|
TMPJ-01129
|
SMAD1 Protein, Human, Recombinant (GST)
hSMAD1,Transforming Growth Factor-Beta-Sig...
|
Human
|
E. coli
|
|
SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcriptional modulator SMAD 1 is activated by bone morphogenetic proteins type 1 receptor kinase. Defects in SMAD1 may cause primary pulmonary hypertension (PPH1), characterized by plexiform lesions of proliferating endothelial cells in pulmonary arterioles. The lesions lead to elevated ... |
|
TMPJ-00271
|
SMAD3 Protein, Human, Recombinant (His & Flag)
SMAD 3,Mothers against DPP homolog 3,hMAD-3,MADH3,J...
|
Human
|
E. coli
|
|
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so doing transduce the signal into the nucleus. Receptor-regulated SMAD is an intracellular signal transducer and transcriptional modulator activated by TGF-beta and activin type 1 receptor kinases. SMAD3 binds the TRE element in the promoter region of many genes that are regulated... |
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TMPH-01699
|
SMAD2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3... |
|
TMPY-03291
|
SMAD2 Protein, Mouse, Recombinant (His & GST)
mMad2,Smad-2,7120426M23Rik,Madr2,Madh2,
|
Mouse
|
Baculovirus Insect Cells
|
|
SMAD2 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD2 mediates the signal of the TGF-beta, and therefore regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. SMAD2 is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein... |
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TMPJ-01108
|
SMAD4 Protein, Human, Recombinant (His)
DPC4,SMAD 4,Deletion Target in Pancreatic Carcinoma...
|
Human
|
E. coli
|
|
SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain. It is the component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. SMAD4 promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. SMAD4 may act as a tumo... |
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TMPY-04203
|
RAB1B Protein, Human, Recombinant (hFc)
RAB1B, member RAS oncogene family
|
Human
|
HEK293 Cells
|
|
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC cells in vitro and in vivo. Mechanistically, loss of RAB1B resulted in elevated expression of TGF-beta receptor 1 (TbetaR1) through decreased degradation of ubiquitin, increased levels of phosphorylated SMAD3 and TGF-beta-induced epithelial-mesenchymal transition (EMT). Furthermo... |
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TMPJ-00966
|
GDF-5 Protein, Human, Recombinant
Lipopolysaccharide-associated protein 4,Cartilage-derived mo...
|
Human
|
E. coli
|
|
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor protein consisting of a 354 amino acid (aa) Nterminal proregion and a 120 aa C-terminal mature peptide. Mature human GDF-5 shares 99% aa sequence identity with both mature mouse and rat GDF-5. GDF-5 signaling is mediated by formation of a heterodimeric complex consisting of a ty... |
|
TMPY-01654
|
ITCH Protein, Human, Recombinant (aa 526-903)
itchy E3 ubiquitin protein ligase,NAPP1,dJ468O1...
|
Human
|
E. coli
|
|
E3 ubiquitin-protein ligase Itchy homolog, also known as Atrophin-1-interacting protein 4, NFE2-associated polypeptide 1, NAPP1, and ITCH, is a cell membrane protein that contains one C2 domain, one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and contains four WW domains. ITCH acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-... |
|
TMPY-04468
|
STK16 Protein, Human, Recombinant (His & NusA)
MPSK,serine/threonine kinase 16,TSF1,KRCT,...
|
Human
|
E. coli
|
|
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is ubiquitously expressed at very low levels. STK16 / MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or c... |
|
TMPY-00681
|
BMP-5 Protein, Human, Recombinant (hFc)
bone morphogenetic protein 5
|
Human
|
HEK293 Cells
|
|
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way sugges... |
|
TMPY-04451
|
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β1, γ1)
|
Human
|
Baculovirus Insect Cells
|
|
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1. |
|
TMPY-03878
|
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...
|
Human
|
HEK293 Cells
|
|
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. |
|
TMPY-02501
|
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...
|
Human
|
HEK293 Cells
|
|
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. |
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TMPY-03745
|
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...
|
Human
|
HEK293 Cells
|
|
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. |
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TMPY-02245
|
SNAP-25 Protein, Human, Recombinant (His)
synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ
|
Human
|
E. coli
|
|
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp... |
|
TMPK-00383
|
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
ACE2,ACE-2,ACEH
|
Human
|
HEK293 Cells
|
|
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A... |
|
TMPY-01147
|
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
RSPO,CRISTIN3,R-spondin 1
|
Human
|
HEK293 Cells
|
|
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1. |
|
TMPY-01850
|
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC11987...
|
Human
|
HEK293 Cells
|
|
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... |
|
TMPY-01938
|
CD98 Protein, Human, Recombinant (His)
4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...
|
Human
|
HEK293 Cells
|
|
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1. |
|
TMPY-01894
|
SIGIRR Protein, Human, Recombinant (His)
TIR8,single immunoglobulin and toll-interleukin 1 r...
|
Human
|
HEK293 Cells
|
|
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1. |
|
TMPY-01281
|
ACVR2B Protein, Mouse, Recombinant (His)
ActRIIB,activin A receptor, type IIB,4930516B21...
|
Mouse
|
HEK293 Cells
|
|
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1. |
|
TMPY-01258
|
IL-13RA1 Protein, Human, Recombinant (His)
NR4,interleukin 13 receptor, alpha 1,CD2
|
Human
|
HEK293 Cells
|
|
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1. |
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TMPY-01827
|
CD30/TNFRSF8 Protein, Human, Recombinant (His)
D1S166E,tumor necrosis factor receptor sup...
|
Human
|
HEK293 Cells
|
|
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1. |
|
TMPY-04346
|
PD-L2 Protein, Human, Recombinant (His)
PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...
|
Human
|
HEK293 Cells
|
|
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. |
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TMPY-02525
|
RGMA Protein, Human, Recombinant (His)
repulsive guidance molecule family member a,RGM
|
Human
|
HEK293 Cells
|
|
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form... |
|
TMPY-00861
|
IL-33 Protein, Human, Recombinant
IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...
|
Human
|
E. coli
|
|
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1. |
|
TMPY-01247
|
FLT3 Protein, Human, Recombinant (T227M, His)
FLK2,FLK-2,CD135,STK1,fms-related tyrosine...
|
Human
|
HEK293 Cells
|
|
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1. |
|
TMPY-01185
|
DR5/TRAIL R2 Protein, Human, Recombinant (His)
KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...
|
Human
|
HEK293 Cells
|
|
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1. |
|
TMPY-05220
|
TSLP Protein, Human, Recombinant (R127A & R130S, His)
thymic stromal lymphopoietin
|
Human
|
HEK293 Cells
|
|
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1. |
|
TMPY-06418
|
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
R-spondin 2,CRISTIN2
|
Human
|
HEK293 Cells
|
|
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1. |
|
TMPY-02813
|
ErbB4 Protein, Human, Rhesus, Recombinant (His)
erb-b2 receptor tyrosine kinase 4
|
Human,Rhesus
|
HEK293 Cells
|
|
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1. |
|
TMPY-06873
|
FLT3 Ligand Protein, Human, Recombinant
FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL
|
Human
|
E. coli
|
|
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1. |
|
TMPY-01883
|
EPOR Protein, Human, Recombinant (His)
erythropoietin receptor,EPO-R
|
Human
|
HEK293 Cells
|
|
EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1. |
|
TMPY-04970
|
TIGIT Protein, Human, Recombinant (hFc)
WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...
|
Human
|
HEK293 Cells
|
|
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1. |
|
TMPY-04939
|
LAG-3 Protein, Human, Recombinant
LAG-3,lymphocyte-activation gene 3,CD223
|
Human
|
HEK293 Cells
|
|
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1. |
|
TMPY-04348
|
CTLA-4 Protein, Human, Recombinant (His)
ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...
|
Human
|
HEK293 Cells
|
|
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1. |
|
TMPY-00947
|
VCAM-1 Protein, Human, Recombinant (hFc)
INCAM-100,CD106,VCAM-1,vascular c...
|
Human
|
HEK293 Cells
|
|
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1. |
|
TMPY-04165
|
FGFR3 Protein, Human, Recombinant (His)
JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...
|
Human
|
HEK293 Cells
|
|
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1. |
|
TMPY-01137
|
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE...
|
Human
|
HEK293 Cells
|
|
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1. |
|
TMPY-01146
|
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
HHF5,CD220,insulin receptor
|
Human
|
HEK293 Cells
|
|
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1. |
|
TMPY-02033
|
CD44 Protein, Human, Recombinant (His)
CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...
|
Human
|
HEK293 Cells
|
|
CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1. |
|
TMPY-01744
|
ACVR2A Protein, Human, Recombinant (His)
activin A receptor, type IIA,ACVR2,ACTRII
|
Human
|
HEK293 Cells
|
|
ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1. |
|
TMPY-03967
|
BTN3A3 Protein, Human, Recombinant (His)
BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3
|
Human
|
HEK293 Cells
|
|
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1. |
|
TMPY-01851
|
CD73 Protein, Human, Recombinant (His)
eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...
|
Human
|
HEK293 Cells
|
|
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1. |
|
TMPY-01949
|
CD19 Protein, Human, Recombinant (His)
CD19 molecule,B4,CVID3
|
Human
|
HEK293 Cells
|
|
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1. |
|
TMPY-00978
|
Progranulin Protein, Human, Recombinant (His)
PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...
|
Human
|
HEK293 Cells
|
|
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1. |
|
TMPY-05208
|
PD-L1 Protein, Human, Recombinant
CD274 molecule,PDCD1L1,PD-L1,PDL<...
|
Human
|
HEK293 Cells
|
|
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1. |
|
TMPY-02779
|
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
thyroid peroxidase,MSA,TPX,TDH2A
|
Human
|
Baculovirus Insect Cells
|
|
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i... |
|
TMPY-03407
|
NQO1 Protein, Human, Recombinant (His)
NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...
|
Human
|
E. coli
|
|
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex... |
|
TMPY-00853
|
IL-1RA Protein, Human, Recombinant
DIRA,IL1RA,interleukin 1 receptor antagoni...
|
Human
|
E. coli
|
|
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1. |
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