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Targets Recommended: Raf Ras

18

抑制剂 & 化合物

8

天然产物

1749

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T24437 MCP110

MCP-110,MCP 110

Raf; Ras GPCR/G Protein; MAPK
MCP110 是 Ras 与 Raf-1 相互作用的抑制剂,可用于治疗人类肿瘤的研究。
T13114 CCR2 antagonist 4

Teijin compound 1

CCR Immunology/Inflammation; Microbiology/Virology
CCR2 antagonist 4 (Teijin compound 1) 是高效的、特异性的CCR2拮抗剂,对 CCR2b 的IC50为 180 nM,抑制 MCP-1 诱导的趋化作用的 IC50为 24 nM。
T8316 1V209

TLR7 agonist T7

TLR Immunology/Inflammation
1V209 (TLR7 agonist T7) 是一种 Toll 样受体 7 (TLR7) 激动剂,可与各种多糖缀合,以改善其水溶性,增强功效并保持低毒性,具有抗肿瘤作用。
T11648 INCB 3284

Others Others
INCB 3284, a potent and selective human CCR2 antagonist with an oral bioavailability, is utilized in the study of acute liver failure. It effectively inhibits the binding of monocyte chemoattractant protein-1 (MCP-1) to hCCR2, demonstrating an IC50 of 3.7 nM.
T11079 NMI 8739

n-docosahexaenoyl dopamine,Dha-DA conjugate

Dopamine Receptor GPCR/G Protein; Neuroscience
NMI 8739 (n-docosahexaenoyl dopamine) 是 D2 自身受体的激动剂。 NMI 8739 减少 NO 的产生并引起 CCL-20、MCP-1 和 IL-6 释放的浓度依赖性抑制。
T16091 MK-0812 Succinate

Others; CCR Immunology/Inflammation; Microbiology/Virology; Others
MK-0812 Succinate 是一种选择性CCR2拮抗剂。
T78806 PPARδ agonist 9

PPAR DNA Damage/DNA Repair; Metabolism
PPARδ agonist9 (compound 21) 作为PPARδ激动剂,展现出EC50为3.6 nM的活性。在体内实验中,PPARδ agonist9能有效降低小鼠血清中MCP-1水平,并在LDLr-KO模型中显著抑制动脉粥样硬化的发展,其抑制率达50-60%。
T19230 CCR2 antagonist 4 hydrochloride

Teijin compound 1 hydrochloride

Others Others
CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).
T80059 Complement factor I

Endogenous Metabolite Metabolism
Complement factor I,一丝氨酸蛋白酶,可与辅助因子H (FH)、补体受体1 (CR1/CD35)、C4结合蛋白 (C4BP) 或膜辅助因子蛋白 (MCP/CD46) 结合,调控液相及/或细胞表面补体系统的活性。
T36198 Avenanthramide-C methyl ester

Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.
T68721 Cantharidin imide

Cantharidin imide is a PP1/2A inhibitor found in Canarthis vesicatoria. It inhibits proliferation of colorectal cancer cells, increases MCP-1, IL-6, and IL-β levels, and inhibits differentiation and resorptive activity of osteoclasts. This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
T36130 22(S)-hydroxy Cholesterol

22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol

22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatocytes and downregulates mRNA expression of the LXR target genes CD36, ACSL1, and SCD-1 in human myotubes. It decreases triacylglycerol and diacylglycerol synthesis from labeled palmitate and acetate, respectively, in human myoblasts by 50% when used at a concentration of 10 uM. 22...
T82233 HCAR2 agonist 1

HCAR2 agonist 1 (Compound 9n) 是一种偏向Gi蛋白的变构调节剂,能够激活Gi蛋白相关的信号传导通路。该化合物展现了明显的抗炎效果,能够显著降低促炎细胞因子(TNF-α、IL-1β、IL-6 和 MCP-1)的mRNA表达水平,并在结肠炎小鼠模型中增强正位激动剂的抗炎作用。
T71884 ß-Carboline-1-carboxylic acid

β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 µg/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells. β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 µg/ml, respectively) but not Hep...
T7499 TAK-779

Takeda 779

HIV Protease; CXCR; CCR Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
TAK-779 (Takeda 779) 是一种非肽类CCR5和CXCR3 拮抗剂,对CCR5的Ki 值为 1.1 nM,并选择性抑制R5 HIV-1
T11647 INCB 3284 dimesylate

Others Others
INCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM). It can be used in the research of acute liver failure.
T37861 Talabostat

Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 and some other DASH family enzymes essentially as potently as it inhibits DPP-IV[1]. Talabostat stimulates the immune system by triggering a proinflammatory form of cell death in monocytes and macrophages known as pyroptosis. The inhibition of two serine proteases, DPP8 and DPP9,...
T14845 BX471 hydrochloride

ZK-811752 hydrochloride

Others Others
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.

化合物

MCP110
Cat.No: T24437
Synonym: MCP-110,MCP 110
Target: Raf, Ras
CCR2 antagonist 4
Cat.No: T13114
Synonym: Teijin compound 1
Target: CCR
1V209
Cat.No: T8316
Synonym: TLR7 agonist T7
Target: TLR
INCB 3284
Cat.No: T11648
Synonym:
Target: Others
NMI 8739
Cat.No: T11079
Synonym: n-docosahexaenoyl dopamine,Dha-DA conjugate
Target: Dopamine Receptor
MK-0812 Succinate
Cat.No: T16091
Synonym:
Target: Others, CCR
PPARδ agonist 9
Cat.No: T78806
Synonym:
Target: PPAR
CCR2 antagonist 4 hydrochloride
Cat.No: T19230
Synonym: Teijin compound 1 hydrochloride
Target: Others
Complement factor I
Cat.No: T80059
Synonym:
Target: Endogenous Metabolite
Avenanthramide-C methyl ester
Cat.No: T36198
Synonym:
Target:
Cantharidin imide
Cat.No: T68721
Synonym:
Target:
22(S)-hydroxy Cholesterol
Cat.No: T36130
Synonym: 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol
Target:
HCAR2 agonist 1
Cat.No: T82233
Synonym:
Target:
ß-Carboline-1-carboxylic acid
Cat.No: T71884
Synonym:
Target:
TAK-779
Cat.No: T7499
Synonym: Takeda 779
Target: HIV Protease, CXCR, CCR
INCB 3284 dimesylate
Cat.No: T11647
Synonym:
Target: Others
Talabostat
Cat.No: T37861
Synonym:
Target:
BX471 hydrochloride
Cat.No: T14845
Synonym: ZK-811752 hydrochloride
Target: Others
Cat. No. Product Name Target Signaling Pathways
T6413 Bindarit

宾达利,AF2838

CCR Immunology/Inflammation; Microbiology/Virology
Bindarit (AF2838) 是单核细胞趋化蛋白MCP-1/CCL2,MCP-3/CCL7和MCP-2/CCL8的选择性抑制剂,具有抗炎作用。
TC0036 Compound Lup-20(29)-en-3-yl acetate

IL Receptor; VEGFR; Others; TNF; COX Angiogenesis; Apoptosis; Immunology/Inflammation; Neuroscience; Others; Tyrosine Kinase/Adaptors
Lup-20(29)-en-3-yl acetate 是 Lupeol 的衍生物,通过下调 TNF-α、IL-1β、MCP-1、COX-2、VEGF 和颗粒酶 B 来抑制类风湿性关节炎的进展。
T4S0795 Berberrubine chloride

9-Berberoline Chloride,Beroline,Beroline Chloride,小檗红碱,Berberrubine,9-Berberoline

IL Receptor Immunology/Inflammation
Berberrubine chloride (9-Berberoline Chloride) 是一种黄连素的有效代谢物,能够改善动物模型中溃疡性结肠炎的症状。
T5688 Micheliolide

NOS; NF-κB; COX Immunology/Inflammation; Neuroscience; NF-κB
Micheliolide 是一种倍半萜内酯,能够抑制各种炎症反应。它能减弱高糖刺激的NF-κB 活化,IκBα的降解,和MCP-1,TGF-β1,FN 在鼠系膜细胞的表达。
TN1154 Nepetin

6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素

Calcium Channel; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮,具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。
T4S0350 Licochalcone B

甘草查尔酮 B,甘草查尔酮B

Beta Amyloid; Others Neuroscience; Others
Licochalcone B 是从Glycyrrhiza inflate 根中提取的。它能够抑制淀粉样蛋白 β 自聚集作用 (IC50=2.16 μM) ,分解预先形成的 Aβ42原纤维,并通过螯合金属离子抑制金属诱导的 Aβ42聚集。
TN5593 Euphohelioscopin A

Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity
T38285 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

Others Others
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))是成熟髓鞘中主要的硫酸盐类化合物。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) 在大鼠小脑中发现活跃的髓发生鞘化反应时积累率高于C24 3'-sulfo 半乳糖甘油酰胺。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))与C 型凝集素和免疫球蛋白样受体相互作用使对LMIR5的亲和力高。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))诱导嗜碱细胞产生MCP-1,可通过增加LMIR5激活NFAT,但不能诱导肥大细胞 。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))在体外与CD1d 结合,并增加游离小鼠脾细胞的增殖。

天然产物

Bindarit
Cat.No: T6413
Synonym: 宾达利,AF2838
Target: CCR
Compound Lup-20(29)-en-3-yl acetate
Cat.No: TC0036
Synonym:
Target: IL Receptor, VEGFR, Others, TNF, COX
Berberrubine chloride
Cat.No: T4S0795
Synonym: 9-Berberoline Chloride,Beroline,Beroline Chloride,小檗红碱,Berberrubine,9-Berberoline
Target: IL Receptor
Micheliolide
Cat.No: T5688
Synonym:
Target: NOS, NF-κB, COX
Nepetin
Cat.No: TN1154
Synonym: 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素
Target: Calcium Channel, Histamine Receptor
Licochalcone B
Cat.No: T4S0350
Synonym: 甘草查尔酮 B,甘草查尔酮B
Target: Beta Amyloid, Others
Euphohelioscopin A
Cat.No: TN5593
Synonym:
Target:
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
Cat.No: T38285
Synonym: C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
Target: Others
Cat. No. Product Name Species Expression System
TMPY-00118 MCP-1/CCL2 Protein, Human, Recombinant (His)

SCYA2,HC11,MCAF,HSMCR30,MCP-1...

Human P. pastoris (Yeast)
MCP-1/CCL2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P13500.
TMPY-00606 MCP-1/CCL2 Protein, Mouse, Recombinant (His)

AI323594,HC11,Sigje,MCP-1

Mouse Baculovirus Insect Cells
MCP-1/CCL2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148.
TMPY-05653 MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated

MCP-1,chemokine (C-C motif) ligand 2,HC

Mouse Baculovirus Insect Cells
MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148.
TMPK-00916 MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)

MCP-1,MCP1,SCYA2,GDCF-2,...

Cynomolgus HEK293 Cells
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 9.79 kDa and the accession number is P61274.
TMPK-00010 MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)

MCP-1,MCAF,GDCF-2,SMC-CF,C-C motif chemoki...

Human HEK293 Cells
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the accession number is P13500.
TMPK-00011 MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated

SMC-CF,HC11,MCAF,MCP1,

Human HEK293 Cells
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the accession number is P13500.
TMPY-01027 Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)

carnitine palmitoyltransferase 1B (muscle),AV080368...

Mouse HEK293 Cells
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. It is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. The granule-derived mouse mast cell proteases-1 and -2 (mMCP-1 and -2) colocalize in similar quantities in mucosal mast cells but micrograms of mMCP-1 compared w...
TMPJ-00852 CCL2 Protein, Rat, Recombinant (His)

C-C motif chemokine 2,Small-inducible cytokine A2,Monocyte c...

Rat HEK293 Cells
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils but not eosinophils or neutrophils. CCL2 binds the cognate receptor CCR2, and together this signaling pair has been shown to have multiple pro-tumorigenic roles, from mediating tumor growth and angiogenesis to recruiting and usurping host stromal cells to support tumor progression. CCL2 is found in the circulation, where it has ...
TMPY-00564 MCP-4 Protein, Human, Recombinant (His)

MCP-4,CCL13,SCYL1,NCC-1,...

Human P. pastoris (Yeast)
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chem...
TMPK-00879 CCR2b Protein-VLP, Human, Recombinant

C-C CKR-2,CCR2,MCP-1-R,CCR-2,CMKBR2

Human HEK293 Cells
The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane stru...
TMPJ-00028 CCL2 Protein, Mouse, Recombinant

Ccl2,Je,Mcp1,C-C motif chemokine 2,Platele...

Mouse E. coli
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equine, porcine, bovine and canine CCL2, respectively. Fibroblasts, glioma cells, smooth muscle cells, endothelial cells, lymphocytes and mononuclear phagocytes can produce CCL2 either constitutively or upon mitogenic stimulation, but monocytes and macrophages appear to be the major...
TMPJ-00009 CCL2 Protein, Human, Recombinant

C-C motif chemokine 2,MCAF,CCL2,MCP-1,Mono...

Human E. coli
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation...
TMPY-01887 MCP-2 Protein, Human, Recombinant (SUMO)

HC14,MCP-2,chemokine (C-C motif) ligand 8,...

Human E. coli
MCP-2 Protein, Human, Recombinant (SUMO) is expressed in E. coli expression system with SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P80075-1.
TMPY-04671 MCP-5 Protein, Mouse, Recombinant (His)

chemokine (C-C motif) ligand 12,MCP-5,Scya...

Mouse P. pastoris (Yeast)
Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impaired fibronectin and collagen deposition and indirectly stimulated collagen degradation through upregulation of matrix metalloproteinase-2. In post-MI patients, circulating LPS levels strongly associated with the Ccl12 homologue monocyte chemotactic protein 1 (MCP-1). Both MCP-1 ...
TMPY-02023 CD46 Protein, Human, Recombinant (His)

AHUS2,MIC10,CD46 molecule, complement regulatory pr...

Human HEK293 Cells
CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic...
TMPJ-00968 NAMPT Protein, Human, Recombinant (His)

PBEF,PBEF1,Nicotinamide phosphoribosyltransferase,N...

Human E. coli
Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine “visfatin”. PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular and extracellular forms. Most of the intracellular functions of PBEF are ...
TMPY-04411 YES1 Protein, Human, Recombinant (His & GST)

HsT441,c-yes,YES proto-oncogene 1, Src fam...

Human Baculovirus Insect Cells
Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 / c-Yes contains one protein kinase domain, one SH2 domain and one SH3 domain. It is thought that the subcellular distribution of Src-family tyrosine kinases, including c-Yes binding to the cellular membrane, is membranous and/or cytoplasmic. YES1 / c-Yes protein tyrosine kinase i...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi)

ACE2,ACE-2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00861 IL-33 Protein, Human, Recombinant

IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...

Human E. coli
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His)

FLK2,FLK-2,CD135,STK1,fms-related tyrosine...

Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His)

KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His)

thymic stromal lymphopoietin

Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

R-spondin 2,CRISTIN2

Human HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant

FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL

Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant

LAG-3,lymphocyte-activation gene 3,CD223

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular c...

Human HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-04165 FGFR3 Protein, Human, Recombinant (His)

JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His)

BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3

Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-01949 CD19 Protein, Human, Recombinant (His)

CD19 molecule,B4,CVID3

Human HEK293 Cells
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-05208 PD-L1 Protein, Human, Recombinant

CD274 molecule,PDCD1L1,PD-L1,PDL<...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-00853 IL-1RA Protein, Human, Recombinant

DIRA,IL1RA,interleukin 1 receptor antagoni...

Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01862 IL-4 Protein, Human, Recombinant

Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF

Human E. coli
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His)

leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C

Human HEK293 Cells
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-04333 LRRC15 Protein, Human, Recombinant (hFc)

leucine rich repeat containing 15,LIB

Human HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G1<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S)

Ighg1,IgG1 Fc

Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-04104 LIF Protein, Human, Recombinant

CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HILDA

Human HEK293 Cells
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-03290 HGF Protein, Mouse, Recombinant

hepatocyte growth factor (hepapoietin A,NK1,scatter...

Mouse HEK293 Cells
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-01894 SIGIRR Protein, Human, Recombinant (His)

TIR8,single immunoglobulin and toll-interleukin 1 r...

Human HEK293 Cells
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor receptor sup...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
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重组蛋白

MCP-1/CCL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00118
Species: Human
Expression System: P. pastoris (Yeast)
MCP-1/CCL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00606
Species: Mouse
Expression System: Baculovirus Insect Cells
MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05653
Species: Mouse
Expression System: Baculovirus Insect Cells
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00916
Species: Cynomolgus
Expression System: HEK293 Cells
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00010
Species: Human
Expression System: HEK293 Cells
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00011
Species: Human
Expression System: HEK293 Cells
Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01027
Species: Mouse
Expression System: HEK293 Cells
CCL2 Protein, Rat, Recombinant (His)
Cat.No: TMPJ-00852
Species: Rat
Expression System: HEK293 Cells
MCP-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-00564
Species: Human
Expression System: P. pastoris (Yeast)
CCR2b Protein-VLP, Human, Recombinant
Cat.No: TMPK-00879
Species: Human
Expression System: HEK293 Cells
CCL2 Protein, Mouse, Recombinant
Cat.No: TMPJ-00028
Species: Mouse
Expression System: E. coli
CCL2 Protein, Human, Recombinant
Cat.No: TMPJ-00009
Species: Human
Expression System: E. coli
MCP-2 Protein, Human, Recombinant (SUMO)
Cat.No: TMPY-01887
Species: Human
Expression System: E. coli
MCP-5 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04671
Species: Mouse
Expression System: P. pastoris (Yeast)
CD46 Protein, Human, Recombinant (His)
Cat.No: TMPY-02023
Species: Human
Expression System: HEK293 Cells
NAMPT Protein, Human, Recombinant (His)
Cat.No: TMPJ-00968
Species: Human
Expression System: E. coli
YES1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04411
Species: Human
Expression System: Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03745
Species: Human
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00383
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
IL-33 Protein, Human, Recombinant
Cat.No: TMPY-00861
Species: Human
Expression System: E. coli
FLT3 Protein, Human, Recombinant (T227M, His)
Cat.No: TMPY-01247
Species: Human
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01185
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
Cat.No: TMPY-05220
Species: Human
Expression System: HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06418
Species: Human
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant
Cat.No: TMPY-06873
Species: Human
Expression System: E. coli
LAG-3 Protein, Human, Recombinant
Cat.No: TMPY-04939
Species: Human
Expression System: HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04165
Species: Human
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03967
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (His)
Cat.No: TMPY-01949
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant
Cat.No: TMPY-05208
Species: Human
Expression System: HEK293 Cells
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
IL-1RA Protein, Human, Recombinant
Cat.No: TMPY-00853
Species: Human
Expression System: E. coli
IL-4 Protein, Human, Recombinant
Cat.No: TMPY-01862
Species: Human
Expression System: E. coli
LILRB5/CD85c Protein, Human, Recombinant (His)
Cat.No: TMPY-04826
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04333
Species: Human
Expression System: HEK293 Cells
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
Cat.No: TMPY-00820
Species: Human
Expression System: HEK293 Cells
LIF Protein, Human, Recombinant
Cat.No: TMPY-04104
Species: Human
Expression System: HEK293 Cells
HGF Protein, Mouse, Recombinant
Cat.No: TMPY-03290
Species: Mouse
Expression System: HEK293 Cells
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
SIGIRR Protein, Human, Recombinant (His)
Cat.No: TMPY-01894
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
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