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111

抑制剂 & 化合物

19

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T2086	ELN-441958 ELN 441958	Bradykinin Receptor	GPCR/G Protein
	ELN-441958是一种B1受体拮抗剂，能够抑制B1激动剂配体[3H] DAKD 与IMR-90细胞结合(Ki:0.26 nM)，相较于B2受体，它对B1受体的抑制作用具有更高的选择性，且比抑制μ阿片受体选择性高500多倍，比抑制δ阿片受体选择性高2000多倍。
T15430	GSK2256294A GSK 2256294	Others; Epoxide Hydrolase	Metabolism; Others
	GSK2256294A (GSK 2256294) 是重组人、大鼠和小鼠 sEH 的有效特异性抑制剂，IC50 分别为 27 pM、61 pM 和 189 pM。
T21995	XAP044	GluR	Neuroscience
	XAP044 是高效的选择性mGlu7拮抗剂。代谢型谷氨酸受体亚型 7 是哺乳动物 CNS 中神经传递的重要突触前调节剂。它在啮齿动物行为测试中表现出较好的大脑暴露、广谱抗应激、抗抑郁以及抗焦虑作用。
T1812	KX1-004 KX1 004,KX1004	Src	Angiogenesis; Tyrosine Kinase/Adaptors
	KX1-004 是非 ATP 竞争性 Src-PTK 抑制剂，IC50=40 μM。它能够保护耳蜗，使其免受有害噪音的影响，并防止噪音引起的听力损失 (NIHL)。
T20039	7-Methyladenine NSC7857,7-甲基腺嘌呤,NSC-7857,NSC 7857	Others	Others
	7-Methyladenine (NSC-7857) 可用作暴露于外源性和致癌性甲基化剂的标志物。
T8547	DCBA	Drug Metabolite	Metabolism
	DCBA 是驱虫剂 N-N-diethyl-meta-toluamide (DEET) 的代谢物。尿液中 DCBA 的浓度是评估 DEET 暴露程度的指标。
TQ0039	(±)-Zanubrutinib (±)-BGB-3111	BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	(±)-Zanubrutinib ((±)-BGB-3111) 是一种有效的口服Bruton’s 酪氨酸激酶(Btk)抑制剂，具有优越的口服生物利用度，可实现更高的暴露量和更完整的靶点抑制。
T36478	BI-6901	CCR	Immunology/Inflammation; Microbiology/Virology
	BI-6901 是一种选择性 CCR10 拮抗剂。在DNFB接触超敏反应的小鼠模型中，BI 6901 以剂量依赖的方式显示其抗炎反应。
T0976	Propoxur 残杀威,Aprocarb,Propoxure,Baygon	AChR; Antifungal	Microbiology/Virology; Neuroscience
	Propoxur (Propoxure) 是一种氨基甲酸酯类杀虫剂，用于控制蟑螂、苍蝇、蚊子以及草坪和草坪昆虫。
T35501	5,6-trans-Vitamin D3 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A	Vitamin	Metabolism
	5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol）是维生素 D3 的异构体，经光照后在皮肤表面由 Vitamin D3 转化而来。
T3106	C-DIM12	Apoptosis; Others	Apoptosis; Others
	C-DIM12是一种人工合成的Nurr1激活剂，可诱导Nurr1和DA 基因表达。
T17315	(±)-CPSI-1306 cpsi-1306,2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one	Others	Others
	(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) 是一种巨噬细胞迁移抑制因子 (MIF) 拮抗剂，可用于关于非胰岛素依赖型糖尿病 (NIDDM) 的研究以及预防急性和慢性 UVB 暴露对皮肤的有害影响。
T21404	Fluticasone furoate Veramyst,Allermist,Avamys,糠酸氟替卡松,Fluticasone furoate	Glucocorticoid Receptor	Endocrinology/Hormones
	Fluticasone furoate (Avamys) 是一种合成的三氟化皮质类固醇，衍生自氟替卡松，Kd 为 0.3 nM。Fluticasone furoate 具有有效的抗炎、抗哮喘活性和低全身暴露。Fluticasone furoate 可用作过敏性鼻炎治疗研究的鼻喷雾剂。
T22341	GSK-114	Others	Others
	GSK 114 是口服有活性的、高选择性的TNNI3K 抑制剂 (IC50= 25 nM)。其中TNNI3K (又称 CARK) 是酪氨酸样激酶家族的成员，选择性在心脏组织中表达。它对 TNNI3K 的选择性是 B-Raf 激酶的 40 倍 (IC50= 1 µM)。
T0357	Potassium iodide	Tyrosinase	Proteases/Proteasome
	Potassium iodide 用于治疗过度活跃的甲状腺，并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。
T37547	trans-Urocanic Acid
	trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes to the acidification of the surface of the stratum corneum, and its function has been proposed as that of an endogenous sunscreen, endowing a low-level of protection (SPF ~ 1.5) against UV-induced DNA damage and excessive keratinocyte apoptosis. Upon UVB exposure, trans-urocanic ...
T1435	Praziquantel 吡喹酮,Pyquiton,Droncit,Biltricide	Calcium Channel; Antibiotic; Parasite	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Praziquantel (Droncit) 是一种外消旋混合物，由 (R)-Praziquantel 和 (S)-Praziquantel 组成。它可研究血吸虫病。
TP1179L	Porcine dynorphin A(1-13) acetate Dynorphin A Porcine Fragment 1-13 acetate,Porcine dynorphin A(1-13) acetate(72957-38-1 free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Porcine dynorphin A(1-13) acetate (Dynorphin A Porcine Fragment 1-13 acetate)(72957-38-1 free base) 是一种有效的内源性 κ opioid 受体激动剂，在生理浓度下具有镇痛作用。暴露于强啡肽 A (1-13) 会导致单个神经元中 [Ca2+]i 的急剧增加，类似于急性 NMDA 治疗所见的增加。
T1787	Levobupivacaine	Sodium Channel	Membrane transporter/Ion channel
	Levobupivacaine 是一种氨基酰胺类局麻药，属于n-alkylsubstituted pipecoloxylidide 家族。它是bupivacaine 的 S-对映异构体。
T38003	Levofloxacin N-oxide	Others	Others
	Levofloxacin N-oxide 是从左氧氟沙星中分离出来的杂质。
T36141	Boscalid	Mitochondrial Metabolism	Metabolism
	Boscalid 是一种广谱羧酰胺类杀菌剂，通过与线粒体复合物 II/琥珀酸脱氢酶的泛醌位点结合来抑制真菌呼吸。
T8675	Vaniprevir	Others	Others
	Vaniprevir is a macrocyclic hepatitis C virus NS3/4a protease inhibitor and is active against both the genotype 1 and genotype 2 NS3/4a protease enzymes. vaniprevir has good plasma exposure and excellent liver exposure in multiple species.
T39136	ATX inhibitor 7
	ATX inhibitor 7 is a autotaxin inhibitor and shows good oral exposure.
T34777	Talaporfin free acid Monoaspartyl chlorin,NPe6,Talaporfin,Aspartyl chlorin
	Talaporfin, an effective tumor localizer, can produce the selective degradation of tumor tissue following light exposure.
T71091	Y2-Antagonist-2
	Y2-Antagonist-2 is a novel, selective, soluble non-peptidic NPY Y2 receptor antagonist with enhanced CNS exposure.
T26525	ABT-281 ABT 281,A-86281,A 86281,ABT281,A86281
	ABT-281 is an ascomycin analog and a macrolactam T cell inhibitors with potent topical activity and reduced systemic exposure.
T29689	AFB1-N7-guanine
	In epidemiological studies, Aflatoxin B1-N7-guanine serum albumin adducts have been established as biomarkers of dietary aflatoxin exposure.
T68335	MK-1220
	MK-1220 is a novel Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure.
T70223	UA8967
	UA8967 is a membrane-active anti-tumor agent. Cytotoxicity studies in six pancreatic cancer cell lines, one normal human pancreatic ductal epithelial line and two colon cancer cells showed the IC50s UA8967 ranged from 12–61 μM for exposure times of 72 h. There was also no selective inhibition of DNA, RNA or protein synthesis after exposure to UA8967. UA8967 is observed to affect the plasma membrane.
T14879	CB 300919	Others	Others
	CB 300919 is a quinazoline-based antitumor agent with high activity in the CH1 human ovarian tumor xenograft and has continuous exposure (96 h) growth inhibition (IC50: 2 nM).
T16372	Obidoxime dichloride	Others	Others
	Obidoxime dichloride, a selective oxime agent, effectively reactivates sarin-inhibited acetylcholinesterase (AChE) and mitigates the acute toxicity associated with sarin exposure. It is also utilized as an antidote for organophosphate nerve agent poisoning.
T6060L	Anabasine HCl BB-NC-0036,CCG-38440,H-8174,AR-1H7273,ZX-BK000320,ST-24041653
	Anabasine HCl is used as a clinical biomarker for tobacco smoke exposure and as an insecticide. It is also a depolarizing NMJ blocker, aromatase inhibitor, nAChr antagonist, and teratogen found in species of Nicotiana.
T69607	Dersimelagon phosphate
	Dersimelagon phosphate is a selective melanocortin-1 receptor (MC1R) agonist that increases skin melanin without sun exposure and is being developed to increase light tolerance in EPP/XLP patients.
T30691	Calcium diglutamate Calcium di-L-glutamate,Glutamic acid, calcium salt (2:1), L-
	Calcium diglutamate(CDG), calcium acid salt of glutamic acid. As a soluble source of calcium ions, this chemical is used as a first-aid treatment for exposure to hydrofluoric acid.
T61174	MT-134
	MT-134 是一种 SkMII 特异性抑制剂，在肌肉中具有良好的暴露性。
T14570	BI 99179 BI99179	Fatty Acid Synthase	Metabolism
	BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1].
T70608	cis-Entacapone
	cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone. It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.
T35236	5α-Hydroxy-6-keto cholesterol YS 64,Yakkasterone,5α-羟基-6-酮胆固醇
	Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.
T31194	Dalapon Basfapon B,Dowpon M,Dawpon-Rae
	Dalapon is a selective herbicide used to control perennial grasses. The major use of dalapon is on food crops including sugarcane and sugar beets. Its use is no longer authorized in France. The National Institute for Occupational Safety and Health in the
T35458	(R)-nitro-Blebbistatin
	(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin , which is the inactive form of (-)-blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereoche...
T26573	AG311 AG 311,AG-311
	AG311 is an inhibitor of complex I and hypoxia-induced HIF-1α stabilization. In vitro, AG311 induces rapid necrosis in numerous cancer cell lines. Within minutes, exposure to AG311 also results in mitochondrial depolarization, superoxide production, and i
T40226	FP-Biotin
	FP-biotin is a potent organophosphorus toxicant, ideal for identifying novel biomarkers of organophosphorus toxicant exposure. It measures FAAH, ABHD6, and MAG-lipase activity, specifically in plasma studies, due to the efficient purification of biotinylated peptides through binding to immobilized avidin beads.
T40397	3,4,6-Trichlorocatechol
	3,4,6-Trichlorocatechol (TCC) is a metabolite generated by the post-mitochondrial liver fraction in Aroclor-1254 induced rats, resulting from exposure to industrial pollutants.
T37704	Olanzapine Lactam Impurity
	Olanzapine lactam impurity is a potential impurity found in commercial preparations of olanzapine.1It is a degradation product formed by exposure to thermal or oxidative stress. 1.Baertschi, S.W., Brunner, H., Bunnell, C.A., et al.Isolation, identification, and synthesis of two oxidative degradation products of olanzapine (LY170053) in solid oral formulationsJ. Pharm. Sci.97(2)883-892(2008)
T38267	Valeryl-L-carnitine (chloride) Valeryl-L-carnitine (chloride),L-Valerylcarnitine
	Valeryl-L-carnitine is a short-chain acylcarnitine and a derivative of L-carnitine . Valeryl-L-carnitine levels increase in the serum of rhesus monkeys following exposure to 7 and 10 Gray units (Gy) of ionizing radiation.[1]
T26821	BIPM
	BIPM is a potent inhibitor of Rho-associated protein kinase 2 (ROCK2). Exposure of SH-SY5Y cells to BIPM led to significant changes in cell migration, actin stress fibers and neurite length. BIPM significantly inhibits phosphorylation of cofilin, a regula
T61528	FGFR-IN-7
	FGFR-IN-7 (compound 17) is an orally active, potent FGFR modulator with the ability to penetrate the blood-brain barrier. It exhibits neuroprotective properties, enhancing brain exposure and decreasing the likelihood of phospholidosis. FGFR-IN-7 proves valuable for research on neurodegenerative diseases [1].
T11986	Mebeverine acid Mebeverine metabolite Mebeverine acid,美贝维林酸	Drug Metabolite	Metabolism
	Mebeverine acid (Mebeverine metabolite Mebeverine acid) 是美贝维林的次级代谢产物，可用作口服美贝维林的标志物。
TP1179	Porcine dynorphin A(1-13) Dynorphin A Porcine Fragment 1-13
	Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acut
T14682	BMS-962212	Others	Others
	BMS-962212, a direct, reversible, and selective factor XIa (FXIa) inhibitor, demonstrates fast pharmacodynamic (PD) response onset and rapid elimination with a well-tolerated profile. It dependently increases activated partial thromboplastin time and decreases FXI clotting activity exposure [1].

化合物

Cat.No: T2086

Synonym: ELN 441958

Target: Bradykinin Receptor

Cat.No: T15430

Synonym: GSK 2256294

Target: Others, Epoxide Hydrolase

Cat.No: T21995

Target: GluR

Cat.No: T1812

Synonym: KX1 004,KX1004

Target: Src

7-Methyladenine

Cat.No: T20039

Synonym: NSC7857,7-甲基腺嘌呤,NSC-7857,NSC 7857

Target: Others

Cat.No: T8547

Target: Drug Metabolite

(±)-Zanubrutinib

Cat.No: TQ0039

Synonym: (±)-BGB-3111

Target: BTK

Cat.No: T36478

Target: CCR

Cat.No: T0976

Synonym: 残杀威,Aprocarb,Propoxure,Baygon

Target: AChR, Antifungal

5,6-trans-Vitamin D3

Cat.No: T35501

Synonym: 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A

Target: Vitamin

Cat.No: T3106

Target: Apoptosis, Others

Cat.No: T17315

Synonym: cpsi-1306,2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one

Target: Others

Fluticasone furoate

Cat.No: T21404

Synonym: Veramyst,Allermist,Avamys,糠酸氟替卡松,Fluticasone furoate

Target: Glucocorticoid Receptor

Cat.No: T22341

Target: Others

Potassium iodide

Cat.No: T0357

Target: Tyrosinase

trans-Urocanic Acid

Cat.No: T37547

Cat.No: T1435

Synonym: 吡喹酮,Pyquiton,Droncit,Biltricide

Target: Calcium Channel, Antibiotic, Parasite

Porcine dynorphin A(1-13) acetate

Cat.No: TP1179L

Synonym: Dynorphin A Porcine Fragment 1-13 acetate,Porcine dynorphin A(1-13) acetate(72957-38-1 free base)

Target: Opioid Receptor

Levobupivacaine

Cat.No: T1787

Target: Sodium Channel

Levofloxacin N-oxide

Cat.No: T38003

Target: Others

Cat.No: T36141

Target: Mitochondrial Metabolism

Cat.No: T8675

Target: Others

ATX inhibitor 7

Cat.No: T39136

Talaporfin free acid

Cat.No: T34777

Synonym: Monoaspartyl chlorin,NPe6,Talaporfin,Aspartyl chlorin

Y2-Antagonist-2

Cat.No: T71091

Cat.No: T26525

Synonym: ABT 281,A-86281,A 86281,ABT281,A86281

AFB1-N7-guanine

Cat.No: T29689

Cat.No: T68335

Cat.No: T70223

Cat.No: T14879

Target: Others

Obidoxime dichloride

Cat.No: T16372

Target: Others

Cat.No: T6060L

Synonym: BB-NC-0036,CCG-38440,H-8174,AR-1H7273,ZX-BK000320,ST-24041653

Dersimelagon phosphate

Cat.No: T69607

Calcium diglutamate

Cat.No: T30691

Synonym: Calcium di-L-glutamate,Glutamic acid, calcium salt (2:1), L-

Cat.No: T61174

Cat.No: T14570

Synonym: BI99179

Target: Fatty Acid Synthase

Cat.No: T70608

5α-Hydroxy-6-keto cholesterol

Cat.No: T35236

Synonym: YS 64,Yakkasterone,5α-羟基-6-酮胆固醇

Cat.No: T31194

Synonym: Basfapon B,Dowpon M,Dawpon-Rae

(R)-nitro-Blebbistatin

Cat.No: T35458

Cat.No: T26573

Synonym: AG 311,AG-311

Cat.No: T40226

3,4,6-Trichlorocatechol

Cat.No: T40397

Olanzapine Lactam Impurity

Cat.No: T37704

Valeryl-L-carnitine (chloride)

Cat.No: T38267

Synonym: Valeryl-L-carnitine (chloride),L-Valerylcarnitine

Cat.No: T26821

Cat.No: T61528

Mebeverine acid

Cat.No: T11986

Synonym: Mebeverine metabolite Mebeverine acid,美贝维林酸

Target: Drug Metabolite

Porcine dynorphin A(1-13)

Cat.No: TP1179

Synonym: Dynorphin A Porcine Fragment 1-13

Cat.No: T14682

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN7118	Methylhippuric acid Methyl hippurate,N-苯甲酰基甘氨酸甲酯
	Methylhippuric acid (Methyl hippurate) 是人体尿液中二甲苯暴露的生物标志物。
T4931	Dihydroxyfumaric acid hydrate	Others; Endogenous Metabolite	Metabolism; Others
	Dihydroxyfumaric acid hydrate 是内源性代谢产物的一种。
T5S1550	Cinnamyl alcohol 肉桂醇,肉桂醇；beta-苯丙烯醇,Cinnamic Alcohol,Styryl Carbinol	PPAR	DNA Damage/DNA Repair; Metabolism
	Cinnamyl alcohol (Styryl Carbinol) 是从板栗花中分离得到的一种活性成分，抑制增加的 PPARγ表达，具有抗肥胖作用。
T19082	1-Hydroxypyrene 1-Pyrenol,Pyren-1-ol,1-羟基芘	Endogenous Metabolite	Metabolism
	1-Hydroxypyrene (1-Pyrenol) 是一种暴露于多环芳烃的生物标志物，存在尿液样本中，也是一种暴露于 pyrenes 中的主要生物标志物。
T5718	L-(+)-Abrine L-(+)-红豆碱,L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE	Others	Others
	L-(+)-Abrine (L-N-Methyltryptophan) 是一种致命白蛋白，发现于在 Abrus precatorius 种子中，是一种急性毒性生物碱，可用作化学标记物。
T3746	Dimethyl phthalate 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯	Others	Others
	Dimethyl phthalate (Fermine) 是一种邻苯二甲酸酯 (PAEs)，是一种已知的内分泌干扰物，也是一种普遍存在的污染物。它常作为增塑剂，赋予硬质聚氯乙烯 (PVC) 树脂以柔韧性。
T4787	2-Hydroxyisobutyric acid 2-甲基-2-羟基丙酸,α-Hydroxyisobutyric acid	Others; Endogenous Metabolite	Metabolism; Others
	2-Hydroxyisobutyric acid (α-Hydroxyisobutyric acid) 是内源性代谢产物的一种。
T1659	Melatonin Melatonine,松果体素,N-Acetyl-5-methoxytryptamine,褪黑素	CaMK; Apoptosis; Mitophagy; Estrogen/progestogen Receptor; Melatonin Receptor; Glutathione Peroxidase; Endogenous Metabolite; ROR; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience
	Melatonin (Melatonine) 是一种由松果体制成的激素，可激活褪黑激素受体。它在睡眠中起作用，有抗氧化和抗炎特性。它是新型选择性ATF-6抑制剂，可诱导细胞凋亡。
T2S0633	Raspberry ketone Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone,覆盆子酮	PPAR	DNA Damage/DNA Repair; Metabolism
	Raspberry ketone (p-Hydroxybenzyl acetone) 是覆盆子中主要的芳香族天然产物，主要用作化妆品的香料和食品增味剂，也可作 PPAR-α激动剂。
T5S0018	Betulonic acid 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid	Parasite; HSV	Microbiology/Virology
	Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物，具有抗肿瘤，抗炎，抗寄生虫和抗病毒的活性。
T6S1917	Schisandrol B Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B	P450; Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Schisandrol B (Besigomsin) 是华中五味子的主要活性成分，具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生，也抑制 P-糖蛋白和CYP3A 的活性。
T3S0013	Ethyl trans-caffeate 咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester	Others	Others
	Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) 具有抗炎作用。它是一种有前途的天然化合物，未来在慢性肝病中的应用。它是一种有效的化学预防化合物，可防止因太阳紫外线照射引起的皮肤癌变。它是与人胰腺α-淀粉酶复合的代表性抑制剂的高分辨率结构。它强烈抑制 JB6 Cl41细胞的肿瘤转化，无毒性。 PI3K、ERK1/2 和 p38 激酶活性在体外通过与 HOEC 直接结合而受到抑制。
T37280	PE(18:1(9Z)/0:0)	Endogenous Metabolite	Metabolism
	PE(18:1(9Z)/0:0) 是一种天然存在的溶血磷脂，是缩醛磷脂溶血磷脂酰乙醇胺的类似物。 PE(18:1(9Z)/0:0) 以浓度依赖性方式诱导 PC12 大鼠神经元细胞中细胞内钙的瞬时增加。 PE(18:1(9Z)/0:0) 增加 IL-4 和 IL-2 的产生，但不增加 IFN-γ 的产生。在小鼠血清中，PE(18:1(9Z)/0:0)（1 μg/动物）诱导 T 辅助细胞 2 反应。在寒冷暴露三天后，小鼠肩胛间棕色脂肪组织中的 PE(18:1(9Z)/0:0) 水平增加。
T39836	Monoethyl phthalate
	Monoethyl phthalate is a metabolite of diethyl phthalate, serving as a urinary biomarker for phthalate exposure, and indicating potential risks of thyroid cancer and benign nodules.
TN4026	Eucamalol	Others	Others
	Eucamolol exhibits significant repellent activity against Aedes albopictus, and inhibits its feeding as well as DEET, is effective repellent (75%) up to 3 h after exposure to mosquito.
TN1766	(-)-Integerrimine Integerrimine,全緣千里光鹼,全缘千里光碱	Others	Others
	Prenatal exposure to Integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delayed in physical and behavioral development of the offspring. Doses of Integerrimine N-oxide here employed did not produce marked immunotoxic effects.
T83108	Anhuienoside B
	Anhuienoside B为从C. anhuiensis K. F. Wu鲜叶中提取的天然产物，能应对CuCl2诱导的非生物胁迫。
T40859	5-Hydroxy-8-methoxypsoralen 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen
	5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite derived from Xanthotoxin, which acts as a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). It is employed as an agent for the treatment of psoriasis, eczema, vitiligo, and certain cutaneous Lymphomas, in combination with phototherapy involving exposure to sunlight.
T80950	Tricetin 7-O-glucoside
	Tricetin 7-O-glucoside (compound 33)为一种黄酮类单-O-糖苷。

天然产物

Methylhippuric acid

Cat.No: TN7118

Synonym: Methyl hippurate,N-苯甲酰基甘氨酸甲酯

Dihydroxyfumaric acid hydrate

Cat.No: T4931

Target: Others, Endogenous Metabolite

Cinnamyl alcohol

Cat.No: T5S1550

Synonym: 肉桂醇,肉桂醇；beta-苯丙烯醇,Cinnamic Alcohol,Styryl Carbinol

Target: PPAR

1-Hydroxypyrene

Cat.No: T19082

Synonym: 1-Pyrenol,Pyren-1-ol,1-羟基芘

Target: Endogenous Metabolite

Cat.No: T5718

Synonym: L-(+)-红豆碱,L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE

Target: Others

Dimethyl phthalate

Cat.No: T3746

Synonym: 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯

Target: Others

2-Hydroxyisobutyric acid

Cat.No: T4787

Synonym: 2-甲基-2-羟基丙酸,α-Hydroxyisobutyric acid

Target: Others, Endogenous Metabolite

Cat.No: T1659

Synonym: Melatonine,松果体素,N-Acetyl-5-methoxytryptamine,褪黑素

Target: CaMK, Apoptosis, Mitophagy, Estrogen/progestogen Receptor, Melatonin Receptor, Glutathione Peroxidase, Endogenous Metabolite, ROR, Autophagy

Raspberry ketone

Cat.No: T2S0633

Synonym: Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone,覆盆子酮

Target: PPAR

Cat.No: T5S0018

Synonym: 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid

Target: Parasite, HSV

Cat.No: T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Ethyl trans-caffeate

Cat.No: T3S0013

Synonym: 咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester

Target: Others

PE(18:1(9Z)/0:0)

Cat.No: T37280

Target: Endogenous Metabolite

Monoethyl phthalate

Cat.No: T39836

Cat.No: TN4026

Target: Others

(-)-Integerrimine

Cat.No: TN1766

Synonym: Integerrimine,全緣千里光鹼,全缘千里光碱

Target: Others

Cat.No: T83108

5-Hydroxy-8-methoxypsoralen

Cat.No: T40859

Synonym: 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen

Tricetin 7-O-glucoside

Cat.No: T80950

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