97
27
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T30103 |
APP-CHMINACA
PX-3,PX3 |
||
APP-CHMINACA is a synthetic cannabinoid (CB) featuring a 1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (CHMINACA) base. It displays a 10-fold greater affinity for the central CB1 receptor than that of JWH 018. | |||
T21890 |
JLK6
|
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
JLK-6 是一种γ分泌酶抑制剂,选择性作用于 HEK293细胞的淀粉样β前体蛋白(APP)的γ-分泌酶裂解 APP,抑制 Aβ的生成,但对不 Notch 受体的裂解无影响。 | |||
T9713 |
δ-secretase inhibitor 11
|
Beta Amyloid; Caspase | Apoptosis; Neuroscience; Proteases/Proteasome |
δ-secretase inhibitor 11是一种分泌酶抑制剂,可用作 阿尔茨海默病(AD) 治疗转化开发的先导化合物。 | |||
TP1798 |
Pep-1 (uncapped)
Pep-1 uncapped |
Others | Others |
Pep-1 (uncapped) 是一种能够透过细胞的多肽。 | |||
T38570 |
DMAPP triammonium
Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt |
Others | Others |
DMAPP triammonium (Dimethylallyl diphosphate triammonium) 是一种异戊二烯类化合物的前提物质之一,参与甲羟戊酸 (MVA) 途径,可用于研究与代谢相关的疾病。 | |||
T78337 |
Mouse IgG2a kappa, Isotype Control
|
||
Mouse IgG2a kappa, Isotype Control 是鼠源IIgG2a kappa 抗体的同型抗体。 | |||
T126471 | 3'-Deoxy-4-O-methylepisappanol | ||
3'-Deoxy-4-O-methylepisappanol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126471。 | |||
T78612 | APPA | Apoptosis | Apoptosis |
APPA为一种醛糖还原酶抑制剂,能够抑制大鼠多元醇途径,有效预防细胞凋亡及链脲佐菌素引发的糖尿病症状,显示出对糖尿病肾病(DN)研究的应用潜力。 | |||
T75859 |
FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
|
||
FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS 是Exendin-4多肽衍生物。 | |||
TP1519 |
Amylin (IAPP), feline
|
||
Amylin (IAPP), feline is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas. | |||
T78244 |
Human IgG4 kappa, Isotype Control
|
||
HumanIgG4kappa Isotype Control为人源化单克隆抗体,用作human IgG4κ抗体的同型对照。 | |||
T81756 |
Mouse IgG3 kappa, Isotype Control
|
||
MouseIgG3kappa, Isotype Control为鼠源单克隆抗体,充当mouse IgG3κ抗体的同型对照。 | |||
T82161 |
Human IgG1 (D265A) kappa, Isotype Control
|
||
HumanIgG1(D265A) kappa, Isotype Control是一种人鼠嵌合型抗体,用作HumanIgG1(D265A)κ抗体的同型对照。 | |||
T126481 |
Sappanone B
|
||
Sappanone B 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126481。 | |||
T126391 |
Sappanol
|
||
Sappanol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126391。 | |||
T81758 |
Mouse IgG2b kappa, Isotype Control
|
||
MouseIgG2bkappa Isotype Control是mouse IgG2bκ抗体的同型对照,属于鼠源单克隆抗体。 | |||
T78341 |
Human IgG1 (F405L) kappa, Isotype Control
|
||
HumanIgG1(F405L) kappa, Isotype Control为人-鼠嵌合型单克隆抗体,作为HumanIgG1(F405L)κ抗体的同型对照使用。 | |||
T78340 |
Human IgG1 (N297A) kappa, Isotype Control
|
||
HumanIgG1(N297A) kappa, Isotype Control为具有人-鼠嵌合结构的抗体,作为HumanIgG1(N297A)κ 抗体的同型对照物。 | |||
T81757 |
Mouse IgG2c kappa, Isotype Control
|
||
MouseIgG2ckappa, Isotype Control为mouse IgG2cκ同型对照的鼠源单克隆抗体。 | |||
T81317 |
Rabbit IgG1 kappa, Isotype Control
|
||
RabbitIgG1kappa, Isotype Control为兔源IgG1κ同型对照单克隆抗体,用于科研中作为Rabbit IgG1κ抗体的实验对照。 | |||
T66146 |
(SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-Palladium
|
||
(SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-Palladium 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66146,CAS号为 1028206-56-5。 | |||
T28818 | SMAPP1 | ||
SMAPP1 is an activator of protein phosphatase 1 (PP1). SMAPP1 induces PP1 activity in vitro and activates latent HIV-1 provirus in cultured and primary T cells. | |||
T82160 |
Human IgG1 (D270N) kappa, Isotype Control
|
||
HumanIgG1(D270N) kappa, Isotype Control为人-鼠嵌合型抗体, 作为HumanIgG1(D270N)κ 抗体的同型对照品。 | |||
T82158 |
Human IgG1 (S239D/I332E) kappa, Isotype Control
|
||
HumanIgG1(S239D/I332E) kappa, Isotype Control为一种人源-鼠源嵌合型单克隆抗体,作为HumanIgG1(S239D/I332E)κ抗体之同型对照物。 | |||
T82156 |
Human IgG3 kappa, Isotype Control
|
||
HumanIgG3kappa, Isotype Control为人-鼠嵌合型抗体,作为human IgG3κ抗体同型对照使用。 | |||
T78242 |
Human IgG1 kappa, Isotype Control
|
||
HumanIgG1kappa, Isotype Control为人源化单克隆抗体,作为human IgG1κ抗体的同型对照物。 | |||
T22856 |
IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]
|
Others | Others |
IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral | |||
T2806L |
Lappaconitine HCl
Lappaconitine hydrochloride |
||
Lappaconitine HCl is a centrally acting non-opioid analgesic and class-I antiarrhythmic. It acts by binding to the site-2 receptor and irreversibly blocking hH1 sodium channels. | |||
T36760 | KQMEEEAVRLFIEWLKNGGPSSGAPPPS | ||
KQMEEEAVRLFIEWLKNGGPSSGAPPPS is a Exendin-4 peptide derivative. Exendin-4 is a pure GLP-1 receptor agonist. Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may relates to dual GLP-1/glucagon receptor agonists. Their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as for reduction of excess food intake. These dual GLP-1/glucagon receptor agonists show reduced activity on the GIP receptor to reduce ... | |||
T76028 |
Amylin (IAPP), feline TFA
|
||
Amylin (IAPP), feline TFA,一种来自猫科动物、含37个氨基酸的多肽,为胰岛β细胞的主要分泌物之一。作为调节肽,它能够抑制胰岛素和胰高血糖素的分泌。 | |||
T13663 |
Ds-HAPP
|
Others | Others |
Ds-HAPP is an anthrancenyl and dansyl fluorophore ligand. | |||
T78339 |
Human IgG4 (S228P) kappa, Isotype Control
|
||
HumanIgG4(S228P) kappa, Isotype Control为人-鼠嵌合型单克隆抗体,作为humanIgG4(S228P)κ抗体的同型对照使用。 | |||
T82159 |
Human IgG1 (K214R) kappa, Isotype Control
|
||
HumanIgG1(K214R) kappa, Isotype Control为HumanIgG1(K214R)κ 抗体的人源化同型对照,属于人-鼠嵌合型抗体。 | |||
T78336 |
Mouse IgG1 kappa, Isotype Control
|
||
MouseIgG1kappa Isotype Control 为 mouse IgG1κ 抗体的同型对照鼠源单克隆抗体。 | |||
T81760 |
Mouse IgG1 (D265A) kappa, Isotype Control
|
||
MouseIgG1(D265A) kappa, Isotype Control 为鼠源IgG1 κ类同型对照单克隆抗体,适用作为mouse IgG1(D265A)κ抗体的实验对照。 | |||
T38039 |
(E)-C-HDMAPP (ammonium salt)
|
||
Synthetic and natural alkyl phosphates, also known as phosphoantigens, stimulate the proliferation of γδ-T lymphocytes. Isopentenyl pyrophosphate, and related derivatives including (E)-hydroxy-dimethyl-allyl pyrophosphate ((E)-HDMAPP), are particularly effective activators of γδ-T cells. (E)-C-HDMAPP is the pyrophosphonate form of (E)-HDMAPP. The pyrophosphonate moiety in (E)-C-HDMAPP is much less susceptible to chemical or enzymatic hydrolysis than its pyrophosphate counterpart. As a result, (E... | |||
T126375 |
4-O-Methylepisappanol
|
||
4-O-Methylepisappanol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126375。 | |||
T125353 | Apparicine | ||
Apparicine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125353。 | |||
T69053 | ANAPP3 | ||
ANAPP3 is a P2x-purinoceptor antagonist. It affects contractions in various muscle groups and tissues. | |||
T78243 | Human IgG2 kappa, Isotype Control | ||
HumanIgG2kappa, Isotype Control为人源化单克隆抗体,作为human IgG2κ抗体的标准同型对照使用。 | |||
T73416 | BiCAPPA | ||
BiCAPPA 是一个二价抗朊病毒配体。BiCAPPA 可以减少痒病感染细胞中传染性构象形式的朊病毒蛋白 (PrPSc),EC50值为 0.32 μM。 | |||
T75860 |
GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
|
||
GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS 是 Exendin-4多肽衍生物。 | |||
T78338 |
Rat IgG1 kappa, Isotype Control
|
||
RatIgG1kappa(Isotype Control)是Rat IgG1κ抗体同型对照的鼠源性单克隆抗体。 | |||
T81759 |
Mouse IgG1 (N297A) kappa, Isotype Control
|
||
MouseIgG1(N297A) kappa,Isotype Control 为特定mouse IgG1(N297A)κ 抗体之同型对照,属鼠源单克隆抗体。 | |||
T81755 |
Mouse lgG2a (D265A) kappa, Isotype Control
|
||
Mouse lgG2a (D265A) kappa, Isotype Control 为 mouse lgG2a (D265A) 的鼠源单克隆同型对照抗体。 | |||
T22069 |
D-NMAPPD
|
||
D-NMAPPD ((1R,2R)-B13) 是一种酸性神经酰胺酶 (acid ceramidase) 抑制剂。D-NMAPPD 通过增强神经酰胺的内源性产生来调节 NMDA 受体特性。D-NMAPPD 具有肠癌治疗的潜力。 | |||
T37056 |
D-erythro-MAPP
|
||
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 μM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner. | |||
T125730 |
Glucocapparin
|
||
Glucocapparin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125730。 | |||
T7490 |
ARN2966
|
Beta Amyloid | Neuroscience |
ARN2966 是高效的,针对 APP 表达的转录后调节剂,能够抑制 APP 的表达从而使 Aβ的量降低。 | |||
T28441 |
PPI-1019
PPI1019,Apan |
Beta Amyloid | Neuroscience |
PPI-1019 是一种 APP( β -淀粉状蛋白 A4 )抑制剂,可用于治疗神经系统疾病和研究阿尔茨海默病(AD)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13589 |
Caesappanin C
|
Others | Others |
Caesappanin C 是一种联苯二聚体,提取自印度尼西亚 Caesalpinia sappan L. 的心材中,具有刺激骨形成和再生的潜力。它在体外显示出对原代成骨细胞的强增殖刺激活性。 | |||
T32570 |
Lappaconine
20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine |
Others | Others |
Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) 衍生自去甲二萜生物碱。 | |||
TJS1779 |
Protosappanin A
原苏木素A,PTA |
NADPH-oxidase; IL Receptor; IκB/IKK; TNF; NF-κB; TLR; ROS; COX; HIV Protease; JAK; NO Synthase; STAT | Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome; Stem Cells |
Protosappanin A (PTA) 是从苏木中分离得到的免疫抑制成分和主要联苯化合物,通过下调 JAK2和 STAT3的磷酸化,抑制 JAK2/STAT3依赖的炎症通路。 | |||
T2806 |
Lappaconitine
高乌甲素,(+)-Lappaconitine |
P2X Receptor; Sodium Channel | Membrane transporter/Ion channel; Neuroscience |
Lappaconitine ((+)-Lappaconitine) 是从高乌头中分离得到的一种天然产物,可用于缓解疼痛的研究。 | |||
TMA1570 |
Sappanone A
|
NF-κB; Nrf2 | Immunology/Inflammation; NF-κB |
Sappanone A 是一种高异黄烷酮,通过调节 Nrf2 和 NF-κB 表现出抗炎作用。Sappanone A 可以减轻卵清蛋白引起的哮喘中的过敏性气道炎症。 | |||
T6S1780 |
Protosappanin B
原苏木素B,Q-100961,FT-0689654 |
Apoptosis | Apoptosis |
Protosappanin B (Q-100961) 是从苏木中提取的一种多酚类天然产物,具有抗肿瘤作用。它通过激活 MDM2 依赖性泛素化过程诱导 p53 蛋白降解。它显著提高细胞活力,抑制细胞凋亡并上调生长相关蛋白 43 的表达。 | |||
T6560 |
Lappaconitine hydrobromide
氢溴酸高乌甲素,Lappaconite HBr,Allapinine |
Others | Others |
Lappaconitine hydrobromide (Allapinine) 是天然生物碱类化合物,具有抗心律失常作用。 | |||
T82338 |
Ganoapplanoid F
|
||
Ganoapplanoid F,一种三萜类化合物,源自Ganoderma applanatum,具有抑制脂肪细胞脂质积累的功能,适用于肥胖研究领域。 | |||
TN4410 | Lappaol C | P-gp; JNK | MAPK; Membrane transporter/Ion channel; Neuroscience |
Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant an | |||
TN6463 |
Lappaol B
|
||
Lappaol B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6463,CAS号为 62359-60-8。 | |||
TN1245 |
3-Deoxysappanchalcone
|
Others; Akt; mTOR | Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling |
3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level. | |||
TN3063 |
4-O-Methylsappanol
|
Antifection | Microbiology/Virology |
4-O-Methylsappanol shows activity against this fungus against Beauveria bassiana. | |||
TN2923 | 3'-Deoxy-4-O-methylsappanol | Tyrosinase | Proteases/Proteasome |
3'-Deoxy-4-O-methylsappanol shows moderate cytotoxicities against cultured human melanoma HMV-II cells with the IC50 value of 872.0 uM ± 2.4. | |||
TN6461 | Isolappaol A | ||
Isolappaol A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6461,CAS号为 131400-96-9。 | |||
T40454 |
DMAPP
Dimethylallyl diphosphate |
||
DMAPP, also known as Dimethylallyl pyrophosphate, is an isoprenoid precursor found in all life forms. It serves as an isomer of isopentenyl pyrophosphate (IPP). | |||
TMA2576 |
Episappanol
|
IL Receptor; TNF | Apoptosis; Immunology/Inflammation |
Episappanol has anti-inflammatory activity , it can significantly inhibit the secretion of the pro-inflammatory cytokines interleukin (IL-6) and tumor necrosis factor-alpha (TNF-α). | |||
TN2180 |
Sappanchalcone
苏木查耳酮 |
IL Receptor; BCL; TNF | Apoptosis; Immunology/Inflammation |
Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor. | |||
TN5673 |
10-O-Methylprotosappanin B
|
||
10-O-Methylprotosappanin B是一种天然产物,属于豆科云实属,其产品编号为 TN5673,CAS号为 111830-77-4。10-O-Methylprotosappanin B可用作对照参考。 | |||
TN1246 | 3-Deoxysappanone B | Others | Others |
3-Deoxysappanone B has vasorelaxation effects, it can mediate endothelium- independent vasodilator action in rat thoracic aortic rings. | |||
TN5670 | Protosappanin A dimethyl acetal | ||
Protosappanin A dimethyl acetal shows significant xanthine oxidase inhibitory activity in a concentration-dependent manner. | |||
TN1072 |
Lappaol A
|
P-gp; JNK | MAPK; Membrane transporter/Ion channel; Neuroscience |
Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant an | |||
TN6462 |
Isolappaol C
|
||
Isolappaol C 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6462,CAS号为 929905-15-7。 | |||
TN4411 |
Lappaol F
|
CDK; P-gp; JNK | Cell Cycle/Checkpoint; MAPK; Membrane transporter/Ion channel; Neuroscience |
1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. <br/> 2. Lappaol F has potential chemosensitizing activity, it may be candidates for developing novel adju | |||
T14305 |
Apicidin
OSI 2040 |
Apoptosis; HDAC; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair |
Apicidin (OSI 2040) 是组蛋白去乙酰化酶(HDAC)抑制剂,具有抗寄生虫活性和抗增殖活性。Apicidin 通过减少 APP/PS1 小鼠中的 Abeta 负荷来减轻记忆缺陷,抑制细胞生长增殖,诱导细胞凋亡和自噬,可用于研究白血病。 | |||
TN1420 |
Bacopaside I
|
Others | Others |
Bacopaside I 是一种皂苷,分离自 Bacopa monniera 中,具有抗氧化活性和清除自由基的功能,有抗抑郁作用。 | |||
T79994 |
7-Deoxy-trans-dihydronarciclasine
|
||
7-Deoxy-trans-dihydronarciclasine 作为生物碱,担任烟草花叶病毒(TMV)抑制剂(IC50: 1.80 μM),亦具有抗神经炎症作用,能够降低Tg2576小鼠大脑皮质中Aβ与APP水平。 | |||
TN4399 | Kushenol C | SGLT; NF-κB; ROS; BACE; Antifection | GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB |
Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). Kushenol C shows antimicrobial activity against Staphylococcus aureus and Streptococcus mutan |