102
45
32
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T83900 |
12β-Hydroxyisocholic Acid
LCA,Lagocholic Acid |
||
12β-Hydroxyisocholic acid是一种胆酸,同时也是胆酸的异构体。在酒精性肝损伤的小鼠模型中,12β-Hydroxyisocholic acid的肝脏水平会升高。 | |||
T21841 |
(±)-Hexanoylcarnitine chloride
DL-Hexanoylcarnitine chloride |
Others | Others |
(±)-Hexanoylcarnitine chloride 是一种脂肪酸代谢产物,能将脂肪酸分解成能够被身体利用的小分子化合物。(±)-Hexanoylcarnitine chloride 可通过大鼠骨骼肌毒性特异性从而作为一种生物标志物。 | |||
T9522 |
Rimtuzalcap
CAD-1883 |
Potassium Channel | Membrane transporter/Ion channel |
Rimtuzalcap (CAD-1883) 是首创的,选择性的小电导钙激活钾通道 (SK 通道) 正变构调节剂。Rimtuzalcap 可用于运动障碍的研究,包括脊髓小脑性共济失调 (SCA)和特发性震颤 (ET)。 | |||
T9065 |
4-Isopropylcatechol
|
Others | Others |
4-Isopropylcatechol 是一种有效的脱色剂,可用于特定黑色素沉着症患者的局部治疗。 | |||
T22484 |
(±)-Propionylcarnitine chloride
Propionyl-DL-carnitine chloride |
Endogenous Metabolite | Metabolism |
(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) 是一种短链酰基肉碱的混合物,可用作膳食补充剂,可用于研究慢性糖尿病。 | |||
T7340 |
5'-N-Ethylcarboxamidoadenosine
NECA,5'-N-乙基酰胺基腺苷 |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
5'-N-Ethylcarboxamidoadenosine (NECA) 是腺苷受体的激动剂,可增加荧光素和低分子量葡聚糖的脑外渗,与血脑屏障调节无关。 | |||
TPL0366 |
4-Biphenylcarboxylic acid
|
||
4-Biphenylcarboxylic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 TPL0366,CAS号为 92-92-2。 | |||
TP1236 |
Etelcalcetide hydrochloride
AMG 416 hydrochloride,维考西肽盐酸盐,KAI-4169 hydrochloride |
CaSR | GPCR/G Protein |
Etelcalcetide hydrochloride (AMG 416 hydrochloride) 是具有有钙敏感受体 (CaSR) 活化剂作用的合成肽,能够减少接受血液透析的继发性甲状旁腺功能亢进患者的甲状旁腺激素 (PTH) 浓度。 | |||
T76682 |
Galcanezumab
LY 2951742 |
CGRP Receptor | GPCR/G Protein; Neuroscience |
Galcanezumab 是一种靶向 CGRP 配体的人源化 IgG4 单克隆抗体,是一种与配体降钙素基因相关肽结合的抗体。Galcanezumab 可用于预防和治疗偏头痛或丛集性头痛。 | |||
T18968 |
Dansylcadaverine
Monodansyl cadaverine,丹酰尸胺 |
Others; Autophagy | Autophagy; Others |
Dansylcadaverine (Monodansyl cadaverine) 是谷氨酰胺转胺酶的高亲和力底物,能阻断受体介导的多种配体的内吞作用。它是一种用于标记自噬空泡的荧光探针。 | |||
T2533 |
Alcaftadine
R89674,Lastacaft,阿卡他定 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Alcaftadine (Lastacaft) 是一种 H1 组胺受体拮抗剂,用于预防与过敏性结膜炎相关的瘙痒。它是一种广谱抗组胺剂,对组胺H1和H2受体具有高亲和力,对H4受体的亲和力较低,还具有调节免疫细胞募集和肥大细胞稳定的作用。 | |||
T20388 |
9-Ethylcarbazole
N-乙基咔唑,NSC60585,N-Ethylcarbazole,NSC-60585,NSC 60585 |
Others | Others |
9-Ethylcarbazole (NSC-60585) 是一种生化剂。 | |||
TP1088 |
N-Acetylcarnosine
N-Acetyl-L-carnosine,N-乙酰肌肽 |
Others | Others |
N-Acetylcarnosine (N-Acetyl-L-carnosine) 是一种含有组氨酸的天然二肽,是药理学上主要的 L-carnosine 的来源。它是一种眼科药物,对人类白内障具有潜在的应用价值。 | |||
T1420 |
Diethylcarbamazine citrate
Caritrol,枸橼酸乙胺嗪,Loxuran,Dicarocide |
Lipoxygenase; COX; Parasite | Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Diethylcarbamazine citrate (Caritrol) 是驱肠虫药,主要用作治疗丝虫病的柠檬酸盐,是丝虫微丝蚴的花生四烯酸代谢抑制剂。 | |||
T13810 |
Palmitoylcarnitine chloride
Palmitoyl DL-carnitine chloride |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) 是一种线粒体脂肪酸氧化中间体,可介导脂质内心脏保护。Palmitoylcarnitine chloride 通过消耗谷胱甘肽来消除结直肠癌细胞的存活,诱导癌细胞死亡,调节蛋白激酶 C βII 与其受体 RACK1 之间的相互作用。 | |||
T6708 |
Tolcapone
Tasmar,Ro 40-7592,托卡朋 |
Apoptosis; Beta Amyloid; Transferase | Apoptosis; Metabolism; Neuroscience |
Tolcapone (Ro 40-7592) 是一种选择性,具有口服活性的外周和中枢COMT 抑制剂,在肝脏中对 COMT 的IC50为 773 nM。它还是一种 α-syn 和 Aβ42 寡聚和原纤维形成的有效抑制剂,可诱导氧化应激导致神经母细胞瘤细胞凋亡和抑制肿瘤生长。 | |||
T11740 |
Delcasertib
KAI-9803,BMS-875944 |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Delcasertib (KAI-9803) 是一种有效且选择性的 δ-蛋白激酶 C (δPKC) 抑制剂,可改善急性心肌梗死动物模型的缺血再灌注损伤。 | |||
T83979 |
Sulcardine 2HCl
Sulcardine 2HCl(343935-60-4 Free base),HBI-3000 2HCl |
HER; Sodium Channel | Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors |
Sulcardine 2HCl 是一种多离子通道阻滞剂,具有抗心律失常作用,可阻断 hERG 和hNav1.5通道的特性,可用于研究心房颤动和室性心律失常。 | |||
T12356 |
Palmitoylcarnitine
Palmitoyl DL-carnitine |
Endogenous Metabolite | Metabolism |
Palmitoylcarnitine (Palmitoyl DL-carnitine) 是一种线粒体脂肪酸氧化中间体,可作为表面活性剂。 | |||
T126332 | 9-Phenylcarbazole | ||
9-Phenylcarbazole 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126332,CAS号为 1150-62-5。 | |||
TNU0954 | 3-Cyanovinylcarbazole | ||
Heterocyclic Compounds - Fused polyheterocycles | |||
T73752 | Glutarylcarnitine lithium | ||
Glutarylcarnitine lithium 丙二酸尿症和 I 型戊二酸尿症的重要诊断代谢物。 | |||
T33129 |
m-(1-Methylbutyl)phenyl methylcarbamate
|
||
m-(1-Methylbutyl)phenyl methylcarbamate is a bioactive chemical. | |||
T35017 |
Valeranilide, 2,2-dimethyl-3'-hydroxy-, tert-butylcarbamate (ester)
|
||
Valeranilide, 2,2-dimethyl-3'-hydroxy-, tert-butylcarbamate (ester) is a bioactive chemical. | |||
T11243 |
Ethyl tosylcarbamate
|
Others | Others |
Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Ethyl tosylcarbamate is an intermediate in the synthesis of Gliclazide (G409877). | |||
T20825 |
Diethylcarbamazine
RP3799,Diaethylcarbamazinum,AI3-19612,RP 3799,Bitirazine,RP-3799 |
||
Diethylcarbamazine, an anthelmintic, is used primarily as the citrate in the treatment of filariasis, particularly infestations with Loa loa or Wucheria bancrofti. | |||
T31620 |
Emylcamate
Emilcamato,Restetal,Nuncital,Psicoplegil,Emylcamat |
||
Emylcamate is an anxiolytic and muscle relaxant. It was advertised for the treatment of anxiety and tension. | |||
T74188 |
3-Cyanovinylcarbazole phosphoramidite
|
||
3-Cyanovinylcarbazole phosphoramidite 是一种抗病毒活性分子,可以抑制病毒 DNA 的合成。该化合物中的修饰核苷是通过在 C-3 位用氰基修饰核糖核苷酸而合成的,可作为 DNA 合成的磷酸酰胺。 | |||
T33553 |
N-(Diethylphosphorothioyl)-N-methylcarbamic acid, m-isopropylphenyl ester
|
||
N-(Diethylphosphorothioyl)-N-methylcarbamic acid, m-isopropylphenyl ester is a bioactive chemical. | |||
TNU0794 |
N2-acetyl-O6-(diphenylcarbamoyl)guanine
|
||
N2-acetyl-O6-(diphenylcarbamoyl)guanine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 TNU0794,CAS号为 112 233-74-6。 | |||
T35214 |
Xylylcarb
V-17004,S 1042,S-1042,V 17004,S1042 |
||
Xylylcarb is a biochemical. | |||
T30735 |
Carbanilic acid, m-hydroxy-N-methyl-, methyl ester, dimethylcarbamate (ester)
|
||
Carbanilic acid, m-hydroxy-N-methyl-, methyl ester, dimethylcarbamate (ester) is a bioactive chemical. | |||
T25033 |
Alcaftadine carboxylic acid
|
||
Alcaftadine is a novel antihistamine for preventing allergic conjunctivitis. | |||
T17703 |
Bromoacetamido-PEG9-ethylcarbamoyl-C4-Boc
|
Others | Others |
Bromoacetamido-PEG9-ethylcarbamoyl-C4-Boc is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, used for synthesizing PROTACs[1]. | |||
T35018 |
2-Chloro-3'-(methylcarbamoyloxy)valeranilide
Valeranilide, 2-chloro-3'-hydroxy-, methylcarbamate (ester) |
||
Valeranilide, 2-chloro-3'-hydroxy-, methylcarbamate (ester) is a bioactive chemical. | |||
T30734 |
Methyl m-hydroxycarbanilate, methylcarbamate
Carbanilic acid, m-hydroxy-, methyl ester, methylcarbamate |
||
Carbanilic acid, m-hydroxy-, methyl ester, methylcarbamate is a bioactive chemical. | |||
T39180 |
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride |
||
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker commonly employed for PROTAC synthesis. | |||
T37299 | L-Palmitoylcarnitine chloride | ||
Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine . In cells, palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 μM. In vivo, palmitoyl-L-carnitine increases intestinal absorption of the ant... | |||
T10119 |
3-O-Methyltolcapone
Ro 40-7591 |
Transferase | Metabolism |
3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for treatment of Parkinson's disease. | |||
T27804 | LCAHA | ||
LCAHA is a USP2a inhibitor. LCAHA inhibits growth of cyclin D1-dependent cells. | |||
T29598 |
Acetylcarnitine arginyl amide
ST-857,acetyl-L-carnitine arginine amide |
||
Acetylcarnitine arginyl amide is able to stimulate neurite outgrowth in a manner similar to that elicited by nerve growth factor (NGF). Neurite induction by this molecule requires de novo mRNA synthesis and is independent of the action of several common t | |||
T16093 |
Telcagepant
MK-0974 |
Others | Others |
Telcagepant is an orally active antagonist of calcitonin gene-related peptide (CGRP) receptor (Kis: 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively). | |||
T75403 | Glucuronokinase (AtGlcAK) | ||
Glucuronokinase (AtGlcAK) 为GHMP激酶家族的一员。其对D-葡萄糖醛酸表现出独有的底物特异性,具有0.7 mM的Km值。Glucuronokinase (AtGlcAK) 能催化D-葡萄糖醛酸与ATP反应生成D-葡萄糖醛酸-1-磷酸和ADP。 | |||
T66530 |
Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate
|
||
Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66530,CAS号为 1332524-01-2。 | |||
TP1235 |
Etelcalcetide
AMG 416,KAI-4169 |
||
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. | |||
T36205 |
Methylcarbamyl PAF C-16
|
||
Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its ability to induce platelet aggregation both in isolated platelets and in platelet-rich plasma. In NRK-49 cells overexpressing the PAF receptor, both PAF C-16 and methylcarbamyl PAF C-16 cause the induction of c-myc and c-fos and the activation of mitogen-activated protein kinase. Methy... | |||
T34897 |
Tolcaine HCl
MY 33-7,MY-33-7,Tolcaine hydrochloride,MY33-7 |
||
Tolcaine HCl is a bioactive chemical. | |||
T17704 |
Bromoacetamido-PEG9-ethylcarbamoyl-C8-Boc
|
Others | Others |
Bromoacetamido-PEG9-ethylcarbamoyl-C8-Boc represents a PEG-based PROTAC linker suitable for synthesizing PROTACs[1]. | |||
T30731 |
Carbanilic acid, m-hydroxy-, 2-methoxyethyl ester, methylcarbamate
|
||
Carbanilic acid, m-hydroxy-, 2-methoxyethyl ester, methylcarbamate is a bioactive chemical. | |||
T64409 |
1-(Phenylcarbamoyl)cyclopropanecarboxylic acid
|
||
1-(Phenylcarbamoyl)cyclopropanecarboxylic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64409,CAS号为 145591-80-6。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1040 |
Skullcapflavone II
|
COX; Antibacterial; TGF-beta/Smad | Immunology/Inflammation; Microbiology/Virology; Neuroscience; Stem Cells |
Skullcapflavone II 是从黄芩中提取的黄酮,具有抗炎作用。它对 M. aurum 和 M. bovisBCG 具有较强的抗菌活性。它还调节破骨细胞的分化、存活和功能。 | |||
T3742 |
3-Methylcatechol
3-甲基苯邻二酚,3-Methylpyrocatechol,2,3-Toluenediol,3-甲基邻苯二酚,2,3-dihydroxytoluene |
Others | Others |
3-Methylcatechol (2,3-Toluenediol) 是由 Pseudomonas putidaMC2 产生,能够用作化学合成中的分子砌块。 | |||
T5S1285 |
(+)-(3R,8S)-Falcarindiol
Falcarindiol,镰叶芹二醇 |
Others | Others |
(+)-(3R,8S)-Falcarindiol 是一种从胡萝卜中得到的聚乙炔,有抗炎、抗肿瘤和抗脂质过氧化活性。它具有抗分歧杆菌作用,对Mycobacterium tuberculosisH37Ra 的 MIC 和 IC50值分别为 24 μM 和 6 μM。 | |||
T2736 |
Sodium Demethylcantharidate
Sodium norcantharidin,去甲斑蝥酸钠 |
Others; Endogenous Metabolite | Metabolism; Others |
Sodium Demethylcantharidate (Sodium norcantharidin) 是内源性代谢产物的一种。 | |||
T12295 |
Oleoylcarnitine
Oleoyl-L-carnitine |
Endogenous Metabolite | Metabolism |
Oleoylcarnitine (Oleoyl-L-carnitine) 抑制腺嘌呤核苷酸转位酶 (AdNT) 活性,ic50为14 μM。Oleoylcarnitine 是检测神经分裂的重要指标。 | |||
T13280 |
Valerylcarnitine
VALERYL-L-CARNITINE |
Endogenous Metabolite | Metabolism |
Valerylcarnitine (VALERYL-L-CARNITINE) 是一种短链脂肪酸,可用于研究 2 型糖尿病。 | |||
TN1274 |
4-Allylcatechol
2-羟基胡椒酚,4-Allylpyrocatechol,Hydroxychavicol |
Others | Others |
4-Allylcatechol (Hydroxychavicol) 是合成黄樟素的一种中间体。 | |||
T64343 |
3-Methylcarbazole
NSC 10154 |
Others | Others |
3-Methylcarbazole (NSC-10154) 是具有抗癌作用的咔唑生物碱化合物。3-Methylcarbazole 对人纤维肉瘤 HT-1080 细胞具有生长抑制活性 (IC50 为 25 μg/mL)。 | |||
T4779 |
4-Methylcatechol
p-Methylcatechol,3,4-二羟基甲苯,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene |
Others; Endogenous Metabolite | Metabolism; Others |
4-Methylcatechol (3,4-Dihydroxytoluene) 是 p-toluate 的代谢物,它是 Catechol 2,3-Dioxygenase 的自杀性底物抑制剂。 | |||
T19340 |
Glutarylcarnitine
O-glutaroyl-L-carnitine |
Endogenous Metabolite | Metabolism |
Glutarylcarnitine (O-glutaroyl-L-carnitine) 是大多数串联质谱新生儿筛查计划中监测的丙二酸尿症和谷草酸尿症 I 型的诊断代谢物。 | |||
T3S1955 |
7-Ethylcamptothecin
|
Others | Others |
7-Ethylcamptothecin 是一种喜树碱类似物。其中喜树碱是一种细胞毒性生物碱,从喜树中分离出得到,对 L1210 白血病和 Walker 256 癌肉瘤模型具有很强的抗肿瘤活性。 | |||
T19398 |
L-Octanoylcarnitine
|
Endogenous Metabolite | Metabolism |
L-Octanoylcarnitine 是存在于血浆中的活性辛酰肉碱,是一种乳腺癌的潜在生物标志物。 | |||
T19384 |
Isovalerylcarnitine
|
Apoptosis; Cysteine Protease | Apoptosis; Proteases/Proteasome |
Isovalerylcarnitine (3-methylbutyrylcarnitine) 是 L-亮氨酸分解代谢和异戊酸的积累产生的小分子化合物,也是一种具有选择性和有效性的钙蛋白酶 (calpain) 激活剂,可促使细胞凋亡,与异戊酸血症有关,可作为异戊酸血症的标志。 | |||
TN6832 |
Sulcatone
6-甲基-5-庚烯-2-酮,6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one |
Endogenous Metabolite | Metabolism |
Sulcatone (6-Methyl-5-hepten-2-one) 是内源性代谢产物的一种。 | |||
T19564 |
Stearoylcarnitine
Stearoyl-L-carnitine |
Endogenous Metabolite | Metabolism |
Stearoylcarnitine (Stearoyl-L-carnitine) 是一种脂肪酯脂质分子,是一种人内源代谢产物,可作为早发型子痫前期和晚发性子痫前期的生物标志物。 | |||
TN7047 |
6-O-Methylcatalpol
|
Others | Others |
6-O-Methylcatalpol 是从 S. ningpoensis 的根中分离得到的天然产物。 | |||
T15157 |
Dodecanoylcarnitine
Lauroylcarnitine |
Endogenous Metabolite | Metabolism |
Dodecanoylcarnitine((-)-Lauroylcarnitine) 和脂肪酸氧化紊乱有关,使用 Dodecanoylcarnitine 可使鲑鱼降钙素的通透性增加。 | |||
T17048 |
Tetradecanoylcarnitine
L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine |
Endogenous Metabolite | Metabolism |
Tetradecanoylcarnitine (L-Myristoylcarnitine) 是一种酰基肉碱,参与长链脂肪酸的β-氧化,是极长链酰辅酶A脱氢酶缺乏症的一种潜在标记物。 | |||
TN2601 |
12-O-Methylcarnosic acid
|
Reductase | Endocrinology/Hormones; Metabolism |
12-O-Methylcarnosic acid 是分离自小叶丹参的丙酮提取物的一种二萜肉桂酸,可抑制 5α-还原酶 (5α-reductase) 活性,IC50为 61.7 μM。它抑制 LNCaP 细胞的增殖。它具有抗微生物活性、抗氧化和抗癌活性。 | |||
T14840 |
Butyrylcarnitine
|
Endogenous Metabolite | Metabolism |
Butyrylcarnitine 是血浆中的代谢物,是疾病引起异常代谢的指标,可用于诊断心力衰竭和胰腺囊肿。 | |||
T77563 |
4-Ethylcatechol
|
DNA | DNA Damage/DNA Repair |
4-Ethylcatechol 存在于红葡萄酒中,可从Glechoma longituba(NaKai)Kupr 中提取。4-Ethylcatechol 在Cu(II)存在下会引起DNA 损伤。4-Ethylcatechol 是一种高效的抗血小板化合物。 | |||
TN2360 |
Falcarinol
Falcarinol,Panaxynol,人参炔醇 |
HSP | Cytoskeletal Signaling; Metabolism |
Falcarinol, also known as Panaxynol, is a naturally occurring compound that acts as an orally active inhibitor of Hsp90. It effectively targets both the N-terminal and C-terminal regions of Hsp90, displaying high selectivity with minimal toxicities. Furthermore, Falcarinol (Panaxynol) demonstrates the ability to induce apoptosis. | |||
TN6217 |
3-Formylcarbazole
|
||
3-Formylcarbazole 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6217,CAS号为 51761-07-0。 | |||
TN5683 |
Ethyl 4-(rhamnosyloxy)benzylcarbamate
|
||
Ethyl 4-(rhamnosyloxy)benzylcarbamate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5683,CAS号为 208346-80-9。 | |||
T83467 |
10-O-Trans-p-methoxycinnamoylcatalpol
|
||
10-O-Trans-p-methoxycinnamoylcatalpol 表现出抗氧化特性,DPPH 自由基清除实验中显示其 IC50 为 0.37 μM/mL。 | |||
TN6253 |
7-Hydroxy-1-methoxy-3-methylcarbazole
|
||
7-Hydroxy-1-methoxy-3-methylcarbazole 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6253,CAS号为 107672-54-8。 | |||
T19391 |
L-Hexanoylcarnitine
|
Others | Others |
L-Hexanoylcarnitine is found to be associated with celiac disease, is an acylcarnitine. | |||
TN2574 | 10-O-Ethylcannabitriol | Others | Others |
10-O-Ethylcannabitriol is a natural product from Cannabis sativa L. | |||
T73764 | L-Palmitoylcarnitine TFA | ||
L-Palmitoylcarnitine TFA 是一种长链酰基肉碱和脂肪酸代谢产物,在缺血期间积聚于肌膜并扰乱膜脂环境。L-Palmitoylcarnitine TFA 通过与Kir6.2的相互作用抑制KATP 通道活性,而不影响单通道电导。 | |||
T72961 |
Falcarindiol
法卡林二醇 |
||
Falcarindiol 是一种口服活性聚乙炔氧脂,能激活 PPARγ 并增加 ABCA1 表达,具有诱导细胞凋亡和自噬的功能。此外,Falcarindiol 还展现出抗炎、抗菌、抗癌和抗糖尿病等特性。 | |||
TN3299 |
8alpha-Methacryloyloxy-13-ethoxyvernojalcanolide
|
Others | Others |
8alpha-Methacryloyloxy-13-ethoxyvernojalcanolide 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3299,CAS号为 142891-14-3。 | |||
TN3189 |
6'-O-p-Hydroxybenzoylcatalposide
|
Others | Others |
6'-O-p-Hydroxybenzoylcatalposide是一种天然产物,属于紫葳科梓属,其产品编号为 TN3189,CAS号为 355143-38-3。6'-O-p-Hydroxybenzoylcatalposide可用作对照参考。 | |||
TN5033 |
Skullcapflavone I
|
IL Receptor; Caspase; Prostaglandin Receptor | Apoptosis; GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome |
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se | |||
TN6210 |
N-Methoxy-3-formylcarbazole
|
||
N-Methoxy-3-formylcarbazole 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6210,CAS号为 117592-01-5。 | |||
TN1306 | 6-Feruloylcatalpol | Others | Others |
6-Feruloylcatalpol是一种天然产物,属于车前科胡黄连属,其产品编号为 TN1306,CAS号为 770721-33-0。6-Feruloylcatalpol可用作对照参考。 | |||
TN6190 |
N-Methoxy-3-hydroxymethylcarbazole
N-Methoxy-3-hydroxymethyl-9H-carbazole |
||
N-Methoxy-3-hydroxymethylcarbazole 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6190,CAS号为 142768-49-8。 | |||
TN3818 | Demethoxy-7-O-methylcapillarisin | Others | Others |
Demethoxy-7-O-methylcapillarisin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3818,CAS号为 61854-37-3。 | |||
T75637 | Demethylcantharidate disodium | ||
Demethylcantharidate disodium 是一种内源性代谢产物,能通过诱导内质网应激来促进肝癌细胞的凋亡,并且对多种类型的癌症展现出良好的抗癌活性。 | |||
TN3822 |
Demethylcarolignan E
|
Others | Others |
Demethylcarolignan E is a natural product from Hibiscus taiwanensis. | |||
T39107 |
5-O-(3'-O-Glucosylcaffeoyl)quinic acid
|
||
5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound primarily located in the leaves of Ilex glabra L. Gray (Aquifoliaceae). | |||
T83444 |
16-O-Methylcafestol
|
||
16-O-Methylcafestol为咖啡醇衍生物,可自生咖啡豆中提取。 | |||
TN3087 |
5,7,4'-Tri-O-methylcatechin
|
Others | Others |
5,7,4'-Tri-O-methylcatechin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3087,CAS号为 105330-59-4。 | |||
TN3190 |
6-O-p-Methoxycinnamoylcatalpol
|
Others | Others |
6-O-p-Methoxycinnamoylcatalpol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3190,CAS号为 121710-02-9。 | |||
TN6013 |
N-Methylcalycinine
|
||
N-Methylcalycinine exhibits potent AChE inhibitory activity. | |||
TN3185 | 6-O-Cinnamoylcatalpol | Others | Others |
6-O-Cinnamoylcatalpol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3185,CAS号为 136807-41-5。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05748 |
CD45 Protein, Human, Recombinant (aa 26-577, His)
L-CA,T200,LCA,B220,protein tyrosine phosphatase, re... |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPY-05308 |
CD45 Protein, Human, Recombinant (aa 1-529, His)
GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,... |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPK-00423 |
CD45 Protein, Human, Recombinant (His & Avi)
CD45R,LY5,EC 3.1.3.48,B220,CD45,T200,L-CA,GP180,LCA... |
Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. | |||
TMPK-00447 |
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3.... |
Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. | |||
TMPK-00424 |
CD45 Protein, Human, Recombinant (His & Avi), Biotinylated
LCA,LY5,EC 3.1.3.48,CD45,L-CA,T200,CD45R,PTPRC,B220... |
Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. | |||
TMPY-00711 |
CD45 Protein, Human, Recombinant (hFc)
GP180,L-CA,LY5,T200,protein tyrosine phosphatase, receptor t... |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPJ-00410 |
CD45R0 Protein, Human, Recombinant (His)
CD45 antigen,L-CA,protein tyrosine phosphatase, receptor typ... |
Human | Human Cells |
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor... | |||
TMPJ-00794 |
CD45 Protein, Mouse, Recombinant (His)
CD45,receptor-type tyrosine-protein phosphatase C,CD45R,L-CA... |
Mouse | Human Cells |
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor... | |||
TMPJ-00808 |
CD45RA Protein, Human, Recombinant (His)
PTPRC,CD45R,CD45,LCA,protein tyrosine phosphatase, ... |
Human | Human Cells |
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor... | |||
TMPY-03406 |
NMNAT1 Protein, Human, Recombinant (His)
PNAT1,LCA9,nicotinamide nucleotide adenylyltransfer... |
Human | Baculovirus-Insect Cells |
NMNAT, also known as NMNAT1, is a member of the Nicotinamide-nucleotide adenylyltransferases. It is widely expressed with high levels in skeletal muscle, heart, liver, and kidney. NMNAT appears to have the ability to protect against axonal degeneration following mechanical or toxic insults. The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT enz... | |||
TMPK-00709 |
Tulp1 Protein, Human, Recombinant (His)
LCA15,TUBL1,TULP1,RP14,Tubby-related protein 1,Tubb... |
Human | E. coli |
The tubby-like protein 1 (tulp1) gene is a member of the tubby multigene family which includes tub, tulp1, tulp2 and tulp3.TULP1 is a cytoplasmic, membrane-associated protein shown to be involved in transportation of newly synthesized proteins destined for the outer segment compartment of photoreceptor cells. | |||
TMPY-01578 |
CD166/ALCAM Protein, Human, Recombinant (His)
activated leukocyte cell adhesion molecule,CD166,MEMD |
Human | HEK293 |
Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-C... | |||
TMPJ-00339 |
ALCAM Protein, Mouse, Recombinant (hFc)
CD6 ligand,CD166 antigen,CD6L,activated leucocyte cell adhes... |
Mouse | Human Cells |
Activated leukocyte cell adhesion molecule (ALCAM), also named as CD166 and MEMD, is a typeI transmembrane glycoprotein of immunoglobulin superfamily, which mediates homotypic and heterotypic interactions between cells. ALCAM interacts with high affinity with CD6 molecule but weaker homotypic (ALCAM–ALCAM) interactions have also been described. ALCAM–CD6 interactions play an important role in the maintenance of T cell activation, proliferation as well as in formation of immune synapse between an... | |||
TMPY-03912 |
CD166/ALCAM Protein, Rat, Recombinant (hFc)
activated leukocyte cell adhesion molecule |
Rat | HEK293 |
Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-C... | |||
TMPK-00339 |
ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD6L,ALCAM,MEMD,KG-CAM,CD166 |
Mouse | HEK293 |
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. | |||
TMPH-01025 |
CALCA Protein, Human, Recombinant (GST)
Calcitonin gene-related peptide 1,CGRP-I,CALCA,CALC... |
Human | E. coli |
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. | |||
TMPY-00066 |
Procalcitonin/CALCA Protein, Human, Recombinant (His)
KC,CGRP,CALC1,Procalcitonin,CT,calcitonin-related polypeptid... |
Human | HEK293 |
Procalcitonin/CALCA Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 14.2 kDa. Accession number: P01258-1 | |||
TMPK-00678 |
CALCA/CGRP Protein, Mouse, Recombinant (hFc)
CGRP,Katacalcin,PDN-21,CGRP-I,CGRP1,Calcitonin 1,Calcitonin,... |
Mouse | HEK293 |
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 assay, and osteogenic differentiation with osteogenic staining, qPCR, and repair of calvarial defect. Furthermore, 5-azacytidine (5-az) was used to intervene ASCs-T2DM to verify the relationship between the methylation level of the target fragment and expression of Calca. | |||
TMPY-04120 |
Procalcitonin/CALCA Protein, Human, Recombinant (mFc)
Procalcitonin,CGRP,CGRP-I,calcitonin-related polypeptide α,C... |
Human | HEK293 |
Procalcitonin/CALCA Protein, Human, Recombinant (mFc) is expressed in HEK293 with mFc tag. The predicted molecular weight is 39.2 kDa. Accession number: P01258-1 | |||
TMPY-05484 |
CD166/ALCAM Protein, Human, Recombinant (hFc)
MEMD,activated leukocyte cell adhesion molecule,CD166 |
Human | HEK293 |
Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-C... | |||
TMPK-00835 |
LCAT Protein, Mouse, Recombinant (His)
PAF acetylhydrolase,LCAT |
Mouse | HEK293 |
Lecithin:cholesterol acyltransferase (LCAT) is the only enzyme capable of esterifying cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradient between peripheral cells and extracellular acceptors, for a long time, LCAT has been considered as a key enzyme in reverse cholesterol transport. | |||
TMPY-02936 |
CD166/ALCAM Protein, Rat, Recombinant (His)
activated leukocyte cell adhesion molecule |
Rat | HEK293 |
Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-C... | |||
TMPH-00056 |
Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His)
ATX II,Delta-AITX-Avd1c,Toxin II,Delta-actitoxin-Avd1c,Neuro... |
Anemonia sulcata | Yeast |
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent at mammalian Nav1.1/SCN1A (EC(50)=6.01 nM) and Nav1.2/SCN2A (EC(50)=7.88 nM). It has also great activity on Nav1.5/SCN5A (EC(50)=49.05 nM), Nav1.4/SCN4A (EC(50)=109.49 nM) and Nav1.6/SCN8A (EC(50)=about 180 nM) and is less potent on Nav1.3/SCN3A (EC(50)=759.22 nM) (when measured... | |||
TMPH-00058 |
asFP595 Protein, Anemonia sulcata, Recombinant (hFc)
GFP-like non-fluorescent chromoprotein FP595,asFP595 |
Anemonia sulcata | HEK293 |
Pigment protein that is intensely purple in color. | |||
TMPY-01031 |
CD166/ALCAM Protein, Mouse, Recombinant (His & hFc)
CD166,AI853494,MuSC,DM-GRASP,BEN,activated leukocyte cell ad... |
Mouse | HEK293 |
Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-C... | |||
TMPK-00340 |
ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated
CD166,CD6L,KG-CAM,ALCAM,MEMD |
Human | HEK293 |
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. | |||
TMPY-03520 |
CD166/ALCAM Protein, Cynomolgus, Recombinant (His)
activated leukocyte cell adhesion molecule |
Cynomolgus | HEK293 |
Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-C... | |||
TMPY-00055 |
LCAT Protein, Human, Recombinant (His)
lecithin-cholesterol acyltransferase |
Human | HEK293 |
Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradient between peripheral cells and extracellular acceptors, for a long time, LCAT has been considered as a key enzyme in reverse cholesterol transport. Lecithin cholesterol acyltransferase (LCAT) plays a pivotal role in HDL metabolism.LCAT is intimately involved in HDL maturation an... | |||
TMPH-00057 |
asFP595 Protein, Anemonia sulcata, Recombinant (GST)
GFP-like non-fluorescent chromoprotein FP595,asFP595 |
Anemonia sulcata | E. coli |
Pigment protein that is intensely purple in color. | |||
TMPK-00341 |
ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
ALCAM,KG-CAM,MEMD,CD166,CD6L |
Human | HEK293 |
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. | |||
TMPY-01153 |
CD166/ALCAM Protein, Mouse, Recombinant (His)
MuSC,CD166,SC1,activated leukocyte cell adhesion molecule,DM... |
Mouse | HEK293 |
Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-C... | |||
TMPY-00249 |
CD166/ALCAM Protein, Cynomolgus, Recombinant (hFc)
activated leukocyte cell adhesion molecule |
Cynomolgus | HEK293 |
Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-C... |