64
37
36
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9174 |
Icerguastat
Sephin 1,lcerguastat,IFB-088 |
Phosphatase | Metabolism |
Icerguastat (IFB-088) 是一种缺乏 α2-肾上腺素能活性的 Guanabenz 衍生物,是一种磷酸酶调节亚单位 PPP1R15A (R15A)的选择性抑制剂。它能够抑制 eIF2α 去磷酸化,从而延长保护反应。它具有抗朊病毒作用。 | |||
T28225 |
Obicetrapib
TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995 |
CETP | Metabolism |
Obicetrapib (AMG-899) 是胆固醇酯转移蛋白的抑制剂。 | |||
TP1071 |
Nociceptin
Orphanin FQ,孤菲肽 |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Nociceptin (Orphanin FQ) 是一种 17 个氨基酸的多肽,是 nociceptin 受体的内源性配体,具有缓解疼痛的作用。 | |||
T68127 |
Picenadol
LY-150720,LY150720,LY 150720 |
Others | Others |
Picenadol (LY 150720) 是N-甲基-4-苯基哌啶衍生物的外消旋混合物,具有激动剂 - 拮抗剂阿片性质。Picenadol 具有中枢镇痛活性。 | |||
T23076L |
Nociceptin (1-7) acetate
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Nociceptin (1-7) acetate 是一种有效的阿片受体样受体 1 (ORL1) 受体激动剂。 Nociceptin (1-7) 与 nociceptin 结合可降低痛觉过敏并具有镇痛活性。 | |||
T9499 |
Icenticaftor
QBW251 |
CFTR | Membrane transporter/Ion channel |
Icenticaftor (QBW251) 是一种具有口服活性CFTR 通道增强剂,可用于慢性阻塞性肺疾病 (COPD) 和囊性纤维化研究,对F508del 和G551D CFTR 的EC50分别为 79 和 497 nM。 | |||
TP1885L1 |
[(pF)Phe4]Nociceptin(1-13)NH2 acetate
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
[(pF)Phe4]Nociceptin(1-13)NH2 acetate 是一种选择性 NOP 受体激动剂,pKi 为 10.68,pEC50 为 9.31。 [(pF)Phe4]Nociceptin(1-13)NH2 acetate 对 δ、κ 和 μ 阿片受体具有高选择性(>3000 倍)。 | |||
TP1793L |
Nociceptin (1-13) amide TFA
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Nociceptin (1-13) amide TFA (178064-02-3 free base) 是一种有效的 Opioid receptor-like1 (ORL1) receptor 激动剂,对小鼠输精管的 pEC50 为 7.9,与大鼠前脑膜结合的 Ki 为 0.75 nM。 | |||
T1132 |
Nicergoline
尼麦角林,Nicergolinum,Nimergoline |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Nicergoline (Nicergolinum) 是一种有效的,选择性的、具有口服活性的α1A-肾上腺素能受体拮抗剂,是一种溴烟碱酸的麦角林衍生物。它具有血管舒张作用,可以改善阿尔茨海默症小鼠的认知功能。 | |||
T19861 |
Niceritrol
Perycit,Cardiolipol,戊四烟酯,Bufor |
Others | Others |
Niceritrol (Cardiolipol) 是一种烟酸酯,可降低总血浆以及 VLD 和 LD 脂蛋白部分中的胆固醇和甘油三酯。 | |||
T74990 | ICeD-2 | ||
ICeD-2 是一种细胞死亡诱导剂,可诱导HIV-1感染的细胞死亡。 ICeD-2 介导的HIV-1感染细胞杀伤依赖于HIV-1蛋白酶活性。ICeD-2 可有效阻断二肽基肽酶DPP8和DPP9对 Gly-Pro-AMC 的水解。ICeD-2 显示 PBMC 中 DPP9 的强稳定性。 | |||
T75586 | Dendraspis Angusticeps Venom | ||
Dendraspis Angusticeps Venom(Eastern Green Mamba Venom)是从Dendraspis Angusticeps(绿曼巴蛇)中提取的蛇毒,其含有利钠肽和成束蛋白(抗胆碱酯酶毒素)。这种毒液能够增强乙酰胆碱的释放,并抑制苯甲酸奎宁环与毒蕈碱乙酰胆碱受体(mAChR)的结合。 | |||
T76135 | Hemicellulase | ||
Hemicellulase(半纤维素酶),糖苷水解酶家族成员,广泛应用于生化研究领域。该酶能够分解植物纤维中的葡萄糖及其与水分子的聚合物,是自然界植物生物量及碳流降解的关键酶类。 | |||
T75909 |
[Nphe1]Nociceptin(1-13)NH2 TFA
|
||
[Nphe1]Nociceptin(1-13) NH2 TFA 是一种 Nociceptin/orphanin FQ (NC)内源性配体,是一种选择性和竞争性的 ociceptin receptor 拮抗剂,不具有激动剂活性。[Nphe1]nociceptin(1-13)NH2 选择性结合重组 nociceptin 受体(pKi=8.4),拮抗 nociceptin 对 CHO 细胞中 cAMP 积累的抑制作用(pA2=6.0)。[Nphe1]Nociceptin(1-13)NH2 有可能作为一种止痛试剂。 | |||
T78302 |
Atacicept
TACI-Ig,TACI-Fc 5 |
||
Atacicept (TACI-Ig)是一种重组融合蛋白,结合了TACI受体的细胞外配体结合区和人类IgG的Fc区。该化合物通过与B淋巴细胞刺激因子和增殖诱导配体结合而抑制B细胞的刺激作用,被用于B细胞介导的自身免疫性疾病的研究中。 | |||
T60235 |
(Rac)-Lanicemine
|
||
(Rac)-Lanicemine ((Rac)-AZD6765) 是 Lanicemine 的外消旋体。Lanicemine (AZD6765) 是一种低捕获的NMDA 受体拮抗剂,Ki 为 0.56-2.1 μM;在CHO 和非洲爪蟾卵母细胞中,IC50分别为 4-7 μM 和 6.4 μM。Lanicemine 具有抗抑郁作用。 | |||
T69308 |
Spliceostatin A
|
Apoptosis | Apoptosis |
Spliceostatin A 是 抗癌剂和剪接抑制剂,抑制剪接体剪接机制,抑制有丝分裂克隆扩增和脂肪生成。Spliceostatin A 诱导细胞周期停滞在 G1 和 G2/M 期,诱导细胞凋亡。 | |||
T82023 |
Ivicentamab
GEN-3009 |
||
Ivicentamab (GEN-3009),一种人源化IgG1κ亚型的单克隆抗体,靶向CD37,主要应用于癌症相关研究。 | |||
T80598 |
Davoceticept
CD80 vIgD-Fc,ALPN-202 |
||
Davoceticept (ALPN-202; CD80 vIgD-Fc) 是一种靶向CTLA-4的单克隆抗体。它包含CD80的(1-107)片段,该片段通过肽基连接子与IGHG1 Fc连接。Davoceticept通常在CHO(中国仓鼠卵巢)细胞中表达。 | |||
T60471 |
Lanicemine dihydrochloride
|
||
Lanicemine (AZD6765) dihydrochloride 是NMDA 通道的低捕获拮抗剂,Ki 值为 0.56-2.1 μM,在CHO 和爪蟾卵母细胞的IC50分别为 4-7 μM 和 6.4 μM。Lanicemine (AZD6765) dihydrochloride 具有持续的抗抑郁功效。 | |||
T23076 |
Nociceptin(1-7)
Nociceptin (1-7) |
Others | Others |
Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia | |||
TP1885 |
[(pF)Phe4]Nociceptin(1-13)NH2
|
||
Highly potent and selective nociceptin/orphanin FQ receptor (OP4) agonist peptide (pKi = 10.68; pEC50 = 9.80). Displays > 8000-fold selectivity over δ, κ, and μ opioid receptors and has relatively long lasting pronociceptive, hypotensive, negative inotrop | |||
T15706 |
Lanicemine
AZD6765,拉尼西明 |
Others | Others |
Lanicemine is a low-trapping NMDA channel blocker. It also has a binding (Ki: 0.56-2.1 μM). | |||
T24063 |
Ficellomycin
Antibiotic U 47929,U 47929 |
||
Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria. | |||
T124461 |
Tricetinidin chloride
|
||
Tricetinidin chloride 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124461。 | |||
T32747 |
Licorice saponin C2
Saponin C2, from licorice,Licoricesaponin C2 |
||
Licorice saponin C2 is an oleanane-type triterpene oligoglycoside extracted from the air-dried root of Glycyrrhiza uralensis. | |||
T35014 |
Valdice
|
||
Valdice is a village and municipality in Jičín District in the Hradec Králové Region of the Czech Republic. | |||
T78309 |
Telitacicept
RC18 |
||
Telitacicept (RC18) 是一种全人源TACI-Fc融合蛋白,兼具BLyS和APRIL抑制作用,有效阻断B淋巴细胞增殖,适用于B细胞自身免疫性疾病研究。 | |||
T70309 |
Dicetrorelix pamoate
|
||
Dicetrorelix pamoate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently lutein... | |||
T68504 | Obicetrapib calcium | ||
Obicetrapib calcium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial effect for cardiovascular disease risk reduction. | |||
T63219 | Piceid 6″-O-azelaic acid ester | ||
Piceid 6″-O-azelaic acid ester 表现出较强的细胞内酪氨酸酶抑制作用和脱色活性。 | |||
T126313 |
Piceatannol 4'-O-glucoside
Piceatannol 4'-O-β-D-glucopyranoside |
Antioxidant | oxidation-reduction |
Piceatannol 4'-O-glucoside (Piceatannol 4'-O-β-D-glucopyranoside)是一种天然抗氧化剂,是从大黄提取出来的葡萄糖苷,可用于研究糖尿病。 | |||
T75597 | Loxosceles Spiniceps Venom | ||
Loxosceles Spiniceps Venom 是一种可以从Loxosceles Spiniceps 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物,富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类,包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶,鞘磷脂酶 D 负责坏死的发展。 | |||
T30228 |
Avicenol A
|
||
Avicenol A is a cancer chemopreventive agent. | |||
T73682 |
(R)-Lanicemine
|
||
(R)-Lanicemine ((R)-AZD6765) 是 Lanicemine 的低活性的 R 型异构体。Lanicemine (AZD6765) 是一种低捕获的NMDA 受体拮抗剂,Ki 为 0.56-2.1 μM。CHO 和爪蟾卵母细胞中,IC50分别为 4-7 μM 和 6.4 μM。具有抗抑郁作用。 | |||
T77034 |
Inbakicept
N-803 |
||
Inbakicept (ALT-803) 是一种 IL-15超激动剂,由 IL-15突变体和 IL-15Rα-Fc 融合体组成。Inbakicept 可放大抗 CD20单抗介导的 NK 细胞反应和抗体依赖性细胞毒性 (ADCC)。INbakicept 也增加 NK 细胞的脱粒或 IFNγ 的产生。 | |||
T81675 |
NICE-01
AP1867-PEG2-JQ1,AP-PEG2-JQ1 |
||
NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1)是一款具有双功能的化合物,它通过特异性结合到细胞内特定亚细胞区室中的蛋白质,并以BRD4蛋白的核定位含溴结构域作为诱导,实现将胞浆中的货物输送至细胞核。 | |||
T68505 | Obicetrapib sodium | ||
Obicetrapib sodium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial effect for cardiovascular disease risk reduction. | |||
T124859 | Junicedric acid | ||
Junicedric acid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124859。 | |||
T68503 | Obicetrapib potassium | ||
Obicetrapib potassium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial effect for cardiovascular disease risk reduction. | |||
T15214 |
Emicerfont
GW876008 |
Others | Others |
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM). | |||
T77026 | Goflikicept | ||
Goflikicept (RPH 104) 是一种可选择性结合并灭活循环中的 IL-1ß 和 IL-1α 的杂合蛋白。此化合物在研究ST段抬高型心肌梗死(STEMI)方面具有潜力。 | |||
T75896 |
[Arg14,Lys15]Nociceptin TFA
|
||
[Arg14,Lys15]Nociceptin TFA 是一种高效、选择性的 NOP (ORL1; OP4)受体激动剂,EC50为 1 nM。[Arg14,Lys15]Nociceptin TFA 对阿片受体具有较高的选择性,对 NOP、μ、δ 和 κ 受体的 IC50值分别为 0.32、280、>10000 和 1500 nM。 | |||
T75906 |
Nociceptin (1-13), amide TFA
|
||
Nociceptin (1-13), amide TFA 是一种有效的阿片受体 ORL1 (OP4)受体激动剂,对小鼠输精管 pEC50值为 7.9,与大鼠前脑膜结合的 Ki 值为 0.75 nM。 | |||
T75908 |
Nociceptin(1-7) TFA
|
||
Nociceptin(1-7) 是 Nociceptin 的 N 端生物活性片段。Nociceptin(1-7) 是一种有效的ORL1(NOP)受体激动剂,具有缓解疼痛活性。Nociceptin(1-7) 联合 Nociceptin 可降低体内对痛觉的敏感。 | |||
T32746 |
Licorice acid
Licorice acid zinc |
||
Licorice acid is used for a zinc supplement in nutrition. | |||
T125803 |
cis-Piceid
|
||
cis-Piceid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125803,CAS号为 148766-36-3。 | |||
T28228 |
Okicenone
|
||
Okicenone is an antibiotic, interferring with HuR RNA binding, HuR trafficking, T-cell activation and cytokine expression. | |||
TP1986 |
[Arg14,Lys15]Nociceptin
|
||
Highly potent and selective NOP receptor agonist (EC50 = 1 nM). Displays > 875-fold selectivity over opioid receptors (IC50 values are 0.32, 280, > 10000 and 1500 for NOP, μ, δ and κ receptors respectively). Longer lasting and 30-fold more potent than noc | |||
TP1793 |
Nociceptin (1-13), amide
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Nociceptin (1-13), amide 是一种 ORL1 (OP4) 受体激动剂,与大鼠前脑膜结合的 Ki 为 0.75 nM,对小鼠输精管的 pEC50 为 7.9。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1961 |
Myricetin 3-O-glucoside
Myricetin 3-O-beta-D-glucopyranoside |
Immunology/Inflammation related | Immunology/Inflammation |
Myricetin 3-O-glucoside (Myricetin 3-O-beta-D-glucopyranoside) 是一种从Tibouchina paratropica 提取 的黄酮醇。Myricetin 3-O-glucoside 具有很多活性,包括抗利什曼原虫、抗炎和抗菌活性。 | |||
T3851 |
Vicenin 2
Vicenin -2,维采宁 2,新西兰牡荆苷 |
RAAS | Endocrinology/Hormones |
Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂,IC50=43.83 μM。 | |||
T2998 |
Dihydromyricetin
Ampelopsin,Ampeloptin,二氢杨梅素 |
Influenza Virus; GABA Receptor; DNA/RNA Synthesis; mTOR; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling |
Dihydromyricetin (Ampelopsin) 是一种来自 Ampelopsis Grossedentata 的天然抗氧化剂类黄酮,是二氢嘧啶酶抑制剂,IC50 为 48 μM。它通过抑制mTOR 信号从而激活自噬。它还是流感依赖 RNA 的RNA 聚合酶抑制剂,IC50为 22 μM。 | |||
TN5171 |
Tricetin
|
Apoptosis; Others; Nrf2 | Apoptosis; Immunology/Inflammation; Others |
Tricetin 是一种从石榴中分离出的类黄酮。Tricetin 是 Keap1-Nrf2 蛋白相互作用(PPI)的强效竞争性抑制剂,通过激活 Nrf2/HO-1 信号通路和阻止线粒体依赖性细胞凋亡通路,保护帕金森病患免受 6-OHDA 诱导的神经毒性的影响。Tricetin 通过 Akt/GSK-1β途径抑制鼻咽癌的迁移和指示性蛋白酶早老素-1(PS-1)表达。Tricetin 抑制由Egr-1介导的氧化LDL 诱导的内皮炎症,保护大鼠软骨细胞免受IL-1β诱导的炎症和细胞凋亡。 | |||
TN1962 |
Myricetin 3-O-galactoside
Myricetin 3-O-beta-D-galactopyranoside |
NOS; Xanthine Oxidase | Immunology/Inflammation; Metabolism |
Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) 可抑制黄嘌呤氧化酶 (xanthine oxidase; XO) 活性,脂质过氧化并清除自由基。杨梅素3- o -半乳糖苷具有很多作用包括细胞毒性、抗氧化、抗基因毒性、抗感染性、抗炎作用和抗氧化活性,其主要作用是抑制诱导型一氧化氮合酶(iNOS)的合成。Myricetin 3-O-galactoside 抑制脂质过氧化的 IC50 为 160 μg/mL。 | |||
T3S0401 |
Piceatannol 3'-O-glucoside
白皮杉醇 3'-O-葡萄糖苷,Piceatannol 3-glycoside,Quzhaqigan,曲札茋苷、白皮杉醇-3'-O-葡萄糖苷 |
Arginase; NO Synthase | Immunology/Inflammation |
Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) 是大黄的一种活性成分,通过抑制精氨酸酶活性激活内皮细胞一氧化氮合酶,抑制Arginase I 和Arginase II,IC50值分别为 11.22 和 11.06 μM。它可增加肺血氧分压,减少肺间质水肿,从而保护肺损伤。 | |||
TN1877 |
Lonicerin
忍冬苦苷,金银花 |
Apoptosis; Antibacterial | Apoptosis; Microbiology/Virology |
Lonicerin 是一种抗藻酸盐分泌蛋白的黄酮类化合物,对铜绿假单胞菌有抑制作用。它可预防脂多糖诱导的急性肺损伤的炎症和细胞凋亡。 | |||
TN1866 |
Licoricesaponin G2
甘草皂苷G2 |
||
Licoricesaponin G2 是一种从 Glycyrrhiza aspera 中提取出的五环三萜类化合物,可用于区分粗甘草和蜂蜜加工甘草。 | |||
T13299 |
Vicenin 3
维采宁-3,维采宁 3 |
RAAS | Endocrinology/Hormones |
Vicenin 3来源于广金钱草的地上部分。Vicenin 3是血管紧张素转换酶抑制剂,IC50=46.91 μM。 | |||
TN2289 |
Licorice-saponin H2
18Β,20Α-甘草酸,Licoricesaponin H2 |
Others | Others |
Licorice-saponin H2 (Licoricesaponin H2) 是一种从甘草中获得的皂苷。 | |||
T20225 |
Dicentrine, (-)-
L-Dicentrine,荷包牡丹碱,NSC 251699,NSC251699,NSC-251699 |
Others | Others |
Dicentrine, (-)- (NSC-251699) 是一种在几种植物物种中发现的非卟啉生物碱,在小鼠内脏痛的急性模型中显示出显著的镇痛活性。 | |||
T0579 |
Myricetin
Cannabiscetin,杨梅素 |
Apoptosis; PI3K; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Metabolism; PI3K/Akt/mTOR signaling |
Myricetin (Cannabiscetin) 是一种存在于常见植物中的类黄酮,具有强抗氧化,抗糖尿病,抗癌和抗炎活性。 | |||
TN2295 |
Vicenin-1
Vicenin -1 |
Antioxidant; Angiotensin-converting Enzyme (ACE) | Metabolism; oxidation-reduction |
Vicenin-1 (Vicenin -1) 是一种来自豆科植物胡卢巴种子中分离出来的类黄酮糖苷,具有强大的抗炎和抗氧化活性,抑制血管紧张素转换酶 (ACE) 。 | |||
TN4782 |
Picein
Salinigrin,云杉甙,Salicinerein,Piceoside,Ameliaroside |
Antioxidant; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
Picein (Piceoside) 源自 Picrorhiza kurroa,具有抗氧化特性。 | |||
T0610 |
Piceatannol
白皮杉醇,trans-Piceatannol,Astringenin |
Apoptosis; Serine/threonin kinase; PKA; Syk; PKC; Autophagy | Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors |
Piceatannol (Astringenin) 是一种Syk 抑制剂,可降低由 TNF 诱导的 iNOS 表达,可研究急性肺损伤。它是存在于各种水果和蔬菜中天然存在的多酚二苯乙烯,可诱导细胞自噬和凋亡,具有抗癌和抗炎特性。 | |||
T83395 |
24-Hydroxy-licorice-saponin A3
|
||
24-Hydroxy-licorice-saponin A3为一种来源于G. uralensis的齐墩果烷型三萜皂苷(OTS)。 | |||
TN1577 |
Dicentrine
荷苞牡丹碱,荷包牡丹碱 |
Others | Others |
Dicentrine, a selective α±(1)-adrenoceptor antagonist with potent antiarrhythmic and antihypertensive activities, it also has antinociception in different models of chemical pain. | |||
T11848 |
Licorice glycoside C2
甘草苷 C2 |
Others | Others |
Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. | |||
T80950 |
Tricetin 7-O-glucoside
|
||
Tricetin 7-O-glucoside (compound 33)为一种黄酮类单-O-糖苷。 | |||
TN6232 |
Myricetin 3,7,3'-trimethyl ether 5'-O-glucoside
|
||
Myricetin 3,7,3'-trimethyl ether 5'-O-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6232,CAS号为 2170444-56-9。 | |||
TN4436 |
Licoricesaponin E2
|
Others | Others |
Licoricesaponin E2 displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 umol/L, it could significantly increase the cytotoxic activity after hydrolysis. | |||
T73853 |
Amicetin
|
||
Amicetin,一种强效的抗生素,对革兰氏阳性菌表现出显著的抗生活性,主要通过抑制蛋白质合成机制发挥作用。 | |||
TN1865 |
Licoricesaponin A3
甘草皂苷A3 |
Others | Others |
Licoricesaponin A3 shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μMol/L. | |||
T83134 |
Alterbrassicene B
|
||
Alterbrassicene B,一种从甘蓝链格孢菌(Alternaria brassicicola)分离得到的抗癌化合物。 | |||
TN1559 |
Dehydrodicentrine
|
AChR | Neuroscience |
Dehydrodicentrine showed strong acetylcholinesterase (AChE) inhibitory effects with the IC50 value of 2.98 μM. | |||
TN4605 | Myriceric acid B | HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibits aromatase activity with IC50 val | |||
TN4606 |
Myriceric acid C
|
Endothelin Receptor | GPCR/G Protein |
Myriceric acid C has cytotoxic activity against human lung carcinoma and breast carcinoma. | |||
TN2793 |
2-Picenecarboxylic acid
|
Others | Others |
2-Picenecarboxylic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2793,CAS号为 118172-80-8。 | |||
TN4058 |
Filicenol B
|
Others | Others |
Filicenol B is a natural product from Adiantum lunulatum. | |||
T81731 |
Myricetin-3-O-rutinoside
|
||
Myricetin-3-O-rutinoside(Compound 3)是从Picea abies中分离出的天然化合物。 | |||
T81769 |
Mollicellin I
|
||
Mollicellin I(compound 1)为一种Depsidone类化合物。其对Bre04人乳腺癌细胞系、Lu04人肺癌细胞系以及N04人神经瘤细胞系的生长抑制活性低,GI50s均超过10 μg/mL。 | |||
T81770 |
Mollicellin H
|
||
Mollicellin H, 次级代谢物源于真菌C. brasiliense,显示出免疫调节、细胞毒性和抗肿瘤等多种生物活性。它对三种人类癌细胞系——乳腺癌 (Bre04)、肺癌 (Lu04) 和神经瘤 (N04) 的生长抑制半数有效浓度 (GI50s) 分别为5.1 μg/mL、6.5 μg/mL 和2.5 μg/mL。 | |||
T75608 | Myricetin 3-O-α-L-arabinopyranoside | ||
Myricetin 3-O-α-L-arabinopyranoside 抑制 A2E 光氧化诱导的RPE 细胞死亡。Myricetin 3-O-α-L-arabinopyranoside 对视网膜变性具有保护作用,可保护蓝光 (BL) 诱导对 RPE 细胞和小鼠模型的损伤。 | |||
TN4607 |
Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside
|
Others | Others |
Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4607,CAS号为 142449-93-2。 | |||
TC0037 |
colchiceine
|
||
colchiceine 在生命科学相关研究中具有广泛的应用。 | |||
T82030 |
Isohericerin
|
||
Isohericerin 是一种发现于多种海洋生物中的异吲哚啉酮类化合物,以其具有潜在的生物活性而备受研究关注。 | |||
T19898 |
Methylarbutin
ß-PMP-Glc;4-Methoxyphenyl β-D-Glucopyranoside,ß-PMP-Glc,4-Methoxyphenyl β-D-Glucopyranoside |
Others | Others |
Methylarbutin (ß-PMP-Glc;4-Methoxyphenyl β-D-Glucopyranoside) 是一种冰重结晶抑制剂 (IRI)。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01776 |
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His)
carboxylesterase 2,CES2A1,CE-2,PCE-2,iCE |
Human | HEK293 Cells |
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.4 kDa and the accession number is O00748-1. | |||
TMPH-01315 |
CASR Protein, Human, Recombinant (GST)
CAP4,MCH5,Caspase-8,CASP-8,CASP8,FADD-homologous ICE |
Human | E. coli |
CASR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 93.6 kDa and the accession number is P41180. | |||
TMPY-02831 |
Caspase-7 Protein, Human, Recombinant (His)
ICE-LAP3,LICE2,MCH3,CASP-7,caspase 7, apop... |
Human | E. coli |
Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are two major classes of caspases: initiators and effectors. The initiator isoforms (caspases-1,-4,-5,-8,-9,-10,-11,-12) are activated by, and interact with, upstream adaptor molecules through protein-protein interaction domains known as CARD and DED. Effector caspases (-3,-6,-7) are r... | |||
TMPH-01057 |
Caspase-8 Protein, Human, Recombinant (His)
Caspase-8,CAP4,Apoptotic cysteine protease,FLICE,FA... |
Human | E. coli |
Caspase-8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.9 kDa and the accession number is Q14790. | |||
TMPJ-01256 |
Caspase-10 Protein, Human, Recombinant (His)
CASP10,FAS-Associated Death Domain Protein Interleukin-1B-Co... |
Human | E. coli |
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human ca... | |||
TMPH-01055 |
Caspase-1 Protein, Human, Recombinant (HA)
Interleukin-1 beta convertase,Interleukin-1 beta-converting ... |
Human | E. coli |
Caspase-1 Protein, Human, Recombinant (HA) is expressed in E. coli expression system with C-HA tag. The predicted molecular weight is 11.4 kDa and the accession number is P29466. | |||
TMPH-00441 |
PRDX1 Protein, Cricetulus griseus, Recombinant (His)
|
Chinese hamster | P. pastoris (Yeast) |
PRDX1 Protein, Cricetulus griseus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9JKY1. | |||
TMPK-01192 |
Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His)
Envelope glycoprotein E,ORF68,gE |
Varicella-zoster virus (strain Oka vaccine) | HEK293 Cells |
VZV glycoprotein E (gE) is most abundantly expressed on the surface of infected cells, and is an essential component for virus replication and cell-to-cell transmission. It is also the main target of virus-specific antibodies and T cell responses that is often selected as vaccine candidate antigen. | |||
TMPH-02458 |
PRNP Protein, Mesocricetus auratus, Recombinant (His & Myc)
|
Mesocricetus auratus | E. coli |
PRNP Protein, Mesocricetus auratus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.3 kDa and the accession number is P04273. | |||
TMPH-00442 |
PGK1 Protein, Cricetulus griseus, Recombinant (His)
|
Chinese hamster | P. pastoris (Yeast) |
PGK1 Protein, Cricetulus griseus, Recombinant (His) is expressed in Yeast. | |||
TMPH-00439 |
GAPDH Protein, Cricetulus griseus, Recombinant (His)
|
Chinese hamster | E. coli |
GAPDH Protein, Cricetulus griseus, Recombinant (His) is expressed in E. coli. | |||
TMPH-03074 |
UBC5A Protein, Japonica rice, Recombinant (His & Myc)
|
Rice | E. coli |
E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins. UBC5A Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.6 kDa and the accession number is Q8S920. | |||
TMPH-00437 |
Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO)
Ctsd,Cathepsin D |
Chinese hamster | E. coli |
N/A. Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.3 kDa and the accession number is G3I4W7. | |||
TMPH-03681 |
Varicella-zoster virus (strain Dumas) glycoprotein E/gE Protein (His & SUMO)
|
HHV-3 | E. coli |
Varicella-zoster virus (strain Dumas) glycoprotein E/gE Protein (His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 85.4 kDa and the accession number is P09259. | |||
TMPH-03683 |
Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His)
|
HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His) is expressed in E... | |||
TMPH-00435 |
Beta-Actin Protein, Cricetulus griseus, Recombinant (His)
ACTB,Actin, cytoplasmic 1,Beta-actin |
Chinese hamster | E. coli |
Beta-Actin Protein, Cricetulus griseus, Recombinant (His) is expressed in E. coli. | |||
TMPH-03685 |
Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc)
|
HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The... | |||
TMPH-03682 |
Varicella-zoster virus (strain Dumas) glycoprotein H/gH Protein (His & Myc)
|
HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Varicella-zoster virus (strain Dumas) glycoprotein H/gH Protein (His & Myc) is expressed in E... | |||
TMPH-00440 |
PRDX1 Protein, Cricetulus griseus, Recombinant (E. coli, His)
|
Chinese hamster | E. coli |
PRDX1 Protein, Cricetulus griseus, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPY-06855 |
Varicella-zoster virus (VZV) (strain Oka vaccine) Glycoprotein B/gB Protein
|
VZV | CHO Cells |
Varicella-zoster virus (VZV) is a highly fusogenic virus, but the degree of fusion is dependent on the cell substrate in which the virus is propagated. Varicella-zoster virus (VZV) is classified as an alphaherpesvirus based on its growth characteristics and its ability to become latent in the nervous system of the host. Like all known herpesviruses, VZV encodes a homolog of glycoprotein B (gB). Glycoprotein B (gB) is the most conserved entry glycoprotein among herpesviruses with an amino acid se... | |||
TMPH-00438 |
GLUL Protein, Cricetulus griseus, Recombinant (His)
|
Chinese hamster | E. coli |
GLUL Protein, Cricetulus griseus, Recombinant (His) is expressed in E. coli. | |||
TMPH-01433 |
Hemicentin-1 Protein, Human, Recombinant (His)
|
Human | E. coli |
Hemicentin-1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-03072 |
MPK5 Protein, Japonica rice, Recombinant (His & Myc)
|
Rice | E. coli |
MPK5 Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.0 kDa and the accession number is Q10N20. | |||
TMPH-02457 |
IL-4 Protein, Mesocricetus auratus, Recombinant (His)
|
Mesocricetus auratus | P. pastoris (Yeast) |
IL-4 Protein, Mesocricetus auratus, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is Q60440. | |||
TMPH-03684 |
Varicella-zoster virus (strain Dumas) glycoprotein L/gL Protein (His & Myc)
|
HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. Varicella-zoster virus (strain Dumas) glycoprotein L/gL Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predi... | |||
TMPH-00445 |
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His)
|
Chinese hamster | P. pastoris (Yeast) |
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His) is expressed in Yeast. | |||
TMPH-03073 |
TDX Protein, Japonica rice, Recombinant (His & Myc)
|
Rice | E. coli |
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions and act as chaperone under heat shock. May interact with HSP70 proteins through the TPR repeats. TDX Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 42.0 kDa and the accession number is Q6ES52. | |||
TMPY-06357 |
Varicella-zoster virus (VZV)/HHV-3 Glycoprotein E/gE Protein (His)
|
VZV | HEK293 Cells |
Varicella-zoster virus (VZV)/HHV-3 Glycoprotein E/gE Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.02 kDa and the accession number is Q9J3M8. | |||
TMPH-03742 |
EEF1A1 Protein, Cricetulus griseus, Recombinant (His)
EEF1A,Elongation factor 1-alpha 1,eEF1A-1,EF-1-alpha-1,EF-Tu... |
Chinese hamster | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IFNG promoter-binding complex with TXK and PARP1. | |||
TMPY-06867 |
Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein
|
VZV | CHO Cells |
Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein is expressed in CHO mammalian cells. The predicted molecular weight is 85.17 kDa. | |||
TMPH-02459 |
INGAP Protein, Mesocricetus auratus, Recombinant (His)
|
Mesocricetus auratus | E. coli |
Constituent of ilotropin, which is a partially purified preparation of cellophane wrapping (CW) pancreata. Capable of initiating duct cell proliferation, a prerequisite for islet neogenesis. INGAP Protein, Mesocricetus auratus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.8 kDa and the accession number is Q92778. | |||
TMPH-00436 |
Calreticulin Protein, Cricetulus griseus, Recombinant (His)
ERp60,Calreticulin,Calregulin,CRT,CRP55,HACBP,CALR,Endoplasm... |
Chinese hamster | P. pastoris (Yeast) |
Calreticulin Protein, Cricetulus griseus, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 48.1 kDa and the accession number is Q8K3H7. | |||
TMPH-00444 |
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc)
|
Chinese hamster | E. coli |
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02456 |
IL-12B Protein, Mesocricetus auratus, Recombinant (His & Myc)
|
Mesocricetus auratus | E. coli |
IL-12B Protein, Mesocricetus auratus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.8 kDa and the accession number is Q8CJE6. | |||
TMPH-00443 |
P4HB Protein, Cricetulus griseus, Recombinant (His)
|
Chinese hamster | P. pastoris (Yeast) |
P4HB Protein, Cricetulus griseus, Recombinant (His) is expressed in Yeast. | |||
TMPY-03496 |
EBAG9 Protein, Human, Recombinant (His)
EB9,PDAF,estrogen receptor binding site associated, antigen,... |
Human | E. coli |
RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in s... |