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Search Results for " angiotensin-converting enzyme "

131

抑制剂 & 化合物

21

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Cat. No.	Product Name	Target	Signaling Pathways
T76169	Angiotensin-converting enzyme
	Angiotensin-converting enzyme (ACE)血管紧张素转换酶是一种二羧基肽酶，它将非活性的血管紧张素 I (Ang I) 转化为活性的 Ang II，并降解活性的缓激肽 (BK)。Angiotensin-converting enzyme 是一种有效的血管收缩剂，常用于生化研究。
T7510	Leucylarginylproline	RAAS	Endocrinology/Hormones
	Leucylarginylproline 是一种血管紧张素转换酶抑制剂，IC50=为0.27μM。
T1484	Perindoprilat Perindoprilate,培哚普利	RAAS; MRP; AChR	Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
	Perindoprilat (Perindoprilate) 是一种血管紧张素转换酶抑制剂。
T1489	Fosinopril sodium SQ28555,福辛普利钠	RAAS	Endocrinology/Hormones
	Fosinopril sodium 是一种血管紧张素转换酶（ACE）抑制剂的前药，能够作用于高血压和慢性心力衰竭。
T13865	Resorcinolnaphthalein	RAAS	Endocrinology/Hormones
	Resorcinolnaphthalein 是一种特异性的血管紧张素转换酶 2 激活剂，EC50=19.5 μM。Resorcinolnaphthalein 能够用于高血压和肾纤维化的研究
T1145	Diminazene Aceturate	Others; Serine Protease; Parasite	Microbiology/Virology; Others; Proteases/Proteasome
	Diminazene aceturate 是血管紧张素转化酶 2 的激活剂，具有强效抗炎特性。它还是一种抗锥虫药物，适用于牲畜。它主要生化机理是通过与富含腺嘌呤-胸腺嘧啶碱基对的位点发生特异性相互作用，以非插入方式与锥虫动子体 DNA 结合。
T16116	MLN-4760	RAAS	Endocrinology/Hormones
	MLN-4760 是选择性的人ACE2抑制剂，IC50=0.44 nM，对人ACE2的选择性是其他相关蛋白的 5000 多倍，包括人睾丸 ACE (IC50，>100 μM) 和牛 carboxypeptidase A (IC50，27 μM)。
T7714	Temocapil	Tyrosinase	Proteases/Proteasome
	Temocapil 是一种酪氨酸激酶抑制剂。
TP1828	N-Acetyl-Ser-Asp-Lys-Pro	RAAS	Endocrinology/Hormones
	N-Acetyl-Ser-Asp-Lys-Pro 通过酶促处理胸腺素 β4 在骨髓细胞中形成。它抑制多能造血干细胞进入细胞周期的 S 期，并防止小鼠中的 Ara-C 致死性。
T7686	Ramiprilat	RAAS	Endocrinology/Hormones
	Ramiprilat 是 Ramipril 的活性代谢物，是一种口服有活力的血管紧张素转换酶 (ACE) 抑制剂，其 Ki=7 pM。它可用于研究心力衰竭以及高血压。
T7339	Angiotensin (1-7) Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO	RAAS; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性，因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮，是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大，并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。
T1605	Enalapril MK-421,依那普利	RAAS; MRP	Endocrinology/Hormones; Immunology/Inflammation
	Enalapril 是一种血管紧张素转换酶（ACE）抑制剂。
T7808	Alacepril Cetapril,阿拉普利,DU-1219	RAAS	Endocrinology/Hormones
	Alacepril (DU-1219) 是一种具有口服活性血管紧张素转换酶 (ACE) 抑制剂，具有长效抗高血压作用。
T6340	Enalaprilat Dihydrate 依那普利拉二水合物,MK-422,MK-422 Dihydrate	RAAS; Autophagy	Autophagy; Endocrinology/Hormones
	Enalaprilat Dihydrate (MK-422 Dihydrate) 是一种有效的血管紧张素转化酶抑制剂，IC50为 1.94 nM。
T6698	Temocapril hydrochloride CS-622 HCl,Acecol,Temocapril HCl,CS-622,盐酸替莫普利	RAAS	Endocrinology/Hormones
	Temocapril hydrochloride (CS-622 HCl) 是血管紧张素转化酶 (ACE) 抑制剂。Temocapril HCl 能够用于充血性心力衰竭、急性心肌梗死、高血压、胰岛素抵抗和肾脏疾病的研究。
T1645	Ramipril HOE-498,Tritace,雷米普利,Altace,Carasel	Apoptosis; RAAS	Apoptosis; Endocrinology/Hormones
	Ramipril (Altace) 是一种ACE 抑制剂，IC50为5 nM。
T5030	Zofenopril calcium SQ26991,佐芬普利钙,Zofenopril (calcium)	RAAS; Reactive Oxygen Species	Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Zofenopril calcium (SQ26991) 是一种抗氧化剂和血管紧张素转化酶 (ACE) 抑制剂。
T0180	Benazepril hydrochloride 盐酸贝那普利,CGS 14824A HCl,Benazepril HCl,CGS14824A	RAAS	Endocrinology/Hormones
	Benazepril hydrochloride (CGS 14824A HCl) 是一种血管紧张素转化酶（ACE）抑制剂，能够作用于高血压。
T2679	BMS-265246 BMS265246	CDK	Cell Cycle/Checkpoint
	BMS-265246 是一种有效的选择性 CDK1/2 抑制剂，对 CDK1/cyclin B 和 CDK2/cyclin E 的 IC50分别为6 nM 和9 nM。
T6542	Imidapril hydrochloride Novaloc,Imidapril HCl,盐酸咪达普利,Tanapril,TA-6366	RAAS	Endocrinology/Hormones
	Imidapril hydrochloride (Tanapril) 是一种血管紧张素转换酶 (ACE) 抑制剂，具有抗高血压活性。
T0706	Lisinopril dihydrate Lisinopril,Renacor,赖诺普利二水合物,MK-521 (dihydrate)	RAAS; MRP	Endocrinology/Hormones; Immunology/Inflammation
	Lisinopril dihydrate （MK-521) 是一种血管紧张素转化酶抑制剂。Lisinopri dihydrate 能够作用于高血压，充血性心力衰竭和心脏病等。
T5329	Trandolapril	Angiotensin-converting Enzyme (ACE)	Metabolism
	Trandolapril 是 Trandolaprilat 的前体药物。Trandolapril 是一种口服血管紧张素转换酶抑制剂，在高血压和充血性心力衰竭及心肌梗死领域有研究价值。
T0805	Quinapril hydrochloride CI-906,PD-109452-2,盐酸喹那普利,Quinapril HCl	RAAS	Endocrinology/Hormones
	Quinapril hydrochloride (PD-109452-2) 是一种血管紧张素转化酶(ACE) 抑制剂的原药。
T3281	Delapril hydrochloride indalapril,地拉普利盐酸盐,Alindapril Hydrochloride,Delapril Hydrochloride,盐酸地拉普利,CV 3317	RAAS	Endocrinology/Hormones
	Delapril hydrochloride (indalapril) 是一种血管紧张素转化酶抑制剂，能够用于心血管疾病的研究。
T1484L	Perindopril erbumine 培哚普利叔丁胺,培哚普利叔丁胺盐,S9490-3,Perindopril tert-butylamine salt	Apoptosis; RAAS; MRP	Apoptosis; Endocrinology/Hormones; Immunology/Inflammation
	Perindopril erbumine (S9490-3) 是一种长效血管紧张素转换酶抑制剂。
T1462	Captopril SQ 14225,甲巯丙脯酸,卡托普利,SQ-14534,SA333	RAAS	Endocrinology/Hormones
	Captopril (SA333) 是一种含巯基的，具有口服活性的血管紧张素转换酶(ACE)抑制剂，IC50=0.025 μM，广泛应用于高血压和充血性心力衰竭的研究。Captopril 也是NDM-1抑制剂，IC50=7.9 μM。
T6595	Moexipril hydrochloride 莫昔普利盐酸盐,Moexipril HCl,RS-10085,SPM 925,CI-925	Apoptosis; RAAS	Apoptosis; Endocrinology/Hormones
	Moexipril hydrochloride (Moexipril HCl) 是一种有口服活性的，不含巯基的血管紧张素转化酶抑制剂，可治疗高血压和充血性心力衰竭。
T6486	Enalapril Maleate MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate,马来酸依那普利	RAAS	Endocrinology/Hormones
	Enalapril Maleate (MK-421 Maleate) 一种是血管紧张素转化酶（ACE）抑制剂。
T6444	Cilazapril Monohydrate Ro 31-2848 monohydrate,Justor,西拉普利,西拉普利水合物	RAAS	Endocrinology/Hormones
	Cilazapril Monohydrate (Justor) 是一种血管紧张素转化酶抑制剂，能够作用于高血压和充血性心力衰竭的研究。
T25832	Moveltipril Moveltipril calcium,MC-838,Altiopril calcium	RAAS	Endocrinology/Hormones
	Moveltipril (Moveltipril calcium) 是一种强效血管紧张素转换酶(ACE)抑制剂。
T27827	Libenzapril CGS 16617,Abutapril	Angiotensin-converting Enzyme (ACE)	Metabolism
	Libenzapril (CGS 16617)是一种有效的血管紧张素转换酶抑制剂，可用于研究心肌损伤。
T24588	Palatrigine BW-A 256C,BW A256C	Adrenergic Receptor; Angiotensin-converting Enzyme (ACE)	GPCR/G Protein; Metabolism; Neuroscience
	Palatrigine (BW-A 256C) 是一种具有血管紧张素转换酶抑制和β肾上腺素受体阻断特性的化合物。
T68171L	Zabicipril HCl Zabicipril HCl(83059-56-7 Free base）,S 9650,S 10211	Angiotensin-converting Enzyme (ACE)	Metabolism
	Zabicipril HCl（S 9650）是一种有效的血管紧张素转换酶抑制剂。
T10671	Candoxatril UK 79300	Neprilysin	Metabolism
	Candoxatril (UK 79300) 是具有口服活性的中性肽链内切酶 (NEP，EC 3.4.24.11) 抑制剂，可改善接受血管紧张素转换酶抑制的慢性心力衰竭患者的运动能力。
T27357	FPL-62129 FPL 62129,FPL62129	RAAS; Calcium Channel	Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism
	FPL-62129 是一种钙通道拮抗剂，也是一种新型血管紧张素转换酶抑制剂，具有血管扩张活性，可用于研究心血管疾病。
T25226	Ceronapril Ceronaprilum,SQ 29852,SQ-29852,SQ29852	RAAS	Endocrinology/Hormones
	Ceronapril (SQ 29852) 是一种具有口服活性和高效性的血管紧张素转换酶 (ACE) 抑制剂(IC50 : 36 nM),可用于研究痴呆和高血压。
T20689	Temocaprilat RNH-5139,RS-5139,RNH 5139,RNH5139,替莫普利,RS5139,RS 5139	Angiotensin-converting Enzyme (ACE)	Metabolism
	Temocaprilat (RS5139) 是一种血管紧张素转换酶 (ACE) 抑制剂。 Temocaprilat 通过缺乏 EHBR 的 cMOAT 有效地从胆汁中排泄，而许多其他 ACE 抑制剂对 cMOAT 的亲和力较低。
T68171	Zabicipril	RAAS	Endocrinology/Hormones
	Zabicipril 是一种新型可口服的血管紧张转换酶抑制剂，是一种前药，在体内脱酯后具有抗高血压活性。
TP1750L	H-Ile-Pro-Pro-OH acetate H-Ile-Pro-Pro-OH acetate(26001-32-1 free base)	Angiotensin-converting Enzyme (ACE)	Metabolism
	H-Ile-Pro-Pro-OH acetate 是一种血管紧张素转换酶抑制剂,为乳源三肽。
T24906L	Tuna AI acetate	Angiotensin-converting Enzyme (ACE)	Metabolism
	Tuna AI acetate 是一种源自金枪鱼肌肉的非竞争性血管紧张素转换酶 (ACE) 抑制剂。
T9109	SSAA09E2	RAAS; SARS-CoV	Endocrinology/Hormones; Microbiology/Virology
	SSAA09E2 是一种新型的SARS-CoV 复制抑制剂，通过阻断SARS-S 与SARS-CoV 受体血管紧张素转换酶-2 的早期相互作用发挥作用。
TP1682L	Abz-FR-K(Dnp)-P-OH acetate Abz-FR-K(Dnp)-P-OH acetate (500799-61-1 free base)	Others	Others
	Abz-FR-K(Dnp)-P-OH acetate(500799-61-1 free base) 是一种出色的血管紧张素 I 转换酶 (ACE) 底物，Km 值为 4.0 μM，kcat 值为 210s-1。
T7354	H-Val-Pro-Pro-OH	RAAS	Endocrinology/Hormones
	H-Val-Pro-Pro-OH 是一种血管紧张素 I 转化酶(ACE)的抑制剂(IC50:9 μM)。他是一种来源于牛奶的脯氨酸肽衍生物。
TP1295	Angiotensin I (human, mouse, rat) Angiotensin 1 Human,血管紧张素 1 (人)	Others	Others
	Angiotensin I (human, mouse, rat) 是血管紧张素Ⅱ的前体物质，在血管紧张素转化酶 (ACE) 的参与下裂解成血管紧张素Ⅱ。
TP1920L1	Acein acetate	RAAS	Endocrinology/Hormones
	Acein acetate 是高亲和力血管紧张素转换酶 (ACE) 配体 (Kd = 2.79 nM)。浓度高达 500 nM 时对 ACE 酶活性没有显着影响。增强 NMDA + D-丝氨酸诱导的多巴胺从体外纹状体切片和体内纹状体的释放。
TP1404L	Hemorphin-7 acetate(152685-85-3 free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Hemorphin-7 acetate(152685-85-3 free base) 是一种 hemorphin 肽，一种源自血红蛋白 β 链的内源性阿片肽。 Hemorphin 肽具有镇痛和抗高血压活性，可激活阿片受体并抑制血管紧张素转换酶 (ACE)。
T21049	Quinaprilat CI-928,CI928,CI 928
	Quinaprilat inhibits angiotensin converting enzyme.
T25515	I5B2 I5 B2,I5-B2
	I5B2 is a novel phosphorus-containing angiotensin I converting enzyme inhibitor. Angiotensin I converting enzyme is produced by Actinomadura sp.
T28581	Ro 31-2201 Ro 312201,Ro-31-2201
	Ro 31-2201 is a potent inhibitor of angiotensin converting enzyme.
T27608	Indolapril hydrochloride REV 6000A(SS),CI-907,CI 907,CI907,Indolapril HCl
	Indolapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity.

化合物

Angiotensin-converting enzyme

Cat.No: T76169

Leucylarginylproline

Cat.No: T7510

Target: RAAS

Cat.No: T1484

Synonym: Perindoprilate,培哚普利

Target: RAAS, MRP, AChR

Fosinopril sodium

Cat.No: T1489

Synonym: SQ28555,福辛普利钠

Target: RAAS

Resorcinolnaphthalein

Cat.No: T13865

Target: RAAS

Diminazene Aceturate

Cat.No: T1145

Target: Others, Serine Protease, Parasite

Cat.No: T16116

Target: RAAS

Cat.No: T7714

Target: Tyrosinase

N-Acetyl-Ser-Asp-Lys-Pro

Cat.No: TP1828

Target: RAAS

Cat.No: T7686

Target: RAAS

Angiotensin (1-7)

Cat.No: T7339

Synonym: Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO

Target: RAAS, Endogenous Metabolite

Cat.No: T1605

Synonym: MK-421,依那普利

Target: RAAS, MRP

Cat.No: T7808

Synonym: Cetapril,阿拉普利,DU-1219

Target: RAAS

Enalaprilat Dihydrate

Cat.No: T6340

Synonym: 依那普利拉二水合物,MK-422,MK-422 Dihydrate

Target: RAAS, Autophagy

Temocapril hydrochloride

Cat.No: T6698

Synonym: CS-622 HCl,Acecol,Temocapril HCl,CS-622,盐酸替莫普利

Target: RAAS

Cat.No: T1645

Synonym: HOE-498,Tritace,雷米普利,Altace,Carasel

Target: Apoptosis, RAAS

Zofenopril calcium

Cat.No: T5030

Synonym: SQ26991,佐芬普利钙,Zofenopril (calcium)

Target: RAAS, Reactive Oxygen Species

Benazepril hydrochloride

Cat.No: T0180

Synonym: 盐酸贝那普利,CGS 14824A HCl,Benazepril HCl,CGS14824A

Target: RAAS

Cat.No: T2679

Synonym: BMS265246

Target: CDK

Imidapril hydrochloride

Cat.No: T6542

Synonym: Novaloc,Imidapril HCl,盐酸咪达普利,Tanapril,TA-6366

Target: RAAS

Lisinopril dihydrate

Cat.No: T0706

Synonym: Lisinopril,Renacor,赖诺普利二水合物,MK-521 (dihydrate)

Target: RAAS, MRP

Cat.No: T5329

Target: Angiotensin-converting Enzyme (ACE)

Quinapril hydrochloride

Cat.No: T0805

Synonym: CI-906,PD-109452-2,盐酸喹那普利,Quinapril HCl

Target: RAAS

Delapril hydrochloride

Cat.No: T3281

Synonym: indalapril,地拉普利盐酸盐,Alindapril Hydrochloride,Delapril Hydrochloride,盐酸地拉普利,CV 3317

Target: RAAS

Perindopril erbumine

Cat.No: T1484L

Synonym: 培哚普利叔丁胺,培哚普利叔丁胺盐,S9490-3,Perindopril tert-butylamine salt

Target: Apoptosis, RAAS, MRP

Cat.No: T1462

Synonym: SQ 14225,甲巯丙脯酸,卡托普利,SQ-14534,SA333

Target: RAAS

Moexipril hydrochloride

Cat.No: T6595

Synonym: 莫昔普利盐酸盐,Moexipril HCl,RS-10085,SPM 925,CI-925

Target: Apoptosis, RAAS

Enalapril Maleate

Cat.No: T6486

Synonym: MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate,马来酸依那普利

Target: RAAS

Cilazapril Monohydrate

Cat.No: T6444

Synonym: Ro 31-2848 monohydrate,Justor,西拉普利,西拉普利水合物

Target: RAAS

Cat.No: T25832

Synonym: Moveltipril calcium,MC-838,Altiopril calcium

Target: RAAS

Cat.No: T27827

Synonym: CGS 16617,Abutapril

Target: Angiotensin-converting Enzyme (ACE)

Cat.No: T24588

Synonym: BW-A 256C,BW A256C

Target: Adrenergic Receptor, Angiotensin-converting Enzyme (ACE)

Cat.No: T68171L

Synonym: Zabicipril HCl(83059-56-7 Free base）,S 9650,S 10211

Target: Angiotensin-converting Enzyme (ACE)

Cat.No: T10671

Synonym: UK 79300

Target: Neprilysin

Cat.No: T27357

Synonym: FPL 62129,FPL62129

Target: RAAS, Calcium Channel

Cat.No: T25226

Synonym: Ceronaprilum,SQ 29852,SQ-29852,SQ29852

Target: RAAS

Cat.No: T20689

Synonym: RNH-5139,RS-5139,RNH 5139,RNH5139,替莫普利,RS5139,RS 5139

Target: Angiotensin-converting Enzyme (ACE)

Cat.No: T68171

Target: RAAS

H-Ile-Pro-Pro-OH acetate

Cat.No: TP1750L

Synonym: H-Ile-Pro-Pro-OH acetate(26001-32-1 free base)

Target: Angiotensin-converting Enzyme (ACE)

Tuna AI acetate

Cat.No: T24906L

Target: Angiotensin-converting Enzyme (ACE)

Cat.No: T9109

Target: RAAS, SARS-CoV

Abz-FR-K(Dnp)-P-OH acetate

Cat.No: TP1682L

Synonym: Abz-FR-K(Dnp)-P-OH acetate (500799-61-1 free base)

Target: Others

H-Val-Pro-Pro-OH

Cat.No: T7354

Target: RAAS

Angiotensin I (human, mouse, rat)

Cat.No: TP1295

Synonym: Angiotensin 1 Human,血管紧张素 1 (人)

Target: Others

Cat.No: TP1920L1

Target: RAAS

Hemorphin-7 acetate(152685-85-3 free base)

Cat.No: TP1404L

Target: Opioid Receptor

Cat.No: T21049

Synonym: CI-928,CI928,CI 928

Cat.No: T25515

Synonym: I5 B2,I5-B2

Cat.No: T28581

Synonym: Ro 312201,Ro-31-2201

Indolapril hydrochloride

Cat.No: T27608

Synonym: REV 6000A(SS),CI-907,CI 907,CI907,Indolapril HCl

Cat. No.	Product Name	Target	Signaling Pathways
T5S0106	Peimisine 贝母辛,Ebeiensine	RAAS; AChR	Endocrinology/Hormones; Neuroscience
	Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体，抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放，促进一氧化氮释放，可舒张气管平滑肌，有平喘作用。
T13299	Vicenin 3 维采宁-3,维采宁 3	RAAS	Endocrinology/Hormones
	Vicenin 3来源于广金钱草的地上部分。Vicenin 3是血管紧张素转换酶抑制剂，IC50=46.91 μM。
T8270	Deserpidine 地舍平,Harmonyl	RAAS	Endocrinology/Hormones
	Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂，可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。
T5796	Plantainoside D Isoplantamajoside,车前草苷D	RAAS; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones
	Plantainoside D (Isoplantamajoside) 可以抑制 ACE ，IC50=2.17 mM。Plantainoside D 也是IKK-β抑制剂。
T21418	Lisinopril Linopril,赖诺普利,Zestril,Prinivil,Lisipril	RAAS	Endocrinology/Hormones
	Lisinopril (Prinivil) 是一种血管紧张素转化酶抑制剂，能够作用于高血压，充血性心力衰竭和心脏病等。
T3851	Vicenin 2 Vicenin -2,维采宁 2,新西兰牡荆苷	RAAS	Endocrinology/Hormones
	Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂，IC50=43.83 μM。
T3753	Sinapinic Acid Sinapic acid,芥子酸,Synapoic acid	Apoptosis; RAAS; Reactive Oxygen Species; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。
T6627	Phosphoramidon Disodium Phosphoramidon Disodium Salt,磷酰胺二钠	RAAS; Neprilysin; Others	Endocrinology/Hormones; Metabolism; Others
	Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ，中性肽内切酶 (NEP) 和血管紧张素转换酶 (ACE) 的IC50分别为 3.5 ，0.034 和 78 μM。
TN2295	Vicenin-1 Vicenin -1	Antioxidant; Angiotensin-converting Enzyme (ACE)	Metabolism; oxidation-reduction
	Vicenin-1 (Vicenin -1) 是一种来自豆科植物胡卢巴种子中分离出来的类黄酮糖苷，具有强大的抗炎和抗氧化活性，抑制血管紧张素转换酶 (ACE) 。
T38649	Lyciumin A
	Lyciumin A, a cyclic octapeptide, possesses inhibitory properties against proteases, renin, and angiotensin-converting enzyme. It holds potential for hypertension research.
T38481	Camellianin B
	Camellianin B, a flavonoid compound and metabolite of Camellianin A, exhibits antioxidant properties and acts as an angiotensin converting enzyme (ACE) inhibitor.
TN4103	Ganoderic acid K
	Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities.
TN2045	Pelargonidin-3-O-glucoside chloride	Others; Estrogen/progestogen Receptor	Endocrinology/Hormones; Others
	Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflammatory, anti-estrogenic, and angiotensin-converting enzyme inhibitory activities.
T19911	Rescinnamine Anaprel,Apoterin S,Apoterin
	Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug.
TN5645	Isomartynoside
	Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity.
TN1060	Ganoderol A 灵芝醇 A,灵芝醇A	Others	Others
	Ganoderol A has significant anti-inflammatory activity and protection against UVA damage. it has an inhibitory effect on angiotensin converting enzyme activity and cholesterol biosynthesis.
TN2487	1,3,5,6-Tetrahydroxyxanthone	Others	Others
	1,3,5,6-Tetrahydroxyxanthone shows moderate hepatoprotective activity with EC(50) values of 160.2 +/- 0.6 microM against tacrine-induced cytotoxicity in HepG2 cells. It can inhibit angiotensin-I-converting-enzyme activity in a dose-dependent manner.
TN4860	Pueroside B	COX; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience
	Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A receptor (HMGR), cyclooxygenase-2 (COX2
TN4431	Leucosceptoside A	RAAS; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones
	Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows angiotensin converting enzyme (ACE)
TN1061	Ganoderol B	Androgen Receptor	Endocrinology/Hormones
	Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate cancer and benign prostatic hyperplasia (BPH) therapy through suppressing the function of andr
T79958	Isocrenatoside	Angiotensin-converting Enzyme (ACE)	Metabolism
	Isocrenatoside (compound 6)为环状八肽，具有ACE抑制活性。该化合物可通过乙醇提取Microtoena prainiana茎部分离纯化。研究显示，1 mg/mL浓度下，Isocrenatoside的ACE抑制效率高达99.3%。

天然产物

Cat.No: T5S0106

Synonym: 贝母辛,Ebeiensine

Target: RAAS, AChR

Cat.No: T13299

Synonym: 维采宁-3,维采宁 3

Target: RAAS

Cat.No: T8270

Synonym: 地舍平,Harmonyl

Target: RAAS

Plantainoside D

Cat.No: T5796

Synonym: Isoplantamajoside,车前草苷D

Target: RAAS, PKC

Cat.No: T21418

Synonym: Linopril,赖诺普利,Zestril,Prinivil,Lisipril

Target: RAAS

Cat.No: T3851

Synonym: Vicenin -2,维采宁 2,新西兰牡荆苷

Target: RAAS

Cat.No: T3753

Synonym: Sinapic acid,芥子酸,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Phosphoramidon Disodium

Cat.No: T6627

Synonym: Phosphoramidon Disodium Salt,磷酰胺二钠

Target: RAAS, Neprilysin, Others

Cat.No: TN2295

Synonym: Vicenin -1

Target: Antioxidant, Angiotensin-converting Enzyme (ACE)

Cat.No: T38649

Cat.No: T38481

Ganoderic acid K

Cat.No: TN4103

Pelargonidin-3-O-glucoside chloride

Cat.No: TN2045

Target: Others, Estrogen/progestogen Receptor

Cat.No: T19911

Synonym: Anaprel,Apoterin S,Apoterin

Cat.No: TN5645

Cat.No: TN1060

Synonym: 灵芝醇 A,灵芝醇A

Target: Others

1,3,5,6-Tetrahydroxyxanthone

Cat.No: TN2487

Target: Others

Cat.No: TN4860

Target: COX, PPAR

Leucosceptoside A

Cat.No: TN4431

Target: RAAS, PKC

Cat.No: TN1061

Target: Androgen Receptor

Cat.No: T79958

Target: Angiotensin-converting Enzyme (ACE)

Cat. No.	Product Name	Target	Signaling Pathways
T11193	Enalaprilat-d5 sodium MK-422 D5 Sodium Salt,依那普利拉钠 D5,Enalaprilat D5 Sodium Salt	Others	Others
	Enalaprilat D5 Sodium Salt is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
T11192	Enalapril D5 maleate MK-421 D5 maleate,马来酸依那普利D5	Others	Others
	Enalapril D5 maleate is deuterium labeled Enalapril, which is an angiotensin converting enzyme (ACE) inhibitor.
T11194	Enalaprilat D5 MK-422 D5,依那普利拉 D5	Others	Others
	Enalaprilat D5 is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
T13196	Trandolaprilate D5 Trandolaprilat D5,RU 44403 D5	Others	Others
	Trandolaprilate D5 is a deuterium-labeled Trandolaprilate. Trandolaprilate is an inhibitor of angiotensin-converting enzyme (ACE).
T13195	Trandolapril D5 RU44570 D5	Others	Others
	Trandolapril D5 is a deuterium labeled Trandolapril. Trandolapril is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF).
T71065	Quinapril-d5
	Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con...
T71205	Fosinopril-d7 sodium salt
	Fosinopril-d7 is intended for use as an internal standard for the quantification of fosinopril by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme inhibitor fosinoprilat. Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 µmol/kg, respectively. Fosinopril reduces fractional shortening and decreases left ventricular size in a porcine model of congesti...
T70883	Moexipril-d5
	Moexipril-d5 intended for use as an internal standard for the quantification of moexipril by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 µM for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 µM for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day) ...

同位素

Enalaprilat-d5 sodium

Cat.No: T11193

Synonym: MK-422 D5 Sodium Salt,依那普利拉钠 D5,Enalaprilat D5 Sodium Salt

Target: Others

Enalapril D5 maleate

Cat.No: T11192

Synonym: MK-421 D5 maleate,马来酸依那普利D5

Target: Others

Cat.No: T11194

Synonym: MK-422 D5,依那普利拉 D5

Target: Others

Trandolaprilate D5

Cat.No: T13196

Synonym: Trandolaprilat D5,RU 44403 D5

Target: Others

Trandolapril D5

Cat.No: T13195

Synonym: RU44570 D5

Target: Others

Cat.No: T71065

Fosinopril-d7 sodium salt

Cat.No: T71205

Cat.No: T70883

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