Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2-Hydroxyisobutyric acid (α-Hydroxyisobutyric acid) 是内源性代谢产物的一种。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 mg | ¥ 289 | 现货 | ||
100 mg | ¥ 413 | 现货 | ||
200 mg | ¥ 588 | 现货 | ||
500 mg | ¥ 980 | 现货 |
产品描述 | 2-Hydroxyisobutyric acid (α-Hydroxyisobutyric acid) is a metabolite of methyl tert-butyl ether (MTBE). MTBE may be obtained through environmental exposure. MTBE is rapidly eliminated from the body, mainly through expired air as the unchanged compound. MTBE is to some extent metabolised to t-butyl alcohol (TBA) and formaldehyde and oxidised to 2-methyl-1,2-propanediol and a-hydroxy isobuturic acid. 2-Hydroxyisobutyric acid has been used as an arial bactericide. |
体内活性 | Glycerol can induce acute renal failure in rat models. Acute renal failure induced by glycerol or uranyl nitrate reduces the hepato-biliary transport of some drugs, modulates the distribution of drugs into the central nervous system and affects the activity of various hepatic microsomal enzymes. |
别名 | 2-甲基-2-羟基丙酸, α-Hydroxyisobutyric acid |
分子量 | 104.1 |
分子式 | C4H8O3 |
CAS No. | 594-61-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 200 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 9.6061 mL | 48.0307 mL | 96.0615 mL | 240.1537 mL |
5 mM | 1.9212 mL | 9.6061 mL | 19.2123 mL | 48.0307 mL | |
10 mM | 0.9606 mL | 4.8031 mL | 9.6061 mL | 24.0154 mL | |
20 mM | 0.4803 mL | 2.4015 mL | 4.8031 mL | 12.0077 mL | |
50 mM | 0.1921 mL | 0.9606 mL | 1.9212 mL | 4.8031 mL | |
100 mM | 0.0961 mL | 0.4803 mL | 0.9606 mL | 2.4015 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
2-Hydroxyisobutyric acid 594-61-6 Metabolism Others Endogenous Metabolite Inhibitor 2-甲基-2-羟基丙酸 a-Hydroxyisobutyric acid inhibit 2 Hydroxyisobutyric acid alpha-Hydroxyisobutyric acid 2Hydroxyisobutyric acid α-Hydroxyisobutyric acid inhibitor