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Search Results for " 15:1 "

372

抑制剂 & 化合物

655

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1229	β-Amyloid (1-15) Amyloid β-Protein (1-15)	Beta Amyloid	Neuroscience
	β-Amyloid (1-15) (Amyloid β-Protein (1-15)) 是 β-淀粉样蛋白片段，可用于研究阿尔茨海默病。
T11634	IL-15-IN-1	IL Receptor; Interleukin	Immunology/Inflammation
	IL-15-IN-1是一种 IL-15依赖性细胞的选择性抑制剂(IC50:0.8 μM)。
T8794	4-MMPB 15-Lipoxygenase Inhibitor 1	Apoptosis; Others; Lipoxygenase	Apoptosis; Metabolism; Others
	4-MMPB (15-Lipoxygenase Inhibitor 1) 是一种选择性15-脂氧合酶抑制剂，其 IC50值为 18 μM，具有前列腺癌的研究潜力。它对大豆 15-脂氧合酶和人 15-脂氧合酶-1 的 IC50 分别为 19.5 μM 和 19.1 μM。
T38082	Tunicamycin 15:1 Mixture
	Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contain a 15-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 15:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) inStreptomycesand directly impacts the biological activity of each individual tunicamycin variant.1,2,3Purified tunicamycin 15:1 withiso,anteiso, or a mixture ofisoandanteisobranching configurations inhibit bacteria...
T10835L1	Cletoquine hydrochloride Cletoquine hydrochloride( 4298-15-1 Free base)	Influenza Virus; Parasite	Microbiology/Virology
	Cletoquine hydrochloride 是 Hydroxychloroquine 的主要活性代谢产物。Cletoquine hydrochloride 也是一种 Chloroquine 衍生物，具有抗基孔肯雅热病毒 (CHIKV) 的能力。Cletoquine hydrochloride 具有抗疟作用。
T39631	Chst15-IN-1 Chst15-IN-1
	Chst15-IN-1 is a powerful, reversible, covalent inhibitor of the Chst15 enzyme. It effectively suppresses the sulfation levels of chondroitin sulfate-E (CS-E) and other closely related sulfotransferases responsible for glycosaminoglycans (GAGs) synthesis. Acting as a selective sulfotransferase inhibitor, Chst15-IN-1 can attenuate the inhibitory actions of chondroitin sulfate proteoglycans (CSPGs), making it a promising candidate for enhancing neuronal repair.
T36169	15-LOX-1 inhibitor 1
	9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and IFN-γ-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells when used at a concentration of 5 μM.
T36147	13,14-dihydro-15-keto Prostaglandin E1 13,14-dihydro-15-keto Prostaglandin E1
	13,14-dihydro-15-keto Prostaglandin E1 可抑制 ADP 诱导的人离体富血小板血浆中的血小板聚集（IC50=14.8 μg/mL），也是 PGE1 代谢物。
T20494L	Acetyl tetrapeptide-15 Acetate Skinasensyl Acetate,Acetyl tetrapeptide-15 Acetate (928007-64-1 Free base)
	Acetyl tetrapeptide-15 Acetate (Skinasensyl Acetate) 是一种用于敏感皮肤的化妆品中的合成肽，是 endomorphin-2 衍生物，通过内啡肽样通路扩大 μ-阿片受体中的神经元兴奋性阈值范围，可用于研究由皮肤高反应性产生的炎症性和神经性疼痛。
TP2246	Endothelin-1 (1-15), amide, human	Others	Others
	Endothelin-1 is one of the there isoforms of endothelin (identified as ET-1, -2, -3) with varying regions of expression and binding to at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC.
TP2250	Galanin (1-15) (porcine, rat)	Others	Others
	N-terminal galanin fragment used to mediate central cardiovascular effects
T37486	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 μM.
T37487	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
T36209	15-keto Prostaglandin A1 15-keto Prostaglandin A1
	Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations. 15-keto PGA1, given at a concentration of 6 μM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II.
TP1528	Angiotensin I/II (1-5) Angiotensin I/II 1-5	RAAS; Others	Endocrinology/Hormones; Others
	Angiotensin I/II (1-5) 是由血管紧张素 I/II 肽转化而来，有 1-5 个氨基酸组成的多肽。血管紧张素 I 是由肾素对血管紧张素原的作用形成的，血管紧张素 I 可产生血管紧张素 II 。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。
T37485	1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
	1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO).
T37284	1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE
	1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.
T61575	USP15-IN-1	DUB	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
	USP15-IN-1 是一种有效的 USP15 抑制剂（IC50 为 3.76 μM）。USP15-IN-1对非小细胞肺癌和白血病细胞具有高度的抗增殖活性。USP15是 cGAS 的互作蛋白，并且 USP15可以促进 cGAS 识别DNA 激活下游信号通路。
T73164	SOS1-IN-15	Raf	MAPK
	SOS1-IN-15 是一种具有口服活性和高效性的 SOS1 抑制剂，具有潜在的抗肿瘤活性。SOS1-IN-15 可用于研究结肠癌。
T15956	Mal-amido-PEG4-NHS ester N-[15-[(2,5-二氧代-1-吡咯烷基)氧基]-15-氧代-3,6,9,12-四氧杂十五烷-1-基]-2,5-二氢-2,5-二氧代-1H-吡咯-1-丙酰胺	Others; PROTAC Linker	Others; PROTAC
	Mal-amido-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T16313	NH2-PEG4-CH2CH2COOH 1-氨基-3,6,9,12-四氧代十五烷-15-酸	Others	Others
	NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
T15661	Kif15-IN-1	Others	Others
	Kif15-IN-1, a mitotic Kinesin family member 15 (Kif15) inhibitor, is utilized in the study of cellular proliferative diseases.
TP1512	[Ala1,3,11,15]-Endothelin TFA
	[Ala1,3,11,15]-Endothelin (TFA) is a highly selective for endothelin A (ETA) and endothelin B (ETB) receptor.[Ala1,3,11,15]-Endothelin is a selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ET
TP1725	Bradykinin (1-5)
	Bradykinin (1-5) is a major stable metabolite of Bradykinin, formed by the proteolytic action of angiotensin-converting enzyme (ACE).The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. Bradykinin (1-5) m
T72950	15-PGDH-IN-1
	15-PGDH-IN-1 是一种有效的15-PGDH 抑制剂，具有口服活性。15-PGDH-IN-1 对重组人15-PGDH 具有抑制活性，IC50值为 3 nM。15-PGDH-IN-1 可用于组织修复和再生的研究。
T79216	Mcl-1 inhibitor 15
	Mcl-1 inhibitor15 (Compound (Ra)-15)，作为一种高效的Mcl-1抑制剂（Ki: 0.02 nM），主要应用于癌症的研究领域。
T75126	Enpp-1-IN-15
	Enpp-1-IN-15 (Compound 88a) 是一种外核苷酸焦磷酸酶/磷酸二酯酶 1 (Enpp-1) 抑制剂，Ki 值为 0.00586 nM。
T61797	HIV-1 inhibitor-15
	HIV-1 inhibitor-15 (compound 9d) is a potent and broad-spectrum inhibitor targeting HIV-1. It exhibits inhibitory activity against HIV-1 WT, L100I, K103N, Y181C, and E138K with respective EC50 values of 1.7 nM, 4 nM, 2 nM, 6 nM, and 9 nM. In addition to its high efficacy, HIV-1 inhibitor-15 possesses favorable solubility, safety profiles, and oral bioavailability [1].
T60495	PARP10/15-IN-1
	PARP10/15-IN-1 (化合物 8l) 是PARP10和PARP15的有效的双重抑制剂，其IC50值分别为 160 nM 和 370 nM，用于癌症领域的研究。
T17886	cIAP1 Ligand-Linker Conjugates 15 hydrochloride E3 ligase Ligand-Linker Conjugates 34 hydrochloride	Others	Others
	cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1].
T17887	cIAP1 Ligand-Linker Conjugates 15 E3 ligase Ligand-Linker Conjugates 34	Others	Others
	cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1].
T63614	PD-1/PD-L1-IN-15
	PD-1/PD-L1-IN-15 是 PD-1/PD-L1 的有效抑制剂 (IC50: 60.1 nM)，对肿瘤免疫治疗表现出研究潜力。
T62998	COX-2/15-LOX-IN-1
	COX-2/15-LOX-IN-1 (Compound 14) 是一种 COX-2 和 15-脂氧合酶（15-LOX）抑制剂，可作用于 COX-1 (IC50: 10.65 μM)、COX-2 (IC50: 0.075 μM) 和 15-LOX (IC50: 2.98 μM)。COX-2-IN-25 具有抗炎作用。
T34064	Pigment Blue 15 AI3-26192,EINECS 205-685-1,Blue GLA,Blue pigment,Phthalocyanine Blue BN
	Pigment Blue 15, also called by many names (EINECS 205-685-1), is a bright, crystalline, synthetic blue pigment from the group of phthalocyanine dyes. Its brilliant blue is frequently used in paints and dyes. It is highly valued for its superior propertie
T80439	GTx1-15	Sodium Channel	Membrane transporter/Ion channel
	GTx1-15为一种抑制剂胱氨酸结 (ICK) 肽，能有效抑制电压依赖性钙通道 Cav3.1 以及电压依赖性钠通道 Nav1.3 和 Nav1.7。
T60862	RIPK1-IN-15
	RIPK1-IN-15 (Compound 2.5) 是 RIPK1 的有效抑制剂，在神经退行性疾病、自身免疫性疾病和炎症性疾病研究中具有潜力。
T63075	ALOX15-IN-1
	ALOX15-IN-1 (compound 8b) 是一种选择性的、有效的兔和人 ALOX15 亚油酸加氧酶 (linoleate oxygenase) 活性抑制剂，能够作用于 ALOX15 直系同源物亚油酸 (LA) (IC50: 0.04 μM) 和花生四烯酸 (AA) (IC50: 2.06 μM)。
T61944	IDO1-IN-15
	IDO1-IN-15 是有效的IDO1抑制剂，IC50为127 nM。IDO1-IN-15与Epacadostat 在体外对抗 IDO1 酶的效力相当。
T79405	PARP1-IN-15	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	PARP1-IN-15（Compound 6）是一款针对PARP1的抑制剂，能够抑制坦聚合酶(TNKS)并促进DNA双链断裂损伤。该化合物在诱导肿瘤细胞凋亡(apoptosis)方面具有显著作用，且在三阴性乳腺癌(TNBC)细胞及来源于TNBC患者的类器官中显示出抗癌活性，适用于探究BRCA1突变状态下的TNBC研究。
T63046	HPK1-IN-15
	HPK1-IN-15 是一种选择性的、有效的 HPK1 抑制剂。其中从造血祖细胞克隆的造血祖细胞激酶1 (HPK1) 属于 MAP4Ks 家族。HPK1-IN-15 能够用于与 HPK1 活性相关的疾病或病症 (如癌症) 的研究、预防或改善。
T60941	LSD1-IN-15
	LSD1-IN-15 (compound 1b) 是一种有效的 LSD1抑制剂，可抑制 LSD1-CoREST、MAO-A 和 MAO-B，IC50值分别为 0.149、0.028 和 0.327 μM。LSD1-IN-15 显示前列腺癌 LNCaP 细胞中的细胞生长停滞，IC50值为 9.9 μM。
T37990	15-keto Prostaglandin F1α 15-keto Prostaglandin F1α
	15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins.
T63739	PTP1B-IN-15
	PTP1B-IN-15 是有效的、选择性的蛋白酪氨酸磷酸酶 1B (PTP1B) 抑制剂，对II 型糖尿病和肥胖症表现出研究潜力。
TP1587	β-Casomorphin (1-5), amide, bovine
	β-Casomorphin (1-5), amide, bovine is a peptide of bovine β-Casomorphin.
T78697	Keap1-Nrf2-IN-15
	Keap1-Nrf2-IN-15 (Compound 24a) 作为Keap1-Nrf2蛋白-蛋白相互作用抑制剂，其FP试验与TR-FRET试验的IC50值分别为77 nM和2.5 nM，显示出高效的抑制活性。
T74609	GLP-1R agonist 15
	GLP-1R agonist 15 (Compound 101) 是一种GLP-1受体激动剂。
T37257	13,14-dihydro-15-keto Prostaglandin D1 13,14-dihydro-15-keto Prostaglandin D1
	Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2. 13,14-dihydro-15-keto Prostaglandin D1 (13,14-dihydro-15-keto PGD1) is the theoretical metabolite of PGD1 via the 15-hydroxy PG dehydrogenase metabolic pathway. No biological studies for this compound have been repo...
T79158	h15-LOX-2 inhibitor 1	Lipoxygenase	Metabolism
	h15-LOX-2 inhibitor 1（Comp 105）是一种针对人上皮细胞15-lipoxygenase-2 (h15-LOX-2)的抑制剂，表现出0.34 μM的IC50值。
T36148	13,14-dihydro-15-keto Prostaglandin F1α 13,14-dihydro-15-keto Prostaglandin F1α
	13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach. The measurement of 13,14-dihydro-15-keto PGF1α can be used as a marker of the in vivo production of PGF1α.
T75772	[Ala1,3,11,15]-Endothelin (53-63) (TFA)
	[Ala1,3,11,15]-Endothelin (53-63) (TFA) 是一种ETB 激动剂。[Ala1,3,11,15]-Endothelin (53-63) (TFA) 对 ETB 具有选择性，IC50值范围为 0.33 nM 至 0.61 nM。[Ala1,3,11,15]-Endothelin (53-63) (TFA) 可用于血管收缩的研究。

化合物

β-Amyloid (1-15)

Cat.No: TP1229

Synonym: Amyloid β-Protein (1-15)

Target: Beta Amyloid

Cat.No: T11634

Target: IL Receptor, Interleukin

Cat.No: T8794

Synonym: 15-Lipoxygenase Inhibitor 1

Target: Apoptosis, Others, Lipoxygenase

Tunicamycin 15:1 Mixture

Cat.No: T38082

Cletoquine hydrochloride

Cat.No: T10835L1

Synonym: Cletoquine hydrochloride( 4298-15-1 Free base)

Target: Influenza Virus, Parasite

Cat.No: T39631

Synonym: Chst15-IN-1

15-LOX-1 inhibitor 1

Cat.No: T36169

13,14-dihydro-15-keto Prostaglandin E1

Cat.No: T36147

Synonym: 13,14-dihydro-15-keto Prostaglandin E1

Acetyl tetrapeptide-15 Acetate

Cat.No: T20494L

Synonym: Skinasensyl Acetate,Acetyl tetrapeptide-15 Acetate (928007-64-1 Free base)

Endothelin-1 (1-15), amide, human

Cat.No: TP2246

Target: Others

Galanin (1-15) (porcine, rat)

Cat.No: TP2250

Target: Others

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

Cat.No: T37486

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE

Cat.No: T37487

15-keto Prostaglandin A1

Cat.No: T36209

Synonym: 15-keto Prostaglandin A1

Angiotensin I/II (1-5)

Cat.No: TP1528

Synonym: Angiotensin I/II 1-5

Target: RAAS, Others

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC

Cat.No: T37485

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE

Cat.No: T37284

Cat.No: T61575

Target: DUB

Cat.No: T73164

Target: Raf

Mal-amido-PEG4-NHS ester

Cat.No: T15956

Synonym: N-[15-[(2,5-二氧代-1-吡咯烷基)氧基]-15-氧代-3,6,9,12-四氧杂十五烷-1-基]-2,5-二氢-2,5-二氧代-1H-吡咯-1-丙酰胺

Target: Others, PROTAC Linker

NH2-PEG4-CH2CH2COOH

Cat.No: T16313

Synonym: 1-氨基-3,6,9,12-四氧代十五烷-15-酸

Target: Others

Cat.No: T15661

Target: Others

[Ala1,3,11,15]-Endothelin TFA

Cat.No: TP1512

Bradykinin (1-5)

Cat.No: TP1725

Cat.No: T72950

Mcl-1 inhibitor 15

Cat.No: T79216

Cat.No: T75126

HIV-1 inhibitor-15

Cat.No: T61797

Cat.No: T60495

cIAP1 Ligand-Linker Conjugates 15 hydrochloride

Cat.No: T17886

Synonym: E3 ligase Ligand-Linker Conjugates 34 hydrochloride

Target: Others

cIAP1 Ligand-Linker Conjugates 15

Cat.No: T17887

Synonym: E3 ligase Ligand-Linker Conjugates 34

Target: Others

PD-1/PD-L1-IN-15

Cat.No: T63614

COX-2/15-LOX-IN-1

Cat.No: T62998

Pigment Blue 15

Cat.No: T34064

Synonym: AI3-26192,EINECS 205-685-1,Blue GLA,Blue pigment,Phthalocyanine Blue BN

Cat.No: T80439

Target: Sodium Channel

Cat.No: T60862

Cat.No: T63075

Cat.No: T61944

Cat.No: T79405

Target: PARP

Cat.No: T63046

Cat.No: T60941

15-keto Prostaglandin F1α

Cat.No: T37990

Synonym: 15-keto Prostaglandin F1α

Cat.No: T63739

β-Casomorphin (1-5), amide, bovine

Cat.No: TP1587

Keap1-Nrf2-IN-15

Cat.No: T78697

GLP-1R agonist 15

Cat.No: T74609

13,14-dihydro-15-keto Prostaglandin D1

Cat.No: T37257

Synonym: 13,14-dihydro-15-keto Prostaglandin D1

h15-LOX-2 inhibitor 1

Cat.No: T79158

Target: Lipoxygenase

13,14-dihydro-15-keto Prostaglandin F1α

Cat.No: T36148

Synonym: 13,14-dihydro-15-keto Prostaglandin F1α

[Ala1,3,11,15]-Endothelin (53-63) (TFA)

Cat.No: T75772

Cat. No.	Product Name	Target	Signaling Pathways
TN3594	Cardanol (C15:1)	Apoptosis; Others	Apoptosis; Others
	Cardanol (C15:1) 存在于腰果壳液中，可诱导人黑色素瘤细胞线粒体相关的细胞凋亡。
TN2996	4(15),11-Oppositadien-1-ol	Others	Others
	4(15),11-Oppositadien-1-ol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2996，CAS号为 70389-96-7。
TN2997	4(15),5,10(14)-Germacratrien-1-ol	Others	Others
	4(15),5,10(14)-Germacratrien-1-ol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2997，CAS号为 81968-62-9。
T6S2123	Ginkgolic Acid Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),银杏酸C15:1,银杏酸,Ginkgolic acid C15:1	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	Ginkgolic Acid (Romanicardic acid) 是一种天然化合物，在体外实验中抑制SUMOylation，IC50=3.0 μM。
TN6864	Prosaikogenin F (2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol,前柴胡皂苷F	Others	Others
	Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol) 是一种单糖苷，具有溶血和抗癌特性。
T38299	Tunicamycin V
	Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns.References Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns. References
TN6859	Saikogenin F (1S,2S,4S,5R,8R,9R,10S,13S,14R,17S,18R)-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-ene-2,10-diol	Others	Others
	Saikogenin F ((1S,2S,4S,5R,8R,9R,10S,13S,14R,17S,18R)-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-ene-2,10-diol) 是一种具有抗癌活性的天然产物。
T83420	1α, 2α-Diacetoxy-8β-isobutanoyloxy-9α-benzoyloxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran
	1α, 2α-Diacetoxy-8β-isobutanoyloxy-9α-benzoyloxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran（化合物7）是Pseudolarix kaempferi根皮中发现的一种倍半萜类化合物。
T8002	3-Hydroxycoumarin	Lipoxygenase	Metabolism
	3-hydroxycoumarin 是一种 15-LOX-1的有效氧化还原抑制剂，近期被证明能保护海胆生殖细胞免受紫外线 B 的损伤。
T37974	(S)-Coriolic acid 13(S)-HODE	Lipoxygenase; Mitochondrial Metabolism; PPAR	DNA Damage/DNA Repair; Metabolism
	(S)-Coriolic acid (13(S)-HODE) 是一种重要的细胞内信号剂，是亚油酸与植物和哺乳动物脂氧合酶反应生成的，在各种生物系统中参与细胞增殖和分化。(S)-Coriolic acid 在 1 μM 左右时，它能抑制肿瘤细胞与血管内皮的粘附，能下调 IRGpIIb/IIIa 受体的表达。(S)-Coriolic acid 是15-脂氧合酶 (15-LOX) 代谢产物，常作为内源性配体激活 PPARγ。(S)-Coriolic acid 诱导线粒体功能障碍和气道上皮损伤。
T5S1897	Linderalactone	Apoptosis; Others; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells
	Linderalactone 是从乌药中分离出来的一种倍半萜烯内酯，通过调节凋亡相关蛋白的表达和抑制 JAK/STAT 信号通路来抑制癌细胞生长。它以 IC50值为 15 µM 来抑制肺癌 A-549 细胞的增殖。
TMA0692	Diosbulbin G 山药	Others	Others
	Diosbulbin G是一种天然产物，属于薯蓣科薯蓣属，其产品编号为 TMA0692，CAS号为 67567-15-1。Diosbulbin G可用作对照参考。
TN5624	Adenostemmoside A
	Adenostemmoside A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5624，CAS号为 130217-15-1。
TN6158	Isomurrayafoline B
	Isomurrayafoline B 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6158，CAS号为 107903-15-1。
TN3097	5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane	Others	Others
	5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3097，CAS号为 210108-91-1。
T83447	15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid
	15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid (compound 9) 为从Chloranthus spicatus提取的化学化合物。
TN2637	15-Dihydroepioxylubimin	Others	Others
	15-Dihydroepioxylubimin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2637，CAS号为 129214-59-1。
TN5928	γ-Asarone soasarone,γ-细辛醚
	γ-Asarone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5928，CAS号为 5353-15-1。
T83307	5,4'-Dihydroxy-7-methoxy-6-methylflavane
	5,4'-二羟基-7-甲氧基-6-甲基黄烷（化合物15）是一种从Chinese Dragon's Blood中提取的天然产物。
T83442	17(13→14)-Abeo-ent-3S,13S,16-trihydroxystrob-8(15)-ene
	17(13→14)-Abeo-ent-3S,13S,16-trihydroxystrob-8(15)-ene是一款具有抗炎特性的天然倍半萜内酯。
TN5540	5,6-Dihydroxy-3,7,3',4'-tetramethoxyflavone
	5,6-Dihydroxy-3,7,3',4'-tetramethoxyflavone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5540，CAS号为 63296-15-1。
T14003	15-Acetoxyscirpenol	Caspase	Apoptosis; Proteases/Proteasome
	15-Acetoxyscirpenol, a member of the acetoxyscirpenol moiety mycotoxins (ASMs), potently induces apoptosis and inhibits the growth of Jurkat T cells in a dose-dependent manner. This effect is mediated through the activation of caspases independent of caspase-3[1].
T83553	(4S)-10-Nor-calamenen-10-one
	(4S)-10-Nor-calamenen-10-one（Compound 15）促进小胶质细胞通过LPS刺激产生的NO增强。该化合物为桉树倍半萜烯类，可从Alpinia oxyphylla中提取。
TN3954	ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide	Others	Others
	ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3954，CAS号为 59885-89-1。
T82640	Cyclobisdemethoxycurcumin
	Cyclobisdemethoxycurcumin，作为一种抗氧化剂，在DPPH自由基清除试验中示出约250 μM的IC50，在2-DR氧化试验中显示为15-20 μM的IC50。
T16381	Okadaic acid	Others	Others
	Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted from black sponges of the genus Halic
TN3932	ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide	Others	Others
	ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide shows significant cytotoxic activity against ANA-1 and Jurkat cells with IC50 values 7.12 x 10(-3) and 1.79 x 10(-2) microM.
T80350	Maximin 15
	Maximin 15为源自蟾蜍大脑的抗菌肽，具有针对金黄色葡萄球菌、大肠杆菌和枯草芽孢杆菌的活性，其最小抑菌浓度(MIC)值依次为9.4, 18.8, 75 μg/mL。
T36051	Lipoxin A4 脂氧素 A4,LXA4
	Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 in inducing superoxide generation in human neutrophils at 0.1 μM.2 LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.[2],[3],[4] Analytical and biological comparisons of synth...
T75633	(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid
	(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid (compound 15) 为具有抗结核活性的化合物，对结核分枝杆H37Ra的最小抑菌浓度（MIC）为12.5 μg/mL，并展现出对Vero细胞的细胞毒性，其半数抑制浓度（IC50）值为32 μM[1]。
T80343	MCF
	MCF为源自蜂毒的抗菌肽，对E.coli W 160-37、S.aureus 8530及B.subtilis展现出抗菌活性，其最小抑菌浓度(MIC)值分别为E.coli W 160-37为35-45 μg/ml，S.aureus 8530为25-35 μg/ml，及B.subtilis为15-25 μg/ml。
TN3686	Coccinic acid	Others	Others
	Coccinic acid shows inhibitory effects against colorectal carcinoma HCT-15 and oral epithelial cell line KB-3-1.Mixture of coccinic acid and anwuweizonic acid shows significant inhibitory activity against human decidual cells and rat luteal cells in vitro
TN6014	Norcepharadione B 鱼腥草
	Norcepharadione B shows good inhibitory activity against the replication of HSV-1, it also shows antimalarial activity with EC50 values of 7.5mug/ml. Norcepharadione B exhibits significant cytotoxicity against five human tumor cell lines (A-549, SK-OV-3,
T37272	9(S),12(S),13(S)-TriHOME
	9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...
T8242	Sabinene	Others	Others
	Sabinene 是香料添加剂，具有成为下一代飞机燃料成分的成分。
TN1624	Ethyl cinnamate	Calcium Channel; ROS; NO Synthase	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism
	Ethyl cinnamate 是食品香料和化妆品添加剂，也是哺乳动物组织的优良清除剂。
T3S1553	trans-Cinnamaldehyde Cinnamaldehyde,Cinnamic aldehyde,桂皮醛,反式肉桂醛,Cinnamal,Phenylacrolein	COX; Endogenous Metabolite	Immunology/Inflammation; Metabolism; Neuroscience
	trans-Cinnamaldehyde (Phenylacrolein) 是一种能够用于合成反式肉桂醛-β-环糊精复合物，一种能够食用的抗菌涂层，能够延长鲜切水果的保质期。它是一种能够通过烷基异氰化物与乙炔二羧酸二烷基酯的反应来合成高度多官能的呋喃环。
T40607	2,4,6-Trimethylphenol Mesitol	Others	Others
	2,4,6-Trimethylphenol (Mesitol) 是一种与有机物 (3DOM*) 反应的探针化合物，可在水溶液中被单线态氧快速氧化。
T3858	macranthoidin A 灰毡毛忍冬皂苷甲,金银花	Others	Others
	Macranthoidin A 是一种具有口服活性的、提取于金银花中的皂苷。它对四氯化碳，对乙酰氨基酚和镉所致的肝损伤具有保护作用，对耳巴豆油的溶胀具有明显的抑制作用。
T3368	Alpha-Hederin α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C	Apoptosis; Others	Apoptosis; Others
	Alpha-Hederin (Tauroside E) 是存在于黑种草种子中的一种单桥糖三萜皂苷，具有抗肿瘤作用。它可通过激活线粒体依赖性途径抑制胃癌细胞增殖，诱导凋亡，并有活性氧生成和谷胱甘肽减少。
T36448	(E)-Ajoene
	(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml).1(E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively).2It also inhibits human glutathione reductase andT. cruzitrypanoth...
T0775	Coumarin	Factor Xa; Influenza Virus	Metabolism; Microbiology/Virology
	Coumarin 是中国北沙参中的一种主要生物活性成分，具有抗癌、抗炎和抗病毒等活性。它作为几种抗凝剂的前体具有临床价值，尤其是华法林。
T5777	Phaseoloidin	Others	Others
	Phaseoloidin 是来自烟草细毛虫的高纯酸苷，有助于植物抵抗鳞翅目草食动物。它能够抑制Manduca sexta 和Spodoptera littoralis 的幼虫生长。它具有抗补体特性。
TN1027	β-Amyrin β-香树脂醇,beta-Amyrin	Beta Amyloid	Neuroscience
	β-Amyrin (beta-Amyrin) 是一种番茄果实的表面蜡和蒲公英咖啡中的成分，能抑制淀粉样 β 诱导的增强效应损害。它可用于研究 AD。
TN2058	Persicogenin	Anti-infection	Microbiology/Virology
	Persicogenin 是分离自 Rhus retinorrhoea 中，具有抗癌作用。
T3738	3-(4-Hydroxyphenyl)-1-propanol	LTR	Immunology/Inflammation
	3-(4-Hydroxyphenyl)-1-propanol 能够用于合成 (-)-centrolobine。
T2865	Oleanolic Acid Oleanic acid,Caryophyllin,齐墩果酸	HIV Protease; Endogenous Metabolite; Antibiotic; Autophagy	Autophagy; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Oleanolic Acid (Caryophyllin) 是具有抗癌活性的一种天然产物。
TMS2262	(-)-CAMPHOR L-Camphor,左旋樟脑	Others	Others
	(-)-CAMPHOR (L-Camphor) 是樟脑的手性中间体，在食品中用作风味添加剂和甜味剂。
T2825	Cyclopamine 环巴胺,11-Deoxojervine	Hedgehog/Smoothened; Endogenous Metabolite; Smo	GPCR/G Protein; Metabolism; Stem Cells
	Cyclopamine (11-Deoxojervine) 是Hedgehog 通路的拮抗剂，细胞实验中IC50=46 nM。它还是选择性Smo 抑制剂。
TN1463	Calycanthoside Isofraxidin 7-O-beta-D-Glucoside	NO Synthase; Antifection	Immunology/Inflammation; Microbiology/Virology
	Calycanthoside (Isofraxidin 7-O-beta-D-Glucoside) 是一种从当归中分离出来的天然化合物。 Calycanthoside 具有抗炎和抗菌作用。
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天然产物

Cardanol (C15:1)

Cat.No: TN3594

Target: Apoptosis, Others

4(15),11-Oppositadien-1-ol

Cat.No: TN2996

Target: Others

4(15),5,10(14)-Germacratrien-1-ol

Cat.No: TN2997

Target: Others

Cat.No: T6S2123

Synonym: Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),银杏酸C15:1,银杏酸,Ginkgolic acid C15:1

Target: Others, E1/E2/E3 Enzyme

Prosaikogenin F

Cat.No: TN6864

Synonym: (2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol,前柴胡皂苷F

Target: Others

Cat.No: T38299

Cat.No: TN6859

Synonym: (1S,2S,4S,5R,8R,9R,10S,13S,14R,17S,18R)-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-ene-2,10-diol

Target: Others

1α, 2α-Diacetoxy-8β-isobutanoyloxy-9α-benzoyloxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran

Cat.No: T83420

3-Hydroxycoumarin

Cat.No: T8002

Target: Lipoxygenase

(S)-Coriolic acid

Cat.No: T37974

Synonym: 13(S)-HODE

Target: Lipoxygenase, Mitochondrial Metabolism, PPAR

Cat.No: T5S1897

Target: Apoptosis, Others, JAK

Cat.No: TMA0692

Synonym: 山药

Target: Others

Adenostemmoside A

Cat.No: TN5624

Isomurrayafoline B

Cat.No: TN6158

5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane

Cat.No: TN3097

Target: Others

15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid

Cat.No: T83447

15-Dihydroepioxylubimin

Cat.No: TN2637

Target: Others

Cat.No: TN5928

Synonym: soasarone,γ-细辛醚

5,4'-Dihydroxy-7-methoxy-6-methylflavane

Cat.No: T83307

17(13→14)-Abeo-ent-3S*,13S*,16-trihydroxystrob-8(15)-ene

Cat.No: T83442

5,6-Dihydroxy-3,7,3',4'-tetramethoxyflavone

Cat.No: TN5540

15-Acetoxyscirpenol

Cat.No: T14003

Target: Caspase

(4S)-10-Nor-calamenen-10-one

Cat.No: T83553

ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide

Cat.No: TN3954

Target: Others

Cyclobisdemethoxycurcumin

Cat.No: T82640

Cat.No: T16381

Target: Others

ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide

Cat.No: TN3932

Target: Others

Cat.No: T80350

Cat.No: T36051

Synonym: 脂氧素 A4,LXA4

(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid

Cat.No: T75633

Cat.No: T80343

Cat.No: TN3686

Target: Others

Norcepharadione B

Cat.No: TN6014

Synonym: 鱼腥草

9(S),12(S),13(S)-TriHOME

Cat.No: T37272

Cat.No: T8242

Target: Others

Ethyl cinnamate

Cat.No: TN1624

Target: Calcium Channel, ROS, NO Synthase

trans-Cinnamaldehyde

Cat.No: T3S1553

Synonym: Cinnamaldehyde,Cinnamic aldehyde,桂皮醛,反式肉桂醛,Cinnamal,Phenylacrolein

Target: COX, Endogenous Metabolite

2,4,6-Trimethylphenol

Cat.No: T40607

Synonym: Mesitol

Target: Others

macranthoidin A

Cat.No: T3858

Synonym: 灰毡毛忍冬皂苷甲,金银花

Target: Others

Cat.No: T3368

Synonym: α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C

Target: Apoptosis, Others

Cat.No: T36448

Cat.No: T0775

Target: Factor Xa, Influenza Virus

Cat.No: T5777

Target: Others

Cat.No: TN1027

Synonym: β-香树脂醇,beta-Amyrin

Target: Beta Amyloid

Cat.No: TN2058

Target: Anti-infection

3-(4-Hydroxyphenyl)-1-propanol

Cat.No: T3738

Target: LTR

Cat.No: T2865

Synonym: Oleanic acid,Caryophyllin,齐墩果酸

Target: HIV Protease, Endogenous Metabolite, Antibiotic, Autophagy

Cat.No: TMS2262

Synonym: L-Camphor,左旋樟脑

Target: Others

Cat.No: T2825

Synonym: 环巴胺,11-Deoxojervine

Target: Hedgehog/Smoothened, Endogenous Metabolite, Smo

Cat.No: TN1463

Synonym: Isofraxidin 7-O-beta-D-Glucoside

Target: NO Synthase, Antifection

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