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52

抑制剂 & 化合物

9

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8239	Cromoglicic acid	Others	Others
	Cromoglicic acid 可防止肥大细胞释放炎性化学物质，例如组胺。
T9350	IMP-1088	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	IMP-1088 是一种人N-肉豆蔻酰基转移酶NMT1和NMT2双重抑制剂，对 HsNMT1 和 HsNMT2 的IC50小于1 nM，对 HsNMT1 的Kd 小于210 pM。它有保护宿主细胞免受病毒感染的细胞毒作用，通过阻断鼻病毒的 N-肉豆蔻酰化蛋白来阻断鼻病毒的复制。
T3965	Fevipiprant QAW039,NVP-QAW039,非维匹仑	GPR; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
	Fevipiprant (NVP-QAW039) 是一种选择性、强效、可逆的竞争性 CRTh2 拮抗剂，KD 值为1.1 nM，IC50为0.44 nM，能够引发人体嗜酸性粒细胞的形状变化。
T0188	Fluticasone (propionate) 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate	Glucocorticoid Receptor; Virus Protease; Estrogen/progestogen Receptor; Phospholipase; Endogenous Metabolite	Endocrinology/Hormones; Metabolism; Microbiology/Virology
	Fluticasone propionate (CCI-187881) 是一种选择性糖皮质激素受体激动剂，是一种局部抗炎激素，亲和力KD 为 0.5 nM。具有抗病毒活性。
T5872	Faltan 灭菌丹,Folpet	Antifungal	Microbiology/Virology
	Faltan (Folpet) 是一种广泛使用的二甲酰亚胺类杀菌剂，可诱发小鼠胃肠道肿瘤，主要发生在十二指肠，对人支气管上皮细胞也有细胞毒作用。
T0277	Metaproterenol hemisulfate Orciprenaline sulfate,Metaproterenol Sulfate,硫酸奥西那林	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Metaproterenol hemisulfate (Orciprenaline sulfate) 是一种 β2-肾上腺素能受体 (β2AR) 激动剂(IC50=68 nM)，是一种直接作用的拟交感神经药，具有抗炎活性。
T2270	Trans-Tranilast Tranilast trans-,反式-曲尼司特,反-曲尼司特	RAAS	Endocrinology/Hormones
	Trans-Tranilast 是抗过敏剂，可用于过敏性鼻炎、支气管哮喘和特应性皮炎的研究。
T0477	Zileuton Abbott 64077,齐留通,A 64077	Ferroptosis; Lipoxygenase; COX	Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience
	Zileuton (A 64077) 是羟基脲的合成衍生物，是一种选择性的5-脂氧合酶抑制剂，具有平喘特性。
T3126	Bethanechol chloride (±)-Bethanechol,Urecholine,Myocholine,氯贝胆碱,Carbamyl-β-methylcholine chloride	AChR	Neuroscience
	Bethanechol chloride (Carbamyl-β-methylcholine chloride) 是一种拟副交感神经剂，是毒蕈碱型受体 (mAChR) 激动剂，通过直接刺激副交感神经系统的 mAChR 发挥作用。
T4195	Betahistine PT 9 base,倍他司汀,Vasomotal,Serc base	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Betahistine (Vasomotal) 是可口服的组胺 H1 受体激动剂和 H3 受体的拮抗剂，可用作血管扩张剂，用于类风湿性关节炎的研究。
T0098	Ipratropium bromide monohydrate Ipratropium bromide hydrate,溴化异丙托品单水合物	AChR	Neuroscience
	Ipratropium bromide monohydrate (Ipratropium bromide hydrate) 是一种毒蕈碱拮抗剂，结构上与阿托品相关，但它通常被认为对吸入使用更安全、更有效。它用于各种支气管疾病、鼻炎和抗心律失常。
T60522	Letosteine Viscotiol	Others	Others
	Letosteine (Viscotiol) 是具有口服活性、有效且安全的祛痰剂，可用于研究急性或慢性呼吸道疾病，如支气管肺炎。Letosteine 能够溶解支气管粘液并减轻呼吸道炎症症状，从而实现恢复肺部气体交换和自然防御机制。
T1115	Doxylamine succinate 琥珀酸多西拉敏,Decapryn	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Doxylamine succinate (Decapryn) 是一种吡啶衍生物组胺 H1 拮抗剂，具有明显的镇静特性。它竞争性阻断组胺 H1 受体并限制典型的过敏和过敏反应，可防止组胺引起的皮肤和粘膜疼痛和瘙痒。
T1012	Acebutolol hydrochloride 盐酸醋丁洛尔,Acebutolol HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Acebutolol hydrochloride (Acebutolol HCl) 是一种 β-肾上腺素受体拮抗剂，用于研究高血压、心绞痛和心律失常。
T1006	Propantheline bromide Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl	AChR	Neuroscience
	Propantheline bromide (Pro-Banthine) 是一种抗毒蕈碱剂，用于研究多汗症，遗尿，胃肠和膀胱痉挛。
T1682	Methacholine Chloride 醋甲胆碱,Mecholyl chloride,氯化乙酰甲胆碱,Acetyl-β-methylcholine chloride	AChR	Neuroscience
	Methacholine Chloride (Acetyl-β-methylcholine chloride) 是副交感神经系统中的毒蕈碱-3 受体激动剂。它可用于测量气道高反应性，作为评估哮喘样症状和正常静息呼气流速的诊断辅助手段。它直接作用于平滑肌上的乙酰胆碱受体，引起收缩和气道狭窄。
T1139	Salbutamol Albuterol,沙丁胺醇,AH-3365	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Salbutamol (Albuterol) 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病(COPD) 引发的支气管痉挛的研究。
T1083L	Theophylline monohydrate Quibron,茶碱一水合物	HDAC; PDE; Adenosine Receptor	Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Theophylline monohydrate (Quibron) 似乎抑制磷酸二酯酶和前列腺素的产生，调节钙通量和细胞内钙分布，并拮抗腺苷。茶碱是黄嘌呤的天然生物碱衍生物，从植物山茶花和小粒咖啡中分离出来。在生理上，该药剂可放松支气管平滑肌，产生血管舒张（脑血管除外），刺激中枢神经系统，刺激心肌，利尿，增加胃酸分泌；它还可以抑制炎症并改善横膈膜的收缩性。
T38063	N-Acetyl lysyltyrosylcysteine amide	Glutathione Peroxidase	Metabolism
	N-Acetyl lysyltyrosylcysteine amide 是一种无毒的髓过氧化物酶 (MPO) 三肽抑制剂，具有有效性，可逆性和特异性。N-Acetyl lysyltyrosylcysteine amide 在体内可有效抑制 MPO 产生。N-Acetyl lysyltyrosylcysteine amide 减轻中风后大脑的神经元损伤，并保留脑组织和神经功能。N-Acetyl lysyltyrosylcysteine amide 抑制MPO依赖性次氯酸 (HOCl) 的生成，蛋白质硝化和 LDL 氧化。N-Acetyl lysyltyrosylcysteine amide 可用于研究支气管发育不良。
T0920	Ambroxol 氨溴索,氨溴索碱,Ambroxolum,NA-872	P450; Autophagy	Autophagy; Metabolism
	Ambroxol (NA-872) 是前药溴己辛的活性代谢产物，是一种分泌溶解剂，具有强效祛痰作用，用于治疗与粘液或过多粘液相关的呼吸道疾病。它可诱导肺组织细胞自噬，有用于帕金森氏病和神经性戈谢病的研究潜力。它是一种葡糖脑苷脂酶伴侣，可增加葡糖脑苷脂酶的活性。
T36466	Chlorin E6 Ce6,Chlorin e6,CE6	Parasite	Microbiology/Virology
	Chlorin E6 (CE6) 是一种第二代光敏剂，在与辐照结合使用时具有抗肿瘤活性。在植入性纤维肉瘤的小鼠模型中，Chlorin E6（2.5-10 毫克/千克，静脉注射，50-200 焦耳/平方厘米的辐照）在不同程度的辐照后会导致肿瘤完全消失。在一项针对支气管源性早期浅表鳞状细胞癌患者的 I 期临床研究中，对包括 Chlorin E6 在内的制剂进行了测试，结果良好（40 毫克/平方米，静脉注射，100 焦耳/平方厘米的激光辐照）。在一项针对早期肺癌患者的二期临床试验中，同样的给药模式使 82.9% 的患者获得了完全应答。Chlorin E6 已被研究为一种纳米技术给药工具。
T28651	S-5751 S 5751
	S-5751, a prostanoid DP (DP1) antagonist, is used potentially for the treatment of bronchial asthma.
T30141L	Arpenal HCl Arpenal hydrochloride
	Arpenal HCl is a ganglionic blocking agent which may be useful in the treatment of bronchial asthma.
T30141	Arpenal
	Arpenal is a ganglionic blocking agent which may be useful in the treatment of bronchial asthma.
T23472	Tranilast Sodium	Others	Others
	Tranilast Sodium has been used for the treatment of bronchial asthma. Tranilast is also used to autoimmune diseases, atopic and fibrotic pat.
T30827	Cgp 33304 Cgp-33304,Cgp33304
	CGP 33304 is a dual leukotriene receptor antagonist and phospholipase A2 inhibitor. It prevents hypoxia secondary to bronchial constriction induced by leukotriene in a shocking state.
T30835	Cgp 45715A Cgp45715A,Cgp-45715A
	CGP 45715A (irukostat) is a potent peptide-leukotriene antagonist used to treat respiratory diseases by antagonizing the bronchial constriction, mucus secretion, and inflammatory effects of these leukotrienes.
T70294	KAA-276 free base
	KAA-276 free base is a novel potent and long-lasting histamine HI-receptor antagonist with less-topical irritation, and can be topically administered by inhalation for the treatment of bronchial asthma.
T35883	RNF5 inhibitor inh-02 RNF5 inhibitor inh-02
	RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation. This compound is valuable for cystic fibrosis research[1].
T61702	SRI-37240
	SRI-37240 is a powerful inhibitor of premature termination codons (PTCs). It effectively suppresses CFTR nonsense mutations and induces changes in cellular translation termination at PTCs in HEK293T cells. Additionally, when combined with G418, SRI-37240 restores CFTR function in primary bronchial epithelial cells [1].
T70293	KAA-276 HCl
	KAA-276 HCl is the salt form of KAA-276 free base, a novel potent and long-lasting histamine HI-receptor antagonist with less-topical irritation, and can be topically administered by inhalation for the treatment of bronchial asthma.
T61075	Piperilate
	Piperilate, also known as Pipethanate, is a hetrazepine derivative PAF antagonist and anticholinergic mixture, commonly utilized in bronchial asthma research. This compound exhibits hypotensive properties and has been found to effectively counteract the toxic effects of organophosphates in mice [1] [2] [3].
T21020	Antazoline phosphate
	Antazoline phosphate is an antihistamine with anticholinergic properties. Antazoline prevents the typical allergic symptoms on capillaries, mucous membranes, skin, and gastrointestinal and bronchial smooth muscles by antagonizing the histamine H1 receptor
T69025	Ipratropium Free Base
	Ipratropium Free Base is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
T21411	Isoproterenol Norisodrine,Isoprenaline,Novodrin,Isuprel,Medihaler-Iso	Endogenous Metabolite; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Isoproterenol (Norisodrine) 是一种非选择性且具有口服活性的 β-肾上腺素受体激动剂。Isoproterenol 是有效的外周血管扩张剂和支气管扩张剂。Isoproterenol 可用于研究心动过缓和支气管哮喘，用于治疗心脏传导阻滞、心动过缓。
T121458	8011-6561
	1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol 是一种抗胆碱能药物，具有用于支气管哮喘研究的潜力。
T26628	Andolast CR2039,CR-2039,CR 2039
	Andolast, also known as CR-2039, an anti-allergic agent for the treatment of bronchial asthma, chronic obstructive pulmonary disease (COPD). Andolast acts at different cellular levels to inhibit immunoglobulin E synthesis. Andolast proved to be significan
T61306	SRI-41315
	SRI-41315, a chemical compound, effectively addresses premature termination codons (PTCs) associated with cystic fibrosis in immortalized and primary human bronchial epithelial cells. It induces a prolonged pause at stop codons, resulting in the restoration of cystic fibrosis transmembrane conductance regulator (CFTR) expression and function. This compound achieves PTC suppression by reducing the abundance of the termination factor eRF1. Additionally, SRI-41315 synergistically enhances CFTR acti...
T60590	Chloropyramine
	Chloropyramine 是竞争性可逆 H1 受体拮抗剂，可用于过敏性疾病的研究，例如结膜炎和支气管哮喘。Chloropyramine 表现出抗乳腺癌活性。
T60289	Pemirolast
	Pemirolast 是一种具有口服活性的抗过敏剂。Pemirolast 通过抑制感觉神经肽的释放来减轻紫杉醇超敏反应，可用于对支气管哮喘和结膜炎的研究。
T22189	APC 366
	APC 366 是肥大细胞类胰蛋白酶 (tryptase) 的选择性抑制剂，Ki 值为7.1 μM。在羊过敏性哮喘模型中，APC 366 抑制抗原诱导的早期哮喘反应 (EAR)、晚期哮喘反应 (LAR) 和支气管高反应性 (BHR)。
T71155	NP-1815-PX	P2X Receptor	Membrane transporter/Ion channel; Neuroscience
	NP-1815-PX是一种选择性P2X4R拮抗剂，显示出抗炎活性并可缓解慢性疼痛模型的疼痛症状。此外，NP-1815-PX能够抑制豚鼠气管/支气管平滑肌（TSM和BSM）的收缩。
T0246L	Betahistine mesylate Extovyl,甲磺酸倍他司汀,Melopat,Meginalisk	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Betahistine mesylate (Extovyl) 是可口服的组胺 H1 受体激动剂和 H3 受体的拮抗剂，可用作血管扩张剂，用于类风湿性关节炎的研究。
T80891	Urodilatin
	Urodilatin为ANF-(99-126)的同类物，属于利尿钠调节肽。该化合物主要应用于急性肾功能衰竭、充血性心力衰竭、支气管哮喘等疾病的研究领域。
T70153	Pipoxolan hydrochloride
	Pipoxolan (HCl) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual cramp...
T71329	Theophylline-d6
	Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. F...
T76320	FIZZ-1 (32-51) (mouse)
	FIZZ-1 (32-51) (mouse) 是一种富含半胱氨酸的分泌性蛋白，主要在过敏性气道炎症中被巨噬细胞、支气管上皮细胞及II型肺泡上皮细胞高度表达，具有对肺成纤维细胞的抗凋亡功能，广泛应用于过敏性肺炎的研究领域。
T70377	BAY 61-3606 HCl
	BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was shown to suppress antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema. It can also sensitize MCF-7 breast cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis by inhibiting Cdk9. This compound has been used i...
T21633	N-3-oxo-dodecanoyl-L-Homoserine lactone
	N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) 是由铜绿假单胞菌和洋葱状芽孢杆菌复合物菌株产生的细菌群体感应信号分子，群体感应是细菌用来控制基因表达以响应细胞密度增加的调节系统。N-3-oxo-dodecanoyl-L-Homoserine lactone 诱导 16HBE 人支气管上皮细胞产生 IL-8。
T69661	Pipoxolan (free base)
	Pipoxolan (free base) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual...

化合物

Cromoglicic acid

Cat.No: T8239

Target: Others

Cat.No: T9350

Target: Others, DNA/RNA Synthesis

Cat.No: T3965

Synonym: QAW039,NVP-QAW039,非维匹仑

Target: GPR, Prostaglandin Receptor

Fluticasone (propionate)

Cat.No: T0188

Synonym: 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate

Target: Glucocorticoid Receptor, Virus Protease, Estrogen/progestogen Receptor, Phospholipase, Endogenous Metabolite

Cat.No: T5872

Synonym: 灭菌丹,Folpet

Target: Antifungal

Metaproterenol hemisulfate

Cat.No: T0277

Synonym: Orciprenaline sulfate,Metaproterenol Sulfate,硫酸奥西那林

Target: Adrenergic Receptor

Trans-Tranilast

Cat.No: T2270

Synonym: Tranilast trans-,反式-曲尼司特,反-曲尼司特

Target: RAAS

Cat.No: T0477

Synonym: Abbott 64077,齐留通,A 64077

Target: Ferroptosis, Lipoxygenase, COX

Bethanechol chloride

Cat.No: T3126

Synonym: (±)-Bethanechol,Urecholine,Myocholine,氯贝胆碱,Carbamyl-β-methylcholine chloride

Target: AChR

Cat.No: T4195

Synonym: PT 9 base,倍他司汀,Vasomotal,Serc base

Target: Histamine Receptor

Ipratropium bromide monohydrate

Cat.No: T0098

Synonym: Ipratropium bromide hydrate,溴化异丙托品单水合物

Target: AChR

Cat.No: T60522

Synonym: Viscotiol

Target: Others

Doxylamine succinate

Cat.No: T1115

Synonym: 琥珀酸多西拉敏,Decapryn

Target: Histamine Receptor

Acebutolol hydrochloride

Cat.No: T1012

Synonym: 盐酸醋丁洛尔,Acebutolol HCl

Target: Adrenergic Receptor

Propantheline bromide

Cat.No: T1006

Synonym: Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl

Target: AChR

Methacholine Chloride

Cat.No: T1682

Synonym: 醋甲胆碱,Mecholyl chloride,氯化乙酰甲胆碱,Acetyl-β-methylcholine chloride

Target: AChR

Cat.No: T1139

Synonym: Albuterol,沙丁胺醇,AH-3365

Target: Adrenergic Receptor

Theophylline monohydrate

Cat.No: T1083L

Synonym: Quibron,茶碱一水合物

Target: HDAC, PDE, Adenosine Receptor

N-Acetyl lysyltyrosylcysteine amide

Cat.No: T38063

Target: Glutathione Peroxidase

Cat.No: T0920

Synonym: 氨溴索,氨溴索碱,Ambroxolum,NA-872

Target: P450, Autophagy

Cat.No: T36466

Synonym: Ce6,Chlorin e6,CE6

Target: Parasite

Cat.No: T28651

Synonym: S 5751

Cat.No: T30141L

Synonym: Arpenal hydrochloride

Cat.No: T30141

Tranilast Sodium

Cat.No: T23472

Target: Others

Cat.No: T30827

Synonym: Cgp-33304,Cgp33304

Cat.No: T30835

Synonym: Cgp45715A,Cgp-45715A

KAA-276 free base

Cat.No: T70294

RNF5 inhibitor inh-02

Cat.No: T35883

Synonym: RNF5 inhibitor inh-02

Cat.No: T61702

Cat.No: T70293

Cat.No: T61075

Antazoline phosphate

Cat.No: T21020

Ipratropium Free Base

Cat.No: T69025

Cat.No: T21411

Synonym: Norisodrine,Isoprenaline,Novodrin,Isuprel,Medihaler-Iso

Target: Endogenous Metabolite, Adrenergic Receptor

Cat.No: T121458

Cat.No: T26628

Synonym: CR2039,CR-2039,CR 2039

Cat.No: T61306

Cat.No: T60590

Cat.No: T60289

Cat.No: T22189

Cat.No: T71155

Target: P2X Receptor

Betahistine mesylate

Cat.No: T0246L

Synonym: Extovyl,甲磺酸倍他司汀,Melopat,Meginalisk

Target: Histamine Receptor

Cat.No: T80891

Pipoxolan hydrochloride

Cat.No: T70153

Theophylline-d6

Cat.No: T71329

FIZZ-1 (32-51) (mouse)

Cat.No: T76320

BAY 61-3606 HCl

Cat.No: T70377

N-3-oxo-dodecanoyl-L-Homoserine lactone

Cat.No: T21633

Pipoxolan (free base)

Cat.No: T69661

Cat. No.	Product Name	Target	Signaling Pathways
T0892	Diphylline 二羟丙茶碱,Dyphylline,Diprophylline	PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Diphylline (Diprophylline) 是一种A1/A2腺苷受体拮抗剂，也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物，具有支气管扩张和血管扩张作用，有用于治疗慢性支气管炎和肺气肿的潜力。
T0962	L-Hyoscyamine Daturine,Hyoscyamine,L-莨菪碱,L-天仙子胺	AChR	Neuroscience
	L-Hyoscyamine (Daturine) 是从山莨菪中提取的一种托烷生物碱，是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。
T0965	Histamine Ergamine,组胺	5-HT Receptor; Endogenous Metabolite; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Histamine (Ergamine) 是通过组胺的酶促脱羧衍生的胺。它是一种强大的胃分泌兴奋剂、支气管平滑肌的收缩剂、血管扩张剂以及中枢作用的神经递质。
T4S1619	L-Hyoscyamine sulfate Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate,硫酸天仙子胺水合物,L-莨菪碱硫酸盐	AChR	Neuroscience
	L-Hyoscyamine sulfate (Levsin Sulfate) 是来自山莨菪的一种托烷生物碱，是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。
T6534	Histamine dihydrochloride 组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl	Endogenous Metabolite; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Histamine dihydrochloride (Ceplene) 是 Histamine 的二盐酸形式。Histamine 是一种有机氮化合物，是一种强效的胃分泌兴奋剂，支气管平滑肌收缩剂，血管舒张剂，也是一种中枢作用的神经递质。
T7962	Coumalic acid 香豆酸,Cumalic Acid	Others	Others
	Coumalic acid (Cumalic Acid) 可以由苹果酸制备。它可用于香料、调味剂及化妆品工业生产中。它作为聚合物组分以及具有抗支气管和疟疾活性的活性分子支架。
T1083	Theophylline Theo-24,1,3-Dimethylxanthine,茶碱	Endogenous Metabolite; HDAC; PDE; Adenosine Receptor; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Theophylline (1,3-Dimethylxanthine) 是茶中的甲基黄嘌呤衍生物，具有利尿、平滑肌松弛、支气管扩张、心脏和中枢神经系统兴奋作用。
T2520	Desloratadine Sch34117,地氯雷他定,NSC 675447	Endogenous Metabolite; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Desloratadine (Sch34117) 是非镇静H1抗组胺药 Loratadine 的主要口服代谢物，可减少对支气管平滑肌、毛细血管和胃肠道平滑肌中 H1 受体的典型组胺能作用，包括血管舒张、支气管收缩、血管通透性增加、疼痛、瘙痒和胃肠道平滑肌的痉挛性收缩。它是一种选择性H1受体拮抗剂，具有抗过敏和抗炎活性。
TMA0955	Thunberginol C	Antifection	Microbiology/Virology
	Thunberginol C exhibits antimicrobial activity against oral bacteria. It shows antiallergic activity in the in vitro bioassay using the Schults-Dale reaction in sensitized guinea pig bronchial muscle.

天然产物

Cat.No: T0892

Synonym: 二羟丙茶碱,Dyphylline,Diprophylline

Target: PDE, Adenosine Receptor

Cat.No: T0962

Synonym: Daturine,Hyoscyamine,L-莨菪碱,L-天仙子胺

Target: AChR

Cat.No: T0965

Synonym: Ergamine,组胺

Target: 5-HT Receptor, Endogenous Metabolite, Histamine Receptor

L-Hyoscyamine sulfate

Cat.No: T4S1619

Synonym: Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate,硫酸天仙子胺水合物,L-莨菪碱硫酸盐

Target: AChR

Histamine dihydrochloride

Cat.No: T6534

Synonym: 组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl

Target: Endogenous Metabolite, Histamine Receptor

Cat.No: T7962

Synonym: 香豆酸,Cumalic Acid

Target: Others

Cat.No: T1083

Synonym: Theo-24,1,3-Dimethylxanthine,茶碱

Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy

Cat.No: T2520

Synonym: Sch34117,地氯雷他定,NSC 675447

Target: Endogenous Metabolite, Histamine Receptor

Cat.No: TMA0955

Target: Antifection

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