297
8
86
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19609 |
HP-β-CD
羟丙基-β-环糊精,羟丙基-BETA-环糊精,Hydroxypropyl-β-cyclodextrin,Hydroxypropyl betadex |
Others | Others |
HP-β-CD (HP-β-CD) 是一种药物递送载体,可提高稳定性和利用度。 | |||
T19967 |
Fendosal
芬度柳,HP 129,P 71-0129,P71-0129,P-71-0129,HP129,HP-129 |
Immunology/Inflammation related | Immunology/Inflammation |
Fendosal (HP-129) 是一种非甾体抗炎药。在预防性和治疗性辅助诱导的慢性炎症多关节炎模型中,它的活性是阿司匹林的 6.9 至 9.5 倍。 | |||
T26778 |
Besipirdine
HP 749 free base,P-867493,P867493,HP 749,HP749,P 867493 |
Sodium Channel; Adrenergic Receptor | GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
Besipirdine (HP 749 free base)是一种非受体依赖性拟胆碱化合物,具有α-肾上腺素能活性和心血管活性。Besipirdine 抑制电压依赖性钠钾通道,抑制生物胺的摄取。Besipirdine 可减少大鼠的时间表诱导的烦渴,增强中枢神经系统中的胆碱能和肾上腺素能神经传递。 | |||
T1539 |
Iloperidone
伊潘立酮,HP 873 |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Iloperidone (HP 873) 是一种D2/5-HT2受体拮抗剂,是非典型抗精神病药,可治疗精神分裂症。 | |||
T25507 |
HP 228
HP-228,Ac-Nle-gln-his-D-phe-arg-D-trp-gly-NH2,HP228 |
||
HP 228 is a heptapeptide by inhibits the induction of nitric oxide synthase. | |||
T21556 |
Hydroxytacrine maleate
Velnacrine maleate,HP 029 maleate |
AChE | Neuroscience |
Hydroxytacrine maleate (Velnacrine maleate) 是一种胆碱酯酶(cholinesterase) 抑制剂,可增强啮齿动物的记忆力,可用于研究阿尔茨海默型老年性痴呆(SDAT)。 | |||
T19333 |
Gadoteridol
ProHance,SQ-32692,钆特醇,Gd-HP-DO3A |
Others | Others |
Gadoteridol (Gd-HP-DO3A) 是含钆基的 MRI 造影剂,可用于中枢神经系统成像。 | |||
T26778L |
Besipirdine hydrochloride
HP 749 hydrochloride,Besipirdine hydrochloride(119257-34-0 Free base) |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Besipirdine hydrochloride 是一种非受体依赖性拟胆碱化合物,具有α-肾上腺素能活性和心血管活性。Besipirdine hydrochloride 抑制电压依赖性钠钾通道,抑制生物胺的摄取。Besipirdine hydrochloride 可减少大鼠的时间表诱导的烦渴,增强中枢神经系统中的胆碱能和肾上腺素能神经传递。 | |||
T32125 |
Hyperphyllin
HP |
||
Hyperphyllin specifically mimics the branch defects of AMP1, including plastid reduction and expansion and proliferation of the branch meristem. | |||
T30590 |
Brocrinat
HP 522 |
||
Brocrinat (HP 522) is an active diuretic with at least one site of action in the medulla oblongata branch of the Henle loop. | |||
T28160 |
Nerispirdine HCl
HP-184,HP 184,Nerispirdine hydrochloride,HP184 |
||
Nerispirdine is a acetylcholine release enhancer, sodium channel blocker and K(V) 2.1 channel blocker. Nerispirdine inhibits voltage-dependent Na(+) channel currents recorded from human SH-SY5Y cells with an IC(50) of 11.9 micromol/L when measured from a | |||
T27563 |
Hydroxypropyl-beta-cyclodextrin
HP-beta-CyD,VTS-270,HP-beta-CD,Hydroxypropyl-beta-cyclodextri,THPB,HPbCD |
||
Hydroxypropyl-beta-cyclodextrin, also known as Hydroxypropyl-beta-cyclodextrin; THPB; HP-beta-CD; HPbCD; HP-beta-CyD; VTS-270; HPbetaCD; HPbetaCyD, is a drug candidate potentially for the treatment of Niemann-Pick type C diseases. In April 2009, hydroxypr | |||
T34223 |
Quilostigmine
HP 290,NXX 066,NXX-066 |
||
Quilostigmine is a cholinergic. | |||
TP1939L1 |
RVD-Hpα acetate(1193362-76-3 free base)
|
Cannabinoid Receptor | GPCR/G Protein |
RVD-Hpα acetate(1193362-76-3 free base) 是人血加压素的 N 末端延伸形式,可作为选择性 CB1 受体激动剂。增加体外表达 CB1 受体的细胞中的细胞内 Ca2+ 水平。也是高亲和力 CB2 正变构调节剂 (Ki = 50 nM)。 | |||
T34031 |
Phosphazide
AZT-5'-Phosphonate,AZT-5'-H2PO3,Nicavir,AZT-HP |
||
Phosphazide is a zidovudine prodrug. | |||
T32018 |
Guanoxyfen sulfate
CI-515,C.I. 515,HP 1598,CN-34,799-5A,CI 515 |
||
Guanoxyfen sulfate is a bio-active chemical. | |||
T27635 |
Isoxepac
伊索克酸,Olopatadine USP Related Compound C |
Others | Others |
Isoxepac (Olopatadine USP Related Compound C) 是非甾体抗炎剂,显示出抗炎、镇痛和解热活性,已在多种动物模型中进行了相关研究。 | |||
TP2340 |
Hemoregulatory peptide 5b
hp 5B,Pglu-glu-asp-cys-lys-OH,Peedck,Glp-glu-asp-cys-lys-OH,SP1 Pentapeptide |
||
Hemoregulatory peptide 5b is a synthetic analog of granulocyte chalone which initially identified in extracts of rodent bone marrow and human leukocytes. Monomer inhibits both formations of GM-CFC colonies and cytotoxic drug-induced recruitment of murine | |||
T75936 | RVD-Hpα TFA | ||
RVD-Hpα TFA is the N-terminally extended form of human hemopressin that acts as a selectiveCB1receptoragonist. RVD-Hpα TFA increases intracellular Ca2+levels in cells expressingCB1receptors in vitro. RVD-Hpα TFA also high affinityCB2positive allosteric modulator (Ki=50 nM). | |||
T61329 |
HP1142
|
||
HP1142 is a highly effective and specific inhibitor targeting the FLT3 receptor tyrosine kinase, with a particular affinity for its mutant variant FLT3/ITD. It exhibits a benzoimidazole scaffold-based structure, making it a promising compound for investigating and studying the FLT3/ITD mutation in the context of leukemia research [1]. | |||
T78073 |
HP210
|
Glucocorticoid Receptor | Endocrinology/Hormones |
HP210是一种选择性糖皮质激素受体调节剂(SGRM),可以抑制IL-1β和IL-6的mRNA表达,有望用于研究炎症相关疾病。 | |||
T83865 |
HP661
|
||
HP661是一种针对线粒体复合物I(也称为NADH脱氢酶)的抑制剂,对复合物I具有选择性,以1 µM的浓度抑制其77.6%,而对复合物III抑制率为28.1%,对复合物II和IV则无抑制作用。HP661特异性降低具有高水平氧化磷酸化作用的人类肺癌细胞H460、NCI H441及对trametinib耐药的A549细胞的生存能力(IC50分别为10.6、29.7和15.1 nM),相较于氧化磷酸化水平低的NCI H358人类肺癌细胞(IC50 >10,000 nM)以及非癌性人类胰腺正常上皮细胞(HPNE)和MRC-5人类胎肺成纤维细胞(两者的IC50均>10,000 nM)。当以每天两次,每次30 mg/kg的剂量给药时,HP661在H460小鼠异种移植模型中减少肿瘤体积,并对trametinib引导的肿瘤生长减少产生加成效应。 | |||
T64182 |
HP590
|
||
HP590 是一种新型的、强效的、口服具有活力的 STAT3 抑制剂 (STAT3 荧光素酶活性:IC50=27.8 nM; ATP 抑制:IC50=24.7 nM)。HP590 具有抗胃癌细胞增殖的作用,能够诱导细胞凋亡。 | |||
T61758 |
HP1328
|
||
HP1328 is a highly effective inhibitor of FLT3 receptor tyrosine kinase with a specific focus on FLT3/ITD mutation. It belongs to the benzoimidazole scaffold-based compound family. Significantly reducing the leukemia burden, HP1328 effectively extends the survival of mice afflicted with FLT3/ITD leukemia [1]. | |||
T71279 |
BPR1K653
|
||
BPR1K653 is a potent Aurora kinase inhibitor with potential anticancder activity. BPR1K653 specifically inhibited the activity of Aurora-A and Aurora-B kinase at low nano-molar concentrations in vitro. BPR1K653 was potent in targeting a variety of cancer cell lines regardless of the tissue origin, p53 status, or expression of MDR1. At the cellular level, BPR1K653 induced endo-replication and subsequent apoptosis in both MDR1-negative and MDR1-positive cancer cells. Importantly, it showed potent ... | |||
T62253 | S-HP210 | ||
S-HP210 是一种选择性的、有效的糖皮质激素受体 (GR) 调节剂,能够抑制 NF-κB 转录 (IC50: 1.92 μM)。S-HP210 对于 LPS 诱导的多种促炎基因(如 IL-1β、IL-6 和 COX-2)的转录具有抑制作用。S-HP210 在有效剂量下对小鼠成纤维细胞 3T3 没有毒性。 | |||
T62252 |
R-HP210
|
||
R-HP210 能够抑制 LPS 诱导的多种促炎基因(IL-1β、IL-6 和 COX-2)的转录。R-HP210 对 NF-κB 介导的栓系反式抑制功能的 IC50 值为 3.80 μM。R-HP210 不诱导糖皮质激素 (GCs) 的反式激活功能。 | |||
T22021 |
ACHP
IKK-2 Inhibitor VIII |
IκB/IKK | NF-κB |
ACHP(IKK-2 Inhibitor VIII) 是一种新型具有选择性和高效性的 IKK 抑制剂,对IKK-α和IKK-β 具有抑制作用。ACHP 具有抗 HIV-1 活性,通过抑制 NF-κB 激活来抑制 HIV-1 长末端重复序列 (LTR) 驱动的基因表达,抑制 TNF-α 诱导的 NF-κB (p65)募集到 HIV-1 LTR。 | |||
T17909 |
(S,R,S)-AHPC-PEG3-N3
VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12 |
Others; E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 3 个单元 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T17924 |
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
VH032-PEG2-NH2 hydrochloride,VHL Ligand-Linker Conjugates 3 hydrochloride,E3 ligase Ligand-Linker Conjugates 6 |
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 2 个单元 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物,可用于 PROTAC 的合成分子。 | |||
T10809L |
CHPG hydrochloride
CHPG hydrochloride(170846-74-9 Free base) |
ERK; NF-κB; GluR | MAPK; Neuroscience; NF-κB |
CHPG hydrochloride 是 mGluR5 的选择性激动剂。 | |||
T28410 |
PHPS1
PHPS-1,PHPS 1 |
Phosphatase | Metabolism |
PHPS1 是 Shp2的选择性抑制剂,对 Shp2,Shp2-R362K,Shp1,PTP1B 和 PTP1B-Q 的 Ki 分别为 0.73,5.8,10.7,5.8 和 0.47 μM。 | |||
T18675 |
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride
VH032 amide-PEG2-amine,VH032-PEG2-NH2 dihydrochloride,(S,R,S)-AHPC-PEG2-NH2二盐酸盐,VH032-linker 12 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 2 个单元 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物,可用于 PROTAC 分子的合成。 | |||
T1804 |
HPGDS inhibitor 1
HPGDS-inhibitor-1 |
PGE Synthase | Immunology/Inflammation |
HPGDS inhibitor 1 是口服具有活性的HPGDS 选择性抑制剂,在酶和细胞分析中的IC50值分别为 0.6 nM 和 32 nM,但对 L-PGDS、mPGES、COX-1、COX-2 、5-LOX 无抑制作用。 | |||
T8412 |
(S,R,S)-AHPC
VH032-NH2,MDK7526,VHL ligand 1 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC (VH032-NH2) 是一种 VH032-based VHL ligand,可用于募集 von Hippel-Lindau (VHL)蛋白。它能够利用 linker 与靶蛋白配体连接,得到 PROTAC 分子。 | |||
T18640 |
(S,R,S)-AHPC-C4-NH2 hydrochloride
VH032-C4-NH2 hydrochloride,E3 ligase Ligand-Linker Conjugates 28,VHL Ligand-Linker Conjugates 13 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-C4-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 28) 是一种合成的 E3 连接酶配体- linker 偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 linker。 | |||
T9777 |
THP104c
|
Mitochondrial Metabolism | Metabolism |
THP104c 是有效的线粒体分裂抑制剂。 | |||
T77668 |
hPL-IN-1
|
Others | Others |
hPL-IN-1 是一种有效的可逆胰脂肪酶 (PL) 抑制剂 (IC50=1.86 μM),可用于研究与肥胖相关的疾病。 | |||
T17920 |
(S,R,S)-AHPC-PEG1-N3
VHL Ligand-Linker Conjugates 9,VH032-PEG1-N3,E3 ligase Ligand-Linker Conjugates 3 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) 是 E3 连接酶配体和linker 连接得到的 偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 1 个单元 PEG linker。 | |||
T19955 |
Biotin-HPDP
Pyridyldisulfide-biotin,Pyridyldithiol-biotin |
Others | Others |
Biotin-HPDP (Pyridyldithiol-biotin) 是一种巯基反应性生物素化试剂。 | |||
T17921 |
(S,R,S)-AHPC-PEG4-N3
VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4 |
Others; PROTAC Linker | Others; PROTAC |
(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both commonly employed in PROTAC technology. | |||
T18912 |
ADHP
10-乙酰基-3,7-二羟基吩嗪,10-Acetyl-3,7-dihydroxyphenoxazine |
Others | Others |
ADHP (10-Acetyl-3,7-dihydroxyphenoxazine) 是荧光过氧化物酶底物,其λex=530 nm,λem=590 nm。 | |||
T10237 |
ACHP Hydrochloride
IKK-2 Inhibitor VIII |
IκB/IKK | NF-κB |
ACHP Hydrochloride (IKK-2 Inhibitor VIII) 是选择性的IKK-β抑制剂 (IC50=5.8 nM)。 | |||
T2430 |
HPOB
|
Apoptosis; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
HPOB 是一种高选择性HDAC6抑制剂,IC50为 56 nM,其选择性是其他 HDAC 的 30 倍以上。它提高 DNA 损伤抗癌药物在转化细胞中的有效性。 | |||
T4658 |
MHP
Methyl caprooyl tyrosinate |
S1P Receptor | GPCR/G Protein |
MHP (Methyl caprooyl tyrosinate) 是一种鞘氨醇激酶 (SPHK1) 激活剂,可显著增加 CAMP mRNA 和蛋白水平,还可增强抗微生物防御能力和先天免疫力。 | |||
T2681 |
hPGDS-IN-1
|
PGE Synthase | Immunology/Inflammation |
hPGDS-IN-1是 hPGDS 抑制剂,使用荧光偏振检测或通过 EIA 法测得的 IC50值为12 nM。 | |||
T38948 |
MS-PEG4-THP
|
PROTAC Linker | PROTAC |
MS-PEG4-THP 是PEG 类PROTAC linker,可用于合成 PROTAC 分子。 | |||
T40028 |
(S,R,S)-AHPC
|
Ligand for E3 Ligase | PROTAC |
(S,R,S)-AHPC 是一种 VHL 配体,用于募集 VHL 蛋白。 | |||
T13671 |
(S,R,S)-AHPC-Me hydrochloride
VHL ligand 2 hydrochloride,E3 ligase Ligand 1 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein. | |||
T6967 |
RHPS4
RHPS 4 methosulfate,NSC714187 |
Apoptosis; Telomerase | Apoptosis; DNA Damage/DNA Repair |
RHPS4 (RHPS 4 methosulfate) 是 DNA 损伤诱导剂,是一种有效的亚微摩尔端粒酶抑制剂,IC50为0.33 μM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4797 |
DEHP
Bis(2-ethylhexyl) phthalate,邻苯二甲酸二(2-乙基己)酯 |
Others; Endogenous Metabolite | Metabolism; Others |
DEHP (Bis(2-ethylhexyl) phthalate) 是内源性代谢产物的一种。 | |||
TN6684 | Cyclo(Tyr-Hpro) | ||
Cyclo(Tyr-Hpro) 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6684,CAS号为 813461-21-1。 | |||
T36560 |
(±)9-HpODE
|
||
(±)9-HpODE is a racemic mixture of the fatty acid hydroperoxide product (9(S)-HpODE) formed from lipoxygenase action on linoleic acid. It shows antimicrobial activity against various fungal and bacterial pathogens and thus may play a role in plant defense. In mammalian species, monocyte-induced oxidization of LDL generates significant amounts of esterified 9-HpODE, which is rapidly reduced to 9-HODE. | |||
TN3118 |
5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone (DHPA)
|
Others | Others |
5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone (DHPA) is a pancreatic lipase inhibitor, it shows antihyperlipidemic activity. | |||
TN7019 |
DNHP
|
||
DNHP is a natural product. | |||
TN6429 |
Cyclo(Phe-Hpro)
|
||
Cyclo(Phe-Hpro) 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6429,CAS号为 1016899-94-7。 | |||
TN6680 |
Cyclo(Hpro-Leu)
|
||
Cyclo(Hpro-Leu) 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6680,CAS号为 1016899-93-6。 | |||
T74193 |
(R)-IDHP
|
||
(R)-IDHP为IDHP异构体,属于丹参代谢物。该化合物能通过抑制血管平滑肌细胞电压依赖性钙通道与受体操作钙通道的Ca2+释放和Ca2+内流,发挥血管松弛作用,适用于心脑血管疾病研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05372 |
FGL1 Protein, Human, Recombinant (His)
LFIRE-1,LFIRE1,HFREP1,HP-041,fibrinogen-like 1 |
Human | Baculovirus Insect Cells |
FGL1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number is Q08830. | |||
TMPJ-00729 |
Haptoglobin Protein, Human, Recombinant (N-His)
Haptoglobin,HP,Zonulin |
Human | E. coli |
Haptoglobin Protein, Human, Recombinant (N-His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35 KDa and the accession number is P00738. | |||
TMPJ-00730 |
Haptoglobin Protein, Human, Recombinant (C-His)
Zonulin,HP,Haptoglobin |
Human | HEK293 Cells |
Haptoglobin Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16 and 40-75 KDa and the accession number is P00738. | |||
TMPY-05734 |
FGL1 Protein, Human, Recombinant (hFc)
HFREP1,LFIRE1,LFIRE-1,fibrinogen-like 1,HP-041 |
Human | HEK293 Cells |
FGL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.7 kDa and the accession number is Q08830. | |||
TMPY-05464 |
FGL1 Protein, Human, Recombinant (mFc)
HP-041,LFIRE-1,HFREP1,fibrinogen-like 1,LFIRE1 |
Human | HEK293 Cells |
FGL1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.4 kDa and the accession number is Q08830. | |||
TMPY-05778 |
FGL1 Protein, Human, Recombinant (His & Avi)
HFREP1,LFIRE1,LFIRE-1,HP-041,fibrinogen-like 1 |
Human | Baculovirus Insect Cells |
FGL1 Protein, Human, Recombinant (His & Avi) is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 37.27 kDa and the accession number is Q08830. | |||
TMPH-00798 |
HP-0175 Protein, Helicobacter pylori, Recombinant (GST)
|
Helicobacter pylori | E. coli |
N/A. HP-0175 Protein, Helicobacter pylori, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 58.8 kDa and the accession number is P56112. | |||
TMPY-01870 |
IL-9 Protein, Human, Recombinant (His)
P40,interleukin 9,HP40,白细胞介素,IL-9,白介素 |
Human | Baculovirus Insect Cells |
IL-9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is P15248. | |||
TMPJ-00195 |
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
LFIRE-1,FGL1,Fibrinogen-like protein 1,Hepassocin,HP |
Cynomolgus | HEK293 Cells |
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 36 KDa and the accession number is A0A2K5X990. | |||
TMPJ-00197 |
FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
FGL1,HP-041,Fibrinogen-like protein 1,LFIRE-1,Hepas... |
Human | HEK293 Cells |
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major imm... | |||
TMPJ-00198 |
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
HFREP-1,HP-041,Fibrinogen-like protein 1,Hepassocin... |
Human | HEK293 Cells |
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 35 KDa and the accession number is Q08830. | |||
TMPK-00204 |
FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
Hepassocin,Lag3 ligand,HP-041,LFIRE-1,HFREP1,FGL1,H... |
Human | HEK293 Cells |
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3. | |||
TMPY-00346 |
DEFA3 Protein, Human, Recombinant (hFc)
Defensin α3/DEFA3,defensin alpha 3,HP-3,HNP-3,DEF3,... |
Human | HEK293 Cells |
DEFA3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.8 kDa and the accession number is P59666. | |||
TMPH-00797 |
HopQ Protein, Helicobacter pylori Hp M6, Recombinant (His & Myc)
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Helicobacter pylori Hp M6 | E. coli |
HopQ Protein, Helicobacter pylori Hp M6, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00794 |
Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)
napA,DNA protection during starvation protein,Bacterioferrit... |
Helicobacter pylori | E. coli |
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role... | |||
TMPH-02503 |
DEFA1 Protein, Mouse, Recombinant (GST & His)
HP-1,HNP-1,Defensin, alpha 1,DEFA1,DEFA2,MRS,Neutro... |
Mouse | E. coli |
Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 34.1 kDa and the accession number is P11477. | |||
TMPH-01772 |
DEFA1 Protein, Human, Recombinant (GST)
MRS,HP1,HP-1,DEFA1,DEF1,Defensin, alpha 1,... |
Human | E. coli |
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665. | |||
TMPH-02997 |
Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)
Neutrophil-activating protein A,NAP A,HP-NAP,Bacter... |
Mycobacterium smegmatis | E. coli |
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage. Dps Protein, Mycobacterium sme... | |||
TMPY-01032 |
CD299 Protein, Human, Recombinant (hFc)
LSIGN,CLEC4M,C-type lectin domain family 4 member M,MGC47866... |
Human | HEK293 Cells |
CD299 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q9H2X3-1. | |||
TMPY-03261 |
CNPY2 Protein, Human, Recombinant (His)
canopy FGF signaling regulator 2,HP10390,ZSIG9,MSAP... |
Human | HEK293 Cells |
CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light chain. It is expressed in different tissues, including brain. Overexpression of CNPY2 enhanced the motility of glioma cells measured in matrigel invasion chambers and using a scratch assay. Downregulation of CNPY2 by RNA interference significantly decreased glioma cell migration and... | |||
TMPK-00568 |
IL-9 Protein, Cynomolgus, Recombinant (His)
P40,HP40,IL-9,T-cell growth factor P40,Interleukin-... |
Cynomolgus | HEK293 Cells |
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Cynomolgu... | |||
TMPY-00129 |
CLEC2B Protein, Human, Recombinant (hFc)
C-type lectin domain family 2 member B,CLECSF2,AICL,HP |
Human | HEK293 Cells |
CLEC2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is AAH05254.1. | |||
TMPK-00025 |
IL-9 Protein, Human, Recombinant (hFc)
HP40,Cytokine P40,白细胞介素,Interleukin-9,白介素,P40,T-cel... |
Human | HEK293 Cells |
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Human, Re... | |||
TMPK-00026 |
IL-9 Protein, Mouse, Recombinant (hFc)
P40,IL-9,Interleukin-9,Cytokine P40,T-cell growth factor P40... |
Mouse | HEK293 Cells |
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Mouse, Re... | |||
TMPJ-01330 |
CD299 Protein, Human, Recombinant (His & Flag)
DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fami... |
Human | HEK293 Cells |
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso... | |||
TMPY-04231 |
CD299 Protein, Human, Recombinant
HP10347,CLEC4M,DCSIGNR,MGC47866,L-SIGN,C-type lecti... |
Human | HEK293 Cells |
CD299 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 37 kDa and the accession number is Q9H2X3-1. | |||
TMPY-00979 |
HRG/HPRG Protein, Human, Recombinant (His)
THPH11,histidine-rich glycoprotein,HRGP,HP... |
Human | HEK293 Cells |
HRG/HPRG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P04196. | |||
TMPH-01831 |
Human Papilloma Virus type 16 (HPV 16) Protein E4 (His & Myc)
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HPV 16 | E. coli |
Human Papilloma Virus type 16 (HPV 16) Protein E4 (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.5 kDa and the accession number is P06922. | |||
TMPH-01843 |
Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His)
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HPIV-4b | E. coli |
Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 68.5 ... | |||
TMPH-01826 |
Human Papilloma Virus type 11 (HPV 11) Protein E4 (His)
|
HPV 11 | E. coli |
Human Papilloma Virus type 11 (HPV 11) Protein E4 (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.0 kDa and the accession number is P04016. | |||
TMPY-05400 |
Human Papilloma Virus type 11 (HPV 11) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 11 (HPV 11) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 55 kDa. | |||
TMPH-01525 |
CMAHP Protein, Human, Recombinant (His & Myc)
CMAHP,Inactive cytidine monophosphate-N-acetylneura... |
Human | E. coli |
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates. However, it may play a role in Wnt signaling. | |||
TMPH-03311 |
HPSE Protein, Rat, Recombinant (His & Myc)
|
Rat | E. coli |
HPSE Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 15.8 kDa and the accession number is Q71RP1. | |||
TMPY-05405 |
Human Papilloma Virus type 35 (HPV 35) L1 Protein-VLP
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HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 35 (HPV 35) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPH-01830 |
Human Papilloma Virus type 16 (HPV 16) Minor capsid Protein L2 (His & SUMO)
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HPV 16 | E. coli |
Human Papilloma Virus type 16 (HPV 16) Minor capsid Protein L2 (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 66.7 kDa and the accession number is P03107. | |||
TMPJ-00938 |
4HPPD Protein, Human, Recombinant (His)
PPD,4HPPD,HPD,4-Hydroxyphenylpyruvate Diox... |
Human | E. coli |
4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in h... | |||
TMPY-05403 |
Human Papilloma Virus type 31 (HPV 31) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 31 (HPV 31) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPJ-01019 |
NHP2L1 Protein, Human, Recombinant (His)
High Mobility Group-Like Nuclear Protein 2 Homolog 1,hSNU13,... |
Human | E. coli |
NHP2-Like Protein 1 (NHP2L1) is a member of the ribosomal protein L7Ae family. NHP2L1 proteinis limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 has been shown to interact with RAD17and PRPF31. The protein undergoes a conformational change upon RNA-binding. NHP2L1 binds to the 5-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly, prior to step I of splicing catalysis. | |||
TMPK-00724 |
HPN Protein, Mouse, Recombinant (His)
Hemopexin,TMPRSS1,Hpxn,HPX,FLJ56652,Hepsin... |
Mouse | HEK293 Cells |
HPN Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.2 kDa and the accession number is O35453-1. | |||
TMPH-01838 |
Human Papilloma Virus type 52 (HPV 52) Protein E7 (His & SUMO)
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HPV 52 | E. coli |
Human Papilloma Virus type 52 (HPV 52) Protein E7 (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.0 kDa and the accession number is P36831. | |||
TMPH-01842 |
Human parainfluenza 2 virus (HPIV-2) Hemagglutinin-neuraminidase Protein (His)
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HPIV-2 | E. coli |
Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.; Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins. Human parainfluenza 2 virus (HPIV-2) Hemagglutinin-neuraminidase Protein (His) is expressed in E. coli expression sys... | |||
TMPY-05401 |
Human Papilloma Virus type 16 (HPV 16) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 16 (HPV 16) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPK-01466 |
HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi)
Human papillomavirus type 16,E6,HPV16 |
Human | HEK293 Cells |
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer. | |||
TMPH-01828 |
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E2 (His & Myc)
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HPV 11 | E. coli |
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E2 (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.2 kDa and the accession number is P04015. | |||
TMPY-04788 |
HRG/HPRG Protein, Rat, Recombinant (His)
histidine-rich glycoprotein |
Rat | HEK293 Cells |
HRG/HPRG Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.6 kDa and the accession number is A6JS43. | |||
TMPH-00709 |
DAHP synthase Protein, E. coli, Recombinant (His)
Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive,P... |
E. coli | E. coli |
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). DAHP synthase Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.8 kDa and the accession number is P00887. | |||
TMPY-02002 |
PHPT1 Protein, Human, Recombinant (His)
phosphohistidine phosphatase 1,CGI-202,HSPC141,HEL-S-132P,P<... |
Human | E. coli |
PHPT1, also known as 14 kDa phosphohistidine phosphatase, phosphohistidine phosphatase 1, protein janus-A homolog, PHP14, is a cytoplasm protein which belongs to the janus family. PHPT1 / PHP14 is expressed abundantly in heart and skeletal muscle. Phosphatases are a diverse group of enzymes that regulate numerous cellular processes. Much of what is known relates to the tyrosine, threonine, and serine phosphatases, whereas the histidine phosphatases have not been studied as much. Protein histidin... | |||
TMPY-04077 |
HPGDS/PGD2 Protein, Human, Recombinant (His)
hematopoietic prostaglandin D synthase,PGD2,GSTS1-1,GSTS1,PG... |
Human | E. coli |
HPGDS/PGD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.2 kDa and the accession number is O60760. | |||
TMPH-01841 |
Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His)
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HPIV-1 | E. coli |
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. T... | |||
TMPH-01861 |
LHPP Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency. LHPP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.2 kDa and the accession number is Q9H008. | |||
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