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Search Results for " fgfr-3 "
Targets Recommended: EGFR FGFR

23

抑制剂 & 化合物

1

天然产物

71

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T3466 FIIN-3

EGFR; FGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
FIIN-3FGFR 的不可逆抑制剂,对FGFR1、FGFR2、FGFR3FGFR4的IC50值分别为13.1、21、31.4和35.3 nM。
T4425 JK-P3

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导,也可阻碍内皮单层细胞迁移和血管生成,影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。
T2341 KW-2449

KW2449

Apoptosis; FGFR; FLT; JAK; Bcr-Abl; Src; c-Kit; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
KW-2449是一种多靶点激酶抑制剂,对FLT3,ABL,ABLT315I 和极光激酶的IC50值分别为6.6,14,4 和 48 nM。
T2638 Gandotinib

LY2784544

VEGFR; FGFR; FLT; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Gandotinib (LY2784544) 是一种JAK2抑制剂,IC50为 3 nM。它也抑制FLT3、FLT4、FGFR2、TYK2 和 TRKB,IC50分别为 4、25、32、44 和 95 nM。
T61660 FGFR-IN-3

FGFR-IN-3 (compound 6) is a highly potent and orally active modulator of FGFR (fibroblast growth factor receptor). It has the ability to penetrate the blood-brain barrier (BBB). Additionally, FGFR-IN-3 exhibits significant neuroprotective properties. Therefore, it holds potential for research on neurodegenerative diseases [1].
T2358 ENMD-2076

Apoptosis; VEGFR; FGFR; FLT; c-RET; PDGFR; Src; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
ENMD2076是一种多靶点激酶抑制剂,抑制Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3FGFR1、FGFR2、Src、PDGFRα的IC50值分别为1.86、14、58.2、15.9、92.7、70.8、20.2 and 56.4 nM。
T6479 Dovitinib lactate hydrate

Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib lactate hydrate (TKI258) 是一种多靶点的酪氨酸激酶抑制剂,抑制 FLT3,c-Kit,FGFR1/3,VEGFR1/2/3和 PDGFRα/β的 IC50值分别为 1,2,8/9,10/13/8,27/210 nM。
T7104 Dovitinib lactate

CHIR-258 lactate,多韦替尼乳酸盐,TKI-258 lactate

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib lactate (TKI-258 lactate) 是一种多靶点的酪氨酸激酶抑制剂,抑制FLT3,c-Kit,FGFR1/3,VEGFR1/2/3和PDGFRα/β的IC50值分别为 1,2,8/9,10/13/8,27/210 nM。
T6289 Dovitinib

TKI258,多韦替尼,CHIR-258,度维替尼

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib (CHIR-258) 是一种口服有效的、多靶点的酪氨酸激酶 (RTK) 抑制剂,具有抗肿瘤作用。
T6028 PF 477736

PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

c-Fms; VEGFR; FGFR; FLT; c-RET; Chk; CDK; Src; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
PF 477736 (PF-736,PF-00477736) 是一种特异性、有效且具有 ATP 竞争性的 Chk1 抑制剂,Ki 值为0.49 nM。它也是Chk2抑制剂,Ki 值为 47 nM。它还抑制VEGFR2、Fms、Yes、Aurora-A、FGFR3、Flt3和Ret。
T1975 Infigratinib

BGJ-398,NVP-BGJ398

Apoptosis; FGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Infigratinib (NVP-BGJ398) 是一种 FGFR 家族抑制剂,抑制 FGFR1,FGFR2,FGFR3FGFR4的 IC50分别为 0.9 nM,1.4 nM,1 nM,60 nM。
T5473 ASP5878

ASP-5878

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
ASP5878 是一种 FGFR 1 (IC50:0.47 nM)、FGFR 2 (IC50:0.6 nM)、FGFR 3 (IC50:0.74 nM)、和 FGFR 4 (IC50:3.5 nM)的抑制剂,具有口服活性,具有潜在的抗肿瘤作用。
T6036 Brivanib

BMS-540215,布立尼布

EGFR; VEGFR; FGFR; Autophagy Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Brivanib (BMS-540215) 是一种针对 VEGFR2 的 ATP 竞争性抑制剂,IC50 为 25 nM。它对 VEGFR-1 和 FGFR-1 具有中等效力,对 VEGFR2 的选择性是对 PDGFR-β 的 240 倍。
T5044 Futibatinib

TAS120,FGFR-IN-1

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Futibatinib (FGFR-IN-1) 是口服具有活力的、选择性强的、高生物利用度的、不可逆的 FGFR 抑制剂。它抑制突变型和野生型 FGFR2,且 IC50相似(wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM)。
T16781 Rogaratinib

BAY1163877

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Rogaratinib (BAY1163877) 选择性抑制成纤维细胞生长因子受体。
T1948 AZD4547

VEGFR; FGFR Angiogenesis; Tyrosine Kinase/Adaptors
AZD4547 是FGFR 家族抑制剂,能够作用于FGFR1 (IC50:0.2 nM),FGFR2 (IC50:2.5 nM),FGFR3 (IC50:1.8 nM) 和FGFR4 (IC50:165 nM)。
T6836 FIIN-2

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FIIN2 是一种 FGFR 的不可逆抑制剂,能够抑制 FGFR1 (IC50:3.1 nM),FGFR2 (IC50:4.3 nM),FGFR3 (IC50:27 nM) 和 FGFR4 (IC50:45 nM)。
T3726 Erdafitinib

厄达替尼,JNJ-42756493

Apoptosis; FGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Erdafitinib (JNJ-42756493) 是一种喹喔啉衍生物,是一种具有口服活性的FGFR 家族抑制剂,抑制FGFR1/2/3/4活性的IC50分别为1.2、 2.5、3.0和5.7 nM。
T62652 CPL304110

CPL304110 是一种口服具有活力的、选择性的、有效的成纤维细胞生长因子受体 FGFR (1-3) 的抑制剂,能够作用于 FGFR1 (IC50: 0.75 nM)、 FGFR2 (IC50: 0.5 nM)、FGFR3 (IC50: 3.05 nM) 。
T82404 FGFR3-IN-7

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FGFR3-IN-7为高选择性FGFR3抑制剂,显示出小于350 nM 的IC50效价,主要用于癌症相关研究。
T82405 FGFR3-IN-6

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FGFR3-IN-6为FGFR3选择性抑制剂,具有低于350 nM 的IC50,适用于癌症研究领域。
T63967 Multi-kinase-IN-2

Multi-kinase-IN-2 是口服具有活力的血管激酶 (angiokinase) 抑制剂。Multi-kinase-IN-2 能够显著抑制血管激酶的活性,如 VEGFR-1/2/3、PDGFRα/β、FGFR-1、LYN 和 c-KIT 激酶。Multi-kinase-IN-2 能够明显减弱 AKT 和 ERK 蛋白的磷酸化,并可诱导细胞凋亡 (apoptosis),具有抗癌作用。
T3512 S49076 HCl

S-49076 Hydrochloride

FGFR; c-Met/HGFR; TAM Receptor Angiogenesis; Tyrosine Kinase/Adaptors
S49076 HCl (S-49076 Hydrochloride) 是 MET、AXL/MER 和 FGFR1/2/3 的有效抑制剂。S49076 HCl 在体外和体内有效阻断 MET、AXL 和 FGFR 的细胞磷酸化并抑制下游信号传导。在细胞模型中,S49076 HCl (S-49076 Hydrochloride) 抑制 MET 和 FGFR2 依赖性胃癌细胞的增殖,阻断 MET 驱动的肺癌细胞迁移,并抑制表达 FGFR1/2 和 AXL 的肝癌细胞的集落形成。在肿瘤异种移植模型中,建立了口服 S49076 HCl (S-49076 Hydrochloride) 后 MET 和 FGFR2 抑制的良好药代动力学/药效学关系,并与对肿瘤生长的影响密切相关。

化合物

FIIN-3
Cat.No: T3466
Synonym:
Target: EGFR, FGFR
JK-P3
Cat.No: T4425
Synonym:
Target: VEGFR
KW-2449
Cat.No: T2341
Synonym: KW2449
Target: Apoptosis, FGFR, FLT, JAK, Bcr-Abl, Src, c-Kit, Aurora Kinase
Gandotinib
Cat.No: T2638
Synonym: LY2784544
Target: VEGFR, FGFR, FLT, JAK
FGFR-IN-3
Cat.No: T61660
Synonym:
Target:
ENMD-2076
Cat.No: T2358
Synonym:
Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase
Dovitinib lactate hydrate
Cat.No: T6479
Synonym: Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Dovitinib lactate
Cat.No: T7104
Synonym: CHIR-258 lactate,多韦替尼乳酸盐,TKI-258 lactate
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Dovitinib
Cat.No: T6289
Synonym: TKI258,多韦替尼,CHIR-258,度维替尼
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
PF 477736
Cat.No: T6028
Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736
Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase
Infigratinib
Cat.No: T1975
Synonym: BGJ-398,NVP-BGJ398
Target: Apoptosis, FGFR
ASP5878
Cat.No: T5473
Synonym: ASP-5878
Target: FGFR
Brivanib
Cat.No: T6036
Synonym: BMS-540215,布立尼布
Target: EGFR, VEGFR, FGFR, Autophagy
Futibatinib
Cat.No: T5044
Synonym: TAS120,FGFR-IN-1
Target: FGFR
Rogaratinib
Cat.No: T16781
Synonym: BAY1163877
Target: FGFR
AZD4547
Cat.No: T1948
Synonym:
Target: VEGFR, FGFR
FIIN-2
Cat.No: T6836
Synonym:
Target: FGFR
Erdafitinib
Cat.No: T3726
Synonym: 厄达替尼,JNJ-42756493
Target: Apoptosis, FGFR
CPL304110
Cat.No: T62652
Synonym:
Target:
FGFR3-IN-7
Cat.No: T82404
Synonym:
Target: FGFR
FGFR3-IN-6
Cat.No: T82405
Synonym:
Target: FGFR
Multi-kinase-IN-2
Cat.No: T63967
Synonym:
Target:
S49076 HCl
Cat.No: T3512
Synonym: S-49076 Hydrochloride
Target: FGFR, c-Met/HGFR, TAM Receptor
Cat. No. Product Name Target Signaling Pathways
T2S0007 Ferulic acid sodium

阿魏酸钠,阿魏酸钠;3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate

FGFR; Reactive Oxygen Species; 5-HT Receptor; Endogenous Metabolite Angiogenesis; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
Ferulic acid sodium (Sodium ferulic) 是新型的成纤维细胞生长因子受体 1 (FGFR1) 抑制剂。它对于FGFR1和FGFR2的IC50分别为 3.78 and 12.5 μM。

天然产物

Ferulic acid sodium
Cat.No: T2S0007
Synonym: 阿魏酸钠,阿魏酸钠;3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate
Target: FGFR, Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite
Cat. No. Product Name Species Expression System
TMPY-00973 FGFR3 Protein, Mouse, Recombinant (His & hFc)

FR3,Fgfr-3,Flg-2,CD3...

Mouse HEK293 Cells
FGFR3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q7TSI8.
TMPY-01208 FGFR3 Protein, Mouse, Recombinant (His)

fibroblast growth factor receptor 3,Mfr3,H...

Mouse HEK293 Cells
FGFR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is Q7TSI8.
TMPK-00390 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

FGFR3,JTK4,ACH,FGF R3,FGFR

Human HEK293 Cells
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.
TMPK-00388 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)

HSFGFR3EX,FGF R3,ACH,CD3...

Human HEK293 Cells
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.
TMPK-00385 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)

FGFR3,EC 2.7.10,FGFR3 β ...

Human HEK293 Cells
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P22607-1.
TMPK-00389 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)

FGFR3,FGFR3 β (IIIb),CD<...

Human HEK293 Cells
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa and the accession number is P22607-2.
TMPK-00386 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

ACH,CD333,EC 2.7.10,FGFR...

Human HEK293 Cells
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
TMPK-00391 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

HSFGFR3EX,FGFR3,FGF R

Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p...
TMPK-00384 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

CD333,EC 2.7.10,JTK4,FGFR

Human HEK293 Cells
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
TMPK-00686 FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)

CEK,CD333,HSFGFR3

Mouse HEK293 Cells
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the accession number is E9QNJ9.
TMPK-00387 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

HSFGFR3EX,FGF R3,EC 2.7.10,CD...

Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p...
TMPJ-00715 FGF-19 Protein, Human, Recombinant (His)

FGF-19,Fibroblast growth factor 19,FGF19

Human E. coli
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile ...
TMPY-06986 FGF-8b Protein, Human, Recombinant

NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-00132 Mesothelin Protein, Human, Recombinant

MPF,SMRP,Mesothelin

Human HEK293 Cells
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His)

MER6,CD47 molecule,IAP,OA3

Human HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc)

Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated

CD47 molecule,MER6,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-04683 CD47 Protein, Human, Recombinant

MER6,CD47 molecule,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His)

AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-01897 PRSS3 Protein, Human, Recombinant (His)

PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...

Human HEK293 Cells
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His)

PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...

Human HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His)

NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01180 CD86 Protein, Human, Recombinant (His)

CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72

Human HEK293 Cells
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His)

L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...

Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His)

TRASK,CD318,CUB domain containing protein 1,SIMA1

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00357 HNT/NTM Protein, Human, Recombinant (His)

HNT,NTRI,IGLON2,neurotrimin

Human HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-00480 NCAM1 Protein, Human, Recombinant (His)

neural cell adhesion molecule 1,CD56,MSK39,NCAM

Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc)

CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3....

Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577...
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST)

SET and MYND domain containing 3,ZMYND1,KMT3

Human Baculovirus Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg...
TMPY-03621 EphB2 Protein, Mouse, Recombinant (hFc)

Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<...

Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPJ-01288 KLF6 Protein, Human, Recombinant

CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...

Human E. coli
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul...
TMPY-04386 EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,...

Human Baculovirus Insect Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPY-03149 CDCP1 Protein, Human, Recombinant (mFc)

TRASK,SIMA135,CD318,CUB domain containing ...

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3.
TMPK-00401 FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

ECT1,K-SAM,CD332,CEK3,FGFR

Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
TMPK-00398 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

Fibroblast growth factor receptor 2,CD332,...

Human HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPY-04015 COL9A1 Protein, Human, Recombinant (mFc)

DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage...

Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3.
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)

FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR...

Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
TMPY-05514 RANK/TNFRSF11A Protein, Human, Recombinant (mFc)

OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfamil...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-00276 PLGF/PGF Protein, Human, Recombinant (mFc)

placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2

Human HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

CD357,GITR-D,tumor necrosis factor receptor superfa...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPY-03960 COL9A1 Protein, Human, Recombinant (His)

EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M...

Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3.
TMPY-00715 CD84 Protein, Human, Recombinant (His)

LY9B,mCD84,CD84 molecule,hCD84,SLAMF5

Human HEK293 Cells
CD84 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9UIB8-3.
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc)

sushi domain containing 4,PRO222

Human HEK293 Cells
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path...
TMPY-04216 EphB2 Protein, Mouse, Recombinant (His)

Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH r...

Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3.
TMPJ-00465 PTP1C Protein, Human, Recombinant (His)

HCP,Hematopoietic Cell Protein-Tyrosine Phosphatase,SH-PTP1,...

Human E. coli
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter...
TMPY-02573 IL-17RC Protein, Human, Recombinant (aa 1-454, His)

IL17RL,interleukin 17 receptor C,IL17-RL,UNQ6118/PRO20040/PR...

Human Baculovirus Insect Cells
IL-17RC Protein, Human, Recombinant (aa 1-454, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is Q8NAC3-3.
TMPY-03883 CD47 Protein, Human, Recombinant (hFc)

OA3,CD47 molecule,IAP,MER6

Human HEK293 Cells
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3.
TMPY-01656 VEGF183 Protein, Human, Recombinant

血管内皮生长因子,VEGF165,VPF,VEGF,vascular endothelial growth factor...

Human Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.
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重组蛋白

FGFR3 Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-00973
Species: Mouse
Expression System: HEK293 Cells
FGFR3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01208
Species: Mouse
Expression System: HEK293 Cells
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00390
Species: Human
Expression System: HEK293 Cells
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00388
Species: Human
Expression System: HEK293 Cells
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00385
Species: Human
Expression System: HEK293 Cells
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00389
Species: Human
Expression System: HEK293 Cells
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00386
Species: Human
Expression System: HEK293 Cells
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00391
Species: Human
Expression System: HEK293 Cells
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00384
Species: Human
Expression System: HEK293 Cells
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00686
Species: Mouse
Expression System: HEK293 Cells
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00387
Species: Human
Expression System: HEK293 Cells
FGF-19 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00715
Species: Human
Expression System: E. coli
FGF-8b Protein, Human, Recombinant
Cat.No: TMPY-06986
Species: Human
Expression System: E. coli
Mesothelin Protein, Human, Recombinant
Cat.No: TMPY-00132
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His)
Cat.No: TMPY-04935
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03763
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05191
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant
Cat.No: TMPY-04683
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His)
Cat.No: TMPY-00072
Species: Human
Expression System: HEK293 Cells
PRSS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01897
Species: Human
Expression System: HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01020
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00892
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His)
Cat.No: TMPY-01180
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
Cat.No: TMPY-05748
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04142
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-01099
Species: Human
Expression System: HEK293 Cells
CDCP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04298
Species: Human
Expression System: HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His)
Cat.No: TMPY-00357
Species: Human
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00480
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
Cat.No: TMPK-00447
Species: Human
Expression System: HEK293 Cells
SMYD3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-01268
Species: Human
Expression System: Baculovirus Insect Cells
EphB2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03621
Species: Mouse
Expression System: HEK293 Cells
KLF6 Protein, Human, Recombinant
Cat.No: TMPJ-01288
Species: Human
Expression System: E. coli
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
Cat.No: TMPY-04386
Species: Human
Expression System: Baculovirus Insect Cells
CDCP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03149
Species: Human
Expression System: HEK293 Cells
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00401
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Cat.No: TMPK-00398
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04015
Species: Human
Expression System: HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
Cat.No: TMPJ-00391
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05514
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00276
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06411
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03960
Species: Human
Expression System: HEK293 Cells
CD84 Protein, Human, Recombinant (His)
Cat.No: TMPY-00715
Species: Human
Expression System: HEK293 Cells
SUSD4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03969
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04216
Species: Mouse
Expression System: HEK293 Cells
PTP1C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00465
Species: Human
Expression System: E. coli
IL-17RC Protein, Human, Recombinant (aa 1-454, His)
Cat.No: TMPY-02573
Species: Human
Expression System: Baculovirus Insect Cells
CD47 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03883
Species: Human
Expression System: HEK293 Cells
VEGF183 Protein, Human, Recombinant
Cat.No: TMPY-01656
Species: Human
Expression System: Baculovirus Insect Cells
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