Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6S0141 |
Corylin
补骨脂异黄酮,补骨脂宁 |
Antibacterial; Antibiotic; STAT | JAK/STAT signaling; Microbiology/Virology; Stem Cells |
Corylin 是一种从补骨脂中分离的生物活性化合物,有抗生素或抗癌作用。 | |||
T5747 |
ISOBERGAPTEN
|
Others | Others |
Isobergapten 是一种化感抑制剂,分离自Hevacleum laciniatum 种子。 | |||
T3846 |
Bavachin
Corylifolin,补骨脂甲素,补骨脂二氢黄酮 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Bavachin (Corylifolin) 是一种从补骨脂种子中分离到的黄酮类物质,能够激活雌性激素受体 ERα (EC50:320 nM) 和 ERβ (EC50:680 nM)。 | |||
T3400 |
Bakuchiol
|
p38 MAPK; DNA/RNA Synthesis; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; MAPK |
Bakuchiol 是一种从补骨脂种子中提取的植物雌激素,具有抗肿瘤和抗蠕虫特性,以及细胞毒活性和抗菌活性。 | |||
T4S0145 |
Corylifol A
Corylinin,补骨脂异黄酮A |
hCE; STAT; UGT | JAK/STAT signaling; Metabolism; Stem Cells |
Corylifol A (Corylinin) 是补骨脂中的一种天然产物,可抑制IL-6 诱导的STAT3激活和磷酸化,IC50值为0.81 μM。 | |||
T2901 |
Daidzin
NPI-031D,大豆苷,Daidzein 7-O-glucoside,Daidzoside,黄豆苷,Daidzein 7-glucoside |
Dehydrogenase; Reverse Transcriptase; Mitochondrial Metabolism | Metabolism; Microbiology/Virology |
Daidzin (Daidzoside) 是从大豆中分离出来的一种异黄酮,具有抗氧化、抗癌和抗动脉粥样硬化的活性。 | |||
T3S0137 |
Bavachalcone
|
Antibacterial; Antibiotic | Microbiology/Virology |
Bavachalcone 是从补骨脂中分离的化合物,广泛用于中药,具有抗生素和抗癌等活性。 | |||
T3399 |
Psoralidin
|
Others; Estrogen/progestogen Receptor; Reactive Oxygen Species; Lipoxygenase; Gamma-secretase; Akt; COX; Antibacterial | Cytoskeletal Signaling; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells |
Psoralidin 是COX-2和5-LOX 的抑制剂,有抗癌,抗菌和抗炎作用。它显著下调NOTCH1信号传导,还极大地诱导活化氧产生。 | |||
T3S0136 |
4'-O-Methylbavachalcone
O-Methylbroussochalcone B,4'-O-甲基补骨脂查尔酮 |
SARS-CoV | Microbiology/Virology |
4'-O-Methylbavachalcone (O-Methylbroussochalcone B) 是从补骨脂中分离得到的一种查尔酮,可抑制严重急性呼吸综合征冠状病毒木瓜样蛋白酶的活性,IC50值为 10.1 μM。 | |||
T3823 |
D-Pinitol
Pinitol,Inzitol,D-(+)-Pinitol,D-松醇,Methylinositol,3-O-Methyl-D-chiro-inositol |
Others; Influenza Virus | Microbiology/Virology; Others |
D-Pinitol (Methylinositol) 是一种存在于几种植物中,如松科和豆科植物的天然产物,具有抗病毒、杀幼虫、降血糖活性和心血管系统保护作用。 | |||
T13354 |
Xanthoangelol
|
Apoptosis; Monoamine Transporter; Antibacterial; AMPK | Apoptosis; Chromatin/Epigenetic; Membrane transporter/Ion channel; Microbiology/Virology; PI3K/Akt/mTOR signaling |
Xanthoangelol 可从 Angelica keiskei 中提取得到,对肥胖引起的炎症反应有抑制作用。Xanthoangelol 具有抗菌活性,对单胺氧化酶有抑制作用,还诱导神经母细胞瘤和白血病细胞凋亡。 | |||
TN1148 |
Isopsoralenoside
|
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Antibacterial | Endocrinology/Hormones; Microbiology/Virology |
Isopsoralenoside 是补骨脂多糖中的一种苯并呋喃苷。它在消化道内容物中可迅速代谢为补骨脂素。它具有雌激素样活性、促进成骨细胞增殖活性、抗肿瘤活性和抗菌活性。 | |||
T8246 |
4'-METHOXYFLAVONE
|
Others | Others |
4'-METHOXYFLAVONE 是一种天然产物。 | |||
T6S0139 |
Neobavaisoflavone
|
Apoptosis; DNA/RNA Synthesis | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎,抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶,也可抑制血小板聚集。 | |||
TN1008 |
Psoralenoside
|
CaMK; Calcium Channel; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Psoralenoside 是源于补骨脂中的苯并呋喃苷,具有抗肿瘤、抗菌、促进成骨细胞增殖和雌激素样活性。它对组胺 H1、钙调素和电压门控 l 型钙通道具有较高的亲和力。 | |||
T3056 |
Bavachinin
补骨脂二氢黄酮加醚,补骨脂二氢黄酮甲醚,Bavachinin A,7-O-Methylbavachin |
PPAR | DNA Damage/DNA Repair; Metabolism |
Bavachinin (Bavachinin A) 是一种具有抗炎症和抗血管生成作用的天然化合物。 | |||
T19316 |
Ethyl oleate
|
Others | Others |
Ethyl oleate 是由油酸和乙醇的缩合形成的脂肪酸酯。它是纳米结构脂质载体 (NLC) 中的液体脂质成分。其中 NLC 是一种口服有活性的反式阿魏酸的给药载体。 | |||
TN5086 |
Syringetin
|
Others | Others |
Syringetin 是一种存在于葡萄和葡萄酒中的类黄酮衍生物,可促进 B16F10 细胞的黑色素生成,抑制人肺腺癌中成骨细胞介导的破骨细胞生成。 | |||
TN1819 |
Kaempferol 3-neohesperidoside
Kaempferol 3-O-neohesperidoside,堪非醇 3-新橙皮糖苷 |
GSK-3; MEK; PI3K | MAPK; PI3K/Akt/mTOR signaling; Stem Cells |
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) 是一种类黄酮,对大鼠比目鱼肌具有拟胰岛素作用。 | |||
T3871 |
Daucosterol
Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A,西托糖苷 |
Glucosidase | Metabolism |
Daucosterol (Sitogluside) 是天然的甾醇体类化合物。 | |||
Fr14207 |
(-)-Isopulegol
|
Others | Others |
(-)-Isopulegol 具有抗氧化和神经活性特性。它还具有由异胡薄荷醇诱导的胃保护作用,似乎至少部分由内源性前列腺素介导,K+ATP 通道开放和与 GSH 相关的抗氧化特性增加。 | |||
T6S0722 |
Isoorientin
Homoorientin,Luteolin-6-C-glucoside,异荭草苷;异荭草素,异荭草素 |
Antioxidant; COX | Immunology/Inflammation; Neuroscience; oxidation-reduction |
Isoorientin (Homoorientin) 是一种 COX-2抑制剂,IC50值为 39 μM,具有抗氧化活性。 | |||
TN2233 |
Spathulenol
|
Antioxidant; Antifungal | Microbiology/Virology; oxidation-reduction |
Spathulenol 是一种来自 Aristolochia yunnanensis 的天然成分,具有抗炎、抗氧化、抗增殖、抗溃疡和抗分枝杆菌活性。 Spathulenol 在 DPPH 系统中显示出显著的抗氧化活性,IC50 为 85.60 μg/mL。 | |||
T3697 |
3',6-Disinapoylsucrose
Disinapoyl sucrose,3,6'-Disinapoyl sucrose,3,6'-二芥子酰基蔗糖 |
BCL; Epigenetic Reader Domain | Apoptosis; Chromatin/Epigenetic |
3',6-Disinapoylsucrose (Disinapoyl sucrose) 是远志的指标成分,表现出显著的抗氧化活性和抗抑郁效果。 | |||
T6S1294 |
Nicotiflorin
Nictoflorin,Kaempferol-3-O-Rutinoside,山奈酚-3-O-芸香糖苷,Nicotifloroside |
Others | Others |
Nicotiflorin (Kaempferol-3-O-Rutinoside) 是一种黄酮苷,从传统中药Flos Carthami 中提取得到。它有抗糖化活性和神经保护作用。 | |||
T10910 |
Cycloartenol
|
Others | Others |
Cyclopentanol is a plant sterol compound and one of the key precursors for biosynthesis of various sterol compounds. Cycloartenol inhibits the migration of glioma cells and inhibits the phosphorylation of p38 MAP kinase. Cycloenol has various pharmacologi | |||
TN5445 |
Isowighteone
4',5,7-Trihydroxy-3'-prenylisoflavone |
||
Isowighteone, a compound that is not naturally produced in this species, accumulated by medicago truncatula hairy roots expressing LaPT1, indicates a strategy for metabolic engineering of novel antimicrobial compounds in legumes; it may have antimicrobial | |||
TN4086 | Furano(2'',3'',7,6)-4'-hydroxyflavanone | Others | Others |
Furano(2'',3'',7,6)-4'-hydroxyflavanone is a natural product from Psoralea corylifolia. | |||
TN3292 | 8-Prenyldaidzein | Others | Others |
8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging. | |||
TN1434 | Bavachromene | BACE | Neuroscience |
Bavachromene exhibits a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro. | |||
TN6968 |
4",5"-dehydroisopsoralidin
|
||
4",5"-dehydroisopsoralidin is a natural product. | |||
TN4840 |
Psoromic acid
|
Others | Others |
Psoromic acid is a selective and covalent rab-prenylation inhibitor targeting autoinhibited RabGGTase, it shows antibacterial activities against Streptococcus gordonii and Porphyromonas gingivalis, and it is an effective and safe natural drug plausible fo | |||
TN3711 |
Corylifol C
|
ERK; EGFR; p38 MAPK; MEK | Angiogenesis; JAK/STAT signaling; MAPK; Tyrosine Kinase/Adaptors |
Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/ml, respectively). | |||
TN2945 | 3-Hydroxybakuchiol | ATPase; Caspase | Apoptosis; Membrane transporter/Ion channel; Proteases/Proteasome |
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial perm | |||
TN4926 | Rubrosterone | Others | Others |
Rubrosterone is an insect-molting C19-steroid. | |||
T37272 |
9(S),12(S),13(S)-TriHOME
|
||
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME... | |||
TN2820 | 24-Methylenecycloartan-3-ol | Antifection | Microbiology/Virology |
24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli. |