentration-dependent fungicidal activity against Candida species and retains in vitro activity against most fluconazole-resistant strains.
T71183	Simpinicline citrate
	Simpinicline citrate is a nicotinic acetylcholine receptor (nAChR) agonist.
T70773	Noberastine citrate
	Noberastine citrate, a histamine H1 antagonist, has potent and specific peripheral antihistaminic activity. Noberastine, a furan derivative of nor-astemizole (an astemizole metabolite), has been shown to have a more rapid onset, and shorter duration of action than astemizole with peak antihistaminic activity at 4h following ingestion. Noberastine is rapidly absorbed and the peak plasma levels are obtained within 2 h of oral dosing. In preclinical studies Noberastine has been shown to lack centra...
T20885	Acetyltriethyl citrate
	Acetyltriethyl citrate is a biochemical.
T34957	Tristearyl citrate
	Tristearyl citrate is a bioactive chemical.
T13415	Zuclomiphene citrate	Others	Others
	Zuclomiphene citrate is a cis isomer of Clomiphene citrate, and has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer.
T31617	Elzasonan citrate
	Elzasonan Citrate is a selective 5-HT1B and 5-HT1D receptor antagonist for the treatment of depression.
T36062	N-Desmethyl Sildenafil (citrate)
	N-Desmethyl sildenafil is a major metabolite of sildenafil . N-Desmethyl sildenafil is formed via oxidative metabolism of sildenafil by the cytochrome (CYP) P450 isoforms CYP3A4, CYP3A5, and CYP3A7.
T26364	NS-2359 citrate GSK-372475,GSK 372475 citrate,NS2359,GSK 372475,NS 2359,GSK372475,NS-2359
	NS-2359 is a serotonin-norepinephrine-dopamine reuptake inhibitor.
T68427	MLN-3897 citrate
	MLN-3897 citrate is a C-C Motif Chemokine Receptor 1 (CCR1) antagonist potentially for the treatment of multiple sclerosis and rheumatoid arthritis.
T31784	Ferric citrate JTT 751
	Ferric citrate as a source of iron used in cell culture applications can provide iron with a less toxic form compared to free iron salts.
T27025	Cizolirtine citrate E-4018,E4018,E 4018
	Cizolirtine is a calcitonin gene-related peptide antagonist. Cizolirtine may be useful for alleviating some neuropathic somatosensory disorders, in particular cold allodynia, with a reduced risk of undesirable side effects. Cizolirtine inhibits the spinal
T69696	TAS-108 citrate
	TAS-108, also known as SR16234, is a synthetic, antiestrogenic steroidal compound with potential antitumor activity. TAS-108 binds to and inhibits estrogenic receptor alpha (ERa), mainly expressed in the mammary gland and uterus and upregulated in estrogen-dependent tumors. Blockage of ERa by TAS-108 prevents the binding and effects of estrogen and may lead to an inhibition of estrogen-dependent cancer cell proliferation. TAS-108 also is a partial agonist of the estrogenic receptor beta (ERb), e...
T71775	Morantel citrate
	Morantel citrate is a potent non-binding site acetylcholine (ACh) receptor agonist that inhibits fumarate reductase.
T20342	Acetyltributyl citrate
	Acetyltributyl citrate is an agent of plasticizer.

化合物

Enclomiphene citrate

Cat.No: T7313

Synonym: 恩氯米芬柠檬酸盐,Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate

Target: Estrogen Receptor/ERR

Oxolamine citrate

Cat.No: T0768

Synonym: 柠檬酸奥索拉明,AF-438 citrate,SKF-9976 citrate

Target: Others

Tofacitinib Citrate

Cat.No: T2398

Synonym: CP-690550 citrate,柠檬酸托法替尼,枸橼酸托法替尼,Tasocitinib citrate,Tofacitinib (CP-690550) Citrate

Target: Apoptosis, Influenza Virus, JAK, Antibacterial, Antifungal

Clomiphene citrate

Cat.No: T1193

Synonym: NSC 35770,枸橼酸氯米芬,Clomifene citrate

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Carbetapentane citrate

Cat.No: T0464

Synonym: 托可拉斯,Pentoxyverine citrate,咳必清

Target: AChR

Sildenafil citrate

Cat.No: T0467

Synonym: UK-92480 citrate,西地那非柠檬酸盐,枸橼酸西地那非

Target: Apoptosis, PDE, Autophagy

Tandospirone citrate

Cat.No: T7412

Synonym: SM-3997 citrate,坦度螺酮柠檬酸盐,枸橼酸坦度螺酮

Target: 5-HT Receptor

Mosapride Citrate

Cat.No: T6597

Synonym: TAK-370 citrate,AS-4370 citrate,4-氨基-5-氯-2-乙氧基-N-[[4-(4-氟苄基)-2-吗啉基]甲基]苯甲酰胺枸橼酸盐,莫沙必利柠檬酸盐,AS-4370

Target: 5-HT Receptor

Cat.No: T2016

Synonym: Ixazomib Citrate

Target: Proteasome

SPD-473 citrate

Cat.No: T13898

Target: Dopamine Receptor

GLP-1 receptor agonist 9 citrate

Cat.No: T9579L

Synonym: GLP-1 receptor agonist 9 citrate (2401892-71-3 Free base)

Target: Glucagon Receptor

Methyllycaconitine citrate

Cat.No: T12017

Synonym: MLA

Target: AChR

Oxeladin citrate

Cat.No: T0056

Target: Others

Diethylcarbamazine citrate

Cat.No: T1420

Synonym: Caritrol,枸橼酸乙胺嗪,Loxuran,Dicarocide

Target: Lipoxygenase, COX, Parasite

Alverine citrate

Cat.No: T0428

Synonym: NSC 35459,枸橼酸阿尔维林

Target: 5-HT Receptor

Orphenadrine Citrate

Cat.No: T6618

Synonym: Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君

Target: AChR, iGluR

Piperazine citrate

Cat.No: T16539

Target: GABA Receptor

Sodium citrate

Cat.No: T64923

Synonym: Citrosodine,Natrocitral,柠檬酸钠

Target: Others

Ixazomib citrate

Cat.No: T8397

Synonym: 枸橼酸艾沙佐米,MLN9708

Target: Proteasome, Autophagy

Arimoclomol citrate

Cat.No: T40468

Synonym: Arimoclomol citrate,BRX-220 citrate

Nelonicline citrate

Cat.No: T38422

Synonym: ABT-126 citrate

Dacarbazine citrate

Cat.No: T1120L2

Synonym: DTIC citrate

Zuclomiphene-d4 Citrate

Cat.No: TMIH-0615

Synonym: cis-Clomiphene-d4 Citrate

Tilarginine citrate

Cat.No: T26277L

Synonym: L-Ng-monomethyl arginine citrate

Nitromifene Citrate

Cat.No: T33688

Synonym: Parke davis CI-628,CI-628 citrate,CI 628 citrate,CI628 citrate

Tamoxifen Citrate

Cat.No: T0835

Synonym: Tamoxifen Z-isomer citrate,ICI 46474,ICI 46474 Citrate,枸橼酸他莫昔芬,他莫昔芬柠檬酸盐

Target: Apoptosis, Estrogen Receptor/ERR, HSP, Estrogen/progestogen Receptor, Autophagy

Triisocetyl citrate

Cat.No: T34943

Synonym: Jeechem TISC,Citmol 316,Triisohexadecyl citrate

Dilopetine Citrate

Cat.No: T27175

Synonym: E-6006 Citrate,E-6039,E6039,E 6039

Ethoheptazine Citrate

Cat.No: T27294

Synonym: Wy-401,Wy 401,Aethoheptazin,Zactane citrate,Wy401

Diethyl aminoethyl hexanoate citrate

Cat.No: T19280

Synonym: DA-6 citrate,胺鲜酯柠檬酸盐,2-Diethylaminoethyl hexanoate citrate

Target: Others

PF-543 Citrate

Cat.No: T12436

Synonym: Sphingosine Kinase 1 Inhibitor II Citrate

Target: S1P Receptor

Maropitant citrate

Cat.No: T35344

Target: Neurokinin receptor

Deptropine citrate

Cat.No: T69849

Mosapride citrate dihydrate

Cat.No: T6597L

Synonym: GR-107719-B,Mosapride Citrate,GR 107719 B,AS 4370,AS-4370,TAK-370

Isoaminile citrate

Cat.No: T25543

Ibrexafungerp citrate

Cat.No: T70029

Simpinicline citrate

Cat.No: T71183

Noberastine citrate

Cat.No: T70773

Acetyltriethyl citrate

Cat.No: T20885

Tristearyl citrate

Cat.No: T34957

Zuclomiphene citrate

Cat.No: T13415

Target: Others

Elzasonan citrate

Cat.No: T31617

N-Desmethyl Sildenafil (citrate)

Cat.No: T36062

NS-2359 citrate

Cat.No: T26364

Synonym: GSK-372475,GSK 372475 citrate,NS2359,GSK 372475,NS 2359,GSK372475,NS-2359

MLN-3897 citrate

Cat.No: T68427

Ferric citrate

Cat.No: T31784

Synonym: JTT 751

Cizolirtine citrate

Cat.No: T27025

Synonym: E-4018,E4018,E 4018

TAS-108 citrate

Cat.No: T69696

Morantel citrate

Cat.No: T71775

Acetyltributyl citrate

Cat.No: T20342

Cat. No.	Product Name	Target	Signaling Pathways
TN7238L	Sanguinarine citrate Sanguinarium citrate,Sanguinarin citrate,Pseudochelerythrine citrate	Antibiotic	Microbiology/Virology
	Sanguinarine citrate (Pseudochelerythrine chloride) 是一种来源于 Sanguinaria Canadensis 的生物碱，具有抗菌、抗炎和镇痛活性，可用于治疗口腔炎、牙龈出血和喉炎等口腔炎症疾病。
T12952	Sodium citrate dihydrate Citric acid trisodium salt dihydrate,Trisodium citrate dihydrate,二水合柠檬酸钠	Antibacterial	Microbiology/Virology
	Sodium citrate dihydrate (Trisodium citrate dihydrate) 是一种抗凝血剂，也用为缓冲剂和食品防腐剂。
T8069	Triethyl citrate	Others	Others
	Triethyl citrate 是一种柠檬酸酯，可在纤维素塑料基纳米复合材料中，作为增塑剂使用。
T20819	Ammonium iron(III) citrate 柠檬酸铁铵,柠檬酸铁 (III) 铵,Ferric ammonium citrate	Others; Ferroptosis	Apoptosis; Others
	Ammonium iron(III) citrate (Ferric ammonium citrate) 是一种非运铁蛋白结合的铁的生理形式，会引起的细胞内铁超负荷从而导致细胞铁死亡，能增强蛋白质产生。
T0256	Citric acid trilithium salt tetrahydrate Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate	Dehydrogenase; GSK-3; HIF/HIF Prolyl-Hydroxylase; Antibacterial; GluR	Chromatin/Epigenetic; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells
	Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) 是一种用于治疗精神疾病的药物。它也是一种医药和建筑材料, 可用于氨基酸定量分析时的梯度洗脱。
T40244	Methyl citrate
	Methyl citrate, obtained from Opuntia ficus-indica var. saboten Makino fruits, serves as a potent Monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 0.23 mM.
TN6870	TRIMETHYL CITRATE
	TRIMETHYL CITRATE is a natural product.
T11589	Hydroxycitric acid tripotassium hydrate 柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate	ATP Citrate Lyase; HIF/HIF Prolyl-Hydroxylase; HIF	Angiogenesis; Chromatin/Epigenetic; Metabolism
	Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) 是一种藤黄果的主要活性成分，也是一种柠檬酸的衍生物。它可竞争性抑制柠檬酸裂解酶 (ATP citrate lyase) ，并具有减肥作用。它有效抑制结石形成，并抑制HIF，具有抗氧化，抗炎和抗肿瘤活性。
T11590	(-)-Hydroxycitric acid Garcinia acid,(-)-羟基柠檬酸	ATP Citrate Lyase	Metabolism
	(-)-Hydroxycitric acid (Garcinia acid) 是Garcinia cambogia 果皮中的主要酸。它是 ATP 柠檬酸裂解酶的竞争性抑制剂，能够抑制脂肪酸的合成，减少脂肪生成，控制食物摄入，从而减轻体重。
T12045	(-)-Hydroxycitric acid lactone 藤黄内酯,Garcinia lactone	ATP Citrate Lyase	Metabolism
	(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种有效的 ATP-柠檬酸裂解酶抑制剂，能够催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A，限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。它是一种减肥药，是一种广受欢迎的减肥食品补充剂。
TN7238	Sanguinarine gluconate	Antioxidant; Antibiotic	Microbiology/Virology; oxidation-reduction
	Sanguinarine gluconate 是一种在许多药用植物中发现的生物碱，具有抗菌抗氧化和抗肿瘤活性。
T5544	2-Furoic acid Furan-2-carboxylic acid,糠酸	Anti-infection; ATP Citrate Lyase; Endogenous Metabolite; Acyltransferase	Metabolism; Microbiology/Virology
	2-Furoic acid (Furan-2-carboxylic acid) 2-Furoic acid 能够降低血清中胆固醇和甘油三酯的水平，具有抗血脂作用。
T4862	Oxaloacetic acid	Endogenous Metabolite	Metabolism
	Oxaloacetic acid 是一种代谢中间体，涉及多种途径，如葡萄糖异生、柠檬酸循环、乙醛酸循环、尿素循环、氨基酸合成和脂肪酸合成。
T4861	trans-Aconitic acid	ATPase; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	trans-Aconitic acid 是反式丙酮酸2-甲基转移酶的底物，存在于正常人尿液中，大量存在于 Reye 综合征和有机酸尿症。
TN1751	Hydroxycitric acid	ERK; p38 MAPK; Fatty Acid Synthase	MAPK; Metabolism
	(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyase, which catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (acetyl-CoA), primary building blocks of fatty acid and cholesterol synthesis.
T79936	Forrestiacids K	ATP Citrate Lyase	Metabolism
	Forrestiacids K, 萜类化合物，源自Pseudotsuga forrestii，作为ATP-citrate lyase (ACL) 的抑制剂。
T79935	Forrestiacids J	ATP Citrate Lyase	Metabolism
	Forrestiacids J为一种特异性抑制ATP-柠檬酸裂解酶 (ACL) 的化合物，其IC50值为2.6 μM。
T82274	Gnetuhainin I
	Gnetuhainin I (Compound 5)是源自Pouzolzia zeylanica的木质素化合物，展现出对ATP柠檬酸裂解酶（ACLY）的显著抑制效果，其半抑制浓度（IC50）值为2.63 μM。

天然产物

Sanguinarine citrate

Cat.No: TN7238L

Synonym: Sanguinarium citrate,Sanguinarin citrate,Pseudochelerythrine citrate

Target: Antibiotic

Sodium citrate dihydrate

Cat.No: T12952

Synonym: Citric acid trisodium salt dihydrate,Trisodium citrate dihydrate,二水合柠檬酸钠

Target: Antibacterial

Triethyl citrate

Cat.No: T8069

Target: Others

Ammonium iron(III) citrate

Cat.No: T20819

Synonym: 柠檬酸铁铵,柠檬酸铁 (III) 铵,Ferric ammonium citrate

Target: Others, Ferroptosis

Citric acid trilithium salt tetrahydrate

Cat.No: T0256

Synonym: Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate

Target: Dehydrogenase, GSK-3, HIF/HIF Prolyl-Hydroxylase, Antibacterial, GluR

Methyl citrate

Cat.No: T40244

TRIMETHYL CITRATE

Cat.No: TN6870

Hydroxycitric acid tripotassium hydrate

Cat.No: T11589

Synonym: 柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate

Target: ATP Citrate Lyase, HIF/HIF Prolyl-Hydroxylase, HIF

(-)-Hydroxycitric acid

Cat.No: T11590

Synonym: Garcinia acid,(-)-羟基柠檬酸

Target: ATP Citrate Lyase

(-)-Hydroxycitric acid lactone

Cat.No: T12045

Synonym: 藤黄内酯,Garcinia lactone

Target: ATP Citrate Lyase

Sanguinarine gluconate

Cat.No: TN7238

Target: Antioxidant, Antibiotic

Cat.No: T5544

Synonym: Furan-2-carboxylic acid,糠酸

Target: Anti-infection, ATP Citrate Lyase, Endogenous Metabolite, Acyltransferase

Oxaloacetic acid

Cat.No: T4862

Target: Endogenous Metabolite

trans-Aconitic acid

Cat.No: T4861

Target: ATPase, Endogenous Metabolite

Hydroxycitric acid

Cat.No: TN1751

Target: ERK, p38 MAPK, Fatty Acid Synthase

Forrestiacids K

Cat.No: T79936

Target: ATP Citrate Lyase

Forrestiacids J

Cat.No: T79935

Target: ATP Citrate Lyase

Cat.No: T82274

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