|
TMPY-00772
|
DC-SIGN Protein, Human, Recombinant (hFc)
DC-SIGN,CD209 molecule,CDSIGN,CLEC4L,CD209,MGC12996...
|
Human
|
HEK293
|
|
Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable of binding ICAM-3 on resting T cells in the secondary lymphoid organs, providing the initial contact between these cells during the establishment of cell-mediated immunity. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. It has an importa... |
|
TMPY-04714
|
DC-SIGN Protein, Rhesus, Recombinant (hFc)
CD209 molecule,DC-SIGN,CD209
|
Rhesus
|
HEK293
|
|
Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable of binding ICAM-3 on resting T cells in the secondary lymphoid organs, providing the initial contact between these cells during the establishment of cell-mediated immunity. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. It has an importa... |
|
TMPY-03014
|
Osteoactivin/GPNMB Protein, Mouse, Recombinant (His)
ipd,glycoprotein (transmembrane) nmb,DC-HIL,Dc<...
|
Mouse
|
HEK293
|
|
GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteoclasts, macrophages, dendritic cells, and tumor cells. It is suggested to influence osteoblast maturation, cell adhesion, and migration. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization... |
|
TMPY-04715
|
DC-SIGN Protein, Rhesus, Recombinant (His)
DC-SIGN,CD209,CD209 molecule
|
Rhesus
|
HEK293
|
|
Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable of binding ICAM-3 on resting T cells in the secondary lymphoid organs, providing the initial contact between these cells during the establishment of cell-mediated immunity. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. It has an importa... |
|
TMPK-00255
|
CD209/DC-SIGN Protein, Human, Recombinant (His)
CD209,DC-SIGN,CLEC4L,CD209 molecule,DC-SIG...
|
Human
|
HEK293
|
|
C-type lectin CD209/DC-SIGN and CD209L/L-SIGN proteins are distinct cell adhesion and pathogen recognition receptors that mediate cellular interactions and recognize a wide range of pathogens, including viruses such as SARS, SARS-CoV-2, bacteria, fungi and parasites. Pathogens exploit CD209 family proteins to promote infection and evade the immune recognition system. |
|
TMPY-01032
|
CD299 Protein, Human, Recombinant (hFc)
LSIGN,CLEC4M,C-type lectin domain family 4 member M,MGC47866...
|
Human
|
HEK293
|
|
C-type lectin domain family 4, member M, also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to DC-SIGN, an HIV gp120-binding protein. Though the encoded gene located in the same chromosome, DC-SIGN is expressed solely on dendritic cells, while DC-SIGNR is predominantly found in liver sinusoidal endothelial cells and lymph node, as well as placental endothelium. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called nec... |
|
TMPY-03507
|
PPC-DC Protein, Human, Recombinant (E. coli, His)
coaC,MDS018,PPC-DC,phosphopantothenoylcysteine deca...
|
Human
|
E. coli
|
|
PPC-DC, also known as PPCDC, belongs to the HFCD (homo oligomeric flavin containing Cys decarboxylase) superfamily which takes a part in the biosynthesis of coenzyme A (CoA) from pantothenate (Vitamin B). Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. This process include several steps: the phosphorylation of pantothenate, the conversion of 4’-hosphopantothenate to 4''-phosphopantetheine, the adenylation by pho... |
|
TMPJ-01265
|
PPC-DC Protein, Human, Recombinant (aa 1-204, His)
Phosphopantothenoylcysteine Decarboxylase,PPC-DC,PP...
|
Human
|
E. coli
|
|
Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis ofCoenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cysteine moiety of 4-Phosphopantothenoylcysteine (PPC) to form 4-Phosphopantetheine (PPantSH), this reaction forms part of the biosynthesis of Coenzyme A. The enzyme is a member of the larger family of Cysteine Decarboxylases including the Lantibiotic-Biosynthesizing enzymes EpiD and ... |
|
TMPY-04957
|
PD-L2 Protein, Human, Recombinant (His), Biotinylated
B7DC,Btdc,B7-DC,bA574F11.2,PDL2,p...
|
Human
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPY-05827
|
PD-L2 Protein, Human, Recombinant (mFc)
PDCD1L2,bA574F11.2,Btdc,B7-DC,PD-...
|
Human
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPY-04346
|
PD-L2 Protein, Human, Recombinant (His)
PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7...
|
Human
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPY-00566
|
CCL18 Protein, Human, Recombinant (His)
PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand...
|
Human
|
Yeast
|
|
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a... |
|
TMPY-02718
|
Doublecortin/DCX Protein, Human, Recombinant (aa 45-150, GST)
XLIS,doublecortin,LISX,DBCN,DC,SCLH
|
Human
|
E. coli
|
|
DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it is highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. DCX is a microtubule-associated protein required for initial steps of neuronal dispersion an... |
|
TMPY-01013
|
LAMP3/CD208 Protein, Human, Recombinant (His)
LAMP,DC LAMP,lysosomal associated membrane protein ...
|
Human
|
HEK293
|
|
Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The ... |
|
TMPY-01733
|
SIGNR1 Protein, Mouse, Recombinant (His)
CD209b antigen,DC-SIGNR1,OtB7,SIGNR1,1810030I22Rik,...
|
Mouse
|
HEK293
|
|
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... |
|
TMPY-04231
|
CD299 Protein, Human, Recombinant
HP10347,CLEC4M,DCSIGNR,MGC47866,L-SIGN,C-type lecti...
|
Human
|
HEK293
|
|
C-type lectin domain family 4, member M, also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to DC-SIGN, an HIV gp120-binding protein. Though the encoded gene located in the same chromosome, DC-SIGN is expressed solely on dendritic cells, while DC-SIGNR is predominantly found in liver sinusoidal endothelial cells and lymph node, as well as placental endothelium. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called nec... |
|
TMPJ-01330
|
CD299 Protein, Human, Recombinant (His & Flag)
DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin do...
|
Human
|
Human Cells
|
|
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso... |
|
TMPY-02352
|
PD-L2 Protein, Mouse, Recombinant (His)
programmed cell death 1 ligand 2,Btdc,F730015O22Rik...
|
Mouse
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPY-02436
|
PD-L2 Protein, Mouse, Recombinant (hFc)
F730015O22Rik,Btdc,PD-L2,programmed cell death 1 li...
|
Mouse
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPY-05282
|
PD-L2 Protein, Mouse, Recombinant (His), Biotinylated
PD-L2,programmed cell death 1 ligand 2,B7-DC,F73001...
|
Mouse
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPH-01235
|
APOBEC3A Protein, Human, Recombinant (His & SUMO)
A3A,APOBEC3A,DNA dC->dU-editing enzyme APOBEC-3A,Ph...
|
Human
|
E. coli
|
|
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a rol... |
|
TMPK-00166
|
PD-L2 Protein, Human, Recombinant (His & Avi)
PDL2,Btdc,Butyrophilin B7-DC,PDCD...
|
Human
|
HEK293
|
|
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. |
|
TMPK-01290
|
PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)
B7DC,PDL2,CD273, PDCD1 ligand 2,Btdc
|
Cynomolgus
|
HEK293
|
|
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. |
|
TMPY-02756
|
MDC Protein, Human, Recombinant (His)
A-152E5.1,MDC,ABCD-1,SCYA22,STCP-1,DC/B-CK...
|
Human
|
E. coli
|
|
Chemokine (C-C motif) ligand 22(ABCD-1 / CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1 / CCL22 chemokine... |
|
TMPH-01903
|
APOBEC3C Protein, Human, Recombinant (GST)
APOBEC3C,Phorbolin I,PBI,APOBEC1-like,A3C,DNA dC->d...
|
Human
|
E. coli
|
|
APOBEC3C Protein, Human, Recombinant (GST) is expressed in E. coli. |
|
TMPY-00120
|
PD-L2 Protein, Human, Recombinant (hFc)
Btdc,B7-DC,programmed cell death 1 ligand ...
|
Human
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPY-06281
|
PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
bA574F11.2,B7DC,B7-DC,PDCD1L2,pro...
|
Human
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPY-05613
|
PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated
bA574F11.2,programmed cell death 1 ligand 2,Btdc,PD...
|
Human
|
HEK293
|
|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B ... |
|
TMPK-01049
|
CLEC7A Protein, Mouse, Recombinant (hFc)
CLECSF12,DC-associated C-type lectin 1,Dectin-1,Bet...
|
Mouse
|
HEK293
|
|
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders. |
|
TMPH-01984
|
CLECL1P Protein, Human, Recombinant (His & Myc)
Putative C-type lectin-like domain family 1,DC-asso...
|
Human
|
Baculovirus
|
|
CLECL1P Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. |
|
TMPY-04298
|
CDCP1 Protein, Human, Recombinant (His)
TRASK,CD318,CUB domain containing protein 1,SIMA135
|
Human
|
HEK293
|
|
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migratio... |
|
TMPY-03835
|
CDCP1 Protein, Rhesus, Recombinant (His)
CUB domain containing protein 1
|
Rhesus
|
HEK293
|
|
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migratio... |
|
TMPY-04722
|
DcR1/TRAILR3 Protein, Human, Recombinant (His)
TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR1-TNFR...
|
Human
|
HEK293
|
|
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC. |
|
TMPJ-00922
|
DCK Protein, Human, Recombinant (His & T7)
DCK,Deoxycytidine Kinase
|
Human
|
E. coli
|
|
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and c... |
|
TMPY-03149
|
CDCP1 Protein, Human, Recombinant (mFc)
TRASK,SIMA135,CD318,CUB domain containing protein 1
|
Human
|
HEK293
|
|
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migratio... |
|
TMPY-02988
|
CDCP1 Protein, Mouse, Recombinant (hFc)
E030027H19Rik,CUB domain containing protein 1,AA409659,90300...
|
Mouse
|
HEK293
|
|
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migratio... |
|
TMPK-00505
|
BDCA-2 Protein, Cynomolgus, Recombinant (His)
CD303,HECL,CLEC4C,DLEC,CLECSF7,CLECSF11,BDCA-2,B
|
Cynomolgus
|
HEK293
|
|
BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three Ags are not detectable on a third blood dendritic cell population, which is CD1c() CD11c(bright) CD123(dim), or on any other cells in blood.BDCA-2 is completely down-regulated on plasmacytoid CD11c(-) CD123(bright) dendritic cells, BDCA-2 is rapidly internalized at 37 degrees C ... |
|
TMPY-03106
|
CCDC47 Protein, Human, Recombinant (His)
GK001,MSTP041,coiled-coil domain containing 47
|
Human
|
HEK293
|
|
CCDC47 gene is expressed at high level. The gene contains 16 distinct gt-ag introns. Transcription produces 9 different mRNAs, 6 alternatively spliced variants and 3 unspliced forms. There are 3 probable alternative promotors, 3 non overlapping alternative last exons and 8 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of a cassette exon, overlapping exons with different boundaries. Functionally, ... |
|
TMPY-03853
|
DCBLD2 Protein, Human, Recombinant (His)
CLCP1,discoidin, CUB and LCCL domain containing 2,ESDN
|
Human
|
HEK293
|
|
DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor med... |
|
TMPY-03400
|
DCBLD1 Protein, Human, Recombinant (His)
dJ94G16.1,discoidin, CUB and LCCL domain containing 1,RP1-94...
|
Human
|
HEK293
|
|
Discoidin, also known as DCBLD1, contains 1 CUB domain, 1 F5/8 type C domain and 1 LCCL domain. It is a 715 amino acid single-pass membrane protein. Discoidin has a discoidin I-like domain which shares a common C-terminal region of about 110 amino acids with the FA58C domain, but whose N-terminal 40 amino acids are much less conserved. Discoidin gene contains 31 distinct gt-ag introns. Transcription produces 18 different mRNAs, 16 alternatively spliced variants and 2 unspliced forms. Discoidin i... |
|
TMPK-01010
|
CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
UNQ2486,TRASK,CD318,SIMA135,CDCP1,PRO5773
|
Mouse
|
HEK293
|
|
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. |
|
TMPK-00965
|
MAdCAM-1 Protein, Human, Recombinant (aa 19-317, hFc)
MADCAM1,MACAM1,MAdCAM-1
|
Human
|
HEK293
|
|
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of our study was to determine whether selected single nucleotide polymorphisms (SNPs) of the MADCAM1 gene are associated with development of serious complications after aHSCT. |
|
TMPK-00504
|
BDCA-2 Protein, Cynomolgus, Recombinant (hFc)
CD303,BDCA-2,DLEC,CLECSF7,BDCA2,CLECSF11,C...
|
Cynomolgus
|
HEK293
|
|
BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three Ags are not detectable on a third blood dendritic cell population, which is CD1c() CD11c(bright) CD123(dim), or on any other cells in blood.BDCA-2 is completely down-regulated on plasmacytoid CD11c(-) CD123(bright) dendritic cells, BDCA-2 is rapidly internalized at 37 degrees C ... |
|
TMPK-00635
|
CDCP1 Protein, Rat, Recombinant (His)
TRASK,SIMA135,UNQ2486,CD318,PRO5773,CDCP1
|
Rat
|
HEK293
|
|
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. |
|
TMPJ-00564
|
PLXDC2 Protein, Mouse, Recombinant (His)
Tumor endothelial marker 7-related protein,Plexin domain-con...
|
Mouse
|
Human Cells
|
|
Mouse Plexin domain-containing protein 2(PLXDC2) is a single-pass type I membrane protein. The protein is expressed in tumor endothelium and in vessels of some normal tissues, such as the muscle and lung. PLXDC2 can interact with CTTN, and may play a role in tumor angiogenesis. |
|
TMPK-01031
|
MAdCAM-1 Protein, Mouse, Recombinant (His)
MACAM1,MADCAM1,MAdCAM-1
|
Mouse
|
HEK293
|
|
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of our study was to determine whether selected single nucleotide polymorphisms (SNPs) of the MADCAM1 gene are associated with development of serious complications after aHSCT. |
|
TMPJ-01298
|
PRADC1 Protein, Human, Recombinant (His)
Protease-associated domain-containing protein of 21 kDa,Prot...
|
Human
|
Human Cells
|
|
PRADC1, also known as C2orf7 or PAP21, is short for Protease-associated domain-containing protein 1. It is a 188 aa. with a 21 aa. signal, and the 171 located Asn can be glycosylated. PRADC1 has two mutagenesis which are N121Q and N171Q. This protein is secreted and highly expressed in skeletal muscle, heart and liver. It is expressed at intermediate level in kidney. |
|
TMPY-00305
|
MDC Protein, Mouse, Recombinant (His)
DCBCK,MDC,ABCD-1,Scya22,chemokine (C-C mot...
|
Mouse
|
E. coli
|
|
Chemokine (C-C motif) ligand 22(ABCD-1 / CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1 / CCL22 chemokine... |
|
TMPJ-00720
|
TXNDC12 Protein, Human, Recombinant (His)
TLP19,ERp19,Thioredoxin Domain-Containing Protein 12,hTLP19,...
|
Human
|
Human Cells
|
|
Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain. |
|
TMPJ-00487
|
SDC1 Protein, Human, Recombinant (hFc)
CD138,SDC,SDC1,Syndecan-1,SYND1
|
Human
|
Human Cells
|
|
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence, and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell prolif... |
沪公网安备 31010602006700号