首页工具

登录

搜索结果

Search Results for " antihyperglycemic "

22

抑制剂 & 化合物

18

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T26712	AZD-1656 AZD 1656	Glucokinase	Metabolism
	AZD-1656 是口服有效的葡萄糖激酶选择性激活剂，EC50为 60 nM。AZD1656在2 型糖尿病中有研究的价值。
T0334	Rosiglitazone BRL49653,罗格列酮	Ferroptosis; TRP/TRPV Channel; PPAR; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Rosiglitazone (BRL49653) 是一种 PPARγ 激动剂、TRPC5 激活剂和 TRPM3 抑制剂，具有口服活性。Rosiglitazone 也是一种降糖剂，是噻唑烷二酮类胰岛素增敏剂。
T1502	Vildagliptin 维达列汀,NVP-LAF 237,维格列汀,LAF237	Apoptosis; Ferroptosis; Proteasome; DPP-4	Apoptosis; Proteases/Proteasome; Ubiquitination
	Vildagliptin (LAF237) 是一种选择性二肽基肽酶IV (DPP-IV) 抑制剂，在人 Caco-2 细胞中抑制 DPP-IV 的IC50为 3.5 nM。它具有出色的口服生物利用度和降血糖活性。
T6646	Rosiglitazone hydrochloride 盐酸罗格列酮,BRL-49653 HCl,Rosiglitazone HCl	Ferroptosis; TRP/TRPV Channel; PPAR; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Rosiglitazone hydrochloride (BRL-49653 HCl) 是一种降血糖药物，通过与脂肪细胞中的 PPAR 受体结合来刺激胰岛素分泌。它对 PPARγ1、PPARγ2 和 PPARγ 的EC50值分别为 30 nM、100 nM 和 60 nM。它也是TRPC5的激活剂和TRPM3的抑制剂。
T3547	Sotagliflozin LX-4211,LP-802034	SGLT	GPCR/G Protein
	Sotagliflozin (LP-802034) 是有效的SGLT1/2抑制剂，用作抗糖尿病剂。
T21764	MCC-555 Isaglitazone,Netoglitazone	PPAR	DNA Damage/DNA Repair; Metabolism
	MCC-555 (Isaglitazone) 是一种 PPARα 和 PPARγ 激动剂，具有抗高血糖作用。
T8493	Ingliforib GPi 296,CP 368296	Phosphorylase	Metabolism
	Ingliforib (CP 368296) 是glycogen phosphorylase 抑制剂，能够抑制肝脏、肌肉和大脑的 glycogen phosphorylase ，其IC50值分别为 52，352 和 150 nM，具有心脏保护的作用。
T1527	Gliclazide 格列齐特,S1702,SE1702	Potassium Channel	Membrane transporter/Ion channel
	Gliclazide (SE1702) 是一种有效的全细胞的 β 细胞 ATP 敏感型钾流阻断剂，IC50为 184 nM，用作降糖药。
T1453	Phenformin hydrochloride Phenformin HCl,Phenethylbiguanide hydrochloride,盐酸苯乙福明	Potassium Channel; AMPK; Autophagy	Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; PI3K/Akt/mTOR signaling
	Phenformin hydrochloride (Phenformin HCl) 是一种具有抗高血糖活性的双胍类抗糖尿病药物，能够使 AMPK 活化。
T2389	Dapagliflozin 达格列净,BMS-512148	SGLT; HIF	Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein
	Dapagliflozin (BMS-512148) 竞争性的葡萄糖协同转运蛋白2 (SGLT2) 抑制剂，可促进尿液中葡萄糖的排泄，在糖尿病 (DM) 研究中具有价值。Dapagliflozin 诱导 HIF1表达并减轻肾脏 IR 损伤。
T0371	Gliquidone AR-DF 26,格列喹酮,Glurenorm	Potassium Channel	Membrane transporter/Ion channel
	Gliquidone (AR-DF 26) 是一种磺酰脲类的抗糖尿病药物，可用于2型糖尿病的研究。
T28560	Ro 16-8714 Ro-16-8714,Ro16-8714
	Ro 16-8714 is an agonist of beta-adrenoreceptor with antihyperglycemic and thermogenic properties.
T68561	ASP-4000 free base
	ASP-4000 free base is a dipeptidyl peptidase 4 (DPP) inhibitor with antihyperglycemic activity.
T24164	Indanorex JL-11698,Dietor,JL11698,Indanorexum,JL 11698
	Indanorex is a stimulant drug. It has appetite suppressant effects and also has antihyperglycemic effects.
T15505	HSK0935 HSK 0935,HSK-0935	SGLT	GPCR/G Protein
	HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has antihyperglycemic activities.
T15386	Glisoxepide	Others	Others
	Glisoxepide is a sulphonamide derivative and is an orally available nonselective K(ATP) channel blocker. It has antihyperglycemic activity and cardiovascular regulation effect.
T69015	THR-0921
	THR-0921 is a peroxisome proliferator-activated gamma (PPAR gamma) agonist that has antihyperglycemic activity with low adipogenic potential.
T31960	Glymidine Glycodiazin,Glymidinum,Glycodiazine,Glidiazine
	Glycodiazine is a sulfadiazine derivative with antihyperglycemic activity. Glycanamidine can lower blood sugar levels by increasing insulin release from pancreatic beta cells and increasing peripheral tissue sensitivity to insulin.
T61076	Vildagliptin dihydrate
	Vildagliptin dihydrate (LAF237 dihydrate) is a powerful and stable dipeptidyl peptidase IV (DPP-IV) inhibitor, demonstrating selectivity with an IC50 of 3.5 nM in human Caco-2 cells. This compound exhibits exceptional oral bioavailability and significant antihyperglycemic activity [1].
T76310	Acetyl Gastric Inhibitory Peptide (human)
	AcetylGastric Inhibitory Peptide(human)，一种脂肪酸衍生的葡萄糖依赖性胰岛素多肽类似物，具备改善抗高血糖和胰岛素敏感性的特性。适用于糖尿病、胰岛素抵抗及肥胖研究。
T78543	Acetyl Gastric Inhibitory Peptide (human) TFA Human N-acetyl GIP TFA
	AcetylGastric Inhibitory Peptide(human) TFA 是一种葡萄糖依赖性胰岛素释放多肽的改性脂肪酸衍生物，具有增强的抗高血糖和促胰岛素作用。它主要用于糖尿病、胰岛素抵抗和肥胖的科研领域。
T73779	5β-Androstan-3β-ol-17-one
	5β-Androstan-3β-ol-17-one（3β-Etiocholanolone；5β-Epiandrosterone），为5β还原型类固醇，主要是脱氢表雄酮（DHEA）的关键代谢物之一。在C57BL/KsJ基因型糖尿病（db/db）小鼠中，该化合物显示出显著的降糖效果，并且具有对神经元的抑制活性。

化合物

Cat.No: T26712

Synonym: AZD 1656

Target: Glucokinase

Cat.No: T0334

Synonym: BRL49653,罗格列酮

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Cat.No: T1502

Synonym: 维达列汀,NVP-LAF 237,维格列汀,LAF237

Target: Apoptosis, Ferroptosis, Proteasome, DPP-4

Rosiglitazone hydrochloride

Cat.No: T6646

Synonym: 盐酸罗格列酮,BRL-49653 HCl,Rosiglitazone HCl

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Cat.No: T3547

Synonym: LX-4211,LP-802034

Target: SGLT

Cat.No: T21764

Synonym: Isaglitazone,Netoglitazone

Target: PPAR

Cat.No: T8493

Synonym: GPi 296,CP 368296

Target: Phosphorylase

Cat.No: T1527

Synonym: 格列齐特,S1702,SE1702

Target: Potassium Channel

Phenformin hydrochloride

Cat.No: T1453

Synonym: Phenformin HCl,Phenethylbiguanide hydrochloride,盐酸苯乙福明

Target: Potassium Channel, AMPK, Autophagy

Cat.No: T2389

Synonym: 达格列净,BMS-512148

Target: SGLT, HIF

Cat.No: T0371

Synonym: AR-DF 26,格列喹酮,Glurenorm

Target: Potassium Channel

Cat.No: T28560

Synonym: Ro-16-8714,Ro16-8714

ASP-4000 free base

Cat.No: T68561

Cat.No: T24164

Synonym: JL-11698,Dietor,JL11698,Indanorexum,JL 11698

Cat.No: T15505

Synonym: HSK 0935,HSK-0935

Target: SGLT

Cat.No: T15386

Target: Others

Cat.No: T69015

Cat.No: T31960

Synonym: Glycodiazin,Glymidinum,Glycodiazine,Glidiazine

Vildagliptin dihydrate

Cat.No: T61076

Acetyl Gastric Inhibitory Peptide (human)

Cat.No: T76310

Acetyl Gastric Inhibitory Peptide (human) TFA

Cat.No: T78543

Synonym: Human N-acetyl GIP TFA

5β-Androstan-3β-ol-17-one

Cat.No: T73779

Cat. No.	Product Name	Target	Signaling Pathways
T0247	Acarbose 阿卡波糖,BAY g 5421	Glucosidase	Metabolism
	Acarbose (BAY g 5421) 是一种具有口服具有活力 α-葡萄糖苷酶 (alpha-glucosidase) 抑制剂 (IC50=11 nM)，是一种降糖药。它能提高磺脲类药物或胰岛素的降血糖作用。
T3675	1-Deoxynojirimycin Duvoglustat,Moranoline,1-脱氧野尻霉素,moranolin	PI3K; Glucosidase	Metabolism; PI3K/Akt/mTOR signaling
	1-Deoxynojirimycin (Moranoline) 是一种口服具有活性的 α-葡萄糖苷酶抑制剂。它具有降血糖、减肥和抗病毒的活性。它抑制餐后血糖，预防糖尿病。
T21344	1-Deoxynojirimycin hydrochloride Moranoline,去氧野艽霉素盐酸盐,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin	PI3K; Antibacterial; Antibiotic; Glucosidase	Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling
	1-Deoxynojirimycin hydrochloride (Moranoline) 是一种口服有效的 α-葡萄糖苷酶抑制剂，具有降血糖、减肥和抗病毒的作用，可抑制餐后血糖，预防糖尿病。
T1529	Miglitol BAY1099,米格列醇,BAY-m1099	Others	Others
	Miglitol (BAY1099) 是一种口服抗糖尿病化合物，能够抑制糖复合体分解为葡萄糖。
TN1026	Vomicine 番木虌次碱,番木鳖次碱	Others	Others
	Vomicine 是一种具有抗糖尿病活性的生物碱。
T7448	4-Hydroxyisoleucine 4-羟基-L-异亮氨酸,4-Hydroxy-L-isoleucine	Others	Others
	4-Hydroxyisoleucine (4-Hydroxy-L-isoleucine) 是从胡芦巴种子中提取和纯化的一种氨基酸，具有促胰岛素作用。
T5743	Gymnemagenin	Liver X Receptor	Metabolism
	Gymnemagenin 是一种分离自G. sylvestre 的三萜。它具有抗病毒作用，对糖尿病和肥胖症具有潜在的研究价值。
TN2247	Swertisin	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Swertisin 是从日本紫菜中分离出的 C-葡萄糖基黄酮，是腺苷 A1 受体拮抗剂，具有抗糖尿病、抗炎和抗氧化作用。
TN1334	7-Methoxyrosmanol 7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol	cAMP	GPCR/G Protein
	7-Methoxyrosmanol (7-O-Methylrosmanol) 是一种酚类二萜，从迷迭香中分离得到，可抑制 PEPCK 和 G6Pase 启动子的 cAMP 反应。
T6S1371	Isovitexin Homovitexin,Saponaretin,Apigenin-6-C-Glucoside,异牡荆黄素	NF-κB; JNK; Glucosidase	MAPK; Metabolism; NF-κB
	Isovitexin (Apigenin-6-C-Glucoside) 是从亚洲水稻种得到的一种黄酮，具有抗氧化和抗炎活性。它的作用与JNK1/2的抑制剂类似，抑制NF-κB 的活化。
T7846	Aegeline	Others; Antifungal	Microbiology/Virology; Others
	Aegeline 是从 Aegle marmelos 的叶子中分离出来的一种生物碱酰胺，有抗高血糖和抗血脂异常的活性。
T3S2072	3-Butylidenephthalide Butylidene phthalide,n-Butylidenephthalide,丁烯基苯酞,丁烯基苯酞；丁烯基酞内酯	Parasite; Glucosidase	Metabolism; Microbiology/Virology
	3-Butylidenephthalide (Butylidene phthalide) 是从 Ligusticum chuanxiongHort 鉴定出的一种邻苯二甲酸酐衍生物，有杀虫活性。
T3415	Secoisolariciresinol diglucoside 亚麻木酚素,LGM2605	ROS	Immunology/Inflammation
	Secoisolariciresinol diglucoside (LGM2605) 在铁过载诱导的氧化还原炎症损伤的体外模型中具有细胞保护作用。 Secoisolariciresinol Diglucoside(25 mg/kg b.w.) 通过抑制 ROS 水平介导的酶和非酶抗氧化剂水平升高来防止肝脏受到过氧化损伤，从而发挥抗高血糖作用。
T2909	Fraxetin 7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀	Apoptosis; Others	Apoptosis; Others
	Fraxetin (7,8-dihydroxy-6-methoxy coumarin) 是从秦皮中分离出来的一种天然产物，可诱导细胞凋亡，具有抗肿瘤、抗氧化作用和抗炎作用。
T75493	Ellipyrone B
	Ellipyrone B，一种大环肽，对二肽基肽酶 4 (dipeptidyl peptidase-4: IC50=0.48 mM) 表现出抑制作用。
T60692	Masoprocol
	Masoprocol (meso-Nordihydroguaiaretic acid) 是口服有效的脂氧合酶 (lipoxygenase) 抑制剂。Masoprocol 具有出抗高血糖活性，可用于 II 型糖尿病的研究。 Masoprocol 可降低体内肝甘油三酯和葡萄糖浓度。
TN4585	Moronic acid	HIV Protease; Antifection; HSV	Microbiology/Virology; Proteases/Proteasome
	Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an...
TN4584	Morolic acid	IL Receptor; COX; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro

天然产物

Cat.No: T0247

Synonym: 阿卡波糖,BAY g 5421

Target: Glucosidase

1-Deoxynojirimycin

Cat.No: T3675

Synonym: Duvoglustat,Moranoline,1-脱氧野尻霉素,moranolin

Target: PI3K, Glucosidase

1-Deoxynojirimycin hydrochloride

Cat.No: T21344

Synonym: Moranoline,去氧野艽霉素盐酸盐,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin

Target: PI3K, Antibacterial, Antibiotic, Glucosidase

Cat.No: T1529

Synonym: BAY1099,米格列醇,BAY-m1099

Target: Others

Cat.No: TN1026

Synonym: 番木虌次碱,番木鳖次碱

Target: Others

4-Hydroxyisoleucine

Cat.No: T7448

Synonym: 4-羟基-L-异亮氨酸,4-Hydroxy-L-isoleucine

Target: Others

Cat.No: T5743

Target: Liver X Receptor

Cat.No: TN2247

Target: Adenosine Receptor

7-Methoxyrosmanol

Cat.No: TN1334

Synonym: 7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol

Target: cAMP

Cat.No: T6S1371

Synonym: Homovitexin,Saponaretin,Apigenin-6-C-Glucoside,异牡荆黄素

Target: NF-κB, JNK, Glucosidase

Cat.No: T7846

Target: Others, Antifungal

3-Butylidenephthalide

Cat.No: T3S2072

Synonym: Butylidene phthalide,n-Butylidenephthalide,丁烯基苯酞,丁烯基苯酞；丁烯基酞内酯

Target: Parasite, Glucosidase

Secoisolariciresinol diglucoside

Cat.No: T3415

Synonym: 亚麻木酚素,LGM2605

Target: ROS

Cat.No: T2909

Synonym: 7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀

Target: Apoptosis, Others

Cat.No: T75493

Cat.No: T60692

Cat.No: TN4585

Target: HIV Protease, Antifection, HSV

Cat.No: TN4584

Target: IL Receptor, COX, HIV Protease

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼