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Search Results for " tgf-β-2 "
Targets Recommended: TGF-beta/Smad

12

抑制剂 & 化合物

2

天然产物

309

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T8330 BIO-013077-01

6-(3-(6-甲基吡啶-2-基)-1H-吡唑-4-基)喹噁啉

TGF-beta/Smad Stem Cells
BIO-013077-01 是吡唑类TGF-β抑制剂。
T1726 SB-431542

4-[4-(1,3-苯并二唑-5-基)-5-(2-吡啶基)-1H-咪唑-2-基]-苯酰胺水合物,SB 431542

ALK; TGF-beta/Smad Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
SB-431542 是一种 ALK5/TGF-β type I Receptor 的抑制剂 (IC50=94 nM),具有选择性。SB 431542 对 ALK4 和 ALK7 也有抑制活性,但对其他蛋白没有抑制作用。SB 431542 可以用于干细胞的诱导分化。
T6146 Dorsomorphin dihydrochloride

BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

AMPK; Autophagy; TGF-beta/Smad Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells
Dorsomorphin dihydrochloride (BML-275 2HCl) 是一种选择性和 ATP 竞争性的AMPK 抑制剂,Ki 为 109 nM。它诱导自噬,通过靶向抑制 I 型受体ALK2,ALK3和ALK6来抑制 BMP 途径。
T61586 TGFβ-IN-2

TGFβ-IN-2 (Compound 9d) effectively inhibits the accumulation of total collagen induced by TGF-β in NRK-49F cells, with an IC 50 value of 4.31 μM. It also suppresses the in vitro protein expression of COL1A1, α-SMA, and p-Smad3, which are induced by TGF-β. Additionally, TGFβ-IN-2 shows promise as a potential anti-fibrosis compound for in vivo applications through oral administration [1].
T26958 CAY10583

CAY 10583,CAY-10583

CAY10583 is an agonist of leukotriene B4 receptor type 2 (BLT2). CAY10583 directly promotes keratinocyte migration and indirectly enhances fibroblast proliferation by increasing keratinocyte production of bFGF1 and TGF-β, leadng to accelerate wound closur
T11187 EMT inhibitor-2

Others Others
EMT inhibitor-2 inhibits CYP3A4 testosteron and CYP2C9 with IC50s of 49.72 and 5.54 μM, respectively. EMT inhibitor-2 inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from the immunocytes.
T70932 L6H9

L6H9 is a novel inhibitor of myeloid differentiation factor 2 (MD2), suppressing HG-induced expression of ACE and AT1 receptor and Angiotensin II (AngII) production in renal NRK‐52E cells, resulting in the decrease in fibrosis markers such as TGF-β and collagen IV.
T83770 Klotho-derived Peptide 1 (56-87) (human) TFA

KP1 (56-87)

Klotho衍生肽1(KP1)(56-87)是从人类Klotho蛋白质中衍生的肽,具有扰乱TGF-β信号传导的作用。它与TGF-β受体类型1(TGFBR2)和TGF-β受体类型2TGFBR2;Kds分别为1.41和14.6µM)结合。KP1(10 µg/ml)的预孵育抑制TGF-β在NRK-49F大鼠成纤维细胞中诱导的纤维连接蛋白和α-平滑肌肌动蛋白(α-SMA)水平的增加。在体内,KP1(每天1 mg/kg)选择性地定位于受损的肾脏,并减少血清肌酐和血尿素氮水平,这些是肾功能的标志物,同时也减少了小鼠单侧输尿管阻塞(UUO)和单侧缺血-再灌注损伤诱导的肾脏纤维化模型中的肾纤维化。
T21637 SB-505124 hydrochloride

SB-505124 hydrochloride 是TGF-βI 型受体(ALK4,ALK5,ALK7) 的选择性抑制剂,对 ALK4,ALK5 的IC50值分别为 129 nM 和 47 nM,对 ALK1,2,3 或 6 无作用。
T26925 Butaprost

Butaprostum,TR-4979,(R)-Butaprost

Butaprost is a chemical compound that functions as a selective agonist for the prostaglandin E receptor (EP2). It exhibits an EC50 of 33 nM and a Ki of 2.4 μM when interacting with the murine EP2 receptor. However, Butaprost demonstrates lower activity against murine EP1, EP3, and EP4 receptors. Furthermore, it effectively attenuates fibrosis by inhibiting the TGF-β/Smad2 signaling pathway [1] [2] [3].
T74414 S-Allylmercaptocysteine

S-allylmercaptocysteine 是一种从大蒜中提取的有机硫化合物,对各种肺部疾病具有抗炎和抗氧化作用。S-allylmercaptocysteine 通过多种途径发挥抗癌作用,如通过 TGF-β 信号通路诱导癌细胞凋亡 (apoptosis),或通过降低NF-κb 活性和上调 Nrf2 来达到抗炎和抗氧化的作用。
T35438 (5E)-7-Oxozeaenol

(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxozeaenol inhibits proliferation of MCF-7, H460, SF-268, HT-29, and MDA-MB-435 human cancer cells with IC50 values of 4.9, 1.2, 5.6, 4.4, and 5.5 μM, respectively.2 |1. Fakhouri, L., El-Elimat, T., Hurst, D.P., et al. Isolation, semisynthesis, covalent docking and transforming growt...

化合物

BIO-013077-01
Cat.No: T8330
Synonym: 6-(3-(6-甲基吡啶-2-基)-1H-吡唑-4-基)喹噁啉
Target: TGF-beta/Smad
SB-431542
Cat.No: T1726
Synonym: 4-[4-(1,3-苯并二唑-5-基)-5-(2-吡啶基)-1H-咪唑-2-基]-苯酰胺水合物,SB 431542
Target: ALK, TGF-beta/Smad
Dorsomorphin dihydrochloride
Cat.No: T6146
Synonym: BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Target: AMPK, Autophagy, TGF-beta/Smad
TGFβ-IN-2
Cat.No: T61586
Synonym:
Target:
CAY10583
Cat.No: T26958
Synonym: CAY 10583,CAY-10583
Target:
EMT inhibitor-2
Cat.No: T11187
Synonym:
Target: Others
L6H9
Cat.No: T70932
Synonym:
Target:
Klotho-derived Peptide 1 (56-87) (human) TFA
Cat.No: T83770
Synonym: KP1 (56-87)
Target:
SB-505124 hydrochloride
Cat.No: T21637
Synonym:
Target:
Butaprost
Cat.No: T26925
Synonym: Butaprostum,TR-4979,(R)-Butaprost
Target:
S-Allylmercaptocysteine
Cat.No: T74414
Synonym:
Target:
(5E)-7-Oxozeaenol
Cat.No: T35438
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TL0001 dencichine

L-Dencichin,ODAP,Dencichin,三七素

Others; HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism; Others
Dencichine (ODAP) 是抑制从三七中分到的非蛋白氨基酸,可抑制 HIF-prolyl hydroxylase-2 的活性。
T3524 Halofuginone hydrobromide

卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐

Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells
Halofuginone hydrobromid 是Febrifugine 的衍生物,是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂,并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。

天然产物

dencichine
Cat.No: TL0001
Synonym: L-Dencichin,ODAP,Dencichin,三七素
Target: Others, HIF/HIF Prolyl-Hydroxylase
Halofuginone hydrobromide
Cat.No: T3524
Synonym: 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Cat. No. Product Name Species Expression System
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His)

TGFR-2,TGF-beta type II receptor,...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-00413 Latent TGF beta 2 Protein, Mouse, Recombinant (His)

Tgfb-2,Tgf-beta2,TGF...

Mouse HEK293 Cells
TGF beta 2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090.
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant

transforming growth factor β-2,BSC-1 cell ...

Mouse,Rat HEK293 Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n...
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant

Glioblastoma-derived T-cell suppressor factor,TGF-<...

Human HEK293 Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be...
TMPJ-00260 Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated

TGFB2,TGF-β-2,<...

Human HEK293 Cells
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 39-50 KDa and the accession number is P61812.
TMPJ-00333 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

Transforming growth factor-β receptor type II,Tbeta...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
TMPY-00231 TGF beta 2 Protein, Canine, Recombinant (His)

transforming growth factor β2,转化生长因子,T...

Canine HEK293 Cells
TGF beta 2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is A0A8C0RRP5.
TMPJ-00334 TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)

TGF-β receptor type II,Tgfbr2...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.
TMPY-04577 TGF beta 2 Protein, Rhesus, Recombinant (His)

TGF-beta 2,transforming growth factor beta...

Rhesus HEK293 Cells
TGF beta 2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is F6ZJW6.
TMPY-05314 TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated

transforming growth factor β2,TGF...

Mouse HEK293 Cells
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090.
TMPJ-00290 GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)

TRNR2,GDNFR-beta,TGF-β-related ne...

Human HEK293 Cells
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kina...
TMPJ-00238 Lefty-A Protein, Human, Recombinant (His)

Endometrial bleeding-associated factor,TGFB4,TG...

Human HEK293 Cells
Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma cells. Its mRNA expression on the left side of the developing embryo earned the name “Lefty”. The human orthologue was initially identified as Ebaf, Endometrial bleeding associated factor. Lefty contains the six cysteine residues that are conserved among TGF-β related proteins a...
TMPJ-00259 TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated

G-TSF,转化生长因子,Cetermin,Transforming growth factor beta-2<...

Human HEK293 Cells
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P61812.
TMPK-00328 TGFBR2 Protein, Human, Recombinant (mFc & Avi)

TAAD2,LDS2B,LDS2,MFS2,

Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The pred...
TMPK-00329 TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated

LDS2B,TbetaR-II,TGFβR2,L...

Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi...
TMPY-02444 ATF2 Protein, Human, Recombinant (His & GST)

CREB2,CRE-BP1,CREB-2,TREB7,activating tran...

Human Baculovirus Insect Cells
Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has ...
TMPY-01027 Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)

carnitine palmitoyltransferase 1B (muscle),AV080368,Mcp-1

Mouse HEK293 Cells
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. It is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. The granule-derived mouse mast cell proteases-1 and -2 (mMCP-1 and -2) colocalize in similar quantities in mucosal mast cells but micrograms of mMCP-1 compared w...
TMPJ-01290 Neurturin Protein, Human, Recombinant

Neurturin,NRTN

Human E. coli
Neurturin is a member of the GDNF family of ligands, which include glial cell-derived neurotrophic factor (GDNF), Neurturin, Persephin, and Artemin. Neurturin is expressed in both neuronal and nonneuronal tissues. Similarly to other TGFβ family proteins, Neurturin is synthesized as a precursor protein that is cleaved at the dibasic cleavage site (RXXR) to release the carboxyterminal domain. The carboxy terminal domain of Neurturin contains the characteristic seven conserved cysteine residues nec...
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Protein T1,suppression of tumorigenicity 2,Ly84,DER...

Mouse HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02011 CD96 Protein, Human, Recombinant (His)

CD96 molecule,TACTILE

Human HEK293 Cells
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...

Human E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His)

A630052E07Rik,OSF-2,Osf2,PLF,AI74...

Mouse HEK293 Cells
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPY-01717 VEGF164 Protein, Mouse, Recombinant

vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子

Mouse Baculovirus Insect Cells
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-02096 TACI Protein, Human, Recombinant (His)

RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...

Human HEK293 Cells
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His)

KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL...

Human E. coli
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-00751 TrkB Protein, Human, Recombinant (His)

trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...

Human HEK293 Cells
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His)

SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP...

Human HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-04844 BTN3A1 Protein, Human, Recombinant (His)

BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2...

Human HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-05288 PLGF/PGF Protein, Human, Recombinant (aa 19-149)

PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...

Human E. coli
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-02820 SDF-1 Protein, Human, Recombinant (isoform a)

SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1

Human E. coli
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-01935 c-Kit Protein, Human, Recombinant (His)

PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-04356 GSK3B Protein, Human, Recombinant (His)

glycogen synthase kinase 3 beta,glycogen synthase kinase 3 <...

Human Baculovirus Insect Cells
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02500 YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

Gp39,AW208766,Brp39,chitinase 3 like 1

Mouse HEK293 Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01985 CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

FCGR2,FCGR21,CD32A,FCG2,...

Human HEK293 Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04644 PDGFB Protein, Human, Recombinant (His)

platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...

Human P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-05414 NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

D6H12S2489E,NKG2-D,killer cell le...

Mouse Baculovirus Insect Cells
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-01871 IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

interleukin 5 receptor, alpha,IL5R,CD125,CDw12<...

Human HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293)

HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...

Human HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His)

KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...

Human E. coli
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-01359 ST2/IL-1 RL1 Protein, Human, Recombinant (His)

IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-00747 Nectin-2 Protein, Human, Recombinant (His)

PVRR2,Nectin-2,poliovirus receptor-related...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-05427 CD19 Protein, Human, Recombinant (hFc)

CVID3,B4,CD19 molecule

Human HEK293 Cells
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPY-04051 c-Kit Protein, Human, Recombinant (hFc)

SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene h...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
TMPY-00005 FGF-8a Protein, Human, Recombinant

fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-03425 Tau Protein, Human, Recombinant (His)

PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as...

Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPY-01199 CD74 Protein, Human, Recombinant (His)

II,DHLAG,Ia-GAMMA,CD74 molecule, major histocompatibility co...

Human HEK293 Cells
CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
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重组蛋白

TGFBR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00335
Species: Mouse
Expression System: HEK293 Cells
Latent TGF beta 2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00413
Species: Mouse
Expression System: HEK293 Cells
TGF beta 2 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00261
Species: Mouse,Rat
Expression System: HEK293 Cells
TGF beta 2 Protein, Human, Recombinant
Cat.No: TMPJ-00258
Species: Human
Expression System: HEK293 Cells
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00260
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
Cat.No: TMPJ-00333
Species: Mouse
Expression System: HEK293 Cells
TGF beta 2 Protein, Canine, Recombinant (His)
Cat.No: TMPY-00231
Species: Canine
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
Cat.No: TMPJ-00334
Species: Mouse
Expression System: HEK293 Cells
TGF beta 2 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-04577
Species: Rhesus
Expression System: HEK293 Cells
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05314
Species: Mouse
Expression System: HEK293 Cells
GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00290
Species: Human
Expression System: HEK293 Cells
Lefty-A Protein, Human, Recombinant (His)
Cat.No: TMPJ-00238
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
Cat.No: TMPJ-00259
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
Cat.No: TMPK-00328
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
Cat.No: TMPK-00329
Species: Human
Expression System: HEK293 Cells
ATF2 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02444
Species: Human
Expression System: Baculovirus Insect Cells
Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01027
Species: Mouse
Expression System: HEK293 Cells
Neurturin Protein, Human, Recombinant
Cat.No: TMPJ-01290
Species: Human
Expression System: E. coli
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Cat.No: TMPJ-00850
Species: Mouse
Expression System: HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
Cat.No: TMPY-00891
Species: Human
Expression System: HEK293 Cells
CD96 Protein, Human, Recombinant (His)
Cat.No: TMPY-02011
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Cat.No: TMPY-04113
Species: Human
Expression System: E. coli
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01613
Species: Mouse
Expression System: HEK293 Cells
VEGF164 Protein, Mouse, Recombinant
Cat.No: TMPY-01717
Species: Mouse
Expression System: Baculovirus Insect Cells
TACI Protein, Human, Recombinant (His)
Cat.No: TMPY-02096
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
Cat.No: TMPY-00341
Species: Human
Expression System: HEK293 Cells
KRAS Protein, Human, Recombinant (G12D, His)
Cat.No: TMPY-06056
Species: Human
Expression System: E. coli
TrkB Protein, Human, Recombinant (His)
Cat.No: TMPY-00751
Species: Human
Expression System: HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His)
Cat.No: TMPY-01691
Species: Human
Expression System: HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04844
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
Cat.No: TMPY-05288
Species: Human
Expression System: E. coli
SDF-1 Protein, Human, Recombinant (isoform a)
Cat.No: TMPY-02820
Species: Human
Expression System: E. coli
c-Kit Protein, Human, Recombinant (His)
Cat.No: TMPY-01935
Species: Human
Expression System: HEK293 Cells
GSK3B Protein, Human, Recombinant (His)
Cat.No: TMPY-04356
Species: Human
Expression System: Baculovirus Insect Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02500
Species: Mouse
Expression System: HEK293 Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-01985
Species: Human
Expression System: HEK293 Cells
PDGFB Protein, Human, Recombinant (His)
Cat.No: TMPY-04644
Species: Human
Expression System: P. pastoris (Yeast)
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05414
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
Cat.No: TMPY-01871
Species: Human
Expression System: HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-02792
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human, Recombinant (Q61H, His)
Cat.No: TMPY-01888
Species: Human
Expression System: E. coli
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01359
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00747
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05427
Species: Human
Expression System: HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04051
Species: Human
Expression System: HEK293 Cells
FGF-8a Protein, Human, Recombinant
Cat.No: TMPY-00005
Species: Human
Expression System: E. coli
Tau Protein, Human, Recombinant (His)
Cat.No: TMPY-03425
Species: Human
Expression System: E. coli
CD74 Protein, Human, Recombinant (His)
Cat.No: TMPY-01199
Species: Human
Expression System: HEK293 Cells
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