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Search Results for " gmp-1 "

Targets Recommended: IRAK cGAS

17

抑制剂 & 化合物

2

天然产物

1735

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T11673	IRAK4-IN-4	IRAK; cGAS	Immunology/Inflammation; NF-κB
	IRAK4-IN-4 （化合物 15）是白介素-1 受体相关激酶抑制剂，IC50为 2.8 nM。它还抑制环 GMP-AM 合酶，IC50为 2.1 nM。
T31020	CP 461 OSI 461,UNII-68OJX9I7DT,CP-461,CP461	Apoptosis; PDE	Apoptosis; Metabolism
	CP 461 (UNII-68OJX9I7DT) 是一种特异性 PDE2A 抑制剂，是一种新型促凋亡化合物，能抑制环 GMP 磷酸二酯酶，但不能抑制环氧化酶-1 或-2。CP 461 在体外可抑制多种人类肿瘤细胞系的生长，并选择性地诱导癌细胞系而不是正常细胞凋亡。
T16344	NS-2028	Others; Guanylate cyclase	GPCR/G Protein; Others
	NS-2028 是一种高度选择性的可溶性鸟苷酸环化酶抑制剂。它抑制 3-吗啉代-sydnonimine 在人培养的脐静脉内皮细胞中形成环状 GMP，IC50为30mM。它抑制小鼠小脑匀浆和神经元 NO 合酶中的可溶性鸟苷酸环化酶活性，IC50分别为 17 和 20 mM。它可降低血管内皮生长因子诱导的血管生成和通透性。
T81407	Prepro-Atrial Natriuretic Factor (26-55) (human)
	Prepro-Atrial Natriuretic Factor (26-55) (human) 为促进肾皮质与髓质循环GMP水平上升的多肽，同时也增强肾腺苷酸环化酶的活性。
T37960	Guanylin(human) TFA
	Guanylin (human) TFA is a 15-amino acid peptide that serves as an endogenous activator of intestinal guanylate cyclase. This compound is primarily located in the gastrointestinal tract, where it regulates electrolyte and water transport in the intestinal and renal epithelia through a mechanism dependent on cyclic GMP. [1][2]
T80148	GRP (14-27) (human, porcine, canine)	Bombesin Receptor	GPCR/G Protein
	GRP (14-27) (human, porcine, canine) 表现为铃蟾肽受体配体。其特异性结合受到 GTP 和 GDP 的抑制作用，但 GMP 对此无影响。
T28391	PF-9404C PF9404C
	PF-9404C is the S-S diesteroisomer of a beta adrenergic receptors blocker with vasodilatory properties. PF9404C increased the formation of cyclic GMP from 3 pmol mg−1 protein in basal conditions, to 53 pmol mg−1 protein in 10 μM in rat aorta smooth muscle
T78858	cGAS-IN-1
	cGAS-IN-1（化合物C20）是一种黄酮类化合物，作为Cyclic GMP-AMP Synthase（cGAS）的抑制剂，其IC50分别为2.28 μM（针对人类cGAS）和1.44 μM（针对小鼠cGAS）。由于cGAS异常激活与众多免疫介导的炎症性疾病相关，cGAS-IN-1显示出了其抗炎潜力。
T73609	Ribonuclease T1
	Ribonuclease T1 (Rnase T1)，常用于生化研究。Ribonuclease T1 是一种内切酶，可特异性降解单链 RNA。Ribonuclease T1 能够形成核苷 2′，3′-环磷酸中间体，以切割 3′-鸟苷残基与邻近核苷 5′-OH 基团之间的磷酸二酯键，产生 3′-GMP 末端寡核苷酸。
T38328	CU-32
	CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also selective for cGAS over toll-like receptors (TLRs) at 50 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas...
T38329	CU-76
	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas, R., Sun, L., Anderson, R., et al.Discovery of small-molecule cyclic GMP-AMP sy...
T40895	Calmodulin antagonist-1
	Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.
T36985	Cyclic di-UMP (sodium salt)
	Cyclic di-UMP is a pyrimidine-containing cyclic dinucleotide (CDN).1It is produced by bacterial cGAS/DncV-like nucleotidyltransferases (CD-NTases), such as LpCdnE02 fromL. pneumophila, and binds to cGAS, in the apo or dsDNA-bound forms, with reduced affinity compared to 2'3'-cGAMP or 3'3'-cGAMP .1,2Cyclic di-UMP is intended for use as a negative control for cyclic di-GMP signaling. 1.Whiteley, A.T., Eaglesham, J.B., de Oliveira Mann, C.C., et al.Bacterial cGAS-like enzymes synthesize diverse nuc...
T82489	eIF4E-IN-6
	eIF4E-IN-6（化合物4b）是一种针对eIF4E设计的抑制剂，可阻止其与cap mRNA的结合，其化学结构为GMP类似物。该化合物在Caco-2、HepG-2和MCF-7细胞系中显示出细胞毒性效果，其IC50值分别约为31、27和21 μM。
T21705	8-CPT-Cyclic AMP (sodium salt)
	8-CPT-Cyclic AMP (8-CPT-cAMP) sodium 是环 AMP 依赖性蛋白激酶的选择性激活剂。 8-CPT-Cyclic AMP sodium 也是有效的环 GMP 特异性磷酸二酯酶(PDE VA)抑制剂，IC50为 0.9 μM。 8-CPT-Cyclic AMP sodium 还抑制 PDE III 和 PDE IV，IC50分别为 24 和 25 μM。8-CPT-Cyclic AMP sodium 对 Epac 具有非常高的亲和力，是一种有效的Epac 活化剂。
T37800	PF-04449613
	PF-04449613 is a phosphodiesterase 9A (PDE9A) inhibitor (IC50= 22 nM).1It is selective for PDE9A over PDE1C (IC50= >1,000 nM), as well as over a variety of other PDEs, inhibiting PDE2-8, -10, and -11 activity by less than 30% in a panel of enzymes, ion channels, and transporters at 1 μM but does inhibit the human dopamine transporter (DAT; Ki= 293 nM). PF-04449613 (0.1-100 mg/kg, s.c.) increases cerebrospinal fluid (CSF) levels of cyclic GMP (cGMP) in rats. Subcutaneous administration of PF-0444...
T35422	5'-pApA (sodium salt)
	5'-pApA is a linearized form of cyclic di-AMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).1,2,3,4It is a metabolite of cyclic di-AMP formedviahydrolysis by various phosphodiesterases (PDEs).55'-pApA is intended for use as a negative control for cyclic di-AMP signaling. 1.Burdette, D.L., Monroe, K.M., Sotelo-Troha, K., et al.STING is a direct innate immune sensor of cyclic-di-GMPNature478(7370)515-518(2011) 2.Parvatiyar...

化合物

Cat.No: T11673

Target: IRAK, cGAS

Cat.No: T31020

Synonym: OSI 461,UNII-68OJX9I7DT,CP-461,CP461

Target: Apoptosis, PDE

Cat.No: T16344

Target: Others, Guanylate cyclase

Prepro-Atrial Natriuretic Factor (26-55) (human)

Cat.No: T81407

Guanylin(human) TFA

Cat.No: T37960

GRP (14-27) (human, porcine, canine)

Cat.No: T80148

Target: Bombesin Receptor

Cat.No: T28391

Synonym: PF9404C

Cat.No: T78858

Ribonuclease T1

Cat.No: T73609

Cat.No: T38328

Cat.No: T38329

Calmodulin antagonist-1

Cat.No: T40895

Cyclic di-UMP (sodium salt)

Cat.No: T36985

Cat.No: T82489

8-CPT-Cyclic AMP (sodium salt)

Cat.No: T21705

Cat.No: T37800

5'-pApA (sodium salt)

Cat.No: T35422

Cat. No.	Product Name	Target	Signaling Pathways
T72243	Cyclic-di-GMP diammonium 5GP-5GP diammonium,c-di-GMP diammonium ; cyclic diguanylate diammonium ; 5GP-5GP diammonium,c-di-GMP diammonium,cyclic diguanylate diammonium
	Cyclic di-GMP (c-di-GMP) diammonium 是一种STING 激活剂和无处不在的第二信使，调节生物膜的形成、运动和各种细菌的毒力。
T73717	cGAMP diammonium
	cGAMP (Cyclic GMP-AMPP) diammonium 是一种内源性第二信使，通过触发干扰素的产生来响应胞浆 DNA。它通过激活干扰素基因刺激因子（STING），启动信号级联，进而导致I型干扰素及其他免疫介质的生成。

天然产物

Cyclic-di-GMP diammonium

Cat.No: T72243

Synonym: 5GP-5GP diammonium,c-di-GMP diammonium ; cyclic diguanylate diammonium ; 5GP-5GP diammonium,c-di-GMP diammonium,cyclic diguanylate diammonium

cGAMP diammonium

Cat.No: T73717

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01166	CGAS Protein, Human, Recombinant (His) Cyclic GMP-AMP synthase,cGAMP synthase,CGAS,h-cGAS,...	Human	E. coli
	CGAS Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-02391	SUMO1 Protein, Human, Recombinant (His) small ubiquitin-like modifier 1,SMT3C,SMT3,SMT3H3,U...	Human	E. coli
	Small ubiquitin-like modifier protein (SUMO) modification is a highly dynamic process, catalyzed by SUMO-specific activating (E1), conjugating (E2) and ligating (E3) enzymes, and reversed by a family of SUMO-specific proteases (SENPs). Small ubiquitin-like modifier 1 (SUMO1) is a member of the superfamily of ubiquitin-like proteins. Despite its structural similarity with ubiquitin, SUMO1 does not seem to play any role in protein degradation. SUMO1 plays an important role in modulation of NOX act...
TMPY-03332	PRTFDC1 Protein, Human, Recombinant (His) HHGP,PRTFDC1,phosphoribosyl transferase domain cont...	Human	E. coli
	PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease(LND). LND is a sever...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) AMPK, AMPK(α1, β1, γ1)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPK-00383	ACE2/ACEH Protein, Human, Recombinant (His & Avi) ACE2,ACE-2,ACEH	Human	HEK293 Cells
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-04346	PD-L2 Protein, Human, Recombinant (His) PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00861	IL-33 Protein, Human, Recombinant IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...	Human	E. coli
	IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His) FLK2,FLK-2,CD135,STK1,fms-related tyrosine...	Human	HEK293 Cells
	FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-01185	DR5/TRAIL R2 Protein, Human, Recombinant (His) KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His) thymic stromal lymphopoietin	Human	HEK293 Cells
	TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-06418	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) R-spondin 2,CRISTIN2	Human	HEK293 Cells
	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL	Human	E. coli
	FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-04939	LAG-3 Protein, Human, Recombinant LAG-3,lymphocyte-activation gene 3,CD223	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc) WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...	Human	HEK293 Cells
	TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-00947	VCAM-1 Protein, Human, Recombinant (hFc) INCAM-100,CD106,VCAM-1,vascular c...	Human	HEK293 Cells
	VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-04165	FGFR3 Protein, Human, Recombinant (His) JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-01744	ACVR2A Protein, Human, Recombinant (His) activin A receptor, type IIA,ACVR2,ACTRII	Human	HEK293 Cells
	ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1.
TMPY-03967	BTN3A3 Protein, Human, Recombinant (His) BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3	Human	HEK293 Cells
	BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-01949	CD19 Protein, Human, Recombinant (His) CD19 molecule,B4,CVID3	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-05208	PD-L1 Protein, Human, Recombinant CD274 molecule,PDCD1L1,PD-L1,PDL<...	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-03407	NQO1 Protein, Human, Recombinant (His) NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...	Human	E. coli
	NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-00853	IL-1RA Protein, Human, Recombinant DIRA,IL1RA,interleukin 1 receptor antagoni...	Human	E. coli
	IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01862	IL-4 Protein, Human, Recombinant Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF	Human	E. coli
	IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-04826	LILRB5/CD85c Protein, Human, Recombinant (His) leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C	Human	HEK293 Cells
	A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc) leucine rich repeat containing 15,LIB	Human	HEK293 Cells
	LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-00203	LOXL2 Protein, Mouse, Recombinant (His) 1110004B06Rik,4930526G1<...	Mouse	HEK293 Cells
	Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-00820	IgG1 Fc Protein, Human, Recombinant (C103S) Ighg1,IgG1 Fc	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-04104	LIF Protein, Human, Recombinant CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HILDA	Human	HEK293 Cells
	LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-03290	HGF Protein, Mouse, Recombinant hepatocyte growth factor (hepapoietin A,NK1,scatter...	Mouse	HEK293 Cells
	HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-02030	CD82 Protein, Human, Recombinant (His) CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) thyroid peroxidase,MSA,TPX,TDH2A	Human	Baculovirus Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-01894	SIGIRR Protein, Human, Recombinant (His) TIR8,single immunoglobulin and toll-interleukin 1 r...	Human	HEK293 Cells
	SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His) HHF5,CD220,insulin receptor	Human	HEK293 Cells
	Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His) D1S166E,tumor necrosis factor receptor sup...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His) W282,W264,CEA,CD66D,CGM1,MGC11987...	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-03531	PSGL-1/CD162 Protein, Human, Recombinant (His) selectin P ligand,PSGL-1,PSGL1,CD1	Human	HEK293 Cells
	PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
TMPY-01147	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) RSPO,CRISTIN3,R-spondin 1	Human	HEK293 Cells
	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-02813	ErbB4 Protein, Human, Rhesus, Recombinant (His) erb-b2 receptor tyrosine kinase 4	Human,Rhesus	HEK293 Cells
	ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-01851	CD73 Protein, Human, Recombinant (His) eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...	Human	HEK293 Cells
	CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-02245	SNAP-25 Protein, Human, Recombinant (His) synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ	Human	E. coli
	Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-02033	CD44 Protein, Human, Recombinant (His) CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...	Human	HEK293 Cells
	CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1.
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His) ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-01938	CD98 Protein, Human, Recombinant (His) 4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...	Human	HEK293 Cells
	CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01883	EPOR Protein, Human, Recombinant (His) erythropoietin receptor,EPO-R	Human	HEK293 Cells
	EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1.
TMPY-02525	RGMA Protein, Human, Recombinant (His) repulsive guidance molecule family member a,RGM	Human	HEK293 Cells
	RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-01281	ACVR2B Protein, Mouse, Recombinant (His) ActRIIB,activin A receptor, type IIB,4930516B21...	Mouse	HEK293 Cells
	ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-00978	Progranulin Protein, Human, Recombinant (His) PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...	Human	HEK293 Cells
	Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
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重组蛋白

CGAS Protein, Human, Recombinant (His)

Cat.No: TMPH-01166

Species: Human

Expression System: E. coli

SUMO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02391

Species: Human

Expression System: E. coli

PRTFDC1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03332

Species: Human

Expression System: E. coli

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04451

Species: Human

Expression System: Baculovirus Insect Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-02501

Species: Human

Expression System: HEK293 Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03745

Species: Human

Expression System: HEK293 Cells

ACE2/ACEH Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00383

Species: Human

Expression System: HEK293 Cells

PD-L2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04346

Species: Human

Expression System: HEK293 Cells

IL-33 Protein, Human, Recombinant

Cat.No: TMPY-00861

Species: Human

Expression System: E. coli

FLT3 Protein, Human, Recombinant (T227M, His)

Cat.No: TMPY-01247

Species: Human

Expression System: HEK293 Cells

DR5/TRAIL R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01185

Species: Human

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (R127A & R130S, His)

Cat.No: TMPY-05220

Species: Human

Expression System: HEK293 Cells

R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06418

Species: Human

Expression System: HEK293 Cells

FLT3 Ligand Protein, Human, Recombinant

Cat.No: TMPY-06873

Species: Human

Expression System: E. coli

LAG-3 Protein, Human, Recombinant

Cat.No: TMPY-04939

Species: Human

Expression System: HEK293 Cells

TIGIT Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04970

Species: Human

Expression System: HEK293 Cells

VCAM-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00947

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04165

Species: Human

Expression System: HEK293 Cells

ACVR2A Protein, Human, Recombinant (His)

Cat.No: TMPY-01744

Species: Human

Expression System: HEK293 Cells

BTN3A3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03967

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Human, Recombinant (His)

Cat.No: TMPY-01949

Species: Human

Expression System: HEK293 Cells

PD-L1 Protein, Human, Recombinant

Cat.No: TMPY-05208

Species: Human

Expression System: HEK293 Cells

NQO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03407

Species: Human

Expression System: E. coli

IL-1RA Protein, Human, Recombinant

Cat.No: TMPY-00853

Species: Human

Expression System: E. coli

IL-4 Protein, Human, Recombinant

Cat.No: TMPY-01862

Species: Human

Expression System: E. coli

LILRB5/CD85c Protein, Human, Recombinant (His)

Cat.No: TMPY-04826

Species: Human

Expression System: HEK293 Cells

LRRC15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04333

Species: Human

Expression System: HEK293 Cells

LOXL2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00203

Species: Mouse

Expression System: HEK293 Cells

IgG1 Fc Protein, Human, Recombinant (C103S)

Cat.No: TMPY-00820

Species: Human

Expression System: HEK293 Cells

LIF Protein, Human, Recombinant

Cat.No: TMPY-04104

Species: Human

Expression System: HEK293 Cells

HGF Protein, Mouse, Recombinant

Cat.No: TMPY-03290

Species: Mouse

Expression System: HEK293 Cells

CD82 Protein, Human, Recombinant (His)

Cat.No: TMPY-02030

Species: Human

Expression System: HEK293 Cells

Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

Cat.No: TMPY-02779

Species: Human

Expression System: Baculovirus Insect Cells

SIGIRR Protein, Human, Recombinant (His)

Cat.No: TMPY-01894

Species: Human

Expression System: HEK293 Cells

Insulin Receptor Protein, Human, Recombinant (long isoform, His)

Cat.No: TMPY-01146

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01827

Species: Human

Expression System: HEK293 Cells

CEACAM3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01850

Species: Human

Expression System: HEK293 Cells

PSGL-1/CD162 Protein, Human, Recombinant (His)

Cat.No: TMPY-03531

Species: Human

Expression System: HEK293 Cells

R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01147

Species: Human

Expression System: HEK293 Cells

ErbB4 Protein, Human, Rhesus, Recombinant (His)

Cat.No: TMPY-02813

Species: Human,Rhesus

Expression System: HEK293 Cells

CD73 Protein, Human, Recombinant (His)

Cat.No: TMPY-01851

Species: Human

Expression System: HEK293 Cells

SNAP-25 Protein, Human, Recombinant (His)

Cat.No: TMPY-02245

Species: Human

Expression System: E. coli

CD44 Protein, Human, Recombinant (His)

Cat.No: TMPY-02033

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (His)

Cat.No: TMPY-04348

Species: Human

Expression System: HEK293 Cells

CD98 Protein, Human, Recombinant (His)

Cat.No: TMPY-01938

Species: Human

Expression System: HEK293 Cells

EPOR Protein, Human, Recombinant (His)

Cat.No: TMPY-01883

Species: Human

Expression System: HEK293 Cells

RGMA Protein, Human, Recombinant (His)

Cat.No: TMPY-02525

Species: Human

Expression System: HEK293 Cells

ACVR2B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01281

Species: Mouse

Expression System: HEK293 Cells

Progranulin Protein, Human, Recombinant (His)

Cat.No: TMPY-00978

Species: Human

Expression System: HEK293 Cells

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