152
92
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19916 |
TRIM
1-(2-Trifluoromethylphenyl)imidazole,1-(2-三氟甲基苯基)咪唑 |
NOS | Immunology/Inflammation |
TRIM (1-(2-Trifluoromethylphenyl)imidazole) 是一氧化氮合酶抑制剂。它在体外能够抑制小鼠小脑 nNOS (IC50:28.2 µM),以及大鼠肺 iNOS (IC50:27.0 µM)。它拥有抗焦虑以及抗抑郁的能力。 | |||
T74271 | TRIM24/BRPF1-IN-2 | ||
TRIM24/BRPF1-IN-2 (compound 20l) 是一种有效的 TRIM24/BRPF1双重抑制剂,IC50值分别为 0.98 和 1.16 μM。 TRIM24/BRPF1-IN-2 显示出 TRIM24/BRPF1 溴结构域结合亲和力。 TRIM24/BRPF1-IN-2 可用于前列腺癌研究。 | |||
T22445 |
Trimethyloctadecylammonium bromide
|
Dynamin | Cytoskeletal Signaling |
Trimethyloctadecylammonium bromide 是 Dynamin I 的抑制剂 (IC50 : 1.9 μM),也抑制 Dynamin Ⅱ。 | |||
T67906 |
Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate)
|
||
Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate)是一种化合物,是复方他汀类磷酸衍生物。 | |||
T13564L2 |
AZ7550 trimesylate salt
AZ7550 Mesylate,AZ7550 trimesylate salt (1421373-99-0 free base) |
MLK | MAPK |
AZ7550 trimesylate salt (AZ7550 Mesylate) 是奥希替尼的活性代谢产物,AZ7550 trimesylate salt 抑制 IGF1R 活性,可用于研究非小细胞肺癌。 | |||
T61148 |
Flutrimazole
|
Antifungal | Microbiology/Virology |
Flutrimazole是一种具有双重作用的咪唑类抗真菌化合物,展现出抗炎和抗真菌的属性。值得注意的是,flutrimazole的经皮渗透性有限,这使其在治疗伴有炎症的真菌感染的局部应用中特别有优势。 | |||
T1197 |
Trimebutine maleate
Debridat,Polibutin,马来酸曲美布汀 |
Calcium Channel; Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Trimebutine maleate (Polibutin) 是一种外周 μ、δ 和 kappa 阿片受体激动剂,用作治疗慢性和急性腹痛的解痉药物。 | |||
T0240 |
Trimetozine
Sedoxazine,Trioxazin,三甲氧啉 |
Others | Others |
Trimetozine (Sedoxazine) 是一种镇静剂,自 1959 年以来一直在欧洲上市。它具有温和的镇静作用,已用于治疗焦虑症。 | |||
T22981 |
Tetradecyltrimethylammonium bromide
MitMAB,Cetrimide,tetradecyl trimethyl ammonium bromide,十四烷基三甲基溴化铵 |
Dynamin | Cytoskeletal Signaling |
Tetradecyltrimethylammonium bromide (MitMAB) 是一种具有不对称结构的阳离子表面活性剂,是一种有机结构单元。 | |||
T0546 |
Trimethylacetic anhydride
Pivalic anhydride,三甲基乙酸酐 |
Others | Others |
Trimethylacetic anhydride (Pivalic anhydride) 用作医药中间体。 | |||
T18885 |
3,6-Dichlorotrimellitic acid
|
Others | Others |
3,6-Dichlorotrimellitic acid 是一种制备多种二氯化荧光素和罗丹明 (如 TET 和 HEX) 的关键性前体试剂,这些氯化荧光素和罗丹明普遍用作寡核苷酸及 DNA 测序的标记。 | |||
T9128 |
N-Desmethyltrimipramine
|
Others | Others |
N-Desmethyltrimipramine 是一种生化物质。 | |||
T7528 |
3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate
|
Others | Others |
3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate 是一种有用的研究化合物,适用于许多研究应用,包括化学领域和生命科学领域等。 | |||
T5009 |
Trimethobenzamide hydrochloride
盐酸三甲氧苯酰胺,Ro 2-9578,Tribenzagan Hydrochloride |
Dopamine Receptor; Influenza Virus | GPCR/G Protein; Microbiology/Virology; Neuroscience |
Trimethobenzamide hydrochloride (Ro 2-9578) 是一种多巴胺D2受体阻断剂,是一种止吐剂,用于预防恶心和呕吐。 | |||
T0918 |
Trimebutine
曲美布汀,Mebutin |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Trimebutine (Mebutin) 是阿片受体激动剂,有抗毒蕈碱活性。它是解痉剂,可调节肠道和结肠运动,并通过抗毒蕈碱和弱μ-阿片受体激动剂作用缓解腹痛。 | |||
T0506 |
Clotrimazole
克霉唑,BAY b 5097,FB 5097 |
Antibacterial; Antibiotic; Antifection; Autophagy; Antifungal | Autophagy; Microbiology/Virology |
Clotrimazole (FB 5097) 是咪唑衍生物,有抗真菌和抗菌活性,是 P450抑制剂。 | |||
T18886 |
3,6-Dichlorotrimellitic anhydride
|
Others | Others |
3,6-Dichlorotrimellitic anhydride 是一种能够制备多种二氯化荧光素和罗丹明 (如TET 和HEX) 的关键性前体试剂,其中氯化荧光素和罗丹明普遍用于寡核苷酸和DNA 测序的标记。 | |||
T1357 |
TriMetazidine EP IMpurity-D
|
Others | Others |
TriMetazidine EP IMpurity-D 是合成 TriMetazidine 的起始原料,是合成多种化合物的中间体。 | |||
T9876 |
Piperazine, 1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-
|
Others | Others |
Piperazine,1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-是一种哌嗪衍生物,显示出抗 SARS-CoV-2活性。 | |||
T27413 |
Trimebutine CTB salt
GIC1001 |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Trimebutine CTB salt (GIC-1001) 是一种阿片受体激动剂,可用于研究疼痛。 | |||
T0497 |
Cetrimonium bromide
Lauroseptol,Cetyltrimethylammonium Bromide,西曲溴铵,CTAB |
Antibiotic | Microbiology/Virology |
Cetrimonium bromide (Lauroseptol) 是局部消毒剂 Cetrimide 的组成部分之一,是一种阳离子季胺盐表面活性剂。 | |||
T0527 |
2,3,4-Trimethoxybenzaldehyde
Benzaldehyde,三甲氧基苯甲醛,Trimethoxybenzaldehyde |
Others | Others |
2,3,4-Trimethoxybenzaldehyde (Trimethoxybenzaldehyde) 用作医药中间体。 | |||
T22214 |
1,5,5-Trimethylhydantoin
1,5,5-三甲基海因,TMH |
Others | Others |
1,5,5-Trimethylhydantoin (TMH) 是非同位素内标化合物的一种。 | |||
T67732 |
Potassium trimethylsilanolate
Trimethylsiloxypotassium |
Others | Others |
Potassium trimethylsilanolate 是一种催化剂。Potassium trimethylsilanolate 通过(TMSOK)通过硼酸途径促进 Suzuki Miyaura 反应。 | |||
T64386 |
2,3,5-Trimethylphenol
Isopseudocumenol |
Others | Others |
2,3,5-Trimethylphenol (Isopseudocumenol) 是一种抗增殖化合物,对T. pyriformisp 的pGI50= 0.36。 | |||
T0988 |
Trimetazidine dihydrochloride
盐酸曲美他嗪,Yoshimilon,Kyurinett,Vastarel F |
Autophagy; Fatty Acid Synthase | Autophagy; Metabolism |
Trimetazidine dihydrochloride (Vastarel F) 是细胞保护性抗缺血剂,也用作缺血性心脏病或心绞痛的血管扩张剂,具有抗氧化,抗炎,抗伤害和胃保护作用。它可通过抑制脂肪酸代谢提高心肌葡萄糖利用率。 | |||
T0283 |
Trimethadione
三甲双酮,3,5,5,-Trimethyloxazolidine-2,4-dione |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) 是恶唑烷二酮类抗惊厥剂,也是一种 T 型钙通道阻滞剂,具有抗痛觉过敏作用,可用于研究失神发作。 | |||
T9944 |
3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
|
MRP | Immunology/Inflammation |
3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1). | |||
T15178 |
dTRIM24
|
Others | Others |
dTRIM24 是一种基于 PROTAC 技术的选择性双功能 TRIM24 降解剂,由von Hippel-Lindau 和TRIM24 两者配体构成。 | |||
T66135 | Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene][[5-[(dimethylamino)sulfonyl]-2-(1-methylethoxy-O)phenyl]methylene-C]ruthenium(II) | ||
Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene][[5-[(dimethylamino)sulfonyl]-2-(1-methylethoxy-O)phenyl]methylene-C]ruthenium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T66135。 | |||
T40435 |
Chlorin e6 trimethyl ester
二氢卟吩 e6 三甲酯 |
||
Chlorin e6 trimethyl ester, a derivative of methyl pheophorbide-a, is an effective photosensitizer for photodynamic therapy (PDT). | |||
T21364 |
Trimipramine
Stangyl,Rhotrimine,Surmontil |
||
Trimipramine is an antidepressant with an anxiety-reducing sedative component to its action. | |||
T68811 | Trimetaphan camsilate | ||
Trimetaphan camsilate is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous system. It acts as a non-depolarizing competitive antagonist at the nicotinic acetylcholine receptor, is short-acting, and is given intravenously. | |||
T67179 | N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (chloride) | ||
N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (chloride) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67179。 | |||
T123947 | 3',5-Dihydroxy-4',6,7-trimethoxyflavanone | ||
3',5-Dihydroxy-4',6,7-trimethoxyflavanone 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T123947。 | |||
T64625 | 2-(5-(3-(5-Carboxypentyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1,3-trimethyl-1H-benzo[e]indol-3-ium | ||
2-(5-(3-(5-Carboxypentyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1,3-trimethyl-1H-benzo[e]indol-3-ium 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64625。 | |||
T9539 | (E)-1,7,7-trimethyl-3-((3-(trifluoromethyl)phenyl)imino)bicyclo【2.2.1】heptan-2-one | ||
(E)-1,7,7-trimethyl-3-((3-(trifluoromethyl)phenyl)imino)bicyclo【2.2.1】heptan-2-one 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T9539。 | |||
T64669 | (R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-7,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | ||
(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-7,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64669。 | |||
T25101 |
Antrimycin
Antrimycin A,Cirratiomycin B |
||
Antrimycin is an antibiotic. | |||
T66182 | 2,3,4,6-Tetra-O-(trimethylsilyl)-D-glucono-delta-lactone | ||
2,3,4,6-Tetra-O-(trimethylsilyl)-D-glucono-delta-lactone 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66182,CAS号为 32384-65-9。 | |||
T17164 |
Trimetrexate
三甲曲沙,CI-898 |
Others | Others |
Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase. | |||
T71326 |
1,3,7-Trimethyluric Acid-d9
|
||
1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid and a metabolite of caffeine. It is formed from caffeine by the cytochrome P450 isoform CYP3A4. 1,3,7-Trimethyluric acid scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes. | |||
T74582 |
Trimipramine N-oxide
|
||
Trimipramine N-oxide 为三环抗抑郁药trimipramine的活性代谢物,其对人去甲肾上腺素单胺转运体(hNAT)、血清素(hSERT)、多巴胺(hDAT)以及人体有机阳离子转运蛋白(hOCT1与hOCT2)的IC50值分别为11.7、3.59、9.4、9.35及27.4 nM。因此,Trimipramine N-oxide在忧郁和焦虑研究中有应用价值。 | |||
T36610 |
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine
|
||
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities. It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM). CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis. It reverses hydrogen peroxide-induced release of malondialdehyde ... | |||
T34949 |
Trimethylolpropane caprate
UNII-X307CM75YF,Trimethylolpropane tridecanoate,Trimethylolpropane tricaprate |
||
Trimethylolpropane caprate has developmental toxicity in Sprague-Dawley rats. | |||
T66399 |
Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)bis(3-bromopyridine)ruthenium(II)
|
||
Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)bis(3-bromopyridine)ruthenium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66399,CAS号为 900169-53-1。 | |||
T29188 |
YM-543 trimethylamine
ASP 543,ASP-543,ASP543 |
||
YM-543, a sodium-glucose transporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes. | |||
T65559 |
Dodecyltrimethylammonium chloride
|
||
Dodecyltrimethylammonium chloride 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65559,CAS号为 112-00-5。 | |||
T74010 |
(Rac)-Mono(3,5,5-trimethylhexyl) phthalate
|
||
(Rac)-Mono(3,5,5-trimethylhexyl) phthalate 为常见邻苯二甲酸酯增塑剂的关键代谢物,具备免疫抑制功能。 | |||
T29335 |
2-Azabicyclo(3.2.1)octane, 3,4,4-trimethyl-
|
||
2-Azabicyclo(3.2.1)octane, 3,4,4-trimethyl- is a bioactive chemical. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4852 |
Trimyristin
Trimyristoylglycerol,Tritetradecanoin,三肉豆蔻酸甘油酯,Glyceryl trimyristate,甘油三肉豆蔻酸酯,1,2,3-Tritetradecanoylglycerol |
Phosphatase; Endogenous Metabolite; AChE | Metabolism; Neuroscience |
Trimyristin (Tritetradecanoin) 是一种 Myristica fragransHoutt 的有效成分,能够显著抑制乙酰胆碱酯酶 (AChE),酸性和碱性磷酸酶 (ACP/ALP) 特性。它对 AChE,ACP 和 ALP 的 IC50分别为 0.11、0.16 和 0.18 mM。 | |||
T0572 |
Methyl 3,4,5-trimethoxybenzoate
Methyl gallate trimethyl ether,Methyl EudesMate,3,4,5-Trimethoxybenzoic acid methyl ester,Methyl tri-O-methylgallate,甲氧苄啶杂质H,Trimethylgallic acid methyl ester |
Others | Others |
Methyl 3,4,5-trimethoxybenzoate (Methyl EudesMate) 是由 Gallic acid 为原料合成得到,常用于生产磺胺增效剂中间体、甲氧苄氨嘧啶 (TMP)以及许多其它药物。 | |||
T40607 |
2,4,6-Trimethylphenol
Mesitol |
Others | Others |
2,4,6-Trimethylphenol (Mesitol) 是一种与有机物 (3DOM*) 反应的探针化合物,可在水溶液中被单线态氧快速氧化。 | |||
T3330 |
trans-Trimethoxyresveratrol
trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
trans-Trimethoxyresveratrol (MR-3) 是一种 Resveratrol(RSV) 的衍生物,与Resveratrol(RSV)相比,它可能是一个更有效的抗炎、抗血管新生的化合物。 | |||
T19129 |
3-(3,4,5-Trimethoxyphenyl)propanoic acid
|
Endogenous Metabolite | Metabolism |
3-(3,4,5-Trimethoxyphenyl)propanoic acid 是Piper longum(长胡椒) 和Piper retrofractum(爪哇长胡椒) 的成分,存在于草药和香料中。 | |||
T2S2169 |
Naringenin trimethyl ether
柚皮素三甲醚,5,7,4'-Trimethoxyflavanone |
Others | Others |
Naringenin trimethyl ether (5,7,4'-Trimethoxyflavanone) 是四季米仔兰枝、叶的成分。它具有明显的杀螺作用,对 P. canaliculata 作用的 LC50值为 3.9 μg/ mL。 | |||
TN1817 |
Kaempferol 3,7,4'-trimethyl ether
莰非醇-3,7,4'-三甲醚,莰非醇三甲醚,Kaempferol 3,7,4'-trimethylether |
NO Synthase | Immunology/Inflammation |
Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) 是一种黄酮醇苷元,从 Siparuna gigantotepala 中分离得到,具有抗氧化作用。 | |||
T1153 |
Trimethoprim
NIH 204,BW 56-72,甲氧苄啶,NSC-106568 |
DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology |
Trimethoprim (NSC-106568) 是抑菌抗生素,也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性,可用于尿路感染,肺孢子菌肺炎和志贺氏菌病的研究。 | |||
T7989 |
Trimethyl phosphate
|
Others | Others |
Trimethyl phosphate 是一种有机磷化合物,是催化磷酸化化合物水解的酶的抑制剂,已被用作合成肽和其他蛋白质的反应物,用作合成有机和无机化合物的催化剂,以及用作合成药物的试剂。 | |||
TN7176 |
1,3,5-Trimethyl-1H-Pyrazole-4-Carboxylic Acid
MFCD00159648,1,3,5-trimethylpyrazole-4-carboxylic acid,trimethyl-1H-pyrazole-4-carboxylic acid,1,3,5-三甲基-1H-吡唑-4-甲酸 |
Others | Others |
1,3,5-Trimethyl-1H-Pyrazole-4-Carboxylic Acid (1,3,5-trimethylpyrazole-4-carboxylic acid) 是一种海洋来源的天然产物,存在于Cinachyrella sp.。 | |||
TN1995 |
5,7,8-Trimethoxyflavone
Norwogonin 5,7,8-trimethyl ether |
NO Synthase | Immunology/Inflammation |
5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) 是从穿心莲中提取的化合物,具有抗炎活性,对 NO 有抑制作用。 | |||
T4827 |
Trimethylammonium chloride
三甲胺盐酸盐,Trimethylamine hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
Trimethylammonium chloride (Trimethylamine hydrochloride) 是动植物分解的产物。它是造成鱼腥味的主要物质,通常与脏鱼、细菌性阴道感染和口臭有关。它也与服用大剂量胆碱有关。三甲胺尿是一种遗传性疾病,身体无法从食物中代谢三甲胺。食用富含胆碱的食物后,患者的汗液、尿液和呼吸中会出现特有的鱼腥味。三甲胺尿症是一种常染色体隐性遗传病,涉及三甲胺氧化酶缺乏症。三甲氨基尿症在罗德岛红鸡中也有发现,这种鸡产的蛋有腥味。尿液中的 Trimethylammonium chloride 是食用豆类的生物标志物。 | |||
TN1287 |
5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavone
5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavone,5,7,3'-三羟基-6,4',5'-三甲氧基黄酮 |
Others | Others |
5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavone 是一种甲基化黄酮类化合物,从 Artemisia frigida 中提取得到。 | |||
T9780 |
3,4, 5-trimethoxyphenylacetic acid
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Endogenous Metabolite | Metabolism |
3,4, 5-trimethoxyphenylacetic acid 是有机合成中常见的中间体,其主要用途是将其羧基转化为相应的用途。 | |||
T5554 |
1,3,5-Trimethoxybenzene
Phloroglucinol trimethyl ether,Sym-trimethoxybenzene,1,3,5-三甲氧基苯 |
Others | Others |
1,3,5-Trimethoxybenzene (Phloroglucinol trimethyl ether) 是一种中国玫瑰品种中的主要芳香化合物。它在三个连续的甲基化步骤中由间苯三酚(初始前体) 合成。它能够用于缓解紧张等。 | |||
T8250 |
2,6,6-Trimethyl-2,4-cycloheptadien-1-one
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Others | Others |
2,6,6-Trimethyl-2,4-cycloheptadien-1-one 是一种萜类化合物,存在于许多植物中,包括香菜、莳萝和芹菜。它是精油的重要成分,具有多种药用和药理特性。 | |||
TN7053 |
3',4',7-Trimethoxyquercetin
3,5-Dihydroxy-7,3',4'-trimethoxyflavone,Quercetin 3′,4′,7-trimethyl ether,3',4',7-三甲氧基槲皮素 |
Others | Others |
3',4',7-Trimethoxyquercetin (3,5-Dihydroxy-7,3',4'-trimethoxyflavone) 是一种多甲氧基黄酮,提取自黄芩,具有抗氧化作用。 | |||
T19792 |
1,3,7-Trimethyluric acid
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Others | Others |
1,3,7-Trimethyluric acid 是咖啡因的代谢产物。其与咖啡因的代谢比可以反映 CYP3A 活性的变化情况。 | |||
TN3016 |
4',6,7-Trimethoxyisoflavone
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MMP | Proteases/Proteasome |
4',6,7-Trimethoxyisoflavone 通过 NOX2 诱导促进伤口愈合,从而导致集体迁移和 MMP 活化。 | |||
T0632 |
3,4,5-Trimethoxybenzoic acid
Gallic acid trimethyl ether,Eudesmic acid,3,4,5-三甲氧基苯甲酸,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid,没食子酸三甲醚 |
Antioxidant | oxidation-reduction |
3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) 是一种苯甲酸衍生物,可用作医药和有机合成中的砌块。 | |||
T9599 |
3,4,5-Trimethoxybenzaldehyde
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Anti-infection; Antibacterial | Microbiology/Virology |
3,4,5-Trimethoxybenzaldehyde 是合成各种药物,特别是治疗细菌感染的甲氧苄啶的中间体,它有抗念珠菌功效并抑制粘附和生物膜。 | |||
TN7222 |
2',3',4'-Trimethoxyacetophenone
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2',3',4'-Trimethoxyacetophenone 是制备查耳酮化合物的原料,具有抗炎活性。 | |||
T4702 |
(3-Carboxypropyl)trimethylammonium chloride
γ-Butyrobetaine hydrochloride,(3-羧丙基)三甲基氯化铵,(3-Carboxypropyl)trimethylammonium chlor |
Endogenous Metabolite | Metabolism |
(3-Carboxypropyl)trimethylammonium chloride ((3-Carboxypropyl)trimethylammonium chlor) 一种血管病变性中间代谢物,是由肠道微生物代谢产生,这些微生物以红肉中的肉碱为食。 | |||
T5247 |
Trimethylamine N-oxide dihydrate
二水氧化三甲胺,TMANO Dihydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Trimethylamine N-oxide dihydrate (TMANO Dihydrate) 是内源性代谢产物的一种。 | |||
T7051 |
5,6,7-TRIMETHOXYFLAVONE
Baicalein Trimethyl Ether,黄岑素-5,6,7-三甲醚 |
p38 MAPK | MAPK |
5,6,7-Trimethoxyflavone 是从日本紫珠提取出的一种天然产物,是 p38-α MAPK 抑制剂,具有抗炎作用。 | |||
T41245 |
Trimethylamine N-oxide
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Reactive Oxygen Species; NOD-like Receptor (NLR); TGF-beta/Smad | Immunology/Inflammation; Metabolism; NF-κB; Stem Cells |
Trimethylamine N-oxide (TMAO) 是由胆碱、甜菜碱和肉碱通过肠道微生物代谢产生的一种无色氧化胺,积聚在海洋动物的组织中,可预防尿素对蛋白质的破坏作用。Trimethylamine N-oxide 通过激活 ROS/NLRP3 炎性体诱导炎症,可诱导纤维细胞的分化和心脏纤维化。 | |||
T1045 |
Trimipramine maleate
Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐 |
Dopamine Receptor; 5-HT Receptor; Antibacterial; Adrenergic Receptor; Norepinephrine; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Trimipramine maleate (Surmontil maleate) 是一种 5-HT 受体拮抗剂,对 5-HT1C、5-HT2和 5-HT1A 受体的 pKi 值分别为 6.39、8.10和 4.66。 | |||
Fr14500 |
2,3,5-Trimethylpyrazine
|
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Compound Fr14500 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 Fr14500,CAS号为 14667-55-1。 | |||
T8296 |
5,7,4'-Trimethoxyflavone
5,7,4'-三甲氧基黄酮,芹菜素三甲醚,4',5,7-三甲氧基黄酮,4',5,7-Trimethoxyflavone |
Apoptosis; PARP; Caspase | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome |
5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) 是从泰国著名的药用植物 Kaempferia parviflora 中分离出来的一种天然产物。它以浓度依赖性方式显著有效抑制 SNU-16 人胃癌细胞的增殖,诱导细胞凋亡。 | |||
TN2865 |
(E)-3,4,5-Trimethoxycinnamic acid
O-Methylsinapic acid,3,4,5-三甲氧基肉桂酸,3,4,5-Trimethoxy-trans-cinnamic acid,3,4,5-Trimethoxyphenylacrylic acid |
Others | Others |
(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) 是一种来自羌活根和根茎的天然产物。 | |||
T2983 |
3,4,5-Trimethoxycinnamic acid
3-(3,4,5-Trimethoxyphenyl)acrylic Acid,O-Methylsinapic acid,3,4,5-三甲氧基肉桂酸 |
GABA Receptor; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) 是从远志中分离得到的苯丙素类天然产物,可延长动物的睡眠时间,增强 GAD65 和 GABAA 受体 γ 亚基,具有抗应激作用。 | |||
TN2867 | 3,4,5-Trimethoxyphenyl-(6-O-galloyl)-O-beta-D-glucopyranoside | Antifection | Microbiology/Virology |
3,4,5-Trimethoxyphenyl-(6'-O-galloyl)-O-beta-D-glucopyranoside shows in vitro antiplasmodial activity. | |||
T83558 | (3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone | ||
(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone(化合物3)是从丹参(Salvia miltiorrhiza)根提取的棕榈酸盐。该化合物展现出抗癌活性,对于不同的人类癌症细胞系具有显著的抑制效果,其DC50值分别为:HeLa细胞系25.5 μg/mL、HepG2细胞系37.5 μg/mL以及OVCAR-3细胞系30.2 μg/mL。 | |||
T83470 |
10-Hydroxy-2,6,10-trimethyl-2,6,11-dodeca-4-one
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Hydroxy-2,6,10-trimethyl-2,6,11-dodeca-4-one为Solanaceae科植物中存在的天然产物。 | |||
TN4556 |
Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate
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Others | Others |
Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4556,CAS号为 20329-96-8。 | |||
T31324 |
Decane, 2,5,6-trimethyl-
2,5,6-Trimethyldecane |
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Decane, 2,5,6-trimethyl- is a biochemical. | |||
T83308 |
5,4'-Dihydroxy-3,4,3'-trimethoxybibenzyl
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5,4'-Dihydroxy-3,4,3'-trimethoxybibenzyl (compound 8) 是从漏斗石斛 (D. infundibulum) 中分离出的化合物。该化合物不具有对 α-葡萄糖苷酶和胰脂肪酶的抑制活性。 | |||
TN6377 |
2'-Hydroxy-3',4',6'-trimethoxychalcone
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2'-Hydroxy-3',4',6'-trimethoxychalcone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6377,CAS号为 91856-16-5。 | |||
TN2866 |
3,4,5-Trimethoxycinnamyl alcohol
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Antifection | Microbiology/Virology |
3,4,5-Trimethoxycinnamyl alcohol shows significant antimicrobial and cytotoxic activities. | |||
TN6062 |
1,3,9-Trimethyluric acid
|
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1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the range of 1-3 uM. 1,3,9-Trimethyluric a | |||
TN3227 |
7-Hydroxy-2',5,8-trimethoxyflavanone
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Others | Others |
7-Hydroxy-2',5,8-trimethoxyflavanone是一种天然产物,属于唇形科黄芩属,其产品编号为 TN3227,CAS号为 100079-34-3。7-Hydroxy-2',5,8-trimethoxyflavanone可用作对照参考。 | |||
TN5420 |
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
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3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5420,CAS号为 873867-94-8。 | |||
TN2758 |
2-Ethyl-2,6,6-trimethylpiperidin-4-one
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Others | Others |
2-Ethyl-2,6,6-trimethylpiperidin-4-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2758,CAS号为 133568-79-3。 | |||
TMA0588 | 2',4',6'-Trimethoxyacetophenone | Others | Others |
2',4',6'-Trimethoxyacetophenone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TMA0588,CAS号为 832-58-6。 | |||
TN3080 | 5,6,7-Trimethoxycoumarin | P450; Antifection | Metabolism; Microbiology/Virology |
5,6,7-Trimethoxycoumarin shows moderate inhibitory activity against Micrococcus luteus, it also displays an intermediate cytotoxic effects against brine shrimp larvae. 5,6,7-Trimethoxycoumarin can improve gastroprotective effects, and it has low toxicity | |||
T79964 |
6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone
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Glucosidase | Metabolism |
6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) 是一种从决明子种子中分离得到的蒽醌类化合物,具有α-葡萄糖苷酶抑制活性(IC50: 185 μM)。 | |||
TN3095 |
5,7-Dihydroxy-3,4',8-trimethoxyflavone
|
Others | Others |
5,7-Dihydroxy-3,4',8-trimethoxyflavone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3095,CAS号为 1570-09-8。 | |||
TN6232 |
Myricetin 3,7,3'-trimethyl ether 5'-O-glucoside
|
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Myricetin 3,7,3'-trimethyl ether 5'-O-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6232,CAS号为 2170444-56-9。 | |||
TN2999 |
4-(2,6,6-Trimethyl-1-cyclohexenyl)-3-buten-2-one
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Others | Others |
4-(2,6,6-Trimethyl-1-cyclohexenyl)-3-buten-2-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2999,CAS号为 79-77-6。 | |||
T83604 |
(+)-5,7,4'-Trimethoxyafzelechin
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(+)-5,7,4'-Trimethoxyafzelechin是(+)-Afzelechin的衍生物,后者为一种α-葡萄糖苷酶活性抑制剂并可从Bergenia ligulata的根茎中分离得到。 | |||
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