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98

抑制剂 & 化合物

28

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T18514	PAC	Others	Others
	PAC is a chemical conjugate consisting of an ADCs linker and PROTACs linked to an antibody. When PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) in comparison to PROTAC alone.
T2503	PAC-1 Procaspase activating compound 1	Apoptosis; Caspase; Autophagy	Apoptosis; Autophagy; Proteases/Proteasome
	PAC-1 (Procaspase activating compound 1) 是一种 procaspase-3激活剂，诱导癌细胞凋亡，EC50为 2.08 μM，可用于研究淋巴瘤、黑色素瘤、实体瘤、乳腺癌和胸癌等治疗的试验。
T37139	5'-O-DMT-PAC-dA
	5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1]. [1]. Schulhof JC, et, al. The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups. Nucleic Acids Res. 1987 Jan 26;15(2):397-416.
T16426	Asivatrep PAC-14028	Others	Others
	Asivatrep is an effective and selective transient receptor potential vanilloid type I antagonist.
T18603	PROTAC BRD4 degrader for PAC-1	Others	Others
	PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective proteolysis of PAC-1.
T74121	DMT-dA(PAc) Phosphoramidite
	DMT-dA(PAc) Phosphoramidite 是一种亚磷酰胺单体，可用于 DNA 或 RNA 的合成。
T78105	PAC1R antagonist 1	PACAP	GPCR/G Protein
	PAC1R antagonist 1为一种具有口服活性的 PAC1 受体拮抗剂，可抑制由垂体腺苷酸环化酶激活多肽（PACAP）及神经损伤所诱导的异常性疼痛，可用于研究肿瘤和与免疫相关的疾病。
TNU1202	3’,5’-TIPS-N-PAc-Guanosine
	Nucleoside Derivatives - Protected nucleosides with NH2/OH open
TP1618L	PACAP-38 (31-38), human, mouse, rat acetate PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)	PACAP	GPCR/G Protein
	PACAP-38 (31-38), human, mouse, rat acetate 是 PAC1 受体的激活剂。PACAP-38 (31-38), human, mouse, rat acetate 对交感神经元 NPY 和儿茶酚胺的产生具有强效、有效和持续的刺激作用，可用于神经营养和神经保护研究。
T41277	PACMA 31	Others	Others
	PACMA 31 是一种不可逆的共价蛋白二硫键异构酶 (PDI) 抑制剂，IC50 为 10 μM。 PACMA 31 显着抑制卵巢肿瘤生长并表现出肿瘤靶向能力。
TQ0245	Sapacitabine CS682,CYC682	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Sapacitabine is a nucleoside analog prodrug with antitumor activity.
T3548	Epacadostat INCB 024360,艾卡哚司他,IDO Inhibitor 1	IDO; Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	Epacadostat (INCB 024360) 是选择性的IDO1抑制剂，IC50=71.8 nM。
TP1878L	PACAP 1-38 acetate	PACAP	GPCR/G Protein
	PACAP 1-38 acetate 是一种垂体腺苷酸环化酶激活多肽 (PACAP) 类似物。它与 PACAP I 型受体 (IC50 = 4 nM) 和 PACAP II 型 VIP2 受体 (IC50 = 1 nM) 结合，但不与 PACAP II 型 VIP1 受体结合。
T24449	Mepacrine Haffkinine,Erion	Others	Others
	Mepacrine (Erion) 是一种吖啶衍生物，以前广泛用作抗疟药。它在细胞生物学实验中用作磷脂酶A2的抑制剂。
T6020	Pacritinib SB1518	FLT; Tyrosine Kinases; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Pacritinib (SB1518) 是一种野生型 JAK2和 JAK2V617F 突变型抑制剂，IC50分别为 23 和 19 nM。它也抑制 FLT3及其突变型 FLT3D835Y，IC50分别为 22 和 6 nM。
T27635	Isoxepac 伊索克酸,Olopatadine USP Related Compound C	Others	Others
	Isoxepac (Olopatadine USP Related Compound C) 是非甾体抗炎剂，显示出抗炎、镇痛和解热活性，已在多种动物模型中进行了相关研究。
TP1722L	PACAP (6-38), human, ovine, rat acetate	PACAP	GPCR/G Protein
	PACAP (6-38), human, ovine, rat acetate 是一种有效的 PACAP 受体拮抗剂。PACAP (6-38) 作用于 PACAP I 型受体，PACAP II 型受体 VIP1 和 PACAP II 型受体 VIP2，IC50 分别为 30 nM，600 nM 和 40 nM。
T11212	EPAC 5376753 5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione	cAMP	GPCR/G Protein
	EPAC 5376753 是 EPAC1 的变构抑制剂，在瑞士 3T3 细胞中的 IC50 为 4 µM。
T38273	Paclobutrazol (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol	Antifungal	Microbiology/Virology
	Paclobutrazol ((R,R)-paclobutrazol) 是一种含有三唑的植物生长延缓剂，能抑制赤霉素的生物合成。Paclobutrazol 还具有抗真菌 (antifungal) 活性。Paclobutrazol 能抑制脱落酸的合成，诱导植物的耐冷性植物。Paclobutrazol 通常用于赤霉素在植物生物学中作用的研究。
T29067L	Upacicalcet HCl Upacicalcet HCl(1333218-50-0 Free base)	CaSR	GPCR/G Protein
	Upacicalcet HCl 是一种静脉内拟钙剂，通过直接作用于甲状旁腺细胞膜钙敏感受体来抑制过量的甲状旁腺激素 (PTH) 分泌，从而降低血液中的 PTH 水平。Upacicalcet HCl 可用于治疗血液是一种新型继发性甲状旁腺功能亢进化合物，靶向钙敏感受体的氨基酸结合位点。
T4545	Propacetamol Hydrochloride 盐酸丙帕他莫,Propacetamol HCL	Others	Others
	Propacetamol Hydrochloride (Propacetamol HCL) 是 paracetamol(acetaminophen) 的前药，具有改善的水溶性。当口服非甾体抗炎药不合适或矛盾时，丙帕西莫是一种静脉给药的镇痛药。
TP1070L	PACAP (1-27), human, ovine, rat acetate PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base)	PACAP	GPCR/G Protein
	PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate)(127317-03-7 free base) 是一种新的神经肽，最初从牛下丘脑中分离出来，也存在于人和大鼠中。
T29067	Upacicalcet PLS-240,SK-1403,AJT-240	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Upacicalcet (AJT-240) 是一种静脉内拟钙剂，是一种可用于人血液透析的 SHPT，通过直接作用于甲状旁腺细胞膜钙敏感受体来抑制过量的甲状旁腺激素 (PTH) 分泌，从而降低血液中的 PTH 水平。 3 Upacicalcet 是钙敏感受体的正变构调节剂，可预防大鼠腺嘌呤诱导的继发性甲状旁腺功能亢进模型中的血管钙化和骨骼疾病。
T21907	PACOCF3 1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone	Phospholipase	Metabolism
	PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromethylketone) 是一种钙非依赖性的磷脂酶 A2 (phospholipase A2) 抑制剂，IC50为 3.8 μM。PACOCF3 改变肾小管细胞中的 Ca2+信号传导。
T20864	7-Troc-paclitaxel	Others	Others
	7-Troc-paclitaxel 是紫杉醇的前体，紫杉醇具有抗肿瘤活性。
T37435	PACAP-related Peptide (rat) (trifluoroacetate salt)	PACAP	GPCR/G Protein
	PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in rat hypothalamus as well as within the nerves of the median eminence, the anterior pituitary, bed nucleus of the stria terminalis, cerebellum, cerebral cortex, and amygdala. PRP is also expressed in vaginal, uterine cervica...
T124630	Carpachromene
	Carpachromene 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124630。
T33861	Paclitaxel-MVCP
	Paclitaxel-MVCP ( MC-val-cit-pab-paclitaxel )is a paclitaxel derivative with an MC-Val-Cit-PAB linker, which can be used for the preparation of Paclitaxel conjugates for drug delivery and nanomedicine research.
T77128	Pacmilimab
	Pacmilimab (CX-072) 是一种有效的PD-L1抑制剂。 Pacmilimab 显示出抗肿瘤活性。
T126370	Dopacetamide
	Dopacetamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126370，CAS号为 1129-53-9。
T73863	PPACK II
	PPACK II 是一种不可逆的特异性腺体和血浆激肽释放酶 (kallikreins) 抑制剂。
T77127	Pacanalotamab
	Pacanalotamab (AMG 420；BI-836909) 是一种双特异性 T 细胞接合剂 (BiTE)，靶向 BCMA 和 CD3ɛ。BCMA 是指 B 细胞成熟抗原，而 Pacanalotamab 会将 T 细胞重定向到细胞表面的 BCMA 表达细胞。Pacanalotamab 可对人多发性骨髓瘤 (MM) 细胞系进行 T 细胞重定向裂解。
T75594	Harpactira Baviana Venom
	Harpactira Baviana Venom (Baboon Tarantula Venom) 是一种蜘蛛毒液，能够从皇帝巴布蜘蛛蜘蛛中获得。Harpactira Baviana Venom 可以调节 NaV1.8和诱导痛觉过敏。
TP1414	PACAP-38 (31-38), human, mouse, rat TFA
	PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.
T83510	[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2 BM-PACAP
	[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) 为合成PACAP 1-27 类似物，展现出明显的松弛效应。
T81571	PACAP (1-38) free acid TFA
	PACAP (1-38) free acid TFA，一种内源性神经肽，能有效促进胃窦运动，增强体液蛋白分泌，同时抑制胃泌素释放。此外，它刺激血管活性肠肽、胃泌素释放肽和P物质的释放，并通过RACK1增强N-甲基-D-天门冬氨酸受体功能及脑源性神经营养因子表达。
T81572	PACAP (1-38) free acid
	PACAP (1-38) free acid 是一种具有多重生物功能的内源性神经肽，主要作用包括刺激胃窦运动、增进体液蛋白分泌、抑制胃泌素分泌，以及促进血管活性肠肽、胃泌素释放肽和P 物质的释放。此外，PACAP (1-38) free acid 通过与RACK1互作，可以增强N-甲基-D-天门冬氨酸受体的功能并促进脑源性神经营养因子的表达。
T70114	Paclitaxel Ceribate
	Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.
T70006	DHA-paclitaxel
	DHA-paclitaxel, also know as Taxoprexin, is prodrug comprised of the naturally occurring omega-3 fatty acid docosahexaenoic acid (DHA) covalently conjugated to the anti-microtubule agent paclitaxel. Because tumor cells take up DHA, DHA-paclitaxel is delivered directly to tumor tissue, where the paclitaxel moiety binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. Paclitaxel also induces apoptosis by binding to and blocking the func...
T25977	Ppack trifluoroacetate Ppack trifluoroacetate salt
	Ppack trifluoroacetate is a peptide derivative that irreversibly and specifically suppresses thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki: 0.24 nM). It has been utilized as an anticoagulant (100 μM
T69421	Hydrolapachol
	Hydrolapachol is a novel potent and selective inhibitor of schistosoma mansoni dihydroorotate dehydrogenase (smdhodh)
T66146	(SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-Palladium
	(SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-Palladium 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66146，CAS号为 1028206-56-5。
T36896	6α-hydroxy Paclitaxel 6alpha-hydroxypaclitaxel	Drug Metabolite	Metabolism
	6α-hydroxy Paclitaxel (6α-OH-PTX) 是抗癌化合物紫杉醇的主要代谢产物，具有部分细胞毒性。
T33860	Pacifenol
	Pacifenol is a sesquiterpene isolated from sea weeds and marine alga Laurencia claviformis.
T28289	Paclitaxel-SMCC SMCC taxol, Taxol-SMCC, Taxol SMCC,Paclitaxel with SMCC linker,SMCC-Taxol,Paclitaxel ADC conjugate.
	Paclitaxel-SMCC is a paclitaxel derivative with a SMCC linker. (Succinimidyl-4-( N -maleimidomethyl)cyclohexane-1-carboxylate). Paclitaxel-SMCC can be used to synthesize Paclitaxel bioconjugates with enzymes, antobodies, antigens and other biopolymers. Pa
T28290	Pactimibe CS 505,CS-505,CS505,Pactimibe free base,帕替麦布
	Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity.
TP1069	PACAP (1-27), human, ovine, rat TFA PACAP 1-27 TFA
	PACAP (1-27), human, ovine, rat TFA (PACAP 1-27 TFA) is an N-terminal fragment of pacap-38 and an effective PACAP receptor antagonist. The IC50s for rat PAC1, rat VPAC1 and human VPAC2 are 3nm, 2nm and 5nm respectively.
T80069	PACAP (6-27) (human, ovine, rat) Pituitary adenylate cyclase-activating peptide (6-27)
	PACAP (6-27) (human, ovine, rat) 是一种对PACAP受体具有拮抗作用的化合物，可以抑制犬肾上腺对外源性VIP的反应。此化合物在心血管疾病和神经系统疾病研究中展现出应用潜力。
T20505	PPACK D-Phe-pro-arg CH2Cl
	PPACK is a synthetic peptide derivative. It also irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM).
T36427	PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)	PACAP	GPCR/G Protein
	Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, ...

化合物

Cat.No: T18514

Target: Others

Cat.No: T2503

Synonym: Procaspase activating compound 1

Target: Apoptosis, Caspase, Autophagy

5'-O-DMT-PAC-dA

Cat.No: T37139

Cat.No: T16426

Synonym: PAC-14028

Target: Others

PROTAC BRD4 degrader for PAC-1

Cat.No: T18603

Target: Others

DMT-dA(PAc) Phosphoramidite

Cat.No: T74121

PAC1R antagonist 1

Cat.No: T78105

Target: PACAP

3’,5’-TIPS-N-PAc-Guanosine

Cat.No: TNU1202

PACAP-38 (31-38), human, mouse, rat acetate

Cat.No: TP1618L

Synonym: PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)

Target: PACAP

Cat.No: T41277

Target: Others

Cat.No: TQ0245

Synonym: CS682,CYC682

Target: Nucleoside Antimetabolite/Analog

Cat.No: T3548

Synonym: INCB 024360,艾卡哚司他,IDO Inhibitor 1

Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)

PACAP 1-38 acetate

Cat.No: TP1878L

Target: PACAP

Cat.No: T24449

Synonym: Haffkinine,Erion

Target: Others

Cat.No: T6020

Synonym: SB1518

Target: FLT, Tyrosine Kinases, JAK

Cat.No: T27635

Synonym: 伊索克酸,Olopatadine USP Related Compound C

Target: Others

PACAP (6-38), human, ovine, rat acetate

Cat.No: TP1722L

Target: PACAP

Cat.No: T11212

Synonym: 5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Target: cAMP

Paclobutrazol

Cat.No: T38273

Synonym: (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol

Target: Antifungal

Upacicalcet HCl

Cat.No: T29067L

Synonym: Upacicalcet HCl(1333218-50-0 Free base)

Target: CaSR

Propacetamol Hydrochloride

Cat.No: T4545

Synonym: 盐酸丙帕他莫,Propacetamol HCL

Target: Others

PACAP (1-27), human, ovine, rat acetate

Cat.No: TP1070L

Synonym: PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base)

Target: PACAP

Cat.No: T29067

Synonym: PLS-240,SK-1403,AJT-240

Target: Calcium Channel

Cat.No: T21907

Synonym: 1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone

Target: Phospholipase

7-Troc-paclitaxel

Cat.No: T20864

Target: Others

PACAP-related Peptide (rat) (trifluoroacetate salt)

Cat.No: T37435

Target: PACAP

Cat.No: T124630

Paclitaxel-MVCP

Cat.No: T33861

Cat.No: T77128

Cat.No: T126370

Cat.No: T73863

Pacanalotamab

Cat.No: T77127

Harpactira Baviana Venom

Cat.No: T75594

PACAP-38 (31-38), human, mouse, rat TFA

Cat.No: TP1414

[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2

Cat.No: T83510

Synonym: BM-PACAP

PACAP (1-38) free acid TFA

Cat.No: T81571

PACAP (1-38) free acid

Cat.No: T81572

Paclitaxel Ceribate

Cat.No: T70114

DHA-paclitaxel

Cat.No: T70006

Ppack trifluoroacetate

Cat.No: T25977

Synonym: Ppack trifluoroacetate salt

Cat.No: T69421

(SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-Palladium

Cat.No: T66146

6α-hydroxy Paclitaxel

Cat.No: T36896

Synonym: 6alpha-hydroxypaclitaxel

Target: Drug Metabolite

Cat.No: T33860

Paclitaxel-SMCC

Cat.No: T28289

Synonym: SMCC taxol, Taxol-SMCC, Taxol SMCC,Paclitaxel with SMCC linker,SMCC-Taxol,Paclitaxel ADC conjugate.

Cat.No: T28290

Synonym: CS 505,CS-505,CS505,Pactimibe free base,帕替麦布

PACAP (1-27), human, ovine, rat TFA

Cat.No: TP1069

Synonym: PACAP 1-27 TFA

PACAP (6-27) (human, ovine, rat)

Cat.No: T80069

Synonym: Pituitary adenylate cyclase-activating peptide (6-27)

Cat.No: T20505

Synonym: D-Phe-pro-arg CH2Cl

PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

Cat.No: T36427

Target: PACAP

Cat. No.	Product Name	Target	Signaling Pathways
T6S1884	Benzoylhypaconine 苯甲酰次乌头碱,Benzoylhypacoitine,苯甲酰次乌头原碱	Others	Others
	Benzoylhypaconine (Benzoylhypacoitine) 是来自 Aconitum 中的一种单酯生物碱，也是Aconitum 的主要药理和毒性成分。
T6S0619	Pachymic acid 3-O-Acetyltumulosic acid,茯苓酸	ERK; Akt	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Pachymic acid (3-O-Acetyltumulosic acid) 是来自茯苓的一种三萜，可抑制Akt 和ERK 信号传导途径。
TN1563	Dehydropachymic acid	Autophagy; Immunology/Inflammation related	Autophagy; Immunology/Inflammation
	Dehydropachymic acid 是从茯苓中分离出的一种三萜类天然产物，有抗炎活性。
T5749	10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetylpaclitaxel 7-Xyloside	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) 是一种紫杉醇衍生物，具有改进的药理特性和更高的水溶性，用于治疗癌症。
T32570	Lappaconine 20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine	Others	Others
	Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) 衍生自去甲二萜生物碱。
T4136	Lapachol Bethabarra wood,CI75490,黄钟花醌,Greenhartin,Tecomin	Others; Influenza Virus; Antibacterial; Parasite; Antifungal	Microbiology/Virology; Others
	Lapachol (CI75490) 是从Tabebuia avellanedae 中分离得到的一种萘醌。它具有具有抗菌、抗炎、镇痛、抗肿瘤和抗生素特性。
TN7058	Dihydrolapachenole 6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene	Others	Others
	Dihydrolapachenole (6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene) 可分离自T. chrysantha。
T6560	Lappaconitine hydrobromide 氢溴酸高乌甲素,Lappaconite HBr,Allapinine	Others	Others
	Lappaconitine hydrobromide (Allapinine) 是天然生物碱类化合物，具有抗心律失常作用。
T5738	7-Epi 10-desacetyl paclitaxel 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol,7-表-10-去乙酰基云南紫杉宁A	Others	Others
	7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) 是紫杉醇衍生物，对 HeLa 细胞具有细胞毒性(IC50:85 μM)。
T37267	Pachybasin	Antibacterial	Microbiology/Virology
	Pachybasin 是一种蒽醌真菌代谢物。 Pachybasin 对大肠杆菌、枯草芽孢杆菌、M. luteus、S. cerevisiae、C. albicans、A. niger 和 A. flavus 具有抗菌活性，MIC 值为 64.0 μg/mL，对金黄色葡萄球菌具有抗菌活性和尖孢镰刀菌，MIC 值分别为 32.0 和 16.0 μg/mL。
TN1375	α-Lapachone ALPHA-拉杷醌,alpha-Lapachone	Topoisomerase; Antifection	DNA Damage/DNA Repair; Microbiology/Virology
	α-Lapachone 具有杀锥虫作用。
T6S0630	Hypaconitine	P450; TNF	Apoptosis; Metabolism
	Hypaconitine 是从乌头属种分离的一种高毒性成分，可研究风湿病。
T6407	β-Lapachone 3,4-二氢-2,2-二甲基-2H-萘并[1,2-B]吡喃-5,6-二酮,Beta-Lapachone,NSC-26326,SL-11001,ARQ-501	IDO; Apoptosis; Topoisomerase; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism
	β-Lapachone (ARQ-501) 是一种萘醌类天然产物，是拓扑异构酶 I 抑制剂，通过抑制细胞周期进程来诱导细胞凋亡。
T2806	Lappaconitine 高乌甲素,(+)-Lappaconitine	P2X Receptor; Sodium Channel	Membrane transporter/Ion channel; Neuroscience
	Lappaconitine ((+)-Lappaconitine) 是从高乌头中分离得到的一种天然产物，可用于缓解疼痛的研究。
TN1754	Hypaconine	Others	Others
	Hypaconine 是一种 C19-二萜生物碱，从乌头和飞燕草属中分离出来得到。它表现出强烈的心脏活性。
T38815	Millepachine	Apoptosis	Apoptosis
	Millepachine 是分离自中草药Millettia pachycarpaBenth 的查尔酮，在体内外对多种人类癌细胞均显示出强大的抗增殖作用。
T0968	Paclitaxel Taxol,紫杉醇,NSC 125973	Apoptosis; Microtubule Associated; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling
	Paclitaxel (Taxol) 属于天然产物，是一种微管聚合物稳定剂。Paclitaxel 具有抗肿瘤活性；通过诱导有丝分裂停滞、细胞凋亡、细胞自噬等，导致细胞死亡。
TN1569	Deoxylapachol	Antifection; Antifungal	Microbiology/Virology
	Deoxylapachol 是新西兰褐藻Landsburgia quercifolia 的主要细胞毒性成分，有抗真菌和抗癌活性。
TN4731	Pachyaximine A	Antifection	Microbiology/Virology
	Pachyaximine A possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. (-)-Pachyaximine A demonstrates significant activity as antiestrogen binding site (AEBS
TN3318	9-Hydroxy-alpha-lapachone	Antifection	Microbiology/Virology
	9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. It may have anti-inflammatory activity, it exhibits potent inhi
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1 1.Balan, J., Ebringer, L., Nemec, P., et al.Ant...
TN4732	Pachysamine M	Others	Others
	Pachysamine M shows inhibitory activities against multiple types of cancer cells.
TN3321	9-Methoxy-alpha-lapachone	Others	Others
	9-Methoxy-alpha-lapachone has antitumor-promoting effect, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein- Barr virus early antigen (EBV-EA) activation in Raji cells.
TN3899	Drupacine	Others	Others
	Drupacine and a crude alkaloid extract suppress nematode hatch, activity of mixed life stages, and population numbers on plant roots.
TN2032	Pachypodol 霍香黃酮醇	Antifection	Microbiology/Virology
	Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida galabrata.
TN3019	4,9-Dihydroxy-alpha-lapachone	Others	Others
	4,9-Dihydroxy-alpha-lapachone has antitumor-promoting effects, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation in Raji cells. 4,9-Dihydroxy-alpha-l
TN1247	3-Epidehydropachymic acid	Others	Others
	3-Epidehydropachymic acid is a natural product
TN6657	4-(Dimethylamino)cinnamaldehyde
	4-Dimethylaminocinnamaldehyde is a photometric reagent for primary aromatic amines. The 4-(dimethylamino)cinnamaldehyde assay is currently used to quantify proanthocyanidin (PAC) content in cranberry products.

天然产物

Benzoylhypaconine

Cat.No: T6S1884

Synonym: 苯甲酰次乌头碱,Benzoylhypacoitine,苯甲酰次乌头原碱

Target: Others

Pachymic acid

Cat.No: T6S0619

Synonym: 3-O-Acetyltumulosic acid,茯苓酸

Target: ERK, Akt

Dehydropachymic acid

Cat.No: TN1563

Target: Autophagy, Immunology/Inflammation related

10-Deacetyl-7-xylosyl paclitaxel

Cat.No: T5749

Synonym: 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetylpaclitaxel 7-Xyloside

Target: Others, Microtubule Associated

Cat.No: T32570

Synonym: 20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine

Target: Others

Cat.No: T4136

Synonym: Bethabarra wood,CI75490,黄钟花醌,Greenhartin,Tecomin

Target: Others, Influenza Virus, Antibacterial, Parasite, Antifungal

Dihydrolapachenole

Cat.No: TN7058

Synonym: 6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene

Target: Others

Lappaconitine hydrobromide

Cat.No: T6560

Synonym: 氢溴酸高乌甲素,Lappaconite HBr,Allapinine

Target: Others

7-Epi 10-desacetyl paclitaxel

Cat.No: T5738

Synonym: 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol,7-表-10-去乙酰基云南紫杉宁A

Target: Others

Cat.No: T37267

Target: Antibacterial

Cat.No: TN1375

Synonym: ALPHA-拉杷醌,alpha-Lapachone

Target: Topoisomerase, Antifection

Cat.No: T6S0630

Target: P450, TNF

Cat.No: T6407

Synonym: 3,4-二氢-2,2-二甲基-2H-萘并[1,2-B]吡喃-5,6-二酮,Beta-Lapachone,NSC-26326,SL-11001,ARQ-501

Target: IDO, Apoptosis, Topoisomerase, Autophagy

Cat.No: T2806

Synonym: 高乌甲素,(+)-Lappaconitine

Target: P2X Receptor, Sodium Channel

Cat.No: TN1754

Target: Others

Cat.No: T38815

Target: Apoptosis

Cat.No: T0968

Synonym: Taxol,紫杉醇,NSC 125973

Target: Apoptosis, Microtubule Associated, Autophagy

Cat.No: TN1569

Target: Antifection, Antifungal

Pachyaximine A

Cat.No: TN4731

Target: Antifection

9-Hydroxy-alpha-lapachone

Cat.No: TN3318

Target: Antifection

Cat.No: T35750

Pachysamine M

Cat.No: TN4732

Target: Others

9-Methoxy-alpha-lapachone

Cat.No: TN3321

Target: Others

Cat.No: TN3899

Target: Others

Cat.No: TN2032

Synonym: 霍香黃酮醇

Target: Antifection

4,9-Dihydroxy-alpha-lapachone

Cat.No: TN3019

Target: Others

3-Epidehydropachymic acid

Cat.No: TN1247

Target: Others

4-(Dimethylamino)cinnamaldehyde

Cat.No: TN6657

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