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63

抑制剂 & 化合物

7

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T7635	Raclopride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Raclopride 是多巴胺D2/D3受体拮抗剂，具有抗精神活性，能够结合D2(Ki:1.8 nM)和D3(Ki:3.5 nM)受体。
T7626	Budipine	Others	Others
	Budipine 是抗帕金森病剂的一种。
T9169	MPP+ iodide	Mitochondrial Metabolism; Autophagy	Autophagy; Metabolism
	MPP+ iodide 是一种 5-羟色胺转运体的高亲和力底物，也是一种神经毒素 MPTP 的有毒代谢物，通过选择性破坏黑质多巴胺能神经元，在动物模型中引起帕金森病症状。它被多巴胺转运体吸收进入多巴胺能神经元，通过影响呼吸链复合体 I 对线粒体发挥神经毒性作用。
T8637	DMNB 6-Nitroveratraldehyde,6-硝基藜芦醛	DNA-PK	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	DMNB (6-Nitroveratraldehyde) 可用于合成no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA)。它可用于研究多巴胺能系统的PET。
T0322	Fipexide	Dopamine Receptor; AChR	GPCR/G Protein; Neuroscience
	Fipexide 是对氯苯乙酸衍生物，是哌嗪化学类的精神活性药物，作为促智药物，有用于老年痴呆的研究潜力。它可降低了纹状体腺苷酸环化酶的活性，通过多巴胺能神经传递对认知表现出积极的作用。
T8423	ML417	Dopamine Receptor; Arrestin	GPCR/G Protein; Neuroscience
	ML417 是选择性的，可透过血脑屏障的 D3 多巴胺受体激动剂，EC50=38 nM。它能够促进 D3R 介导的 β-arrestin 易位、G 蛋白介导的信号传导和 pERK 磷酸化，对其他 GPCR 介导的信号传导影响小。它对毒素诱导的多巴胺能神经元变性具有神经保护活性。
T8357	SB-200646	5-HT Receptor	GPCR/G Protein; Neuroscience
	SB-200646 是 5-HT2B/5-HT2C 受体的选择性强效拮抗剂，对5-HT2B、5-HT2C 和 5-HT2A 的pKi 值分别为 7.5、6.9 和 5.2。它有口服活性，在体内具有电生理和抗焦虑特性。
T22026	AGK7	Others; Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	AGK7 是 sirtuin 2 (SIRT2) 抑制剂。它在体外和帕金森病果蝇模型中均能抑制多巴胺能细胞的凋亡。在帕金森病细胞模型中，它改善了 α-突触核蛋白毒性和修饰的包涵体形态
T12256	NS8593 hydrochloride NS8593 HCl	Potassium Channel	Membrane transporter/Ion channel
	NS8593 hydrochloride (NS8593 HCl) 是选择性的 SK 通道抑制剂。它可逆抑制 SK3介导的电流，Kd 值为 77 nM。它抑制所有 SK1-3亚型的 Ca2+依赖性 (在 0.5 μM Ca2+时，Kd 分别为 0.42、0.60 和 0.73 μM)，并且不影响中间电导和大电导的钙激活钾通道。
T0412	Idebenone 艾地苯醌,CV-2619	Apoptosis; Antioxidant; Mitochondrial Metabolism	Apoptosis; Metabolism; oxidation-reduction
	Idebenone (CV-2619) 是一种线粒体保护剂，具有神经保护功效，可用于研究阿尔茨海默病、亨廷顿舞蹈病，可透过血脑屏障，诱导细胞凋亡。
T11277	FG 7142 ZK 39106,LSU-65	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	FG 7142 (LSU-65) 是一种非选择性苯二氮卓类反向激动剂，对含 α1 亚基的 GABAA 受体具有高亲和力，Ki 为 91 nM。它还调节 GABA 诱导的 GABAA 受体上的氯离子通量，表达 α1 亚基，EC50为 137 nM。它可增加酪氨酸羟基化并导致小鼠大脑皮层中 β-肾上腺素受体的上调。
T34616	Seridopidine ACR-343,ACR 343,ACR343	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Seridopidine (ACR343) 是一种多巴胺能活性调节剂，可作为精神分裂症、帕金森病和抽动秽语综合征的口服疗法。
T8653	DOPEXAMINE	Dopamine Receptor	GPCR/G Protein; Neuroscience
	DOPEXAMINE 是一种多巴胺能激动剂。
T1443	Memantine hydrochloride 3,5-二甲基金刚胺盐酸盐,盐酸美金刚,Namenda,Memantine HCl,D-145 (hydrochloride)	P450; GluR; NMDAR; Autophagy; iGluR	Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Memantine hydrochloride (Memantine HCl) 是一种具有一些多巴胺能作用的金刚烷胺衍生物，是一种温和的 NMDA 受体非竞争性拮抗剂，能够抑制 CYP2B6 和 CYP2D6。它可作为抗帕金森剂。
T20993	Memantine	Others	Others
	Memantine 是口服具有活性的、非竞争性的N-甲基-D-天冬氨酸受体拮抗剂，可用于研究中重度阿尔茨海默病。
T13048	SynuClean-D SC-D	Others	Others
	SynuClean-D (SC-D) 是一种 α-突触核蛋白聚集的抑制剂，能够破坏成熟的淀粉样蛋白原纤维，抑制原纤维繁殖，防止帕金森氏病动物模型中多巴胺能神经元的变性。
T4262	BisfluoroModafinil	Dopamine Receptor	GPCR/G Protein; Neuroscience
	BisfluoroModafinil 是一种莫达非的常见替代品，具有增强认知能力的潜力。其中莫达非尼通常用于研究性嗜睡症。
T50054	Opromazine hydrochloride	Others	Others
	Opromazine hydrochloride 属于吩噻嗪类抗精神病药物，通过阻断大脑中的多巴胺受体而降低多巴胺能通路的活性，主要用于治疗精神分裂症和精神病等精神疾病。
TP1310	Neurotensin	Neurotensin Receptor	GPCR/G Protein
	Neurotensin 是一种 13 个氨基酸的神经肽，参与调节促黄体激素和催乳素的释放，并与多巴胺能系统有显着的相互作用。它作为细胞有丝分裂原，作用于各种结肠直肠癌和胰腺癌。
T10674	Potassium Channel Activator 1 钾离子通道激活剂1,ZINC34634569	Potassium Channel	Membrane transporter/Ion channel
	Potassium Channel Activator 1 可用于治疗多巴胺能系统被破坏的疾病或病症的研究，例如情绪障碍 ADHD、精神分裂症和其他精神病状态。
T3106	C-DIM12	Apoptosis; Others	Apoptosis; Others
	C-DIM12是一种人工合成的Nurr1激活剂，可诱导Nurr1和DA 基因表达。
T7549	Talnetant SB 223412	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Talnetant (SB 223412) 是一种选择性、竞争性、脑渗透性 NK3 受体拮抗剂，Ki 为1.4 nM。它比对hNK-2受体的抑制性高100倍，具有调节中脑边缘和中脑皮质多巴胺能神经传递的能力。
T24885L	Tiaspirone hydrochloride BMY-13859 hydrochloride,Tiaspirone hydrochloride（87691-91-6 Free base)	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Tiaspirone hydrochloride (BMY-13859 hydrochloride) 具有抗精神病活性。 Tiaspirone hydrochloride 影响大鼠大脑黑质致密带（A9 DA 细胞）和腹侧被盖区（A10 DA 细胞）多巴胺能神经元的电生理活性。
T33816	Ordopidine ACR-325,ACR 325,ACR325	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Ordopidine (ACR325) 是一种多巴胺能稳定剂，可抑制精神刺激剂引起的多动症，并在不活动时刺激行为。Ordopidine 在体外作为多巴胺 D2 受体拮抗剂起作用，尽管亲和力低，但其依赖于特定状态的行为效应特征是 D2 受体拮抗剂所不具备的。
T2546	Pimozide R6238,匹莫奇特,匹莫齐特	Potassium Channel; Dopamine Receptor; Adrenergic Receptor; STAT	GPCR/G Protein; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Stem Cells
	Pimozide (R6238) 是多巴胺受体拮抗剂，对多巴胺 D1、D2 和 D3 受体的 Ki 值分别为 588、1.4 和 2.5 nM。它也是STAT3和STAT5的抑制剂，对 α1 肾上腺素受体也有较高亲和性，Ki 值为 39 nM。
T23733	Amperozide FG 5606,安哌齐持,Amperozida,Amperozidum	5-HT Receptor	GPCR/G Protein; Neuroscience
	Amperozide (FG 5606) 是一种非典型抗精神病药，可拮抗5-HT2A 受体。它抑制多巴胺的释放并改变多巴胺能神经元的放电。关于该药物使用的调查主要围绕其治疗人类精神分裂症的能力展开。
T4081	MPTP hydrochloride MPTP-hydrochloride	Apoptosis; Dopamine Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	MPTP hydrochloride 是 MPP+ 的前体，是一种多巴胺神经毒素，具有血脑屏障渗透性。MPTP hydrochloride 对多巴胺能神经元有毒，可以导致帕金森症，被广泛应用于帕金森动物模型的构建。
T22781L	FFN 511 hydrochloride FFN 511 hydrochloride(1004548-96-2 Free base)
	FFN 511 hydrochloride 是一种针对神经元囊泡单胺转运体 2 (VMA T2) 的荧光假神经递质 (FFNs)。FFN 511 hydrochloride 可抑制 5-羟色胺与含 VMA T2 的膜结合，可用于标记活体皮质-纹状体急性切片中的多巴胺能神经末梢。激发和发射最大值分别为 406 和 501 nm。
T3624	A-366 A 366,A366	Epigenetic Reader Domain; Histone Methyltransferase	Chromatin/Epigenetic
	A-366 是一种高选择性的肽竞争性组蛋白甲基转移酶 G9a 抑制剂，对 G9a 和 GLP 的 IC50分别为 3.3 和 38 nM。它比其他 21 种甲基转移酶具有 1000 倍以上的选择性。它是 Spindlin1-H3K4me3相互作用的抑制剂，IC50为182.6 nM。它对人 H3R 表现出很高的亲和力，Ki 值为 17 nM，在组胺能和多巴胺能受体家族的亚群间表现出亚型选择性。
T0455	Clozapine 氯氮平,HF 1854,LX 100-129	Dopamine Receptor; Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	Clozapine (HF 1854) 是一种三环二苯二氮卓类药物，属于非典型抗精神病药物。它结合几种类型的中枢神经系统受体，并显示出独特的药理学特征。它是一种血清素拮抗剂，与 5-HT 2A/2C 受体亚型具有强结合力。它还对几种多巴胺能受体表现出很强的亲和力，但对多巴胺 D2 受体仅表现出较弱的拮抗作用，这种受体通常被认为可调节精神抑制活性。
TP2309	NEUROTENSIN TFA (39379-15-2 free base) Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH TFA（55508-42-4 free base),NEUROTENSIN TFA,神经加压素	Others	Others
	Neurotensin TFA (39379-15-2 free base) 是一种内源性 13 个氨基酸的神经肽，具有显着的阿片类非依赖性镇痛作用。它在大脑中充当神经递质，在肠道中充当激素，也充当神经调节剂。由于它与多种神经递质系统如多巴胺能、血清素能、谷氨酸能、GABA 能和胆碱能系统。它具有作为人体代谢物、有丝分裂原、神经递质和创伤的作用。
T61268	Vutiglabridin HSG4112	Phosphatase	Metabolism
	Vutiglabridin (HSG4112) 是一种新型且安全的PON2调节剂，是一个外消旋化合物。Vutiglabridin 是Glabridin 的优化结构类似物，比Glabridin 在减重效果和化学稳定性方面更加优越。Vutiglabridin 通过靶向线粒体对氧磷酶-2改善mptp 诱导的帕金森病小鼠的神经变性。Vutiglabridin 是一种治疗肥胖的临床2期药物，在PD 模型中对对线粒体PON2具有治疗作用。Vutiglabridin 渗透到大脑，结合PON2，恢复1-甲基-4-苯基吡啶(MPP*)诱导的SH-SY5Y 神经母细胞瘤细胞线粒体功能障碍。Vutiglabridin 在小鼠实验中显著减轻了1-甲基-4苯基-1,2,3,6-四氢吡啶(MPTP)诱导的PD 模型小鼠的运动障碍和多巴胺能神经元损伤。
T7626L	Budipine Hydrochloride BY-701,BY 701,BY701,Parkinsan
	Budipine is a non-dopaminergic antiparkinsonian drug. The primary action of budipine is an indirect dopaminergic effect as shown by facilitation of dopamine (DA) release, inhibition of monoamine oxidase type B (MAO-B) and of DA (re) up-take and stimulatio
T26151	RU 41656 RU-41656,RU41656
	RU 41656 is a dopaminergic D2 agonist.
T38202	PAQ
	PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson's disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson's disease induced by MPTP.
T25786	Medifoxamine fumarate LG-152,LG 152,LG152,Geraxyl,Cledial
	Medifoxamine fumarate, an atypical antidepressant, has additional anxiolytic properties acting by dopaminergic and serotonergic mechanisms.
T25247	Cianergoline Cianergolinum
	Cianergoline is a dopaminergic agonist.
T69921	BRF110
	BRF110 is a brain penetrant, potent and selective agonist of nuclear receptor-related 1 (Nurr1):Retinoid X receptor α (RXRα) heterodimer. BRF110 is a neuroprotective agent that prevents dopaminergic neuron demise and striatal dopaminergic denervation in vivo against PD-causing toxins. It induced dopamine biosynthesis in vivo. BRF110 chronic dosing does not induce dyskinesia in mice model.
T68943	Mesulergine
	Mesulergine is metabolized into dopaminergic agonists.
T11937L	m-Tyramine hydrobromide	Others	Others
	m-Tyramine hydrobromide, an endogenous trace amine neuromodulator, influences both the adrenergic and dopaminergic receptors.
T26807	Bifeprunox Mesylate Bifeprunox,DU 127090,DU-127090,DU127090
	Bifeprunox is a partial dopamine and serotonin agonist potentially for the treatment of schizophrenia. Bifeprunox suppresses in vivo VTA dopaminergic neuronal activity via D2 and not D3 dopamine autoreceptor activation. Bifeprunox influences nicotine-seek
T7352L	Pridopidine hydrochloride ASP2314 HCl,Pridopidine HCl,FR310826,ASP-2314 hydrochloride
	Pridopidine Hydrochloride is a dopaminergic stabilizer that has been shown to improve a variety of neurological and psychiatric disorders, including Huntington's disease. Pridopidine Hydrochloride stabilizes psychomotor activity in a state-dependent way t
T39565	L-Glutamic acid-15N
	L-Glutamic acid-15N is the 15N-labeled version of L-Glutamic acid, an excitatory neurotransmitter and an agonist at metabotropic, kainate, NMDA, and AMPA glutamate receptor subtypes. It directly activates the release of dopamine (DA) from dopaminergic terminals.
T68606	Ciladopa hydrochloride
	Ciladopa hydrochloride is a dopaminergic agonist that may be useful in the treatment of Parkinson's disease.
T31903	Galphimine B
	Galphimine B is a cyclodesiccated triterpenoid from Galphimia Glauca, which can regulate the synaptic transmission of dopaminergic ventral tegmental neurons and has a sedative effect.
T35670	Miro1 Reducer
	Promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1). Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 μM). Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.
T37013	(+/-)-PPCC oxalate
	Selective sigma (σ) receptor ligand. Displays high affinity for σ1; also binds at σ2 sites (Ki = 1.5 nM and 50.8 nM respectively). Selective over a range of receptor types including dopaminergic and muscarinic receptors, DAT and SERT. Prezzavento et al (2007) Novel sigma receptor ligands: synthesis and biological profile. J.Med.Chem. 50 951 PMID:17328523 \|Prezzavento et al (2008) A new sigma ligand, (±)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect. Life Sci. 82 549 PMI...
T32701	Levodopa sodium Levodopa
	Levodopa is the naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier, and rapidly taken up by dopaminergic neurons and converted to D
T69129	Clozapine HCl
	Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a ...
T40959	T0467 T0467
	T0467 is a chemical compound that activates the translocation of parkin to the mitochondria in a PINK1-dependent manner in vitro. However, T0467 does not induce the accumulation of PINK1 in the mitochondria of dopaminergic neurons. As a result, T0467 shows promise as a potential compound for activating the PINK1-Parkin signaling pathway and can be utilized in research related to Parkinson's disease and related disorders.

化合物

Cat.No: T7635

Target: Dopamine Receptor

Cat.No: T7626

Target: Others

Cat.No: T9169

Target: Mitochondrial Metabolism, Autophagy

Cat.No: T8637

Synonym: 6-Nitroveratraldehyde,6-硝基藜芦醛

Target: DNA-PK

Cat.No: T0322

Target: Dopamine Receptor, AChR

Cat.No: T8423

Target: Dopamine Receptor, Arrestin

Cat.No: T8357

Target: 5-HT Receptor

Cat.No: T22026

Target: Others, Sirtuin

NS8593 hydrochloride

Cat.No: T12256

Synonym: NS8593 HCl

Target: Potassium Channel

Cat.No: T0412

Synonym: 艾地苯醌,CV-2619

Target: Apoptosis, Antioxidant, Mitochondrial Metabolism

Cat.No: T11277

Synonym: ZK 39106,LSU-65

Target: GABA Receptor

Cat.No: T34616

Synonym: ACR-343,ACR 343,ACR343

Target: Dopamine Receptor

Cat.No: T8653

Target: Dopamine Receptor

Memantine hydrochloride

Cat.No: T1443

Synonym: 3,5-二甲基金刚胺盐酸盐,盐酸美金刚,Namenda,Memantine HCl,D-145 (hydrochloride)

Target: P450, GluR, NMDAR, Autophagy, iGluR

Cat.No: T20993

Target: Others

Cat.No: T13048

Synonym: SC-D

Target: Others

BisfluoroModafinil

Cat.No: T4262

Target: Dopamine Receptor

Opromazine hydrochloride

Cat.No: T50054

Target: Others

Cat.No: TP1310

Target: Neurotensin Receptor

Potassium Channel Activator 1

Cat.No: T10674

Synonym: 钾离子通道激活剂1,ZINC34634569

Target: Potassium Channel

Cat.No: T3106

Target: Apoptosis, Others

Cat.No: T7549

Synonym: SB 223412

Target: Neurokinin receptor

Tiaspirone hydrochloride

Cat.No: T24885L

Synonym: BMY-13859 hydrochloride,Tiaspirone hydrochloride（87691-91-6 Free base)

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T33816

Synonym: ACR-325,ACR 325,ACR325

Target: Dopamine Receptor

Cat.No: T2546

Synonym: R6238,匹莫奇特,匹莫齐特

Target: Potassium Channel, Dopamine Receptor, Adrenergic Receptor, STAT

Cat.No: T23733

Synonym: FG 5606,安哌齐持,Amperozida,Amperozidum

Target: 5-HT Receptor

MPTP hydrochloride

Cat.No: T4081

Synonym: MPTP-hydrochloride

Target: Apoptosis, Dopamine Receptor

FFN 511 hydrochloride

Cat.No: T22781L

Synonym: FFN 511 hydrochloride(1004548-96-2 Free base)

Cat.No: T3624

Synonym: A 366,A366

Target: Epigenetic Reader Domain, Histone Methyltransferase

Cat.No: T0455

Synonym: 氯氮平,HF 1854,LX 100-129

Target: Dopamine Receptor, Adrenergic Receptor, AChR

NEUROTENSIN TFA (39379-15-2 free base)

Cat.No: TP2309

Synonym: Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH TFA（55508-42-4 free base),NEUROTENSIN TFA,神经加压素

Target: Others

Cat.No: T61268

Synonym: HSG4112

Target: Phosphatase

Budipine Hydrochloride

Cat.No: T7626L

Synonym: BY-701,BY 701,BY701,Parkinsan

Cat.No: T26151

Synonym: RU-41656,RU41656

Cat.No: T38202

Medifoxamine fumarate

Cat.No: T25786

Synonym: LG-152,LG 152,LG152,Geraxyl,Cledial

Cat.No: T25247

Synonym: Cianergolinum

Cat.No: T69921

Cat.No: T68943

m-Tyramine hydrobromide

Cat.No: T11937L

Target: Others

Bifeprunox Mesylate

Cat.No: T26807

Synonym: Bifeprunox,DU 127090,DU-127090,DU127090

Pridopidine hydrochloride

Cat.No: T7352L

Synonym: ASP2314 HCl,Pridopidine HCl,FR310826,ASP-2314 hydrochloride

L-Glutamic acid-15N

Cat.No: T39565

Ciladopa hydrochloride

Cat.No: T68606

Cat.No: T31903

Cat.No: T35670

(+/-)-PPCC oxalate

Cat.No: T37013

Levodopa sodium

Cat.No: T32701

Synonym: Levodopa

Cat.No: T69129

Cat.No: T40959

Synonym: T0467

Cat. No.	Product Name	Target	Signaling Pathways
T2A2497	L-Glutamic acid 谷氨酸,(S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,L-谷氨酸,glutacid,Glutaminol	Apoptosis; Ferroptosis; Endogenous Metabolite; iGluR	Apoptosis; Membrane transporter/Ion channel; Metabolism; Neuroscience
	L-Glutamic acid (Glutaminol) 作为一种兴奋性氨基酸神经递质，为谷氨酸盐受体所有亚型的激动剂，对多巴胺从神经末梢释放的过程有激动作用。
T4S1990	Carvacrol 香荆芥酚,Karvakrol,O-Thymol,cymophenol,香芹酚	Apoptosis; Others; Gamma-secretase; Endogenous Metabolite; Antifungal	Apoptosis; Metabolism; Microbiology/Virology; Neuroscience; Others; Proteases/Proteasome; Stem Cells
	Carvacrol (O-Thymol) 是唇形科植物中的一种单萜酚类天然产物，具有镇痛、抗焦虑、抗抑郁、抗氧化、抗炎和抗癌作用。
T5S2357	Acetylcorynoline (+)-Corynoline Acetate,O-Acetylcorynoline,乙酰紫堇灵	Antifungal	Microbiology/Virology
	Acetylcorynoline (O-Acetylcorynoline) 是提取自 Corydalis bungeana 中的一种主要生物碱成分，具有抗炎活性。
T2860	Vanillyl Alcohol 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol	Apoptosis; Others	Apoptosis; Others
	Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) 是一种酚类醇，具有抗血管生成、抗惊厥、抗炎、抗氧化、神经保护和抗伤害活性。它由香兰素衍生而来，在食品和饮料中用作调味剂。
T0848	L-DOPA 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine	Dopamine Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism; Neuroscience
	L-DOPA (Levodopa) 是的神经递质多巴胺的代谢前体，具有口服活性。Levodopa 能够透过血脑屏障，并在大脑中转化为多巴胺。Levodopa 具有抗痛觉过敏作用。Levodopa 还具有帕金森氏病的研究潜力。
T11937	m-Tyramine	Others	Others
	m-Tyramine has effects on the adrenergic and dopaminergic receptor.m-Tyramine is an endogenous trace amine neuromodulator.
TN6524	Irilone
	Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 value of 10.46μM. Irilone potentiat

天然产物

L-Glutamic acid

Cat.No: T2A2497

Synonym: 谷氨酸,(S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,L-谷氨酸,glutacid,Glutaminol

Target: Apoptosis, Ferroptosis, Endogenous Metabolite, iGluR

Cat.No: T4S1990

Synonym: 香荆芥酚,Karvakrol,O-Thymol,cymophenol,香芹酚

Target: Apoptosis, Others, Gamma-secretase, Endogenous Metabolite, Antifungal

Acetylcorynoline

Cat.No: T5S2357

Synonym: (+)-Corynoline Acetate,O-Acetylcorynoline,乙酰紫堇灵

Target: Antifungal

Vanillyl Alcohol

Cat.No: T2860

Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol

Target: Apoptosis, Others

Cat.No: T0848

Synonym: 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine

Target: Dopamine Receptor, Endogenous Metabolite

Cat.No: T11937

Target: Others

Cat.No: TN6524

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