106
25
40
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8752 |
BAR 501 impurity
|
GPCR19 | GPCR/G Protein |
BAR 501 impurity 在 BAR501 制剂中发现的一种杂质,可作为 G 蛋白偶联胆汁酸激活受体 (GP-BAR1) 的激动剂。 BAR501 杂质 (10 µM) 在 GP-BAR1 报告基因检测中诱导荧光素酶活性增加 150%。 | |||
T4083 |
BAR501
BAR 501 |
GPCR19 | GPCR/G Protein |
BAR501是高效选择性的 GPBAR1激动剂(EC50:1 μM)。 | |||
TQ0252 |
BAR502
|
FXR; GPCR19; Autophagy | Autophagy; GPCR/G Protein; Metabolism |
BAR502 是一种 GPBAR1 和 FXR 双重激动剂,IC50分别为0.4 μM 和 2 μM。 | |||
T5856 |
Barnidipine hydrochloride
盐酸巴尼地平,YM-09730-5 hydrochloride,Mepirodipine (hydrochloride) |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Barnidipine hydrochloride (YM-09730-5 hydrochloride) 是一种二氢吡啶类钙通道阻滞剂,对 CaA 受体具有选择性作用。它是一种抗高血压药物,通过减少其血管扩张作用继发的外周血管阻力起作用。 | |||
T2602 |
Barasertib-HQPA
1H-Pyrazole-3-acetamide,Barasertib,AZD1152-HQPA,AZD2811,AZD1152-HQPA|AZD2811 |
Apoptosis; Aurora Kinase | Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic |
Barasertib-HQPA (AZD2811) 是一种高度选择性的极光激酶B 抑制剂,在非细胞试验中IC50值为0.37 nM。它可阻滞癌细胞生长,诱导凋亡。 | |||
T20018 |
Barium lithol red
HSDB 5523,立索尔大红,PR-258,Barium lithol,1883 red |
Others | Others |
Barium lithol red (HSDB 5523) 是一种透明的蓝色调红色颜料,主要应用于印墨着色。 | |||
T6694 |
Tamibarotene
NSC 608000,Am 80,Amnolake,他米巴罗汀 |
Apoptosis; Retinoid Receptor; Autophagy | Apoptosis; Autophagy; Metabolism |
Tamibarotene (Amnolake) 是一种具有口服活性的合成维甲酸,旨在克服全反式维甲酸耐药性,具有潜在的抗肿瘤活性。它也是视黄酸受体α/β 的激动剂,比RARγ的选择性高。 | |||
T2485 |
Baricitinib
INCB028050,LY3009104,巴瑞克替尼 |
Tyrosine Kinases; JAK; Chk | Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Baricitinib (INCB028050) 是一种选择性,可口服的JAK1和JAK2抑制剂,IC50分别为5.9 nM 和 5.7 nM,具有潜在的抗炎、免疫调节和抗肿瘤活性。 | |||
T7550 |
Barnidipine
YM-09730-5(Free base),(4S)-2,6-二甲基-4-(间硝基苯基)-1,4-二氢吡啶-3,5-二羧酸 (3S)-1-苄基-3-吡咯烷基-甲基酯,Mepirodipine |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Barnidipine (YM-09730-5(Free base)) 是一种二氢吡啶类钙通道阻滞剂,对 CaA 受体具有选择性作用。它是一种抗高血压药物,通过减少其血管扩张作用继发的外周血管阻力起作用。 | |||
T6165 |
Bardoxolone Methyl
RTA 402,CDDO Methyl ester,TP-155,甲基巴多索隆,NSC 713200 |
Apoptosis; IκB/IKK; Ferroptosis; Nrf2; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; NF-κB |
Bardoxolone Methyl (TP-155) 是一种合成的三萜类化合物,作为 Nrf2通路的激活剂和 NF-κB 途径的抑制剂,具有潜在的抗肿瘤和抗炎活性。 | |||
T2360 |
Baricitinib phosphate
Baricitinib Phosphate,LY3009104,磷酸巴瑞克替尼,INCB-028050 phosphate,LY-3009104 phosphate,INCB028050 |
Tyrosine Kinases; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Baricitinib phosphate (INCB028050) 是一种选择性的,可口服的 JAK1/JAK2抑制剂,IC50值分别为 5.9 和 5.7 nM。 | |||
T0790 |
Carbaryl
1-naphthyl methylcarbamate,甲萘威,Sevin |
AChR | Neuroscience |
Carbaryl (1-naphthyl methylcarbamate) 可作为一种杀虫剂。 | |||
T14371 |
Barasertib
巴拉塞替,AZD1152 |
Apoptosis; Aurora Kinase | Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic |
Barasertib (AZD1152) 是 Barasertib-hQPA 的前体药物,在癌细胞中诱导生长停滞和凋亡。它是高度选择性的Aurora B 抑制剂,IC50值为 0.37 nM。 | |||
T72282 |
Ebaresdax hydrochloride
|
Endogenous Metabolite | Metabolism |
Ebaresdax hydrochloride 具有镇痛活性,,可用于研究由I型或II型糖尿病引起的糖尿病性神经病变疼痛。 | |||
T10002 |
(E)-Crotylbarbital
Kalypnon |
Others | Others |
(E)-Crotylbarbital (Kalypnon) 是Crotylbarbital 的异构体,是一种巴比妥酸衍生物,具有镇静、催眠和抗惊厥的作用。(E)-Crotylbarbital 可用于促进精神安定和睡眠的研究。 | |||
T10217L |
Abarelix
R3827,阿巴瑞克,PPI 149 |
GNRH Receptor | GPCR/G Protein |
Abarelix (PPI 149) 是一种促性腺激素释放激素 (GnRH) 拮抗剂,用于前列腺癌研究。 | |||
TP1267L |
CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 acetate
CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 acetate(254110-79-7 free base) |
Others | Others |
CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 acetate(254110-79-7 free base) 对应于 BRLF1 的氨基酸 148-156。 BRLF1 是一种转录激活因子,可直接与一些 Epstein-Barr 病毒 (EBV) 裂解基因启动子中的富含 GC 的基序结合。 | |||
T74424 | Masavibart | ||
Masavibart (ZRC3308-A7) 是一种靶向SARS-CoV-2的单克隆抗体 (IgG1 型)。Masavibart 对SARS-CoV-2穗状蛋白的RBD 上的非竞争性表位显示出良好的结合亲和力。Masavibart 可按 1:1 与ZRC3308-B10 联合使用,对 COVID-19 的预防以及尚未发展为严重疾病的早期 COVID-19 有效。 | |||
T74426 | Ogalvibart | ||
Ogalvibart (C-135-LS)为人源化抗SARS-CoV-2单克隆抗体(IgG1型),能够与SARS-CoV-2的S蛋白RBD紧密结合。当与C144LS以1:1比例联合使用时,Ogalvibart显示出优异的预防活性,能有效预防恒河猴疾病模型中COVID-19的发展。 | |||
T76878 | Vobarilizumab | ||
Vobarilizumab (ALX-0061) 是一种抗 IL-6R 单克隆抗体 (mAb) (Kd: 0.19 pM)。Vobarilizumab 由一个抗 IL-6R 结构域和一个抗人血清白蛋白结构域组成。Vobarilizumab 可用于炎症性自身免疫性疾病的研究,如类风湿性关节炎。 | |||
TP1268 |
CEF19, Epstein-Barr Virus latent NA-3A (458-466)
CEF19,Epstein-Barr Virus latent NA-3A 458-466 |
||
CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain). | |||
T80560 |
Tulisokibart
PRA-023,PRA023 |
||
Tulisokibart (PRA023)为人源化小鼠IgG1-κ型单克隆抗体,专一性靶向TNFSF15/TL1A。应用于炎症及纤维化疾病如克罗恩病(Crohn's Disease, CD)的研究。 | |||
T22669 |
Cinnabarinic acid
|
Others | Others |
mGlu4 receptor agonist | |||
T37388 |
Afizagabar
|
||
Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy[1]. Afizagabar (S44819) is a competitive α5-GABAAR antagonist (Kb=221 nM). Afizagabar selectively inhibits extrasynaptic α5-GABAARs of mouse CA1 pyramidal neurons[1]. Afizagabar (1 and 3 mg/kg; i.p.) significantly diminishes t... | |||
T71811 |
Lobaric acid
|
||
Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites. It scavenges superoxide radicals in a cell-free assay (IC50 = 97.9 μmol) and inhibits proliferation in a panel of leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic, and lung cancer cell lines (EC50s = 15.2-63.9 μg/ml). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50 = 0.87 μM for the h... | |||
T31345 |
Decanoic acid, barium salt
Decanoic acid, barium salt (2:1),Barium decanoate |
||
Decanoic acid, barium salt is a biochemical. | |||
T124772 |
Crobarbatine
|
||
Crobarbatine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124772。 | |||
T82615 |
Dalnicastobart
LVGN-7409 |
||
Dalnicastobart (LVGN-7409) 是一种针对CD40/TNFRSF5的人源化IgG1κ单克隆抗体。 | |||
T82021 |
Izeltabart
IMGC-936 |
||
Izeltabart(IMGC-936)是一款针对ADAM9的基于Maytansinoid的ADC,由与DM21-C位点特异性偶联的高亲和力人源化抗体构成,使Maytansinoid微管破坏载体通过稳定的三肽连接子进行传递,达到药物-抗体比约为2.0。Izeltabart在ADAM9阳性人类肿瘤细胞系上显示出明显的细胞毒性,并在动物异种移植肿瘤模型中展现出显著的抗肿瘤效果。 | |||
T81510 |
Perenostobart
|
||
Perenostobart为一人源化免疫球蛋白G4-kappa,针对ENTPD1/CD39的单克隆抗体。该化合物兼具免疫刺激剂与抗肿瘤药物的特性。 | |||
T81098 |
Stapokibart
CM310 |
||
Stapokibart (CM310) 是一款针对IL-4Rα的人源化单克隆抗体,有效抑制IL-4及IL-13与该受体亚基的结合。该药物对人类、食蟹猴和大鼠的IL-4Rα都有作用。 | |||
T81925 |
Lixudebart
|
||
Lixudebart为人源化IgG1-kappa亚型抗CLDN1单克隆抗体。 | |||
T80868 |
Verzistobart
|
||
Verzistobart 为针对甲型肝炎病毒细胞受体HAVCR2的 IgG1κ单克隆抗体。 | |||
T125861 |
Sodium barbital
|
||
Sodium barbital 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125861。 | |||
T76918 | Barecetamab | ||
Barecetamab (ISU-104) 是一种人源话抗 ErbB3单克隆抗体。Barecetamab 可用于复发/转移性 (R/M) 头颈部鳞状细胞癌 (HNSCC) 的研究。 | |||
T76733 | Enibarcimab | ||
Enibarcimab 是一种人源化小鼠单克隆免疫球蛋白 G1 (IgG1) 抗体,可用于急性心衰、COVID 2019 感染和感染性休克的研究。 | |||
T14498 |
Barbadin
|
Arrestin | GPCR/G Protein |
Barbadin 是一种新型且具有特异性的 β-arrestin/β2-adaptin 相互作用抑制剂,对β-arestin1 的 IC50 值为 19.1 μM,对β-arestin2 的 IC50 值为 15.6 μM。Barbadin 增强氯卡色林对 POMC 神经元和减肥的长期影响,可阻断激动剂促进的原型 β2-肾上腺素能、V2-血管加压素和血管紧张素-II-1 型受体的内吞,可用于研究肥胖。 | |||
TP1267 |
CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156)
CEF27,Epstein-Barr Virus BRLF-1 lytic 148-156 |
||
HLA-A*0301-restricted epitope from Epstein-Barr Virus , EBV BRLF-1 (148-156). | |||
T80575 |
Simaravibart
MAD-0004J08 |
SARS-CoV | Microbiology/Virology |
Simaravibart (MAD-0004J08) 是一种IgG1κ 抗体,靶向SARS-CoV-2刺突(S)糖蛋白的受体结合域。 | |||
T80577 |
Varokibart
|
||
Varokibart (TEV-53275)为针对IL-5的人源化IgG4λ单克隆抗体。 | |||
T31451 |
Difebarbamate
|
||
Difebarbamate is a biochemical. | |||
T124815 |
Barbaloin-related compound A
|
||
Barbaloin-related compound A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124815。 | |||
T81022 |
Tegoprubart
|
||
Tegoprubart为针对CD40配体(CD40L)的单克隆抗体,该配体为共刺激介质的核心。通过抑制CD40L,可减弱细胞与抗体介导的免疫反应,促进免疫环境趋向耐受性。在移植动物模型中,Tegoprubart已展现出体内活性。 | |||
T80903 |
Ulviprubart
ABC-008 |
||
Ulviprubart是一种Anti-KLRG1 mAb,适用于研究多种疾病。 | |||
T80902 |
Umesolerbart
|
||
Umesolerbart (REGN5714) 是一种特异性针对Bet v1的mAb。它能结合于桤木科植物、榛树和鹅耳枥相关的同源过敏原。 | |||
T37989 |
D-Sedoheptulose-7-phosphate (barium salt)
|
||
D-Sedoheptulose-7-phosphate is an intermediate in the pentose phosphate pathway. [1] [2] In this pathway, transaldolase catalyzes the transfer of a three carbon dihydroxyacetone moiety from D-sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to generate D-fructose-6-phosphate . D-Sedoheptulose-7-phosphate is also an intermediate in carbon fixation in photosynthetic organisms, as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics. [3] | |||
T82371 |
Freneslerbart
|
||
Freneslerbart为针对Felcat allergen 1的IgG4κ类抗体,后者为一过敏原蛋白。 | |||
T82946 |
Atisnolerbart
|
||
Atisnolerbart为一种靶向BETVIA的人源IgG4抗体,其中BETVIA指的是桦树花粉过敏原Bet v 1-A的主要成分。 | |||
T82440 |
Erzotabart
|
CD38 | Immunology/Inflammation |
Erzotabart为一IgG1-kappa型人源单克隆抗体,针对CD38(ADP-核糖环化酶 1,环 ADP-核糖水解酶 1,cADPr 水解酶 1,cADPR1)。该化合物展现出抗肿瘤活性。 | |||
T81314 |
Rademikibart
CBP-201 |
||
Rademikibart (CBP-201) 是一款针对IL-4Rα的人源化单克隆抗体,其与人IL-4Rα的结合亲和力KD值为20.7 pM。该抗体不与其他物种的IL-4Rα发生交互作用。Rademikibart 能够抑制PBMC中IL-4及IL-13介导的STAT6信号通路、TF-1细胞的增殖以及TARC的产生,显示出其在中到重度Th2型炎症性疾病研究中的应用潜力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0176 |
Isobarbaloin
Aloin,Aloin-A,芦荟甙,Barbaloin-A |
Tyrosinase | Proteases/Proteasome |
Isobarbaloin (Barbaloin-A) 是一种来自芦荟的天然蒽环类药物,是一种酪氨酸酶抑制剂。 | |||
TN6770 |
Malabaricone A
|
Others | Others |
Malabaricone A 是一种生物活性化学物质。 | |||
T5S1632 |
Barlerin
8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01 |
VEGFR; TNF; NF-κB; Akt; Caspase | Angiogenesis; Apoptosis; Cytoskeletal Signaling; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Barlerin (8-O-Acetylshanzhiside methyl ester) 是一种环孢菌素葡萄糖苷,从中国西藏民间药用植物中分离得到,能够抑制NF-κB 活性。 | |||
T20550 |
Thiobarbituric acid
NSC4733,NSC 4733,4,6-二羟基-2-巯基嘧啶,NSC-4733 |
Antibacterial | Microbiology/Virology |
Thiobarbituric acid (NSC-4733) 具有抗菌活性。 | |||
T2915 |
Bardoxolone
RTA 401,齐墩果烷三萜化合物,CDDO |
Others; Nrf2 | Immunology/Inflammation; Others |
Bardoxolone (CDDO) 是新型核调节因子激活剂。 | |||
TN6771 |
Malabaricone B
|
Others | Others |
Malabaricone B 是一种源自香料的酚类物质,它通过不依赖 p53 的途径诱导肺癌细胞中的线粒体损伤。 | |||
TN6772 |
Malabaricone C
|
Others | Others |
Malabaricone C 是天然的鞘磷脂合成酶抑制剂,对 SMS 1 和 SMS 2 的IC50分别为 3 和 1.5 μM。 | |||
TN2192 | Scutebarbatine B | Others | Others |
Scutebarbatine B shows weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 μM against K562 cell lines and HL60 cell lines. | |||
TN5794 |
Dehydroherbarin
|
||
Dehydroherbarin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5794,CAS号为 36379-74-5。 | |||
TN2194 |
Scutebarbatine X
|
Others | Others |
Scutebarbatine X can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation. | |||
TN3490 |
Barbinervic acid
|
Antifection | Microbiology/Virology |
Barbinervic acid shows anti-bacteria activity (IC50 = 0.098 g x LU(-1), IC50 = 0.27 g x L(-1)) against SA and ESBLs-SA respectively. | |||
TN2191 |
Scutebarbatine A
|
BCL; Caspase | Apoptosis; Proteases/Proteasome |
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2. Scutebarbatine A and barbatine A show a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 μM, respectively. | |||
TN1323 |
6-O-Nicotinoylbarbatin C
6-O-烟酰半枝莲素 C |
Others | Others |
6-O-Nicotinoylbarbatin C is a natural product | |||
TN3491 | Barpisoflavone A | Others | Others |
Barpisoflavone A possesses moderate estrogen partial agonistic activities and moderate antioxidant activities. | |||
TN5793 | Herbarin | ||
Herbarin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5793,CAS号为 36379-67-6。 | |||
TN1324 |
6-O-Nicotinoylscutebarbatine G
|
Others | Others |
6-O-Nicotinoylscutebarbatine G shows cytotoxic activities against three human tumor cell lines, namely, HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells, and with IC50 values in the range of 2.1 5.7 μM. | |||
TN5791 |
Herbaridine B
|
||
Herbaridine B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5791,CAS号为 1151511-05-5。 | |||
T81767 |
Monbarbatain A
|
||
Monbarbatain A, 一种二聚菲类化合物,可从兰科植物Monomeria barbata中提取。 | |||
TN2196 | Scutebarbatine Z | Others | Others |
Scutebarbatine Z is a natural product from Scutellaria barbata. | |||
T82921 |
Barbatic acid
|
||
Barbatic acid是一种具有活性的化合物。 | |||
T2S0605 |
Liquidambaric lactone
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Liquidambaric lactone 是一种分离自Euonymus grandiflorusWall 中的化合物。 | |||
TN3489 |
Barbacarpan
|
Others | Others |
Barbacarpan is a natural product from Crotalaria barbata. | |||
T23773 |
Barbigerone
Barubigeron |
||
Barbigerone is a tumor angiogenesis, growth, and metastasis inhibitor in melanoma. | |||
TN2193 |
Scutebarbatine W
|
Others | Others |
Scutebarbatine W can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation. | |||
TN2195 |
Scutebarbatine Y
|
Others | Others |
Scutebarbatine Y is a natural product from Scutellaria barbata. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00871 |
BAR Protein, S. hygroscopicus, Recombinant
bar,PPT N-acetyltransferase,Phosphinothricin-resist... |
Streptomyces hygroscopicus | E. coli |
Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant... | |||
TMPY-00411 |
Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | Baculovirus Insect Cells |
Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.6 kDa and the accession number is Q195D4. | |||
TMPY-06768 |
NR1H4 Protein, Human, Recombinant (His)
FXR,BAR,nuclear receptor subfamily 1, group H, memb... |
Human | E. coli |
NR1H4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.83 kDa and the accession number is Q96RI1-1. | |||
TMPY-01124 |
Influenza A H5N1 (A/bar-headed goose/Qinghai/14/2008) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | HEK293 Cells |
Influenza A H5N1 (A/bar-headed goose/Qinghai/14/2008) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.5 kDa and the accession number is B8YQI3. | |||
TMPY-03229 |
Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | HEK293 Cells |
Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is Q195D4. | |||
TMPY-00106 |
Influenza A H12N3 (A/bar headed goose/Mongolia/143/2005) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H12N3 | HEK293 Cells |
Influenza A H12N3 (A/bar headed goose/Mongolia/143/2005) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is D2JIV2. | |||
TMPY-00144 |
Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350 Protein (His)
BLLF1,gp22 |
EBV | Baculovirus Insect Cells |
Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.7 kDa and the accession number is A0A0B6VN60. | |||
TMPH-00539 |
Epstein-Barr virus (strain B95-8) BDLF3 Protein (His & Myc)
|
EBV | E. coli |
Epstein-Barr virus (strain B95-8) BDLF3 Protein (His & Myc) is expressed in E. coli. | |||
TMPY-04179 |
Influenza A H5N1 (A/barn swallow/Hong Kong/D10-1161/2010) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | HEK293 Cells |
Influenza A H5N1 (A/barn swallow/Hong Kong/D10-1161/2010) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.2 kDa and the accession number is L7S370. | |||
TMPH-00544 |
Epstein-Barr virus (strain B95-8) LMP2 Protein (His & SUMO)
|
EBV | E. coli |
Epstein-Barr virus (strain B95-8) LMP2 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.6 kDa and the accession number is P13285. | |||
TMPY-03803 |
Influenza A H5N1 (A/barnswallow/HongKong/D10-1161/2010) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | Baculovirus Insect Cells |
Influenza A H5N1 (A/barnswallow/HongKong/D10-1161/2010) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.2 kDa and the accession number is L7S370. | |||
TMPH-00542 |
Epstein-Barr virus (strain Raji) LMP1 Protein (His)
|
EBV | P. pastoris (Yeast) |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... | |||
TMPJ-00016 |
GABARAP Protein, Human, Recombinant (GST)
GABARAP,GABA(A) Receptor-Associated Protein,GAB... |
Human | E. coli |
GABARAP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37 KDa and the accession number is Q6IAW1. | |||
TMPH-00155 |
Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc)
Barstar,Ribonuclease inhibitor |
Bacillus amyloliquefaciens | E. coli |
Inhibitor of the ribonuclease barnase. Forms a one-to-one non-covalent complex. Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.7 kDa and the accession number is P11540. | |||
TMPH-00446 |
CCHF virus (strain Nigeria/IbAr10200/1970) Envelopment polyprotein (His & MBP)
GP,Envelopment polyprotein,M polyprotein |
CCHFV | E. coli |
CCHF virus (strain Nigeria/IbAr10200/1970) Envelopment polyprotein (His & MBP) is expressed in E. coli. | |||
TMPH-00548 |
Epstein-Barr virus (strain B95-8) BZLF1 Protein (His & SUMO)
|
EBV | E. coli |
Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 activates the promoter of another EBV gene (BSLF2+BMLF1). | |||
TMPH-00538 |
Epstein-Barr virus (strain GD1) EBNA3 Protein (His & Myc)
|
EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. | |||
TMPY-06899 |
Epstein-Barr virus (EBV) (strain B95-8) gH & gL Heterodimer Protein (His & Flag)
|
EBV | HEK293 Cells |
Epstein-Barr virus (EBV) (strain B95-8) gH & gL Heterodimer Protein (His & Flag) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 89.51 kDa and the accession number is P03231. | |||
TMPH-02461 |
pylS Protein, Methanosarcina barkeri, Recombinant (His)
|
Methanosarcina barkeri | E. coli |
Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. pylS Protein, Methanosarcina barkeri, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.8 kDa and the accession number is Q46E77. | |||
TMPH-00546 |
Epstein-Barr virus (strain GD1) BARF1 Protein (His)
|
EBV | E. coli |
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. | |||
TMPY-06322 |
Epstein-Barr virus (B95-8) Glycoprotein gp350 Protein (His & Avi), Biotinylated
gp22,BLLF1 |
EBV | HEK293 Cells |
Epstein-Barr virus (B95-8) Glycoprotein gp350 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 55.51 kDa and the accession number is YP_401667.1. | |||
TMPH-00550 |
Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc)
|
EBV | E. coli |
Plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. Inhibits IFN-gamma synthesis. Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted m... | |||
TMPH-00543 |
Epstein-Barr virus (strain Raji) LMP1 Protein (His & SUMO)
|
EBV | E. coli |
Epstein-Barr virus (strain Raji) LMP1 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.0 kDa and the accession number is P13198. | |||
TMPH-00549 |
Epstein-Barr virus (strain GD1) BZLF1 Protein (His & Myc)
|
EBV | E. coli |
Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 activates the promoter of another EBV gene (BSLF2+BMLF1). | |||
TMPY-03461 |
GABARAPL2 Protein, Human, Recombinant (His)
GATE16,ATG8,ATG8C,GEF-2,GATE-16,GEF2,GABA(A) receptor-associ... |
Human | E. coli |
GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. | |||
TMPH-00547 |
Epstein-Barr virus (strain B95-8) BARF1 Protein (His & Myc)
|
EBV | E. coli |
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. | |||
TMPH-00540 |
Epstein-Barr virus (strain GD1) LMP1 Protein (His)
|
EBV | P. pastoris (Yeast) |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... | |||
TMPH-00191 |
Barmah forest virus (BFV) p130 Protein
p130,Structural polyprotein |
BFV | E. coli |
Barmah forest virus (BFV) p130 Protein is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 50.7 kDa and the accession number is P89946. | |||
TMPY-00556 |
Influenza A H5N1 (A/barnswallow/HongKong/D10-1161/2010) Hemagglutinin Protein (HA1+HA2, His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | Baculovirus Insect Cells |
Influenza A H5N1 (A/barnswallow/HongKong/D10-1161/2010) Hemagglutinin Protein (HA1+HA2, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.8 kDa and the accession number is L7S370. | |||
TMPH-00537 |
Epstein-Barr virus (strain B95-8) EBNA3 Protein (His & Myc)
|
EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. | |||
TMPH-00545 |
Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc)
|
EBV | E. coli |
Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency. Triggers lytic replication, and initiates a cellular senescence program in epithelial cells. Upregulates human DCR3/TNFRSF6B by directly binding to its receptor. Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is Q3KS... | |||
TMPJ-00015 |
GABARAP Protein, Human, Recombinant (His & hFc)
GABA(A) Receptor-Associated Protein,HCG1987397 Isoform CRA_b... |
Human | E. coli |
GABARAP Protein, Human, Recombinant (His & hFc) is expressed in E. coli expression system with N-6xHis and C-Fc tag. The predicted molecular weight is 50 KDa and the accession number is Q6IAW1. | |||
TMPH-00536 |
Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)
|
EBV | P. pastoris (Yeast) |
Plays a key role in the activation of the host resting B-cell and stimulation of B-cell proliferation. Acts by up-regulating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes including CD21, CD23 and MYC. Activates transcription by acting as an adapter molecule that binds to cellular sequence-specific DNA-binding proteins such as host CBF1, SMARCB1 and SPI1. Once EBNA2 is near promoter sites, its acidic activating domain recruits basal and activation-ass... | |||
TMPH-00541 |
Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)
|
EBV | E. coli |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... | |||
TMPH-00535 |
Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)
|
EBV | E. coli |
Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell. | |||
TMPY-03268 |
GABARAPL1 Protein, Human, Recombinant (His)
GEC1,APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GABA(A) receptor-assoc... |
Human | E. coli |
ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient deple... | |||
TMPY-00587 |
GABARAP Protein, Human, Recombinant (His & MBP)
GABARAP-a,GABA(A) receptor-associated protein,ATG8A... |
Human | E. coli |
The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. GABARAPs as the first known direct interaction partners of Nef that are essential... | |||
TMPH-02301 |
VPS35 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of... | |||
TMPY-02300 |
BIN1 Protein, Human, Recombinant (His)
AMPHL,bridging integrator 1,AMPH2,SH3P9 |
Human | E. coli |
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicated in rare and common diseases affecting different tissues and physiological functions. BIN1 downregulation is linked to cancer progression and also correlates with ventricular cardiomyopathy and arrhythmia preceding heart failure. Increased BIN1 expression is linked to increased... | |||
TMPY-02384 |
MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)
metastasis suppressor 1,MIMB,MIM,MIMA |
Human | E. coli |
MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor... |