101
1
60
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0134 |
p53 inhibitor/reactivator kit
p53 inhibitor/reactivator kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1496L |
p5 Ligand for Dnak and DnaJ acetate
p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base) |
HSP | Cytoskeletal Signaling; Metabolism |
p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base) 是一种九肽。它是 DnaK(大肠杆菌 Hsp70)和 DnaJ(大肠杆菌 Hsp40)的高亲和力配体。 | |||
T22277 |
BMS-P5
|
PAD | Chromatin/Epigenetic |
BMS-P5 是一种特异性具有口服活性的肽精氨酸二亚胺酶 4抑制剂。它可阻断多发性骨髓瘤诱导的 NET 形成,并延缓肿瘤进程。 | |||
T22277L |
BMS-P5 free base
|
PAD | Chromatin/Epigenetic |
BMS-P5 free base 是一种特异性,可口服的肽精氨酸二亚胺酶抑制剂,可阻断多发性骨髓瘤诱导的 NET 形成,并延缓肿瘤进程。 | |||
TP1496 |
p5 Ligand for Dnak and DnaJ
|
||
p5 Ligand for Dnak and DnaJ is a non-apeptide and correspond to the main binding sites of the 23 residues of the mitochondrial aspartate aminotransferase presequence.P5 ligand is a high affinity ligand for Dnak and DnaJ. | |||
T80447 |
Pardaxin P5
|
||
Pardaxin P5,一种抗菌肽,其对大肠杆菌的最小抑制浓度(MIC)为13 μM。 | |||
T69110 |
Aseanostatin P5
|
||
Aseanostatin P5 inhibits myeloperoxidase (MPO) release from human polymorphonuclear leukocytes. | |||
T79877 |
MTvkPABC-P5
|
||
MTvkPABC-P5d,作为TLR7激动剂,属于免疫刺激剂类。该化合物主要应用于合成免疫刺激抗体偶联物(ISAC)。 | |||
T24055 |
FAUC 213
FAUC213,FAUC-213 |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
FAUC 213 是一种具有口服活性的‘、高度选择性的、可透过血脑屏障的多巴胺 D4受体完全拮抗剂,对 hD4.4的 Ki=2.2 nM。它对 D2和 D3受体的活性较低,对于 hD2、hD3的 Ki 分别为 3.4 μM、5.3 μM。它表现出非典型的抗精神病活性。 | |||
T24584 |
P505-15 Acetate
PRT 062607 Acetate,P505 15 Acetate,PRT-062607 Acetate,PRT062607 Acetate,P50515 Acetate |
Tyrosinase | Proteases/Proteasome |
P505-15 Acetate 是脾脏酪氨酸激酶的选择性抑制剂,通过抑制白细胞免疫功能和炎症起作用,导致关节炎评分降低和组织学损伤减轻。 | |||
T16294 |
NGP555
|
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
NGP555 是 γ-分泌酶调节剂。 | |||
T10782 |
CGP52411
DAPH |
EGFR; Beta Amyloid | Angiogenesis; JAK/STAT signaling; Neuroscience; Tyrosine Kinase/Adaptors |
CGP52411 是一种具有口服活性的 ATP 竞争性 EGFR 抑制剂(IC50:0.3 μM)。 CGP52411 阻止 Ca2+ 离子有毒流入神经元细胞,并显着抑制和逆转 β-淀粉样蛋白 Aβ42 原纤维聚集体的形成。 CGP52411 可用于阿尔茨海默病的研究。 | |||
T8351 |
UBP551
3,5-二羟基-2-萘酸 |
NMDAR | Neuroscience |
UBP551 是一种有效的选择性 NMDA 受体调节剂。 | |||
T72026 |
p53-MDM2-IN-1
|
Mdm2; p53 | Apoptosis |
p53-MDM2-IN-1 (Example 30) 是一种 p53-MDM2/X 蛋白相互作用的抑制剂,Ki 值为 23.35 µM。p53-MDM2-IN-1 能用于抗肿瘤研究。 | |||
T13824 |
PP58
|
FGFR; p38 MAPK; TNF; PDGFR; Src | Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors |
PP58 是 PDGFR、FGFR 和 Src 家族的抑制剂。 | |||
T13336 |
VTP50469
|
Apoptosis; Epigenetic Reader Domain; Histone Methyltransferase | Apoptosis; Chromatin/Epigenetic |
VTP50469 是一种高选择性和口服活性的Menin-MLL 相互作用抑制剂,具有有效的抗白血病活性,Ki 为 104 pM。 | |||
T67972L |
Amp579 TFA
Amp579 TFA(213453-89-5 Free base) |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Amp579 TFA 是一种新型 腺苷 A1/A2a 受体激动剂 ,诱导针对体内心肌休克的急性和延迟预处理。 | |||
T67698 |
p53-Mdm2 inhibitor 4
|
Mdm2; p53 | Apoptosis |
p53-Mdm2 inhibitor 4 抑制 p53-MDM2 蛋白质-蛋白质相互作用。 | |||
T60839 |
SLMP53-1
|
p53 | Apoptosis |
SLMP53-1 是一种 p53 激活剂, 具有抗肿瘤活性,抑制 wt 和 mutp53,激活异种移植人肿瘤组织中葡萄糖代谢的重编程,干扰血管生成和迁移。SLMP53-1 抑制肿瘤细胞生长,可用于研究人直肠癌。 | |||
T7301 |
BDP5290
|
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
BDP5290 是一种有效 ROCK 和 MRCK 抑制剂,对 ROCK1、ROCK2、MRCKα 和 MRCKβ 的 IC50 分别为 5、50 、10 和 100 nM。 | |||
T60130 |
USP5-IN-1
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
USP5-IN-1 (compound 64) 是一种有效的去泛素酶USP5抑制剂,与 USP5 ZnF UBD 结合,KD 值为 2.8 μM。USP5-IN-1对九种含有结构相似的 ZnF UBD 结构域的蛋白质具有选择性。USP5-IN-1 抑制 USP5 对双泛素底物的催化裂解。 | |||
T22733 |
DL-AP5
DL-2-氨基-5-膦酰基缬草酸 |
NMDAR | Neuroscience |
DL-AP5 是选择性 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂的外消旋形式,具有抗惊厥作用。 | |||
T10930 |
D-AP5
(R)-(-)-2-氨基-5-膦酰戊酸,D-APV,D-2-Amino-5-phosphonovaleric acid |
NMDAR; iGluR | Membrane transporter/Ion channel; Neuroscience |
D-AP5 (D-APV) 是一种选择性和竞争性NMDA 受体拮抗剂,Kd 为 1.4 μM。D-AP5 抑制 NMDA 受体的谷氨酸结合位点。 | |||
T5473 |
ASP5878
ASP-5878 |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
ASP5878 是一种 FGFR 1 (IC50:0.47 nM)、FGFR 2 (IC50:0.6 nM)、FGFR 3 (IC50:0.74 nM)、和 FGFR 4 (IC50:3.5 nM)的抑制剂,具有口服活性,具有潜在的抗肿瘤作用。 | |||
T72771 |
p53 Activator 7
|
Apoptosis | Apoptosis |
p53 Activator 7 是一种高效性和细胞渗透性的 p53 突变 Y220C (MDM-2/p53) 激活剂,可诱导细胞凋亡 。 | |||
T81417 |
PP5-IN-1
|
Apoptosis; Phosphatase | Apoptosis; Metabolism |
PP5-IN-1 是一种具有有效性和竞争性的丝氨酸/苏氨酸蛋白磷酸酶-5 (PP5) 抑制剂,具有潜在的抗癌活性,可诱导癌细胞凋亡。 | |||
T16831 |
(S)-SNAP5114
|
Others; GABA Receptor | Membrane transporter/Ion channel; Neuroscience; Others |
(S)-SNAP5114 是一种选择性的 GABA 转运抑制剂,对 hGAT-3 的 IC50 为 5 μM,对 rGAT-2 的 IC50 为 21 μM。 (S)-SNAP5114 具有抗惊厥性质。 | |||
T41068 |
P53R3
|
p53 | Apoptosis |
P53R3是一种有效的 p53再激活剂。P53R3可恢复 p53热点突变体的序列特异性 DNA 结合,包括p53 R175H、p53 R248W 和p53 R273H。P53R3特异性诱导p53依赖性抗增殖作用,其特异性比PRIMA-1高得多的。P53R3增强野生型p53和p53 M237I 向靶基因启动子的募集。P53R3强烈增强死亡受体死亡受体5(DR5)的mRNA、总蛋白和细胞表面的水平。P53R3用于癌症研究。 | |||
TP1427L |
ReACp53 acetate
|
p53 | Apoptosis |
ReACp53 acetate 能够抑制 p53 amyloid 的形成, 挽救 p53 在癌细胞中的作用。 | |||
T4363 |
CGP52432
4-苄氧基苯基异硫氰酸酯,CGP 52432 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
CGP52432 是一种GABAB 受体拮抗剂,IC50值为 85 nM。 | |||
T40685L |
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (600171-70-8 Free base) |
Others | Others |
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (Orphan GPCR SP9155 agonist P550 ) 是具有促食欲作用的 RFamide 肽家族的成员。 | |||
T63438 | rel-MDM2/4-p53-IN-3 | ||
rel-MDM2/4-p53-IN-3 是 MDM2/4-p53 蛋白质-蛋白质相互作用 (PPI) 抑制剂,能够作用于MDM2-p53、MDM4-p53,其IC50值分别为18.5 nM、14.8 nM。rel-MDM2/4-p53-IN-3 能够用于研究癌症,如结肠癌。 | |||
T70878 | P516-0475 | ||
P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO. This compound induces quorum sensing by stabilizing SHP pheromones in culture. | |||
T76228 |
ASP5286
|
||
ASP5286 是一种新型的非免疫 cyclophilin 抑制剂,用于研究 HCV。 | |||
TP2281 |
p53 tumor suppressor fragment
|
Others | Others |
p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where i | |||
T79739 |
CYP51/PD-L1-IN-2
|
||
CYP51/PD-L1-IN-2(compound L20)是一种具有抗真菌活性的喹唑啉化合物。它作为CYP51(IC50:0.263 μM)和PD-L1(IC50:0.017 μM)的双重抑制剂,能够在细胞周期的早期引发真菌细胞凋亡。CYP51/PD-L1-IN-2进一步显著降低IL-2、NLRP3、NF-κBp65等蛋白水平,触发线粒体损伤及ROS积累,终致真菌细胞裂解和死亡。 | |||
T61369 |
p53 Activator 2
|
||
p53 Activator 2 (compound 10ah) 插入DNA,导致显著的DNA双链断裂。该化合物通过增加p53、p-p53、CDK4、p21的表达,使细胞周期在G2/M期停滞,诱导细胞凋亡,并显著降低抗凋亡蛋白Bcl-2、Bcl-xL和cyclin B1的水平。此外,p53 Activator 2表现出对MGC-803细胞的抗增殖效果,其IC50为1.73 μM,且在MGC-803异种移植肿瘤模型中展示出有效的抗癌活性。 | |||
T69846 |
VTP50469 mesylate
|
||
VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations. | |||
T24440 |
MDM2-p53-IN-1b
MDM2-p53 inhibitor 1b,MDM2 p53 IN 1b |
||
MDM2-p53-IN-1b is the MDM2-p53 interaction inhibitor. | |||
T10875 |
CP5V
|
Others | Others |
CP5V, a PROTAC, induces mitotic inhibition, and suppresses cancer cell proliferation. It specifically degrades Cdc20 by linking Cdc20 to the VHL/VBC complex for ubiquitination followed by proteasomal degradation. | |||
T24736 |
RP5063 Hydrochloride
RP-5063 HCl,RP 5063 HCl,RP 5063 Hydrochloride,RP-5063 Hydrochloride,RP5063 HCl |
||
RP5063 Hydrochloride is a modulator of multimodal serotonin receptors. | |||
T13336L |
VTP50469 fumarate
|
Others | Others |
VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity. | |||
T22732 |
DL-AP5 Sodium salt
|
Others | Others |
DL-AP5 Sodium salt is a NMDA receptor antagonist. | |||
T22909 |
L-AP5
|
Others | Others |
L-AP5 is a NMDA antagonist. | |||
T69052 | P552-02 free base | ||
P552-02, also known as KM-003, PS 552-02, or 552-02, is a sodium channel blocker potentially for the treatment of cystic fibrosis. | |||
T62041 | XP5 | ||
XP5 是一种有效的、具有口服活性的HDAC6抑制剂(IC50= 31 nM)。XP5高效抑制各种癌细胞系(包括抗 HDACi 的 YCC3/7 胃癌细胞)的增殖 (IC50=0.16-2.31 μM)。 | |||
T64079 | Mutant p53 modulator-1 | ||
Mutant p53 modulator-1 是一种突变型 p53 调节剂。Mutant p53 modulator-1 能够阻碍含有 p53 突变的癌症的进展。 | |||
T80132 |
CBP501 Affinity Peptide
|
||
CBP501 Affinity Peptide为Chk激酶抑制剂,具有消除DNA损伤剂诱导的G2停滞作用,主要应用于癌症研究领域。 | |||
TP2164 |
TP508 TFA (121341-81-9 free base)
TP508 TFA |
Others | Others |
TP508 TFA is a nonproteolytic thrombin peptide. TP508 TFA activates endothelial NO synthase (eNOS) and stimulates the production of NO in human endothelial cells. It activates endothelial cells and stem cells to revascularize and regenerates tissues. | |||
TP1853 |
TP508
|
||
TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibroblasts.TP508 (Chrysalin) is an investi | |||
TP2299 |
tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]
|
Others | Others |
Tumor protein p53 binding protein (53BP1) has been identified in a yeast two-hybrid screen as a protein that interacts with the central DNA–binding domain of p532. Similar to breast cancer susceptibility gene 13, 4 (BRCA1; 53BP1 enhances p53-dependent tra |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01124 |
PDIA6 Protein, Human, Recombinant (His)
Thioredoxin Domain-Containing Protein 7,P5,ERP5... |
Human | Human Cells |
Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. The PDIA6 expressed in platelets, its functions as a chaperone that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA... | |||
TMPY-05325 |
Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His)
exosome component 9,p5,p6,PMSCL1,Rrp45p,RRP45,PM/Sc... |
Human | Baculovirus-Insect Cells |
Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 51.3 kDa. Accession number: Q06265-1 | |||
TMPH-00782 |
OMP P5 Protein, Haemophilus influenzae, Recombinant (His & Myc & SUMO)
|
Haemophilus influenzae | E. coli |
Acts as a fimbriae subunit, allowing adhesion to host cells.; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | |||
TMPY-02893 |
NT5C3A/NT5C3 Protein, Human, Recombinant
P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,U... |
Human | E. coli |
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but... | |||
TMPY-02955 |
CABP5 Protein, Human, Recombinant (His)
calcium binding protein 5,CABP3 |
Human | E. coli |
CABP3, also known as CABP5, belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of CABP3 gene is retina-specific. The mouse homolog of CABP3 has been shown to express in the inner nuclear layer of the retina, suggested its role in neuronal functioning. The specific function of CABP3 gene is unknown. Study of the transcripts and genomic structure r... | |||
TMPJ-01063 |
RBP5 Protein, Human, Recombinant
Retinol-binding protein 5,CRBP-III,Cellular retinol-binding ... |
Human | E. coli |
Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol. Retinol and retinoic acid play crucial roles in the modulation of gene expression and overall development of an embryo. However, deficit or excess of either one of these substances can cause early embryo mortality or developmental malformations. Regulation of transport and metabolism of retinol necessary for a successful pregnancy is accomplished via RBP. Retinol binding p... | |||
TMPY-02527 |
p53R2 Protein, Human, Recombinant (His)
P53R2,MTDPS8A,MTDPS8B,ribonucleotide reductase M2 B... |
Human | E. coli |
Ribonucleoside reductase subunit M2B, also known as RRM2B or p53R2, is an enzyme belonging to the iron-dependent ribonucleotide reductase (RNR) enzyme family which is essential for DNA synthesis. Ribonucleotide reductase (RNR) is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides and plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair. RRM2B is a phospho... | |||
TMPY-03052 |
MFAP5 Protein, Human, Recombinant (His)
microfibrillar associated protein 5,MFAP-5,AAT9,MAGP2,MP25,M... |
Human | HEK293 |
MFAP5 (Microfibril Associated Protein 5, also known as MAGP2) is a Protein Coding gene. MFAP5 is a component of the elastin-associated microfibrils. It belongs to the MFAP family. As a 25-kD microfibril-associated glycoprotein, MFAP5 is rich in serine and threonine residues. It stimulates the assembly of elastic fibers, a complex structure composed of a tropoelastin inner core and microfibril outer mantle comprising proteins such as fibrillins and microfibril-associated glycoproteins that guide ... | |||
TMPH-00964 |
ATP5PB Protein, Human, Recombinant (His & Myc)
ATP synthase proton-transporting mitochondrial F(0) complex ... |
Human | E. coli |
ATP5PB Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02097 |
PPP5C Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
PPP5C Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02888 |
SFRP5 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. | |||
TMPH-00966 |
ATP5F1B Protein, Human, Recombinant (His)
ATP synthase F1 subunit beta,ATP synthase subunit beta, mito... |
Human | Yeast |
ATP5F1B Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPH-03017 |
CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Cytochrome P450-14DM,Sterol 14alpha-demethylase,Sterol 14-al... |
Mycobacterium tuberculosis | Baculovirus |
Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | |||
TMPH-00058 |
asFP595 Protein, Anemonia sulcata, Recombinant (hFc)
GFP-like non-fluorescent chromoprotein FP595,asF |
Anemonia sulcata | HEK293 |
Pigment protein that is intensely purple in color. | |||
TMPH-02574 |
p53 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 ex... | |||
TMPK-01509 |
HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi)
TRP53,HLA-A,TP53,LFS1,P53,MHC,FLJ... |
Human | HEK293 |
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. | |||
TMPK-01437 |
HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
FLJ92943,HLA-A,TP53,Antigen NY-CO-13,TRP53... |
Human | HEK293 |
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. | |||
TMPK-01532 |
HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)
Antigen NY-CO-13,BCC7,FLJ92943,HLA-A,LFS1,P53,T... |
Human | HEK293 |
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. | |||
TMPK-01538 |
HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
MHC,LFS1,Antigen NY-CO-13,HLA-A,BCC7,TP53,TRP5<... |
Human | HEK293 |
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. | |||
TMPK-01531 |
HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi)
Antigen NY-CO-13,MHC,FLJ92943,TRP53,HLA-A,BCC7,T |
Human | HEK293 |
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. | |||
TMPY-06004 |
SARS-CoV-2 Spike RBD Protein (P521R, His)
|
SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of... | |||
TMPK-00659 |
LAMP5 Protein, Cynomolgus, Recombinant (His)
C20orf103,BAD-LAMP,BADLAMP,LAMP-5,UNC-43,dJ1119D9.3 |
Cynomolgus | HEK293 |
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. In the mouse forebrain, LAMP5 is expressed in a subpopulation of GABAergic neurons in the olfactory bulb and the striato-nigral system, where it is required for fine-tuning of GABAergic synaptic transmission. | |||
TMPY-04025 |
CEP57 Protein, Human, Recombinant (GST)
MVA2,PIG8,TSP57,centrosomal protein 57kDa |
Human | E. coli |
CEP57 is a centrosomal protein and is involved in nucleating and stabilizing microtubules. CEP57 was initially identified as a regulator of centriole overduplication in an RNA interference screen. There is a link between altered microenvironmental signaling cues such as FGF-2 overexpression and mitotic instability and provide a rationale for the therapeutic targeting of the FGF-2/FGFR1/CEP57 axis in prostate cancer. CEP57 is involved in intracellular transport processes, and its overexpression c... | |||
TMPK-00957 |
MFAP5 Protein, Human, Recombinant (hFc)
MAGP2,AAT9,MAGP-2,MP25,MFAP-5 |
Human | HEK293 |
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. | |||
TMPY-02228 |
p53 Protein, Cynomolgus, Recombinant
tumor protein p53,p53,TP53 |
Cynomolgus | E. coli |
p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family. It contains transcription activation, DNA-binding, and oligomerization domains. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 (TP53) is a transcription factor whose protein levels and post-translational modification state alter in response to cellular stress (such as DNA damag... | |||
TMPY-02211 |
USP5 Protein, Human, Recombinant (His)
ISOT,ubiquitin specific peptidase 5 (isopeptidase T) |
Human | Baculovirus-Insect Cells |
Ubiquitin carboxyl-terminal hydrolase 5, also known as Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thiolesterase 5, Ubiquitin-specific-processing protease 5, ISOT and USP5, is a member of the peptidase C19 family. USP5 contains 2 UBA domains and one UBP-type zinc finger. The UBP-type zinc finger domain interacts selectively with an unmodified C-terminus of the proximal ubiquitin. Both UBA domains are involved in polyubiquitin recognition. The UBP-type zinc finger domain crystallizes as ... | |||
TMPY-04076 |
RBP5 Protein, Human, Recombinant (His)
CRBPIII,retinol binding protein 5,CRBP3,RBP5,CRBP-I... |
Human | E. coli |
RBP5 Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 18.2 kDa. Accession number: P82980 | |||
TMPK-01442 |
HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
HLA-A,P53,TP53,LFS1,MHC,BCC7,TRP5... |
Human | HEK293 |
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. | |||
TMPY-05975 |
SARS-CoV-2 Spike RBD Protein (P521S, His)
|
SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of... | |||
TMPY-00960 |
ACP5 Protein, Human, Recombinant (His)
acid phosphatase 5, tartrate resistant,TRAP,SPENCDI |
Human | HEK293 |
Tartrate-resistant acid phosphatase (TRACP) or acid phosphatase 5, tartrate resistant (ACP5 or TRAP) is a glycosylated monomeric metalloenzyme expressed in mammals. TRACP is associated with osteoblast migration to bone resorption sites, and, once there, TRACP is believed to initiate osteoblast differentiation, activation, and proliferation. TRACP once considered to be just a histochemical marker of osteoclasts is now recognised to be a molecule of widespread occurrence with functions in both the... | |||
TMPK-01161 |
LAMP5 Protein, Mouse, Recombinant (hFc)
C20orf103,BADLAMP,dJ1119D9.3,LAMP-5,UNC-43,BAD-LAMP |
Mouse | HEK293 |
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. LAMP5 deficiency led to a larger intensity-dependent increase of wave I, II and V peak amplitude of auditory brainstem response. LAMP5 plays a pivotal role in sensorimotor processing in the brainstem and spinal cord. | |||
TMPK-01234 |
LAMP5 Protein, Human, Recombinant (His)
BAD-LAMP,BADLAMP,C20orf103,UNC-43,dJ1119D9.3,LAMP-5 |
Human | HEK293 |
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. LAMP5 deficiency led to a larger intensity-dependent increase of wave I, II and V peak amplitude of auditory brainstem response. LAMP5 plays a pivotal role in sensorimotor processing in the brainstem and spinal cord. | |||
TMPY-05896 |
Influenza A H3N2 (A/swine/Thailand/CU-P53/2012) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ... | |||
TMPH-01982 |
RPS10P5 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
RPS10P5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-03525 |
Cap5A Protein, S. aureus, Recombinant (His)
Capsular polysaccharide type 5 biosynthesis protein cap5... |
Staphylococcus aureus | in vitro E. coli expression system |
Required for the biosynthesis of type 5 capsular polysaccharide (Cap5/CP5). Might act as the chain-length regulator. | |||
TMPH-00057 |
asFP595 Protein, Anemonia sulcata, Recombinant (GST)
GFP-like non-fluorescent chromoprotein FP595,asF |
Anemonia sulcata | E. coli |
Pigment protein that is intensely purple in color. | |||
TMPH-00969 |
ATP5O Protein, Human, Recombinant (GST)
OSCP,ATP5PO,ATP synthase peripheral stalk subunit O... |
Human | E. coli |
ATP5O Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPY-05327 |
SRP54 Protein, Human, Recombinant (His)
|
Human | Baculovirus-Insect Cells |
SRP54 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 58 kDa. Accession number: P61011-1 | |||
TMPY-04150 |
HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)
Gag-Pol |
HIV | E. coli |
HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) is expressed in E. coli with His tag. The predicted molecular weight is 53.6 kDa. Accession number: P04585 | |||
TMPK-01508 |
HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)
TP53,Antigen NY-CO-13,P53,MHC,HLA-A,BCC7,L... |
Human | HEK293 |
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. | |||
TMPY-02880 |
ENPP5 Protein, Human, Recombinant (His)
NPP-5,ectonucleotide pyrophosphatase/phosphodiesterase 5 (pu... |
Human | HEK293 |
ENPP5 is a member of the nucleotide pyrophosphatase/phosphodiesterase family (NPP). It is a family comprised of dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. There are seven isoforms in NPP family, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. NPP also belongs to the alkaline phosphatase (AP) superfamily of enzymes and they are located in the cell membra... | |||
TMPY-02174 |
FABP5 Protein, Human, Recombinant
PA-FABP,E-FABP,fatty acid binding protein 5 (psoriasis-assoc... |
Human | E. coli |
Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is pre... | |||
TMPY-03609 |
ATP5D Protein, Human, Recombinant (His)
ATP synthase, H+ transporting, mitochondrial F1 complex, del... |
Human | E. coli |
ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase consists of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon... | |||
TMPK-01233 |
LAMP5 Protein, Human, Recombinant (hFc)
BADLAMP,C20orf103,LAMP-5,dJ1119D9.3,UNC-43,BAD-LAMP |
Human | HEK293 |
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. In the mouse forebrain, LAMP5 is expressed in a subpopulation of GABAergic neurons in the olfactory bulb and the striato-nigral system, where it is required for fine-tuning of GABAergic synaptic transmission. | |||
TMPH-00968 |
ATP5C1 Protein, Human, Recombinant (His & Myc)
F-ATPase gamma subunit,ATP5C1,ATP5CL1,ATP ... |
Human | E. coli |
ATP5C1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-03249 |
ATP5F1B Protein, Rat, Recombinant (His & Myc)
ATPMB,ATPSB,ATP synthase subunit beta, mitochondrial,ATP syn... |
Rat | E. coli |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain ... | |||
TMPH-00954 |
Aquaporin-5/AQP5 Protein, Human, Recombinant (His)
Aquaporin-5,AQP5,AQP-5 |
Human | in vitro E. coli expression system |
Aquaporin-5/AQP5 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system. | |||
TMPH-00965 |
ATP5F1A Protein, Human, Recombinant (His)
ATP5F1A,ATP5A,ATP synthase subunit alpha, ... |
Human | E. coli |
ATP5F1A Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-03489 |
SARS-CoV-2 3C-like proteinase NSP5 Protein (His)
|
SARS-CoV-2 | E. coli |
SARS-CoV-2 3C-like proteinase NSP5 Protein (His) is expressed in E. coli with N-terminal 10xHis tag. The predicted molecular weight is 39.8 kDa. Accession number: YP_009725301.1 | |||
TMPK-01552 |
HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TP53,TRP53,HLA-A,MHC,Antigen NY-CO-13,BCC7... |
Human | HEK293 |
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. | |||
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