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Search Results for " oxa "

792

抑制剂 & 化合物

56

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1973L	OXA (17-33) acetate	OX Receptor	GPCR/G Protein; Neuroscience
	OXA (17-33) acetate 是一种比 OX2 (EC50 = 187 nM) 更有效的 orexin-1 受体 (OX1, EC50 = 8.29 nM)) 激动剂。
T28277	OXA-11 OXA 11
	OXA-11 is a potent inhibitor of focal adhesion kinase (FAK) with anti-tumor activity.
TP1973	OXA(17-33) OXA (17-33)
	Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.
T21816	OXA-01
	OXA-01 是有效的mTORC1和mTORC2抑制剂，其IC50值分别为 29 nM 和 7 nM。OXA-01具有癌症治疗的潜力
T24574	OXA-06 Dihydrochloride
	OXA-06 Dihydrochloride is a PANC-1 cell migration and MYPT1 phosphorylation inhibitor.
T75922	OXA(17-33) TFA
	OXA(17-33) TFA，一种高效且选择性的orexin-1 receptor (OX1)激动剂，其对OX1 (EC50=8.29 nM) 的选择性是对OX2 (187 nM) 的23倍。
T60050	ANT3310	Antibacterial	Microbiology/Virology
	ANT3310 是一种广谱共价丝氨酸 β-内酰胺酶抑制剂，对 AmpC、CTX-M-15、TEM-1、OXA-48、OXA-23 和 KPC-2 的 IC50 范围为 1 nM 至 175 nM。 ANT3310 可用于细菌感染研究。
T74688	23-Oxa-OSW-1
	23-Oxa-OSW-1 是OSW 1 的衍生物，是一种有效的甾醇结合蛋白 (OSBP) 抑制剂。23-Oxa-OSW-1 具有抗肿瘤活性。
T9310	mTOR inhibitor 13	PI3K; mTOR	PI3K/Akt/mTOR signaling
	mTOR inhibitor 13是一种选择性的mTOR 抑制剂，对mTOR 和PI3Kα的IC50分别为0.29nM 和119nM。
T66929	2-Oxa-1,4-butanediol diacetate
	2-Oxa-1,4-butanediol diacetate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66929，CAS号为 59278-00-1。
T66969	Ethyl (1S,5R,6S)-5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate
	Ethyl (1S,5R,6S)-5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66969，CAS号为 204254-96-6。
T67700	1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea
	1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67700，CAS号为 1144075-47-7。
T66648	(6S,9S,12S)-Benzyl 12-benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate
	(6S,9S,12S)-Benzyl 12-benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate，产品编号为T66648，CAS号为868540-15-2，是一种在生命科学研究领域有用的有机化合物。
T9319	Tosufloxacin tosufloxacin tosilate,托氟沙星,Ozex,7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid	Others	Others
	Tosufloxacin (Ozex) 是一种喹诺酮类抗菌剂，是茶碱代谢的有效抑制剂。
T64325	(4S,5R)-3-tert-butoxycarbony-2-(4-anisy)-4-phenyl-5-oxazolidinecarboxylic acid	Others	Others
	(4S,5R)-3-tert-butoxycarbony-2-(4-anisy)-4-phenyl-5-oxazolidinecarboxylic acid 又名多烯紫杉醇侧链，作为一种医药中间体，主要用于合成药物多烯紫杉醇。
T3355	Naloxegol oxalate NKTR-118,NKTR-118 oxalate,AZ 13337019,AZ-13337019 oxalate	P450	Metabolism
	Naloxegol oxalate (NKTR-118) 是一种外周选择性 opioid 样物质拮抗剂，用于治疗 opioid 样物质引起的便秘。
T19805	Benoxacor BRN-4190275,解草酮,BRN 4190275,BRN4190275	Others	Others
	Benoxacor (BRN-4190275) 是一种惰性农业化学品。它作为一种除草剂安全剂，可保护作物免受除草剂毒性。
T77670	(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid	Somatostatin	GPCR/G Protein
	(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid 是一种潜在的SSTR4激动剂。
T1293	Gatifloxacin BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155,加替沙星	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Gatifloxacin (CG5501) 是一种具有广谱抗菌活性的氟喹诺酮类抗生素。它可抑制大肠杆菌 DNA 解旋酶 (IC50=0.109 μg/ml) 和细菌 II 型拓扑异构酶(IC50=13.8 μg/ml)。在动物模型中，它有抗细菌性结膜炎作用。
T12107	MRS-3777 hemioxalate	Adenosine Receptor	GPCR/G Protein; Neuroscience
	MRS-3777 hemioxalate 是一种选择性腺苷 A3 受体拮抗剂，可逆转其相应激动剂的抗伤害感受作用，可用于研究炎症性疼痛。
T50032	5-(2-furyl)-N-propylisoxazole-3-carboxamide	Others	Others
	5-(2-furyl)-N-propylisoxazole-3-carboxamide 是一种用作分子结构单元的化合物，被认为是 NMDA 受体的调节剂，已被证明对神经元细胞中谷氨酸诱导的兴奋性毒性和氧化应激具有保护作用。它也被发现具有抗炎活性，使其成为阿尔茨海默病和帕金森病等疾病的潜在治疗剂。
T50061	[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine	Others	Others
	[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine 是一种哌嗪衍生物，它是血清素和多巴胺受体的部分激动剂，使其成为治疗抑郁症和精神分裂症等精神疾病的候选药物。
T7865	Danofloxacin 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine	Others; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Danofloxacin (Danofloxacin free base) free base 是一种具有口服活性第三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶发挥抗菌作用。它可用于牛，猪和鸡呼吸道疾病的研究。
T20721	Isoxaflutole RP 201772,异恶唑草酮,Merlin,RP-201772,RP201772	Others	Others
	Isoxaflutole (RP-201772) 是一种低毒除草剂，已作为阿特拉津的替代品上市销售。
T22234	Alloxazine	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Alloxazine 是一种 A2 受体拮抗剂，其对 A2B 受体的选择性比对 A2A 受体的选择性高约 10 倍。
T21136	Fluxapyroxad	Antifungal	Microbiology/Virology
	Fluxapyroxad 是合成的广谱杀菌剂，用于控制真菌病害。它可阻碍线粒体呼吸链复合体 II 中的琥珀酸脱氢酶的作用，进而抑制真菌目标物种内的孢子萌发、芽管和菌丝生长。
T26046	Razoxane	Topoisomerase	DNA Damage/DNA Repair
	Razoxane 是拓扑异构酶 II 的有效抑制剂，具有抗血管生成的作用，在肾细胞癌中具有研究价值。
T60194	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide	Histone Methyltransferase	Chromatin/Epigenetic
	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide 是一种强效的、选择性的Enhancer of Zeste Homolog 2 (EZH2)，对EZH2 WT 和EZH2-Y641F 的IC50分别为37.6nM 和79.1nM。
T8501	3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide	Influenza Virus	Microbiology/Virology
	3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide 具有抗埃博拉病毒的抗病毒活性靶向表面暴露的糖蛋白并抑制病毒进入宿主细胞。 Vero 细胞的体外研究表明，该化合物抑制病毒复制，EC50 为 0.38 μM。
T8747	Levofloxacin hydrochloride	DNA gyrase; Topoisomerase	DNA Damage/DNA Repair
	Levofloxacin hydrochloride 是一种广谱的第三代氟喹诺酮类抗生素，是氧氟沙星的光学活性 L-异构体，具有抗菌活性。左氧氟沙星通过细菌细胞壁扩散并通过抑制 DNA 促旋酶（细菌拓扑异构酶 II）起作用，这是一种 DNA 复制、RNA 转录和细菌 DNA 修复所需的酶。 DNA 促旋酶活性的抑制导致细菌细胞生长受阻。
T1177	Sulfaquinoxaline 磺胺喹恶啉,Avicocid,磺胺喹噁啉,Sulphaquinoxaline,Sulfabenzpyrazine	Others; Antibacterial; Antibiotic; Parasite	Microbiology/Virology; Others
	Sulfaquinoxaline (Sulfabenzpyrazine) 是一种兽用抗菌剂，对革兰氏阴性菌和革兰氏阳性菌均有活性。它能用于预防球虫病和细菌感染。
T0644	3-Amino-5-methylisoxazole	Others	Others
	3-Amino-5-methylisoxazole 是医药中间体，用于生产磺胺类药物。
T36940	Spiroxamine	Others	Others
	Spiroxamine 是一种叔胺类杀菌剂，是 δ14 还原酶和 δ8→δ7 异构酶的抑制剂。 Spiroxamine 抑制从葡萄藤中分离出的 N. parvum、B. dothidea、D. seriata 和 L. theobromae 的生长。
T9835	4-QUinolinecarboxamide, N-[3-[[[2-[4-(aminosulfonyl)phenyl]ethyl]amino]carbonyl]phenyl]-1,2-dihydro-2-oxo-	Others	Others
	4-QUinolinecarboxamide, N-[3-[[[2-[4-(aminosulfonyl)phenyl]ethyl]amino]carbonyl]phenyl]-1,2-dihydro-2-oxo-是胺。
T67963	Teniloxazine
	Teniloxazine 是一种可口服的抗抑郁化合物，具有抗缺氧特性。
T7814	Alloxan monohydrate	Proteasome	Proteases/Proteasome; Ubiquitination
	Alloxan Monohydrate 是一种能够引起糖尿病的致糖尿病药物。它作为蛋白酶体抑制剂，破坏胰腺中能够分泌胰岛素的B 细胞，导致实验动物患糖尿病。
T20719	Oxadiargyl RP 020630,RP-020630,RP020630,丙炔恶草酮,Topstar	Others	Others
	Oxadiargyl (RP020630) 是原卟啉原氧化酶抑制剂，在我国被用作除草剂。
T60041	N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide	Microtubule Associated	Cytoskeletal Signaling
	N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide 是一种 TAU 细胞毒性抑制剂，抑制 M17-TAU P301L 细胞的 LDH 泄漏，EC50=325nM。
T32237	Isoxaben EL 107,NA 8318,Isoxaben； EL 107； NA 8318	Cell wall	Immunology/Inflammation
	Isoxaben (EL 107) 是一种细胞壁生物合成的特异性抑制剂，常作为除草剂使用，可抑制放射性标记的葡萄糖掺入酸不溶性细胞壁部分。
T6349L	Sitafloxacin DU6859,DU 6859,DU 6859A,Sitafloxacin anhydrous,DU-6859,DU6859A,DU-6859A,西他沙星
	Sitafloxacin, a new generation of broad-spectrum oral fluoroquinolones, is highly effective against many Gram-positive, Gram-negative, and anaerobic clinical isolates (including strains resistant to other fluoroquinolones).
T23283	2-Methoxyidazoxan monohydrochloride RX 821002 hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-Albizziin (2-Methoxyidazoxan monohydrochloride) 是高效的 alpha 2r 肾上腺素受体选择性拮抗剂，对 imidazoline 拮抗作用很小或没有。它对 (豚鼠) alpha 2D 肾上腺素受体 (pKd9.7) 的亲和力明显高于 (兔子) alpha 2A 肾上腺素受体 (pKd8.2)。
T13353	Xanomeline oxalate LY246708 oxalate	AChR	Neuroscience
	Xanomeline oxalate (LY246708 oxalate)作为一种高效且选择性的胆碱能受体激动剂(SMRA)，在体内有效促进磷脂酰肌醇水解。Xanomeline oxalate 对于阿尔茨海默病的研究具有重要价值。
T3117	Marbofloxacin 马波沙星,Marbofloxacine,Zeniquin,Marbocyl	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Marbofloxacin (Zeniquin) 是一种具有口服活性的氟喹诺酮类广谱抗菌剂。它可研究革兰氏阳性和革兰氏阴性细菌以及支原体引起的感染。
T1001	Dicloxacillin Sodium hydrate Dicloxacillin sodium salt monohydrate,双氯西林钠,Dicloxacillin sodium monohydrate	Antibacterial; Antibiotic	Microbiology/Virology
	Dicloxacillin Sodium hydrate 是一种青霉素类窄谱β内酰胺抗生素，可研究革兰氏阳性菌感染。
T124358	Deferoxamine Deferoxamine B,Desferrioxamine B	Apoptosis; Antioxidant; HIF; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; oxidation-reduction
	Deferoxamine（Desferrioxamine B）是一种铁螯合剂 (结合 Fe(III) 和许多其他金属阳离子)，可抑制神经元病变，可用于改减少铁在组织中的积累和沉积，可通过抑制创伤性脑损伤后的铁死亡和神经炎症来改善神经功能障碍。Desferrioxamin-B 具有抗氧化、抗增殖、抗肿瘤活性，可诱导 HIF-1α 产生，诱导癌细胞凋亡和自噬。Desferrioxamin-B 可用于治疗急性铁中毒和与 COVID-19 相关疾病。
T0993	Methoxamine hydrochloride Methoxamine HCl,盐酸甲氧明	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Methoxamine hydrochloride (Methoxamine HCl) 是一种 alpha1 肾上腺素能受体的选择性激动剂。它通过 Prazosin 敏感机制在兔肺动脉显著增加 ATP、ADP 和 AMP 的溢出，但不增加腺苷的溢出。它引起血管收缩和外周血管阻力增加。
T0985	Oxacillin sodium salt 苯唑西林,Oxacillin sodium,Oxabel	Antibacterial; Antibiotic	Microbiology/Virology
	Oxacillin sodium salt (Oxabel) 是一种青霉素类的窄谱β-内酰胺抗生素，用于耐药葡萄球菌感染。
T1031	Cloxacillin sodium monohydrate Cloxacillin Sodium,Bactopen,氯唑西林钠一水合物	Antibacterial; Antibiotic	Microbiology/Virology
	Cloxacillin sodium monohydrate (Cloxacillin Sodium) 有抗菌作用，对Staphylococcus aureus25923 的最小抑菌浓度为256 mg/L。
T0101	Doxazosin mesylate UK 33274 mesylate,甲磺酸多沙唑嗪	Mitophagy; Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Doxazosin mesylate (UK 33274 mesylate) 是一种喹唑啉衍生物。它是一种选择性拮抗突触后α1-肾上腺素能受体。
T1077	Fluvoxamine maleate 氟伏沙明马来酸盐,马来酸氟伏沙明,MK-264,DU-23000 (maleate)	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Fluvoxamine maleate (DU-23000 (maleate)) 是一种5-羟色胺再吸收抑制剂，有抗抑郁作用。

化合物

OXA (17-33) acetate

Cat.No: TP1973L

Target: OX Receptor

Cat.No: T28277

Synonym: OXA 11

Cat.No: TP1973

Synonym: OXA (17-33)

Cat.No: T21816

OXA-06 Dihydrochloride

Cat.No: T24574

OXA(17-33) TFA

Cat.No: T75922

Cat.No: T60050

Target: Antibacterial

Cat.No: T74688

mTOR inhibitor 13

Cat.No: T9310

Target: PI3K, mTOR

2-Oxa-1,4-butanediol diacetate

Cat.No: T66929

Ethyl (1S,5R,6S)-5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cat.No: T66969

1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea

Cat.No: T67700

(6S,9S,12S)-Benzyl 12-benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate

Cat.No: T66648

Cat.No: T9319

Synonym: tosufloxacin tosilate,托氟沙星,Ozex,7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Target: Others

(4S,5R)-3-tert-butoxycarbony-2-(4-anisy)-4-phenyl-5-oxazolidinecarboxylic acid

Cat.No: T64325

Target: Others

Naloxegol oxalate

Cat.No: T3355

Synonym: NKTR-118,NKTR-118 oxalate,AZ 13337019,AZ-13337019 oxalate

Target: P450

Cat.No: T19805

Synonym: BRN-4190275,解草酮,BRN 4190275,BRN4190275

Target: Others

(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid

Cat.No: T77670

Target: Somatostatin

Cat.No: T1293

Synonym: BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155,加替沙星

Target: Topoisomerase, Antibacterial, Antibiotic

MRS-3777 hemioxalate

Cat.No: T12107

Target: Adenosine Receptor

5-(2-furyl)-N-propylisoxazole-3-carboxamide

Cat.No: T50032

Target: Others

[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine

Cat.No: T50061

Target: Others

Cat.No: T7865

Synonym: 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine

Target: Others, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T20721

Synonym: RP 201772,异恶唑草酮,Merlin,RP-201772,RP201772

Target: Others

Cat.No: T22234

Target: Adenosine Receptor

Cat.No: T21136

Target: Antifungal

Cat.No: T26046

Target: Topoisomerase

N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide

Cat.No: T60194

Target: Histone Methyltransferase

3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide

Cat.No: T8501

Target: Influenza Virus

Levofloxacin hydrochloride

Cat.No: T8747

Target: DNA gyrase, Topoisomerase

Sulfaquinoxaline

Cat.No: T1177

Synonym: 磺胺喹恶啉,Avicocid,磺胺喹噁啉,Sulphaquinoxaline,Sulfabenzpyrazine

Target: Others, Antibacterial, Antibiotic, Parasite

3-Amino-5-methylisoxazole

Cat.No: T0644

Target: Others

Cat.No: T36940

Target: Others

4-QUinolinecarboxamide, N-[3-[[[2-[4-(aminosulfonyl)phenyl]ethyl]amino]carbonyl]phenyl]-1,2-dihydro-2-oxo-

Cat.No: T9835

Target: Others

Cat.No: T67963

Alloxan monohydrate

Cat.No: T7814

Target: Proteasome

Cat.No: T20719

Synonym: RP 020630,RP-020630,RP020630,丙炔恶草酮,Topstar

Target: Others

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide

Cat.No: T60041

Target: Microtubule Associated

Cat.No: T32237

Synonym: EL 107,NA 8318,Isoxaben； EL 107； NA 8318

Target: Cell wall

Cat.No: T6349L

Synonym: DU6859,DU 6859,DU 6859A,Sitafloxacin anhydrous,DU-6859,DU6859A,DU-6859A,西他沙星

2-Methoxyidazoxan monohydrochloride

Cat.No: T23283

Synonym: RX 821002 hydrochloride

Target: Adrenergic Receptor

Xanomeline oxalate

Cat.No: T13353

Synonym: LY246708 oxalate

Target: AChR

Cat.No: T3117

Synonym: 马波沙星,Marbofloxacine,Zeniquin,Marbocyl

Target: Topoisomerase, Antibacterial, Antibiotic

Dicloxacillin Sodium hydrate

Cat.No: T1001

Synonym: Dicloxacillin sodium salt monohydrate,双氯西林钠,Dicloxacillin sodium monohydrate

Target: Antibacterial, Antibiotic

Cat.No: T124358

Synonym: Deferoxamine B,Desferrioxamine B

Target: Apoptosis, Antioxidant, HIF, Autophagy

Methoxamine hydrochloride

Cat.No: T0993

Synonym: Methoxamine HCl,盐酸甲氧明

Target: Adrenergic Receptor

Oxacillin sodium salt

Cat.No: T0985

Synonym: 苯唑西林,Oxacillin sodium,Oxabel

Target: Antibacterial, Antibiotic

Cloxacillin sodium monohydrate

Cat.No: T1031

Synonym: Cloxacillin Sodium,Bactopen,氯唑西林钠一水合物

Target: Antibacterial, Antibiotic

Doxazosin mesylate

Cat.No: T0101

Synonym: UK 33274 mesylate,甲磺酸多沙唑嗪

Target: Mitophagy, Adrenergic Receptor, Autophagy

Fluvoxamine maleate

Cat.No: T1077

Synonym: 氟伏沙明马来酸盐,马来酸氟伏沙明,MK-264,DU-23000 (maleate)

Target: 5-HT Receptor, Serotonin Transporter

Cat. No.	Product Name	Target	Signaling Pathways
T5085	Pyridoxal 5'-phosphate hydrate Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),5-磷酸吡多醛水合物,PLP,Pyridoxal 5'-phosphate hydrate	Others; Endogenous Metabolite	Metabolism; Others
	Pyridoxal 5'-phosphate hydrate (PLP) 是内源性代谢产物的一种。
T5572	2-Benzoxazolinone 2-Benzoxazolone,1,3-Benzoxazol-2(3H)-one,2-Hydroxybenzoxazole,2-苯并唑啉酮	Parasite	Microbiology/Virology
	2-Benzoxazolinone (2-Hydroxybenzoxazole) 存在于黑麦幼苗中，是一种抗利什曼原虫试剂，抗 L. donovani 的 LC50为40 μg/mL。它的衍生物具有抗微生物活性，可针对一系列的革兰氏阳性和阴性细菌。
T6567	Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素，有抑制细菌DNA 旋转酶的超螺旋活性的作用，能阻止DNA 复制。
T5029	Oxaceprol 奥沙西罗,N-Acetyl-L-hydroxyproline,N-乙酰-L-4-羟基脯氨酸	Others	Others
	Oxaceprol (N-Acetyl-L-hydroxyproline) 是一种可口服的、具有显著抗炎作用的 L-脯氨酸衍生物，常用于研究骨关节炎和类风湿性关节炎。
T1276	Danofloxacin mesylate 甲磺酸达氟沙星,CP 76136-27	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Danofloxacin mesylate (CP 76136-27) 是一种兽医用氟喹诺酮类抗菌素。
T75643	Isoxanthohumol	HSV	Microbiology/Virology
	Isoxanthohumol 是一种从啤酒花和啤酒中提取的一种前黄酮类化合物，对几种人类癌细胞株具有抗增殖活性。Isoxanthohumol对肿瘤细胞肺转移灶的转移或侵袭有抑制作用。Isoxanthohumol具有抗病毒活性，对疱疹病毒（HSV1和HSV2）和牛病毒性腹泻病毒（BVDV）具有抑制作用。
T7957	2-Isopropyl Thioxanthone	Others	Others
	2-Isopropyl Thioxanthone 具有潜在的抗雌激素和抗雄激素特性。
T8130	Ciprofloxacin hydrochloride monohydrate Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan	Antibacterial; Antibiotic	Microbiology/Virology
	Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) 是一种具有高效抗菌活性的氟喹诺酮类抗生素。
T4914	Mesoxalate sodium (monohydrate) Sodium mesoxalate monohydrate,丙酮二酸钠	Others; Endogenous Metabolite	Metabolism; Others
	Mesoxalate sodium (monohydrate) 是内源性代谢产物的一种。
T4768	Diethyl oxalpropionate 草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE	Others; Endogenous Metabolite	Metabolism; Others
	Diethyl oxalpropionate (HYL 2-METHYL-3-OXOSUCCINATE) 是一种合成 PDMMLA 的中间体。其中 PDMMLA 的衍生物可用于纳米粒子的合成和研究。
T19154	5-Methyl-2-thiophenecarboxaldehyde	Others	Others
	5-Methyl-2-thiophenecarboxaldehyde 是一种候选的微观三阶非线性光学（NLO）材料。5-Methyl-2-thiophenecarboxaldehyde 具有广泛的生物活性，如抗癌活性。
T7600	Fucoxanthin all-trans-Fucoxanthin	Others	Others
	Fucoxanthin (all-trans-Fucoxanthin) 是海洋类胡萝卜素，具有抗肥胖，抗糖尿病，抗炎，抗氧化，抗癌等作用。
T4748	1,4-Dioxane-2,5-diol Glycolaldehyde dimer,乙醇醛二聚体,Hydroxyacetaldehyde dimer,2,5-Dihydroxy-1,4-dioxane	Others; Endogenous Metabolite	Metabolism; Others
	1,4-Dioxane-2,5-diol (Glycolaldehyde dimer) 是内源性代谢产物的一种。
T8105	Indole-3-carboxaldehyde 3-Formylindole,3-吲哚甲醛	Endogenous Metabolite	Metabolism
	Indole-3-carboxaldehyde (3-Formylindole) 是由黄化豌豆幼苗的粗酶制剂氧化降解IAA 的产物，是一种卷心菜提取物。它可用于制备吲哚类植物抗毒素环芸香素类似物。
T8083	Pyridoxal 5'-phosphate monohydrate Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛	Others	Others
	Pyridoxal 5'-phosphate monohydrate 是维生素 B6的活性形式，也是多种酶的重要辅因子。它是维生素 B6 在细胞内磷酸化过程中重要的辅酶变异体，能够与其他变异体（如 PNP 、 PMP）发生互换。
T19808	5-Bromo-5-nitro-1,3-dioxane Bronidox,5-溴-5-硝基-1,3-二噁烷,5-溴-5-硝基-1,3-二恶烷	Others; Antibacterial; Antifungal	Microbiology/Virology; Others
	5-Bromo-5-nitro-1,3-dioxane (Bronidox) 是一种抗菌化合物，可通过必需蛋白硫醇的氧化抑制酶活性并随后抑制微生物的生长。它有抗革兰氏阳性和革兰氏阴性细菌，以及抗真菌活性。
T8384	Gatifloxacin hydrochloride AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride),加替沙星盐酸盐	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Gatifloxacin hydrochloride (AM-1155 hydrochloride) 是一种氟喹诺酮类抗生素，有广谱抗菌活性。它可抑制大肠杆菌 DNA 解旋酶 (IC50=0.109 μg/ml)和细菌 II 型拓扑异构酶(IC50=13.8 μg/ml) 。它在动物模型中，可研究细菌性结膜炎。
T1705	5-Amino-3H-imidazole-4-Carboxamide 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide	Endogenous Metabolite	Metabolism
	5-Amino-3H-imidazole-4-Carboxamide (AICA) 是一种合成嘌呤（尤其是核碱基腺嘌呤和鸟嘌呤）的重要前体。
T0073	Octinoxate 2-Ethylhexyl 4-methoxycinnamate,ethylhexyl methoxycinnamate,Octyl 4-methoxycinnamate,甲氧基肉桂酸辛酯,Octyl methoxycinnamate,对甲氧基肉桂酸辛酯	Others	Others
	Octinoxate (Octyl 4-methoxycinnamate) 能够吸收来自太阳的 UV-B 射线，保护皮肤免受损伤，也可用于减少疤痕的外观，常用于是防晒霜和唇膏等化妆品中。
T3578	Pyridoxal phosphate PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate	Reverse Transcriptase; Endogenous Metabolite	Metabolism; Microbiology/Virology
	Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式，可抑制逆转录酶活性，用于研究迟发性运动障碍症。
T1362	Hypoxanthine 次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin	Others; Endogenous Metabolite	Metabolism; Others
	Hypoxanthine (Purin-6-ol)，也被称为 purine-6-ol 或 Hyp，是一种天然存在的嘌呤衍生物，是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下，Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤，黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。
TN7142	N-methyl-1H-indole-2-carboxamide 1H-indole-2-carboxylic acid methylamide,ZINC35137534,N-甲基-1H-吲哚-2-酰胺	Others	Others
	N-methyl-1H-indole-2-carboxamide (ZINC35137534) 是一种海洋来源的天然产物，存在于 Neosartorya pseudofischeri。
T4862	Oxaloacetic acid	Endogenous Metabolite	Metabolism
	Oxaloacetic acid 是一种代谢中间体，涉及多种途径，如葡萄糖异生、柠檬酸循环、乙醛酸循环、尿素循环、氨基酸合成和脂肪酸合成。
T7977	Benzofuroxan	Others	Others
	Benzofuroxan 被用作合成其他化合物的起始材料，如药物和其他化学品；也用于聚合物的合成；还被用于合成荧光染料，并作为检测某些分子的荧光探针。
T2O2680	Oxalic acid 草酸；修酸;无水草酸,Wood bleach,Aktisal,Aquisal,Ethanedioic acid	Others; Endogenous Metabolite	Metabolism; Others
	Oxalic acid (Ethanedioic acid) 是存在于许多植物和蔬菜中的强酸，作为分析试剂、一般还原剂。
T5064	Oxalic acid dihydrate 草酸二水合物,Ethanedioic acid dihydrate	Others; Endogenous Metabolite	Metabolism; Others
	Oxalic acid dihydrate (Ethanedioic acid dihydrate) 是内源性代谢产物的一种。
T1306	Norfloxacin 氟哌酸,MK-0366,诺氟沙星	DNA gyrase; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Norfloxacin (MK-0366) 是广谱抗生素，能通过结合DNA 旋转酶抑制革兰氏阳性和阴性菌。
T4S0999	(2S)-Isoxanthohumol Isoxanthohumol,(2S)-异黄腐酚,异黄腐醇	Virus Protease; HSV	Microbiology/Virology
	(2S)-Isoxanthohumol 是一种由啤酒花原异戊烯基二氢黄酮 Isoxanthohumol 的微生物转化代谢物。
T4761	Pyridoxal hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Pyridoxal hydrochloride 是内源性代谢产物的一种。
T8046	Tosufloxacin tosylate hydrate Tosufloxacin p-Toluenesulfonate Hydrate,A-61827 tosylate hydrate,对甲苯磺酸妥舒沙星水合物,T-3262 Tosylate Hydrate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Tosufloxacin tosylate hydrate (A-61827 tosylate hydrate) 是一个氟喹诺酮类抗菌剂。
TN3801	methoxyphenoxy]oxane-3,4,5-triol Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside	Others	Others
	Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside is a natural product from Ligusticopsis wallichiana (DC) Pimenov & Kljuykov.
T21290	1,3-Dioxane, 2,4-dimethyl-
	1,3-Dioxane, 2,4-dimethyl- is a bioactive chemical.
T10524	β-Cryptoxanthin (3R)-β-Cryptoxanthin	Others	Others
	β-Cryptoxanthin is isolated from Satsuma mandarin orange with an anti-stress effect. It is an oxygenated carotenoid and an antioxidant.
TN2744	2,7-Dihydroxy-2H-1,4-benzoxazin-3(4H)-one	Others	Others
	2,7-Dihydroxy-2H-1,4-benzoxazin-3(4H)-one是一种天然产物，属于玄参科野甘草属，其产品编号为 TN2744，CAS号为 69804-59-7。2,7-Dihydroxy-2H-1,4-benzoxazin-3(4H)-one可用作对照参考。
T21291	1,3-Dioxane, 4-methyl-
	1,3-Dioxane, 4-methyl- is a bioactive chemical.
T16356	Glyoxalic acid Oxalaldehydic acid,NSC 27785,Formylformic acid	Others	Others
	Glyoxalic acid is an organic compound. It is both an aldehyde and a carboxylic acid.
T70891	Pyridoxatin
	Pyridoxatin is a fungal metabolite that inhibits production of thiobarbituric acid reactive substance (TBARS). Pyridoxatin inhibits hemolysis induced by the free radical generator AAPH and is active against C. albicans.
TN6914	Neoxanthin
	Neoxanthin is a natural product.
TN6929	2-(3,4-Dihydroxyphenyl)-1,3-benzodioxole-5-carboxaldehyde
	2-(3,4-Dihydroxyphenyl)-1,3-benzodioxole-5-carboxaldehyde is a natural product.
T33641	Neoxaline Nedoxaline
	Neoxaline is an alkaloid isolated from fermentation broth of Aspergillus japonicus.
T10010	1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol	Others	Others
	1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is an endogenous metabolite.
T72731	Acremoxanthone C
	Acremoxantone C 是一种有效的钙调素(CaM)抑制剂，存在于 Purpureocillium lilacinum 中。Acremoxantone C 与人钙调素 (hCaM) 生物传感器 hCaM M124C mBBr 结合，Kd 为 18.25 nM。
T38264	2-Thiophenecarboxaldehyde
	2-Thiophenecarboxaldehyde is an endogenous metabolite.
TN6047	2-(1H-Indole-3-carboxamido)benzoic acid 板蓝根
	2-(1H-Indole-3-carboxamido)benzoic acid 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6047，CAS号为 171817-95-1。
T38395	Pyrrole-2-carboxaldehyde
	Pyrrole-2-carboxaldehyde exhibits distinctive vibrational and electronic properties which serve to validate its dimeric state in the solid phase and monomeric state in the solution phase.
T21098	Decamethylcyclopentasiloxane Dekamethylcyklopentasiloxan,Cyclopentasiloxane, decamethyl-
	Decamethylcyclopentasiloxane is a cyclic methylsiloxane with volatile properties.
TN4071	Formoxanthone A	Antifection	Microbiology/Virology
	Formoxanthone A 可能具有抗菌和细胞毒性活性。
T24412	Lipoxamycin G 26146,G-26146,G26146,Neoenactin M1
	Lipoxamycin is an inhibitor of serine palmitoyl-transferase.
TN6641	3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal
	3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6641，CAS号为 60026-28-0。
TN5915	Caloxanthone B
	Caloxanthone B 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5915，CAS号为 155233-17-3。
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天然产物

Pyridoxal 5'-phosphate hydrate

Cat.No: T5085

Synonym: Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),5-磷酸吡多醛水合物,PLP,Pyridoxal 5'-phosphate hydrate

Target: Others, Endogenous Metabolite

2-Benzoxazolinone

Cat.No: T5572

Synonym: 2-Benzoxazolone,1,3-Benzoxazol-2(3H)-one,2-Hydroxybenzoxazole,2-苯并唑啉酮

Target: Parasite

Cat.No: T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T5029

Synonym: 奥沙西罗,N-Acetyl-L-hydroxyproline,N-乙酰-L-4-羟基脯氨酸

Target: Others

Danofloxacin mesylate

Cat.No: T1276

Synonym: 甲磺酸达氟沙星,CP 76136-27

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T75643

Target: HSV

2-Isopropyl Thioxanthone

Cat.No: T7957

Target: Others

Ciprofloxacin hydrochloride monohydrate

Cat.No: T8130

Synonym: Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan

Target: Antibacterial, Antibiotic

Mesoxalate sodium (monohydrate)

Cat.No: T4914

Synonym: Sodium mesoxalate monohydrate,丙酮二酸钠

Target: Others, Endogenous Metabolite

Diethyl oxalpropionate

Cat.No: T4768

Synonym: 草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE

Target: Others, Endogenous Metabolite

5-Methyl-2-thiophenecarboxaldehyde

Cat.No: T19154

Target: Others

Cat.No: T7600

Synonym: all-trans-Fucoxanthin

Target: Others

1,4-Dioxane-2,5-diol

Cat.No: T4748

Synonym: Glycolaldehyde dimer,乙醇醛二聚体,Hydroxyacetaldehyde dimer,2,5-Dihydroxy-1,4-dioxane

Target: Others, Endogenous Metabolite

Indole-3-carboxaldehyde

Cat.No: T8105

Synonym: 3-Formylindole,3-吲哚甲醛

Target: Endogenous Metabolite

Pyridoxal 5'-phosphate monohydrate

Cat.No: T8083

Synonym: Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛

Target: Others

5-Bromo-5-nitro-1,3-dioxane

Cat.No: T19808

Synonym: Bronidox,5-溴-5-硝基-1,3-二噁烷,5-溴-5-硝基-1,3-二恶烷

Target: Others, Antibacterial, Antifungal

Gatifloxacin hydrochloride

Cat.No: T8384

Synonym: AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride),加替沙星盐酸盐

Target: Topoisomerase, Antibacterial, Antibiotic

5-Amino-3H-imidazole-4-Carboxamide

Cat.No: T1705

Synonym: 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide

Target: Endogenous Metabolite

Cat.No: T0073

Synonym: 2-Ethylhexyl 4-methoxycinnamate,ethylhexyl methoxycinnamate,Octyl 4-methoxycinnamate,甲氧基肉桂酸辛酯,Octyl methoxycinnamate,对甲氧基肉桂酸辛酯

Target: Others

Pyridoxal phosphate

Cat.No: T3578

Synonym: PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Target: Reverse Transcriptase, Endogenous Metabolite

Cat.No: T1362

Synonym: 次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin

Target: Others, Endogenous Metabolite

N-methyl-1H-indole-2-carboxamide

Cat.No: TN7142

Synonym: 1H-indole-2-carboxylic acid methylamide,ZINC35137534,N-甲基-1H-吲哚-2-酰胺

Target: Others

Oxaloacetic acid

Cat.No: T4862

Target: Endogenous Metabolite

Cat.No: T7977

Target: Others

Cat.No: T2O2680

Synonym: 草酸；修酸;无水草酸,Wood bleach,Aktisal,Aquisal,Ethanedioic acid

Target: Others, Endogenous Metabolite

Oxalic acid dihydrate

Cat.No: T5064

Synonym: 草酸二水合物,Ethanedioic acid dihydrate

Target: Others, Endogenous Metabolite

Cat.No: T1306

Synonym: 氟哌酸,MK-0366,诺氟沙星

Target: DNA gyrase, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic

(2S)-Isoxanthohumol

Cat.No: T4S0999

Synonym: Isoxanthohumol,(2S)-异黄腐酚,异黄腐醇

Target: Virus Protease, HSV

Pyridoxal hydrochloride

Cat.No: T4761

Target: Others, Endogenous Metabolite

Tosufloxacin tosylate hydrate

Cat.No: T8046

Synonym: Tosufloxacin p-Toluenesulfonate Hydrate,A-61827 tosylate hydrate,对甲苯磺酸妥舒沙星水合物,T-3262 Tosylate Hydrate

Target: Others, Antibacterial, Antibiotic

methoxyphenoxy]oxane-3,4,5-triol

Cat.No: TN3801

Synonym: Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside

Target: Others

1,3-Dioxane, 2,4-dimethyl-

Cat.No: T21290

β-Cryptoxanthin

Cat.No: T10524

Synonym: (3R)-β-Cryptoxanthin

Target: Others

2,7-Dihydroxy-2H-1,4-benzoxazin-3(4H)-one

Cat.No: TN2744

Target: Others

1,3-Dioxane, 4-methyl-

Cat.No: T21291

Cat.No: T16356

Synonym: Oxalaldehydic acid,NSC 27785,Formylformic acid

Target: Others

Cat.No: T70891

Cat.No: TN6914

2-(3,4-Dihydroxyphenyl)-1,3-benzodioxole-5-carboxaldehyde

Cat.No: TN6929

Cat.No: T33641

Synonym: Nedoxaline

1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol

Cat.No: T10010

Target: Others

Acremoxanthone C

Cat.No: T72731

2-Thiophenecarboxaldehyde

Cat.No: T38264

2-(1H-Indole-3-carboxamido)benzoic acid

Cat.No: TN6047

Synonym: 板蓝根

Pyrrole-2-carboxaldehyde

Cat.No: T38395

Decamethylcyclopentasiloxane

Cat.No: T21098

Synonym: Dekamethylcyklopentasiloxan,Cyclopentasiloxane, decamethyl-

Formoxanthone A

Cat.No: TN4071

Target: Antifection

Cat.No: T24412

Synonym: G 26146,G-26146,G26146,Neoenactin M1

3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal

Cat.No: TN6641

Cat.No: TN5915

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