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Search Results for " thrombin "

193

抑制剂 & 化合物

12

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9845	Thrombin inhibitor 5
	Thrombin inhibitor 5 (compound 385) 是一种凝血酶抑制剂，IC50范围为 0.1 μM~1 μM，可用于静脉血栓栓塞的研究。
T7674	Thrombin Receptor Activator for Peptide	Protease-activated Receptor	GPCR/G Protein
	Thrombin Receptor Activator for Peptide 也称为凝血因子 II 受体 (1-5) 或蛋白酶激活受体 1 (1-5)，用于研究冠心病 (CHD)。
T19580	Thrombin (MW 37kDa) 凝血酶,Thrombin	Thrombin	Proteases/Proteasome
	Thrombin (MW 37kDa) 是一种 Na+激活的胰蛋白酶样别构丝氨酸蛋白酶。它能够利用凝血酶识别序列对融合蛋白进行位点特异性切割，并可用于消化 GST 标记的蛋白。
T7625	TRAP-6 PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)	Protease-activated Receptor	GPCR/G Protein
	TRAP-6 (Thrombin Receptor Activator Peptide 6) 是一种多肽片段，是选择性的蛋白酶激活受体 1 (PAR1) 激动剂，通过凝血酶受体激活人血小板。
T7496	Thrombin Receptor Activator for Peptide 5 (TRAP-5) Thrombin Receptor Activator for Peptide	Protease-activated Receptor	GPCR/G Protein
	Thrombin Receptor Activator for Peptide 5 (TRAP-5) 也称为凝血因子 II 受体 (1-5) 或蛋白酶激活受体 1 (1-5)，用于研究冠心病 (CHD)。
T17091	Thrombin Inhibitor 2	Others	Others
	Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor. Thrombin Inhibitor 2 has antithrombotic activity.
T36553	Thrombin Receptor Peptide Ligand (trifluoroacetate salt)
	Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating peptide in vitro when used at a concentration of 32 μM but does not affect platelet aggregation induced by ADP or collagen. It also inhibits thrombin- and TRAP-induced proliferation of vascular smooth muscle cells (VSMCs). Thrombin receptor peptide ligand (100 μmol/kg bolus, i.v...
T10081	Thrombin inhibitor 1	Thrombin	Proteases/Proteasome
	Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).
T36777	Thrombin Receptor Agonist Peptide (trifluoroacetate salt)
	Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. It induces aggregation of washed platelets as well as platelets in citrated and hirudin plasma. TRAP-14 (100 μM) increases the cytosolic calcium concentration in isolated guinea pig pulmonary smooth muscle cells 5-fold over baseline. It increases pulmonary arterial pressure in isolated guinea pig lung when used at a concentration of 1 μM, which is comparable to the effect induced by 10 nM α...
T72448	Thrombin inhibitor 6
	Thrombin inhibitor6为高效的凝血酶抑制剂，IC50值为1 nM，表现出显著的抗凝作用。
TP2234	coagulation factor II (thrombin) B chain fragment [Homo sapiens]	Others	Others
	Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a serine protease that converts soluble
T80512	Thrombin receptor peptide ligand	Thrombin	Proteases/Proteasome
	Thrombin receptor peptide ligand为凝血酶受体的一种拮抗肽，用于抗血栓治疗。
T3757	NQ301	Thrombin; Platelet aggregation	Others; Proteases/Proteasome
	NQ301 是一种抗血栓剂，能够抑制胶原蛋白激发的兔血小板聚集，IC50=10 mg/mL。
T7137	I-191	Protease-activated Receptor	GPCR/G Protein
	I-191 是选择性有效的蛋白酶激活受体 2 拮抗剂。
T1986	Atopaxar E5555,ER-172594-00	Protease-activated Receptor	GPCR/G Protein
	Atopaxar (E5555) 是一种高效、可口服的，选择性的，可逆的凝血酶受体蛋白酶激活受体-1 (PAR-1) 拮抗剂。它是一种抗血小板剂，能干扰血小板信号，可用于动脉粥样硬化血栓性疾病的研究。
T12870	SCH79797 dihydrochloride	Apoptosis; Others; Protease-activated Receptor	Apoptosis; GPCR/G Protein; Others
	SCH79797 dihydrochloride 是一种有效的特异性蛋白酶激活受体 1 (PAR1) 拮抗剂，IC50 为 70 nM，Ki 为 35 nM。SCH79797 dihydrochloride 具有抗增殖和促凋亡作用。
TQ0012	AZ3451	Protease-activated Receptor	GPCR/G Protein
	AZ3451 是蛋白酶激活受体 2 的变构拮抗剂，IC50值为 23 nM。
T6594	MNS	Syk; Src; p97	Angiogenesis; Tyrosine Kinase/Adaptors; Ubiquitination
	MNS 是一种酪氨酸激酶抑制剂和广谱抗血小板药物，是一种 β-硝基苯乙烯衍生物。它完全抑制 U46619 (IC50:2.1 μM)、ADP (IC50:4.1 μM)、花生四烯酸 (IC50:5.8 μM)、胶原 (IC50:7.0 μM)和凝血酶 (IC50:12.7 μM)诱导的血小板聚集，并抑制 Src (IC50:27.3 μM)、Syk (IC50:2.8 μM) 和 FAK (IC50:97.6 μM)。
T2370	AC-55541 AOB2796	Proteasome; Protease-activated Receptor	GPCR/G Protein; Proteases/Proteasome; Ubiquitination
	AC-55541 (AOB2796) 是高选择性的蛋白酶激活受体 2(PAR2)激动剂，pEC50为6.7。它在 PI 水解测定和 Ca2+动态测定中的pEC50值为 5.9 和 6.6，在体内表现出伤害感受器活性。
TP1046	SLIGRL-NH2 Protease-Activated Receptor-2 Activating Peptide	Protease-activated Receptor	GPCR/G Protein
	SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) 为一种蛋白酶激活受体-2 (PAR-2) 激动剂，具有诱导非组胺能性瘙痒的功能。
T6295	Dabigatran BIBR 953,BIBR 953ZW,达比加群	Thrombin	Proteases/Proteasome
	Dabigatran (BIBR 953ZW) 是一种口服抗凝剂，是一种可逆的，竞争性的直接凝血酶 (thrombin) 抑制剂，Ki=4.5 nM。它也抑制凝血酶诱导的血小板聚集 (IC50=10 nM)。
T22246	Argatroban Monohydrate 阿加曲班一水合物,阿加曲班	Thrombin	Proteases/Proteasome
	Argatroban Monohydrate 是一种 thrombin 选择性抑制剂。
T6370	AEBSF hydrochloride AEBSF HCl,Pefabloc SC	Thrombin; Serine Protease; Influenza Virus	Microbiology/Virology; Proteases/Proteasome
	AEBSF hydrochloride (Pefabloc SC) 是一种丝氨酸蛋白酶的不可逆抑制剂。
T5519	Bivalirudin BG-8967,比伐卢定,Hirulog-1	Thrombin	Proteases/Proteasome
	Bivalirudin (BG-8967) 是一种直接凝血酶(thrombin)抑制剂，是一种肽类抗凝剂，可在侵入性心脏病，特别是在经皮冠状动脉介入中用于抗凝。
T7013	Vorapaxar SCH 530348,MK-5348,沃拉帕沙	Protease-activated Receptor	GPCR/G Protein
	Vorapaxar (MK-5348) 是抗血小板药物，是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki 值为 8.1 nM。它靠剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集。
T0389	Dabigatran etexilate 达比加群酯,BIBR 1048	Thrombin	Proteases/Proteasome
	Dabigatran etexilate (BIBR 1048) 是一种 Dabigatran 前药，具有口服活性。它具有抗凝作用，能够预防心房颤动引起的静脉血栓栓塞和中风。
T1893	Parmodulin 2 ML 161	Protease-activated Receptor	GPCR/G Protein
	Parmodulin 2 (ML 161) 是一种蛋白酶激活受体 1(PAR1) 变构抑制剂，IC50为 0.26 μM。它是蛋白酶激活受体 1 (PAR1) 介导的血小板活化的抑制剂，可以抑制体外血小板聚集和体内血小板血栓形成。
T0155	Argatroban MCI-9038,阿加曲班,MD-805,Argipidine	Thrombin	Proteases/Proteasome
	Argatroban (MCI-9038) 是一种选择性的凝血酶抑制剂。
T22323	Enoxaparin sodium	Thrombin	Proteases/Proteasome
	Enoxaparin sodium 是一种低分子量肝素 (LMWH)，已获得美国 FDA 批准，可用于医疗管理的 ST 段心肌梗死 (STEMI) 或 STEMI 及随后的经皮冠状动脉介入治疗 (PCI) 患者。它与抗凝血酶结合并增强其作用，并抑制凝血因子 XIa、IXa、Xa 和 IIa（凝血酶），从而防止血栓形成。
T5133	Dabigatran Etexilate Mesylate 甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate	Thrombin	Proteases/Proteasome
	Dabigatran Etexilate Mesylate (BIBR 1048MS) 是一种口服具有活性的 Dabigatran 前药，具有抗凝作用，能够预防心房颤动引起的静脉血栓栓塞和中风。
T8917	PAR-2-IN-1 IUN76750,8-(叔丁基)-6-氯咪唑并[1,2-B]吡啶-2-羧酸甲酯	Protease-activated Receptor	GPCR/G Protein
	PAR-2-IN-1 (IUN76750) 是一种 PAR-2 信号通路抑制剂，具有抗炎和抗癌作用。
T17265	Ximelagatran EXANTA,H 376-95,H37695,希美加群,H 376/95,H-37695,H 37695	Thrombin	Proteases/Proteasome
	Ximelagatran (H 376-95) 是一种口服活性凝血酶抑制剂，可选择性的、竞争性的抑制游离和凝块结合的凝血酶。它是一种抗凝药物，具有快速起效的抗凝作用，可预测的，剂量依赖性的药代动力学和药效学。
T3098	Vorapaxar sulfate SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙	Protease-activated Receptor	GPCR/G Protein
	Vorapaxar sulfate (Zontivity) 是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki 值为 8.1 nM。它剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集，是抗血小板药物。
TP1065	PAR-4 Agonist Peptide, amide TFA PAR-4-AP (TFA),AY-NH2 (TFA)	Protease-activated Receptor	GPCR/G Protein
	PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)) 是一种蛋白酶激活受体 4 (PAR-4) 激动剂，对 PAR-1 或 PAR-2 均无影响，其作用可被 PAR-4 拮抗剂阻断。
T7513	Protease-Activated Receptor-2, amide 蛋白酶活化的受体-2，酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-2, amide (SLIGKV-NH2) 是 PAR2 的激动剂，IC50为 10.4 M。
T1986L	Atopaxar Hydrobromide	Protease-activated Receptor	GPCR/G Protein
	Atopaxar hydrobromide 是可口服的，高效选择性的可逆凝血酶受体蛋白酶激活受体-1 拮抗剂。它是一种抗血小板剂，能干扰血小板信号，用于动脉粥样硬化血栓性疾病的研究。
T10951	Dabigatran ethyl ester hydrochloride N-[[2-[[[4-(氨基亚氨甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-(2-吡啶基)-BETA-丙氨酸乙酯盐酸盐	Others; Thrombin	Others; Proteases/Proteasome
	Dabigatran ethyl ester hydrochloride 是一种核糖基二氢烟酰胺脱氢酶抑制剂，IC50=0.8 μM，也是一种凝血酶的抑制剂。
T2368	Edoxaban Tosylate Monohydrate DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban,依度沙班对甲苯磺酸盐一水化合物	Factor Xa; Thrombin	Metabolism; Proteases/Proteasome
	Edoxaban Tosylate Monohydrate (DU-176b tosylate Monohydrate) 是口服具有活力的 factor Xa 选择性抑制剂。它是一种抗凝剂，可用于预防中风，是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂，对 FXa 的选择性超过 10000 倍。它具有抗血栓形成的特性，可用于血栓栓塞性疾病的研究。
T4186	AC-264613 AC264613	Protease-activated Receptor	GPCR/G Protein
	AC-264613 是一种选择性蛋白酶激活受体 (PAR-2) 激动剂，pEC50为 7.5。
T40711	H-D-Phe-Pip-Arg-pNA dihydrochloride S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride	Others	Others
	H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, H-D-Phe-Pip-Arg-pNA dihydrochloride is employed for the quantification of antithrombin-heparin cofactor (AT-III). The AT-III assay utilizing this substrate is characterized by its sensitivity, accuracy, and ease of implementation.
T7573	TFLLR-NH2 TFLLR-NH2(2TFA)	Protease-activated Receptor	GPCR/G Protein
	TFLLR-NH2 是选择性的一种PAR1激动剂，EC50值为1.9 μM。
T7380	Protease-Activated Receptor-4 蛋白酶活化的受体-4	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-4 是蛋白酶激活受体 4 激动剂，具有抗血小板治疗。
T7623	PAR-4 Agonist Peptide, amide AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP	Protease-activated Receptor	GPCR/G Protein
	PAR-4 Agonist Peptide, amide (AY-NH2) 是蛋白酶激活受体 4 (PAR-4) 的激动剂，对 PAR-1 或 PAR-2 均无影响，其作用可被 PAR-4 拮抗剂阻断。
T22676	Prothrombin (474-477) [Mus musculus]	Others	Others
	Prothrombin (coagulation factor II) is produced in the liver and is post-translationally modified in a vitamin K-dependent reaction that converts ten glutamic acids on prothrombin into gamma-carboxyglutamic acid. Prothrombin is proteolytically cleaved to
T8362	Benzamidine hydrochloride Benzamidine HCl,苄脒盐酸盐	Serine/threonin kinase; Serine Protease	Cell Cycle/Checkpoint; Metabolism; Proteases/Proteasome
	Benzamidine hydrochloride (Benzamidine HCl) 是可逆的胰蛋白酶样丝氨酸蛋白酶 (trypsin-like serine proteases) 竞争性抑制剂，对 uPA、类胰蛋白酶、胰蛋白酶和 Xa 因子作用的Ki 分别为 97 µM、20 µM、21 µM 和 110 µM。
T9892	JAMM protein inhibitor 2 Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-	Others	Others
	JAMM protein inhibitor 2 (Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-) 是 JAMM 蛋白酶的抑制剂，可用于抗癌的研究。对thrombin、Rpn11 和 MMP2 的 IC50 分别为 10 μM、46 μM 和 89 μM。
T25364L	Efegatran sulfate LY294468 sulfate,GYKI-14766 sulfate,LY 294468 sulfate,LY-294468 sulfate	Thrombin	Proteases/Proteasome
	Efegatran sulfate (LY294468 sulfate) 是一种有效的凝血酶抑制剂，可用于治疗血栓类疾病。
T37034	H-Gly-Arg-pNA dihydrochloride H-Gly-Arg-Pna 2HCl
	H-Gly-Arg-pNA dihydrochloride (H-Gly-Arg-Pna 2HCl) 属于多肽类，可与1,2凝血酶结合，可通过 405 纳米波长的比色检测进行定量，作为凝血酶活性的测量指标。
TP1143L	Fibrinopeptide A, human acetate Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate	Others	Others
	Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate)(25422-31-5 free base) 是一种 16 个残基的短多肽，由凝血酶从纤维蛋白原上切割下来。纤维蛋白肽 A (FPA) 由纤维蛋白原蛋白的 N 末端 Aα 区域在被凝血酶切割后产生。
T36951	N-(p-Tosyl)-GPR-pNA acetate	Others	Others
	N-(p-Tosyl)-GPR-pNA acetate 是凝血酶的比色底物，可作为凝血酶活性的量度。

化合物

Thrombin inhibitor 5

Cat.No: T9845

Thrombin Receptor Activator for Peptide

Cat.No: T7674

Target: Protease-activated Receptor

Thrombin (MW 37kDa)

Cat.No: T19580

Synonym: 凝血酶,Thrombin

Target: Thrombin

Cat.No: T7625

Synonym: PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)

Target: Protease-activated Receptor

Thrombin Receptor Activator for Peptide 5 (TRAP-5)

Cat.No: T7496

Synonym: Thrombin Receptor Activator for Peptide

Target: Protease-activated Receptor

Thrombin Inhibitor 2

Cat.No: T17091

Target: Others

Thrombin Receptor Peptide Ligand (trifluoroacetate salt)

Cat.No: T36553

Thrombin inhibitor 1

Cat.No: T10081

Target: Thrombin

Thrombin Receptor Agonist Peptide (trifluoroacetate salt)

Cat.No: T36777

Thrombin inhibitor 6

Cat.No: T72448

coagulation factor II (thrombin) B chain fragment [Homo sapiens]

Cat.No: TP2234

Target: Others

Thrombin receptor peptide ligand

Cat.No: T80512

Target: Thrombin

Cat.No: T3757

Target: Thrombin, Platelet aggregation

Cat.No: T7137

Target: Protease-activated Receptor

Cat.No: T1986

Synonym: E5555,ER-172594-00

Target: Protease-activated Receptor

SCH79797 dihydrochloride

Cat.No: T12870

Target: Apoptosis, Others, Protease-activated Receptor

Cat.No: TQ0012

Target: Protease-activated Receptor

Cat.No: T6594

Target: Syk, Src, p97

Cat.No: T2370

Synonym: AOB2796

Target: Proteasome, Protease-activated Receptor

Cat.No: TP1046

Synonym: Protease-Activated Receptor-2 Activating Peptide

Target: Protease-activated Receptor

Cat.No: T6295

Synonym: BIBR 953,BIBR 953ZW,达比加群

Target: Thrombin

Argatroban Monohydrate

Cat.No: T22246

Synonym: 阿加曲班一水合物,阿加曲班

Target: Thrombin

AEBSF hydrochloride

Cat.No: T6370

Synonym: AEBSF HCl,Pefabloc SC

Target: Thrombin, Serine Protease, Influenza Virus

Cat.No: T5519

Synonym: BG-8967,比伐卢定,Hirulog-1

Target: Thrombin

Cat.No: T7013

Synonym: SCH 530348,MK-5348,沃拉帕沙

Target: Protease-activated Receptor

Dabigatran etexilate

Cat.No: T0389

Synonym: 达比加群酯,BIBR 1048

Target: Thrombin

Cat.No: T1893

Synonym: ML 161

Target: Protease-activated Receptor

Cat.No: T0155

Synonym: MCI-9038,阿加曲班,MD-805,Argipidine

Target: Thrombin

Enoxaparin sodium

Cat.No: T22323

Target: Thrombin

Dabigatran Etexilate Mesylate

Cat.No: T5133

Synonym: 甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate

Target: Thrombin

Cat.No: T8917

Synonym: IUN76750,8-(叔丁基)-6-氯咪唑并[1,2-B]吡啶-2-羧酸甲酯

Target: Protease-activated Receptor

Cat.No: T17265

Synonym: EXANTA,H 376-95,H37695,希美加群,H 376/95,H-37695,H 37695

Target: Thrombin

Vorapaxar sulfate

Cat.No: T3098

Synonym: SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙

Target: Protease-activated Receptor

PAR-4 Agonist Peptide, amide TFA

Cat.No: TP1065

Synonym: PAR-4-AP (TFA),AY-NH2 (TFA)

Target: Protease-activated Receptor

Protease-Activated Receptor-2, amide

Cat.No: T7513

Synonym: 蛋白酶活化的受体-2，酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2

Target: Protease-activated Receptor

Atopaxar Hydrobromide

Cat.No: T1986L

Target: Protease-activated Receptor

Dabigatran ethyl ester hydrochloride

Cat.No: T10951

Synonym: N-[[2-[[[4-(氨基亚氨甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-(2-吡啶基)-BETA-丙氨酸乙酯盐酸盐

Target: Others, Thrombin

Edoxaban Tosylate Monohydrate

Cat.No: T2368

Synonym: DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban,依度沙班对甲苯磺酸盐一水化合物

Target: Factor Xa, Thrombin

Cat.No: T4186

Synonym: AC264613

Target: Protease-activated Receptor

H-D-Phe-Pip-Arg-pNA dihydrochloride

Cat.No: T40711

Synonym: S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride

Target: Others

Cat.No: T7573

Synonym: TFLLR-NH2(2TFA)

Target: Protease-activated Receptor

Protease-Activated Receptor-4

Cat.No: T7380

Synonym: 蛋白酶活化的受体-4

Target: Protease-activated Receptor

PAR-4 Agonist Peptide, amide

Cat.No: T7623

Synonym: AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP

Target: Protease-activated Receptor

Prothrombin (474-477) [Mus musculus]

Cat.No: T22676

Target: Others

Benzamidine hydrochloride

Cat.No: T8362

Synonym: Benzamidine HCl,苄脒盐酸盐

Target: Serine/threonin kinase, Serine Protease

JAMM protein inhibitor 2

Cat.No: T9892

Synonym: Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-

Target: Others

Efegatran sulfate

Cat.No: T25364L

Synonym: LY294468 sulfate,GYKI-14766 sulfate,LY 294468 sulfate,LY-294468 sulfate

Target: Thrombin

H-Gly-Arg-pNA dihydrochloride

Cat.No: T37034

Synonym: H-Gly-Arg-Pna 2HCl

Fibrinopeptide A, human acetate

Cat.No: TP1143L

Synonym: Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate

Target: Others

N-(p-Tosyl)-GPR-pNA acetate

Cat.No: T36951

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3839	Cycloolivil Isoolivil,环橄榄树脂素	Free radical scavengers; Others; Platelet aggregation	Others; oxidation-reduction
	Cycloolivil (Isoolivil) 是一种天然多酚化合物，在橄榄树中具有显着的自由基清除活性。 Cycloolivil 具有抗氧化活性，它可以预防与血小板过度聚集相关的血栓并发症，是开发抗聚集治疗策略的基础。
T3781	Jujuboside B 酸枣仁皂苷 B,酸枣仁皂苷B	Others	Others
	Jujuboside B 是一种提取自Zizyphus jujuba 中的活性成分，对血小板聚集具有抑制作用。
T3793	(20R)-Ginsenoside Rh1 20(R)-Ginsenoside Rh1,人参皂苷 R-RH1,人参皂苷R-RH1	Others	Others
	(20R)-Ginsenoside Rh1 (20(R)-Ginsenoside Rh1) 是 Ginsenoside Rh1 的 R 型异构体，分离自 Panax Ginseng 中，能够阻碍凝血酶诱导的纤维蛋白原向纤维蛋白的转化。
TN1054	Loureirin C 龙血素C,龙血素 C	Others	Others
	Loureirin C 在体外能有效抑制凝血酶的活性。它具有抗菌，抗痉挛，抗炎，止痛，抗糖尿病和抗肿瘤作用。
T3S0601	Buddlejasaponin IVb 醉鱼草皂苷IVb,Saikosaponin 1b	Others	Others
	Buddlejasaponin IVb (Saikosaponin 1b) 是一种三萜皂苷，从Clinopodium chinense (Benth.) O. Kuntze 中分离得到，能够缩短凝血时间，具有止血作用。
TN3831	(-)-Denudatin B Denudatin B	ATPase; Potassium Channel; Calcium Channel; PAFR	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
	(-)-Denudatin B (Denudatin B) 源自 Magnolia fargesii。 (-)-Denudatin B 通过抑制胶原蛋白和凝血酶诱导的磷酸肌醇分解，在高浓度下具有非特异性抗血小板作用。
T5S0896	Loureirin A 龙血素 A,龙血素A	Akt; PI3K	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Loureirin A 是一种黄酮类物质，从龙血树中分离得到，能够降低Akt 的磷酸化，具有抗血小板聚集作用。
T5S2358	Dehydrocorydaline Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine	BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
	Dehydrocorydaline (13-Methylpalmatine) 是一种生物碱。它调节Bax，Bcl-2蛋白表达，激活caspase-7，caspase-8，并使PARP 失活。它能增强p38 MAPK 活化，具有抗炎、抗癌等功效。它具有强大的抗疟疾作用，并具低细胞毒性。
TN4917	Rosenonolactone	Others	Others
	Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin.
T36532	SCH 38519
	SCH 38519 is an isochromanequinone fungal metabolite originally isolated from Thermomonospora. It inhibits aggregation induced by thrombin , as well as inhibits serotonin secretion in human platelets (IC50s = 68 and 61 μg/ml, respectively). It inhibits the growth of various Gram-negative and Gram-positive bacteria (mean MICs = 122.1 and 0.92 μg/ml, respectively).
TN4860	Pueroside B	COX; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience
	Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A receptor (HMGR), cyclooxygenase-2 (COX2
TN6014	Norcepharadione B 鱼腥草
	Norcepharadione B shows good inhibitory activity against the replication of HSV-1, it also shows antimalarial activity with EC50 values of 7.5mug/ml. Norcepharadione B exhibits significant cytotoxicity against five human tumor cell lines (A-549, SK-OV-3,

天然产物

Cat.No: T3839

Synonym: Isoolivil,环橄榄树脂素

Target: Free radical scavengers, Others, Platelet aggregation

Cat.No: T3781

Synonym: 酸枣仁皂苷 B,酸枣仁皂苷B

Target: Others

(20R)-Ginsenoside Rh1

Cat.No: T3793

Synonym: 20(R)-Ginsenoside Rh1,人参皂苷 R-RH1,人参皂苷R-RH1

Target: Others

Cat.No: TN1054

Synonym: 龙血素C,龙血素 C

Target: Others

Buddlejasaponin IVb

Cat.No: T3S0601

Synonym: 醉鱼草皂苷IVb,Saikosaponin 1b

Target: Others

(-)-Denudatin B

Cat.No: TN3831

Synonym: Denudatin B

Target: ATPase, Potassium Channel, Calcium Channel, PAFR

Cat.No: T5S0896

Synonym: 龙血素 A,龙血素A

Target: Akt, PI3K

Dehydrocorydaline

Cat.No: T5S2358

Synonym: Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Rosenonolactone

Cat.No: TN4917

Target: Others

Cat.No: T36532

Cat.No: TN4860

Target: COX, PPAR

Norcepharadione B

Cat.No: TN6014

Synonym: 鱼腥草

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