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Search Results for " azole "

483

抑制剂 & 化合物

42

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T41244	Triticonazole	Antifungal	Microbiology/Virology
	Triticonazole 是一种三唑类农药。它具有杀菌和干扰内分泌作用。
T11991	Mefentrifluconazole	P450; Antifungal	Metabolism; Microbiology/Virology
	Mefentrifluconazole 是一种有效的、选择性的和具有口服活性的真菌 CYP51 (Kd= 0.5 nM) 抑制剂，但对人芳香酶的抑制活性较低，IC50值为0.92 μM。它是一种新型唑类衍生物，用作农用广谱抗真菌剂。
T0195	Secnidazole RP-14539,PM-185184,塞克硝唑	Antibiotic; Parasite	Microbiology/Virology
	Secnidazole (PM-185184) 是一种具有口服活性唑类抗生素，半衰期比甲硝唑更长。它有潜力研究细菌性阴道病。
T22636	Phenyl-benzothiazole 2-(p-Aminophenyl)-6-methylbenzothiazole,4-(6-methyl-1,3-benzothiazol-2-yl)aniline,2-(4-Aminophenyl)-6-methylbenzothiazole,Dehydrothio-p-toluidine,2-(4-氨基苯基)-6-甲基苯并噻唑	Others	Others
	Phenyl-benzothiazole (2-(4-Aminophenyl)-6-methylbenzothiazole) 是一种用于蛋白质组学研究的唑类。
T6550	Isoconazole nitrate 硝酸异康唑,Travogyn,Fazol	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Isoconazole nitrate (Fazol) 是一种唑类抗真菌试剂。它具有强效的抗真菌和革兰氏阳性菌的活性，以及快速吸收和系统性暴露低的特点。
T2333	Efinaconazole KP-103,艾氟康唑	Antifungal	Microbiology/Virology
	Efinaconazole (KP-103) 是一种三唑类抗真菌剂，抑制T. mentagrophytesSM-110和C. albicansATCC 10231菌株的MIC 值分别为 0.0039 μg/mL 和 0.00098 μg/mL
T6499	Fenticonazole Nitrate REC 15-1476,硝酸芬替康唑,Falvin,Lomexin	Antibiotic; Antifungal	Microbiology/Virology
	Fenticonazole Nitrate (Lomexin) 是一种抗真菌的咪唑环衍生物。它阻止麦角固醇整合和依次破坏细胞质外膜起作用。它对革兰氏阳性菌，真菌病和阴道念珠菌病有效。
T2411	Luliconazole NND 502,卢立康唑	Antibiotic; Antifungal	Microbiology/Virology
	Luliconazole (NND 502) 是一种咪唑类抗生素，具有广谱抗真菌活性。它可研究皮肤感染。
T7824	Eberconazole Nitrate 硝酸依柏康唑,Ebernet	Antifungal	Microbiology/Virology
	Eberconazole Nitrate (Ebernet) 是一种二氯咪唑衍生物，具有抗真菌活性，效果比Ketoconazole、Clotrimazole 和Miconazole 强。它通过局部给药对皮肤癣菌病具有潜在的研究价值。
T17022	Tebuconazole	P450; Antifungal	Metabolism; Microbiology/Virology
	Tebuconazole 是一种农用唑类杀菌剂，可抑制 CYP51，对白色念珠菌 CYP51 和truncated Homo sapiens CYP51 的IC50分别为 0.9 和 1.3 μM。
T2305	Isavuconazole 艾沙康唑,BAL-4815,RO-0094815	P450; Antibiotic; Antifungal	Metabolism; Microbiology/Virology
	Isavuconazole (RO-0094815) 是一种三唑类前药，对酵母、霉菌和二型真菌具有抗真菌活性。它抑制麦角固醇生物合成，导致真菌膜结构和功能的破坏。它是 CYP3A4抑制剂。
T1290	Oxiconazole nitrate 硝酸奥昔康唑,Ro 13-8996	Others; Antibiotic; Antifection; Antifungal	Microbiology/Virology; Others
	Oxiconazole nitrate (Ro 13-8996) 是广谱抗真菌药物，抑制T. tonsurans 和T.rubrum 的生长，MIC90值分别为 0.25 和 0.5 μg/mL。
T21022	Deacylketoconazole Deacyl ketoconazole,脱乙酰酮康唑	Antifungal	Microbiology/Virology
	Deacylketoconazole (Deacyl ketoconazole) 是一种酮康唑衍生物，也是一种抗真菌剂。脱酰基酮康唑对恶性疟原虫的活性是酮康唑的 15 至 50 倍。
TQ0128	Furilazole MON 13900,解草恶唑	Others	Others
	Furilazole (MON 13900) 是一种农药剂。
T31362	Deferitazole SPD602,FBS 0701,SPD-602,FBS0701,FBS-0701,SPD 602	Others	Others
	Deferitazole (FBS 0701) 是一种新型且具有口服活性、选择性和高亲和力的铁螯合剂。
T14871	Carboxyamidotriazole Orotate L-651582 Orotate,CAI Orotate	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Carboxyamidotriazole Orotate (L-651582 Orotate) 是一种可口服的信号转导抑制剂，是Carboxyamidotriazole (CAI) 的乳清酸盐形式。它是一种非电压性钙通道和钙通道介导的信号通路的细胞抑制剂，具有抗癌、抗炎活性和抗血管生成作用。
T4239	1,3-dimethyl-2-oxobenzimidazole-5-carbaldehyde 1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOLE-5-CARBALDEHYDE	Others	Others
	1,3-dimethyl-2-oxobenzimidazole-5-carbaldehyde 是中间体。
T20714	Levolansoprazole 左旋兰索拉唑,(S)-Lansoprazole,(-)-Lansoprazole	Proton pump	Membrane transporter/Ion channel
	Levolansoprazole ((S)-Lansoprazole) 是一种质子泵抑制剂，不可逆地抑制壁细胞中 H+/K+ 刺激的 ATPase 泵 (IC50: 5.2 µM)。它还抑制分离的犬壁细胞中的酸形成(IC50：82 µM)。 (R)-和 (S)-兰索拉唑均具有药理活性，具有相似的效力。
T4985	Neticonazole Hydrochloride	Antifungal	Microbiology/Virology
	Neticonazole hydrochloride 是一种咪唑衍生物，具有抗感染和抗癌作用。它也是一种长效抗真菌剂。
T50032	5-(2-furyl)-N-propylisoxazole-3-carboxamide	Others	Others
	5-(2-furyl)-N-propylisoxazole-3-carboxamide 是一种用作分子结构单元的化合物，被认为是 NMDA 受体的调节剂，已被证明对神经元细胞中谷氨酸诱导的兴奋性毒性和氧化应激具有保护作用。它也被发现具有抗炎活性，使其成为阿尔茨海默病和帕金森病等疾病的潜在治疗剂。
T19673	Fuberidazole	Antifungal	Microbiology/Virology
	Fuberidazole 是一种抗真菌剂。
T0575	1-Methylimidazole	Others	Others
	1-Methylimidazole 是1-methyl-2-thioimidazole (methimazole)的代谢物，可抑制骨吸收。
T0644	3-Amino-5-methylisoxazole	Others	Others
	3-Amino-5-methylisoxazole 是医药中间体，用于生产磺胺类药物。
T10138	4-Desmethoxy Omeprazole	Drug Metabolite	Metabolism
	4-Desmethoxy Omeprazole 是 Omeprazole 的活性代谢物。Omeprazole 是质子泵抑制剂。Omeprazole 竞争性抑制 CYP2C19 活性，Ki=2 - 6 μM。Omeprazole 还抑制革兰氏阴性菌和革兰氏阳性菌生长。
T19826	Rabeprazole LY307640	Potassium Channel; STAT	JAK/STAT signaling; Membrane transporter/Ion channel; Stem Cells
	Rabeprazole (LY307640) 是一种 H+/K+-ATPase 抑制剂，通过靶向 STAT3 介导的糖酵解来抑制胃上皮细胞中的细胞增殖，可用于研究胃溃疡。
T16536	Pimonidazole hydrochloride
	Pimonidazole hydrochloride 通过与大分子共价结合或在其硝基还原后形成还原性代谢物在缺氧细胞中积累。可用于肿瘤缺氧的定性和定量评估。它是一种新型的缺氧标志物，用于肿瘤缺氧和肿瘤细胞增殖的互补研究。
T15033	Cyproconazole	Antibacterial	Microbiology/Virology
	Cyproconazole 是一种三唑类杀菌剂，在农业上用于保护作物免受多种真菌病原体的侵害。
T11013L2	Levorotation nimorazole phosphate ester TFA	Others	Others
	Levorotation nimorazole phosphate ester TFA 是一种抗厌氧菌和抗原虫感染的试剂。
T28174	Niridazole BA32644,BA-32644,Ambilhar,BA 32644
	Niridazole (Ambilhar) 是一种具有抗寄生虫活性的化合物，属于硝基咪唑类化合物。Niridazole 主要用于治疗血吸虫病，通过干扰寄生虫的新陈代谢，导致其死亡。Niridazole 在寄生虫体内迅速集中，抑制卵子和精子的发生，抑制磷酸果糖激酶活性。
T3445	Importazole	Apoptosis; Others	Apoptosis; Others
	Importazole 是一种核转运受体 importin-β 小分子抑制剂。
T25982	Pramiconazole R-126638,R126638,R 126638,Azoline	Antifungal	Microbiology/Virology
	Pramiconazole (R126638) 是一种可口服的抗真菌化合物。Pramiconazole 是治疗皮肤癣菌和皮肤酵母菌感染的候选化合物，可用于治疗脂溢性皮炎。
T1756L	Ilaprazole IY81149,艾普拉唑,IY 81149,IY-81149	Proton pump; TOPK	MAPK; Membrane transporter/Ion channel
	Ilaprazole (IY-81149) 是一种具有口服活性质子泵抑制剂，以剂量依赖性方式不可逆地抑制H+/K+-ATPase，在兔壁细胞制剂中的IC50为 6 μM。它也是一种有效的T 细胞起源蛋白激酶(TOPK)抑制剂，用于胃溃疡的研究。
T0444L	Econazole nitrate NSC 243115,硝酸益康唑	Antibacterial; Antibiotic; Antifection; Antifungal	Microbiology/Virology
	Econazole nitrate (NSC-243115) 是一种有抗菌活性的咪唑类抗真菌药物。
T1187	Bifonazole 联苯苄唑,Bay H-4502	P450; Antibiotic; Antifungal	Metabolism; Microbiology/Virology
	Bifonazole (Bay H-4502) 是咪唑类抗真菌剂。
T5328	Fosfluconazole	Antifungal	Microbiology/Virology
	Fosfluconazole 是 fluconazole 的水溶性磷酸盐前药。它是一种抗真菌药物。
T61148	Flutrimazole	Antifungal	Microbiology/Virology
	Flutrimazole是一种具有双重作用的咪唑类抗真菌化合物，展现出抗炎和抗真菌的属性。值得注意的是，flutrimazole的经皮渗透性有限，这使其在治疗伴有炎症的真菌感染的局部应用中特别有优势。
T8599	Betazole dihydrochloride 盐酸倍他唑,Betazole hydrochloride	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Betazole dihydrochloride (Betazole hydrochloride) 是吡唑类组胺，是一种口服活性 H2受体激动剂，能诱导胃酸分泌，导致胆总管压力立即显著升高。它作为一种诊断剂，用于研究胃酸分泌能力。
T7474	7-Nitroindazole	NOS	Immunology/Inflammation
	7-Nitroindazole 是一种具有抗损伤及心血管作用的选择性nNOS 抑制剂，也是评价一氧化氮在中枢神经系统中生物学效应的有效工具。
T1438	Butoconazole nitrate RS 35887,硝酸布康唑	Estrogen/progestogen Receptor; Antifungal	Endocrinology/Hormones; Microbiology/Virology
	Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物，可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。
T0952	Carbimazole 卡比马唑,Athyromazole,卡比吗唑,Carbimazol,Neomercazole	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Carbimazole (Athyromazole) 是咪唑类甲状腺拮抗试剂，在体内快速转化为 MMI 而发挥作用，在体外可转化为甲咪唑，可用于 Graves 病的研究。
T2687	Omeprazole sulfide Omeprazole metabolite Omeprazole sulfide,Ufiprazole,奥美拉唑硫醚	Proton pump; Drug Metabolite	Membrane transporter/Ion channel; Metabolism
	Omeprazole sulfide (Ufiprazole) 是 Omeprazole 的代谢物。
T5966	Hexaconazole 己唑醇,(-)-Hexaconazol	Reactive Oxygen Species; Antifungal	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Hexaconazole ((-)-Hexaconazol) 是一种广谱三唑类杀菌剂，通过抑制羊毛甾醇的细胞色素 P450 依赖性 14α-去甲基化来抑制麦角甾醇的生物合成，从而导致真菌细胞膜的破坏和细胞死亡。
T1647	Ronidazole 洛硝哒唑,Ronidazol,罗硝唑,Ridzol	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ronidazole (Ronidazol) 是一种口服有效的抗原虫和抗菌试剂。它在猫模型中对胎儿三毛滴虫有效，还可研究组织口癣和猪痢疾。
T2686	Esomeprazole Magnesium (S)-Omeprazole magnesium,NEXIUM,埃索美拉唑镁,(-)-Omeprazole magnesium	ATPase; Proton pump	Membrane transporter/Ion channel
	Esomeprazole Magnesium (NEXIUM) 是一种口服有效的 H+, K+-ATPase 抑制剂，在上消化道疾病和胃食管反流疾病中具有研究价值。Esomeprazole magnesium 是一种外泌体抑制剂，通过抑制 V-H+-ATPases 来阻断外泌体的释放。
T12096L	Morinidazole	Antibacterial	Microbiology/Virology
	Morinidazole 具有抗菌活性，可用于厌氧菌引起的阑尾炎、盆腔炎等细菌感染研究。
T0874	Dimetridazole 1, 2-Dimethyl-5-nitroimidazole,1,2-Dimethyl-5-nitroimidazole,二甲硝咪唑	Antibiotic; Parasite	Microbiology/Virology
	Dimetridazole (1, 2-Dimethyl-5-nitroimidazole) 是一种对抗原生动物感染的硝基咪唑类药物。
T0714	Oxfendazole 奥吩达唑,奥芬哒唑,RS-8858	Glucokinase; Microtubule Associated; Parasite	Cytoskeletal Signaling; Metabolism; Microbiology/Virology
	Oxfendazole (RS-8858) 是fenbendazole 的亚砜形式，是广谱苯并咪唑驱虫剂，可保护牲畜免受蛔虫、圆线虫和蛲虫的侵害。
T14319	Aripiprazole Lauroxil	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Aripiprazole lauroxil 是一种长效注射剂 (LAI) 的抗精神病药物，是阿立哌唑的 N-酰氧基甲基前药形式。它能够被体内酯酶裂解为 N-羟甲基阿立哌唑(月桂酸)，再裂解为阿立哌唑，无毒性。
T77598	Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone	Others	Others
	Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) 是一种生物合成的原材料，可用于合成多种化合物。
T5955	Tricyclazole 三环唑,Tricyclazol	Antibacterial	Microbiology/Virology
	Tricyclazole (Tricyclazol) 是一种源自五肽的黑色素生物合成抑制剂，是一种独特的杀菌剂，用于防治水稻稻瘟病菌。

化合物

Cat.No: T41244

Target: Antifungal

Mefentrifluconazole

Cat.No: T11991

Target: P450, Antifungal

Cat.No: T0195

Synonym: RP-14539,PM-185184,塞克硝唑

Target: Antibiotic, Parasite

Phenyl-benzothiazole

Cat.No: T22636

Synonym: 2-(p-Aminophenyl)-6-methylbenzothiazole,4-(6-methyl-1,3-benzothiazol-2-yl)aniline,2-(4-Aminophenyl)-6-methylbenzothiazole,Dehydrothio-p-toluidine,2-(4-氨基苯基)-6-甲基苯并噻唑

Target: Others

Isoconazole nitrate

Cat.No: T6550

Synonym: 硝酸异康唑,Travogyn,Fazol

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T2333

Synonym: KP-103,艾氟康唑

Target: Antifungal

Fenticonazole Nitrate

Cat.No: T6499

Synonym: REC 15-1476,硝酸芬替康唑,Falvin,Lomexin

Target: Antibiotic, Antifungal

Cat.No: T2411

Synonym: NND 502,卢立康唑

Target: Antibiotic, Antifungal

Eberconazole Nitrate

Cat.No: T7824

Synonym: 硝酸依柏康唑,Ebernet

Target: Antifungal

Cat.No: T17022

Target: P450, Antifungal

Cat.No: T2305

Synonym: 艾沙康唑,BAL-4815,RO-0094815

Target: P450, Antibiotic, Antifungal

Oxiconazole nitrate

Cat.No: T1290

Synonym: 硝酸奥昔康唑,Ro 13-8996

Target: Others, Antibiotic, Antifection, Antifungal

Deacylketoconazole

Cat.No: T21022

Synonym: Deacyl ketoconazole,脱乙酰酮康唑

Target: Antifungal

Cat.No: TQ0128

Synonym: MON 13900,解草恶唑

Target: Others

Cat.No: T31362

Synonym: SPD602,FBS 0701,SPD-602,FBS0701,FBS-0701,SPD 602

Target: Others

Carboxyamidotriazole Orotate

Cat.No: T14871

Synonym: L-651582 Orotate,CAI Orotate

Target: Calcium Channel

1,3-dimethyl-2-oxobenzimidazole-5-carbaldehyde

Cat.No: T4239

Synonym: 1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOLE-5-CARBALDEHYDE

Target: Others

Levolansoprazole

Cat.No: T20714

Synonym: 左旋兰索拉唑,(S)-Lansoprazole,(-)-Lansoprazole

Target: Proton pump

Neticonazole Hydrochloride

Cat.No: T4985

Target: Antifungal

5-(2-furyl)-N-propylisoxazole-3-carboxamide

Cat.No: T50032

Target: Others

Cat.No: T19673

Target: Antifungal

1-Methylimidazole

Cat.No: T0575

Target: Others

3-Amino-5-methylisoxazole

Cat.No: T0644

Target: Others

4-Desmethoxy Omeprazole

Cat.No: T10138

Target: Drug Metabolite

Cat.No: T19826

Synonym: LY307640

Target: Potassium Channel, STAT

Pimonidazole hydrochloride

Cat.No: T16536

Cat.No: T15033

Target: Antibacterial

Levorotation nimorazole phosphate ester TFA

Cat.No: T11013L2

Target: Others

Cat.No: T28174

Synonym: BA32644,BA-32644,Ambilhar,BA 32644

Cat.No: T3445

Target: Apoptosis, Others

Cat.No: T25982

Synonym: R-126638,R126638,R 126638,Azoline

Target: Antifungal

Cat.No: T1756L

Synonym: IY81149,艾普拉唑,IY 81149,IY-81149

Target: Proton pump, TOPK

Econazole nitrate

Cat.No: T0444L

Synonym: NSC 243115,硝酸益康唑

Target: Antibacterial, Antibiotic, Antifection, Antifungal

Cat.No: T1187

Synonym: 联苯苄唑,Bay H-4502

Target: P450, Antibiotic, Antifungal

Cat.No: T5328

Target: Antifungal

Cat.No: T61148

Target: Antifungal

Betazole dihydrochloride

Cat.No: T8599

Synonym: 盐酸倍他唑,Betazole hydrochloride

Target: Histamine Receptor

7-Nitroindazole

Cat.No: T7474

Target: NOS

Butoconazole nitrate

Cat.No: T1438

Synonym: RS 35887,硝酸布康唑

Target: Estrogen/progestogen Receptor, Antifungal

Cat.No: T0952

Synonym: 卡比马唑,Athyromazole,卡比吗唑,Carbimazol,Neomercazole

Target: Thyroid hormone receptor(THR)

Omeprazole sulfide

Cat.No: T2687

Synonym: Omeprazole metabolite Omeprazole sulfide,Ufiprazole,奥美拉唑硫醚

Target: Proton pump, Drug Metabolite

Cat.No: T5966

Synonym: 己唑醇,(-)-Hexaconazol

Target: Reactive Oxygen Species, Antifungal

Cat.No: T1647

Synonym: 洛硝哒唑,Ronidazol,罗硝唑,Ridzol

Target: Antibacterial, Antibiotic, Parasite

Esomeprazole Magnesium

Cat.No: T2686

Synonym: (S)-Omeprazole magnesium,NEXIUM,埃索美拉唑镁,(-)-Omeprazole magnesium

Target: ATPase, Proton pump

Cat.No: T12096L

Target: Antibacterial

Cat.No: T0874

Synonym: 1, 2-Dimethyl-5-nitroimidazole,1,2-Dimethyl-5-nitroimidazole,二甲硝咪唑

Target: Antibiotic, Parasite

Cat.No: T0714

Synonym: 奥吩达唑,奥芬哒唑,RS-8858

Target: Glucokinase, Microtubule Associated, Parasite

Aripiprazole Lauroxil

Cat.No: T14319

Target: Dopamine Receptor, 5-HT Receptor

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine

Cat.No: T77598

Synonym: (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone

Target: Others

Cat.No: T5955

Synonym: 三环唑,Tricyclazol

Target: Antibacterial

Cat. No.	Product Name	Target	Signaling Pathways
TN7167	2,4,5-Tribromoimidazole 2,4,5-三溴咪唑,2,4,5-Tribromo-1H-imidazole	Others	Others
	2,4,5-Tribromoimidazole (2,4,5-Tribromo-1H-imidazole) 是一种海洋来源的天然产物，存在于 Hexaplex trunculus。
T4842	1H-pyrazole 1,2-Diazole,Pyrazole,吡唑	Others; Endogenous Metabolite	Metabolism; Others
	1H-pyrazole (1,2-Diazole) 是内源性代谢产物的一种。
TN7165	3,6-Dibromocarbazole 3,6-Dibromo-9H-carbazole,3，6二溴咔唑	Others	Others
	3,6-Dibromocarbazole (3,6-Dibromo-9H-carbazole) 是一种海洋来源的天然产物，存在于Kyrtuthrix maculans。
T0344L	Miconazole nitrate NSC 169434 Nitrate,硝酸咪康唑,R18134 nitrate	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Miconazole nitrate (R18134 nitrate) 是咪唑类可抗菌的抗真菌剂。
T21651	Lansoprazole sodium 兰索拉唑钠,Lansoprazole (sodium), AG-1749 sodium	Proton pump; Phospholipase; Antibacterial	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Lansoprazole sodium (Lansoprazole (sodium)) 是一种质子泵抑制剂，是中性鞘磷脂酶的外泌体抑制剂，能抑制胃酸生成。
T7132	(Rac)-Brassinazole BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑	P450	Metabolism
	(Rac)-Brassinazole 是三唑型化合物，是油菜素甾醇 (BR) 生物合成抑制剂。它能够增强 CYP90B 在 BR 生物合成中的抑制作用。
T19856	2-Mercaptobenzothiazole Mercaptobenzothiazole,Dermacid,2-巯基苯并噻唑,Captax	Others; Endogenous Metabolite	Metabolism; Others
	2-Mercaptobenzothiazole (Captax) 是内源性代谢产物的一种。
T0444	Econazole (±)-Econazol,益康唑	Antibiotic; Antifection; Antifungal	Microbiology/Virology
	Econazole ((±)-Econazol) 是一种咪唑衍生物，是一种抗真菌剂。
T5202	Imidazole Glyoxaline,1,3-Diaza-2,4-cyclopentadiene,1,3-diazole,咪唑	Others	Others
	Imidazole 是一种高极性化合物，是一种平面五元环，已被广泛用作腐蚀抑制剂。
TN7175	9H-Carbazole, 3,6-diiodo- 3,6-Diiodo-9H-carbazole,3,6-diiodocarbazole,3,6-二碘-9H-咔唑	Others	Others
	9H-Carbazole, 3,6-diiodo- (3,6-diiodocarbazole)是一种海洋来源的天然产物，存在于Kyrtuthrix maculans。
T0146	Tioconazole UK-20349,Vagistat,噻康唑	Antibiotic; Antifection; Antifungal	Microbiology/Virology
	Tioconazole (Vagistat) 是一种广谱性的抗真菌咪唑衍生物。它抑制几种皮肤真菌和几种酵母菌的 MIC50分别小于 3.12 mg/L 和 9 mg/L。
T1556	Ornidazole Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ornidazole (Tiberal) 是一种5-硝基咪唑衍生物，能抗原生动物和厌氧菌。
T1388	Fluconazole 氟康唑,UK-49858	Antibiotic; Antifection; Antifungal	Microbiology/Virology
	Fluconazole (UK-49858) 是一种对多种真菌具有活性的三唑类抗真菌剂，抑制 C. albicans 和 Candida kefyr 的 IC99为 0.20 μg/mL 至 0.39 μg/mL。
T1705	5-Amino-3H-imidazole-4-Carboxamide 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide	Endogenous Metabolite	Metabolism
	5-Amino-3H-imidazole-4-Carboxamide (AICA) 是一种合成嘌呤（尤其是核碱基腺嘌呤和鸟嘌呤）的重要前体。
TN7203	9H-Carbazole, 1-methyl- 1-甲基咔唑,1-Methyl-carbazole,1-Methyl-9H-carbazole,1-methyl carbazole	Others	Others
	9H-Carbazole, 1-methyl- (1-methyl carbazole)是一种海洋来源的天然产物，存在于Tedania (Tedania) ignis。
T1011	Itraconazole 伊曲康唑,R51211	P450; Hedgehog/Smoothened; Antibiotic; Autophagy; Antifungal	Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Stem Cells
	Itraconazole (R51211) 是三唑类抗真菌药，也是口服活性的Hedgehog 信号通路拮抗剂，IC50约为 800 nM。它也是 oxysterol-binding protein 抑制剂。它抑制羊毛甾醇 14α-脱甲基酶，从而抑制羊毛甾醇向麦角固醇的氧化转化。它有抗癌和抗血管作用。
TN7164	2,7-Dibromo-9H-Carbazole 2,7-Dibromocarbazole,2,7-二溴咔唑	Others	Others
	2,7-Dibromo-9H-Carbazole (2,7-Dibromocarbazole) 是一种海洋来源的天然产物，存在于Kyrtuthrix maculans。
T1152	Albendazole SKF-62979,阿苯达唑	HIF/HIF Prolyl-Hydroxylase; Microtubule Associated; Antibiotic; Parasite	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Microbiology/Virology
	Albendazole (SKF-62979) 是一种广谱抗寄生虫剂，具有高效，低宿主毒性的特点。它用于研究人类和动物的胃肠道寄生虫。
T1155	Mebendazole 甲苯达唑,甲苯咪唑,Telmin,Mebenvet,Vermox,Pantelmin	Apoptosis; Microtubule Associated; Parasite	Apoptosis; Cytoskeletal Signaling; Microbiology/Virology
	Mebendazole (Mebenvet) 是一种 hedgehog 抑制剂，用作驱虫药。
T0938	Thiabendazole 2-(4-Thiazolyl)benzimidazole,噻菌灵	Microtubule Associated; Mitochondrial Metabolism; Parasite	Cytoskeletal Signaling; Metabolism; Microbiology/Virology
	Thiabendazole (2-(4-Thiazolyl)benzimidazole) 是具有驱虫特性的苯并咪唑衍生物。
T4824	5,6-Dimethyl-1H-benzo[d]imidazole 5,6-Dimethylbenzimidazole,5,6-二甲基苯并咪唑	Others; Endogenous Metabolite	Metabolism; Others
	5,6-Dimethyl-1H-benzo[d]imidazole (5,6-Dimethylbenzimidazole) 是内源性代谢产物的一种。
T8042	2-Acetylthiazole 2-Acetylthiazole;2 Acetylthiazole,2-Acetylthiazole,2-Thiazolyl methyl ketone,2 Acetylthiazole,1-(2-Thiazolyl)ethanone	Others	Others
	2-Acetylthiazole (2-Acetylthiazole;2 Acetylthiazole) 用于制备手性醇、三唑并噻唑，也用于羟醛缩合反应。
T4753	Imidazoleacetic acid hydrochloride I4AA,(4-Imidazolyl)acetic acid hydrochloride,4-咪唑乙酸盐酸盐,4-Imidazoleacetic acid hydrochloride	Endogenous Metabolite; Antibiotic	Metabolism; Microbiology/Virology
	Imidazoleacetic acid hydrochloride (I4AA) 是咪唑衍生物，具有潜在的抗结核性能。它还用于制备β-分泌酶的酰基胍抑制剂。
T40807	1,3-Dimethylpyrazole 1,3-Dimethyl-1H-pyrazole,2,5-Dimethylpyrazole	Others	Others
	1,3-Dimethylpyrazole (2,5-Dimethylpyrazole) 是一种存在于毛竹根的生物活性物质。
T64343	3-Methylcarbazole NSC 10154	Others	Others
	3-Methylcarbazole (NSC-10154) 是具有抗癌作用的咔唑生物碱化合物。3-Methylcarbazole 对人纤维肉瘤 HT-1080 细胞具有生长抑制活性 (IC50 为 25 μg/mL)。
TN7176	1,3,5-Trimethyl-1H-Pyrazole-4-Carboxylic Acid MFCD00159648,1,3,5-trimethylpyrazole-4-carboxylic acid,trimethyl-1H-pyrazole-4-carboxylic acid,1,3,5-三甲基-1H-吡唑-4-甲酸	Others	Others
	1,3,5-Trimethyl-1H-Pyrazole-4-Carboxylic Acid (1,3,5-trimethylpyrazole-4-carboxylic acid) 是一种海洋来源的天然产物，存在于Cinachyrella sp.。
T1079	Metronidazole Flagyl,Metronidazol,甲硝唑,Anagiardil	Apoptosis; NADPH; Hydrogenase; Antibacterial; Antibiotic; Parasite; Antifection	Apoptosis; Metabolism; Microbiology/Virology
	Metronidazole (Metronidazol) 是一种合成的硝基咪唑衍生物，具有抗原生动物和抗菌活性。
T66965	4-Hydroxymethylpyrazole
	4-Hydroxymethylpyrazole 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T66965，CAS号为 25222-43-9。
TN6217	3-Formylcarbazole
	3-Formylcarbazole 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6217，CAS号为 51761-07-0。
TN6253	7-Hydroxy-1-methoxy-3-methylcarbazole
	7-Hydroxy-1-methoxy-3-methylcarbazole 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6253，CAS号为 107672-54-8。
T35949	4-Carboxypyrazole
	4-Carboxypyrazole is an endogenous metabolite.
TN5611	Aflavazole
	Aflavazole displays significant antifeedant activity against the fungivorous beetle Carpophilus hemipterus.
T13735	Imidazoleacetic acid Imidazolyl-4-acetic acid	Others	Others
	Imidazoleacetic acid, an endogenous ligand, stimulates imidazole receptors.
TN6190	N-Methoxy-3-hydroxymethylcarbazole N-Methoxy-3-hydroxymethyl-9H-carbazole
	N-Methoxy-3-hydroxymethylcarbazole 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6190，CAS号为 142768-49-8。
T81660	Nocarimidazole A
	Nocarimidazole A，一种来源于海洋放线菌Nocardiopsis的白色无定形固体生物碱，具紫外线活性。
T13820	Pi-Methylimidazoleacetic acid	Others	Others
	Pi-Methylimidazoleacetic acid is a potential neurotoxin.
T13464L	(-)-Ketoconazole (-)-R 41400,(-)-Ketoconazol	Others	Others
	(-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers.
TN6194	1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole
	1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6194，CAS号为 484678-79-7。
T38241	2-Aminoimidazole
	2-Aminoimidazole is a potent antibiofilm agent and adjuvant to antimicrobial treatments, which effectively disrupts bacterial self-protection mechanisms by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. Additionally, 2-Aminoimidazole acts as a weak noncompetitive inhibitor of human arginase I, with a Ki value of 3.6 mM[1][2][3].
TN4529	Methyl 3-carbazolecarboxylate
	Methyl 3-carbazolecarboxylate is a natural product from Micromelum sp.
TN6210	N-Methoxy-3-formylcarbazole
	N-Methoxy-3-formylcarbazole 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6210，CAS号为 117592-01-5。
T7910	4-Methoxybenzaldehyde 大茴香醛,Anisaldehyde,p-Anisaldehyde,Anisic aldehyde,4-Anisaldehyde,4-甲氧基苯甲醛,P-Methoxybenzaldehyde	Others; Endogenous Metabolite	Metabolism; Others
	4-Methoxybenzaldehyde (p-Anisaldehyde) 是一种天然存在的芳香酚类化合物，存在于许多植物物种中，包括辣根，茴香，八角茴香等。它是一种能够能的神经毒物，已经表现出致死亡率，吸引力和干扰宿主寻求的影响。

天然产物

2,4,5-Tribromoimidazole

Cat.No: TN7167

Synonym: 2,4,5-三溴咪唑,2,4,5-Tribromo-1H-imidazole

Target: Others

Cat.No: T4842

Synonym: 1,2-Diazole,Pyrazole,吡唑

Target: Others, Endogenous Metabolite

3,6-Dibromocarbazole

Cat.No: TN7165

Synonym: 3,6-Dibromo-9H-carbazole,3，6二溴咔唑

Target: Others

Miconazole nitrate

Cat.No: T0344L

Synonym: NSC 169434 Nitrate,硝酸咪康唑,R18134 nitrate

Target: Antibacterial, Antibiotic, Antifungal

Lansoprazole sodium

Cat.No: T21651

Synonym: 兰索拉唑钠,Lansoprazole (sodium), AG-1749 sodium

Target: Proton pump, Phospholipase, Antibacterial

(Rac)-Brassinazole

Cat.No: T7132

Synonym: BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑

Target: P450

2-Mercaptobenzothiazole

Cat.No: T19856

Synonym: Mercaptobenzothiazole,Dermacid,2-巯基苯并噻唑,Captax

Target: Others, Endogenous Metabolite

Cat.No: T0444

Synonym: (±)-Econazol,益康唑

Target: Antibiotic, Antifection, Antifungal

Cat.No: T5202

Synonym: Glyoxaline,1,3-Diaza-2,4-cyclopentadiene,1,3-diazole,咪唑

Target: Others

9H-Carbazole, 3,6-diiodo-

Cat.No: TN7175

Synonym: 3,6-Diiodo-9H-carbazole,3,6-diiodocarbazole,3,6-二碘-9H-咔唑

Target: Others

Cat.No: T0146

Synonym: UK-20349,Vagistat,噻康唑

Target: Antibiotic, Antifection, Antifungal

Cat.No: T1556

Synonym: Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T1388

Synonym: 氟康唑,UK-49858

Target: Antibiotic, Antifection, Antifungal

5-Amino-3H-imidazole-4-Carboxamide

Cat.No: T1705

Synonym: 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide

Target: Endogenous Metabolite

9H-Carbazole, 1-methyl-

Cat.No: TN7203

Synonym: 1-甲基咔唑,1-Methyl-carbazole,1-Methyl-9H-carbazole,1-methyl carbazole

Target: Others

Cat.No: T1011

Synonym: 伊曲康唑,R51211

Target: P450, Hedgehog/Smoothened, Antibiotic, Autophagy, Antifungal

2,7-Dibromo-9H-Carbazole

Cat.No: TN7164

Synonym: 2,7-Dibromocarbazole,2,7-二溴咔唑

Target: Others

Cat.No: T1152

Synonym: SKF-62979,阿苯达唑

Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite

Cat.No: T1155

Synonym: 甲苯达唑,甲苯咪唑,Telmin,Mebenvet,Vermox,Pantelmin

Target: Apoptosis, Microtubule Associated, Parasite

Cat.No: T0938

Synonym: 2-(4-Thiazolyl)benzimidazole,噻菌灵

Target: Microtubule Associated, Mitochondrial Metabolism, Parasite

5,6-Dimethyl-1H-benzo[d]imidazole

Cat.No: T4824

Synonym: 5,6-Dimethylbenzimidazole,5,6-二甲基苯并咪唑

Target: Others, Endogenous Metabolite

2-Acetylthiazole

Cat.No: T8042

Synonym: 2-Acetylthiazole;2 Acetylthiazole,2-Acetylthiazole,2-Thiazolyl methyl ketone,2 Acetylthiazole,1-(2-Thiazolyl)ethanone

Target: Others

Imidazoleacetic acid hydrochloride

Cat.No: T4753

Synonym: I4AA,(4-Imidazolyl)acetic acid hydrochloride,4-咪唑乙酸盐酸盐,4-Imidazoleacetic acid hydrochloride

Target: Endogenous Metabolite, Antibiotic

1,3-Dimethylpyrazole

Cat.No: T40807

Synonym: 1,3-Dimethyl-1H-pyrazole,2,5-Dimethylpyrazole

Target: Others

3-Methylcarbazole

Cat.No: T64343

Synonym: NSC 10154

Target: Others

1,3,5-Trimethyl-1H-Pyrazole-4-Carboxylic Acid

Cat.No: TN7176

Synonym: MFCD00159648,1,3,5-trimethylpyrazole-4-carboxylic acid,trimethyl-1H-pyrazole-4-carboxylic acid,1,3,5-三甲基-1H-吡唑-4-甲酸

Target: Others

Cat.No: T1079

Synonym: Flagyl,Metronidazol,甲硝唑,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

4-Hydroxymethylpyrazole

Cat.No: T66965

3-Formylcarbazole

Cat.No: TN6217

7-Hydroxy-1-methoxy-3-methylcarbazole

Cat.No: TN6253

4-Carboxypyrazole

Cat.No: T35949

Cat.No: TN5611

Imidazoleacetic acid

Cat.No: T13735

Synonym: Imidazolyl-4-acetic acid

Target: Others

N-Methoxy-3-hydroxymethylcarbazole

Cat.No: TN6190

Synonym: N-Methoxy-3-hydroxymethyl-9H-carbazole

Nocarimidazole A

Cat.No: T81660

Pi-Methylimidazoleacetic acid

Cat.No: T13820

Target: Others

(-)-Ketoconazole

Cat.No: T13464L

Synonym: (-)-R 41400,(-)-Ketoconazol

Target: Others

1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole

Cat.No: TN6194

2-Aminoimidazole

Cat.No: T38241

Methyl 3-carbazolecarboxylate

Cat.No: TN4529

N-Methoxy-3-formylcarbazole

Cat.No: TN6210

4-Methoxybenzaldehyde

Cat.No: T7910

Synonym: 大茴香醛,Anisaldehyde,p-Anisaldehyde,Anisic aldehyde,4-Anisaldehyde,4-甲氧基苯甲醛,P-Methoxybenzaldehyde

Target: Others, Endogenous Metabolite

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