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162

抑制剂 & 化合物

30

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5445	2-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi	Others	Others
	2-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi 用作中间体。
T32039	HADA Hydrochloride HCC-Amino-D-alanine hydrochloride,HADA HCl	Autophagy	Autophagy
	HADA Hydrochloride (HCC-Amino-D-alanine hydrochloride) 是一种具有蓝色荧光的D 氨基酸 (λem~450 nm)。FDAAs 在肽聚糖 (PG) 合成位点有效地与多种细菌的 PGs 结合。HADA Hydrochloride 而用于在最小干扰下特异性和共价探测细菌的生长。
T10930	D-AP5 (R)-(-)-2-氨基-5-膦酰戊酸,D-APV,D-2-Amino-5-phosphonovaleric acid	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	D-AP5 (D-APV) 是一种选择性和竞争性NMDA 受体拮抗剂，Kd 为 1.4 μM。D-AP5 抑制 NMDA 受体的谷氨酸结合位点。
T50072	3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride	Others	Others
	3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride 用于多种化合物的合成。
T10165L	5-A-RU hydrochloride 5-Amino-6-(D-ribitylamino)uracil hydrochloride	Others	Others
	5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) 是细菌核黄素的中间体，可激活粘膜相关不变 T 细胞（MAIT）。5-A-RU 可用于研究乳腺癌和前列腺癌。
T24243	Kanosamine 3-Amino-3-deoxyglucose,3-氨基-3-脱氧-D-葡萄糖	Antifungal	Microbiology/Virology
	Kanosamine (3-Amino-3-deoxyglucose) 是一种由链霉菌产生的抗真菌剂。
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide 4-氨基-6-(三氟甲基)苯-1,3-二磺酰胺,4-Amino-6-(trifluoromethyl)benzene-1,3-d,2,4-Disulfamyl-5-trifluoromethylaniline,2-amino-4-trifluoromethyl-1,5-benzendisulfonamide	Carbonic Anhydrase	Metabolism
	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) 是一种碳酸酐酶抑制剂，用作潜在的抗肿瘤和抗青光眼药物。
T21281	Zolamide CL 5343,Tio-urasin,5-Amino-TDSNH2,乙酰唑胺杂质D	Others	Others
	Zolamide (CL 5343) 可用于预防高原反应和减轻症状。
T9537	N'-Nitro-D-arginine N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸	Others	Others
	N'-Nitro-D-arginine (N'-Nitro-D-arginine) 是一种砌块。
T35442	1-Amino-1-deoxy-D-fructose (hydrochloride)
	1-Amino-1-deoxy-D-fructose is an amino monosaccharide.1It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.2,3
T30855	CGP77675 CGP-77675,1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol,ZINC1488120,CGP 77675	EGFR; VEGFR; Bcr-Abl; Src	Angiogenesis; Cytoskeletal Signaling; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	CGP77675 (ZINC1488120) 是一种有效的选择性 Src 家族激酶抑制剂，IC50 为 5-20 和 40 nM，用于肽底物的磷酸化和纯化的 Src 的自磷酸化。 CGP77675 具有抗癌活性。
T15438	GSK3186899 3,3,3-trifluoro-N-[4-[[3-[(2R)-2-methylmorpholin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]amino]cyclohexyl]propane-1-sulfonamide,DDD-853651	Parasite	Microbiology/Virology
	GSK3186899 是 Cdc2 相关激酶 12 的抑制剂，对 L. donovani 的 EC50 为 1.4 μM。
T8746L	I-49 free base Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-,I-49	Raf	MAPK
	I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) 是一种新型苄氨基取代的吡啶并嘧啶酮，可作为 SOS1 抑制剂。
T13017	STL127705 Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione	DNA-PK; Others	DNA Damage/DNA Repair; Others; PI3K/Akt/mTOR signaling
	STL127705 (Compound L) 是一种有效的 Ku 70/80 异二聚体蛋白抑制剂，抑制 Ku70/80-DNA 相互作用，IC50 为 3.5 μM。它抑制 Ku 依赖性 DNA-PKCS 激酶的激活，IC50 为 2.5 μM。
T29984	Aminoluciferin D-aminoluciferin,aLuc,Aminoluciferin[firefly],6-Amino-D-luciferin
	Aminoluciferin is a fluorescein derivative that can be used as a functional bioluminescence substrate.
T10165	5-A-RU 5-Amino-6-(D-ribitylamino)uracil	Others	Others
	5-A-RU (5-Amino-6-(D-ribitylamino)uracil), a precursor of bacterial Riboflavin, is a mucosal-associated invariant T (MAIT) cells activator. 5-A-RU forms potent MAIT-activating antigens via non-enzymatic reactions with small molecules that are derived from
T76170	D-Amino acid oxidase
	D-Amino acid oxidase 是一种酶，主要负责在动物体内代谢外源性 D-氨基酸以进行解毒，并能够调节大脑中D-丝氨酸的水平。
T19258	DL-3-Indolylglycine D,L-3-吲哚甘氨酸,α-Amino-1H-indole-3-acetic acid,D,L-3-Indolylglycine	Others	Others
	D, L-3-indolylglycine is an unnatural amino acid very similar to tryptophan, and its indole portion is directly connected to the α-position. Target: D, L-3-indolyl glycine can be used for functional protein design. One study described the inclusion of sim
T7476	AS057278 3-Methylpyrazole-5-carboxylic acid,5-甲基-1H-吡唑-3-羧酸	Others	Others
	AS057278 (3-Methylpyrazole-5-carboxylic acid) 是一种 D-氨基酸氧化酶 (DAAO) 抑制剂。
T69085	Mabuterol, (S)-
	Mabuterol, (S)- is a D isoform of Mabuterol, which is a selective β2 adrenoreceptor agonist. Mabuterol has been found to decrease the blood pressure in rats and increase heart rate and contractile force in guinea pigs. Mabuterol inhibited the positive inotropic effect of isoprenaline but has no effect on alpha-adrenergic, acetylcholine and histamine receptors.
T8721	I-37 Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-	Raf	MAPK
	I-37 (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-) 是一种新型苄氨基取代的吡啶并嘧啶酮，可作为 SOS1 抑制剂。
TNU0053	2-Amino-9-β-D-ribofuranosylpurine
	Nucleoside - 6-deaminopurine nucleoside
TNU1019	6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine
	6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU1018	6-Amino-4-chloropyrazolo[3,4-d]pyrimidine
	6-Amino-4-chloropyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU0268	2’-Amino-2’-deoxy-b-D-arabinouridine
	Nucleoside Derivatives - Amino-nucleoside; Arabino-nucleoside; 2’-Modified nucleoside
T75075	4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide
	4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要针对惰性淋巴系统恶性肿瘤。其作用机制包括抑制DNA合成和诱导细胞凋亡(apoptosis)。
TNU0321	6-Amino-4-methoxy-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	Nucleoside Derivatives - 7-deaza-8-aza purine nucleosides; 6-Modified purine nucleosides; Scaffolds and Templates
TNU0272	4-Amino-1-(b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide
	Nucleoside Derivatives - 7-Deaza-purine nucleosides; Natural product; inhibitor of protein kinase C 蛋白激酶抑制剂
TNU0279	6-Amino-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
	Nucleoside Derivatives - 7-Deaza-8-aza-purine nucleosides,6-Modified purine nucleosides; Scaffolds and Templates
TNU0385	1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine
	1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside; 8-Modified purine nucleoside; Amino nucleoside.
TNU0611	4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine
	Heterocyclic compound –purines, intermediate and building block; Used for modified nucleosides and nucleic acids
TNU0324	6-Amino-4-hydrozino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-hydrozino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU0324。
TNU0325	6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU0325。
T75044	6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine 是嘌呤核苷类似物，具有广泛的抗肿瘤活性，特别针对惰性淋巴系统的恶性肿瘤。其抗癌作用机制主要通过抑制 DNA 合成和诱导细胞凋亡(apoptosis)实现。
T75045	6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine 是嘌呤核苷类似物，具备抗肿瘤活性，主要针对惰性淋巴系统恶性肿瘤。其机制通过抑制DNA合成及诱导细胞凋亡(apoptosis)发挥作用。
T75041	6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要靶向惰性淋巴系统恶性肿瘤。其作用机制涉及抑制 DNA 合成和诱导细胞凋亡(apoptosis)。
TNU0271	4-Amino-5-cyano-1-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine
	Nucleoside Derivatives - 7-Deaza-purine nucleosides; Scaffolds and Templates
TNU1427	6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine
	6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine is a Nucleoside Derivative - Other modified nucleoside.
TNU0491	2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine
	2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside.
TNU0492	2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine
	2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside.
TNU0501	2’-Amino-2’-deoxy-b-D-arabino-5-methyl uridine
	Nucleoside Derivatives - 2’-Modified nucleosides; Amino nucleosides
T75185	6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine 是一种嘧啶核苷类似物，以其广泛的生化功能和抗癌活性著称，其机制涉及DNA合成抑制、RNA合成抑制、抗病毒和免疫调节等多方面。
TNU0322	6-Amino-2,5-dihydro-2-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one
	6-Amino-2,5-dihydro-2-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one is a Nucleoside Derivative - 7-deaza-8-aza purine nucleoside.
T75184	4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
	4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine 是一种嘧啶核苷类似物，具有广泛的生化作用和抗癌活性。这些活性包括抑制DNA合成、抑制RNA合成、抗病毒以及免疫调节等。
TNU0281	6-Amino-3-iodo-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
	Nucleoside Derivatives - 7-Deaza-8-aza purine nucleosides; Halo-nucleosides; 6-Modified purine nucleosides
TNU0757	2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside
	2-Amino-6-chloropurine-9-beta-D-(2'-deoxy)riboside is a 2'-Deoxy nucleoside; Halo-nucleoside.
TNU0389	6-Amino-3-ethynyl-4-methoxy-1-(b-D-ribofuranosyl)-1H- pyrazolo[3,4-d]pyrimidine
	6-Amino-3-ethynyl-4-methoxy-1-(b-D-ribofuranosyl)-1H- pyrazolo[3,4-d]pyrimidine is a Nucleoside Derivative - 8-Aza-7-deaza-purine nucleoside; 6-Modified purine nucleoside.
TNU1044	6-Amino-4-hydroxyamino-1-(2-deoxy-b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-hydroxyamino-1-(2-deoxy-b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1044。
T75187	6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine 是一种具有广泛生化作用和抗癌活性的嘧啶核苷类似物。这些活性包括 DNA 合成抑制、RNA 合成抑制、抗病毒作用和免疫调节作用。
TNU1034	4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
	4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside, 8-Modified-purine nucleoside, Halo-nucleoside; Scaffold and Template.

化合物

2-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi

Cat.No: T5445

Target: Others

HADA Hydrochloride

Cat.No: T32039

Synonym: HCC-Amino-D-alanine hydrochloride,HADA HCl

Target: Autophagy

Cat.No: T10930

Synonym: (R)-(-)-2-氨基-5-膦酰戊酸,D-APV,D-2-Amino-5-phosphonovaleric acid

Target: NMDAR, iGluR

3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride

Cat.No: T50072

Target: Others

5-A-RU hydrochloride

Cat.No: T10165L

Synonym: 5-Amino-6-(D-ribitylamino)uracil hydrochloride

Target: Others

Cat.No: T24243

Synonym: 3-Amino-3-deoxyglucose,3-氨基-3-脱氧-D-葡萄糖

Target: Antifungal

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

Cat.No: T9323

Synonym: 4-氨基-6-(三氟甲基)苯-1,3-二磺酰胺,4-Amino-6-(trifluoromethyl)benzene-1,3-d,2,4-Disulfamyl-5-trifluoromethylaniline,2-amino-4-trifluoromethyl-1,5-benzendisulfonamide

Target: Carbonic Anhydrase

Cat.No: T21281

Synonym: CL 5343,Tio-urasin,5-Amino-TDSNH2,乙酰唑胺杂质D

Target: Others

N'-Nitro-D-arginine

Cat.No: T9537

Synonym: N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸

Target: Others

1-Amino-1-deoxy-D-fructose (hydrochloride)

Cat.No: T35442

Cat.No: T30855

Synonym: CGP-77675,1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol,ZINC1488120,CGP 77675

Target: EGFR, VEGFR, Bcr-Abl, Src

Cat.No: T15438

Synonym: 3,3,3-trifluoro-N-[4-[[3-[(2R)-2-methylmorpholin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]amino]cyclohexyl]propane-1-sulfonamide,DDD-853651

Target: Parasite

Cat.No: T8746L

Synonym: Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-,I-49

Target: Raf

Cat.No: T13017

Synonym: Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione

Target: DNA-PK, Others

Aminoluciferin

Cat.No: T29984

Synonym: D-aminoluciferin,aLuc,Aminoluciferin[firefly],6-Amino-D-luciferin

Cat.No: T10165

Synonym: 5-Amino-6-(D-ribitylamino)uracil

Target: Others

D-Amino acid oxidase

Cat.No: T76170

DL-3-Indolylglycine

Cat.No: T19258

Synonym: D,L-3-吲哚甘氨酸,α-Amino-1H-indole-3-acetic acid,D,L-3-Indolylglycine

Target: Others

Cat.No: T7476

Synonym: 3-Methylpyrazole-5-carboxylic acid,5-甲基-1H-吡唑-3-羧酸

Target: Others

Mabuterol, (S)-

Cat.No: T69085

Cat.No: T8721

Synonym: Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-

Target: Raf

2-Amino-9-β-D-ribofuranosylpurine

Cat.No: TNU0053

6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine

Cat.No: TNU1019

6-Amino-4-chloropyrazolo[3,4-d]pyrimidine

Cat.No: TNU1018

2’-Amino-2’-deoxy-b-D-arabinouridine

Cat.No: TNU0268

4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide

Cat.No: T75075

6-Amino-4-methoxy-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0321

4-Amino-1-(b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide

Cat.No: TNU0272

6-Amino-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0279

1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine

Cat.No: TNU0385

4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0611

6-Amino-4-hydrozino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0324

6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0325

6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

Cat.No: T75044

6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

Cat.No: T75045

6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

Cat.No: T75041

4-Amino-5-cyano-1-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine

Cat.No: TNU0271

6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine

Cat.No: TNU1427

2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine

Cat.No: TNU0491

2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine

Cat.No: TNU0492

2’-Amino-2’-deoxy-b-D-arabino-5-methyl uridine

Cat.No: TNU0501

6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: T75185

6-Amino-2,5-dihydro-2-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one

Cat.No: TNU0322

4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Cat.No: T75184

6-Amino-3-iodo-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0281

2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside

Cat.No: TNU0757

6-Amino-3-ethynyl-4-methoxy-1-(b-D-ribofuranosyl)-1H- pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0389

6-Amino-4-hydroxyamino-1-(2-deoxy-b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU1044

6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: T75187

4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine

Cat.No: TNU1034

Cat. No.	Product Name	Target	Signaling Pathways
TN7191	4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine 4-氨基-5-溴吡咯并[2,3-D]嘧啶,5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Others	Others
	4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine (5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine) 是一种海洋来源的天然产物，存在于Echinodictyum sp.。
T4871	D-Glucosamic acid D-氨基葡萄糖酸,2-Amino-2-deoxy-D-gluconic acid,D-Glucosaminic acid	Others; Endogenous Metabolite	Metabolism; Others
	D-Glucosamic acid (2-Amino-2-deoxy-D-gluconic acid) 是内源性代谢产物的一种。
T9143	D-Isoleucine (2R,3R)-2-Amino-3-methylpentanoic acid,D-异亮氨酸,(R)-Isoleucine	Others	Others
	D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) 是一种异亮氨酸立体异构体，是 Asc-1 反转运蛋白的选择性激活剂。它能够释放内源性 D-丝氨酸，提高海马 CA1-CA3 的长期增效作用。
TN1545	D-Tyrosine	Tyrosinase	Proteases/Proteasome
	D-Tyrosine，是酪氨酸的D异构体，通过抑制酪氨酸酶活性，作为黑色素合成的负向调节剂。此外，D-Tyrosine还能抑制生物膜的形成，并诱导生物膜的自我分散，同时不影响细菌的生长。
T4514	N-Acetyl-D-Glucosamine N-乙酰-D-氨基葡萄糖,NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,N-乙酰氨基葡萄糖,GlcNAc	Endogenous Metabolite	Metabolism
	N-Acetyl-D-Glucosamine (NAG) 是葡萄糖的单糖衍生物。
T10938	D-Kynurenine D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103	GPR; AhR; Endogenous Metabolite	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism
	D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。
T10933	D-Cysteine	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Cysteine 是一种大肠杆菌生长的有力抑制剂，是半胱氨酸的 D 型异构体。它由 D-氨基酸氧化酶介导产生 H2S，是一种对抗小脑共济失调的神经保护剂。 D-半胱氨酸可以抑制由变形链球菌和链球菌血红蛋白形成的两种生物膜的生长和致龋性。
TQ0273	Neopterin D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one,新蝶呤	Endogenous Metabolite	Metabolism
	Neopterin (D-(+)-Neopterin) 是三磷酸腺苷的一种分解产物，是细胞免疫系统激活的标志物。
T4709	(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride 盐酸 D-甘露糖胺,D-Mannosamine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride (D-Mannosamine hydrochloride) 是内源性代谢产物的一种。
T2941	Glucosamine hydrochloride Chitosamine hydrochloride,盐酸氨基葡萄糖,2-Amino-2-deoxy-glucose HCl,Chitosamine HCl,D-(+)-Glucosamine hydrochloride	Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite; Autophagy	Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; NF-κB
	Glucosamine hydrochloride (Chitosamine hydrochloride) 是软骨基质和滑液中糖胺聚糖的天然成分，常用作骨关节炎的治疗方法。它也是一种氨基糖，是糖基化蛋白和脂质生化合成的突出前体，用作膳食补充剂。
T19302	D(-)-2-Aminobutyric acid	Endogenous Metabolite	Metabolism
	D(-)-2-Aminobutyric acid 是一种 D-氨基酸氧化酶的底物。
TJO2795	D-Galacturonic acid hydrate D-(+)-Galacturonic acid,D-半乳糖醛酸	Others; Endogenous Metabolite	Metabolism; Others
	D-Galacturonic acid hydrate 是内源性代谢产物的一种。
T5302	(R)-pyrrolidine-2-carboxylic acid D-脯氨酸,D-Proline	Others; Endogenous Metabolite	Metabolism; Others
	(R)-pyrrolidine-2-carboxylic acid (D-Proline) 是天然氨基酸 L -脯氨酸的异构体。D -氨基酸在人类血浆和唾液中含量相对较高。这些氨基酸可能是细菌来源，但也有证据表明它们是通过氨基酸消旋酶活性内源性产生的。
T4806	H-D-Trp-OH D-Tryptophan,D-色氨酸	Others; Endogenous Metabolite	Metabolism; Others
	H-D-Trp-OH (D-Tryptophan) 是一种色氨酸的 D 型异构体。它偶尔也会在自然界多肽中被发现，如海洋毒肽。
T6468	D-glutamine	Mitophagy; Ferroptosis; Endogenous Metabolite; GluR; Autophagy	Apoptosis; Autophagy; Metabolism; Neuroscience
	D-Glutamine 是有细胞渗透性谷氨酰胺的 D 型立体异构体，是标准遗传密码编码的20种氨基酸之一。
T6608	NMDA N-甲基-D-天冬氨酸,N-Methyl-D-aspartic acid	Endogenous Metabolite; NMDAR; iGluR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	NMDA (N-Methyl-D-aspartic acid) 是一种氨基酸，作为 D-异构体，是谷氨酸受体的 NMDA 受体亚型的定义激动剂。
T0689	D-Phenylalanine	Endogenous Metabolite; Monocarboxylate transporter	Membrane transporter/Ion channel; Metabolism
	D-Phenylalanine 是一种苯丙氨酸的合成右旋异构体，可抑制Pseudoalteromonas sp.SC2014 的生物膜发育。
T4716	Pyrrole-2-carboxylic acid 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite	Metabolism
	Pyrrole-2-carboxylic acid (Minaline) 是一种天然生物碱类，从海洋细菌Pelomonas puraquaesp. Nov 中分离得到。
T4712	H-D-cis-Hyp-OH 顺式-4-羟基-D-脯氨酸,D-allo-Hydroxyproline,cis-4-Hydroxy-D-proline	Others; Endogenous Metabolite	Metabolism; Others
	H-D-cis-Hyp-OH (D-allo-Hydroxyproline) 是一种合成构象受限的 PNA 腺嘌呤单体的前体，能够用于 D-丙氨酸脱氢酶的特异性和动力学的研究。
T4811	D-Alanine D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid	Chloride channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	D-Alanine ((R)-Alanine) 是一种GlyR 和PMBA 的弱激动剂，其对GlyR 的EC50=9 mM。
T8394	D-Serine (R)-Serine,D-丝氨酸	Endogenous Metabolite; NMDAR; iGluR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	D-Serine ((R)-Serine) 是一种具有独特的神经递质特性的神经胶质-突触相互作用中涉及的内源性氨基酸，是 NMDA 谷氨酸受体的有效共激动剂。D-Serine 在主要的 NMDAR 依赖性过程中具有主要的调节作用，包括 NMDAR 介导的神经传递，神经毒性，突触可塑性和细胞迁移。
T1130	Gramicidin 短杆菌肽,Gramicidinum,Gramicidine,Gramicidina	MRP; Antibacterial; Antibiotic	Immunology/Inflammation; Microbiology/Virology
	Gramicidin (Gramicidine) 是一种抗菌肽。它通过组装成膜中的通道，增加其对阳离子的渗透性。
T6475	(±)-Carnitine chloride Monocamin,DL-Carnitine HCl,Bicarnesine,混旋肉碱盐酸盐,DL-Carnitine chloride	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	(±)-Carnitine chloride (Monocamin) 有D 和L 两种异构体。其中 L-carnitine 在脂肪酸的 β-氧化中起重要作用，也具有抗氧化作用和抗炎活性。
T8363	DL-Serine	PKM	Metabolism
	DL-Serine 是 D-丝氨酸和 L-丝氨酸的混合物，是一种基础代谢物。它具有抗病毒作用，能抑制烟草花叶病毒的增殖。
T4705	Aminoadipic acid DL-2-Aminoadipic acid,DL-2-氨基己二酸	Others; Endogenous Metabolite	Metabolism; Others
	Aminoadipic acid (DL-2-Aminoadipic acid) 是赖氨酸主要生化途径中的代谢物。它是赖氨酸和糖碱代谢的中间体。它拮抗由谷氨酸受体 N-甲基-D-天冬氨酸调节的神经兴奋特性。
T19117	3-Deoxyglucosone 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose	GPX; Glucagon Receptor	GPCR/G Protein; oxidation-reduction
	3-Deoxyglucosone(3-Deoxy-D-glucosone) 是美拉德反应和多元醇反应的中间体途径合成。3-Deoxyglucosone 与蛋白质氨基快速反应形成晚期糖基化末端蛋白 (AGEs)。3-Deoxyglucosone 可使谷胱甘肽过氧化物酶失活，可与低葡萄糖协同作用以增强 GLP-1 分泌，可以作为糖尿病生物学检测的标志物。
TN1003	DL-Alanine DL-2-Aminopropionic acid	Endogenous Metabolite	Metabolism
	DL-Alanine (DL-2-Aminopropionic acid) 是一种氨基酸，是L-和D-丙氨酸的外消旋化合物。DL-Alanine 与硝酸银水溶液一起用于纳米颗粒生成时常作为还原剂和封端剂。DL-Alanine 是一种甜味剂，可把它位与甘氨酸和糖精钠归为一类。DL-Alanine 在组织和肝脏之间的葡萄糖-丙氨酸循环中起重要作用。DL-Alanine 可用于研究 Cu、Zn、Cd 等过渡金属螯合。
T11201	Enniatin A1 恩镰孢菌素 A1	ERK	MAPK
	Enniatin A1 possesses anticarcinogenic properties by induction of apoptosis and disruption of ERK signalling pathway. Enniatin A1 inhibits ACAT with an IC50 of 49 μM in rat liver microsomes. Enniatin A1 isolated from Fusarium mycotoxins is a cyclic hexadepsipeptide consisting of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids.
T75890	Conantokin G TFA
	Conantokin G TFA 是一种 17 个氨基酸的肽，是一种有效，选择性和竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。Conantokin G TFA 抑制鼠皮质神经元中NMDA 诱发的电流，IC50为 480 nM，具有神经保护作用。
T80862	Vitamin B15 hemicalcium Pangamic Acid hemicalcium
	Vitamin B15 (Pangamic Acid) hemicalcium 是一种自然存在于植物种子中的化合物，具有促进细胞呼吸的作用。它包含了D-葡萄糖基二甲基氨基乙酸，并可作为免疫校正剂。Vitamin B15 hemicalcium 在多种疾病研究中有应用。

天然产物

4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine

Cat.No: TN7191

Synonym: 4-氨基-5-溴吡咯并[2,3-D]嘧啶,5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Target: Others

D-Glucosamic acid

Cat.No: T4871

Synonym: D-氨基葡萄糖酸,2-Amino-2-deoxy-D-gluconic acid,D-Glucosaminic acid

Target: Others, Endogenous Metabolite

Cat.No: T9143

Synonym: (2R,3R)-2-Amino-3-methylpentanoic acid,D-异亮氨酸,(R)-Isoleucine

Target: Others

Cat.No: TN1545

Target: Tyrosinase

N-Acetyl-D-Glucosamine

Cat.No: T4514

Synonym: N-乙酰-D-氨基葡萄糖,NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,N-乙酰氨基葡萄糖,GlcNAc

Target: Endogenous Metabolite

Cat.No: T10938

Synonym: D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103

Target: GPR, AhR, Endogenous Metabolite

Cat.No: T10933

Target: Endogenous Metabolite, Antibacterial

Cat.No: TQ0273

Synonym: D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one,新蝶呤

Target: Endogenous Metabolite

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

Cat.No: T4709

Synonym: 盐酸 D-甘露糖胺,D-Mannosamine hydrochloride

Target: Others, Endogenous Metabolite

Glucosamine hydrochloride

Cat.No: T2941

Synonym: Chitosamine hydrochloride,盐酸氨基葡萄糖,2-Amino-2-deoxy-glucose HCl,Chitosamine HCl,D-(+)-Glucosamine hydrochloride

Target: Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Autophagy

D(-)-2-Aminobutyric acid

Cat.No: T19302

Target: Endogenous Metabolite

D-Galacturonic acid hydrate

Cat.No: TJO2795

Synonym: D-(+)-Galacturonic acid,D-半乳糖醛酸

Target: Others, Endogenous Metabolite

(R)-pyrrolidine-2-carboxylic acid

Cat.No: T5302

Synonym: D-脯氨酸,D-Proline

Target: Others, Endogenous Metabolite

Cat.No: T4806

Synonym: D-Tryptophan,D-色氨酸

Target: Others, Endogenous Metabolite

Cat.No: T6468

Target: Mitophagy, Ferroptosis, Endogenous Metabolite, GluR, Autophagy

Cat.No: T6608

Synonym: N-甲基-D-天冬氨酸,N-Methyl-D-aspartic acid

Target: Endogenous Metabolite, NMDAR, iGluR

D-Phenylalanine

Cat.No: T0689

Target: Endogenous Metabolite, Monocarboxylate transporter

Pyrrole-2-carboxylic acid

Cat.No: T4716

Synonym: 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline

Target: Endogenous Metabolite

Cat.No: T4712

Synonym: 顺式-4-羟基-D-脯氨酸,D-allo-Hydroxyproline,cis-4-Hydroxy-D-proline

Target: Others, Endogenous Metabolite

Cat.No: T4811

Synonym: D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid

Target: Chloride channel, Endogenous Metabolite

Cat.No: T8394

Synonym: (R)-Serine,D-丝氨酸

Target: Endogenous Metabolite, NMDAR, iGluR

Cat.No: T1130

Synonym: 短杆菌肽,Gramicidinum,Gramicidine,Gramicidina

Target: MRP, Antibacterial, Antibiotic

(±)-Carnitine chloride

Cat.No: T6475

Synonym: Monocamin,DL-Carnitine HCl,Bicarnesine,混旋肉碱盐酸盐,DL-Carnitine chloride

Target: Reactive Oxygen Species

Cat.No: T8363

Target: PKM

Aminoadipic acid

Cat.No: T4705

Synonym: DL-2-Aminoadipic acid,DL-2-氨基己二酸

Target: Others, Endogenous Metabolite

3-Deoxyglucosone

Cat.No: T19117

Synonym: 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose

Target: GPX, Glucagon Receptor

Cat.No: TN1003

Synonym: DL-2-Aminopropionic acid

Target: Endogenous Metabolite

Cat.No: T11201

Synonym: 恩镰孢菌素 A1

Target: ERK

Conantokin G TFA

Cat.No: T75890

Vitamin B15 hemicalcium

Cat.No: T80862

Synonym: Pangamic Acid hemicalcium

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