113
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55
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T18468 |
N3-C5-NHS ester
叠氮-C5-琥珀酰亚胺酯 |
Others | Others |
N3-C5-NHS ester 是一种不可切割的 ADC 接头,用于合成抗体-药物偶联物。 | |||
T17548 |
Biotin-C5-amino-C5-amino
|
Others; PROTAC Linker | Others; PROTAC |
Biotin-C5-amino-C5-amino 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T15146 |
DNA2 inhibitor C5
|
Others | Others |
DNA2 inhibitor C5 是竞争性特异性的DNA2 核酸酶活性抑制剂(IC50:20 μM)。它能够抑制DNA 依赖性 ATPase、 DNA2 的核酸酶、解旋酶和 DNA 结合活性。它可用于研究奥正癌症。 | |||
T9270 |
C5 Lenalidomide
来那度胺杂质13 |
Others | Others |
C5 Lenalidomide 是一种具有不确定生物活性的化学物质。 | |||
T10863 |
Complement C5-IN-1
|
Complement System | Immunology/Inflammation |
Complement C5-IN-1 (Compound 7) 是补体成分蛋白5 (C5) 的小分子抑制剂。 Complement C5-IN-1 与 C5 相互作用以防止其被 C5 转化酶切割, 阻断酵母多糖诱导的 50%人全血 MAC 沉积的 IC50 值为 0.77 μM。 | |||
T40007 |
Pomalidomide-C5-COOH
|
Others | Others |
Pomalidomide-C5-COOH 是一种合成的 E3 连接酶配体-接头偶联物,它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。 | |||
T18617 |
NH2-C5-NH-Boc
N-(5-氨基戊基)氨基甲酸叔丁酯,PROTAC Linker 23 |
Others; PROTAC Linker | Others; PROTAC |
NH2-C5-NH-Boc (PROTAC Linker 23) 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T39060 |
Benzyloxy-C5-PEG1
Benzyloxy-C5-PEG1 |
||
Benzyloxy-C5-PEG1 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T60500 |
AP-C5
|
Parasite | Microbiology/Virology |
AP-C5 是一种具有选择性抑制鸟苷3',5' 环一磷酸 (cGMP) 依赖性蛋白激酶 II (cGKII) 作用的化合物,对 cGMP 的 Pic50 值为 7.2,可用于研究腹泻疾病。 | |||
T39496 |
Thalidomide-O-C5-acid
Thalidomide-O-C5-acid |
||
Thalidomide-O-C5-acid is a chemically synthesized conjugate that acts as an E3 ligase ligand-linker and combines the cereblon ligand derived from Thalidomide with a linker commonly utilized in PROTAC technology. | |||
T38830 |
Modified MMAF-C5-COOH
Modified MMAF-C5-COOH |
||
Modified MMAF-C5-COOH is a drug-linker conjugate for ADC. | |||
T39900 |
Thalidomide-O-amide-C5-NH2
Thalidomide-O-amide-C5-NH2 |
||
Thalidomide-O-amide-C5-NH2 is a chemically synthesized conjugate, serving as an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide with a linker that is commonly employed in PROTAC technology. | |||
T39599 |
Lenalidomide-C5-amido-Boc
Lenalidomide-C5-amido-Boc |
||
Lenalidomide-C5-amido-Boc is a Cereblon ligand derived from Lenalidomide, and serves in the recruitment of CRBN protein. It can be effectively linked to the protein ligand through a linker, resulting in the formation of PROTAC. | |||
T61483 |
GLP-1R modulator C5
|
Glucagon Receptor | GPCR/G Protein |
GLP-1R modulator C5 是一种小分子 GLP-1R 正变构调节剂,通过跨膜位点增强GLP-1与GLP-1R的结合,可用于研究 II 型糖尿病。。 | |||
T39651 |
(S,R,S)-AHPC-C5-NH2
(S,R,S)-AHPC-C5-NH2,VH032-C5-NH2 |
||
(S,R,S)-AHPC-C5-NH2, also known as VH032-C5-NH2, is a synthetic compound designed as an E3 ligase ligand-linker conjugate. This compound combines the VH032-based von Hippel-Lindau (VHL) ligand with a linker, enabling it to function as a PROTAC degrader for estrogen-related receptor α (ERRα). | |||
T40079 |
Thalidomide-O-C5-NH2 hydrochloride
Thalidomide-O-C5-NH2 hydrochloride |
||
Thalidomide-O-C5-NH2 hydrochloride is a synthetic compound consisting of a ligand-linker conjugate with E3 ligase activity. It combines a cereblon ligand based on Thalidomide and a linker commonly utilized in PROTAC technology. | |||
T38999 |
Biotin-C4-amide-C5-NH2
Biotin-C4-amide-C5-NH2 |
||
Biotin-C4-amide-C5-NH2 is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs). | |||
T18667 |
(S,R,S)-AHPC-C5-COOH
VH032-C5-COOH |
Others | Others |
(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases[1]. | |||
T18307 |
MC(C5)-Val-Cit
|
Others | Others |
MC(C5)-Val-Cit is a cleavable ADC linker employed in ADCs synthesis [1]. | |||
T18638 |
Boc-C5-O-C5-O-C6-Cl
PROTAC Linker 2 |
Others | Others |
Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a chemical compound commonly employed as a linker in PROTAC applications. Its primary function is to connect a specific tyrosine kinase inhibitor (TKI) with the E3 recruiting ligand. | |||
T78421 |
Biotin-C5-Azide
DecarboxyBiotin-N3 |
||
Biotin-C5-Azide(DecarboxyBiotin-N3)是用于合成生物素标记偶联物的生物素衍生物。 | |||
T14576 | Biotin-C5-NHS Ester | Others | Others |
Biotin-C5-NHS Ester is an alkyl/ether-based linker for PROTAC synthesis[1]. | |||
T17928 |
Lenalidomide-C5-NH2
E3 ligase Ligand-Linker Conjugates 31,Cereblon Ligand-Linker Conjugates 19 |
Others | Others |
Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1]. | |||
T18063 |
Lenalidomide-acetylene-C5-COOH
Cereblon ligand-linker Conjugate |
Others | Others |
Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) serves as a Lenalidomide-based Cereblon ligand that facilitates the recruitment of the CRBN protein. This compound can be connected to the protein's ligand through a linker, resulting in the formation of PROTAC[1]. | |||
T36262 |
Thalidomide-NH-C5-NH2 hydrochloride
Pomalidomide 4'-alkylC5-amine |
||
Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 4 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T18489 |
NH2-O-C5-COOH hydrobromide
6-Aminooxy-hexanoic acid hydrobromide |
Others | Others |
NH2-O-C5-COOH (hydrobromide) is an alkyl chain-derived PROteolysis TArgeting Chimera (PROTAC) linker employed for PROTAC synthesis [1]. | |||
T18445 |
N-Methyl-N'-(azido-PEG2-C5)-Cy5
|
Others | Others |
N-Methyl-N'-(azido-PEG2-C5)-Cy5 is a polyethylene glycol (PEG)-based linker that incorporates an azide functionality. This linker is primarily utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1]. | |||
T125394 | Tetromycin C5 | ||
Tetromycin C5 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125394,CAS号为 205433-86-9。 | |||
T18486 |
NH2-C5-PEG4-N3-L-Lysine-PEG3-N3
|
Others | Others |
NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a seven-unit cleavable polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed in the synthesis of ADCs[1]. | |||
T18670 |
(S,R,S)-AHPC-Me-C5-COOH
|
Others | Others |
(S,R,S)-AHPC-Me-C5-COOH is a synthetic E3 ligase ligand-linker conjugate consisting of a VHL ligand and a linker. It finds application in PROTAC DT2216[1]. | |||
T18660 |
(S,R,S)-AHPC-amido-C5-acid
|
Others | Others |
(S,R,S)-AHPC-amido-C5-acid is a chemical compound that contains a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. It can be utilized in the design of XY028-133[1]. | |||
T9915 |
Eculizumab
|
Complement System | Immunology/Inflammation |
Eculizumab 是针对补体 C5 的长效人源化单克隆抗体。它对 C5 裂解为 C5a 和 C5b 具有抑制作用,并抑制了末端补体系统的部署,其中包括膜攻击复合物的形成。它可用于溶血的研究。 | |||
T81421 |
Pomalidomide-C5-Dovitinib
|
PROTACs | PROTAC |
Pomalidomide-C5-Dovitinib(compound 2)是链接Pomalidomide与Dovitinib的PROTAC,且与CRBN结合。该化合物在FLT3-ITD+ AML细胞中表现出增强的抗增殖能力,通过泛素-蛋白酶体依赖性途径促进FLT3-ITD和KIT蛋白的降解,并彻底抑制其下游信号传导,显示出研究FLT3-ITD+急性髓系白血病的潜力。 | |||
T17903 |
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH
E3 ligase Ligand-Linker Conjugates 49,Cereblon Ligand-Linker Conjugates 14 |
Others | Others |
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized compound, designed as an E3 ligase ligand-linker conjugate, integrating the cereblon ligand derived from Pomalidomide and a linker employed in PROTAC technology. This compound serves to facilitate targeted protein degradation through the modulation of E3 ligase activity, enabling the selective elimination of specific proteins of interest. | |||
T74727 | CL845-PAB-Ala-Val-C5-MC | ||
CL845-PAB-Ala-Val-C5-MC 是一种可结合的 STING 配体,由专有的环状二核苷酸 CL845 合成。CL845-PAB-Ala-Val-C5-MC 可用于生物偶联。 | |||
T77952 |
Thalidomide-5-O-C5-NH2 hydrochloride
|
||
Thalidomide-5-O-C5-NH2 hydrochloride是Thalidomide衍生的cereblon配体,能够招募CRBN蛋白。该化合物能透过linker与目标蛋白配体结合,用于构建PROTAC分子,如THAL-SNS-032。 | |||
T71022 |
GI-129471
|
||
GI-129471 is a metalloproteinase inhibitor, specifically blocking TNF-alpha secretion both in vitro and in vivo. | |||
T6910 |
NSC59984
|
p53 | Apoptosis |
NSC59984 是 p53 通路激活剂,可诱导突变 p53 蛋白降解和 p73 活化。它通过 MDM2 和泛素-蛋白酶体途径而诱导突变型 p53 蛋白降解。 | |||
T11147 |
EC5026
BPN-19186 |
Epoxide Hydrolase | Metabolism |
EC5026 (BPN-19186) 是首创的,非阿片类的,可溶性环氧水解酶 (sEH) 抑制剂,它可有效缓解发炎性和神经性疼痛。 | |||
T2242 |
Wnt-C59
4-(2-甲基-4-吡啶基)-N-[4-(3-吡啶基)苯基]苯乙酰胺,C59 |
Wnt/beta-catenin; Porcupine | Cytoskeletal Signaling; Stem Cells |
Wnt-C59 (C59) 是一种高效的、口服具有活力的PORCN 抑制剂(IC50:74 pM)。 | |||
T19000 |
HBC514
|
Others | Others |
HBC514 是一种非荧光 HBC 类似物,在与 Pepper RNA 适体形成紧密复合物后会发出强烈的绿色荧光。 | |||
T21876 |
DC_AC50
|
Apoptosis; Others | Apoptosis; Others |
DC_AC50 是一种 Atox 和 CCS 的双抑制剂,是一种抑制细胞内铜伴侣作为减少/预防获得性化疗耐药性的手段。它与 Atox1 和 CCS 结合并减少癌细胞增殖和肿瘤生长。 | |||
T21302 |
UNC569
UNC 569 |
TAM Receptor | Tyrosine Kinase/Adaptors |
UNC569 (UNC 569) 是一种ATP 竞争性的、可逆、具有口服活性的Mer 激酶抑制剂,其IC50=2.9 nM,Ki=4.3 nM。它还抑制Axl 和Tyro3,IC50分别为 37 nM 和 48 nM。它可用于研究急性淋巴细胞白血病和非典型畸胎瘤/横纹肌瘤。 | |||
T12860 |
SC57666
|
COX | Immunology/Inflammation; Neuroscience |
SC57666是一种具有高选择性的 COX2 抑制剂(IC50 值为26 nM),对COX1不显示活性。 | |||
T14852 |
C527
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
C527 是一种泛 DUB 酶抑制剂,对 USP1/UAF1 复合物具有高效力,IC50值为0.88 μM。 | |||
T12862 |
SC58451
|
COX | Immunology/Inflammation; Neuroscience |
SC58451 是一种新型有效且具有口服活性和选择性的 COX-2 抑制剂。SC58451在大鼠关节炎模型中显示出抗炎活性。 | |||
TP1648L |
[Gln8]-C517 (LH-RH), chicken acetate
[Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base) |
Others | Others |
[Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base) 是一种鸟类下丘脑肽,可刺激垂体前叶释放促性腺激素,从而调节生殖功能。 | |||
T9832 |
(Rac)-EC5026
Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-(2-methyl-1-oxobutyl)-4-piperidinyl]- |
Epoxide Hydrolase | Metabolism |
(Rac)-EC5026 ((Rac)-BPN-19186) 是一种有效的可溶性环氧水解酶 (sEH) 哌啶抑制剂,Ki 值为 0.06 nM。(Rac)-EC5026 可用于帕金森氏病和路易体痴呆 (DLB) 的研究。 | |||
T60937 | TRPC5-IN-1 | ||
TRPC5-IN-1是一种TRPC5抑制剂,在各种慢性肾病动物模型中均具有活性。 | |||
T64611 | Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R | ||
Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64611。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8240 |
Cis-5-Dodecenoic Acid
|
Others | Others |
Cis-5-Dodecenoic Acid 是一种单不饱和脂肪酸,具有 C12 链作为主链,C5 位具有顺式双键。 | |||
T1688 |
Pregnanediol
5Beta-Pregnane-3Alpha,20alpha-Diol,孕甾二醇,Pregnandiol,孕二醇 |
Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) 是一种黄体酮的主要代谢物 (metabolite),能够通过尿液排出。它提供了一种间接测定体内孕激素水平的方法。 | |||
T4794 |
Glutaric acid
|
Endogenous Metabolite | Metabolism |
Glutaric acid 是一种 C5 二羧酸,是色氨酸和赖氨酸分解代谢途径中的中间体。Glutaric acid 影响周细胞的收缩性和迁移。Glutaric acid 是 I 型戊二酸尿症的生物指标。 | |||
TN5930 |
Ocotillone
|
||
Ocotillone has potent antibacterial activity against Gram-negative bacteria, P. aeruginosa and S. typhimurium, that are without hemolytic activity, whereas it has weak antimicrobial activity against Gram-positive bacteria and fungi. Ocotillone shows only | |||
T81201 |
Sartorypyrone B
|
||
Sartorypyrone B为Chevalone C的2β-乙酰氧基衍生物,由海绵源真菌Neosartorya tsunodae(KUFC 9213)的培养物中乙酸乙酯提取得到。该化合物对MCF-7、NCI-H460和A375-C5细胞系展示出较强的生长抑制活性,GI50s值分别为17.8、20.5和25.0 μM,显示其在乳腺癌、非小细胞肺癌和黑色素瘤研究中的应用潜力。 | |||
T35754 |
Aszonapyrone A
|
||
Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.1,2,3 It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively).1 Aszonapyrone A is active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation.2 It is also active against P. falciparum in vitro (IC50 = 1.34... | |||
T38484 |
Englerin A
(-)-Englerin A |
TRP/TRPV Channel | Membrane transporter/Ion channel |
Englerin A 是一种具有选择性和高效性的 TRPC4 和 TRPC5 通道激动剂,是一种来自东非植物 Phyllanthus engleri 的小分子化合物,具有镇痛、抗炎和抗癌活性。Englerin A 可刺激 TRPC4/C5 阳离子通道以抑制肿瘤细胞系增殖,诱导人肾癌细胞坏死。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00653 |
Complement C5 Protein, Human, Recombinant (Complement C5a)
C5D,C5b,CPAMD4,complement component 5,Comp... |
Human | E. coli |
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is P01031. | |||
TMPY-05057 |
Complement C5 Protein, Human, Recombinant (His & FLAG)
C5b,ECLZB,C5a,CPAMD4,C5D,compleme... |
Human | HEK293 Cells |
Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 188.8 kDa and the accession number is P01031. | |||
TMPH-03270 |
Complement C5 Protein, Rat, Recombinant (His & Myc)
Complement C5,C5 |
Rat | E. coli |
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.0 kDa and the accession number is P08650. | |||
TMPY-06814 |
Complement C5 Protein, Human, Recombinant (Flag)
C5a,CPAMD4,ECLZB,C5b,C5D,Compleme... |
Human | HEK293 Cells |
Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 187.36 kDa and the accession number is NP_001726.2. | |||
TMPH-03107 |
Complement C5a Protein, Pig, Recombinant (His)
Complement C5a anaphylatoxin,C5 |
Sus scrofa (Pig) | P. pastoris (Yeast) |
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.... | |||
TMPY-06137 |
Complement C5 Protein, Cynomolgus, Recombinant (His)
complement component 5 |
Cynomolgus | HEK293 Cells |
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 188.1 kDa and the accession number is XP_005580972.1. | |||
TMPY-06538 |
Complement C5 Protein, Cynomolgus, Recombinant
complement component 5 |
Cynomolgus | HEK293 Cells |
Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 8.41 kDa and the accession number is XP_005580972.1. | |||
TMPK-01268 |
Complement C2 Protein, Cynomolgus, Recombinant (His)
C2,CO2,Complement C2,C3/C5 convertase,ARMD14 |
Cynomolgus | HEK293 Cells |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC. | |||
TMPH-02607 |
Complement factor B Protein, Mouse, Recombinant (His)
C3/C5 convertase,Complement factor B,Cfb,Bf,H2-Bf |
Mouse | E. coli |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. | |||
TMPY-04902 |
Complement C5a Protein, Mouse, Recombinant
complement component 5 |
Mouse | E. coli |
Complement C5a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. | |||
TMPH-02121 |
SLC5A5 Protein, Human, Recombinant (B2M & His)
|
Human | E. coli |
May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli. SLC5A5 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 27.1 kDa and the accession number is O95436. | |||
TMPY-03872 |
CLEC5A Protein, Rat, Recombinant (His)
C-type lectin domain family 5, member A |
Rat | HEK293 Cells |
CLEC5A Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.6 kDa and the accession number is F7GAV1. | |||
TMPY-05459 |
Complement C5a Protein, Mouse, Recombinant, Biotinylated
complement component 5 |
Mouse | E. coli |
Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. | |||
TMPY-06601 |
GPRC5D Protein, Human, Recombinant, Biotinylated
GPRC5D |
Human | HEK293 Cells |
GPRC5D Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1. | |||
TMPH-02119 |
SLC5A2 Protein, Human, Recombinant (His & Myc)
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Human | E. coli |
Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.; Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. | |||
TMPY-06806 |
GPRC5D Protein-VLP, Human, Recombinant (GFP)
GPRC5D |
Human | HEK293 Cells |
GPRC5D Protein, Human, Recombinant, Fluorescent is expressed in HEK293 mammalian cells. The predicted molecular weight is 65.81 kDa and the accession number is Q9NZD1. | |||
TMPY-03928 |
CLEC5A Protein, Rhesus, Recombinant (mFc)
C-type lectin domain family 5, member A |
Rhesus | HEK293 Cells |
CLEC5A Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45.3 kDa and the accession number is A0A1D5QX52. | |||
TMPH-03074 |
UBC5A Protein, Japonica rice, Recombinant (His & Myc)
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Rice | E. coli |
E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins. UBC5A Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.6 kDa and the accession number is Q8S920. | |||
TMPH-02532 |
BIRC5 Protein, Mouse, Recombinant (E. coli, His)
Apoptosis inhibitor 4,Apoptosis inhibitor survivin,Baculovir... |
Mouse | E. coli |
BIRC5 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.3 kDa and the accession number is O70201. | |||
TMPK-01193 |
GPRC5D Protein-VLP, Mouse, Recombinant
MGC129713,orphan G-protein coupled receptor,GPRC5D,... |
Mouse | HEK293 Cells |
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Mouse, R... | |||
TMPK-01205 |
MDL-1/CLEC5A Protein, Human, Recombinant (hFc)
DAP12-associating lectin 1,MDL-1,MDL1,CLEC5A,CLECSF... |
Human | HEK293 Cells |
MDL-1/CLEC5A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q9NY25-1. | |||
TMPH-02120 |
SLC5A5 Protein, Human, Recombinant (His)
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Human | E. coli |
Mediates iodide uptake in the thyroid gland. SLC5A5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession number is Q92911. | |||
TMPK-00528 |
GPRC5D Protein-VLP, Cynomolgus, Recombinant
MGC129713,GPRC5D,MGC129714,orphan G-protein coupled... |
Cynomolgus | HEK293 Cells |
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Cynomolg... | |||
TMPH-02533 |
BIRC5 Protein, Mouse, Recombinant (His)
BIRC5,Baculoviral IAP repeat-containing protein 5,A... |
Mouse | P. pastoris (Yeast) |
BIRC5 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is O70201. | |||
TMPY-00507 |
UNC5B Protein, Human, Recombinant (hFc)
unc-5 homolog B (C. elegans),UNC5H2,p53RDL1 |
Human | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular ... | |||
TMPH-02196 |
TXNDC5 Protein, Human, Recombinant (GST)
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Human | E. coli |
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 63.2 kDa and the accession number is Q8NBS9. | |||
TMPY-04133 |
UNC5B Protein, Human, Recombinant (His)
UNC5H2,p53RDL1,unc-5 homolog B (C. elegans) |
Human | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular ... | |||
TMPK-01218 |
MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc)
MDL1,DAP12-associating lectin 1,MDL-1,CLEC5A,CLECSF... |
Mouse | HEK293 Cells |
MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is Q9R007-1. | |||
TMPY-06494 |
GPRC5D Protein-VLP, Human, Recombinant
GPRC5D |
Human | HEK293 Cells |
GPRC5D Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1. | |||
TMPY-06718 |
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent
GPRC5D |
Human | HEK293 Cells |
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 32.83 kDa and the accession number is Q9NZD1. | |||
TMPY-06807 |
GPRC5D Protein-VLP, Mouse, Recombinant (Flag)
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Mouse | HEK293 Cells |
GPRC5D Protein, Mouse, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 35.8 kDa and the accession number is Q9JIL6-2. | |||
TMPY-00648 |
UNC5A Protein, Human, Recombinant (hFc)
UNC5H1,unc-5 homolog A (C. elegans) |
Human | HEK293 Cells |
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,... | |||
TMPH-01709 |
Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc)
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Human | E. coli |
Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is Q9HC84. | |||
TMPH-02032 |
GPRC5A Protein, Human, Recombinant (GST)
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Human | E. coli |
Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling. May act as a lung tumor suppressor. GPRC5A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.0 kDa and the accession number i... | |||
TMPH-02315 |
XRCC5 Protein, Human, Recombinant (His & Myc)
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Human | E. coli |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind... | |||
TMPH-02197 |
TXNDC5 Protein, Human, Recombinant
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Human | E. coli |
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 36.2 kDa and the accession number is Q8NBS9. | |||
TMPY-03760 |
CLEC5A Protein, Rhesus, Recombinant (His)
C-type lectin domain family 5, member A |
Rhesus | HEK293 Cells |
CLEC5A Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is A0A1D5QX52. | |||
TMPH-01022 |
C5AR1 Protein-VLP, Human, Recombinant (His)
C5a anaphylatoxin chemotactic receptor 1,CD88,C... |
Human | HEK293 Cells |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-... | |||
TMPH-02314 |
XRCC5 Protein, Human, Recombinant (His & MBP)
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Human | Baculovirus Insect Cells |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind... | |||
TMPH-01023 |
C5AR1 Protein, Human, Recombinant (Cell-Free, His)
C5a anaphylatoxin chemotactic receptor 1,C5 |
Human | E. coli |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression syst... | |||
TMPY-00999 |
UNC5A Protein, Human, Recombinant (His)
unc-5 homolog A (C. elegans),UNC5H1 |
Human | HEK293 Cells |
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,... | |||
TMPY-04003 |
UNC5B Protein, Rat, Recombinant (hFc)
unc-5 homolog B (C. elegans) |
Rat | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular we... | |||
TMPH-00992 |
BIRC5 Protein, Human, Recombinant (His & SUMO)
API4,Apoptosis inhibitor survivin,BIRC5,IAP4,Baculo... |
Human | E. coli |
BIRC5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPJ-01363 |
CLIC5 Protein, Human, Recombinant (His)
Chloride Intracellular Channel Protein 5,CLIC5 |
Human | E. coli |
Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 can insert into membranes and form selective ion channels regulated by actin that may transport chloride ions. It may play a role in the regulation of transepithelial ion absorption and secretion. CLIC5 specif... | |||
TMPY-06719 |
GPRC5D Protein, Human, Recombinant (His & FLAG)
GPRC5D |
Human | HEK293 Cells |
GPRC5D Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 32.83 kDa and the accession number is Q9NZD1. | |||
TMPH-03038 |
Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)
Cobra venom factor,Complement C3 homolog,CVFk,CVF |
Naja kaouthia | E. coli |
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re... | |||
TMPH-02973 |
VDB Protein, Mouse, Recombinant (His)
|
Mouse | P. pastoris (Yeast) |
Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. VDB Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 53.9 kDa and the accession number is P21614. | |||
TMPH-02845 |
Properdin Protein, Mouse, Recombinant (His & Myc)
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Mouse | HEK293 Cells |
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). | |||
TMPH-02844 |
Properdin Protein, Mouse, Recombinant (His)
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Mouse | E. coli |
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). | |||
TMPH-02972 |
VDB Protein, Mouse, Recombinant (E. coli, His)
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Mouse | E. coli |
Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. VDB Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 57.4 kDa and the accession number is P21614. | |||
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