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Search Results for " neurodegenerative disease "

56

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1880	P7C3	Others	Others
	P7C3 是一种 aminopropyl carbazole 类化合物，具有口服活性，可透过血脑屏障，具有神经保护作用。它可用于神经退行性疾病，如帕金森病的研究。
T8849	PF-9601N	MAO	Metabolism; Neuroscience
	PF-9601N 是一种单胺氧化酶 B (MAO-B) 抑制剂，在多种体内外模型中表现出抗帕金森病 (PD) 的神经保护作用。它可用于研究兴奋性毒性介导的神经退行性疾病。
T22043	BCATc Inhibitor 2	Others	Others
	BCATc Inhibitor 2 是选择性分支链氨基转移酶抑制剂，可用于神经退行性疾病的研究。能够抑制 rBCATc (IC50:0.2 μM)，hBCATc (IC50:0.8 μM)、 rBCATm (IC50:3.0 μM)。其中BCATc 也称为 BCAT1，存在于细胞质基质中的亚型。
T11095L	DREADD agonist 21	5-HT Receptor; Adrenergic Receptor; AChR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	DREADD agonist 21 是一种人毒蕈碱乙酰胆碱 M3 受体激动剂，EC50为 1.7 nM。
T9611	PF-04802367	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	PF-04802367是 GSK-3高选择性抑制剂，对 GSK-3β酶的 IC50为 2.1 nM。它抑制两种 GSK-3 亚型（GSK-3α和GSK-3β）效果差不多，IC50值分别为 10.0 和 9.0 nM。它具有理想的中枢神经系统特性和效力。
T6561	Laquinimod LAQ,ABR-215062,拉喹莫德	Apoptosis; Others; NF-κB	Apoptosis; NF-κB; Others
	Laquinimod (LAQ) 是一种免疫调节剂，可预防中枢神经系统的神经变性和炎症。
T9999	Sirtuin modulator 2 N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide	Others; Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) 具有抗糖尿病、抗炎和抗肿瘤活性。
T8055	TFEB activator 1 (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,(1E,4E)-1,5(2 -甲氧基苯基)-1,4-戊二烯-3-酮,RPN77612	Others; Autophagy	Autophagy; Others
	TFEB activator 1 (Curcumin analog compound C1) 是转录因子 EB 的一种激活剂，有望预防或治疗阿尔茨海默病。
T77708	Casein kinase 1δ-IN-7	Casein Kinase	Metabolism; Stem Cells
	Casein kinase 1δ-IN-7 是一种 Casein kinase 1δ 抑制剂，可用于阿尔茨海默氏病等神经退行性疾病的研究。
T77709	Casein kinase 1δ-IN-8	Casein Kinase	Metabolism; Stem Cells
	Casein kinase 1δ-IN-8 是一种酪蛋白激酶 1δ 的抑制剂，可用于治疗如阿尔茨海默病类型的神经退行性疾病。
T62568	IXA6	IRE1	Cell Cycle/Checkpoint
	IXA6 是一种新型的IRE1/XBP1s激动剂，具有潜在的血管保护活性，可激活 IRE1-XBP1s 信号传导和 XBP1s 转录反应，可用于研究帕金森病和阿尔茨海默病等神经退行性疾病。
T5447	Anle138b	Beta Amyloid; Others	Neuroscience; Others
	Anle138b 是一种毒性低，口服生物利用度高，血脑屏障通透性好的低聚物聚集抑调节剂，可阻断朊病毒蛋白和 α-突触核蛋白病理性聚集的形成。它在体内强烈抑制低聚物积累、神经元变性和疾病进展。它阻断 Aβ 通道并挽救淀粉样变性小鼠模型的疾病表型。
T60295	Casein kinase 1δ-IN-1 WAY-643895	Casein Kinase	Metabolism; Stem Cells
	Casein kinase 1δ-IN-1 (WAY-643895) 是一种酪蛋白激酶 1δ (CK1δ) 的抑制剂，对CK1δ有抑制作用。Casein kinase 1δ-IN-1 可用于如阿尔茨海默病类的神经退行性疾病的研究。
T61809	GSK-3β inhibitor 11	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	GSK-3β inhibitor 11（compound 21）是一种强效的糖原合成酶激酶-3β（GSK-3β）抑制剂，其抑制浓度（IC50）为10.02 μM。该化合物在神经退行性疾病研究领域展示了潜在的应用价值[1]。
T16881L	SIB 1553A	AChR	Neuroscience
	SIB 1553A 是一种可口服且具有选择性的烟碱乙酰胆碱受体 (nAChRs) 激动剂，是烟碱乙酰胆碱受体的亚型选择性配体。SIB-1553A 是一种认知增强剂，可用于研究如阿尔茨海默病等与神经退行性相关的疾病。
T61439	DSS30	Beta Amyloid; BACE; CDK	Cell Cycle/Checkpoint; Neuroscience
	DSS30 是一种 P25/CDK5抑制剂。DSS30通过抑制淀粉样前体蛋白裂解酶1 (BACEl) 磷酸化，减少 β-淀粉样蛋白 (Aβ) 的分泌发挥作用。DSS30 可用于预防和治疗阿尔茨海默病等神经退行性疾病。
T1993	J-147 J147	Epigenetic Reader Domain; Dopamine Receptor; Monoamine Oxidase	Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
	J-147 是一种高效的、具有口服活性的、可透过血脑屏障神经保护剂，可增强认知能力。它抑制单胺氧化酶 B 和多巴胺转运体，EC50分别为 1.88 μM 和 0.649 μM。它有研究阿尔茨海默氏症的潜力。
T63321	20S Proteasome activator 1	Proteasome	Proteases/Proteasome; Ubiquitination
	20S Proteasome activator 1 是一种 20S 蛋白酶激活剂，对胰蛋白酶样位点、胰凝乳蛋白酶样位点和半胱天冬酶位点的 IC50 分别为 0.3 μM、0.7 μM 和 1.8 μM。20S Proteasome activator 1 通过在细胞系统中翻译来防止致病性 α-synuclein A53T 突变体积累从而减少疾病发生的概率。20S Proteasome activator 1 可用于研究神经退行性疾病。
T40766	1,2,3,4-Tetrahydro-β-carboline-1-carboxylic acid
	1,2,3,4-Tetrahydro-β-carboline-1-carboxylic acid is a neuroactive compound utilized in neurodegenerative disease research.
T61662	O-GlcNAcase-IN-4
	O-GlcNAcase-IN-4 is an inhibitor of O-GlcNAcase. It holds potential for researching neurodegenerative diseases and disorders, including Alzheimer's disease [1].
T68950	Hepta-histidine
	Hepta-histidine is a novel inhibitor of Tau aggregation against Tau-related neurodegenerative diseases including Alzheimer's disease (AD).
TP1320	Angiogenin (108-122) TFA (112173-49-6 free base) Angiogenin (108-122) TFA
	Angiogenin (108-122) TFA is an angiogenin peptide.Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an autoimmu
TP1362	Angiogenin (108-122) Angiogenin 108-122
	Angiogenin (108-122) is an angiogenin peptide. Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an autoimmune
T30266	AZD8926 AZD 8926,AZD-8926
	AZD8926 is a potent and selective inhibitor of GSK3β(glycogen synthase kinase-3β). AZD8926 is potential for treating Alzheimer’s disease (AD), schizophrenia, and chronic as well as acute neurodegenerative diseases.
T77610	WAY-339495	Others	Others
	WAY-339495 可能具有抗肿瘤抗炎和镇痛活性，可用来研究肥胖、心血管疾病、糖尿病、神经退行性疾病、阿尔茨海默病和中风。
T75751	β-Amyloid (1-40) (TFA)
	β-Amyloid (1-40) TFA 是阿尔茨海默症患者脑斑块中发现的一种主要蛋白片段。
T79857	Risevistinel NYX-783	iGluR	Membrane transporter/Ion channel; Neuroscience
	Risevistinel (NYX-783)，一种N-甲基-D-天冬氨酸 (NMDA) 受体正变构调节剂，旨在缓解与神经退行性疾病相关的认知功能障碍，包括轻度认知障碍、阿尔茨海默病初期、帕金森病及路易体病等病症。
T79855	Nevadistinel NYX-458,NYX-3054	iGluR	Membrane transporter/Ion channel; Neuroscience
	Nevadistinel (NYX-458; NYX-3054) 是一种NMDA受体的正变构调节剂，主要应用于抑制与神经退行性疾病相关的认知障碍，疾病包括轻度认知障碍、轻度阿尔茨海默病、帕金森病和路易体病。
TP2069	BDNF (human)
	Member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. Enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and A
T61128	c-ABL-IN-2
	C-ABL-IN-2 is a highly effective inhibitor of the c-Abl protein, which plays a significant role in the development of several diseases, including cancer. This compound exhibits promise for investigating neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD), as well as cancer. (Source: WO2020260871A1, compound 25) [1].
T62534	POP-IN-2
	POP-IN-2 (Compound 7k) 是一种有效的、共价结合的 prolyl oligopeptidase (POP) 抑制剂 (Ki: 6 nM)。POP-IN-2 能够用于神经退行性疾病和癌症的研究。
T80118	α-Synuclein (61-95) (human)
	α-Synuclein(61-95) (human) 是 α-Synuclein 的疏水核心区段，具有诱导神经元死亡的能力。该肽段在神经退行性疾病的研究中有应用，涉及阿尔茨海默病 (AD) 与帕金森病 (PD)。
T74097	THX-B
	THX-B为一高效非多肽类p75NTR（神经营养蛋白受体p75）拮抗剂，适用于糖尿病、肾病、神经退行性及炎症性疾病研究。
T61546	c-ABL-IN-3
	c-ABL-IN-3, a highly effective c-Abl inhibitor, exhibits promising potential for studying neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD), as well as cancer [1]. The activation of c-Abl has been strongly implicated in a range of diseases, notably cancer [1]. It offers valuable opportunities for research in these fields [1].
T60591	A2AAR antagonist 1
	A2AAR antagonist 1 (compound 21a) 是A2AAR(腺苷A2A 受体) 的拮抗剂，具有高配体效率，Ki 值为 20 nM。A2AAR antagonist 1 可用于神经退行性疾病的相关研究。
TP1673	β-Amyloid (11-22) β-Amyloid 11-22
	β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). AD is the most common neurodegenerat
T81251	rTRD01
	rTRD01为TDP-43配体，与TDP-43的RRM1和RRM2结构域结合(Kd=89 uM，TDP-43102-269)。该化合物能够削弱TDP-43与与疾病相关的c9orf72基因的六核苷酸RNA的交互作用，可作为神经退行性疾病研究的工具。
T81820	meso-Benzothiazole-BODIPY 505/515
	meso-Benzothiazole-BODIPY 505/515 是一种BODIPY荧光探针，具备优异的粘度反应性及AIE特性，能够监测细胞内粘度变化与自噬过程。该探针适用于阿尔茨海默病、溶酶体贮积病以及其他神经退行性疾病的研究。
T60824	Dyrk1A-IN-3
	Dyrk1A-IN-3 (Compound 8b) 是双特异性酪氨酸调节激酶 1A (DYRK1A) 的高选择性抑制剂。Dyrk1A-IN-3与 DYRK1A 结合具有高结合亲和力，IC50值为76 nM。Dyrk1A-IN-3可用于研究神经退行性疾病，例如，阿尔茨海默病、亨廷顿病和帕金森病等。
T79010	Lp-PLA2-IN-12	Phospholipase	Metabolism
	Lp-PLA2-IN-12（compound 19）为一种Lp-PLA2抑制剂，主要应用于神经退行性疾病（如AD、青光眼、AMD）及心血管疾病（诸如动脉粥样硬化）的研究。
T79333	LZWL02003	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	LZWL02003为抗神经炎症化合物，对MPP+引起的神经元损害展示保护效果，有效降低ROS水平。此外，LZWL02003能改善鱼藤酮诱导的帕金森病(PD)大鼠模型在认知、记忆、学习及运动能力方面的缺陷。该化合物在神经退行性疾病的研究中具有应用潜力。
T79154	Casein kinase 1δ-IN-5	Casein Kinase	Metabolism; Stem Cells
	Casein kinase1δ-IN-5为一种高效的蛋白激酶CK-1δ选择性抑制剂，IC50值为47 nM。该化合物在体外展现出神经保护和抗炎效果，具备应用于神经退行性疾病研究的潜力。
T35804	C16 Lactosylceramide (d18:1/16:0)
	C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle. C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.
T35809	C20 Sphingomyelin (d18:1/20:0)
	C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. The plasma concentration of C20 sphingomyelin is decreased in m...
T62612	CD33 splicing modulator 1
	CD33 splicing modulator 1 (Compound 1) 是一种 CD33 splicing modulator。CD33/Siglec 3 是一种已知可调节小胶质细胞活性的髓系细胞表面受体。CD33 splicing modulator 1 加强了细胞 mRNA 池中外显子 2 的跳跃。CD33 splicing modulator 1 具有潜力进行包括阿尔茨海默病在内的神经退行性疾病的研究。
T78833	AJH-836	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	AJH-836为Munc13-1及PKCε/α激活剂（Kd：4.5 nM PKCα），促进Munc13-1由细胞质转位至质膜，并可应用于神经退行性疾病研究。
T35594	Cuspin-1
	The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA). Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 μM. Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Ra...
T80106	Z-Pro-Pro-aldehyde-dimethyl acetal	Prolyl Endopeptidase (PREP)	Metabolism; Proteases/Proteasome
	Z-Pro-Pro-aldehyde-dimethyl acetal 是一种高效的脯氨酸内肽酶(PRE P)抑制剂，其IC50值为12 nM。该化合物在衰老过程和神经退行性疾病，诸如阿尔茨海默病中认知功能障碍的研究中具有重要作用。
T82763	CD33 splicing modulator 1 hydrochloride
	"CD33splicing modulator 1 (Compound 1) hydrochloride 是一种调节CD33/Siglec 3活性的化合物。CD33/Siglec 3 为髓系细胞表面受体，涉及小胶质细胞功能。该化合物通过提升细胞mRNA池中外显子2的剪接变异，展现在神经退行性疾病研究中的应用潜力，包括阿尔茨海默病。"
T73289	mHTT-IN-1
	mHTT-IN-1 (Example 1) 为针对突变亨廷顿蛋白 (mHTT) 的高效抑制剂，该蛋白具毒性，主导遗传性常染色体显性神经退行性疾病—亨廷顿氏病 (HD) 的发生。mHTT-IN-1 能有效降低 mHTT 水平，其 EC50 值为 0.46 nM。

化合物

Cat.No: T1880

Target: Others

Cat.No: T8849

Target: MAO

BCATc Inhibitor 2

Cat.No: T22043

Target: Others

DREADD agonist 21

Cat.No: T11095L

Target: 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor

Cat.No: T9611

Target: GSK-3

Cat.No: T6561

Synonym: LAQ,ABR-215062,拉喹莫德

Target: Apoptosis, Others, NF-κB

Sirtuin modulator 2

Cat.No: T9999

Synonym: N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide

Target: Others, Sirtuin

TFEB activator 1

Cat.No: T8055

Synonym: (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,(1E,4E)-1,5(2 -甲氧基苯基)-1,4-戊二烯-3-酮,RPN77612

Target: Others, Autophagy

Casein kinase 1δ-IN-7

Cat.No: T77708

Target: Casein Kinase

Casein kinase 1δ-IN-8

Cat.No: T77709

Target: Casein Kinase

Cat.No: T62568

Target: IRE1

Cat.No: T5447

Target: Beta Amyloid, Others

Casein kinase 1δ-IN-1

Cat.No: T60295

Synonym: WAY-643895

Target: Casein Kinase

GSK-3β inhibitor 11

Cat.No: T61809

Target: GSK-3

Cat.No: T16881L

Target: AChR

Cat.No: T61439

Target: Beta Amyloid, BACE, CDK

Cat.No: T1993

Synonym: J147

Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase

20S Proteasome activator 1

Cat.No: T63321

Target: Proteasome

1,2,3,4-Tetrahydro-β-carboline-1-carboxylic acid

Cat.No: T40766

O-GlcNAcase-IN-4

Cat.No: T61662

Hepta-histidine

Cat.No: T68950

Angiogenin (108-122) TFA (112173-49-6 free base)

Cat.No: TP1320

Synonym: Angiogenin (108-122) TFA

Angiogenin (108-122)

Cat.No: TP1362

Synonym: Angiogenin 108-122

Cat.No: T30266

Synonym: AZD 8926,AZD-8926

Cat.No: T77610

Target: Others

β-Amyloid (1-40) (TFA)

Cat.No: T75751

Cat.No: T79857

Synonym: NYX-783

Target: iGluR

Cat.No: T79855

Synonym: NYX-458,NYX-3054

Target: iGluR

Cat.No: TP2069

Cat.No: T61128

Cat.No: T62534

α-Synuclein (61-95) (human)

Cat.No: T80118

Cat.No: T74097

Cat.No: T61546

A2AAR antagonist 1

Cat.No: T60591

β-Amyloid (11-22)

Cat.No: TP1673

Synonym: β-Amyloid 11-22

Cat.No: T81251

meso-Benzothiazole-BODIPY 505/515

Cat.No: T81820

Cat.No: T60824

Cat.No: T79010

Target: Phospholipase

Cat.No: T79333

Target: Reactive Oxygen Species

Casein kinase 1δ-IN-5

Cat.No: T79154

Target: Casein Kinase

C16 Lactosylceramide (d18:1/16:0)

Cat.No: T35804

C20 Sphingomyelin (d18:1/20:0)

Cat.No: T35809

CD33 splicing modulator 1

Cat.No: T62612

Cat.No: T78833

Target: PKC

Cat.No: T35594

Z-Pro-Pro-aldehyde-dimethyl acetal

Cat.No: T80106

Target: Prolyl Endopeptidase (PREP)

CD33 splicing modulator 1 hydrochloride

Cat.No: T82763

Cat.No: T73289

Cat. No.	Product Name	Target	Signaling Pathways
T21883	Gedunin	HSP	Cytoskeletal Signaling; Metabolism
	Gedunin 是从印楝种子中提取的一种重要柠檬苦素，具有抗癌、抗病毒、抗炎和杀虫活性。它可阻断 SARS-CoV-2 病毒进入人宿主细胞，用于 COVID-19 研究。它是Hsp90抑制剂，诱导 Hsp90 依赖的蛋白降解，抑制卵巢癌细胞增殖。
T0086	Galanthamine hydrobromide Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏	AChR; AChE	Neuroscience
	Galanthamine hydrobromide (Galantamine hydrobromide) 是一种长效的中枢活性 AChE 抑制剂，IC50为 410 nM。它是神经元烟碱型 ACh 受体的变构增强剂，IC50值为 0.35 µM，可用于阿尔茨海默症的研究。
T3026	(-)-Huperzine A HupA,石杉碱,Huperzine A,石杉碱甲	Apoptosis; AChR; AChE; iGluR	Apoptosis; Membrane transporter/Ion channel; Neuroscience
	(-)-Huperzine A (HupA) 是从中国梅花苔中分离得到的一种生物碱，具有神经保护活性。它是高特异性可逆的，具有血脑屏障渗透性的一种乙酰胆碱酯酶抑制剂，其IC50值为 82 nM。它也是 N-甲基-D-天冬氨酸受体的非竞争性拮抗剂，可研究神经退行性疾病，如阿尔茨海默病。
T4956	Tetrahydroxystilbene-2-O-β-D-glucoside tetrahydroxyl diphenylethylene-2-o-gluco,何首乌苷,EH-201	Others	Others
	Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) 是一种低分子量的促红细胞生成素诱导剂。
T4S0797	Berberine 小檗碱,Berberin,Umbellatine,黄连素	Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Berberine (Umbellatine) 是从中草药黄连中分离出来的一种生物碱抗生素。它诱导活性氧生成并抑制 DNA 拓扑异构酶，具有抗肿瘤特性。
T2S2215	Crebanine	Apoptosis; Others; Akt	Apoptosis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling
	Crebanine 是来自于韦诺萨千金藤的一种生物碱，通过抑制 MAPKs 和 Akt 信号通路表现出抗炎活性，还具有抗心律失常的作用。它可诱导人类癌细胞的 G1阻滞和凋亡。
T38606	Sinapine hydroxide
	Sinapine hydroxide, an alkaloid derived from the seeds of cruciferous plants, demonstrates a variety of beneficial properties including anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic, and radio-protective effects. Additionally, it acts as an inhibitor of acetylcholinesterase (AChE), making it valuable for researching neurodegenerative conditions such as Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease[4].
T75527	Chrexanthomycin C
	Chrexanthomycin C 是一种具有显著生物活性的海洋天然产物，具有口服活性。Chrexanthomycin C 对 DNA (G4C2)4 G4 具有结合亲和力，Kd 值为 2.8 mM。Chrexanthomycin C 可用于肌萎缩侧索硬化症 (ALS) 等神经退行性疾病的研究。

天然产物

Cat.No: T21883

Target: HSP

Galanthamine hydrobromide

Cat.No: T0086

Synonym: Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏

Target: AChR, AChE

(-)-Huperzine A

Cat.No: T3026

Synonym: HupA,石杉碱,Huperzine A,石杉碱甲

Target: Apoptosis, AChR, AChE, iGluR

Tetrahydroxystilbene-2-O-β-D-glucoside

Cat.No: T4956

Synonym: tetrahydroxyl diphenylethylene-2-o-gluco,何首乌苷,EH-201

Target: Others

Cat.No: T4S0797

Synonym: 小檗碱,Berberin,Umbellatine,黄连素

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Cat.No: T2S2215

Target: Apoptosis, Others, Akt

Sinapine hydroxide

Cat.No: T38606

Chrexanthomycin C

Cat.No: T75527

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