41
2
102
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8874 |
FB23
|
Others | Others |
FB23 是FTO 去甲基化酶选择性抑制剂(IC50:60 nM)。它能够直接与FTO 结合,选择性的抑制FTO 的 mRNA N6-甲基腺嘌呤脱甲基酶活性。 | |||
T6139L |
A-674563 2HCl(552325-73-2(fb-2hcl))
|
ERK; Akt; PKA; CDK; PKC | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
A-674563 2HCl(552325-73-2(fb-2hcl)) 是一种 Akt1 抑制剂,Ki 为 11 nM,对 PKA 有效,对 Akt1 的选择性比 PKC 高 30 倍以上。 | |||
TP1736L |
Fibrinogen-Binding Peptide 137235-80-4(fb-acetate)
|
Others | Others |
Fibrinogen-Binding Peptide 137235-80-4(fb-acetate) 是纤维蛋白原受体上玻连蛋白结合位点的推定肽模拟物。它结合纤维蛋白原并抑制血小板与纤维蛋白原的粘附和血小板聚集,还抑制血小板与玻连蛋白的粘附 | |||
T0506 |
Clotrimazole
克霉唑,BAY b 5097,FB 5097 |
Antibacterial; Antibiotic; Antifection; Autophagy; Antifungal | Autophagy; Microbiology/Virology |
Clotrimazole (FB 5097) 是咪唑衍生物,有抗真菌和抗菌活性,是 P450抑制剂。 | |||
T7138 |
FB23-2
|
Apoptosis; Others | Apoptosis; Others |
FB23-2 是一种 mRNA N6- 甲基腺嘌呤脱甲基酶 FTO 选择性抑制剂,IC50值为 2.6 μM。它具有抗增殖作用,可研究急性髓系白血病。 | |||
TP1918L |
Lys-[Des-Arg9]Bradykinin,TFA
Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa) |
Bradykinin Receptor | GPCR/G Protein |
Lys-[Des-Arg9]Bradykinin,TFA (71800-36-7 free base) 是内源性强效和高选择性的缓激肽 B1 受体激动剂(对人 B1 和 B2 受体的 Ki 值分别为 0.12 和 > 30000 nM)。降低体内外周血管阻力的降压药。比 [Des-Arg9]-缓激肽强 16 倍。 | |||
T74683 | IONIS-FB-LRx | ||
IONIS-FB-LRx 是一种靶向补体因子 B (CFB) 的特殊反义寡核苷酸(ASO)。IONIS-FB-LRx 能有效降低 CFB 的循环水平。IONIS-FB-LRx 可用于地理萎缩 (GA) 研究。 | |||
T20231 |
Cellufluor
Phorwite AR,Paper White BP,Kayaphor FB,Tinopal 5BMS |
||
Cellufluor is a fluorochrome. It has an affinity for chitin and cellulose. | |||
T79770 |
FB49
|
Autophagy | Autophagy |
FB49是一种针对Bcl-2-associated athanogene 3 (BAG3)的高选择性抑制剂,具有Ki值为45 μM。在人类肿瘤细胞系中,FB49能够有效抑制细胞生长,同时对人外周单核细胞无明显毒性。此外,FB49能够在HD-MB03成神经管细胞瘤细胞中阻碍G1期的细胞周期进程,并诱导细胞凋亡(apoptosis)和自噬(autophagy)。 | |||
T77806 |
KRAS inhibitor FB9
|
||
KRAS inhibitor FB9 可用于 Ras 相关研究。 | |||
T11394 |
GFB-8438
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
GFB-8438 是有效的TRPC5选择性抑制剂,对 hTRPC5 和 hTRPC4 的IC50分别为 0.18 和 0.29 μM。它对 TRPC6、其他 TRP 家族成员、NaV1.5 具有良好的选择性,对 hERG 通道的活性也有限。它对小鼠足细胞的保护作用。 | |||
T11918L |
Lysipressin acetate(50-57-7(fb_acetate))
Lysine vasopressin acetate,[Lys8]-Vasopressin acetate |
Others | Others |
Lysipressin acetate(50-57-7(fb_acetate)) ([Lys8]-Vasopressin acetate) 诱导兔膀胱平滑肌收缩,激活腺苷酸环化酶。 Lysipressin 是一种抗利尿激素,已在猪和一些有袋动物家族中发现。 | |||
T111959 |
IFB-088 acetate
|
||
IFB-088 acetate 是一种苄基胍衍生物,可用于治疗与PPP1R15A 途径相关并与蛋白质错误折叠应激相关的疾病和癌症,如tau 病、突触核蛋白病、多谷氨酰胺和多丙氨酸疾病、白质营养不良、囊性纤维化、多发性硬化症、溶酶体储存障碍、淀粉样变性疾病、炎症、代谢障碍、心血管疾病、骨质疏松症、神经系统创伤等等。 | |||
T12338 |
OXFBD04
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
OXFBD04 是有效的、选择性的 BRD4 抑制剂(IC50= 166 nM)。OXFBD04 是有效的 BET 溴结构域配体,具有对 CREBBP 溴结构域额外的适度亲和力。OXFBD04 显示出抗癌活性。 | |||
T39518 |
PFB-FDGlu
|
Others | Others |
PFB-FDGlu 是一种溶酶体葡糖脑苷脂酶(GCase)底物,具有细胞渗透特异性,裂解后产生荧光素。PFB-FDGlu 通常与流式细胞仪结合使用,以单个细胞为基础测量活细胞中 GCase 的活性。 | |||
T8531 |
m-3M3FBS
2,4,6-三甲基-N-[3-(三氟甲基)苯基]苯磺酰胺 |
Apoptosis; Phospholipase | Apoptosis; Metabolism |
m-3M3FBS 是一种有效的磷脂酶C 激活剂,刺激人中性粒细胞产生超氧物,上调细胞内钙离子浓度,刺激多种细胞产生磷酸肌醇。它诱导单核细胞白血病细胞凋亡。 | |||
T14365 |
AZ PFKFB3 26
|
Glucokinase | Metabolism |
AZ PFKFB3 26 是一种有效的特异性 PFKFB3 抑制剂,IC50 为 23 nM。 PFKFB1 和 PFKFB2 的 IC50 分别为 2.06 和 0.384 μM。 | |||
T23101 |
o-3M3FBS
|
Others | Others |
o-3M3FBS 是 m-3M3FBS 的阴性对照。它以独立于 PLC 的机制及拮抗方式抑制内向和外向电流。它以与 m-3M3FBS 竞争的方式增加 [Ca2+]i 增加。 | |||
T67874 |
PFKFB3-IN-2
|
Glucokinase | Metabolism |
PFKFB3-IN-2是一种6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶3 (PFKFB3)抑制剂。在体内,对PFKFB3进行反义治疗可降低肿瘤生长速度。 | |||
T22081 |
FBPase-1 inhibitor-1
Fructose 1,6-bisphosphatase-1 Inhibitor |
Others | Others |
FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) 是一种fructose-1,6-bisphosphatase (FBPase-1)的变构抑制剂。 | |||
T19643 |
Cefbuperazone Sodium
T 1982,BMY25182,BMY 25182,T-1982,BMY-25182,T1982 |
||
Cefbuperazone Sodium is a penicillin-binding protein inhibitor. It is used as antibacterials. | |||
T62695 |
GFB-12811
|
||
GFB-12811,一种具有高选择性的口服活性CDK5抑制剂,其IC50为2.3 nM。该化合物对其他CDK激酶(CDK1/2/6/7/9)表现出显著的选择性。 | |||
T62894 | AZ-PFKFB3-67 quarterhydrate | ||
AZ-PFKFB3-67 quarterhydrate 是一种选择性的、高效的代谢激酶 PFKFB3 激酶抑制剂,作用于 PFKFB3 (IC50: 11 nM)、PFKFB2 (IC50: 159 nM) 和 PFKFB1 (IC50: 1130 nM)。 | |||
T26730 | AZ-PFKFB3-67 | ||
AZ-PFKFB3-67 is a novel, potent and selective inhibitor of PFKFB3. | |||
T25294 |
DCFBC F-18
18F-DCFBC |
||
DCFBC F-18 is a radioconjugate containing a low molecular weight tracer, DCFBC, specific for prostate-specific membrane antigen (PSMA) and labeled with the positron-emitting isotope F 18 with potential prostate tumor imaging upon positron emission tomogra | |||
T29689 |
AFB1-N7-guanine
|
||
In epidemiological studies, Aflatoxin B1-N7-guanine serum albumin adducts have been established as biomarkers of dietary aflatoxin exposure. | |||
T60312 |
FBPase-IN-1
|
||
FBPase-IN-1 is a powerful inhibitor of Fructose-1,6-bisphosphatase (FBPase), a key enzyme involved in Type 2 diabetes (T2D) research. It exhibits an impressive IC50 value of 0.22 μM. Aside from its potency, FBPase-IN-1 also demonstrates the ability to effectively lower blood glucose levels and improve glucose tolerance. Its mechanism of action involves covalently modifying the C128 site, thereby influencing the N125-S124-S123 allosteric pathway of FBPase, ultimately impacting its catalytic activ... | |||
T25293 |
DCFBC
|
||
DCFBC is a low-molecular-weight radiotracer. It targets prostate-specific membrane antigen (PSMA). | |||
T38165 |
FBBBE
|
||
FBBBE is a derivatized fluorescein compound that is used to detect the production hydrogen peroxide (H2O2) by cells. Intracellular H2O2, but not extracellular H2O2, initiates the conversion of FBBBE to fluorescein, resulting in an increase in intracellular fluorescence (excitation/emission maxima: 480/512 nm). | |||
T13138 |
TGFBR1-IN-1
|
ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
TGFBR1-IN-1 is an inhibitor of ALK5 (IC50 of 10-100 nM). | |||
T82635 |
Cy-FBP/SBPase-IN-1
|
||
Cy-FBP/SBPase-IN-1(compound S5)是一种针对蓝藻光合作用调节酶的Cy-FBP/SBPase抑制剂。该化合物能有效阻断卡尔文循环和光系统,从而减少蓝藻的光合效率。此外,Cy-FBP/SBPase-IN-1能抑制包括集胞藻PCC6803在内的蓝藻生长,并在人源细胞与斑马鱼模型中表现出良好的安全性。 | |||
T61818 | DFBTA | ||
DFBTA is a highly effective and orally active inhibitor of ANO1, specifically the calcium-activated chloride channel anoctamin-1. It exhibits potent inhibitory activity, with an IC 50 of 24 nM. Notably, DFBTA demonstrates significant analgesic efficacy in treating inflammatory pain [1]. | |||
T60294 | FBPase-IN-2 | ||
FBPase-IN-2 (HS36) 是一种有效的果糖-1,6-二磷酸酶 (FBPase) 共价抑制剂,IC50值为 0.15 μM。FBPase-IN-2 可减少肝细胞内葡萄糖的产生,可用于二型糖尿病的研究。 | |||
T78328 |
Efbemalenograstim alfa
F 627,Bineuta,Benegrastim |
||
Efbemalenograstim alfa(F 627)为重组长效二聚体G-CSF,融合了两个人源G-CSF与人免疫球蛋白G2(hIgG2)-Fc片段,并能有效促进白细胞生成。 | |||
T23454 |
TFB-TBOA
|
Others | Others |
glial glutamate transporter EAAT1 and EAAT2 inhibitor | |||
T62694 |
(S)-GFB-12811
|
||
(S)-GFB-12811 (compound 596) 是一种选择性的、选择性的 CDK5 抑制剂 (IC50<10 nM)。(S)-GFB-12811 能够用于细胞周期进程、神经元发育、肿瘤发生的研究。 | |||
T24576 |
OXFBD03
OXFBD-03,OXFBD 03 |
||
OXFBD03 is the bromodomain and extra terminal domain bromodomain family member BRD4(1) inhibitor. | |||
T60684 |
FBA-IN-1
|
||
FBA-IN-1 (compound 2a11) 是首创的,对白色念珠菌的 1,6-二磷酸果糖醛缩酶 (CaFBA) 的共价变构抑制剂。此外,FBA-IN-1 以 MIC80为 1 μg/mL,抑制唑类耐药菌株 103 的生长。 | |||
T82413 |
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
|
AUTACs | PROTAC |
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2为AUTAC4的连接体,其结构由一个p-氟苄鸟嘌呤(FBnG)部分和一个苯基吲哚部分组成,能够在HeLa细胞内诱导K63连结的多泛素化以及细胞线粒体的降解。 | |||
T9189 |
Iptacopan hydrochloride
Iptacopan HCl,LNP023 hydrochloride |
Complement System | Immunology/Inflammation |
Iptacopan hydrochloride (LNP023 hydrochloride) 是一种可口服、高效和高选择性的因子 B 抑制剂,IC50 为 10 nM。 LNP023 显示与人因子 B 的直接、可逆和高亲和力结合,KD 为 7.9 nM。 | |||
T11864 |
Iptacopan
LNP023 |
Others | Others |
Iptacopan (LNP023) 是一种与factor B 亲和力较高的抑制剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7926 |
Carmoisine
Azo Rubine,Chromotrope FB,偶氮玉红,铬变素FB |
Others | Others |
Carmoisine (Azo Rubine) 是一种可用作食品添加剂的偶氮染料。 | |||
T2988 |
(-)-Epigallocatechin Gallate
Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG |
Ferroptosis; Reactive Oxygen Species; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
(-)-Epigallocatechin Gallate (EGCG) 是茶类黄酮,具有强大的抗氧化,抗炎和抗癌作用。它可抑制EGFR 信号传导,有抗癌作用。它是谷氨酸脱氢酶 1/2 抑制剂。它通过激活细胞色素c 氧化酶来诱导氧化磷酸化。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04921 |
Complement factor B/CFB Protein, Human, Recombinant (His)
ARMD14,GBG,AHUS4,PBF2,complement factor B,FBI12,BF,... |
Human | HEK293 Cells |
Complement factor B/CFB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and the accession number is AAH04143.1. | |||
TMPH-00184 |
Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His)
cryIF(b),Crystaline entomocidal protoxin,Insecticidal delta-... |
Bacillus thuringiensis subsp. morrisoni | E. coli |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects. Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.3 kDa and the accession number is O66377. | |||
TMPY-06553 |
CXCR4 Protein, Human, Recombinant
NPYY3R,chemokine (C-X-C motif) receptor 4,D2S201E,HM89,NPYRL... |
Human | HEK293 Cells |
CXCR4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.75 kDa and the accession number is P61073-1. | |||
TMPK-00305 |
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,t... |
Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. | |||
TMPY-05157 |
TGFBR2 Protein, Human, Recombinant (His)
LDS2B,FAA3,TAAD2,MFS2,TGFR-2,TGFbeta-RII,transformi... |
Human | Baculovirus Insect Cells |
TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173. | |||
TMPY-01009 |
TGFBI Protein, Human, Recombinant (His)
CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be... |
Human | HEK293 Cells |
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys... | |||
TMPY-00836 |
IGFBP-4 Protein, Human, Recombinant (His)
HT29-IGFBP,IBP4,BP-4,IGFBP-4,insulin-like ... |
Human | HEK293 Cells |
IGFBP-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is A0A024R1U8. | |||
TMPY-04508 |
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc)
insulin-like growth factor binding protein 7,Mac25,AGM,Fstl2 |
Mouse | HEK293 Cells |
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.3 kDa and the accession number is A0A5E1. | |||
TMPY-02533 |
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His)
insulin-like growth factor binding protein 7,PSF,IGFB |
Human | HEK293 Cells |
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q16270. | |||
TMPY-04644 |
PDGFB Protein, Human, Recombinant (His)
platelet-derived growth factor beta polypeptide,SSV,c-sis,SI... |
Human | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted... | |||
TMPY-00835 |
IGFBP-3 Protein, Human, Recombinant (His)
insulin-like growth factor binding protein 3,IBP3,BP-53,IG |
Human | HEK293 Cells |
IGFBP-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is P17936-1. | |||
TMPY-05206 |
IGFBP-5 Protein, Human, Recombinant (His)
insulin-like growth factor binding protein 5,IBP5 |
Human | Baculovirus Insect Cells |
IGFBP-5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 30 kDa and the accession number is P24593. | |||
TMPY-02118 |
IGFBP-6 Protein, Mouse, Recombinant (His)
IGFBP-6,insulin-like growth factor binding protein ... |
Mouse | HEK293 Cells |
IGFBP-6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P47880. | |||
TMPJ-00335 |
TGFBR2 Protein, Mouse, Recombinant (His)
TGFR-2,TGF-beta type II receptor,Transforming growth factor-... |
Mouse | HEK293 Cells |
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2. | |||
TMPY-02295 |
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc)
IGFBP-7,IGFBPRP1,IBP-7,TAF,FSTL2,PSF,insul... |
Human | HEK293 Cells |
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.5 kDa and the accession number is Q16270. | |||
TMPK-00306 |
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFbetaRI,TGFBR1,ALK-5,SKR4,LDS2A,TGFB... |
Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is... | |||
TMPK-00329 |
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
LDS2B,TbetaR-II,TGFβR2,LDS2,RIIC,TGF-β RII/TGFBR2,T... |
Human | HEK293 Cells |
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi... | |||
TMPJ-00334 |
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TGF-β receptor type II,Tgfbr2,TGF-β receptor type-2... |
Mouse | HEK293 Cells |
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2. | |||
TMPJ-00319 |
PFKFB3 Protein, Human, Recombinant (His)
PFK/FBPase 3,PFK2,IPFK2,iPFK-2 |
Human | E. coli |
Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1) to regulate glycolysis and gluconeogenesis. Highly phosphorylated PFKFB3 protein was found in human tumor cells, vascular endothelial cells, and smooth muscle cells. Because of its proto-oncogenic c... | |||
TMPH-01327 |
FBXO48 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
FBXO48 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.7 kDa and the accession number is Q5FWF7. | |||
TMPK-01027 |
IGFBP-7 Protein, Mouse, Recombinant (hFc)
TAF,RAMSVPS,IBP7,PSF,IGFBP-7,MAC25,IGFBPRP... |
Mouse | HEK293 Cells |
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Mouse, Recombinant (hFc) is expres... | |||
TMPY-00837 |
IGFBP-4 Protein, Mouse, Recombinant (His)
Deb2,IGFBP-4,insulin-like growth factor binding pro... |
Mouse | HEK293 Cells |
IGFBP-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession number is P47879. | |||
TMPJ-00164 |
IGFBP-5 Protein, Human, Recombinant (His & Avi), Biotinylated
IBP-5,IBP5,IGF-Binding Protein 5,IGFBP5,Insulin-Lik... |
Human | HEK293 Cells |
Insulin-Like Growth Factor-Binding Protein 5 (IGFBP-5) is a secreted protein that belongs to the insulin-like growth factor (IGF) binding proteins superfamily. Members of this family prolong the half-life of the IGFs. They have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP-5 contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP-5 is expressed... | |||
TMPJ-01166 |
IGFBP-7 Protein, Mouse, Recombinant (His)
TAF,IGFBP-rP1,Insulin-like growth factor-binding pr... |
Mouse | HEK293 Cells |
Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase inhibitor domain and a C-terminal immunoglobulin-like C2-type domain. Human and mouse IGFBP7 are highly homologous and share 94% aa sequence identity. It is expressed in many normal tissues and in cancer cells. It is abundantly expressed in high endothelial venules (HEVs) of bloo... | |||
TMPY-04877 |
PDGFB Protein, Mouse, Recombinant (His)
platelet-derived growth factor β polypeptide,血小板源生长因子,Sis,pl... |
Mouse | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted... | |||
TMPK-01077 |
IGFBP-3R Protein, Human, Recombinant (hFc)
TMEM219,IGFBP-3R,LOC124446,GFBP3R |
Human | HEK293 Cells |
IGFBP-3R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.5 kDa and the accession number is Q86XT9. | |||
TMPK-00838 |
IGFBP-2 Protein, Human, Recombinant (His)
mIGFBP-2,IGFBP-2,IGF-BP53,IBP-2,BP2,AI2558... |
Human | HEK293 Cells |
IGFBP-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 32.5 kDa and the accession number is P18065. | |||
TMPH-02544 |
DEFB4 Protein, Mouse, Recombinant (His & SUMO)
Bdef4,BD-4,Beta-defensin 4,Defensin, beta 4,mBD-4,Defb |
Mouse | E. coli |
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. DEFB4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 20.6 kDa and the accession number is P82019. | |||
TMPY-02224 |
TGFBR3 Protein, Mouse, Recombinant (His)
transforming growth factor, β receptor III,TBRIII,AW215636,t... |
Mouse | HEK293 Cells |
TGFBR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.3 kDa and the accession number is A0A0R4J097. | |||
TMPY-06879 |
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His)
Mac25,insulin-like growth factor binding protein 7,AGM,Fstl2 |
Mouse | HEK293 Cells |
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.69 kDa and the accession number is AAH92538.1. | |||
TMPY-02920 |
IGFBP-1 Protein, Rhesus, Recombinant (His)
insulin-like growth factor binding protein 1 |
Rhesus | HEK293 Cells |
IGFBP-1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A0A1D5QTL3. | |||
TMPY-03216 |
GMF beta/GMFB Protein, Human, Recombinant
GMF β/GMFB,glia maturation factor, β,glia maturatio... |
Human | E. coli |
GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis and immune function. It is especially crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. It contains 1 ADF-H domain and is phosphorylated after phorbol ester stimulation. GMFB overexpression in astrocytes results in the increase of BDNF production... | |||
TMPY-01115 |
DEFB119 Protein, Human, Recombinant (mFc)
DEFB-20,DEFB120,DEFB19,ESC42-RELB... |
Human | HEK293 Cells |
DEFB119 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 33.9 kDa and the accession number is Q8N690-1. | |||
TMPJ-01243 |
DEFB4 Protein, Human, Recombinant
DEFB4,DEFB104B,hBD-4,DEFB104,BD-4... |
Human | E. coli |
Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursor... | |||
TMPY-00080 |
IGFBP-1 Protein, Canine, Recombinant (His)
insulin-like growth factor binding protein 1 |
Canine | HEK293 Cells |
IGFBP-1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A0A8C0MZD6. | |||
TMPY-05508 |
TGFBR2 Protein, Human, Recombinant (hFc)
TGFβ-RII,TGFbeta-RII,MFS2,AAT3,transforming growth ... |
Human | HEK293 Cells |
TGFBR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is P37173. | |||
TMPJ-01178 |
TGFBR1 Protein, Mouse, Recombinant (hFc)
ALK-5,ALK-5ALK5,TGFβRI,tβR-I,LDS1A,TGFbetaRI,TG... |
Mouse | HEK293 Cells |
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Phosphorylated TGF-beta RI can then transiently bind and phosphorylate Smad2 and Smad3. TGF-beta functions as a tumor suppressor by inhibiting the cell cycle in the G1 phase. Administration of TGF-beta is able to protect against mammary tumor development in transgenic mouse models i... | |||
TMPY-05810 |
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated
RIIC,TAAD2,AAT3,TGFβ-RII,FAA3,transforming growth factor, β ... |
Human | HEK293 Cells |
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P37173. | |||
TMPJ-00024 |
GMF beta/GMFB Protein, Human, Recombinant (His)
GMF-β,GMF-beta,GMFB,Glia maturation factor beta,Gli... |
Human | E. coli |
Glia maturation factor beta (GMFB) contains a ADF-H domain,which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results... | |||
TMPJ-00003 |
DEFB1 Protein, Human, Recombinant
Beta-Defensin 1,BD-1,HBD1,Defensin β1,BD1,Defensin Beta 1,β-... |
Human | E. coli |
β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis,... | |||
TMPH-03315 |
IGFBP-1 Protein, Rat, Recombinant
|
Rat | E. coli |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. IGFBP-1 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26.9 kDa and the accession number is P21743. | |||
TMPH-02542 |
DEFB19 Protein, Mouse, Recombinant (His & Myc)
Defensin, beta 19,Tdl,Testis-specific beta-defensin-like pro... |
Mouse | E. coli |
Has antibacterial activity. | |||
TMPH-00335 |
FBA1 Protein, Candida albicans, Recombinant (His & Myc)
|
Candida albicans | E. coli |
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. FBA1 Protein, Candida albicans, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9URB4. | |||
TMPY-05473 |
KSP37/FGFBP2 Protein, Human, Recombinant (His)
HBP17RP,fibroblast growth factor binding protein 2,KSP37 |
Human | Baculovirus Insect Cells |
KSP37/FGFBP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 22.6 kDa and the accession number is Q9BYJ0. | |||
TMPJ-00815 |
FBPase1 Protein, Human, Recombinant (His, E. coli)
6-Bisphosphate 1-Phosphohydrolase 1,FBP1,FB |
Human | E. coli |
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young chi... | |||
TMPY-04319 |
IGFBP-2 Protein, Mouse, Recombinant (hFc)
insulin-like growth factor binding protein 2, 36kDa,IBP-2,mI... |
Mouse | HEK293 Cells |
IGFBP-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.6 kDa and the accession number is P47877. | |||
TMPY-03249 |
IGFBP-4 Protein, Cynomolgus, Recombinant (His)
insulin-like growth factor binding protein 4 |
Cynomolgus | HEK293 Cells |
IGFBP-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa. | |||
TMPY-02395 |
PDGFB Protein, Cynomolgus, Recombinant (mFc)
血小板源生长因子,platelet-derived growth factor beta polypeptide,pla... |
Cynomolgus | HEK293 Cells |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with ... | |||
TMPY-03504 |
CBFB Protein, Human, Recombinant (His)
core-binding factor, β subunit,core-binding factor, beta sub... |
Human | E. coli |
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). CBFB is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enh... | |||
TMPH-02545 |
DEFB6 Protein, Mouse, Recombinant (His & KSI)
Defb6,Beta-defensin 6,Defensin, beta 6,mBD-6,BD-6 |
Mouse | E. coli |
Has potent antibacterial activity against E.coli (ATCC 25922). DEFB6 Protein, Mouse, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.8 kDa and the accession number is Q91VD6. | |||
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