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650

抑制剂 & 化合物

74

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37422L	Ras Inhibitory Peptide acetate Ras Inhibitory Peptide acetate(159088-48-9 Free base)	Ras	GPCR/G Protein; MAPK
	Ras Inhibitory Peptide acetate 是一种参与 Ras 依赖性信号通路的肽，Ras 在致癌受体引发的人类癌症中起重要作用。
T16432	Pan-RAS-IN-1	MAPK; Ras	GPCR/G Protein; MAPK
	Pan-RAS-IN-1是一种广谱的 Ras 抑制剂。Pan-RAS-IN-1破坏 Ras 蛋白及其作用子的相互作用。
T5469	K-Ras-IN-1	Raf; Ras	GPCR/G Protein; MAPK
	K-Ras-IN-1 是K-Ras 抑制剂。K-Ras-IN-1 能与 K-Ras (WT)、K-Ras (G12D)、K-Ras (G12V) 和 H-Ras 结合。它对胰腺癌、结肠癌和肺癌的具潜在的研究价值。
T11738	K-Ras G12C-IN-4	Ras	GPCR/G Protein; MAPK
	K-Ras G12C-IN-4 是一种 KRAS G12C 共价抑制剂。
T12692	RAS GTPase inhibitor 1	Others	Others
	RAS GTPase inhibitor 1 is a inhibitor of RAS GTPase, with anti-tumor activity.
T6556	K-Ras(G12C) inhibitor 9	Raf	MAPK
	K-Ras(G12C) inhibitor 9 是致癌 K-Ras(G12C) 的变构抑制剂。
T3725	K-Ras(G12C) Inhibitor 6	Raf	MAPK
	KRas(G12C) inhibitor 6 是一种变构的，选择性的 K-Ras(G12C)抑制剂。
T6555	K-Ras(G12C) inhibitor 12	Apoptosis; Raf; Ras	Apoptosis; GPCR/G Protein; MAPK
	K-Ras(G12C) inhibitor 12是一种K-Ras(G12C)抑制剂，作用于H1792细胞，EC50为0.32 μM。
T8659	K-Ras-PDEδ-IN-1	PDE	Metabolism
	K-Ras-PDEδ-IN-1 是新型的 K-Ras-PDEδ 抑制剂，它能够以低纳摩尔Kd8 nM 与 PDEδ 的法尼基结合袋竞争性结合。
T36642	RAS/RAS-RAF-IN-1
	RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1]. RAS/RAS-RAF-IN-1 (compound 89; for 4 hours) has an EC50 of 0.5 μμ-5.0 μμ for BRAF-GTP-KRAS-G12C disruption and has an IC50 of 1.0 μμ-10 μμ for pERK inhibition in H358 cells[1]. [1]. Meizhong Jin, et al. Compounds that participate in cooperative binding and uses thereof. WO2020132597A1.
T74698	RMC-6236 RAS-IN-2
	RMC-6236（RAS-IN-2 ) 是一种有效的RAS(ON)MULTI 抑制剂，可用于癌症的研究。
T37422	Ras Inhibitory Peptide
	Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction ...
T36641	RAS inhibitor Abd-7
	RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders RAS-effector interactions and suppresses endogenous RAS-dependent signaling. Additionally, RAS inhibitor Abd-7 disrupts the PPI of different mutant KRAS proteins with PI3K, CRAF, RALGDS, as well as NRAS Q61H and HRAS G12V[1].
T77800	Ras inhibitor 134

T13844	PROTAC K-Ras Degrader-1	Ras	GPCR/G Protein; MAPK
	PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
T11735	K-Ras G12C-IN-1	Phosphatase	Metabolism
	K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.
T11737	K-Ras G12C-IN-3	Others	Others
	Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.
T11736	K-Ras G12C-IN-2	Others	Others
	K-Ras G12C-IN-2 is a covalent kras g12c inhibitor.
T18056	K-Ras ligand-Linker Conjugate 3	Others	Others
	K-Ras ligand-Linker Conjugate 3 (Compound 001371) is a chemical compound that consists of a ligand for K-Ras recruiting moiety and a PROTAC linker, responsible for recruiting E3 ligases (e.g., VHL, CRBN, MDM2, and IAP). This compound is essential in the synthesis of PROTAC K-Ras Degrader-1, a potent PROTAC K-Ras degrader that demonstrates a degradation efficacy of ≥70% in SW1573 cells[1].
T18055	K-Ras ligand-Linker Conjugate 2	Others	Others
	K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesis of PROTAC K-Ras Degrader-1, which is a highly effective PROTAC K-Ras degrader with a degradation efficacy of ≥70% in SW1573 cells[1].
T18057	K-Ras ligand-Linker Conjugate 4	Others	Others
	K-Ras ligand-Linker Conjugate 4 is a chemical compound that combines a ligand for K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The compound has the potential to be used in the synthesis of PROTAC K-Ras Degrader-1, a powerful degrader of K-Ras that has been shown to exhibit a degradation efficacy of ≥70% in SW1573 cells[1].
T18059	K-Ras ligand-Linker Conjugate 6	Others	Others
	K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for K-Ras recruiting moiety and a PROTAC linker. This compound can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker Conjugate 6 is particularly useful in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
T18058	K-Ras ligand-Linker Conjugate 5	Others	Others
	K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The K-Ras ligand-Linker Conjugate 5 plays a crucial role in the synthesis of PROTAC K-Ras Degrader-1, a highly potent K-Ras degrader. In SW1573 cells, this degrader exhibits an impressive degradation efficacy of ≥70% [1].
T18054	K-Ras ligand-Linker Conjugate 1	Others	Others
	K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
T72774	Ras modulator-1
	Rasmodulator-1 是Ras 调节剂。
T1931	6H05 K-Ras inhibitor	Raf; Ras	GPCR/G Protein; MAPK
	6H05 (K-Ras inhibitor) 是致癌突变体 K-Ras(G12C) 的选择性变构抑制剂。
T1892	Kobe2602	Raf; Ras	GPCR/G Protein; MAPK
	Kobe2602 是 Ras-Raf 相互作用抑制剂，具有抗癌化疗活性。它抑制 H-Ras·GTP 与 c-Raf-1 RBD 结合的Ki 值为 149 μM。
T39099	G12 Ras 5-17
	G12 (Ras 5-17) is a wild-type Ras peptide composed of amino acids 5-17, specifically KLVVVGAGGVGKS. It can serve as a control in studies focused on mutant Ras peptides, like V12.
T6462	Deltarasin	PDE; Ras	GPCR/G Protein; MAPK; Metabolism
	Deltarasin 是一种 KRAS-PDEδ 相互作用的小分子抑制剂，与纯化的 PDEδ 结合，Kd 值为 38 nM。
T4370	Resminostat hydrochloride 4SC-201 hydrochloride,RAS2410 hydrochloride	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Resminostat hydrochloride (RAS2410 hydrochloride) 是HDAC1，HHDAC3和HDAC6抑制剂，IC50值分别为 42.5、50.1和71.8 nM，对 HDAC8 的活性较低，IC50值为 877 nM。
T9407	Rasarfin	Others; Ras	GPCR/G Protein; MAPK; Others
	Rasarfin 是Ras 和ARF6双抑制剂。
T2678	LB42708	Transferase	Metabolism
	LB42708 是一种口服有活力的特异性法尼基转移酶抑制剂。它对H-Ras、N-Ras 和K-Ras4B 的法尼基化均有抑制作用，其IC50分别为 0.8 nM、1.2 nM 和 2.0 nM。
T1876	Kobe0065	Apoptosis; Raf; Ras	Apoptosis; GPCR/G Protein; MAPK
	Kobe0065 是一种新型 Ras-Raf 相互作用抑制剂，可完全抑制 H-Ras·GTP 与 c-Raf-1 RBD 的结合，Ki 值为 46±13 μM。
T60029	SOS1-IN-11	Raf	MAPK
	SOS1-IN-11 是一种有效的 SOS1 抑制剂 (IC50 = 30 nM)。
T20759	XRP44X XRP-44-X,XRP 44X,XRP-44X,XRP 44 X	Ras	GPCR/G Protein; MAPK
	XRP44X (XRP 44X) 是Ras 诱导的转录激活的抑制剂，IC50为 10 nM，通过 FGF-2 抑制 Ras-Erk-1/2 通路激活。它抑制Elk3。它还对微管有影响。
T9986	(E/Z)-ZINC09659342	Rho	Cell Cycle/Checkpoint
	(E/Z)-ZINC09659342 是 Lbc-RhoA 相互作用的抑制剂。
T5597	ZT-12-037-01	Serine Protease; Ras	GPCR/G Protein; MAPK; Proteases/Proteasome
	ZT-12-037-01 是一种 ATP 竞争性 STK19 抑制剂，对 STK19 (WT) 和 STK19 (D89N) 的 IC50 值分别为 23.96 和 27.94 nM
T10375	ARS-1323	Ras	GPCR/G Protein; MAPK
	ARS-1323 是 ARS-1620 的消旋体。ARS-1323 是突变型K-Ras G12C 的新型抑制剂。
T2267	BQU57	GTPase; Ras	GPCR/G Protein; MAPK
	BQU57 能够选择性抑制 Ral，且对 Ral 的选择性高于 Ras、Rho，能够作用于 H2122(IC50:2.0 μM)和 H358(IC50:1.3 μM)。
T10376	ARS-1630	Ras	GPCR/G Protein; MAPK
	ARS-1630 是一种突变型 K-ras G12C 抑制剂。它是 ARS-1620 的活性较低的对映异构体。
T6634	RBC8	GTPase; Ras	GPCR/G Protein; MAPK
	RBC8是一种特异性 GTP 酶 RalA/RalB 抑制剂，通过抑制 Ral 与其效应物 RALBP1 的结合，对 GTP 酶 RhoA 和 Ras 没有抑制作用。
T7609	ARS-1620	Ras	GPCR/G Protein; MAPK
	ARS-1620 是 K-RASG12C 的共价抑制剂，具有理想的药代动力学。
T3553	Y16	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	Y16 是一种 G 蛋白偶联的 Rho GEFs 抑制剂，与 Rhosin/G04 协同作用，抑制 LARG-RhoA 相互作用、RhoA 激活和 RhoA 介导的信号传导功能。它是 LARG 的特异性抑制剂，Kd 值为 76 nM。
T5418	BAY-293	Raf; Ras	GPCR/G Protein; MAPK
	BAY-293 是化学探针，是一种有效的细胞活性 SOS1 抑制剂，可破坏 KRAS-SOS1 相互作用，IC50为 21 nM。
T39738	ASP2453	Ras	GPCR/G Protein; MAPK
	ASP2453是选择性的KRAS G12C 共价抑制剂，抑制Son of Sevenless 介导的KRAS G12C 和Raf 之间的相互作用，IC50为40 nM。
T10533	BI-2852	Ras	GPCR/G Protein; MAPK
	BI-2852 是具有纳摩尔亲和力的开关 I/II 口袋（SI/II-口袋）的 KRAS 抑制剂，可抑制 KRAS 突变细胞的下游信号传导和抗增殖作用。
T38050	CP-609754	Transferase	Metabolism
	CP-609754 是高效的、可逆的法尼基转移酶抑制剂，对重组人 H-Ras 和重组 K-Ras 法尼基化的 IC50分别为 0.57 ng/mL 和 46 ng/mL。CP-609754有潜在的抗癌作用。
T8006	Oncrasin-1 1-(4-氯苄基)-1H-吲哚-3-甲醛	Apoptosis; Raf; Ras	Apoptosis; GPCR/G Protein; MAPK
	Oncrasin 1 是一种有效的抗癌抑制剂，可在低或亚微摩尔浓度下杀死具有 K-Ras 突变的各种人类肺癌细胞。
T16021	MBQ-167	CDK; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	MBQ-167 是一种 Rac/Cdc42 的双重抑制剂，在 MDA-MB-231 细胞中，Rac 1/2/3 和 Cdc42 的 IC50 分别为 103 nM 和 78 nM。
T14004	1A-116	Rho	Cell Cycle/Checkpoint
	1A-116 是 Rac1的抑制剂，对几种类型的癌症具有抗肿瘤和抗转移作用，如乳腺癌。

化合物

Ras Inhibitory Peptide acetate

Cat.No: T37422L

Synonym: Ras Inhibitory Peptide acetate(159088-48-9 Free base)

Target: Ras

Cat.No: T16432

Target: MAPK, Ras

Cat.No: T5469

Target: Raf, Ras

K-Ras G12C-IN-4

Cat.No: T11738

Target: Ras

RAS GTPase inhibitor 1

Cat.No: T12692

Target: Others

K-Ras(G12C) inhibitor 9

Cat.No: T6556

Target: Raf

K-Ras(G12C) Inhibitor 6

Cat.No: T3725

Target: Raf

K-Ras(G12C) inhibitor 12

Cat.No: T6555

Target: Apoptosis, Raf, Ras

K-Ras-PDEδ-IN-1

Cat.No: T8659

Target: PDE

RAS/RAS-RAF-IN-1

Cat.No: T36642

Cat.No: T74698

Synonym: RAS-IN-2

Ras Inhibitory Peptide

Cat.No: T37422

RAS inhibitor Abd-7

Cat.No: T36641

Ras inhibitor 134

Cat.No: T77800

PROTAC K-Ras Degrader-1

Cat.No: T13844

Target: Ras

K-Ras G12C-IN-1

Cat.No: T11735

Target: Phosphatase

K-Ras G12C-IN-3

Cat.No: T11737

Target: Others

K-Ras G12C-IN-2

Cat.No: T11736

Target: Others

K-Ras ligand-Linker Conjugate 3

Cat.No: T18056

Target: Others

K-Ras ligand-Linker Conjugate 2

Cat.No: T18055

Target: Others

K-Ras ligand-Linker Conjugate 4

Cat.No: T18057

Target: Others

K-Ras ligand-Linker Conjugate 6

Cat.No: T18059

Target: Others

K-Ras ligand-Linker Conjugate 5

Cat.No: T18058

Target: Others

K-Ras ligand-Linker Conjugate 1

Cat.No: T18054

Target: Others

Ras modulator-1

Cat.No: T72774

Cat.No: T1931

Synonym: K-Ras inhibitor

Target: Raf, Ras

Cat.No: T1892

Target: Raf, Ras

Cat.No: T39099

Synonym: Ras 5-17

Cat.No: T6462

Target: PDE, Ras

Resminostat hydrochloride

Cat.No: T4370

Synonym: 4SC-201 hydrochloride,RAS2410 hydrochloride

Target: HDAC

Cat.No: T9407

Target: Others, Ras

Cat.No: T2678

Target: Transferase

Cat.No: T1876

Target: Apoptosis, Raf, Ras

Cat.No: T60029

Target: Raf

Cat.No: T20759

Synonym: XRP-44-X,XRP 44X,XRP-44X,XRP 44 X

Target: Ras

(E/Z)-ZINC09659342

Cat.No: T9986

Target: Rho

Cat.No: T5597

Target: Serine Protease, Ras

Cat.No: T10375

Target: Ras

Cat.No: T2267

Target: GTPase, Ras

Cat.No: T10376

Target: Ras

Cat.No: T6634

Target: GTPase, Ras

Cat.No: T7609

Target: Ras

Cat.No: T3553

Target: Rho, Ras

Cat.No: T5418

Target: Raf, Ras

Cat.No: T39738

Target: Ras

Cat.No: T10533

Target: Ras

Cat.No: T38050

Target: Transferase

Cat.No: T8006

Synonym: 1-(4-氯苄基)-1H-吲哚-3-甲醛

Target: Apoptosis, Raf, Ras

Cat.No: T16021

Target: CDK, Ras

Cat.No: T14004

Target: Rho

Cat. No.	Product Name	Target	Signaling Pathways
T5S1261	Methylophiopogonanone B	Ras	GPCR/G Protein; MAPK
	Methylophiopogonanone B 是一种高异二氢黄酮，提取自麦冬的根，抗氧化能力强，它通过 Rho 信号传导途径及增加 GTP-Rho 发挥效果。它能够重组肌动蛋白细胞骨架，使细胞形态（如树突收缩、应力纤维形成）发生变化。
T5S0777	Phellodendrine chloride	Others	Others
	Phellodendrine chloride 是一种Phellodendron amurense 中的生物碱。它通过巨胞饮抑制营养物质的吸收，进而抑制 KRAS 突变的胰腺癌细胞的增殖。
T5368	Eicosapentaenoic Acid	Histone Demethylase; Others; Endogenous Metabolite	Chromatin/Epigenetic; Metabolism; Others
	Eicosapentaenoic Acid 是一种 ω-3 脂肪酸。
TQ0165	Arglabin 阿格拉宾,(+)-Arglabin	NOD-like Receptor (NLR); Transferase; NOD; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Arglabin ((+)-Arglabin) 是从青蒿中分离出的一种天然产物，是一种 NLRP3 炎性体抑制剂，具有抗动脉粥样硬化和抗癌作用。
TN1413	Atranorin 荔枝素，巴美灵,荔枝素	Endogenous Metabolite; NO Synthase; Ras	GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism
	Atranorin 是地衣的次生代谢产物，具有显着的抗伤害、抗炎和氧化还原活性，对 H(2)O(2) 诱导的氧化应激下的细胞具有细胞保护作用。
T7131	Antineoplaston A10 3-苯基乙酰氨基-2,6-哌啶二酮,NSC-648539	Apoptosis; Endogenous Metabolite; Ras	Apoptosis; GPCR/G Protein; MAPK; Metabolism
	Antineoplaston A10 (NSC-648539) 是存在于人体内的一种天然产物，可研究胶质瘤、淋巴瘤、星形细胞瘤和乳腺癌，是一种 Ras 抑制剂。
T8244	Raspberry ketone glucoside 覆盆子酮葡糖苷,树莓苷，覆盆子酮葡萄糖甙	Others	Others
	Raspberry ketone glucoside 是一种山莓果实中的天然产物。它能够抑制黑色素的合成。
T41372	(22S,23S)-Homobrassinolide 油菜素内酯,SSHB	Others	Others
	(22S,23S)-Homobrassinolide (SSHB) 在各种植物生物测定试验中均能诱导植物生长。
T15753	Licraside Licuraside	Tyrosinase	Proteases/Proteasome
	Licraside 是一种酪氨酸酶抑制剂，对单酚酶的 IC50 为 0.072 mM，可用于抗褐变和脱色剂的研究。
T4S1114	Dryocrassin ABBA 东北贯众素,Dryocrassin	Influenza Virus; Antibacterial	Microbiology/Virology
	Dryocrassin ABBA (Dryocrassin) 是一种从苦参中提取的黄酮类天然产物，具有抗病毒和抗菌活性。它抑制树突状细胞的免疫刺激功能，延长同种异体皮肤移植成活率。
T3345	Hederasaponin B 常春藤皂苷B,Eleutheroside M,刺五加叶中,Hederacoside B	Others; Virus Protease	Microbiology/Virology; Others
	Hederasaponin B (Hederacoside B) 是从Hedera helix 中分离的，有广谱抗病毒活性。
TN7077	Sinocrassoside C1	Others	Others
	Sinocrassoside C1 是中国景天（景天科）全植物的甲醇提取物。
T7132	(Rac)-Brassinazole BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑	P450	Metabolism
	(Rac)-Brassinazole 是三唑型化合物，是油菜素甾醇 (BR) 生物合成抑制剂。它能够增强 CYP90B 在 BR 生物合成中的抑制作用。
T2S0633	Raspberry ketone Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone,覆盆子酮	PPAR	DNA Damage/DNA Repair; Metabolism
	Raspberry ketone (p-Hydroxybenzyl acetone) 是覆盆子中主要的芳香族天然产物，主要用作化妆品的香料和食品增味剂，也可作 PPAR-α激动剂。
T3151	Brassinolide Brassin lactone,24-Epibrassinolide,芸苔素内酯	Apoptosis; Others	Apoptosis; Others
	Brassinolide (Brassin lactone) 是一种植物生长调节剂，可调节植物细胞伸长。
T4373	Brassinin BSN,芸苔宁	Antifungal	Microbiology/Virology
	Brassinin (BSN) 是一种从 B. campestris 中分离出来的植物抗毒素，具有抗癌、化学预防、抗增殖和抗真菌活性。
TQ0160	Hydrastine 北美黄连碱,(-)-β-Hydrastine,(1R,9S)-β-Hydrastine	Others	Others
	Hydrastine ((-)-β-Hydrastine) 是一种天然生物碱，存在于Hydrastis canadensis 和Ranunculaceae 家族其他植物。
T3S1892	Crassicauline A 粗茎乌头碱甲,Crassicauline I	Others	Others
	Crassicauline A (Crassicauline I) 是一种乌头根中具有生物活性的生物碱。它对赤拟谷盗成虫具有拒食剂作用，其 EC50=1134.5 ppm。
T5514	Epibrassinolide 24-Epibrassinolide,B1105,表油菜素内酯,BP55	Apoptosis	Apoptosis
	Epibrassinolide (BP55) 是一种广泛存在的植物生长激素，具有缓解植物重金属和农药胁迫潜力。它在各种癌细胞中是一种潜在的凋亡诱导剂。
TN3051	4-Methoxyglucobrassicin	Others	Others
	4-Methoxyglucobrassicin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3051，CAS号为 83327-21-3。
TN4925	Rubiprasin B	Others	Others
	Rubiprasin B is a natural product from Rubia cordifolia var. pratensis.
TN4924	Rubiprasin A	Others	Others
	Rubiprasin A is a natural product from Rubia cordifolia var. pratensis.
TN6191	Murrastinine C
	Murrastinine C 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6191，CAS号为 20105-20-8。
T28415	Picrasidine N Picrasidine-N,PicrasidineN
	Picrasidine N is a naturally occurring dimeric alkaloid and a PPARβ/δ agonist.
T1607	Hydrastinine hydrochloride 北美黄连碱分碱盐酸盐,北美黄连碱分碱	Others	Others
	Hydrastinine hydrochloride 是金印草中的一种主要生物碱成分，可用作止血剂。
TN2597	12-Hydroxy-6-epi-albrassitriol	Others	Others
	12-Hydroxy-6-epi-albrassitriol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2597，CAS号为 178330-78-4。
T24638	Picrasidine M
	Picrasidine M is a PARP-1 inhibitor.
TN3270	(R)-3β-Hydroxy steroid sulfotransferase-IN-11	Others	Others

TN6651	Picrasidine Q
	Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.
TN4785	Picrasidine I	NF-κB; ROS; MAPK	Immunology/Inflammation; MAPK; NF-κB
	Picrasidine I has antiosteoclastogenic effect by inhibiting inflammation induced activation of MAPKs, NF-ÎºB and ROS generation followed by suppressing the gene expression of c-Fos and NFATc1 in osteoclast precursors.
T82822	Brassicanate A sulfoxide
	Brassicanate A sulfoxide 表现出除草效果，它能抑制植物中必需氨基酸的生物合成路径。该化合物通过结合并抑制多种酶的活性来发挥其作用，包括二羟酸脱水酶 (DHAD)、羟甲基丙酮酸双加氧酶 (HPPD)、乙酰乳酸合酶 (ALS)、PYL家族蛋白及转运抑制剂响应 1 (TIR1)。Brassicanate A sulfoxide 可以从甘蓝 (Brassica oleracea) 中提取获得。
TN5387	Grasshopper ketone	ERK; p38 MAPK; NO Synthase; JNK	Immunology/Inflammation; MAPK
	Grasshopper ketone 是从褐藻马尾藻中分离的化合物，是 RAW 264.7 细胞中 LPS 诱导的 NO 产生的有效抑制剂，通过抑制 MAPK（ERK，JNK 和 p38）和 NF-κB p65磷酸化来诱导抗炎作用。
TN3593	Carasiphenol C	Others	Others
	Carasiphenol C is a natural product from Carex humilis Leyss.
TN3591	Carasinol B	Others	Others
	Carasinol B is a natural product from Carex humilis Leyss.
TN4787	Picrasin B	Others	Others
	Picrasin B shows a significant clastogenic activity in cell cultures of Don lung cells of Chinese hamster.
TN3592	Carasinol D	Others	Others
	Carasinol D is a natural product from Carex humilis Leyss.
TN4636	Neoglucobrassicin	Others	Others
	Neoglucobrassicin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4636，CAS号为 5187-84-8。
T27281	Eritoran Tetrasodium B 1287,E 5564,B-1287,E5564,B1287,E-5564
	Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes.
T2S0799	Noroxyhydrastinine	Tyrosinase	Proteases/Proteasome
	Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 melanoma cells.
T13082	Tarasaponin VI	Others	Others
	Tarasaponin VI 是从 Aralia elata 中分离出来的，对乙醇吸收具有有效的抑制活性。
T75767	Parasin I TFA
	Parasin I (TFA) 是一种含有19个氨基酸残基的多肽，源自鲶鱼皮肤中分离出的组蛋白H2A，具备抗菌功能。
T21577	Narasin (sodium salt) Naracin sodium salt,naransin sodium,海南霉素,HainanMycin	NF-κB	NF-κB
	Narasin (sodium salt) (HainanMycin) 通过神经胶质瘤细胞中的 ER 应激诱导肿瘤坏死因子相关凋亡诱导配体 (TRAIL) 介导的细胞凋亡，并通过抑制 IκBα 的磷酸化来抑制 NF-κB 信号传导。
TN4441	Linderaspirone A	Others	Others
	Linderaspirone A shows significant activity against glucosamine-inducedinsulin resistance.
T40758	Hydrastinine
	Hydrastinine, a key alkaloid component found in Hydrastis canadensis (goldenseal), serves as an effective hemostatic agent.
T82304	Glucobrassicanapin potassium 4-Pentenylglucosinolate potassium
	Glucobrassicanapin (4-Pentenylglucosinolate) potassium 是脂肪族硫代葡萄糖苷类化合物，主要存在于白菜等蔬菜作物中。
TN3373	Albrassitriol	Others	Others
	Albrassitriol is a natural product from the cultures of the fungus Penicillium sp.
TN1796	Brassicin 油菜,Isorhamnetin 7-O-glucoside	Others	Others
	Isorhamnetin 7-O-glucoside has antioxidant activity, it showed the peroxynitrite and DPPH scavenging activities with IC50 values of 2.07 /- 0.17 and 13.3 microM, respectively.
TN3163	6-epi-Albrassitriol	Others	Others
	6-epi-Albrassitriol is a natural product from A spergillussp.
TN3717	Crassanine	Others	Others
	Crassanine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3717，CAS号为 16790-92-4。
T25596	Lactiflorasyne
	Lactiflorasyne is a bioactive chemical from Artemisia lactiflora Wall that contains an ester group, a spiro system and two triple bonds.
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天然产物

Methylophiopogonanone B

Cat.No: T5S1261

Target: Ras

Phellodendrine chloride

Cat.No: T5S0777

Target: Others

Eicosapentaenoic Acid

Cat.No: T5368

Target: Histone Demethylase, Others, Endogenous Metabolite

Cat.No: TQ0165

Synonym: 阿格拉宾,(+)-Arglabin

Target: NOD-like Receptor (NLR), Transferase, NOD, Autophagy

Cat.No: TN1413

Synonym: 荔枝素，巴美灵,荔枝素

Target: Endogenous Metabolite, NO Synthase, Ras

Antineoplaston A10

Cat.No: T7131

Synonym: 3-苯基乙酰氨基-2,6-哌啶二酮,NSC-648539

Target: Apoptosis, Endogenous Metabolite, Ras

Raspberry ketone glucoside

Cat.No: T8244

Synonym: 覆盆子酮葡糖苷,树莓苷，覆盆子酮葡萄糖甙

Target: Others

(22S,23S)-Homobrassinolide

Cat.No: T41372

Synonym: 油菜素内酯,SSHB

Target: Others

Cat.No: T15753

Synonym: Licuraside

Target: Tyrosinase

Dryocrassin ABBA

Cat.No: T4S1114

Synonym: 东北贯众素,Dryocrassin

Target: Influenza Virus, Antibacterial

Hederasaponin B

Cat.No: T3345

Synonym: 常春藤皂苷B,Eleutheroside M,刺五加叶中,Hederacoside B

Target: Others, Virus Protease

Sinocrassoside C1

Cat.No: TN7077

Target: Others

(Rac)-Brassinazole

Cat.No: T7132

Synonym: BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑

Target: P450

Raspberry ketone

Cat.No: T2S0633

Synonym: Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone,覆盆子酮

Target: PPAR

Cat.No: T3151

Synonym: Brassin lactone,24-Epibrassinolide,芸苔素内酯

Target: Apoptosis, Others

Cat.No: T4373

Synonym: BSN,芸苔宁

Target: Antifungal

Cat.No: TQ0160

Synonym: 北美黄连碱,(-)-β-Hydrastine,(1R,9S)-β-Hydrastine

Target: Others

Crassicauline A

Cat.No: T3S1892

Synonym: 粗茎乌头碱甲,Crassicauline I

Target: Others

Epibrassinolide

Cat.No: T5514

Synonym: 24-Epibrassinolide,B1105,表油菜素内酯,BP55

Target: Apoptosis

4-Methoxyglucobrassicin

Cat.No: TN3051

Target: Others

Cat.No: TN4925

Target: Others

Cat.No: TN4924

Target: Others

Cat.No: TN6191

Cat.No: T28415

Synonym: Picrasidine-N,PicrasidineN

Hydrastinine hydrochloride

Cat.No: T1607

Synonym: 北美黄连碱分碱盐酸盐,北美黄连碱分碱

Target: Others

12-Hydroxy-6-epi-albrassitriol

Cat.No: TN2597

Target: Others

Cat.No: T24638

(R)-3β-Hydroxy steroid sulfotransferase-IN-11

Cat.No: TN3270

Target: Others

Cat.No: TN6651

Cat.No: TN4785

Target: NF-κB, ROS, MAPK

Brassicanate A sulfoxide

Cat.No: T82822

Grasshopper ketone

Cat.No: TN5387

Target: ERK, p38 MAPK, NO Synthase, JNK

Cat.No: TN3593

Target: Others

Cat.No: TN3591

Target: Others

Cat.No: TN4787

Target: Others

Cat.No: TN3592

Target: Others

Neoglucobrassicin

Cat.No: TN4636

Target: Others

Eritoran Tetrasodium

Cat.No: T27281

Synonym: B 1287,E 5564,B-1287,E5564,B1287,E-5564

Noroxyhydrastinine

Cat.No: T2S0799

Target: Tyrosinase

Cat.No: T13082

Target: Others

Cat.No: T75767

Narasin (sodium salt)

Cat.No: T21577

Synonym: Naracin sodium salt,naransin sodium,海南霉素,HainanMycin

Target: NF-κB

Linderaspirone A

Cat.No: TN4441

Target: Others

Cat.No: T40758

Glucobrassicanapin potassium

Cat.No: T82304

Synonym: 4-Pentenylglucosinolate potassium

Cat.No: TN3373

Target: Others

Cat.No: TN1796

Synonym: 油菜,Isorhamnetin 7-O-glucoside

Target: Others

6-epi-Albrassitriol

Cat.No: TN3163

Target: Others

Cat.No: TN3717

Target: Others

Cat.No: T25596

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